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GFI1 WT vs 36n/n vs KD

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Results for Foxd2

Z-value: 1.26

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Transcription factors associated with Foxd2

Gene Symbol Gene ID Gene Info
Foxd2
ENSMUSG00000055210.5 forkhead box D2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Foxd2mm39_v1_chr4_-_114766070_1147661110.875.3e-02Click!

Activity profile of Foxd2 motif

Sorted Z-values of Foxd2 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr13_+_23715220 3.66 ENSMUST00000102972.6
H4c8
H4 clustered histone 8
chr1_+_107456731 2.24 ENSMUST00000182198.8
Serpinb10
serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 10
chr9_+_37995368 1.48 ENSMUST00000212502.4
Olfr887
olfactory receptor 887
chr7_-_103113358 1.47 ENSMUST00000214347.2
Olfr607
olfactory receptor 607
chr16_-_16345197 1.27 ENSMUST00000069284.14
Fgd4
FYVE, RhoGEF and PH domain containing 4
chr1_+_172525613 1.25 ENSMUST00000038495.5
Crp
C-reactive protein, pentraxin-related
chr2_-_111779785 1.25 ENSMUST00000099604.6
Olfr1307
olfactory receptor 1307
chr7_+_28834276 1.15 ENSMUST00000161522.8
ENSMUST00000204845.3
ENSMUST00000205027.3
ENSMUST00000204194.3
ENSMUST00000203070.3
ENSMUST00000203380.3
Rasgrp4
RAS guanyl releasing protein 4
chr2_-_172782089 1.08 ENSMUST00000009143.8
Bmp7
bone morphogenetic protein 7
chr16_-_4698148 1.02 ENSMUST00000037843.7
Ubald1
UBA-like domain containing 1
chr10_+_66932235 1.00 ENSMUST00000174317.8
Jmjd1c
jumonji domain containing 1C
chr4_+_115594951 0.94 ENSMUST00000106522.9
Efcab14
EF-hand calcium binding domain 14
chrM_-_14061 0.94 ENSMUST00000082419.1
mt-Nd6
mitochondrially encoded NADH dehydrogenase 6
chr10_+_129320621 0.90 ENSMUST00000213236.2
ENSMUST00000213992.2
Olfr789
olfactory receptor 789
chr16_-_58620631 0.89 ENSMUST00000206205.3
Olfr173
olfactory receptor 173
chr6_-_131224305 0.85 ENSMUST00000032306.15
ENSMUST00000088867.7
Klra2
killer cell lectin-like receptor, subfamily A, member 2
chr2_-_87868043 0.84 ENSMUST00000129056.3
Olfr73
olfactory receptor 73
chr12_-_103597663 0.82 ENSMUST00000121625.2
ENSMUST00000044231.12
Serpina10
serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
chr10_+_93324624 0.80 ENSMUST00000129421.8
Hal
histidine ammonia lyase
chrX_-_156198282 0.78 ENSMUST00000079945.11
ENSMUST00000138396.3
Phex
phosphate regulating endopeptidase homolog, X-linked
chr5_-_23889607 0.76 ENSMUST00000197985.5
Srpk2
serine/arginine-rich protein specific kinase 2
chr6_-_57992144 0.67 ENSMUST00000228070.2
ENSMUST00000228040.2
Vmn1r26
vomeronasal 1 receptor 26
chr2_-_45000389 0.67 ENSMUST00000201804.4
ENSMUST00000028229.13
ENSMUST00000202187.4
ENSMUST00000153561.6
ENSMUST00000201490.2
Zeb2
zinc finger E-box binding homeobox 2
chr7_-_85065128 0.67 ENSMUST00000171213.3
ENSMUST00000233336.2
Vmn2r69
vomeronasal 2, receptor 69
chr18_-_60724855 0.66 ENSMUST00000056533.9
Myoz3
myozenin 3
chr19_-_31742427 0.65 ENSMUST00000065067.14
Prkg1
protein kinase, cGMP-dependent, type I
chr10_-_89457115 0.64 ENSMUST00000020102.14
Slc17a8
solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 8
chr4_+_115594918 0.64 ENSMUST00000106525.9
Efcab14
EF-hand calcium binding domain 14
chr11_+_29413734 0.64 ENSMUST00000155854.8
Ccdc88a
coiled coil domain containing 88A
chr14_+_50656083 0.60 ENSMUST00000216949.2
Olfr739
olfactory receptor 739
chr15_+_3300249 0.60 ENSMUST00000082424.12
ENSMUST00000159158.9
ENSMUST00000159216.10
ENSMUST00000160311.3
Selenop
selenoprotein P
chr2_-_87798643 0.56 ENSMUST00000099841.4
Olfr1157
olfactory receptor 1157
chr7_+_6346723 0.53 ENSMUST00000207173.3
Gm3854
predicted gene 3854
chr2_+_87216193 0.47 ENSMUST00000215371.2
Olfr1122
olfactory receptor 1122
chr13_+_41040657 0.46 ENSMUST00000069958.15
Gcnt2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme
chr7_+_97480125 0.43 ENSMUST00000206351.2
Pak1
p21 (RAC1) activated kinase 1
chr2_+_24235300 0.42 ENSMUST00000114485.9
ENSMUST00000114482.3
Il1rn
interleukin 1 receptor antagonist
chr17_-_56583715 0.42 ENSMUST00000058136.9
Ticam1
toll-like receptor adaptor molecule 1
chr2_-_45001141 0.40 ENSMUST00000201969.4
ENSMUST00000201623.4
Zeb2
zinc finger E-box binding homeobox 2
chr12_-_110807330 0.40 ENSMUST00000177224.2
ENSMUST00000084974.11
ENSMUST00000070565.15
Mok
MOK protein kinase
chr2_+_87853118 0.39 ENSMUST00000214438.2
Olfr1161
olfactory receptor 1161
chr13_-_97235745 0.38 ENSMUST00000071118.7
Gm6169
predicted gene 6169
chr11_-_34048538 0.38 ENSMUST00000223852.2
4930469K13Rik
RIKEN cDNA 4930469K13 gene
chrX_-_104972938 0.37 ENSMUST00000198448.5
ENSMUST00000199233.5
ENSMUST00000134507.8
ENSMUST00000154866.8
ENSMUST00000128968.8
ENSMUST00000134381.8
ENSMUST00000150914.8
Atrx
ATRX, chromatin remodeler
chr10_+_34265969 0.36 ENSMUST00000105511.2
Col10a1
collagen, type X, alpha 1
chr1_-_80687213 0.34 ENSMUST00000186087.7
Dock10
dedicator of cytokinesis 10
chr14_+_50741057 0.33 ENSMUST00000217437.2
ENSMUST00000213935.2
Olfr742
olfactory receptor 742
chr19_+_26725589 0.31 ENSMUST00000207812.2
ENSMUST00000175791.9
ENSMUST00000207118.2
ENSMUST00000209085.2
ENSMUST00000112637.10
ENSMUST00000207054.2
ENSMUST00000208589.2
ENSMUST00000176475.9
ENSMUST00000176698.9
ENSMUST00000207832.2
ENSMUST00000177252.9
ENSMUST00000208712.2
ENSMUST00000208186.2
ENSMUST00000208806.2
ENSMUST00000208027.2
Smarca2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr10_-_128579879 0.30 ENSMUST00000026414.9
Dgka
diacylglycerol kinase, alpha
chr9_-_95632387 0.30 ENSMUST00000189137.7
ENSMUST00000053785.10
Trpc1
transient receptor potential cation channel, subfamily C, member 1
chr9_+_38340751 0.29 ENSMUST00000216502.3
ENSMUST00000216644.2
Olfr901
olfactory receptor 901
chr2_-_73143045 0.29 ENSMUST00000058615.10
Cir1
corepressor interacting with RBPJ, 1
chr2_-_86008164 0.28 ENSMUST00000215171.2
Olfr1044
olfactory receptor 1044
chr6_-_119925387 0.28 ENSMUST00000162541.8
Wnk1
WNK lysine deficient protein kinase 1
chr9_+_78016468 0.28 ENSMUST00000118869.8
ENSMUST00000125615.2
Cilk1
ciliogenesis associated kinase 1
chr17_+_34311314 0.27 ENSMUST00000025192.8
H2-Oa
histocompatibility 2, O region alpha locus
chr15_+_99291491 0.27 ENSMUST00000159531.3
Tmbim6
transmembrane BAX inhibitor motif containing 6
chr7_+_43284131 0.27 ENSMUST00000032663.10
Ceacam18
carcinoembryonic antigen-related cell adhesion molecule 18
chr2_-_86061745 0.25 ENSMUST00000216056.2
Olfr1047
olfactory receptor 1047
chr9_+_38725910 0.23 ENSMUST00000213164.2
Olfr922
olfactory receptor 922
chr5_-_86475595 0.23 ENSMUST00000122377.2
Tmprss11d
transmembrane protease, serine 11d
chr7_-_34012934 0.23 ENSMUST00000206399.2
Garre1
granule associated Rac and RHOG effector 1
chr6_+_13069757 0.23 ENSMUST00000124234.8
ENSMUST00000142211.8
ENSMUST00000031556.14
Tmem106b
transmembrane protein 106B
chr7_-_34012956 0.23 ENSMUST00000108074.8
Garre1
granule associated Rac and RHOG effector 1
chr11_+_58549642 0.22 ENSMUST00000214392.2
Olfr322
olfactory receptor 322
chr14_-_75368321 0.22 ENSMUST00000022574.5
Lrrc63
leucine rich repeat containing 63
chr2_-_125624754 0.22 ENSMUST00000053699.13
Secisbp2l
SECIS binding protein 2-like
chr11_-_75330302 0.20 ENSMUST00000043696.9
Serpinf2
serine (or cysteine) peptidase inhibitor, clade F, member 2
chr5_+_150876072 0.19 ENSMUST00000078856.8
Kl
klotho
chr10_-_95678748 0.19 ENSMUST00000210336.2
Gm33543
predicted gene, 33543
chr10_-_95678786 0.18 ENSMUST00000211096.2
Gm33543
predicted gene, 33543
chrY_-_70026134 0.18 ENSMUST00000188554.7
ENSMUST00000191151.2
Gm28079
predicted gene 28079
chr4_+_108576846 0.18 ENSMUST00000178992.2
3110021N24Rik
RIKEN cDNA 3110021N24 gene
chr13_-_95170755 0.17 ENSMUST00000162670.8
Pde8b
phosphodiesterase 8B
chr2_+_152511381 0.17 ENSMUST00000125366.8
ENSMUST00000109825.8
ENSMUST00000089059.9
ENSMUST00000079247.4
H13
histocompatibility 13
chr16_-_58583539 0.16 ENSMUST00000214139.2
Olfr172
olfactory receptor 172
chrX_+_82898974 0.16 ENSMUST00000239269.2
Dmd
dystrophin, muscular dystrophy
chr2_-_86857424 0.15 ENSMUST00000214857.2
ENSMUST00000215972.2
Olfr1104
olfactory receptor 1104
chr2_-_87881473 0.14 ENSMUST00000183862.3
Olfr1162
olfactory receptor 1162
chr6_+_136495784 0.13 ENSMUST00000032335.13
ENSMUST00000185724.7
Atf7ip
activating transcription factor 7 interacting protein
chr18_+_43340687 0.13 ENSMUST00000237797.2
Stk32a
serine/threonine kinase 32A
chrX_+_158480304 0.13 ENSMUST00000123433.8
Sh3kbp1
SH3-domain kinase binding protein 1
chr18_+_68470616 0.12 ENSMUST00000172148.4
ENSMUST00000239469.2
Mc5r
melanocortin 5 receptor
chr11_-_75330415 0.11 ENSMUST00000128330.8
Serpinf2
serine (or cysteine) peptidase inhibitor, clade F, member 2
chr14_+_80237691 0.11 ENSMUST00000228749.2
ENSMUST00000088735.4
Olfm4
olfactomedin 4
chr12_-_101924407 0.10 ENSMUST00000159883.2
ENSMUST00000160251.8
ENSMUST00000161011.8
ENSMUST00000021606.12
Atxn3
ataxin 3
chrM_+_7006 0.10 ENSMUST00000082405.1
mt-Co2
mitochondrially encoded cytochrome c oxidase II
chr14_-_70867588 0.08 ENSMUST00000228009.2
Dmtn
dematin actin binding protein
chr2_+_164674801 0.08 ENSMUST00000103092.9
ENSMUST00000151493.3
ENSMUST00000127650.8
Ctsa
cathepsin A
chr15_+_78819378 0.07 ENSMUST00000145157.2
ENSMUST00000123013.2
Nol12
nucleolar protein 12
chr5_-_23889591 0.07 ENSMUST00000198549.2
Srpk2
serine/arginine-rich protein specific kinase 2
chrX_-_49517375 0.07 ENSMUST00000215270.2
Olfr1324
olfactory receptor 1324
chr16_+_43056218 0.06 ENSMUST00000146708.8
Zbtb20
zinc finger and BTB domain containing 20
chr18_+_73996743 0.06 ENSMUST00000134847.2
Mro
maestro
chr1_-_37535170 0.05 ENSMUST00000148047.2
Mgat4a
mannoside acetylglucosaminyltransferase 4, isoenzyme A
chr5_+_107645626 0.05 ENSMUST00000152474.8
ENSMUST00000060553.8
Btbd8
BTB (POZ) domain containing 8
chr10_+_42736771 0.05 ENSMUST00000105494.8
Scml4
Scm polycomb group protein like 4
chr2_+_164674782 0.05 ENSMUST00000103093.10
Ctsa
cathepsin A
chr9_-_55190902 0.05 ENSMUST00000164721.8
Nrg4
neuregulin 4
chr1_+_171238873 0.05 ENSMUST00000159207.8
ENSMUST00000161241.8
Usf1
upstream transcription factor 1
chr10_+_57521930 0.04 ENSMUST00000177325.8
Pkib
protein kinase inhibitor beta, cAMP dependent, testis specific
chr10_+_129907079 0.04 ENSMUST00000216879.2
Olfr822
olfactory receptor 822
chr7_-_126795040 0.04 ENSMUST00000035771.5
Cd2bp2
CD2 cytoplasmic tail binding protein 2
chr18_+_89224219 0.04 ENSMUST00000236835.2
Cd226
CD226 antigen
chr5_+_87955941 0.03 ENSMUST00000072539.12
ENSMUST00000113279.8
ENSMUST00000101057.8
ENSMUST00000197301.2
Csn1s2b
casein alpha s2-like B
chr10_+_57521958 0.03 ENSMUST00000177473.8
Pkib
protein kinase inhibitor beta, cAMP dependent, testis specific
chr1_+_88334678 0.03 ENSMUST00000027518.12
Spp2
secreted phosphoprotein 2
chrX_-_104972844 0.03 ENSMUST00000198441.5
ENSMUST00000137453.8
Atrx
ATRX, chromatin remodeler
chr11_+_75541324 0.02 ENSMUST00000102505.10
Myo1c
myosin IC
chr15_-_6904450 0.02 ENSMUST00000022746.13
ENSMUST00000176826.2
Osmr
oncostatin M receptor
chr15_-_98505508 0.02 ENSMUST00000096224.6
Adcy6
adenylate cyclase 6
chr7_-_99629637 0.01 ENSMUST00000080817.6
Rnf169
ring finger protein 169
chr2_+_154042291 0.01 ENSMUST00000028987.7
Bpifb1
BPI fold containing family B, member 1
chr11_+_75890738 0.01 ENSMUST00000066408.6
1700016K19Rik
RIKEN cDNA 1700016K19 gene
chr18_+_51250748 0.01 ENSMUST00000116639.4
Prr16
proline rich 16
chrX_-_104973003 0.01 ENSMUST00000130980.2
ENSMUST00000113573.8
Atrx
ATRX, chromatin remodeler
chr7_-_132616977 0.01 ENSMUST00000169570.8
Ctbp2
C-terminal binding protein 2
chr14_+_53270305 0.01 ENSMUST00000179512.3
Trav13d-3
T cell receptor alpha variable 13D-3
chr1_+_6805048 0.01 ENSMUST00000139838.8
St18
suppression of tumorigenicity 18
chr7_+_67305162 0.01 ENSMUST00000107470.2
Ttc23
tetratricopeptide repeat domain 23
chr10_-_130050272 0.01 ENSMUST00000213568.2
Olfr827
olfactory receptor 827
chr14_+_53574579 0.01 ENSMUST00000179580.3
Trav13n-3
T cell receptor alpha variable 13N-3
chr6_-_21851827 0.01 ENSMUST00000202353.2
ENSMUST00000134635.2
ENSMUST00000123116.8
ENSMUST00000120965.8
ENSMUST00000143531.2
Tspan12
tetraspanin 12
chr5_-_103247920 0.00 ENSMUST00000112848.8
Mapk10
mitogen-activated protein kinase 10
chr2_-_104241358 0.00 ENSMUST00000230671.2
D430041D05Rik
RIKEN cDNA D430041D05 gene
chr17_-_37334091 0.00 ENSMUST00000167275.3
Mog
myelin oligodendrocyte glycoprotein
chr2_+_14393127 0.00 ENSMUST00000114731.8
ENSMUST00000082290.8
Slc39a12
solute carrier family 39 (zinc transporter), member 12
chr3_-_95310106 0.00 ENSMUST00000196239.2
4930558C23Rik
RIKEN cDNA 4930558C23 gene
chr7_+_99384352 0.00 ENSMUST00000098264.2
Olfr520
olfactory receptor 520

Network of associatons between targets according to the STRING database.

First level regulatory network of Foxd2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0072076 hyaluranon cable assembly(GO:0036118) nephrogenic mesenchyme development(GO:0072076) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.2 0.8 GO:0006548 histidine catabolic process(GO:0006548)
0.2 1.3 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.2 1.1 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.1 1.3 GO:0030035 microspike assembly(GO:0030035)
0.1 0.8 GO:0035063 nuclear speck organization(GO:0035063)
0.1 0.6 GO:1902606 regulation of large conductance calcium-activated potassium channel activity(GO:1902606) positive regulation of large conductance calcium-activated potassium channel activity(GO:1902608) regulation of testosterone biosynthetic process(GO:2000224)
0.1 0.4 GO:0061534 gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
0.1 0.6 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.1 0.4 GO:0035666 TRIF-dependent toll-like receptor signaling pathway(GO:0035666)
0.1 1.0 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.1 0.3 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581)
0.1 0.4 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.1 0.6 GO:0001887 selenium compound metabolic process(GO:0001887)
0.1 0.3 GO:0023016 signal transduction by trans-phosphorylation(GO:0023016)
0.1 0.4 GO:0035127 post-embryonic appendage morphogenesis(GO:0035120) post-embryonic limb morphogenesis(GO:0035127) post-embryonic forelimb morphogenesis(GO:0035128) telomeric repeat-containing RNA transcription(GO:0097393) telomeric repeat-containing RNA transcription from RNA pol II promoter(GO:0097394) regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901580) negative regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901581) positive regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901582)
0.1 0.5 GO:0036438 maintenance of lens transparency(GO:0036438)
0.1 0.2 GO:1904211 membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211)
0.1 0.2 GO:0021629 olfactory nerve morphogenesis(GO:0021627) olfactory nerve structural organization(GO:0021629)
0.0 0.3 GO:0010757 regulation of blood vessel size by renin-angiotensin(GO:0002034) renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure(GO:0003072) negative regulation of plasminogen activation(GO:0010757) negative regulation of fibrinolysis(GO:0051918)
0.0 0.3 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.0 0.1 GO:1904715 negative regulation of chaperone-mediated autophagy(GO:1904715)
0.0 0.2 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.0 0.2 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 0.2 GO:0035106 operant conditioning(GO:0035106)
0.0 0.6 GO:0015813 L-glutamate transport(GO:0015813)
0.0 0.3 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.0 0.3 GO:0046541 saliva secretion(GO:0046541)
0.0 0.2 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.0 0.1 GO:0035585 calcium-mediated signaling using extracellular calcium source(GO:0035585)
0.0 1.2 GO:0046579 positive regulation of Ras protein signal transduction(GO:0046579)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0097441 basilar dendrite(GO:0097441)
0.1 0.4 GO:1990707 subtelomeric heterochromatin(GO:1990421) nuclear subtelomeric heterochromatin(GO:1990707)
0.0 0.4 GO:0097342 ripoptosome(GO:0097342)
0.0 0.3 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.2 GO:0071458 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.0 0.3 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.4 GO:0071437 invadopodium(GO:0071437)
0.0 2.4 GO:0030175 filopodium(GO:0030175)
0.0 0.3 GO:0071564 npBAF complex(GO:0071564)
0.0 0.1 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.0 1.0 GO:0070469 respiratory chain(GO:0070469)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.3 GO:0001849 complement component C1q binding(GO:0001849)
0.1 0.7 GO:0051373 FATZ binding(GO:0051373)
0.1 0.5 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.1 0.8 GO:0016841 ammonia-lyase activity(GO:0016841)
0.1 0.6 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.1 0.4 GO:0005152 interleukin-1 receptor antagonist activity(GO:0005152)
0.1 1.1 GO:0070700 BMP receptor binding(GO:0070700)
0.1 0.4 GO:0015616 DNA translocase activity(GO:0015616)
0.0 0.2 GO:0004566 beta-glucuronidase activity(GO:0004566)
0.0 1.0 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.6 GO:0008430 selenium binding(GO:0008430)
0.0 0.9 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.6 GO:0005313 L-glutamate transmembrane transporter activity(GO:0005313)
0.0 1.1 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.6 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.3 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0 0.1 GO:0004977 melanocortin receptor activity(GO:0004977)
0.0 0.3 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.0 0.2 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.0 0.3 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.8 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.2 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.1 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.3 GO:0023026 MHC class II protein complex binding(GO:0023026)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 PID ALK2 PATHWAY ALK2 signaling events
0.0 1.1 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 1.2 PID RAS PATHWAY Regulation of Ras family activation
0.0 1.3 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 0.4 PID IL1 PATHWAY IL1-mediated signaling events
0.0 3.5 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.4 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 0.4 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.6 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 1.3 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK