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GFI1 WT vs 36n/n vs KD

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Results for Hcfc1_Six5_Smarcc2_Zfp143

Z-value: 5.66

Motif logo

Transcription factors associated with Hcfc1_Six5_Smarcc2_Zfp143

Gene Symbol Gene ID Gene Info
ENSMUSG00000031386.15 host cell factor C1
ENSMUSG00000040841.6 sine oculis-related homeobox 5
ENSMUSG00000025369.16 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2
ENSMUSG00000061079.15 zinc finger protein 143

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Hcfc1mm39_v1_chrX_-_73009933_73009982-0.885.0e-02Click!
Smarcc2mm39_v1_chr10_+_128295159_128295197-0.857.1e-02Click!
Six5mm39_v1_chr7_+_18828519_18828558-0.761.3e-01Click!
Zfp143mm39_v1_chr7_+_109660887_1096609500.118.6e-01Click!

Activity profile of Hcfc1_Six5_Smarcc2_Zfp143 motif

Sorted Z-values of Hcfc1_Six5_Smarcc2_Zfp143 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr4_+_134123631 3.47 ENSMUST00000105869.9
platelet-activating factor acetylhydrolase 2
chr18_-_42395207 3.23 ENSMUST00000097590.5
leucyl-tRNA synthetase
chr5_+_31350607 3.21 ENSMUST00000201535.4
sorting nexin 17
chr3_-_89009153 3.15 ENSMUST00000199668.3
ENSMUST00000196709.5
farnesyl diphosphate synthetase
chr7_+_115692530 3.13 ENSMUST00000032899.12
ENSMUST00000106608.8
ENSMUST00000106607.2
RIKEN cDNA 1110004F10 gene
chr11_-_117764258 3.00 ENSMUST00000033230.8
threonine aldolase 1
chr16_-_75563645 2.99 ENSMUST00000114244.2
ENSMUST00000046283.16
heat shock protein 70 family, member 13
chr1_-_60137294 2.90 ENSMUST00000141417.3
ENSMUST00000122038.8
WD repeat domain 12
chr7_+_127344942 2.77 ENSMUST00000189562.7
ENSMUST00000186116.7
F-box and leucine-rich repeat protein 19
chr11_+_95557783 2.62 ENSMUST00000125172.8
ENSMUST00000036374.6
prohibitin
chr1_-_16727133 2.62 ENSMUST00000185771.7
elongin C
chr17_-_35984409 2.55 ENSMUST00000162266.8
ENSMUST00000160734.8
ENSMUST00000159852.2
ENSMUST00000160039.8
general transcription factor II H, polypeptide 4
chr3_-_89009214 2.54 ENSMUST00000081848.13
farnesyl diphosphate synthetase
chr7_-_24672055 2.50 ENSMUST00000205871.2
Rab acceptor 1 (prenylated)
chrX_-_7471613 2.48 ENSMUST00000033483.5
coiled-coil domain containing 22
chr19_-_10181243 2.46 ENSMUST00000142241.2
ENSMUST00000116542.9
ENSMUST00000025651.6
ENSMUST00000156291.2
flap structure specific endonuclease 1
chr6_+_95094721 2.39 ENSMUST00000032107.10
ENSMUST00000119582.3
kelch repeat and BTB (POZ) domain containing 8
chr15_+_102426838 2.37 ENSMUST00000229805.2
ENSMUST00000150393.9
ENSMUST00000023813.9
TARBP2, RISC loading complex RNA binding subunit
chr10_-_80736579 2.34 ENSMUST00000218481.2
ENSMUST00000219896.2
ENSMUST00000020440.7
translocase of inner mitochondrial membrane 13
chr15_-_81614063 2.34 ENSMUST00000171115.3
ENSMUST00000170134.9
ENSMUST00000052374.13
RAN GTPase activating protein 1
chr11_-_29497819 2.32 ENSMUST00000102844.4
ribosomal protein S27A
chr7_+_16186704 2.28 ENSMUST00000019302.10
transmembrane protein 160
chr15_+_102426742 2.26 ENSMUST00000100168.10
TARBP2, RISC loading complex RNA binding subunit
chr5_-_24628483 2.24 ENSMUST00000198990.2
cyclin-dependent kinase 5
chr7_+_131162137 2.22 ENSMUST00000207231.2
BUB3 mitotic checkpoint protein
chr15_+_44291470 2.19 ENSMUST00000226827.2
ENSMUST00000060652.5
ENY2 transcription and export complex 2 subunit
chr1_-_60137263 2.19 ENSMUST00000143342.8
WD repeat domain 12
chr15_+_102427149 2.18 ENSMUST00000146756.8
ENSMUST00000142194.3
TARBP2, RISC loading complex RNA binding subunit
chr14_+_20344765 2.18 ENSMUST00000223663.2
ENSMUST00000022343.6
ENSMUST00000224066.2
ENSMUST00000223941.2
ENSMUST00000224311.2
nudix (nucleoside diphosphate linked moiety X)-type motif 13
chr6_+_72575458 2.18 ENSMUST00000070597.13
ENSMUST00000176364.8
ENSMUST00000176168.3
retinol saturase (all trans retinol 13,14 reductase)
chr2_-_84557694 2.16 ENSMUST00000028475.9
CLP1, cleavage and polyadenylation factor I subunit
chr2_-_154916367 2.16 ENSMUST00000137242.2
ENSMUST00000054607.16
S-adenosylhomocysteine hydrolase
chr11_+_69886652 2.13 ENSMUST00000101526.9
PHD finger protein 23
chr7_-_99508117 2.13 ENSMUST00000209032.2
ENSMUST00000036274.8
signal peptidase complex subunit 2 homolog (S. cerevisiae)
chr2_-_25911544 2.10 ENSMUST00000136750.3
ubiquitin associated domain containing 1
chr7_-_12788441 2.06 ENSMUST00000182087.2
myeloid zinc finger 1
chr8_+_106786190 2.05 ENSMUST00000109308.3
nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 3
chr1_-_86510222 2.05 ENSMUST00000027444.15
ENSMUST00000146220.2
phosphodiesterase 6D, cGMP-specific, rod, delta
chr12_-_87194658 2.04 ENSMUST00000037788.6
protein-O-mannosyltransferase 2
chr8_+_86219191 2.00 ENSMUST00000034136.12
glutamic pyruvate transaminase (alanine aminotransferase) 2
chr17_-_23892798 1.97 ENSMUST00000047436.11
ENSMUST00000115490.9
ENSMUST00000095579.11
THO complex 6
chr3_+_97066065 1.93 ENSMUST00000090759.5
acid phosphatase 6, lysophosphatidic
chr7_-_99508066 1.93 ENSMUST00000208477.2
ENSMUST00000208465.2
signal peptidase complex subunit 2 homolog (S. cerevisiae)
chr1_-_16727242 1.90 ENSMUST00000186948.7
ENSMUST00000187910.7
ENSMUST00000115352.10
elongin C
chr4_+_156194427 1.89 ENSMUST00000072554.13
ENSMUST00000169550.8
ENSMUST00000105576.2
RIKEN cDNA 9430015G10 gene
chr5_-_31350352 1.88 ENSMUST00000202758.4
ENSMUST00000114603.8
eukaryotic translation initiation factor 2B, subunit 4 delta
chr7_-_12788592 1.87 ENSMUST00000182515.8
ENSMUST00000069289.15
myeloid zinc finger 1
chr9_-_78015866 1.86 ENSMUST00000162625.2
ENSMUST00000159099.8
ENSMUST00000085311.13
f-box protein 9
chr4_+_116565819 1.85 ENSMUST00000106463.8
coiled-coil domain containing 163
chr6_-_124806359 1.85 ENSMUST00000142058.8
ENSMUST00000122110.8
ubiquitin specific peptidase 5 (isopeptidase T)
chr16_-_35311243 1.82 ENSMUST00000023550.9
protein disulfide isomerase associated 5
chr11_-_31621863 1.80 ENSMUST00000058060.14
biorientation of chromosomes in cell division 1
chr9_+_48966868 1.78 ENSMUST00000034803.10
zw10 kinetochore protein
chr15_-_44291699 1.78 ENSMUST00000038719.8
NudC domain containing 1
chr7_-_24672083 1.78 ENSMUST00000076961.9
Rab acceptor 1 (prenylated)
chr2_+_118428690 1.76 ENSMUST00000038341.8
BUB1B, mitotic checkpoint serine/threonine kinase
chr7_-_27373939 1.75 ENSMUST00000138243.2
mitogen-activated protein kinase kinase kinase 10
chr7_+_92210348 1.74 ENSMUST00000032842.13
ENSMUST00000085017.5
coiled-coil domain containing 90B
chr18_-_42395131 1.72 ENSMUST00000236102.2
leucyl-tRNA synthetase
chr5_+_33815466 1.71 ENSMUST00000074849.13
ENSMUST00000079534.11
ENSMUST00000201633.2
