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avrg: 2D miR_HR1_12
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Results for Atf6
Z-value: 4.26
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Transcription factors associated with Atf6
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Atf6 | mm10_v2_chr1_-_170867761_170867784 | -0.31 | 3.2e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr8_-_90908415 Show fit | 8.22 |
ENSMUST00000098517.1
|
predicted gene 6658 |
|
| chr5_+_137288273 Show fit | 5.28 |
ENSMUST00000024099.4
ENSMUST00000085934.3 |
acetylcholinesterase |
|
| chr8_-_70487314 Show fit | 4.36 |
ENSMUST00000045286.7
|
transmembrane protein 59-like |
|
| chr7_-_45092130 Show fit | 4.21 |
ENSMUST00000148175.1
|
reticulocalbin 3, EF-hand calcium binding domain |
|
| chr11_+_69991061 Show fit | 4.02 |
ENSMUST00000018711.8
|
gamma-aminobutyric acid receptor associated protein |
|
| chr7_-_45091713 Show fit | 3.73 |
ENSMUST00000141576.1
|
reticulocalbin 3, EF-hand calcium binding domain |
|
| chr10_-_81291227 Show fit | 3.61 |
ENSMUST00000045744.6
|
tight junction protein 3 |
|
| chr5_+_35056813 Show fit | 3.57 |
ENSMUST00000101298.2
ENSMUST00000114270.1 ENSMUST00000133381.1 |
docking protein 7 |
|
| chr17_-_67354459 Show fit | 3.53 |
ENSMUST00000037974.8
|
protein tyrosine phosphatase, receptor type, M |
|
| chr9_+_72925622 Show fit | 3.46 |
ENSMUST00000038489.5
|
pygopus 1 |
Network of associatons between targets according to the STRING database.
First level regulatory network of Atf6
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 9.5 | GO:0006506 | GPI anchor biosynthetic process(GO:0006506) |
| 1.1 | 8.0 | GO:0019695 | choline metabolic process(GO:0019695) |
| 0.4 | 7.6 | GO:0071577 | zinc II ion transmembrane transport(GO:0071577) |
| 0.7 | 6.7 | GO:0090166 | Golgi disassembly(GO:0090166) |
| 0.1 | 6.3 | GO:0061098 | positive regulation of protein tyrosine kinase activity(GO:0061098) |
| 0.7 | 6.1 | GO:0071569 | protein ufmylation(GO:0071569) |
| 0.1 | 4.9 | GO:0051591 | response to cAMP(GO:0051591) |
| 0.4 | 4.8 | GO:0006995 | cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562) |
| 0.6 | 4.3 | GO:0006621 | protein retention in ER lumen(GO:0006621) |
| 0.4 | 4.2 | GO:0048280 | vesicle fusion with Golgi apparatus(GO:0048280) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 23.1 | GO:0005783 | endoplasmic reticulum(GO:0005783) |
| 0.6 | 9.5 | GO:0000506 | glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506) |
| 0.6 | 7.5 | GO:0043083 | synaptic cleft(GO:0043083) |
| 0.1 | 6.7 | GO:0005801 | cis-Golgi network(GO:0005801) |
| 0.1 | 6.7 | GO:0031594 | neuromuscular junction(GO:0031594) |
| 0.3 | 6.4 | GO:0012507 | ER to Golgi transport vesicle membrane(GO:0012507) |
| 0.2 | 4.8 | GO:0000421 | autophagosome membrane(GO:0000421) |
| 0.4 | 4.1 | GO:0001739 | sex chromatin(GO:0001739) |
| 0.1 | 3.4 | GO:0031201 | SNARE complex(GO:0031201) |
| 0.0 | 3.3 | GO:0005913 | cell-cell adherens junction(GO:0005913) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.9 | 9.5 | GO:0017176 | phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176) |
| 0.3 | 9.3 | GO:0005385 | zinc ion transmembrane transporter activity(GO:0005385) |
| 2.0 | 8.0 | GO:0004104 | cholinesterase activity(GO:0004104) |
| 0.0 | 6.8 | GO:0005509 | calcium ion binding(GO:0005509) |
| 0.1 | 6.7 | GO:0005158 | insulin receptor binding(GO:0005158) |
| 0.1 | 5.0 | GO:0019905 | syntaxin binding(GO:0019905) |
| 0.1 | 4.9 | GO:0005484 | SNAP receptor activity(GO:0005484) |
| 1.1 | 4.3 | GO:0046923 | ER retention sequence binding(GO:0046923) |
| 0.2 | 4.1 | GO:0097371 | MDM2/MDM4 family protein binding(GO:0097371) |
| 0.2 | 4.0 | GO:0050811 | GABA receptor binding(GO:0050811) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 7.3 | PID ATF2 PATHWAY | ATF-2 transcription factor network |
| 0.2 | 6.8 | PID ARF 3PATHWAY | Arf1 pathway |
| 0.1 | 4.2 | PID TCR CALCIUM PATHWAY | Calcium signaling in the CD4+ TCR pathway |
| 0.1 | 3.4 | ST G ALPHA S PATHWAY | G alpha s Pathway |
| 0.1 | 3.3 | PID NECTIN PATHWAY | Nectin adhesion pathway |
| 0.0 | 2.3 | PID BMP PATHWAY | BMP receptor signaling |
| 0.0 | 2.2 | PID TRKR PATHWAY | Neurotrophic factor-mediated Trk receptor signaling |
| 0.1 | 2.0 | PID ERBB NETWORK PATHWAY | ErbB receptor signaling network |
| 0.0 | 1.8 | PID HDAC CLASSII PATHWAY | Signaling events mediated by HDAC Class II |
| 0.0 | 1.8 | PID PLK1 PATHWAY | PLK1 signaling events |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 9.5 | REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI | Genes involved in Synthesis of glycosylphosphatidylinositol (GPI) |
| 0.3 | 8.5 | REACTOME SYNTHESIS OF PC | Genes involved in Synthesis of PC |
| 0.1 | 6.8 | REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S | Genes involved in Activation of Chaperone Genes by XBP1(S) |
| 0.3 | 6.3 | REACTOME ZINC TRANSPORTERS | Genes involved in Zinc transporters |
| 0.0 | 3.8 | REACTOME SIGNALING BY RHO GTPASES | Genes involved in Signaling by Rho GTPases |
| 0.3 | 3.5 | REACTOME COPI MEDIATED TRANSPORT | Genes involved in COPI Mediated Transport |
| 0.1 | 2.9 | REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS | Genes involved in Trafficking of GluR2-containing AMPA receptors |
| 0.0 | 2.8 | REACTOME PEPTIDE LIGAND BINDING RECEPTORS | Genes involved in Peptide ligand-binding receptors |
| 0.1 | 2.7 | REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR | Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor |
| 0.0 | 1.9 | REACTOME VOLTAGE GATED POTASSIUM CHANNELS | Genes involved in Voltage gated Potassium channels |