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12D miR HR13_24
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Results for Erg
Z-value: 1.84
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Transcription factors associated with Erg
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Erg | mm10_v2_chr16_-_95586585_95586595 | 0.88 | 3.0e-04 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr16_-_44333135 Show fit | 4.12 |
ENSMUST00000047446.6
|
SID1 transmembrane family, member 1 |
|
| chr16_-_44332925 Show fit | 4.09 |
ENSMUST00000136381.1
|
SID1 transmembrane family, member 1 |
|
| chr17_+_34048280 Show fit | 3.74 |
ENSMUST00000143354.1
|
collagen, type XI, alpha 2 |
|
| chr15_-_98807910 Show fit | 3.46 |
ENSMUST00000075444.6
|
dendrin |
|
| chr1_+_40515362 Show fit | 3.36 |
ENSMUST00000027237.5
|
interleukin 18 receptor accessory protein |
|
| chr9_-_54661870 Show fit | 2.88 |
ENSMUST00000034822.5
|
acyl-CoA synthetase bubblegum family member 1 |
|
| chr8_+_69808672 Show fit | 2.69 |
ENSMUST00000036074.8
ENSMUST00000123453.1 |
Gem-interacting protein |
|
| chr13_-_19619820 Show fit | 2.69 |
ENSMUST00000002885.6
|
ependymin related protein 1 (zebrafish) |
|
| chr17_-_32403551 Show fit | 2.55 |
ENSMUST00000135618.1
ENSMUST00000063824.7 |
RAS protein activator like 3 |
|
| chr2_+_118598209 Show fit | 2.53 |
ENSMUST00000038341.7
|
budding uninhibited by benzimidazoles 1 homolog, beta (S. cerevisiae) |
Network of associatons between targets according to the STRING database.
First level regulatory network of Erg
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.9 | 8.2 | GO:0033227 | dsRNA transport(GO:0033227) |
| 0.1 | 5.3 | GO:0000038 | very long-chain fatty acid metabolic process(GO:0000038) |
| 1.0 | 5.0 | GO:0051140 | regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142) |
| 0.9 | 4.6 | GO:1903527 | positive regulation of membrane tubulation(GO:1903527) |
| 0.7 | 3.7 | GO:0060023 | soft palate development(GO:0060023) |
| 0.6 | 3.3 | GO:0097210 | response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211) |
| 0.0 | 3.3 | GO:0042254 | ribosome biogenesis(GO:0042254) |
| 0.8 | 2.5 | GO:0051754 | meiotic sister chromatid cohesion, centromeric(GO:0051754) |
| 0.1 | 2.5 | GO:0033235 | positive regulation of protein sumoylation(GO:0033235) |
| 0.2 | 2.4 | GO:0048752 | semicircular canal morphogenesis(GO:0048752) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 5.9 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
| 0.1 | 5.6 | GO:0005581 | collagen trimer(GO:0005581) |
| 0.3 | 5.0 | GO:0031235 | intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235) |
| 0.4 | 4.6 | GO:0005862 | muscle thin filament tropomyosin(GO:0005862) |
| 0.0 | 3.9 | GO:0032432 | actin filament bundle(GO:0032432) |
| 0.0 | 3.8 | GO:0005741 | mitochondrial outer membrane(GO:0005741) |
| 0.1 | 3.3 | GO:0031307 | integral component of mitochondrial outer membrane(GO:0031307) |
| 0.1 | 3.3 | GO:0002102 | podosome(GO:0002102) |
| 0.0 | 3.2 | GO:0005777 | peroxisome(GO:0005777) microbody(GO:0042579) |
| 0.1 | 3.0 | GO:0022627 | cytosolic small ribosomal subunit(GO:0022627) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 14.4 | GO:0005096 | GTPase activator activity(GO:0005096) |
| 1.4 | 8.2 | GO:0051033 | nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033) |
| 0.0 | 7.8 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
| 0.1 | 5.4 | GO:0008307 | structural constituent of muscle(GO:0008307) |
| 0.1 | 5.2 | GO:0001786 | phosphatidylserine binding(GO:0001786) |
| 0.3 | 4.5 | GO:0031957 | very long-chain fatty acid-CoA ligase activity(GO:0031957) |
| 0.1 | 4.5 | GO:0005201 | extracellular matrix structural constituent(GO:0005201) |
| 0.4 | 3.4 | GO:0004908 | interleukin-1 receptor activity(GO:0004908) |
| 0.0 | 2.6 | GO:0051015 | actin filament binding(GO:0051015) |
| 0.4 | 2.4 | GO:0010997 | anaphase-promoting complex binding(GO:0010997) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 5.6 | PID INTEGRIN1 PATHWAY | Beta1 integrin cell surface interactions |
| 0.1 | 4.9 | PID PLK1 PATHWAY | PLK1 signaling events |
| 0.1 | 4.9 | PID ILK PATHWAY | Integrin-linked kinase signaling |
| 0.1 | 4.5 | PID ARF 3PATHWAY | Arf1 pathway |
| 0.0 | 4.5 | NABA ECM GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
| 0.1 | 3.8 | PID IL12 STAT4 PATHWAY | IL12 signaling mediated by STAT4 |
| 0.0 | 2.6 | PID AP1 PATHWAY | AP-1 transcription factor network |
| 0.1 | 2.1 | PID AURORA B PATHWAY | Aurora B signaling |
| 0.0 | 2.0 | PID RHOA REG PATHWAY | Regulation of RhoA activity |
| 0.1 | 1.7 | PID INTEGRIN4 PATHWAY | Alpha6 beta4 integrin-ligand interactions |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 7.5 | REACTOME PEPTIDE CHAIN ELONGATION | Genes involved in Peptide chain elongation |
| 0.0 | 6.5 | REACTOME SIGNALING BY RHO GTPASES | Genes involved in Signaling by Rho GTPases |
| 0.1 | 5.9 | REACTOME SMOOTH MUSCLE CONTRACTION | Genes involved in Smooth Muscle Contraction |
| 0.1 | 3.7 | REACTOME COLLAGEN FORMATION | Genes involved in Collagen formation |
| 0.1 | 2.6 | REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS | Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components |
| 0.0 | 2.5 | REACTOME INWARDLY RECTIFYING K CHANNELS | Genes involved in Inwardly rectifying K+ channels |
| 0.1 | 2.2 | REACTOME REGULATION OF GLUCOKINASE BY GLUCOKINASE REGULATORY PROTEIN | Genes involved in Regulation of Glucokinase by Glucokinase Regulatory Protein |
| 0.0 | 2.2 | REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL | Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell |
| 0.1 | 1.6 | REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS | Genes involved in Synthesis of very long-chain fatty acyl-CoAs |
| 0.0 | 1.6 | REACTOME MITOCHONDRIAL PROTEIN IMPORT | Genes involved in Mitochondrial Protein Import |