Project
avrg: 2D miR_HR1_12
Navigation
Downloads
Results for Elf1_Elf2_Etv2_Elf4
Z-value: 3.67
Motif logo
Transcription factors associated with Elf1_Elf2_Etv2_Elf4
| Gene Symbol | Gene ID | Gene Info |
|---|---|---|
| ENSMUSG00000036461.9 | E74-like factor 1 | |
| ENSMUSG00000037174.12 | E74-like factor 2 | |
| ENSMUSG00000006311.8 | ets variant 2 | |
| ENSMUSG00000031103.6 | E74-like factor 4 (ets domain transcription factor) |
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Elf2 | mm10_v2_chr3_-_51277470_51277514 | 0.76 | 3.9e-03 | Click! |
| Elf1 | mm10_v2_chr14_+_79481164_79481194 | 0.37 | 2.4e-01 | Click! |
| Elf4 | mm10_v2_chrX_-_48454152_48454193 | -0.01 | 9.7e-01 | Click! |
Network of associatons between targets according to the STRING database.
First level regulatory network of Elf1_Elf2_Etv2_Elf4
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.6 | 39.3 | GO:0042273 | ribosomal large subunit biogenesis(GO:0042273) |
| 0.3 | 26.2 | GO:0042254 | ribosome biogenesis(GO:0042254) |
| 0.8 | 17.1 | GO:0000028 | ribosomal small subunit assembly(GO:0000028) |
| 0.2 | 15.4 | GO:0006413 | translational initiation(GO:0006413) |
| 0.1 | 15.2 | GO:0006412 | translation(GO:0006412) |
| 0.8 | 15.1 | GO:0051988 | regulation of attachment of spindle microtubules to kinetochore(GO:0051988) |
| 0.4 | 14.7 | GO:0002181 | cytoplasmic translation(GO:0002181) |
| 0.1 | 14.4 | GO:0000377 | RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398) |
| 0.4 | 13.3 | GO:0060236 | regulation of mitotic spindle organization(GO:0060236) |
| 0.1 | 12.8 | GO:0051028 | mRNA transport(GO:0051028) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 62.1 | GO:0005730 | nucleolus(GO:0005730) |
| 0.7 | 52.3 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
| 0.7 | 37.0 | GO:0022627 | cytosolic small ribosomal subunit(GO:0022627) |
| 0.2 | 22.3 | GO:0071013 | catalytic step 2 spliceosome(GO:0071013) |
| 0.6 | 18.9 | GO:0030687 | preribosome, large subunit precursor(GO:0030687) |
| 0.0 | 18.6 | GO:0005694 | chromosome(GO:0005694) |
| 0.6 | 17.5 | GO:0032040 | small-subunit processome(GO:0032040) |
| 0.3 | 16.3 | GO:0015934 | large ribosomal subunit(GO:0015934) |
| 0.4 | 13.8 | GO:0035371 | microtubule plus-end(GO:0035371) |
| 0.3 | 13.4 | GO:0005871 | kinesin complex(GO:0005871) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.5 | 76.6 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
| 0.1 | 70.6 | GO:0003723 | RNA binding(GO:0003723) |
| 0.4 | 27.4 | GO:0003743 | translation initiation factor activity(GO:0003743) |
| 0.1 | 20.1 | GO:0042393 | histone binding(GO:0042393) |
| 1.1 | 15.8 | GO:0003688 | DNA replication origin binding(GO:0003688) |
| 0.2 | 13.5 | GO:0003777 | microtubule motor activity(GO:0003777) |
| 0.1 | 13.0 | GO:0004386 | helicase activity(GO:0004386) |
| 0.5 | 12.8 | GO:0030515 | snoRNA binding(GO:0030515) |
| 0.4 | 11.0 | GO:0004003 | ATP-dependent DNA helicase activity(GO:0004003) |
| 0.8 | 10.5 | GO:0008097 | 5S rRNA binding(GO:0008097) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.5 | 26.7 | PID AURORA B PATHWAY | Aurora B signaling |
| 0.5 | 22.3 | PID ATR PATHWAY | ATR signaling pathway |
| 0.2 | 22.3 | PID MYC ACTIV PATHWAY | Validated targets of C-MYC transcriptional activation |
| 0.4 | 15.2 | PID AURORA A PATHWAY | Aurora A signaling |
| 0.4 | 12.7 | PID FANCONI PATHWAY | Fanconi anemia pathway |
| 0.3 | 12.7 | PID PLK1 PATHWAY | PLK1 signaling events |
| 0.3 | 10.2 | PID FOXM1 PATHWAY | FOXM1 transcription factor network |
| 0.1 | 8.5 | PID CDC42 PATHWAY | CDC42 signaling events |
| 0.1 | 6.9 | PID E2F PATHWAY | E2F transcription factor network |
| 0.1 | 6.8 | PID P53 REGULATION PATHWAY | p53 pathway |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.6 | 44.6 | REACTOME PEPTIDE CHAIN ELONGATION | Genes involved in Peptide chain elongation |
| 0.7 | 37.2 | REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX | Genes involved in Formation of the ternary complex, and subsequently, the 43S complex |
| 0.3 | 32.0 | REACTOME MITOTIC PROMETAPHASE | Genes involved in Mitotic Prometaphase |
| 0.6 | 20.2 | REACTOME INTERACTIONS OF VPR WITH HOST CELLULAR PROTEINS | Genes involved in Interactions of Vpr with host cellular proteins |
| 0.8 | 19.5 | REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX | Genes involved in Activation of the pre-replicative complex |
| 1.2 | 18.7 | REACTOME UNWINDING OF DNA | Genes involved in Unwinding of DNA |
| 0.7 | 17.8 | REACTOME KINESINS | Genes involved in Kinesins |
| 0.2 | 16.1 | REACTOME RESPIRATORY ELECTRON TRANSPORT | Genes involved in Respiratory electron transport |
| 0.2 | 12.8 | REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 | Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 |
| 0.5 | 11.6 | REACTOME FANCONI ANEMIA PATHWAY | Genes involved in Fanconi Anemia pathway |