ISMARA results: GGAAUGU

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avrg: 2D miR_HR1_12

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Results for GGAAUGU

Z-value: 1.15

Motif logo

miRNA associated with seed GGAAUGU

Name	miRBASE accession
mmu-miR-1a-3p miRBase	MIMAT0000123
mmu-miR-206-3p miRBase	MIMAT0000239
mmu-miR-1957b miRBase	MIMAT0025145
mmu-miR-6349 miRBase	MIMAT0025092
mmu-miR-6382 miRBase	MIMAT0025128

Activity profile of GGAAUGU motif

Sorted Z-values of GGAAUGU motif

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Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr12_-_17176888 Show fit	1.30	ENSMUST00000170580.1	Kcnf1 Ensembl NCBI MGI UniProt Show fit	potassium voltage-gated channel, subfamily F, member 1
chr8_+_35375719 Show fit	0.94	ENSMUST00000070481.6	Ppp1r3b Ensembl NCBI MGI UniProt Show fit	protein phosphatase 1, regulatory (inhibitor) subunit 3B
chr9_-_96889381 Show fit	0.89	ENSMUST00000112951.2 ENSMUST00000126411.1 ENSMUST00000078478.1 ENSMUST00000119141.1 ENSMUST00000120101.1	Acpl2 Ensembl NCBI MGI UniProt Show fit	acid phosphatase-like 2
chr8_+_82863351 Show fit	0.84	ENSMUST00000078525.5	Rnf150 Ensembl NCBI MGI UniProt Show fit	ring finger protein 150
chr5_-_65492984 Show fit	0.81	ENSMUST00000139122.1	Smim14 Ensembl NCBI MGI UniProt Show fit	small integral membrane protein 14
chr8_+_23411490 Show fit	0.72	ENSMUST00000033952.7	Sfrp1 Ensembl NCBI MGI UniProt Show fit	secreted frizzled-related protein 1
chr9_-_56928350 Show fit	0.63	ENSMUST00000050916.5	Snx33 Ensembl NCBI MGI UniProt Show fit	sorting nexin 33
chr5_-_107289561 Show fit	0.59	ENSMUST00000031224.8	Tgfbr3 Ensembl NCBI MGI UniProt Show fit	transforming growth factor, beta receptor III
chr3_-_84304762 Show fit	0.59	ENSMUST00000107692.1	Trim2 Ensembl NCBI MGI UniProt Show fit	tripartite motif-containing 2
chr8_+_57320975 Show fit	0.59	ENSMUST00000040104.3	Hand2 Ensembl NCBI MGI UniProt Show fit	heart and neural crest derivatives expressed transcript 2

Showing 1 to 10 of 200 entries

Network of associatons between targets according to the STRING database.

First level regulatory network of GGAAUGU

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.9	GO:0005981	regulation of glycogen catabolic process(GO:0005981)
0.0	0.9	GO:1901841	regulation of high voltage-gated calcium channel activity(GO:1901841)
0.0	0.9	GO:0048266	behavioral response to pain(GO:0048266)
0.1	0.8	GO:0033148	positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.2	0.7	GO:2000041	Wnt signaling pathway involved in somitogenesis(GO:0090244) regulation of planar cell polarity pathway involved in axis elongation(GO:2000040) negative regulation of planar cell polarity pathway involved in axis elongation(GO:2000041)
0.2	0.6	GO:0007181	transforming growth factor beta receptor complex assembly(GO:0007181)
0.1	0.6	GO:0003219	cardiac right ventricle formation(GO:0003219)
0.1	0.6	GO:0044351	cleavage furrow formation(GO:0036089) macropinocytosis(GO:0044351)
0.0	0.6	GO:0048280	vesicle fusion with Golgi apparatus(GO:0048280)
0.0	0.6	GO:0006614	SRP-dependent cotranslational protein targeting to membrane(GO:0006614)