transforming, acidic coiled-coil containing protein 3
chr12_+_55883101 1.70 ENSMUST00000059250.8
breast cancer metastasis-suppressor 1-like
chr10_-_127147609 1.65 ENSMUST00000037290.12
ENSMUST00000171564.8
methionine-tRNA synthetase 1
chr8_-_57940834 1.64 ENSMUST00000034022.4
sin3 associated polypeptide
chrX_-_139857424 1.64 ENSMUST00000033805.15
ENSMUST00000112978.2
proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
chr7_+_43321426 1.63 ENSMUST00000038332.9
cytosolic thiouridylase subunit 1
chr19_-_47039261 1.63 ENSMUST00000026032.7
polycomb group ring finger 6
chr7_+_44117511 1.63 ENSMUST00000121922.3
ENSMUST00000208117.2
Josephin domain containing 2
chr13_+_32985990 1.63 ENSMUST00000021832.7
Werner helicase interacting protein 1
chr16_+_20354225 1.63 ENSMUST00000090023.13
ENSMUST00000007216.9
ENSMUST00000232001.2
adaptor-related protein complex 2, mu 1 subunit
chr11_-_69906171 1.63 ENSMUST00000018718.8
ENSMUST00000102574.10
acyl-Coenzyme A dehydrogenase, very long chain
chr7_+_44117444 1.63 ENSMUST00000206887.2
ENSMUST00000117324.8
ENSMUST00000120852.8
ENSMUST00000134398.3
ENSMUST00000118628.8
Josephin domain containing 2
chr7_-_27374017 1.61 ENSMUST00000036453.14
ENSMUST00000108341.2
mitogen-activated protein kinase kinase kinase 10
chr6_-_128414616 1.61 ENSMUST00000151796.3
FK506 binding protein 4
chr18_-_24153363 1.61 ENSMUST00000153337.2
ENSMUST00000148525.2
zinc finger protein 24
chr6_+_122285615 1.60 ENSMUST00000007602.15
ENSMUST00000112610.2
mannose-6-phosphate receptor, cation dependent
chr5_-_149559792 1.59 ENSMUST00000202361.4
ENSMUST00000202089.4
ENSMUST00000200825.2
ENSMUST00000201559.4
heat shock 105kDa/110kDa protein 1
chr4_+_155048571 1.59 ENSMUST00000030931.11
ENSMUST00000070953.11
pantothenate kinase 4
chr15_+_76788270 1.58 ENSMUST00000004072.10
ENSMUST00000229183.2
ribosomal protein L8
chr9_+_107464841 1.57 ENSMUST00000010192.11
interferon-related developmental regulator 2
chr3_+_87826834 1.57 ENSMUST00000137775.2
mitochondrial ribosomal protein L24
chr10_-_80754016 1.56 ENSMUST00000057623.14
ENSMUST00000179022.8
lamin B2
chr5_+_31350566 1.55 ENSMUST00000031029.15
ENSMUST00000201679.4
sorting nexin 17
chr6_-_34153955 1.54 ENSMUST00000019143.9
solute carrier family 35, member B4
chr10_-_128384971 1.54 ENSMUST00000176906.2
ribosomal protein L41
chr6_-_87649173 1.52 ENSMUST00000032130.8
aprataxin and PNKP like factor
chr10_+_76869046 1.52 ENSMUST00000105410.10
solute carrier family 19 (folate transporter), member 1
chr17_+_46471950 1.50 ENSMUST00000024748.14
ENSMUST00000172170.8
GTP binding protein 2
chr9_+_66033893 1.50 ENSMUST00000034945.6
cytosolic iron-sulfur assembly component 2A
chr10_-_119075910 1.50 ENSMUST00000020315.13
cullin associated and neddylation disassociated 1
chr15_-_76396151 1.49 ENSMUST00000023214.11
diacylglycerol O-acyltransferase 1
chr6_-_124806430 1.47 ENSMUST00000047510.10
ubiquitin specific peptidase 5 (isopeptidase T)
chr16_-_84632439 1.47 ENSMUST00000138279.2
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F
chr8_+_80366247 1.47 ENSMUST00000173078.8
ENSMUST00000173286.8
OTU domain containing 4
chr6_+_117840031 1.45 ENSMUST00000172088.8
ENSMUST00000079405.15
zinc finger protein 239
chr3_+_95801325 1.45 ENSMUST00000197081.2
ENSMUST00000056710.10
aph1 homolog A, gamma secretase subunit
chr16_-_91728162 1.44 ENSMUST00000139277.8
ENSMUST00000154661.8
ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit
chr8_-_107775204 1.44 ENSMUST00000055316.10
peptide deformylase (mitochondrial)
chr4_-_116664729 1.42 ENSMUST00000106455.8
ENSMUST00000030451.10
target of EGR1, member 1 (nuclear)
chr6_-_83031358 1.41 ENSMUST00000113962.8
ENSMUST00000089645.13
ENSMUST00000113963.8
HtrA serine peptidase 2
chr11_-_70860778 1.40 ENSMUST00000108530.2
ENSMUST00000035283.11
ENSMUST00000108531.8
nucleoporin 88
chr18_-_24153805 1.39 ENSMUST00000066497.12
zinc finger protein 24
chr2_-_127089540 1.39 ENSMUST00000174030.8
ENSMUST00000174863.8
cytosolic iron-sulfur protein assembly 1
chr9_+_19533374 1.39 ENSMUST00000213725.2
ENSMUST00000208694.2
zinc finger protein 317
chr7_+_16472335 1.38 ENSMUST00000086112.8
ENSMUST00000205607.2
adaptor-related protein complex 2, sigma 1 subunit
chr4_+_116565898 1.38 ENSMUST00000135499.8
coiled-coil domain containing 163
chr16_+_4501934 1.38 ENSMUST00000060067.12
ENSMUST00000115854.4
ENSMUST00000229529.2
DnaJ heat shock protein family (Hsp40) member A3
chr9_-_26910833 1.34 ENSMUST00000060513.8
ENSMUST00000120367.8
acyl-Coenzyme A dehydrogenase family, member 8
chr11_-_5492175 1.33 ENSMUST00000020776.5
coiled-coil domain containing 117
chr15_-_75801630 1.33 ENSMUST00000229289.2
ENSMUST00000229641.2
GDP-L-fucose synthase
chr11_+_117740077 1.33 ENSMUST00000081387.11
baculoviral IAP repeat-containing 5
chr12_-_83643883 1.33 ENSMUST00000221919.2
zinc finger, FYVE domain containing 1
chr13_-_54737857 1.32 ENSMUST00000148222.2
ENSMUST00000026987.12
NOP16 nucleolar protein
chr9_-_103079312 1.32 ENSMUST00000035157.10
signal recognition particle receptor, B subunit
chr13_+_55740948 1.32 ENSMUST00000109905.5
transmembrane p24 trafficking protein 9
chr17_+_24851647 1.31 ENSMUST00000047611.4
nth (endonuclease III)-like 1 (E.coli)
chr11_+_69886603 1.30 ENSMUST00000018716.10
PHD finger protein 23
chr10_+_93289264 1.29 ENSMUST00000016033.9
leukotriene A4 hydrolase
chr6_+_142702403 1.29 ENSMUST00000032419.9
cytidine monophospho-N-acetylneuraminic acid synthetase
chr7_+_44117475 1.29 ENSMUST00000118493.8
Josephin domain containing 2
chr12_-_87312982 1.27 ENSMUST00000179379.9
VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog
chr7_+_44117404 1.25 ENSMUST00000035844.11
Josephin domain containing 2
chr7_+_12631727 1.25 ENSMUST00000055528.11
ENSMUST00000117189.2
ENSMUST00000120809.2
ENSMUST00000119989.3
zinc finger and SCAN domain containing 22
chr17_-_56916771 1.25 ENSMUST00000052832.6
mitochondrial contact site and cristae organizing system subunit 13
chr2_+_32647246 1.24 ENSMUST00000009707.14
ENSMUST00000177382.2
ENSMUST00000140999.2
torsin family 2, member A
chr4_+_149188585 1.24 ENSMUST00000103216.10
ENSMUST00000030816.4
DNA fragmentation factor, alpha subunit
chr1_-_44157916 1.24 ENSMUST00000027213.14
ENSMUST00000065767.9
protein O-glucosyltransferase 2
chr8_+_70625032 1.24 ENSMUST00000002413.15
ENSMUST00000182980.8
ENSMUST00000182365.8
transmembrane protein 161A
chr15_+_76235488 1.24 ENSMUST00000161527.8
ENSMUST00000160853.8
MAF1 homolog, negative regulator of RNA polymerase III
chr17_-_30831576 1.23 ENSMUST00000235171.2
ENSMUST00000236335.2
ENSMUST00000167624.2
glyoxalase 1
chr19_-_4062738 1.23 ENSMUST00000136921.2
ENSMUST00000042497.14
