Project
12D miR HR13_24
Navigation
Downloads
Results for Sox5_Sry
Z-value: 1.72
Motif logo
Transcription factors associated with Sox5_Sry
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Sox5 | mm10_v2_chr6_-_143947092_143947111 | 0.76 | 6.7e-03 | Click! |
Network of associatons between targets according to the STRING database.
First level regulatory network of Sox5_Sry
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.7 | 7.6 | GO:2000980 | regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980) |
| 0.9 | 7.4 | GO:0090074 | negative regulation of protein homodimerization activity(GO:0090074) |
| 2.2 | 6.7 | GO:0030824 | negative regulation of cGMP metabolic process(GO:0030824) negative regulation of cGMP biosynthetic process(GO:0030827) negative regulation of guanylate cyclase activity(GO:0031283) |
| 0.2 | 5.2 | GO:0050650 | chondroitin sulfate proteoglycan biosynthetic process(GO:0050650) |
| 0.8 | 5.0 | GO:0042276 | error-prone translesion synthesis(GO:0042276) |
| 0.5 | 4.6 | GO:0010587 | miRNA catabolic process(GO:0010587) |
| 0.6 | 4.4 | GO:0042320 | negative regulation of synaptic transmission, dopaminergic(GO:0032227) regulation of circadian sleep/wake cycle, REM sleep(GO:0042320) circadian sleep/wake cycle, REM sleep(GO:0042747) |
| 0.1 | 3.3 | GO:0048745 | smooth muscle tissue development(GO:0048745) |
| 0.3 | 3.1 | GO:0006268 | DNA unwinding involved in DNA replication(GO:0006268) |
| 1.0 | 3.0 | GO:0042271 | unidimensional cell growth(GO:0009826) susceptibility to natural killer cell mediated cytotoxicity(GO:0042271) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 8.0 | GO:0005815 | microtubule organizing center(GO:0005815) |
| 0.0 | 7.9 | GO:0000139 | Golgi membrane(GO:0000139) |
| 0.5 | 6.7 | GO:0044327 | dendritic spine head(GO:0044327) |
| 0.8 | 5.0 | GO:0016035 | zeta DNA polymerase complex(GO:0016035) |
| 0.0 | 3.3 | GO:0090575 | RNA polymerase II transcription factor complex(GO:0090575) |
| 0.2 | 3.1 | GO:0042555 | MCM complex(GO:0042555) |
| 0.2 | 3.0 | GO:0070852 | cell body fiber(GO:0070852) |
| 0.0 | 2.8 | GO:0032420 | stereocilium(GO:0032420) |
| 0.1 | 2.5 | GO:0014731 | spectrin-associated cytoskeleton(GO:0014731) |
| 0.0 | 2.5 | GO:0017053 | transcriptional repressor complex(GO:0017053) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 7.4 | GO:0016810 | hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds(GO:0016810) |
| 0.5 | 7.2 | GO:0048273 | mitogen-activated protein kinase p38 binding(GO:0048273) |
| 0.0 | 7.0 | GO:0005509 | calcium ion binding(GO:0005509) |
| 0.9 | 5.3 | GO:0015018 | galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018) |
| 0.2 | 4.4 | GO:0071855 | neuropeptide receptor binding(GO:0071855) |
| 0.1 | 3.1 | GO:0004003 | ATP-dependent DNA helicase activity(GO:0004003) |
| 0.0 | 2.6 | GO:0005200 | structural constituent of cytoskeleton(GO:0005200) |
| 0.0 | 2.6 | GO:0001158 | enhancer sequence-specific DNA binding(GO:0001158) |
| 0.6 | 2.5 | GO:0047288 | beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836) monosialoganglioside sialyltransferase activity(GO:0047288) |
| 0.0 | 2.4 | GO:0051117 | ATPase binding(GO:0051117) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 8.0 | PID ARF6 TRAFFICKING PATHWAY | Arf6 trafficking events |
| 0.1 | 5.3 | PID ATR PATHWAY | ATR signaling pathway |
| 0.0 | 4.6 | PID AR PATHWAY | Coregulation of Androgen receptor activity |
| 0.0 | 3.6 | PID TAP63 PATHWAY | Validated transcriptional targets of TAp63 isoforms |
| 0.0 | 2.8 | PID MYC ACTIV PATHWAY | Validated targets of C-MYC transcriptional activation |
| 0.0 | 2.7 | PID PDGFRB PATHWAY | PDGFR-beta signaling pathway |
| 0.0 | 2.4 | NABA ECM GLYCOPROTEINS | Genes encoding structural ECM glycoproteins |
| 0.1 | 2.3 | PID ANTHRAX PATHWAY | Cellular roles of Anthrax toxin |
| 0.0 | 1.4 | PID HDAC CLASSII PATHWAY | Signaling events mediated by HDAC Class II |
| 0.0 | 1.3 | NABA COLLAGENS | Genes encoding collagen proteins |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 6.4 | REACTOME CRMPS IN SEMA3A SIGNALING | Genes involved in CRMPs in Sema3A signaling |
| 0.2 | 6.0 | REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS | Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis |
| 0.0 | 4.4 | REACTOME PEPTIDE LIGAND BINDING RECEPTORS | Genes involved in Peptide ligand-binding receptors |
| 0.2 | 3.1 | REACTOME UNWINDING OF DNA | Genes involved in Unwinding of DNA |
| 0.1 | 2.6 | REACTOME SMOOTH MUSCLE CONTRACTION | Genes involved in Smooth Muscle Contraction |
| 0.1 | 2.5 | REACTOME ACTIVATION OF BH3 ONLY PROTEINS | Genes involved in Activation of BH3-only proteins |
| 0.1 | 2.5 | REACTOME MYOGENESIS | Genes involved in Myogenesis |
| 0.1 | 2.5 | REACTOME INTERACTION BETWEEN L1 AND ANKYRINS | Genes involved in Interaction between L1 and Ankyrins |
| 0.0 | 2.4 | REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION | Genes involved in Factors involved in megakaryocyte development and platelet production |
| 0.1 | 2.2 | REACTOME ADHERENS JUNCTIONS INTERACTIONS | Genes involved in Adherens junctions interactions |