Project
12D miR HR13_24
Navigation
Downloads
Results for Etv1_Etv5_Gabpa
Z-value: 3.31
Motif logo
Transcription factors associated with Etv1_Etv5_Gabpa
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Gabpa | mm10_v2_chr16_+_84835070_84835124 | 0.96 | 2.7e-06 | Click! |
| Etv1 | mm10_v2_chr12_+_38783503_38783527 | 0.96 | 4.5e-06 | Click! |
| Etv5 | mm10_v2_chr16_-_22439719_22439733 | -0.90 | 1.4e-04 | Click! |
Network of associatons between targets according to the STRING database.
First level regulatory network of Etv1_Etv5_Gabpa
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.9 | 70.7 | GO:0042273 | ribosomal large subunit biogenesis(GO:0042273) |
| 0.3 | 38.4 | GO:0042254 | ribosome biogenesis(GO:0042254) |
| 0.1 | 31.5 | GO:0000398 | RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398) |
| 1.6 | 28.0 | GO:0051988 | regulation of attachment of spindle microtubules to kinetochore(GO:0051988) |
| 0.7 | 25.9 | GO:0060236 | regulation of mitotic spindle organization(GO:0060236) |
| 0.1 | 22.3 | GO:0006412 | translation(GO:0006412) |
| 0.2 | 21.1 | GO:0006413 | translational initiation(GO:0006413) |
| 0.5 | 18.8 | GO:0000387 | spliceosomal snRNP assembly(GO:0000387) |
| 1.0 | 18.4 | GO:0006744 | ubiquinone biosynthetic process(GO:0006744) |
| 0.2 | 17.3 | GO:0008033 | tRNA processing(GO:0008033) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 110.6 | GO:0005730 | nucleolus(GO:0005730) |
| 0.8 | 61.9 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
| 0.8 | 41.4 | GO:0022627 | cytosolic small ribosomal subunit(GO:0022627) |
| 1.0 | 32.5 | GO:0030687 | preribosome, large subunit precursor(GO:0030687) |
| 0.7 | 24.9 | GO:0035371 | microtubule plus-end(GO:0035371) |
| 0.5 | 22.2 | GO:0009295 | nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645) |
| 0.8 | 20.3 | GO:0030686 | 90S preribosome(GO:0030686) |
| 1.1 | 20.1 | GO:0031616 | spindle pole centrosome(GO:0031616) |
| 0.3 | 19.3 | GO:0071013 | catalytic step 2 spliceosome(GO:0071013) |
| 1.5 | 18.6 | GO:0005687 | U4 snRNP(GO:0005687) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 101.8 | GO:0003723 | RNA binding(GO:0003723) |
| 0.5 | 67.9 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
| 0.6 | 33.1 | GO:0019843 | rRNA binding(GO:0019843) |
| 0.5 | 31.5 | GO:0003743 | translation initiation factor activity(GO:0003743) |
| 1.3 | 18.2 | GO:0003688 | DNA replication origin binding(GO:0003688) |
| 0.6 | 17.7 | GO:0070182 | DNA polymerase binding(GO:0070182) |
| 1.9 | 17.3 | GO:1990446 | U1 snRNP binding(GO:1990446) |
| 0.2 | 16.4 | GO:0003777 | microtubule motor activity(GO:0003777) |
| 0.1 | 16.0 | GO:0005096 | GTPase activator activity(GO:0005096) |
| 0.6 | 15.6 | GO:0008569 | ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.7 | 30.3 | PID AURORA A PATHWAY | Aurora A signaling |
| 0.6 | 27.7 | PID ATR PATHWAY | ATR signaling pathway |
| 0.5 | 21.1 | PID AURORA B PATHWAY | Aurora B signaling |
| 0.2 | 19.2 | PID MYC ACTIV PATHWAY | Validated targets of C-MYC transcriptional activation |
| 0.5 | 15.4 | PID FANCONI PATHWAY | Fanconi anemia pathway |
| 0.3 | 11.4 | PID FOXM1 PATHWAY | FOXM1 transcription factor network |
| 0.1 | 11.4 | PID CDC42 PATHWAY | CDC42 signaling events |
| 0.1 | 8.5 | PID ECADHERIN NASCENT AJ PATHWAY | E-cadherin signaling in the nascent adherens junction |
| 0.1 | 5.6 | NABA COLLAGENS | Genes encoding collagen proteins |
| 0.1 | 4.7 | ST TUMOR NECROSIS FACTOR PATHWAY | Tumor Necrosis Factor Pathway. |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.9 | 47.9 | REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX | Genes involved in Formation of the ternary complex, and subsequently, the 43S complex |
| 0.7 | 46.2 | REACTOME PEPTIDE CHAIN ELONGATION | Genes involved in Peptide chain elongation |
| 0.3 | 29.2 | REACTOME MITOTIC PROMETAPHASE | Genes involved in Mitotic Prometaphase |
| 0.8 | 26.9 | REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY | Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery |
| 0.8 | 21.7 | REACTOME KINESINS | Genes involved in Kinesins |
| 0.1 | 21.6 | REACTOME SIGNALING BY RHO GTPASES | Genes involved in Signaling by Rho GTPases |
| 1.3 | 20.8 | REACTOME UNWINDING OF DNA | Genes involved in Unwinding of DNA |
| 0.4 | 20.4 | REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6 | Genes involved in CDK-mediated phosphorylation and removal of Cdc6 |
| 1.4 | 17.3 | REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS | Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs |
| 0.2 | 15.7 | REACTOME RESPIRATORY ELECTRON TRANSPORT | Genes involved in Respiratory electron transport |