NADH:ubiquinone oxidoreductase core subunit V1
chr4_-_49521036 1.23 ENSMUST00000057829.4
mitochondrial ribosomal protein L50
chr12_+_10440755 1.22 ENSMUST00000020947.7
retinol dehydrogenase 14 (all-trans and 9-cis)
chr15_+_76235503 1.21 ENSMUST00000023212.15
ENSMUST00000160172.8
MAF1 homolog, negative regulator of RNA polymerase III
chr9_+_109704609 1.21 ENSMUST00000094324.8
cell division cycle 25A
chr6_+_91450677 1.21 ENSMUST00000032183.6
transmembrane protein 43
chr11_+_32592707 1.20 ENSMUST00000109366.8
ENSMUST00000093205.13
ENSMUST00000076383.8
F-box and WD-40 domain protein 11
chr10_-_121462219 1.18 ENSMUST00000039810.8
ENSMUST00000218004.2
exportin, tRNA (nuclear export receptor for tRNAs)
chr6_-_89572629 1.18 ENSMUST00000113550.6
ENSMUST00000032172.14
coiled-coil-helix-coiled-coil-helix domain containing 6
chr15_-_57755753 1.18 ENSMUST00000022993.7
Der1-like domain family, member 1
chr4_+_107035615 1.18 ENSMUST00000128123.3
ENSMUST00000106753.3
transmembrane protein 59
chr1_-_93563406 1.18 ENSMUST00000027498.14
serine/threonine kinase 25 (yeast)
chr10_+_79978152 1.18 ENSMUST00000105366.2
ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit
chr19_-_4062656 1.17 ENSMUST00000134479.8
ENSMUST00000128787.8
ENSMUST00000237862.2
ENSMUST00000236203.2
ENSMUST00000133474.8
NADH:ubiquinone oxidoreductase core subunit V1
chr16_-_37360097 1.17 ENSMUST00000023525.9
general transcription factor II E, polypeptide 1 (alpha subunit)
chr7_-_29869126 1.16 ENSMUST00000062181.9
zinc finger protein 146
chr1_-_16727067 1.15 ENSMUST00000188641.7
elongin C
chr9_-_35087348 1.14 ENSMUST00000119847.2
ENSMUST00000034539.12
decapping enzyme, scavenger
chr7_+_122977205 1.14 ENSMUST00000033025.7
ENSMUST00000206574.2
leucine carboxyl methyltransferase 1
chr2_+_29692638 1.13 ENSMUST00000080065.3
solute carrier family 27 (fatty acid transporter), member 4
chr7_-_128063053 1.13 ENSMUST00000141126.8
ENSMUST00000033135.9
Tia1 cytotoxic granule-associated RNA binding protein-like 1
chr6_-_4086914 1.13 ENSMUST00000049166.5
Bet1 golgi vesicular membrane trafficking protein
chr5_-_115622356 1.13 ENSMUST00000112067.8
sirtuin 4
chr3_-_87792865 1.13 ENSMUST00000005015.10
papillary renal cell carcinoma (translocation-associated)
chr9_-_48391838 1.12 ENSMUST00000216470.2
ENSMUST00000217037.2
ENSMUST00000034524.5
ENSMUST00000213895.2
RNA exonuclease 2
chr2_-_84557580 1.12 ENSMUST00000165219.8
CLP1, cleavage and polyadenylation factor I subunit
chr5_-_5564730 1.12 ENSMUST00000115445.8
ENSMUST00000179804.8
ENSMUST00000125110.2
ENSMUST00000115446.8
claudin 12
chr15_+_88960327 1.12 ENSMUST00000165690.2
TraB domain containing
chr7_+_131162338 1.12 ENSMUST00000208571.2
BUB3 mitotic checkpoint protein
chr7_-_45480200 1.11 ENSMUST00000107723.9
ENSMUST00000131384.3
glutamate-rich WD repeat containing 1
chr8_+_71995554 1.10 ENSMUST00000034272.9
multivesicular body subunit 12A
chr15_-_75801575 1.10 ENSMUST00000229951.2
ENSMUST00000023231.7
ENSMUST00000230736.2
GDP-L-fucose synthase
chr4_+_116565706 1.09 ENSMUST00000030452.13
ENSMUST00000106462.9
coiled-coil domain containing 163
chr3_+_103821413 1.09 ENSMUST00000051139.13
ENSMUST00000068879.11
rosbin, round spermatid basic protein 1
chr6_+_85429023 1.09 ENSMUST00000204592.3
chaperonin containing Tcp1, subunit 7 (eta)
chr2_+_154498917 1.09 ENSMUST00000044277.10
charged multivesicular body protein 4B
chr2_+_128942900 1.09 ENSMUST00000103205.11
polymerase (RNA) I polypeptide B
chr3_-_19217174 1.06 ENSMUST00000029125.10
armadillo repeat containing 1
chr19_+_36061096 1.06 ENSMUST00000025714.9
ribonuclease P/MRP 30 subunit
chr11_-_59937302 1.06 ENSMUST00000000310.14
ENSMUST00000102693.9
ENSMUST00000148512.2
phosphatidylethanolamine N-methyltransferase
chr13_-_54616618 1.05 ENSMUST00000026990.6
THO complex 3
chr1_-_74323795 1.05 ENSMUST00000178235.8
ENSMUST00000006462.14
angio-associated migratory protein
chr11_-_60769589 1.05 ENSMUST00000155031.2
transmembrane protein 11
chr2_+_128942919 1.04 ENSMUST00000028874.8
polymerase (RNA) I polypeptide B
chr7_+_131161951 1.03 ENSMUST00000084502.7
BUB3 mitotic checkpoint protein
chr11_-_21521934 1.03 ENSMUST00000239073.2
malate dehydrogenase 1, NAD (soluble)
chr9_-_78016302 1.03 ENSMUST00000001402.14
f-box protein 9
chr16_-_91525485 1.02 ENSMUST00000231499.2
ENSMUST00000141664.9
ENSMUST00000123751.2
ENSMUST00000122254.8
ENSMUST00000114023.3
crystallin, zeta (quinone reductase)-like 1
chr3_+_100829798 1.02 ENSMUST00000106980.9
tripartite motif-containing 45
chr16_-_91525655 1.01 ENSMUST00000117644.8
crystallin, zeta (quinone reductase)-like 1
chr11_-_21522193 1.01 ENSMUST00000102874.11
ENSMUST00000238916.2
malate dehydrogenase 1, NAD (soluble)
chr9_+_19533591 1.00 ENSMUST00000215372.2
zinc finger protein 317
chr12_+_87194476 1.00 ENSMUST00000063117.10
ENSMUST00000220574.2
glutathione transferase zeta 1 (maleylacetoacetate isomerase)
chr12_+_105976463 1.00 ENSMUST00000072040.7
vaccinia related kinase 1
chr7_-_127494750 1.00 ENSMUST00000033074.8
vitamin K epoxide reductase complex, subunit 1
chr11_+_76297969 0.99 ENSMUST00000021203.7
ENSMUST00000152183.2
translocase of inner mitochondrial membrane 22
chr16_-_43709968 0.99 ENSMUST00000023387.14
queuine tRNA-ribosyltransferase accessory subunit 2
chr6_+_117818135 0.99 ENSMUST00000112859.8
ENSMUST00000137224.8
ENSMUST00000164472.8
ENSMUST00000112861.8
ENSMUST00000223041.2
zinc finger protein 637
chr7_+_3632982 0.99 ENSMUST00000179769.8
ENSMUST00000008517.13
pre-mRNA processing factor 31
chr11_-_31621727 0.97 ENSMUST00000109415.2
biorientation of chromosomes in cell division 1
chr7_+_29794575 0.97 ENSMUST00000130526.2
ENSMUST00000108200.2
zinc finger protein 260
chr14_+_55909692 0.96 ENSMUST00000002397.7
guanosine monophosphate reductase 2
chr3_+_85481416 0.96 ENSMUST00000107672.8
ENSMUST00000127348.8
ENSMUST00000107674.2
glutamyl-tRNA(Gln) amidotransferase, subunit B
chrX_-_17438520 0.95 ENSMUST00000026016.13
FUN14 domain containing 1
chr2_+_118943274 0.95 ENSMUST00000140939.8
ENSMUST00000028795.10
RAD51 recombinase
chr12_-_87312994 0.94 ENSMUST00000072744.15
VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog
chrX_+_139857640 0.94 ENSMUST00000112971.2
autophagy related 4A, cysteine peptidase
chr16_+_35803794 0.94 ENSMUST00000173555.8
karyopherin (importin) alpha 1
chr2_+_101716577 0.94 ENSMUST00000028584.8
COMM domain containing 9
chr13_+_104315301 0.94 ENSMUST00000022225.12
ENSMUST00000069187.12
tripartite motif-containing 23
chr16_-_91525863 0.93 ENSMUST00000073466.13
crystallin, zeta (quinone reductase)-like 1

Network of associatons between targets according to the STRING database.

First level regulatory network of Hcfc1_Six5_Smarcc2_Zfp143

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 10.1 GO:0030423 targeting of mRNA for destruction involved in RNA interference(GO:0030423)
1.6 4.9 GO:0006429 leucyl-tRNA aminoacylation(GO:0006429)
1.4 5.7 GO:0045338 farnesyl diphosphate metabolic process(GO:0045338)
0.7 3.3 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.6 3.0 GO:0006566 threonine metabolic process(GO:0006566)
0.6 1.8 GO:0046038 GMP catabolic process(GO:0046038)
0.5 1.6 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.5 2.2 GO:0002439 chronic inflammatory response to antigenic stimulus(GO:0002439)
0.5 2.1 GO:0017126 nucleologenesis(GO:0017126)
0.5 1.6 GO:1900063 mitochondrial membrane fission(GO:0090149) regulation of peroxisome organization(GO:1900063)
0.5 3.1 GO:0098838 reduced folate transmembrane transport(GO:0098838)
0.5 2.6 GO:0045917 positive regulation of complement activation(GO:0045917) positive regulation of protein activation cascade(GO:2000259)
0.5 5.2 GO:0036481 intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:0036481)
0.5 1.5 GO:0090481 GDP-fucose transport(GO:0015783) purine nucleotide-sugar transport(GO:0036079) pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.5 3.1 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.5 2.0 GO:0042851 L-alanine metabolic process(GO:0042851)
0.5 1.5 GO:0019747 regulation of isoprenoid metabolic process(GO:0019747) regulation of vitamin A metabolic process(GO:1901738)
0.5 5.4 GO:0046826 negative regulation of protein export from nucleus(GO:0046826)
0.5 1.4 GO:0043686 co-translational protein modification(GO:0043686)
0.5 6.2 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.5 1.4 GO:1904924 negative regulation of mitophagy in response to mitochondrial depolarization(GO:1904924)
0.4 1.3 GO:0006285 base-excision repair, AP site formation(GO:0006285) nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296)
0.4 1.6 GO:0072355 histone H3-T3 phosphorylation(GO:0072355)
0.4 5.1 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.4 1.1 GO:0036245 cellular response to menadione(GO:0036245)
0.4 1.1 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.4 1.4 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.4 1.8 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.3 1.3 GO:0035964 COPI-coated vesicle budding(GO:0035964)
0.3 1.3 GO:0071431 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.3 1.3 GO:0046381 CMP-N-acetylneuraminate metabolic process(GO:0046381)
0.3 1.0 GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.3 0.9 GO:1990426 homologous recombination-dependent replication fork processing(GO:1990426)
0.3 0.9 GO:0052564 interleukin-15 production(GO:0032618) response to immune response of other organism involved in symbiotic interaction(GO:0052564) response to host immune response(GO:0052572)
0.3 0.9 GO:1902774 late endosome to lysosome transport(GO:1902774)
0.3 3.0 GO:0042760 very long-chain fatty acid catabolic process(GO:0042760)
0.3 2.0 GO:1904098 regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
0.3 2.9 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.3 0.9 GO:0036367 adaptation of rhodopsin mediated signaling(GO:0016062) light adaption(GO:0036367)
0.3 1.7 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.3 0.8 GO:0048478 replication fork protection(GO:0048478)
0.3 0.8 GO:1902220 positive regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902220)
0.3 0.8 GO:0006624 vacuolar protein processing(GO:0006624)
0.3 1.6 GO:0034227 tRNA thio-modification(GO:0034227)
0.3 2.4 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.3 0.5 GO:0036090 cleavage furrow ingression(GO:0036090)
0.3 1.0 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.3 0.3 GO:1990009 retinal cell apoptotic process(GO:1990009)
0.2 1.0 GO:0017187 peptidyl-glutamic acid carboxylation(GO:0017187)
0.2 4.7 GO:0006465 signal peptide processing(GO:0006465)
0.2 3.5 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.2 2.4 GO:0032074 negative regulation of nuclease activity(GO:0032074)
0.2 1.7 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.2 1.6 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.2 1.6 GO:0031536 positive regulation of exit from mitosis(GO:0031536)
0.2 1.4 GO:0060336 negative regulation of response to interferon-gamma(GO:0060331) negative regulation of interferon-gamma-mediated signaling pathway(GO:0060336)
0.2 1.1 GO:0006481 C-terminal protein methylation(GO:0006481)
0.2 2.0 GO:0006108 malate metabolic process(GO:0006108)
0.2 0.9 GO:0022007 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.2 1.1 GO:0009052 pentose-phosphate shunt, non-oxidative branch(GO:0009052)
0.2 2.2 GO:0017185 peptidyl-lysine hydroxylation(GO:0017185)
0.2 2.1 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.2 0.6 GO:1990164 histone H2A phosphorylation(GO:1990164)
0.2 5.9 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.2 1.1 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
0.2 0.6 GO:0030573 bile acid catabolic process(GO:0030573)
0.2 1.6 GO:0006572 tyrosine catabolic process(GO:0006572)
0.2 1.0 GO:2001270 regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270)
0.2 1.0 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.2 4.2 GO:0031163 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.2 1.7 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.2 0.7 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.2 0.7 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.2 1.1 GO:0099527 postsynapse to nucleus signaling pathway(GO:0099527)
0.2 1.3 GO:1903772 regulation of viral budding via host ESCRT complex(GO:1903772)
0.2 3.5 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.2 5.6 GO:0032968 positive regulation of transcription elongation from RNA polymerase II promoter(GO:0032968)
0.2 0.5 GO:0090285 negative regulation of protein glycosylation in Golgi(GO:0090285)
0.2 0.5 GO:0046168 glycerol-3-phosphate catabolic process(GO:0046168)
0.2 1.0 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.2 4.0 GO:0042994 cytoplasmic sequestering of transcription factor(GO:0042994)
0.2 0.7 GO:0071287 peptidyl-aspartic acid modification(GO:0018197) cellular response to manganese ion(GO:0071287)
0.2 2.4 GO:1904851 positive regulation of establishment of protein localization to telomere(GO:1904851)
0.2 0.6 GO:0046077 dUDP biosynthetic process(GO:0006227) pyrimidine nucleoside diphosphate metabolic process(GO:0009138) pyrimidine nucleoside diphosphate biosynthetic process(GO:0009139) pyrimidine deoxyribonucleoside diphosphate metabolic process(GO:0009196) pyrimidine deoxyribonucleoside diphosphate biosynthetic process(GO:0009197) dUDP metabolic process(GO:0046077)
0.2 2.7 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.2 4.1 GO:0042572 retinol metabolic process(GO:0042572)
0.2 0.3 GO:1904871 protein localization to nuclear body(GO:1903405) protein localization to Cajal body(GO:1904867) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871)
0.2 1.4 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.2 0.6 GO:1900060 negative regulation of ceramide biosynthetic process(GO:1900060)
0.2 0.5 GO:0045041 protein import into mitochondrial intermembrane space(GO:0045041)
0.2 0.5 GO:0040030 regulation of molecular function, epigenetic(GO:0040030)
0.2 1.2 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
0.2 0.8 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
0.2 1.1 GO:0050747 positive regulation of lipoprotein metabolic process(GO:0050747)
0.2 0.8 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.1 0.4 GO:0019264 glycine biosynthetic process from serine(GO:0019264)
0.1 2.1 GO:0034501 protein localization to kinetochore(GO:0034501)
0.1 1.0 GO:0045716 positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716)
0.1 3.9 GO:0015986 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.1 0.6 GO:1904046 negative regulation of vascular endothelial growth factor production(GO:1904046)
0.1 1.8 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.1 0.8 GO:0032053 ciliary basal body organization(GO:0032053)
0.1 0.3 GO:0000720 pyrimidine dimer repair by nucleotide-excision repair(GO:0000720)
0.1 0.3 GO:0071034 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.1 4.8 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.1 0.3 GO:0033567 DNA replication, Okazaki fragment processing(GO:0033567)
0.1 1.6 GO:0043248 proteasome assembly(GO:0043248)
0.1 0.5 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.1 1.6 GO:0033299 secretion of lysosomal enzymes(GO:0033299)
0.1 1.4 GO:0014029 neural crest formation(GO:0014029)
0.1 0.4 GO:0070839 divalent metal ion export(GO:0070839)
0.1 0.6 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.1 0.2 GO:0050689 negative regulation of defense response to virus by host(GO:0050689)
0.1 1.4 GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.1 2.6 GO:0006613 cotranslational protein targeting to membrane(GO:0006613)
0.1 1.4 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.1 1.2 GO:0071763 nuclear membrane organization(GO:0071763)
0.1 0.3 GO:0006272 leading strand elongation(GO:0006272) mitotic telomere maintenance via semi-conservative replication(GO:1902990)
0.1 2.2 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.1 0.5 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.1 0.8 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.1 0.7 GO:0051105 regulation of DNA ligation(GO:0051105) positive regulation of DNA ligation(GO:0051106)
0.1 0.5 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.1 2.0 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.1 0.4 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
0.1 0.6 GO:1904749 regulation of protein localization to nucleolus(GO:1904749)
0.1 1.1 GO:0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.1 0.3 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.1 0.2 GO:0044878 mitotic cytokinesis checkpoint(GO:0044878)
0.1 0.5 GO:0034421 post-translational protein acetylation(GO:0034421)
0.1 0.9 GO:0034214 protein hexamerization(GO:0034214)
0.1 0.3 GO:0035247 peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918) peptidyl-arginine omega-N-methylation(GO:0035247)
0.1 0.3 GO:0071929 alpha-tubulin acetylation(GO:0071929)
0.1 0.5 GO:0018202 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183) peptidyl-histidine modification(GO:0018202)
0.1 1.1 GO:0002051 osteoblast fate commitment(GO:0002051)
0.1 0.6 GO:0090086 negative regulation of protein deubiquitination(GO:0090086)
0.1 0.7 GO:0015919 peroxisomal membrane transport(GO:0015919) protein import into peroxisome membrane(GO:0045046)
0.1 0.3 GO:0048611 ectodermal digestive tract development(GO:0007439) embryonic ectodermal digestive tract development(GO:0048611)
0.1 3.3 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.1 0.2 GO:1903371 regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.1 0.3 GO:0030472 mitotic spindle organization in nucleus(GO:0030472)
0.1 0.3 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.1 0.7 GO:0003431 growth plate cartilage chondrocyte development(GO:0003431)
0.1 0.5 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
0.1 0.6 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.1 1.3 GO:0051292 nuclear pore complex assembly(GO:0051292)
0.1 2.3 GO:0052646 alditol phosphate metabolic process(GO:0052646)
0.1 0.3 GO:0072385 minus-end-directed organelle transport along microtubule(GO:0072385)
0.1 4.0 GO:0031648 protein destabilization(GO:0031648)
0.1 0.3 GO:0006116 NADH oxidation(GO:0006116)
0.1 0.9 GO:0006002 fructose 6-phosphate metabolic process(GO:0006002)
0.1 4.5 GO:0030071 regulation of mitotic metaphase/anaphase transition(GO:0030071)
0.1 1.4 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617)
0.1 0.5 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.1 0.3 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.1 0.2 GO:0035246 peptidyl-arginine N-methylation(GO:0035246)