Showing 1 to 10 of 102 entries

Gene overrepresentation in cellular component category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	1.5	GO:0008076	voltage-gated potassium channel complex(GO:0008076)
0.0	1.1	GO:0030864	cortical actin cytoskeleton(GO:0030864)
0.1	0.9	GO:0042587	glycogen granule(GO:0042587)
0.0	0.7	GO:0030285	integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.2	0.6	GO:0034673	inhibin-betaglycan-ActRII complex(GO:0034673)
0.2	0.6	GO:0070033	synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
0.0	0.6	GO:0031201	SNARE complex(GO:0031201)
0.2	0.5	GO:0098830	presynaptic endosome(GO:0098830)
0.0	0.5	GO:0035102	PRC1 complex(GO:0035102)
0.0	0.5	GO:0000930	gamma-tubulin complex(GO:0000930)

Showing 1 to 10 of 41 entries

Gene overrepresentation in molecular function category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	1.4	GO:0019888	protein phosphatase regulator activity(GO:0019888)
0.0	1.4	GO:0005249	voltage-gated potassium channel activity(GO:0005249)
0.1	0.8	GO:0008349	MAP kinase kinase kinase kinase activity(GO:0008349)
0.0	0.8	GO:0004197	cysteine-type endopeptidase activity(GO:0004197)
0.0	0.7	GO:0035925	mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0	0.7	GO:0017075	syntaxin-1 binding(GO:0017075)
0.1	0.6	GO:0005114	type II transforming growth factor beta receptor binding(GO:0005114)
0.0	0.6	GO:0003680	AT DNA binding(GO:0003680)
0.2	0.5	GO:0030226	apolipoprotein receptor activity(GO:0030226) apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.1	0.5	GO:0030348	syntaxin-3 binding(GO:0030348)

Showing 1 to 10 of 62 entries

Gene overrepresentation in curated gene sets: canonical pathways category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.9	PID RXR VDR PATHWAY	RXR and RAR heterodimerization with other nuclear receptor
0.0	0.8	ST WNT BETA CATENIN PATHWAY	Wnt/beta-catenin Pathway
0.0	0.8	PID TNF PATHWAY	TNF receptor signaling pathway
0.0	0.6	PID EPHRINB REV PATHWAY	Ephrin B reverse signaling
0.0	0.5	PID P38 MKK3 6PATHWAY	p38 MAPK signaling pathway
0.0	0.5	SIG CD40PATHWAYMAP	Genes related to CD40 signaling
0.0	0.4	PID RANBP2 PATHWAY	Sumoylation by RanBP2 regulates transcriptional repression
0.0	0.4	PID CERAMIDE PATHWAY	Ceramide signaling pathway
0.1	0.3	PID WNT NONCANONICAL PATHWAY	Noncanonical Wnt signaling pathway
0.0	0.3	PID WNT CANONICAL PATHWAY	Canonical Wnt signaling pathway

Showing 1 to 10 of 13 entries

Gene overrepresentation in curated gene sets: REACTOME pathways category:

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Log-likelihood per target	Total log-likelihood	Term	Description
0.0	1.5	REACTOME VOLTAGE GATED POTASSIUM CHANNELS	Genes involved in Voltage gated Potassium channels
0.1	1.0	REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE	Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0	0.5	REACTOME HDL MEDIATED LIPID TRANSPORT	Genes involved in HDL-mediated lipid transport
0.0	0.5	REACTOME DARPP 32 EVENTS	Genes involved in DARPP-32 events
0.0	0.4	REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE	Genes involved in Synthesis of PIPs at the Golgi membrane
0.0	0.4	REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING	Genes involved in Downregulation of TGF-beta receptor signaling
0.0	0.3	REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION	Genes involved in GABA synthesis, release, reuptake and degradation
0.0	0.3	REACTOME CTNNB1 PHOSPHORYLATION CASCADE	Genes involved in Beta-catenin phosphorylation cascade
0.0	0.3	REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS	Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0	0.2	REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES	Genes involved in Cytosolic sulfonation of small molecules

Showing 1 to 10 of 15 entries

Results for GGAAUGU

Z-value: 1.15

Motif logo

miRNA associated with seed GGAAUGU

Activity profile of GGAAUGU motif

Sorted Z-values of GGAAUGU motif

Top targets:

Network of associatons between targets according to the STRING database.

First level regulatory network of GGAAUGU

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Gene overrepresentation in cellular component category:

Gene overrepresentation in molecular function category:

Gene overrepresentation in curated gene sets: canonical pathways category:

Gene overrepresentation in curated gene sets: REACTOME pathways category: