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12D miR HR13_24
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Results for Cebpb
Z-value: 1.55
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Transcription factors associated with Cebpb
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Cebpb | mm10_v2_chr2_+_167688915_167688973 | 0.02 | 9.5e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr2_-_32387760 Show fit | 3.06 |
ENSMUST00000050785.8
|
lipocalin 2 |
|
| chr2_+_24345282 Show fit | 2.90 |
ENSMUST00000114485.2
|
interleukin 1 receptor antagonist |
|
| chr13_-_52981027 Show fit | 2.78 |
ENSMUST00000071065.7
|
nuclear factor, interleukin 3, regulated |
|
| chr5_-_123865491 Show fit | 2.49 |
ENSMUST00000057145.5
|
niacin receptor 1 |
|
| chr2_+_24345305 Show fit | 2.19 |
ENSMUST00000114482.1
|
interleukin 1 receptor antagonist |
|
| chr2_+_119351222 Show fit | 2.16 |
ENSMUST00000028780.3
|
ChaC, cation transport regulator 1 |
|
| chr14_+_41105359 Show fit | 2.04 |
ENSMUST00000047286.6
|
methionine adenosyltransferase I, alpha |
|
| chr17_+_48346465 Show fit | 1.95 |
ENSMUST00000113237.3
|
triggering receptor expressed on myeloid cells 2 |
|
| chr17_+_48346401 Show fit | 1.92 |
ENSMUST00000024791.8
|
triggering receptor expressed on myeloid cells 2 |
|
| chr4_+_106622424 Show fit | 1.76 |
ENSMUST00000047922.2
|
tetratricopeptide repeat domain 22 |
Network of associatons between targets according to the STRING database.
First level regulatory network of Cebpb
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.1 | 5.7 | GO:2000660 | negative regulation of interleukin-1-mediated signaling pathway(GO:2000660) |
| 0.7 | 4.5 | GO:1902998 | regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998) |
| 1.3 | 3.9 | GO:0002582 | positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002582) positive regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002588) |
| 0.5 | 3.1 | GO:1901678 | iron coordination entity transport(GO:1901678) |
| 0.1 | 2.8 | GO:0071353 | cellular response to interleukin-4(GO:0071353) |
| 0.5 | 2.5 | GO:0038094 | Fc-gamma receptor signaling pathway(GO:0038094) |
| 0.2 | 2.2 | GO:0006751 | glutathione catabolic process(GO:0006751) |
| 0.5 | 2.0 | GO:0006556 | S-adenosylmethionine biosynthetic process(GO:0006556) |
| 0.6 | 1.9 | GO:0033189 | response to vitamin A(GO:0033189) |
| 0.2 | 1.9 | GO:0035021 | negative regulation of Rac protein signal transduction(GO:0035021) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 16.8 | GO:0005615 | extracellular space(GO:0005615) |
| 0.3 | 4.5 | GO:0097418 | neurofibrillary tangle(GO:0097418) |
| 0.2 | 1.8 | GO:0005577 | fibrinogen complex(GO:0005577) |
| 0.2 | 1.5 | GO:0046696 | lipopolysaccharide receptor complex(GO:0046696) |
| 0.1 | 1.3 | GO:0098644 | complex of collagen trimers(GO:0098644) |
| 0.0 | 1.3 | GO:0016363 | nuclear matrix(GO:0016363) |
| 0.2 | 1.2 | GO:0031838 | haptoglobin-hemoglobin complex(GO:0031838) |
| 0.0 | 1.2 | GO:0005581 | collagen trimer(GO:0005581) |
| 0.0 | 1.2 | GO:0005902 | microvillus(GO:0005902) |
| 0.0 | 1.2 | GO:0016605 | PML body(GO:0016605) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.7 | 5.1 | GO:0005151 | interleukin-1, Type II receptor binding(GO:0005151) interleukin-1 receptor antagonist activity(GO:0005152) interleukin-1 Type I receptor antagonist activity(GO:0045352) interleukin-1 Type II receptor antagonist activity(GO:0045353) |
| 0.6 | 5.1 | GO:0070891 | lipoteichoic acid binding(GO:0070891) |
| 0.2 | 4.5 | GO:0051787 | misfolded protein binding(GO:0051787) |
| 0.0 | 4.5 | GO:0004867 | serine-type endopeptidase inhibitor activity(GO:0004867) |
| 0.0 | 3.1 | GO:0002020 | protease binding(GO:0002020) |
| 0.4 | 2.2 | GO:0003839 | gamma-glutamylcyclotransferase activity(GO:0003839) |
| 0.0 | 2.0 | GO:0016765 | transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765) |
| 0.3 | 1.8 | GO:0004499 | N,N-dimethylaniline monooxygenase activity(GO:0004499) |
| 0.0 | 1.8 | GO:0005518 | collagen binding(GO:0005518) |
| 0.0 | 1.6 | GO:0005104 | fibroblast growth factor receptor binding(GO:0005104) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 6.8 | PID IL1 PATHWAY | IL1-mediated signaling events |
| 0.1 | 4.5 | PID MYC REPRESS PATHWAY | Validated targets of C-MYC transcriptional repression |
| 0.0 | 3.9 | NABA ECM REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
| 0.1 | 2.3 | PID TOLL ENDOGENOUS PATHWAY | Endogenous TLR signaling |
| 0.0 | 2.2 | NABA ECM AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
| 0.1 | 2.0 | NABA PROTEOGLYCANS | Genes encoding proteoglycans |
| 0.0 | 1.2 | PID PDGFRA PATHWAY | PDGFR-alpha signaling pathway |
| 0.0 | 1.1 | PID INTEGRIN5 PATHWAY | Beta5 beta6 beta7 and beta8 integrin cell surface interactions |
| 0.0 | 1.1 | PID IL12 2PATHWAY | IL12-mediated signaling events |
| 0.0 | 0.9 | ST MYOCYTE AD PATHWAY | Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway. |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 6.2 | REACTOME IL1 SIGNALING | Genes involved in Interleukin-1 signaling |
| 0.0 | 4.6 | REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 | Genes involved in Response to elevated platelet cytosolic Ca2+ |
| 0.1 | 3.9 | REACTOME OTHER SEMAPHORIN INTERACTIONS | Genes involved in Other semaphorin interactions |
| 0.2 | 2.3 | REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 | Genes involved in IKK complex recruitment mediated by RIP1 |
| 0.0 | 2.3 | REACTOME SIGNALING BY RHO GTPASES | Genes involved in Signaling by Rho GTPases |
| 0.1 | 2.0 | REACTOME SULFUR AMINO ACID METABOLISM | Genes involved in Sulfur amino acid metabolism |
| 0.1 | 1.9 | REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS | Genes involved in Phase 1 - Functionalization of compounds |
| 0.0 | 1.4 | REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES | Genes involved in Chemokine receptors bind chemokines |
| 0.1 | 1.3 | REACTOME CS DS DEGRADATION | Genes involved in CS/DS degradation |
| 0.0 | 1.3 | REACTOME METAL ION SLC TRANSPORTERS | Genes involved in Metal ion SLC transporters |