0.1 0.2 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.1 0.2 GO:0061324 canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation(GO:0061324) regulation of histone demethylase activity (H3-K4 specific)(GO:1904173) regulation of chromatin-mediated maintenance of transcription(GO:1904499) positive regulation of chromatin-mediated maintenance of transcription(GO:1904501) regulation of euchromatin binding(GO:1904793)
0.1 1.6 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.1 0.1 GO:0006114 glycerol biosynthetic process(GO:0006114) alditol biosynthetic process(GO:0019401)
0.1 0.4 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.1 0.7 GO:0061042 vascular wound healing(GO:0061042)
0.1 0.4 GO:0018343 protein farnesylation(GO:0018343)
0.1 0.4 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.1 0.1 GO:0019043 establishment of viral latency(GO:0019043)
0.1 0.1 GO:2000002 negative regulation of DNA damage checkpoint(GO:2000002)
0.1 0.2 GO:0036509 trimming of terminal mannose on B branch(GO:0036509) positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
0.1 0.5 GO:0075525 viral translational termination-reinitiation(GO:0075525)
0.1 0.2 GO:0035720 intraciliary anterograde transport(GO:0035720)
0.1 1.7 GO:0008210 estrogen metabolic process(GO:0008210)
0.1 0.6 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.1 0.4 GO:0040031 snRNA modification(GO:0040031)
0.1 1.3 GO:0035090 maintenance of apical/basal cell polarity(GO:0035090)
0.1 0.5 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.1 0.3 GO:0006772 thiamine metabolic process(GO:0006772) thiamine-containing compound metabolic process(GO:0042723)
0.1 0.5 GO:0016246 RNA interference(GO:0016246)
0.1 0.7 GO:0035360 positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360)
0.1 0.3 GO:0033159 negative regulation of protein import into nucleus, translocation(GO:0033159)
0.1 1.0 GO:0090435 protein localization to nuclear envelope(GO:0090435)
0.1 0.7 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.1 0.4 GO:0043097 pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
0.1 0.3 GO:0090521 glomerular visceral epithelial cell migration(GO:0090521)
0.1 4.3 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.1 1.3 GO:0019370 leukotriene biosynthetic process(GO:0019370)
0.1 0.4 GO:1900264 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.1 0.2 GO:0015811 L-cystine transport(GO:0015811)
0.1 0.7 GO:0035089 establishment of apical/basal cell polarity(GO:0035089)
0.1 0.1 GO:0046462 monoacylglycerol metabolic process(GO:0046462)
0.1 0.3 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.1 0.4 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.1 1.1 GO:0006337 nucleosome disassembly(GO:0006337)
0.1 0.2 GO:0034201 response to oleic acid(GO:0034201)
0.1 0.6 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
0.1 1.0 GO:0032402 melanosome transport(GO:0032402)
0.1 0.8 GO:0046498 S-adenosylhomocysteine metabolic process(GO:0046498)
0.1 0.3 GO:0044597 polyketide metabolic process(GO:0030638) aminoglycoside antibiotic metabolic process(GO:0030647) daunorubicin metabolic process(GO:0044597) doxorubicin metabolic process(GO:0044598)
0.1 1.6 GO:0043968 histone H2A acetylation(GO:0043968)
0.1 1.2 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.1 0.2 GO:0071051 U4 snRNA 3'-end processing(GO:0034475) polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.1 2.0 GO:0007602 phototransduction(GO:0007602)
0.1 3.4 GO:0007257 activation of JUN kinase activity(GO:0007257)
0.1 0.1 GO:1901069 guanosine-containing compound catabolic process(GO:1901069)
0.1 0.4 GO:0061734 parkin-mediated mitophagy in response to mitochondrial depolarization(GO:0061734)
0.1 1.0 GO:0046085 adenosine metabolic process(GO:0046085)
0.1 0.7 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.1 0.2 GO:0035928 rRNA import into mitochondrion(GO:0035928)
0.1 0.3 GO:0008616 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.1 0.8 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.1 1.3 GO:1902751 positive regulation of cell cycle G2/M phase transition(GO:1902751)
0.1 0.2 GO:0007571 age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571)
0.0 1.4 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.0 0.6 GO:0006415 translational termination(GO:0006415)
0.0 0.1 GO:0030961 peptidyl-arginine hydroxylation(GO:0030961)
0.0 0.2 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.0 0.3 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.0 0.4 GO:0071494 cellular response to UV-C(GO:0071494)
0.0 0.1 GO:0061339 establishment or maintenance of monopolar cell polarity(GO:0061339)
0.0 0.1 GO:0048822 enucleate erythrocyte development(GO:0048822)
0.0 0.3 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.0 0.2 GO:0038032 termination of G-protein coupled receptor signaling pathway(GO:0038032)
0.0 1.1 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 0.7 GO:0006622 protein targeting to lysosome(GO:0006622)
0.0 0.2 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.0 0.1 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.0 0.3 GO:0036265 RNA (guanine-N7)-methylation(GO:0036265)
0.0 0.3 GO:0031053 primary miRNA processing(GO:0031053)
0.0 0.6 GO:0090209 negative regulation of triglyceride metabolic process(GO:0090209)
0.0 0.6 GO:0002566 somatic diversification of immune receptors via somatic mutation(GO:0002566) somatic hypermutation of immunoglobulin genes(GO:0016446)
0.0 0.3 GO:0044789 modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
0.0 0.3 GO:0009642 response to light intensity(GO:0009642)
0.0 0.6 GO:0000212 meiotic spindle organization(GO:0000212)
0.0 0.2 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.0 0.2 GO:0046909 intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445)
0.0 0.4 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.0 0.9 GO:0006379 mRNA cleavage(GO:0006379)
0.0 0.3 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.0 0.1 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.0 3.8 GO:0016579 protein deubiquitination(GO:0016579)
0.0 0.3 GO:0042078 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.0 1.2 GO:0045724 positive regulation of cilium assembly(GO:0045724)
0.0 0.3 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.5 GO:0042407 cristae formation(GO:0042407)
0.0 0.6 GO:0000920 cell separation after cytokinesis(GO:0000920)
0.0 1.2 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.6 GO:1901663 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 1.2 GO:1902230 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
0.0 0.7 GO:0021670 lateral ventricle development(GO:0021670)
0.0 0.9 GO:0008299 isoprenoid biosynthetic process(GO:0008299)
0.0 0.4 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 1.6 GO:0042775 mitochondrial ATP synthesis coupled electron transport(GO:0042775)
0.0 0.2 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.0 2.9 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.0 0.4 GO:0071732 cellular response to nitric oxide(GO:0071732)
0.0 0.3 GO:0006032 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032) glucosamine-containing compound catabolic process(GO:1901072)
0.0 0.3 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.0 0.2 GO:0032377 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.0 0.0 GO:0072554 blood vessel lumenization(GO:0072554)
0.0 2.3 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 0.5 GO:0006107 oxaloacetate metabolic process(GO:0006107)
0.0 0.7 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.0 0.6 GO:0045910 negative regulation of DNA recombination(GO:0045910)
0.0 0.7 GO:0007398 ectoderm development(GO:0007398)
0.0 0.5 GO:0007035 vacuolar acidification(GO:0007035)
0.0 0.4 GO:0060340 positive regulation of type I interferon-mediated signaling pathway(GO:0060340)
0.0 0.3 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.2 GO:0010626 negative regulation of Schwann cell proliferation(GO:0010626)
0.0 0.9 GO:0006471 protein ADP-ribosylation(GO:0006471)
0.0 0.4 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.0 0.3 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 0.2 GO:0097577 intracellular sequestering of iron ion(GO:0006880) sequestering of iron ion(GO:0097577)
0.0 0.2 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
0.0 0.1 GO:0044829 positive regulation by host of viral genome replication(GO:0044829)
0.0 0.3 GO:0032308 positive regulation of prostaglandin secretion(GO:0032308)
0.0 0.2 GO:0000733 DNA strand renaturation(GO:0000733)
0.0 0.1 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.0 0.2 GO:2001032 regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
0.0 0.2 GO:0000042 protein targeting to Golgi(GO:0000042)
0.0 0.6 GO:0000154 rRNA modification(GO:0000154)
0.0 0.2 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.0 0.1 GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.0 0.5 GO:0070831 basement membrane assembly(GO:0070831)
0.0 0.0 GO:0010643 cell communication by chemical coupling(GO:0010643)
0.0 0.2 GO:0070127 tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.0 0.2 GO:0046602 regulation of mitotic centrosome separation(GO:0046602)
0.0 0.8 GO:0046470 phosphatidylcholine metabolic process(GO:0046470)
0.0 1.6 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0 0.0 GO:0006407 rRNA export from nucleus(GO:0006407)
0.0 0.2 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.1 GO:0034197 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.0 0.3 GO:0009191 ribonucleoside diphosphate catabolic process(GO:0009191)
0.0 0.2 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.0 0.6 GO:0006754 ATP biosynthetic process(GO:0006754)
0.0 0.6 GO:1901798 positive regulation of signal transduction by p53 class mediator(GO:1901798)
0.0 0.1 GO:0034080 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0 1.2 GO:0034605 cellular response to heat(GO:0034605)
0.0 0.3 GO:0000338 protein deneddylation(GO:0000338)
0.0 0.1 GO:1990592 protein ufmylation(GO:0071569) protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0 0.1 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.0 0.7 GO:0006879 cellular iron ion homeostasis(GO:0006879)
0.0 0.1 GO:0032375 regulation of intestinal cholesterol absorption(GO:0030300) negative regulation of sterol transport(GO:0032372) negative regulation of cholesterol transport(GO:0032375) negative regulation of intestinal absorption(GO:1904479)
0.0 0.2 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.0 0.1 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.0 0.1 GO:0045575 basophil activation involved in immune response(GO:0002276) basophil activation(GO:0045575)
0.0 0.6 GO:0048820 hair follicle maturation(GO:0048820)
0.0 0.3 GO:0033601 positive regulation of mammary gland epithelial cell proliferation(GO:0033601)
0.0 0.1 GO:0002759 regulation of antimicrobial humoral response(GO:0002759)
0.0 1.1 GO:0090305 nucleic acid phosphodiester bond hydrolysis(GO:0090305)
0.0 0.4 GO:0044458 motile cilium assembly(GO:0044458)
0.0 0.1 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.1 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.0 0.3 GO:0002176 male germ cell proliferation(GO:0002176)
0.0 0.7 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.0 0.7 GO:0043044 ATP-dependent chromatin remodeling(GO:0043044)
0.0 0.5 GO:0007530 sex determination(GO:0007530)
0.0 0.8 GO:0009268 response to pH(GO:0009268)
0.0 0.1 GO:1905171 protein localization to phagocytic vesicle(GO:1905161) regulation of protein localization to phagocytic vesicle(GO:1905169) positive regulation of protein localization to phagocytic vesicle(GO:1905171)
0.0 0.7 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 0.4 GO:0032967 positive regulation of collagen biosynthetic process(GO:0032967)
0.0 0.1 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.0 0.2 GO:0006103 2-oxoglutarate metabolic process(GO:0006103)
0.0 0.1 GO:1903232 melanosome assembly(GO:1903232)
0.0 0.3 GO:0015858 nucleoside transport(GO:0015858)
0.0 0.2 GO:0071450 removal of superoxide radicals(GO:0019430) cellular response to oxygen radical(GO:0071450) cellular response to superoxide(GO:0071451)
0.0 0.6 GO:0006400 tRNA modification(GO:0006400)
0.0 0.0 GO:0021555 midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.0 0.2 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.0 0.0 GO:0090076 relaxation of skeletal muscle(GO:0090076)
0.0 0.1 GO:0010820 positive regulation of T cell chemotaxis(GO:0010820)
0.0 0.3 GO:0048671 negative regulation of collateral sprouting(GO:0048671)
0.0 0.3 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.1 GO:0018126 protein hydroxylation(GO:0018126)
0.0 0.0 GO:0046103 inosine metabolic process(GO:0046102) inosine biosynthetic process(GO:0046103)
0.0 0.7 GO:0016925 protein sumoylation(GO:0016925)
0.0 0.2 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.0 0.2 GO:0090161 Golgi ribbon formation(GO:0090161)
0.0 0.2 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.2 GO:0051001 negative regulation of nitric-oxide synthase activity(GO:0051001)
0.0 0.4 GO:0046856 phosphatidylinositol dephosphorylation(GO:0046856)
0.0 0.0 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.0 0.2 GO:0071850 mitotic cell cycle arrest(GO:0071850)
0.0 0.3 GO:0051290 protein heterotetramerization(GO:0051290)
0.0 0.2 GO:0071361 cellular response to ethanol(GO:0071361)
0.0 1.1 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.0 0.0 GO:2000210 positive regulation of anoikis(GO:2000210)
0.0 0.1 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
0.0 0.8 GO:0046474 glycerophospholipid biosynthetic process(GO:0046474)
0.0 0.1 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 4.4 GO:0033597 mitotic checkpoint complex(GO:0033597) bub1-bub3 complex(GO:1990298)
0.9 5.5 GO:0070449 elongin complex(GO:0070449)
0.8 3.4 GO:0000438 core TFIIH complex portion of holo TFIIH complex(GO:0000438)
0.8 3.0 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.7 2.2 GO:0097361 CIA complex(GO:0097361)
0.7 6.2 GO:0070545 PeBoW complex(GO:0070545)
0.7 2.0 GO:1990423 RZZ complex(GO:1990423)
0.6 6.8 GO:0070578 micro-ribonucleoprotein complex(GO:0035068) RISC-loading complex(GO:0070578)
0.6 1.8 GO:1902560 GMP reductase complex(GO:1902560)
0.5 3.3 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.5 1.0 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.5 4.7 GO:0005787 signal peptidase complex(GO:0005787)
0.5 2.3 GO:0044614 nuclear pore cytoplasmic filaments(GO:0044614)
0.4 2.5 GO:0032133 chromosome passenger complex(GO:0032133)
0.4 2.3 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.4 1.1 GO:0018444 translation release factor complex(GO:0018444)
0.4 2.5 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.4 2.1 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
0.3 2.7 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.3 2.9 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.3 1.9 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.3 1.0 GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.3 5.0 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.3 3.7 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.3 1.7 GO:0031262 Ndc80 complex(GO:0031262)
0.3 4.4 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.3 0.3 GO:1903349 omegasome membrane(GO:1903349)
0.2 0.9 GO:0017133 mitochondrial electron transfer flavoprotein complex(GO:0017133) electron transfer flavoprotein complex(GO:0045251)
0.2 1.6 GO:0005638 lamin filament(GO:0005638)
0.2 1.1 GO:1990745 EARP complex(GO:1990745)
0.2 1.9 GO:0045261 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.2 2.9 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.2 2.6 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.2 0.6 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.2 1.2 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.2 0.6 GO:0005673 transcription factor TFIIE complex(GO:0005673)
0.2 0.8 GO:0090661 box H/ACA telomerase RNP complex(GO:0090661)
0.2 0.5 GO:0055087 Ski complex(GO:0055087)
0.2 1.2 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.2 0.7 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.2 0.5 GO:0070557 PCNA-p21 complex(GO:0070557)
0.2 3.0 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.2 2.0 GO:0000778 condensed nuclear chromosome kinetochore(GO:0000778)
0.1 2.8 GO:0016580 Sin3 complex(GO:0016580)
0.1 1.8 GO:0070765 gamma-secretase complex(GO:0070765)
0.1 0.6 GO:0070822 Sin3-type complex(GO:0070822)
0.1 0.4 GO:0001739 sex chromatin(GO:0001739)
0.1 2.2 GO:0000124 SAGA complex(GO:0000124)
0.1 1.0 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.1 2.7 GO:0005640 nuclear outer membrane(GO:0005640)
0.1 0.4 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.1 0.6 GO:0035339 SPOTS complex(GO:0035339)
0.1 2.2 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.1 1.0 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.1 0.7 GO:0034709 methylosome(GO:0034709)
0.1 0.5 GO:0043259 laminin-1 complex(GO:0005606) laminin-10 complex(GO:0043259)
0.1 0.3 GO:0071001 U4/U6 snRNP(GO:0071001)
0.1 0.7 GO:0031166 integral component of vacuolar membrane(GO:0031166) intrinsic component of vacuolar membrane(GO:0031310)
0.1 1.3 GO:0005687 U4 snRNP(GO:0005687)
0.1 0.8 GO:0030689 Noc complex(GO:0030689)
0.1 0.8 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.1 1.4 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.1 1.0 GO:0070652 HAUS complex(GO:0070652)
0.1 0.7 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.1 1.3 GO:0000815 ESCRT III complex(GO:0000815)
0.1 0.6 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.1 0.5 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.1 0.5 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.1 0.3 GO:0070876 SOSS complex(GO:0070876)
0.1 0.3 GO:0070877 microprocessor complex(GO:0070877) ribonuclease III complex(GO:1903095)
0.1 0.7 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.1 0.3 GO:0098842 postsynaptic early endosome(GO:0098842)
0.1 1.3 GO:0005869 dynactin complex(GO:0005869)
0.1 0.6 GO:0044611 nuclear pore inner ring(GO:0044611)
0.1 1.0 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.1 0.3 GO:0044302 dentate gyrus mossy fiber(GO:0044302)
0.1 1.4 GO:0035631 CD40 receptor complex(GO:0035631)
0.1 0.5 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1 1.6 GO:0035102 PRC1 complex(GO:0035102)
0.1 1.1 GO:0000813 ESCRT I complex(GO:0000813)
0.1 0.9 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.1 0.8 GO:0001940 male pronucleus(GO:0001940)
0.1 6.8 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.1 0.4 GO:0005945 6-phosphofructokinase complex(GO:0005945)
0.1 0.6 GO:0033263 CORVET complex(GO:0033263)
0.1 1.1 GO:0071203 WASH complex(GO:0071203)
0.1 0.1 GO:0005838 proteasome regulatory particle(GO:0005838)
0.1 0.5 GO:0061617 MICOS complex(GO:0061617)
0.1 3.6 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.1 0.4 GO:0071256 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.1 0.6 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.1 0.5 GO:0005686 U2 snRNP(GO:0005686)
0.1 1.1 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.1 0.7 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.1 1.2 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229) nuclear membrane part(GO:0044453)
0.1 0.6 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 1.2 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.1 0.6 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.1 4.6 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 2.7 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.1 0.5 GO:0042382 paraspeckles(GO:0042382)
0.1 13.6 GO:0005759 mitochondrial matrix(GO:0005759)
0.1 0.9 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.1 2.6 GO:0015030 Cajal body(GO:0015030)
0.1 0.3 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 0.1 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.0 0.6 GO:0030867 rough endoplasmic reticulum membrane(GO:0030867)
0.0 1.3 GO:0031305 integral component of mitochondrial inner membrane(GO:0031305)
0.0 0.5 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 2.1 GO:0030964 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.0 GO:1902737 dendritic filopodium(GO:1902737)
0.0 0.5 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.2 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.0 1.1 GO:0051233 spindle midzone(GO:0051233)
0.0 2.0 GO:0035861 site of double-strand break(GO:0035861)
0.0 5.7 GO:0031526 brush border membrane(GO:0031526)
0.0 1.3 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 0.1 GO:0034455 t-UTP complex(GO:0034455)
0.0 0.5 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.3 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 3.2 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 0.4 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.0 0.3 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.0 0.2 GO:0089701 U2AF(GO:0089701)
0.0 0.4 GO:0045298 tubulin complex(GO:0045298)
0.0 0.7 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.2 GO:0016461 unconventional myosin complex(GO:0016461)
0.0 0.7 GO:0071004 U2-type prespliceosome(GO:0071004)
0.0 0.5 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.2 GO:0002142 stereocilia ankle link complex(GO:0002142)
0.0 2.9 GO:0005643 nuclear pore(GO:0005643)
0.0 0.1 GO:0042575 DNA polymerase complex(GO:0042575)
0.0 1.7 GO:0060077 inhibitory synapse(GO:0060077)
0.0 3.5 GO:0000784 nuclear chromosome, telomeric region(GO:0000784)
0.0 2.2 GO:0045171 intercellular bridge(GO:0045171)
0.0 0.2 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 1.2 GO:0031306 intrinsic component of mitochondrial outer membrane(GO:0031306)
0.0 0.7 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 1.2 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 1.8 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.2 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.0 0.9 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.6 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.4 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.2 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.0 1.6 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.9 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.1 GO:0034657 GID complex(GO:0034657)
0.0 0.4 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.2 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.0 2.0 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.1 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.0 1.0 GO:0031461 cullin-RING ubiquitin ligase complex(GO:0031461)
0.0 0.7 GO:0030904 retromer complex(GO:0030904)
0.0 0.7 GO:0043596 nuclear replication fork(GO:0043596)
0.0 0.3 GO:0030126 COPI vesicle coat(GO:0030126) COPI-coated vesicle membrane(GO:0030663)
0.0 0.6 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.1 GO:0005818 aster(GO:0005818)
0.0 0.4 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.6 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.6 GO:0005779 integral component of peroxisomal membrane(GO:0005779)
0.0 0.3 GO:0031932 TORC2 complex(GO:0031932)
0.0 3.7 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 0.1 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0 0.5 GO:0070938 contractile ring(GO:0070938)
0.0 1.1 GO:0005778 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.2 GO:0005845 mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.0 0.8 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 2.0 GO:0000776 kinetochore(GO:0000776)
0.0 0.2 GO:0031415 NatA complex(GO:0031415)
0.0 1.0 GO:0008180 COP9 signalosome(GO:0008180)
0.0 1.6 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.2 GO:0000812 Swr1 complex(GO:0000812)
0.0 0.6 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.0 0.1 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.0 0.1 GO:0044352 pinosome(GO:0044352) macropinosome(GO:0044354)
0.0 0.1 GO:0042587 glycogen granule(GO:0042587)
0.0 3.6 GO:0005769 early endosome(GO:0005769)
0.0 0.1 GO:0000796 condensin complex(GO:0000796)
0.0 0.3 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.0 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.0 0.8 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 0.4 GO:0005771 multivesicular body(GO:0005771)
0.0 3.0 GO:0000139 Golgi membrane(GO:0000139)
0.0 0.6 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.7 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.9 GO:0000922 spindle pole(GO:0000922)
0.0 0.2 GO:0034464 BBSome(GO:0034464)
0.0 0.2 GO:0044754 autolysosome(GO:0044754)
0.0 1.3 GO:0032587 ruffle membrane(GO:0032587)
0.0 17.7 GO:0005783 endoplasmic reticulum(GO:0005783)
0.0 0.7 GO:0010494 cytoplasmic stress granule(GO:0010494)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.7 6.6 GO:0004337 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
1.6 4.9 GO:0004823 glutamine-tRNA ligase activity(GO:0004819) leucine-tRNA ligase activity(GO:0004823)
0.9 2.6 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.9 3.4 GO:0004793 threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.9 6.8 GO:0070883 pre-miRNA binding(GO:0070883)
0.8 3.0 GO:0030549 acetylcholine receptor activator activity(GO:0030549)
0.7 2.9 GO:0000702 oxidized base lesion DNA N-glycosylase activity(GO:0000702)
0.6 1.9 GO:0052642 lysophosphatidic acid phosphatase activity(GO:0052642)
0.6 1.8 GO:0016657 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.6 1.8 GO:0017099 very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099)
0.6 3.4 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.5 1.6 GO:0016034 maleylacetoacetate isomerase activity(GO:0016034)
0.5 3.3 GO:0046404 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.5 1.6 GO:0035175 histone kinase activity (H3-S10 specific)(GO:0035175)
0.5 3.1 GO:0008518 reduced folate carrier activity(GO:0008518)
0.5 1.5 GO:0005457 GDP-fucose transmembrane transporter activity(GO:0005457) purine nucleotide-sugar transmembrane transporter activity(GO:0036080)
0.5 2.5 GO:0017108 5'-flap endonuclease activity(GO:0017108)
0.5 2.4 GO:0001032 RNA polymerase III type 3 promoter DNA binding(GO:0001032)
0.4 1.7 GO:0050252 retinol O-fatty-acyltransferase activity(GO:0050252)
0.4 2.0 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
0.4 2.0 GO:0047635 L-alanine:2-oxoglutarate aminotransferase activity(GO:0004021) alanine-oxo-acid transaminase activity(GO:0047635)
0.4 2.5 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.3 0.7 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.3 1.0 GO:0016900 oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
0.3 1.0 GO:0030943 mitochondrion targeting sequence binding(GO:0030943)
0.3 1.0 GO:0030622 U4atac snRNA binding(GO:0030622)
0.3 1.6 GO:0032767 copper-dependent protein binding(GO:0032767)
0.3 1.0 GO:0050567 glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
0.3 2.0 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.3 0.6 GO:0048256 flap endonuclease activity(GO:0048256)
0.3 2.0 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.3 3.1 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.3 0.9 GO:0000171 ribonuclease MRP activity(GO:0000171)
0.3 1.3 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.2 3.5 GO:0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.2 0.7 GO:0003896 DNA primase activity(GO:0003896)
0.2 1.1 GO:0003880 protein C-terminal carboxyl O-methyltransferase activity(GO:0003880)
0.2 2.9 GO:0001054 RNA polymerase I activity(GO:0001054)
0.2 1.3 GO:0004594 pantothenate kinase activity(GO:0004594)
0.2 1.3 GO:0005047 signal recognition particle binding(GO:0005047)
0.2 0.6 GO:0008396 oxysterol 7-alpha-hydroxylase activity(GO:0008396)
0.2 0.6 GO:0004774 succinate-CoA ligase activity(GO:0004774)
0.2 1.6 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.2 0.6 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.2 0.6 GO:0016781 selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
0.2 0.9 GO:0016649 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.2 0.7 GO:1990932 5.8S rRNA binding(GO:1990932)
0.2 2.0 GO:0019104 DNA N-glycosylase activity(GO:0019104)
0.2 1.2 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.2 1.0 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.2 1.7 GO:0050733 RS domain binding(GO:0050733)
0.2 0.5 GO:0033149 FFAT motif binding(GO:0033149)
0.2 0.3 GO:0030621 U4 snRNA binding(GO:0030621)
0.2 4.1 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.2 3.1 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.2 1.3 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.2 1.3 GO:0000403 Y-form DNA binding(GO:0000403)
0.2 0.6 GO:0004127 cytidylate kinase activity(GO:0004127) uridylate kinase activity(GO:0009041) nucleoside phosphate kinase activity(GO:0050145)
0.2 1.4 GO:0070567 cytidylyltransferase activity(GO:0070567)
0.2 0.9 GO:0044020 histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.2 0.5 GO:0008988 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179) rRNA (adenine-N6-)-methyltransferase activity(GO:0008988)
0.2 0.6 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.1 1.5 GO:0036310 annealing helicase activity(GO:0036310)
0.1 2.1 GO:0008106 alcohol dehydrogenase (NADP+) activity(GO:0008106)
0.1 0.4 GO:0004019 adenylosuccinate synthase activity(GO:0004019)
0.1 0.7 GO:0097003 adipokinetic hormone receptor activity(GO:0097003)
0.1 1.3 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.1 6.4 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.1 3.6 GO:0097602 cullin family protein binding(GO:0097602)
0.1 0.4 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.1 0.9 GO:0004526 ribonuclease P activity(GO:0004526)
0.1 2.2 GO:1990226 histone methyltransferase binding(GO:1990226)
0.1 1.9 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.1 1.1 GO:0000150 recombinase activity(GO:0000150)
0.1 0.6 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.1 0.5 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.1 0.9 GO:0034452 dynactin binding(GO:0034452)
0.1 2.4 GO:0010181 FMN binding(GO:0010181)
0.1 0.8 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.1 0.3 GO:0004613 phosphoenolpyruvate carboxykinase activity(GO:0004611) phosphoenolpyruvate carboxykinase (GTP) activity(GO:0004613)
0.1 0.8 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.1 1.1 GO:0097322 7SK snRNA binding(GO:0097322)
0.1 1.1 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.1 1.9 GO:0003688 DNA replication origin binding(GO:0003688)
0.1 5.3 GO:0008536 Ran GTPase binding(GO:0008536)
0.1 2.1 GO:0005537 mannose binding(GO:0005537)
0.1 1.8 GO:0015037 peptide disulfide oxidoreductase activity(GO:0015037)
0.1 0.5 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.1 0.6 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.1 4.0 GO:0070064 proline-rich region binding(GO:0070064)
0.1 0.3 GO:0016508 long-chain-enoyl-CoA hydratase activity(GO:0016508)
0.1 0.9 GO:0000182 rDNA binding(GO:0000182)
0.1 0.2 GO:0098808 mRNA cap binding(GO:0098808)
0.1 1.8 GO:0042288 MHC class I protein binding(GO:0042288)
0.1 0.5 GO:0031781 melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.1 1.4 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.1 0.3 GO:0036004 GAF domain binding(GO:0036004)
0.1 3.7 GO:0001671 ATPase activator activity(GO:0001671)
0.1 0.7 GO:0035184 histone threonine kinase activity(GO:0035184)
0.1 9.4 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.1 1.0 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.1 3.5 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.1 0.6 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.1 1.5 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.1 0.2 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.1 1.1 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.1 0.4 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.1 0.4 GO:0003872 6-phosphofructokinase activity(GO:0003872)
0.1 0.2 GO:0001096 TFIIF-class transcription factor binding(GO:0001096)
0.1 0.3 GO:0032296 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.1 0.5 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.1 0.3 GO:0047522 13-prostaglandin reductase activity(GO:0036132) 15-oxoprostaglandin 13-oxidase activity(GO:0047522)
0.1 0.3 GO:0008160 protein tyrosine phosphatase activator activity(GO:0008160)
0.1 0.4 GO:0004849 uridine kinase activity(GO:0004849)
0.1 3.3 GO:0031369 translation initiation factor binding(GO:0031369)
0.1 0.3 GO:0030620 U2 snRNA binding(GO:0030620)
0.1 0.6 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.1 0.6 GO:0016892 endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892)
0.1 2.3 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.1 0.2 GO:0016426 tRNA (adenine) methyltransferase activity(GO:0016426)
0.1 1.6 GO:0051400 BH domain binding(GO:0051400)
0.1 0.3 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.1 0.2 GO:0015184 L-cystine transmembrane transporter activity(GO:0015184)
0.1 0.2 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.1 5.9 GO:0008565 protein transporter activity(GO:0008565)
0.1 2.9 GO:0033558 protein deacetylase activity(GO:0033558)
0.1 0.4 GO:0008172 S-methyltransferase activity(GO:0008172)
0.1 0.8 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656) protein phosphatase 2B binding(GO:0030346)
0.1 0.1 GO:0097642 calcitonin family receptor activity(GO:0097642)
0.1 0.7 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.1 0.2 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.1 0.9 GO:0017049 GTP-Rho binding(GO:0017049)
0.1 1.5 GO:0017025 TBP-class protein binding(GO:0017025)
0.1 0.5 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.1 0.3 GO:0004382 guanosine-diphosphatase activity(GO:0004382)
0.1 0.1 GO:0031493 nucleosomal histone binding(GO:0031493)
0.1 0.8 GO:0031386 protein tag(GO:0031386)
0.1 0.5 GO:0043208 glycosphingolipid binding(GO:0043208)
0.0 2.0 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.2 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.0 1.0 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.3 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.0 0.7 GO:0015368 calcium:cation antiporter activity(GO:0015368)
0.0 0.3 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.0 0.7 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.1 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 0.5 GO:0070034 telomerase RNA binding(GO:0070034)
0.0 0.6 GO:0019213 deacetylase activity(GO:0019213)
0.0 0.1 GO:0003846 2-acylglycerol O-acyltransferase activity(GO:0003846)
0.0 0.3 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 0.4 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.3 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.0 0.7 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.7 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.0 0.8 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.3 GO:0032027 myosin light chain binding(GO:0032027)
0.0 0.1 GO:0044715 8-oxo-dGDP phosphatase activity(GO:0044715)
0.0 0.1 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.0 0.1 GO:0031544 peptidyl-proline 3-dioxygenase activity(GO:0031544)
0.0 1.4 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.4 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.7 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.3 GO:1990446 U1 snRNP binding(GO:1990446)
0.0 0.4 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.0 0.7 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.4 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.0 0.8 GO:0004622 lysophospholipase activity(GO:0004622)
0.0 0.3 GO:0004568 chitinase activity(GO:0004568)
0.0 0.8 GO:0003954 NADH dehydrogenase activity(GO:0003954)
0.0 2.1 GO:0019843 rRNA binding(GO:0019843)
0.0 0.7 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.4 GO:0048038 quinone binding(GO:0048038)
0.0 1.0 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.0 3.3 GO:0043130 ubiquitin binding(GO:0043130)
0.0 0.2 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 1.6 GO:0016811 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides(GO:0016811)
0.0 0.3 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0 0.1 GO:0008967 phosphoglycolate phosphatase activity(GO:0008967)
0.0 1.6 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 2.0 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.4 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.0 1.7 GO:0008186 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004) RNA-dependent ATPase activity(GO:0008186)
0.0 0.1 GO:0030375 thyroid hormone receptor coactivator activity(GO:0030375)
0.0 0.3 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 0.0 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.0 0.1 GO:0001729 ceramide kinase activity(GO:0001729)
0.0 1.1 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.3 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 3.5 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.2 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 0.3 GO:0008417 fucosyltransferase activity(GO:0008417)
0.0 0.2 GO:0052655 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.0 5.6 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 1.6 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.0 0.4 GO:0036459 thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 0.5 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.5 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.1 GO:0035650 AP-1 adaptor complex binding(GO:0035650) BLOC-2 complex binding(GO:0036461)
0.0 1.0 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors(GO:0016627)
0.0 0.1 GO:0032453 histone demethylase activity (H3-K4 specific)(GO:0032453)
0.0 1.1 GO:0019003 GDP binding(GO:0019003)
0.0 0.1 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 0.5 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.0 0.2 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 1.0 GO:0050699 WW domain binding(GO:0050699)
0.0 0.3 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.0 GO:0000099 sulfur amino acid transmembrane transporter activity(GO:0000099)
0.0 0.2 GO:0046527 glucosyltransferase activity(GO:0046527)
0.0 2.7 GO:0000149 SNARE binding(GO:0000149)
0.0 0.2 GO:0016864 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.2 GO:0050072 m7G(5')pppN diphosphatase activity(GO:0050072)
0.0 0.3 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 9.4 GO:0008233 peptidase activity(GO:0008233)
0.0 0.1 GO:0004565 beta-galactosidase activity(GO:0004565)
0.0 8.3 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 0.1 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.2 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.0 GO:0032217 riboflavin transporter activity(GO:0032217)
0.0 0.2 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.6 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.1 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.3 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 1.0 GO:0015078 hydrogen ion transmembrane transporter activity(GO:0015078)
0.0 1.1 GO:0043621 protein self-association(GO:0043621)
0.0 0.4 GO:0043394 proteoglycan binding(GO:0043394)
0.0 0.1 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.1 GO:0034185 apolipoprotein binding(GO:0034185)
0.0 0.3 GO:0004521 endoribonuclease activity(GO:0004521)
0.0 0.2 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.2 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.4 GO:0051721 protein phosphatase 2A binding(GO:0051721)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.5 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1 2.2 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1 2.3 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.1 5.1 PID AURORA A PATHWAY Aurora A signaling
0.1 5.4 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.1 1.8 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.1 3.4 PID ATR PATHWAY ATR signaling pathway
0.1 1.2 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 3.0 PID EPHA FWDPATHWAY EPHA forward signaling
0.1 0.7 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.1 1.6 PID ARF 3PATHWAY Arf1 pathway
0.0 1.2 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.8 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 1.6 PID AURORA B PATHWAY Aurora B signaling
0.0 2.3 PID PLK1 PATHWAY PLK1 signaling events
0.0 3.4 PID P73PATHWAY p73 transcription factor network
0.0 0.5 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 1.6 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.7 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 1.7 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.7 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 2.3 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 1.4 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 0.3 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.6 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.8 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.2 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 0.1 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 0.2 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 0.3 PID BARD1 PATHWAY BARD1 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 6.2 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.3 7.9 REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A Genes involved in APC-Cdc20 mediated degradation of Nek2A
0.3 7.2 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.2 6.1 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.2 5.6 REACTOME RESOLUTION OF AP SITES VIA THE MULTIPLE NUCLEOTIDE PATCH REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the multiple-nucleotide patch replacement pathway
0.2 4.7 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.2 6.6 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.2 2.5 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.2 0.3 REACTOME MRNA CAPPING Genes involved in mRNA Capping
0.2 5.2 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.2 2.0 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.2 3.5 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.1 0.9 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.1 1.6 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.1 3.3 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.1 3.0 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.1 0.1 REACTOME PHOSPHORYLATION OF THE APC C Genes involved in Phosphorylation of the APC/C
0.1 0.7 REACTOME PROCESSIVE SYNTHESIS ON THE LAGGING STRAND Genes involved in Processive synthesis on the lagging strand
0.1 1.8 REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS Genes involved in NRIF signals cell death from the nucleus
0.1 10.6 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.1 1.6 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.1 1.6 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.1 4.9 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.1 2.1 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.1 5.4 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.1 2.4 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.1 0.7 REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES Genes involved in p75NTR recruits signalling complexes
0.1 2.5 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.1 1.0 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.1 0.2 REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
0.1 1.8 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.1 2.0 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.1 1.1 REACTOME REGULATION OF APOPTOSIS Genes involved in Regulation of Apoptosis
0.1 1.5 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.1 0.2 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.1 3.0 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.1 7.9 REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.1 1.0 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.1 1.0 REACTOME RNA POL I TRANSCRIPTION Genes involved in RNA Polymerase I Transcription
0.0 2.1 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 2.4 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 1.1 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.4 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 3.2 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 1.6 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.6 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.6 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 1.3 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.6 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 1.0 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.6 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 1.2 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 2.5 REACTOME TRIGLYCERIDE BIOSYNTHESIS Genes involved in Triglyceride Biosynthesis
0.0 1.1 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.4 REACTOME ASSEMBLY OF THE PRE REPLICATIVE COMPLEX Genes involved in Assembly of the pre-replicative complex
0.0 1.5 REACTOME POST TRANSLATIONAL MODIFICATION SYNTHESIS OF GPI ANCHORED PROTEINS Genes involved in Post-translational modification: synthesis of GPI-anchored proteins
0.0 0.1 REACTOME P53 INDEPENDENT G1 S DNA DAMAGE CHECKPOINT Genes involved in p53-Independent G1/S DNA damage checkpoint
0.0 0.9 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.0 0.4 REACTOME MITOTIC M M G1 PHASES Genes involved in Mitotic M-M/G1 phases
0.0 0.5 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.0 0.5 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.4 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.3 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.0 1.1 REACTOME TRANSLATION Genes involved in Translation
0.0 0.3 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 1.2 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0 0.3 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 1.2 REACTOME GOLGI ASSOCIATED VESICLE BIOGENESIS Genes involved in Golgi Associated Vesicle Biogenesis
0.0 0.4 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.1 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.2 REACTOME P53 DEPENDENT G1 DNA DAMAGE RESPONSE Genes involved in p53-Dependent G1 DNA Damage Response
0.0 0.1 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 1.6 REACTOME APOPTOTIC EXECUTION PHASE Genes involved in Apoptotic execution phase
0.0 0.3 REACTOME HOST INTERACTIONS OF HIV FACTORS Genes involved in Host Interactions of HIV factors
0.0 0.4 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.4 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.6 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.9 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.0 1.6 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 0.4 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0 0.3 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.3 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.2 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.0 0.2 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.0 0.3 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.2 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.0 0.1 REACTOME PRE NOTCH EXPRESSION AND PROCESSING Genes involved in Pre-NOTCH Expression and Processing
0.0 0.3 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.7 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling