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12D miR HR13_24
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Results for Ar
Z-value: 1.05
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Transcription factors associated with Ar
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Ar | mm10_v2_chrX_+_98149666_98149721 | 0.43 | 1.9e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr14_-_5455467 Show fit | 1.20 |
ENSMUST00000180867.1
|
predicted gene 3194 |
|
| chr14_-_7090812 Show fit | 1.17 |
ENSMUST00000179898.1
|
predicted gene 3696 |
|
| chr2_+_119167758 Show fit | 1.05 |
ENSMUST00000057454.3
|
GTP cyclohydrolase I feedback regulator |
|
| chr14_+_65806066 Show fit | 1.04 |
ENSMUST00000139644.1
|
PDZ binding kinase |
|
| chr7_-_97417730 Show fit | 1.02 |
ENSMUST00000043077.7
|
thyroid hormone responsive |
|
| chr14_-_6742332 Show fit | 0.92 |
ENSMUST00000163850.1
|
predicted gene 3636 |
|
| chr14_+_4023941 Show fit | 0.91 |
ENSMUST00000096184.4
|
predicted gene 5796 |
|
| chr14_+_3688783 Show fit | 0.88 |
ENSMUST00000170639.1
|
predicted gene 3043 |
|
| chr14_-_6875155 Show fit | 0.86 |
ENSMUST00000170465.2
|
predicted gene 3636 |
|
| chr8_-_13254154 Show fit | 0.83 |
ENSMUST00000033825.4
|
ADP-ribosylhydrolase like 1 |
Network of associatons between targets according to the STRING database.
First level regulatory network of Ar
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.5 | GO:0032435 | negative regulation of proteasomal ubiquitin-dependent protein catabolic process(GO:0032435) |
| 0.2 | 1.2 | GO:0051725 | protein de-ADP-ribosylation(GO:0051725) |
| 0.0 | 1.1 | GO:0014003 | oligodendrocyte development(GO:0014003) |
| 0.1 | 1.0 | GO:0006003 | fructose 2,6-bisphosphate metabolic process(GO:0006003) |
| 0.0 | 1.0 | GO:0010866 | regulation of triglyceride biosynthetic process(GO:0010866) |
| 0.2 | 0.8 | GO:0002540 | leukotriene production involved in inflammatory response(GO:0002540) |
| 0.2 | 0.8 | GO:0060025 | regulation of synaptic activity(GO:0060025) |
| 0.0 | 0.8 | GO:0051497 | negative regulation of stress fiber assembly(GO:0051497) |
| 0.0 | 0.8 | GO:0071158 | positive regulation of cell cycle arrest(GO:0071158) |
| 0.1 | 0.7 | GO:2000275 | regulation of oxidative phosphorylation uncoupler activity(GO:2000275) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.1 | GO:0048770 | melanosome(GO:0042470) pigment granule(GO:0048770) |
| 0.1 | 0.7 | GO:0034991 | nuclear meiotic cohesin complex(GO:0034991) |
| 0.0 | 0.7 | GO:0033270 | paranode region of axon(GO:0033270) |
| 0.0 | 0.7 | GO:0042588 | zymogen granule(GO:0042588) |
| 0.0 | 0.7 | GO:0032281 | AMPA glutamate receptor complex(GO:0032281) |
| 0.0 | 0.6 | GO:0005763 | organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763) |
| 0.0 | 0.5 | GO:0061700 | GATOR2 complex(GO:0061700) |
| 0.0 | 0.5 | GO:0045179 | apical cortex(GO:0045179) |
| 0.0 | 0.5 | GO:0097539 | ciliary transition fiber(GO:0097539) |
| 0.0 | 0.5 | GO:0005641 | nuclear envelope lumen(GO:0005641) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 1.8 | GO:0004556 | alpha-amylase activity(GO:0004556) |
| 0.3 | 1.2 | GO:0003875 | ADP-ribosylarginine hydrolase activity(GO:0003875) |
| 0.1 | 1.2 | GO:0031078 | histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041) |
| 0.1 | 1.0 | GO:0004331 | 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331) |
| 0.0 | 1.0 | GO:0030742 | GTP-dependent protein binding(GO:0030742) |
| 0.3 | 0.8 | GO:0004051 | arachidonate 5-lipoxygenase activity(GO:0004051) |
| 0.1 | 0.8 | GO:0010181 | FMN binding(GO:0010181) |
| 0.2 | 0.7 | GO:0050656 | 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656) |
| 0.1 | 0.7 | GO:0004095 | carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416) |
| 0.2 | 0.6 | GO:0031403 | lithium ion binding(GO:0031403) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.3 | PID HDAC CLASSII PATHWAY | Signaling events mediated by HDAC Class II |
| 0.0 | 0.6 | PID HNF3B PATHWAY | FOXA2 and FOXA3 transcription factor networks |
| 0.0 | 0.5 | PID TCR JNK PATHWAY | JNK signaling in the CD4+ TCR pathway |
| 0.0 | 0.5 | PID RHODOPSIN PATHWAY | Visual signal transduction: Rods |
| 0.0 | 0.5 | ST MYOCYTE AD PATHWAY | Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway. |
| 0.0 | 0.3 | ST GRANULE CELL SURVIVAL PATHWAY | Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway. |
| 0.0 | 0.2 | SA FAS SIGNALING | The TNF-type receptor Fas induces apoptosis on ligand binding. |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 1.2 | REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION | Genes involved in NOTCH1 Intracellular Domain Regulates Transcription |
| 0.1 | 1.0 | REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION | Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation |
| 0.0 | 1.0 | REACTOME MEIOTIC SYNAPSIS | Genes involved in Meiotic Synapsis |
| 0.0 | 0.7 | REACTOME CGMP EFFECTS | Genes involved in cGMP effects |
| 0.0 | 0.6 | REACTOME GLYCOLYSIS | Genes involved in Glycolysis |
| 0.1 | 0.5 | REACTOME CREATION OF C4 AND C2 ACTIVATORS | Genes involved in Creation of C4 and C2 activators |
| 0.0 | 0.5 | REACTOME INTERACTION BETWEEN L1 AND ANKYRINS | Genes involved in Interaction between L1 and Ankyrins |
| 0.0 | 0.4 | REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE | Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere |
| 0.0 | 0.3 | REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC | Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC |
| 0.0 | 0.3 | REACTOME RNA POL I TRANSCRIPTION TERMINATION | Genes involved in RNA Polymerase I Transcription Termination |