Project
12D miR HR13_24
Navigation
Downloads
Results for Hnf4a
Z-value: 2.29
Motif logo
Transcription factors associated with Hnf4a
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Hnf4a | mm10_v2_chr2_+_163547148_163547188 | -0.29 | 3.8e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr3_+_122895072 Show fit | 10.43 |
ENSMUST00000023820.5
|
fatty acid binding protein 2, intestinal |
|
| chr9_+_46240696 Show fit | 5.69 |
ENSMUST00000034585.6
|
apolipoprotein A-IV |
|
| chr1_-_87101590 Show fit | 4.61 |
ENSMUST00000113270.2
|
alkaline phosphatase, intestinal |
|
| chr18_+_21072329 Show fit | 4.46 |
ENSMUST00000082235.4
|
meprin 1 beta |
|
| chr11_+_115877497 Show fit | 4.29 |
ENSMUST00000144032.1
|
myosin XVB |
|
| chr11_+_70505244 Show fit | 3.70 |
ENSMUST00000019063.2
|
transmembrane 4 superfamily member 5 |
|
| chr16_+_33794345 Show fit | 3.68 |
ENSMUST00000023520.6
|
mucin 13, epithelial transmembrane |
|
| chr16_+_33794008 Show fit | 3.67 |
ENSMUST00000115044.1
|
mucin 13, epithelial transmembrane |
|
| chr12_+_7977640 Show fit | 3.53 |
ENSMUST00000171271.1
ENSMUST00000037811.6 ENSMUST00000037520.7 |
apolipoprotein B |
|
| chr6_+_71199827 Show fit | 3.42 |
ENSMUST00000067492.7
|
fatty acid binding protein 1, liver |
Network of associatons between targets according to the STRING database.
First level regulatory network of Hnf4a
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 13.1 | GO:0050892 | intestinal absorption(GO:0050892) |
| 0.6 | 9.1 | GO:0019373 | epoxygenase P450 pathway(GO:0019373) |
| 0.5 | 7.4 | GO:0030277 | maintenance of gastrointestinal epithelium(GO:0030277) |
| 1.9 | 5.7 | GO:0034443 | regulation of lipoprotein oxidation(GO:0034442) negative regulation of lipoprotein oxidation(GO:0034443) multicellular organism lipid catabolic process(GO:0044240) |
| 0.0 | 4.7 | GO:0071772 | response to BMP(GO:0071772) cellular response to BMP stimulus(GO:0071773) |
| 0.1 | 4.5 | GO:1901998 | toxin transport(GO:1901998) |
| 0.7 | 4.3 | GO:0010915 | regulation of very-low-density lipoprotein particle clearance(GO:0010915) negative regulation of very-low-density lipoprotein particle clearance(GO:0010916) |
| 0.4 | 3.5 | GO:0006642 | triglyceride mobilization(GO:0006642) |
| 0.5 | 3.1 | GO:0014826 | regulation of systemic arterial blood pressure by endothelin(GO:0003100) vein smooth muscle contraction(GO:0014826) |
| 0.1 | 2.9 | GO:0019369 | arachidonic acid metabolic process(GO:0019369) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 1.0 | 13.9 | GO:0045179 | apical cortex(GO:0045179) |
| 0.8 | 13.8 | GO:0042627 | chylomicron(GO:0042627) |
| 0.0 | 6.2 | GO:0016324 | apical plasma membrane(GO:0016324) |
| 0.0 | 6.0 | GO:0005903 | brush border(GO:0005903) |
| 0.0 | 5.5 | GO:0009897 | external side of plasma membrane(GO:0009897) |
| 0.0 | 2.2 | GO:0005814 | centriole(GO:0005814) |
| 0.1 | 2.0 | GO:0030140 | trans-Golgi network transport vesicle(GO:0030140) |
| 0.0 | 2.0 | GO:0005811 | lipid particle(GO:0005811) |
| 0.1 | 1.7 | GO:0036056 | filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057) |
| 0.2 | 1.3 | GO:0045098 | type III intermediate filament(GO:0045098) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 2.1 | 14.6 | GO:0005324 | long-chain fatty acid transporter activity(GO:0005324) |
| 2.1 | 6.4 | GO:0033695 | oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875) |
| 1.0 | 5.9 | GO:0060228 | phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228) |
| 0.0 | 5.0 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
| 0.7 | 4.6 | GO:0004035 | alkaline phosphatase activity(GO:0004035) |
| 0.3 | 4.0 | GO:0070330 | aromatase activity(GO:0070330) |
| 0.4 | 3.5 | GO:0035473 | lipase binding(GO:0035473) |
| 0.8 | 3.1 | GO:0031708 | endothelin B receptor binding(GO:0031708) |
| 0.9 | 2.6 | GO:0060230 | lipoprotein lipase activator activity(GO:0060230) |
| 0.0 | 2.6 | GO:0004553 | hydrolase activity, hydrolyzing O-glycosyl compounds(GO:0004553) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 5.8 | NABA ECM AFFILIATED | Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins |
| 0.1 | 4.5 | PID AJDISS 2PATHWAY | Posttranslational regulation of adherens junction stability and dissassembly |
| 0.1 | 3.3 | PID AMB2 NEUTROPHILS PATHWAY | amb2 Integrin signaling |
| 0.0 | 3.1 | PID HNF3B PATHWAY | FOXA2 and FOXA3 transcription factor networks |
| 0.0 | 3.1 | PID ENDOTHELIN PATHWAY | Endothelins |
| 0.0 | 1.6 | PID REG GR PATHWAY | Glucocorticoid receptor regulatory network |
| 0.1 | 1.4 | PID ARF6 DOWNSTREAM PATHWAY | Arf6 downstream pathway |
| 0.0 | 1.4 | PID RHOA REG PATHWAY | Regulation of RhoA activity |
| 0.0 | 1.2 | PID PTP1B PATHWAY | Signaling events mediated by PTP1B |
| 0.0 | 0.8 | PID P38 MKK3 6PATHWAY | p38 MAPK signaling pathway |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 8.1 | REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT | Genes involved in Chylomicron-mediated lipid transport |
| 0.4 | 7.4 | REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS | Genes involved in Termination of O-glycan biosynthesis |
| 0.3 | 4.4 | REACTOME PYRIMIDINE CATABOLISM | Genes involved in Pyrimidine catabolism |
| 0.0 | 3.9 | REACTOME PEPTIDE LIGAND BINDING RECEPTORS | Genes involved in Peptide ligand-binding receptors |
| 0.0 | 3.0 | REACTOME PPARA ACTIVATES GENE EXPRESSION | Genes involved in PPARA Activates Gene Expression |
| 0.9 | 2.6 | REACTOME DIGESTION OF DIETARY CARBOHYDRATE | Genes involved in Digestion of dietary carbohydrate |
| 0.2 | 2.5 | REACTOME ABACAVIR TRANSPORT AND METABOLISM | Genes involved in Abacavir transport and metabolism |
| 0.1 | 1.6 | REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN | Genes involved in Platelet Adhesion to exposed collagen |
| 0.0 | 1.4 | REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION | Genes involved in Pre-NOTCH Transcription and Translation |
| 0.0 | 1.4 | REACTOME G ALPHA Q SIGNALLING EVENTS | Genes involved in G alpha (q) signalling events |