ISMARA results: Elf3

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12D miR HR13_24

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Results for Elf3

Z-value: 1.11

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Transcription factors associated with Elf3

Gene Symbol	Gene ID	Gene Info
Elf3 Ensembl NCBI MGI UniProt	ENSMUSG00000003051.7	E74-like factor 3

Activity-expression correlation:

Gene	Promoter	Pearson corr. coef.	P-value	Plot
Elf3	mm10_v2_chr1_-_135258449_135258472	0.17	6.3e-01	Click!

Activity profile of Elf3 motif

Sorted Z-values of Elf3 motif

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Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr1_+_16688405 Show fit	2.24	ENSMUST00000026881.4	Ly96 Ensembl NCBI MGI UniProt Show fit	lymphocyte antigen 96
chrX_+_11308824 Show fit	2.06	ENSMUST00000178595.1	Gm14476 Ensembl NCBI MGI UniProt Show fit	predicted gene 14476
chrX_+_11324659 Show fit	2.05	ENSMUST00000164729.2	Gm14475 Ensembl NCBI MGI UniProt Show fit	predicted gene 14475
chrX_+_11302432 Show fit	2.01	ENSMUST00000179428.1	Gm14474 Ensembl NCBI MGI UniProt Show fit	predicted gene 14474
chr16_+_5007283 Show fit	1.92	ENSMUST00000184439.1	Smim22 Ensembl NCBI MGI UniProt Show fit	small integral membrane protein 22
chrX_+_11321423 Show fit	1.90	ENSMUST00000178196.1	Gm14478 Ensembl NCBI MGI UniProt Show fit	predicted gene 14478
chrX_+_73123068 Show fit	1.51	ENSMUST00000179117.1	Gm14685 Ensembl NCBI MGI UniProt Show fit	predicted gene 14685
chrX_+_11299257 Show fit	1.35	ENSMUST00000178729.1	Gm14483 Ensembl NCBI MGI UniProt Show fit	predicted gene 14483
chr7_-_3677509 Show fit	1.33	ENSMUST00000038743.8	Tmc4 Ensembl NCBI MGI UniProt Show fit	transmembrane channel-like gene family 4
chrX_+_11318256 Show fit	1.27	ENSMUST00000179859.1	Gm14482 Ensembl NCBI MGI UniProt Show fit	predicted gene 14482

Showing 1 to 10 of 200 entries

Network of associatons between targets according to the STRING database.

First level regulatory network of Elf3

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.4	2.2	GO:0032497	detection of lipopolysaccharide(GO:0032497)
0.1	2.1	GO:0060363	cranial suture morphogenesis(GO:0060363)
0.3	1.0	GO:1903575	cornified envelope assembly(GO:1903575)
0.2	1.0	GO:1903237	negative regulation of leukocyte tethering or rolling(GO:1903237)
0.1	1.0	GO:0036462	TRAIL-activated apoptotic signaling pathway(GO:0036462)
0.0	1.0	GO:0038083	peptidyl-tyrosine autophosphorylation(GO:0038083)
0.3	0.9	GO:0009972	cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
0.0	0.9	GO:0033327	Leydig cell differentiation(GO:0033327)
0.2	0.8	GO:0015801	aromatic amino acid transport(GO:0015801) tryptophan transport(GO:0015827)
0.2	0.8	GO:1990839	response to endothelin(GO:1990839)

Showing 1 to 10 of 122 entries

Gene overrepresentation in cellular component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.3	2.2	GO:0046696	lipopolysaccharide receptor complex(GO:0046696)
0.3	2.1	GO:0032937	SREBP-SCAP-Insig complex(GO:0032937)
0.0	1.5	GO:0042101	T cell receptor complex(GO:0042101)
0.3	1.0	GO:0030690	Noc1p-Noc2p complex(GO:0030690)
0.0	0.8	GO:0016581	NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0	0.7	GO:0001772	immunological synapse(GO:0001772)
0.1	0.6	GO:0044194	cytolytic granule(GO:0044194)
0.1	0.6	GO:0097197	tetraspanin-enriched microdomain(GO:0097197)
0.0	0.6	GO:0030904	retromer complex(GO:0030904)
0.0	0.5	GO:0008250	oligosaccharyltransferase complex(GO:0008250)

Showing 1 to 10 of 35 entries

Gene overrepresentation in molecular function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.4	2.2	GO:0001875	lipopolysaccharide receptor activity(GO:0001875)
0.0	1.6	GO:0004715	non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0	1.4	GO:0008009	chemokine activity(GO:0008009)
0.1	1.2	GO:0050786	RAGE receptor binding(GO:0050786)
0.0	1.2	GO:0005035	tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.2	1.0	GO:0035877	death effector domain binding(GO:0035877)
0.1	0.9	GO:0004126	cytidine deaminase activity(GO:0004126)
0.0	0.9	GO:0015125	bile acid transmembrane transporter activity(GO:0015125)
0.2	0.8	GO:0048408	epidermal growth factor binding(GO:0048408)
0.1	0.8	GO:0008241	peptidyl-dipeptidase activity(GO:0008241)

Showing 1 to 10 of 74 entries

Gene overrepresentation in curated gene sets: canonical pathways category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	2.5	PID TOLL ENDOGENOUS PATHWAY	Endogenous TLR signaling
0.0	1.5	SA B CELL RECEPTOR COMPLEXES	Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0	1.4	PID TCR PATHWAY	TCR signaling in naïve CD4+ T cells
0.1	1.0	SA FAS SIGNALING	The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0	1.0	PID IL12 STAT4 PATHWAY	IL12 signaling mediated by STAT4
0.0	1.0	PID UPA UPAR PATHWAY	Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0	0.9	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
0.0	0.9	PID AJDISS 2PATHWAY	Posttranslational regulation of adherens junction stability and dissassembly
0.0	0.8	PID NFAT TFPATHWAY	Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0	0.6	PID CD40 PATHWAY	CD40/CD40L signaling

Showing 1 to 10 of 15 entries

Gene overrepresentation in curated gene sets: REACTOME pathways category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.2	2.2	REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1	Genes involved in IKK complex recruitment mediated by RIP1
0.1	1.0	REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10	Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0	0.9	REACTOME PYRIMIDINE METABOLISM	Genes involved in Pyrimidine metabolism
0.0	0.8	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	0.8	REACTOME SIGNAL ATTENUATION	Genes involved in Signal attenuation
0.0	0.8	REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES	Genes involved in Chemokine receptors bind chemokines
0.0	0.7	REACTOME REGULATION OF SIGNALING BY CBL	Genes involved in Regulation of signaling by CBL
0.0	0.7	REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.1	0.6	REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE	Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0	0.5	REACTOME METABOLISM OF POLYAMINES	Genes involved in Metabolism of polyamines

Showing 1 to 10 of 29 entries

Results for Elf3

Z-value: 1.11

Motif logo

Transcription factors associated with Elf3

Activity-expression correlation:

Activity profile of Elf3 motif

Sorted Z-values of Elf3 motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of Elf3

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: