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GFI1 WT vs 36n/n vs KD

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Results for Foxd3

Z-value: 0.45

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Transcription factors associated with Foxd3

Gene Symbol Gene ID Gene Info
Foxd3
ENSMUSG00000067261.5 forkhead box D3

Activity profile of Foxd3 motif

Sorted Z-values of Foxd3 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr13_+_23715220 1.14 ENSMUST00000102972.6
H4c8
H4 clustered histone 8
chr9_+_37995368 0.56 ENSMUST00000212502.4
Olfr887
olfactory receptor 887
chr1_+_107456731 0.53 ENSMUST00000182198.8
Serpinb10
serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 10
chr2_-_172782089 0.46 ENSMUST00000009143.8
Bmp7
bone morphogenetic protein 7
chr7_+_28834276 0.42 ENSMUST00000161522.8
ENSMUST00000204845.3
ENSMUST00000205027.3
ENSMUST00000204194.3
ENSMUST00000203070.3
ENSMUST00000203380.3
Rasgrp4
RAS guanyl releasing protein 4
chr2_-_111779785 0.36 ENSMUST00000099604.6
Olfr1307
olfactory receptor 1307
chrX_-_156198282 0.35 ENSMUST00000079945.11
ENSMUST00000138396.3
Phex
phosphate regulating endopeptidase homolog, X-linked
chr4_+_115594951 0.35 ENSMUST00000106522.9
Efcab14
EF-hand calcium binding domain 14
chr10_+_66932235 0.33 ENSMUST00000174317.8
Jmjd1c
jumonji domain containing 1C
chr16_-_4698148 0.33 ENSMUST00000037843.7
Ubald1
UBA-like domain containing 1
chr5_-_23889607 0.33 ENSMUST00000197985.5
Srpk2
serine/arginine-rich protein specific kinase 2
chr10_+_93324624 0.31 ENSMUST00000129421.8
Hal
histidine ammonia lyase
chr12_-_103597663 0.31 ENSMUST00000121625.2
ENSMUST00000044231.12
Serpina10
serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
chr10_+_129320621 0.29 ENSMUST00000213236.2
ENSMUST00000213992.2
Olfr789
olfactory receptor 789
chr4_+_115594918 0.25 ENSMUST00000106525.9
Efcab14
EF-hand calcium binding domain 14
chr10_-_89457115 0.24 ENSMUST00000020102.14
Slc17a8
solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 8
chr6_-_131224305 0.24 ENSMUST00000032306.15
ENSMUST00000088867.7
Klra2
killer cell lectin-like receptor, subfamily A, member 2
chr2_-_45000389 0.24 ENSMUST00000201804.4
ENSMUST00000028229.13
ENSMUST00000202187.4
ENSMUST00000153561.6
ENSMUST00000201490.2
Zeb2
zinc finger E-box binding homeobox 2
chr16_-_16345197 0.21 ENSMUST00000069284.14
Fgd4
FYVE, RhoGEF and PH domain containing 4
chr13_+_41040657 0.17 ENSMUST00000069958.15
Gcnt2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme
chr11_+_29413734 0.15 ENSMUST00000155854.8
Ccdc88a
coiled coil domain containing 88A
chr11_-_34048538 0.13 ENSMUST00000223852.2
4930469K13Rik
RIKEN cDNA 4930469K13 gene
chr2_-_18397547 0.13 ENSMUST00000091418.12
ENSMUST00000166495.8
Dnajc1
DnaJ heat shock protein family (Hsp40) member C1
chr2_-_45001141 0.12 ENSMUST00000201969.4
ENSMUST00000201623.4
Zeb2
zinc finger E-box binding homeobox 2
chr6_-_137548004 0.12 ENSMUST00000100841.9
Eps8
epidermal growth factor receptor pathway substrate 8
chr15_+_8997480 0.10 ENSMUST00000227191.3
Ranbp3l
RAN binding protein 3-like
chr7_+_97480125 0.08 ENSMUST00000206351.2
Pak1
p21 (RAC1) activated kinase 1
chr12_-_110807330 0.08 ENSMUST00000177224.2
ENSMUST00000084974.11
ENSMUST00000070565.15
Mok
MOK protein kinase
chr10_-_128579879 0.07 ENSMUST00000026414.9
Dgka
diacylglycerol kinase, alpha
chr11_-_75330302 0.07 ENSMUST00000043696.9
Serpinf2
serine (or cysteine) peptidase inhibitor, clade F, member 2
chr10_-_95678786 0.06 ENSMUST00000211096.2
Gm33543
predicted gene, 33543
chr15_-_98505508 0.06 ENSMUST00000096224.6
Adcy6
adenylate cyclase 6
chr10_-_95678748 0.06 ENSMUST00000210336.2
Gm33543
predicted gene, 33543
chr11_+_83193495 0.06 ENSMUST00000176430.8
ENSMUST00000065692.14
ENSMUST00000142680.2
Ap2b1
adaptor-related protein complex 2, beta 1 subunit
chr5_-_86475595 0.06 ENSMUST00000122377.2
Tmprss11d
transmembrane protease, serine 11d
chr2_+_51928017 0.06 ENSMUST00000065927.6
Tnfaip6
tumor necrosis factor alpha induced protein 6
chr11_+_58549642 0.05 ENSMUST00000214392.2
Olfr322
olfactory receptor 322
chr7_-_99629637 0.05 ENSMUST00000080817.6
Rnf169
ring finger protein 169
chr11_-_75330415 0.05 ENSMUST00000128330.8
Serpinf2
serine (or cysteine) peptidase inhibitor, clade F, member 2
chrY_-_70026134 0.05 ENSMUST00000188554.7
ENSMUST00000191151.2
Gm28079
predicted gene 28079
chr14_-_70867588 0.05 ENSMUST00000228009.2
Dmtn
dematin actin binding protein
chr2_+_131792774 0.04 ENSMUST00000110170.8
ENSMUST00000110172.9
ENSMUST00000110171.9
Prnd
prion like protein doppel
chr5_-_23889591 0.03 ENSMUST00000198549.2
Srpk2
serine/arginine-rich protein specific kinase 2
chrX_-_49517375 0.03 ENSMUST00000215270.2
Olfr1324
olfactory receptor 1324
chr12_-_101924407 0.02 ENSMUST00000159883.2
ENSMUST00000160251.8
ENSMUST00000161011.8
ENSMUST00000021606.12
Atxn3
ataxin 3
chr18_+_68470616 0.02 ENSMUST00000172148.4
ENSMUST00000239469.2
Mc5r
melanocortin 5 receptor
chr10_+_57521930 0.02 ENSMUST00000177325.8
Pkib
protein kinase inhibitor beta, cAMP dependent, testis specific
chr10_+_42736771 0.02 ENSMUST00000105494.8
Scml4
Scm polycomb group protein like 4
chr10_+_57521958 0.02 ENSMUST00000177473.8
Pkib
protein kinase inhibitor beta, cAMP dependent, testis specific
chr18_+_89224219 0.01 ENSMUST00000236835.2
Cd226
CD226 antigen
chr16_+_43056218 0.01 ENSMUST00000146708.8
Zbtb20
zinc finger and BTB domain containing 20
chr6_+_38895902 0.01 ENSMUST00000003017.13
Tbxas1
thromboxane A synthase 1, platelet
chr15_-_6904450 0.01 ENSMUST00000022746.13
ENSMUST00000176826.2
Osmr
oncostatin M receptor
chr1_+_88334678 0.01 ENSMUST00000027518.12
Spp2
secreted phosphoprotein 2
chr5_+_148202117 0.01 ENSMUST00000110514.8
Mtus2
microtubule associated tumor suppressor candidate 2
chr5_+_148202075 0.00 ENSMUST00000071878.12
Mtus2
microtubule associated tumor suppressor candidate 2
chr7_-_142223662 0.00 ENSMUST00000228850.2
Gm49394
predicted gene, 49394
chr6_-_21851827 0.00 ENSMUST00000202353.2
ENSMUST00000134635.2
ENSMUST00000123116.8
ENSMUST00000120965.8
ENSMUST00000143531.2
Tspan12
tetraspanin 12
chr1_+_6805048 0.00 ENSMUST00000139838.8
St18
suppression of tumorigenicity 18

Network of associatons between targets according to the STRING database.

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:1900104 hyaluranon cable assembly(GO:0036118) nephrogenic mesenchyme development(GO:0072076) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.1 0.3 GO:0006548 histidine catabolic process(GO:0006548)
0.1 0.4 GO:0035063 nuclear speck organization(GO:0035063)
0.1 0.4 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.0 0.3 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.0 0.1 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.0 0.1 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.0 0.1 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.0 0.2 GO:0036438 maintenance of lens transparency(GO:0036438)
0.0 0.2 GO:0030035 microspike assembly(GO:0030035)
0.0 0.1 GO:1904116 response to vasopressin(GO:1904116) cellular response to vasopressin(GO:1904117)
0.0 0.1 GO:0061534 gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
0.0 0.1 GO:0002034 regulation of blood vessel size by renin-angiotensin(GO:0002034) renal control of peripheral vascular resistance involved in regulation of systemic arterial blood pressure(GO:0003072)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0097441 basilar dendrite(GO:0097441)
0.0 0.1 GO:0005577 fibrinogen complex(GO:0005577)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 GO:0016841 ammonia-lyase activity(GO:0016841)
0.0 0.2 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.5 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.3 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.0 0.2 GO:0005313 L-glutamate transmembrane transporter activity(GO:0005313)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 PID ALK2 PATHWAY ALK2 signaling events