Project
avrg: 2D miR_HR1_12
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Results for Myf6
Z-value: 4.04
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Transcription factors associated with Myf6
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr12_-_119238794 Show fit | 4.62 |
ENSMUST00000026360.8
|
integrin beta 8 |
|
| chr5_+_30588078 Show fit | 4.61 |
ENSMUST00000066295.2
|
potassium channel, subfamily K, member 3 |
|
| chr9_+_13621646 Show fit | 4.46 |
ENSMUST00000034401.8
|
mastermind like 2 (Drosophila) |
|
| chr17_-_87282771 Show fit | 4.45 |
ENSMUST00000161759.1
|
RIKEN cDNA 4833418N02 gene |
|
| chr6_+_107529717 Show fit | 4.21 |
ENSMUST00000049285.8
|
leucine rich repeat protein 1, neuronal |
|
| chrX_-_108664891 Show fit | 4.14 |
ENSMUST00000178160.1
|
predicted gene 379 |
|
| chr2_+_130295148 Show fit | 3.51 |
ENSMUST00000110288.2
|
early B cell factor 4 |
|
| chr6_-_112489808 Show fit | 3.50 |
ENSMUST00000053306.6
|
oxytocin receptor |
|
| chr17_-_87282793 Show fit | 3.48 |
ENSMUST00000146560.2
|
RIKEN cDNA 4833418N02 gene |
|
| chr14_+_59625281 Show fit | 3.41 |
ENSMUST00000053949.5
|
shisa homolog 2 (Xenopus laevis) |
Network of associatons between targets according to the STRING database.
First level regulatory network of Myf6
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 7.4 | GO:0001573 | ganglioside metabolic process(GO:0001573) |
| 0.5 | 6.8 | GO:0060363 | cranial suture morphogenesis(GO:0060363) |
| 0.1 | 5.5 | GO:0009409 | response to cold(GO:0009409) |
| 0.5 | 5.2 | GO:0007221 | positive regulation of transcription of Notch receptor target(GO:0007221) |
| 1.0 | 4.8 | GO:0006987 | activation of signaling protein activity involved in unfolded protein response(GO:0006987) |
| 0.4 | 3.9 | GO:1900034 | regulation of cellular response to heat(GO:1900034) |
| 0.4 | 3.6 | GO:0015074 | DNA integration(GO:0015074) |
| 0.3 | 3.6 | GO:0030322 | stabilization of membrane potential(GO:0030322) |
| 0.9 | 3.5 | GO:0001992 | regulation of systemic arterial blood pressure by vasopressin(GO:0001992) |
| 0.3 | 3.4 | GO:0019800 | peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 7.1 | GO:0005578 | proteinaceous extracellular matrix(GO:0005578) |
| 0.8 | 6.8 | GO:0032937 | SREBP-SCAP-Insig complex(GO:0032937) |
| 0.1 | 5.5 | GO:0008305 | integrin complex(GO:0008305) |
| 0.0 | 5.2 | GO:0005902 | microvillus(GO:0005902) |
| 0.4 | 3.9 | GO:0045298 | tubulin complex(GO:0045298) |
| 0.6 | 3.7 | GO:1990604 | IRE1-TRAF2-ASK1 complex(GO:1990604) |
| 0.3 | 3.5 | GO:0042612 | MHC class I protein complex(GO:0042612) |
| 0.1 | 3.3 | GO:0016327 | apicolateral plasma membrane(GO:0016327) |
| 0.2 | 3.2 | GO:0005892 | acetylcholine-gated channel complex(GO:0005892) |
| 0.1 | 3.2 | GO:0005891 | voltage-gated calcium channel complex(GO:0005891) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.9 | 6.1 | GO:1990430 | extracellular matrix protein binding(GO:1990430) |
| 0.3 | 5.7 | GO:0005161 | platelet-derived growth factor receptor binding(GO:0005161) |
| 0.2 | 4.8 | GO:0047617 | acyl-CoA hydrolase activity(GO:0047617) |
| 0.3 | 4.7 | GO:0022840 | leak channel activity(GO:0022840) narrow pore channel activity(GO:0022842) |
| 0.0 | 4.3 | GO:0019905 | syntaxin binding(GO:0019905) |
| 0.3 | 4.1 | GO:0030881 | beta-2-microglobulin binding(GO:0030881) |
| 0.0 | 4.1 | GO:0003713 | transcription coactivator activity(GO:0003713) |
| 0.6 | 3.9 | GO:0099609 | microtubule lateral binding(GO:0099609) |
| 0.2 | 3.8 | GO:0051787 | misfolded protein binding(GO:0051787) |
| 0.0 | 3.6 | GO:0004222 | metalloendopeptidase activity(GO:0004222) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 7.0 | PID HES HEY PATHWAY | Notch-mediated HES/HEY network |
| 0.3 | 5.9 | PID INTEGRIN5 PATHWAY | Beta5 beta6 beta7 and beta8 integrin cell surface interactions |
| 0.0 | 4.6 | NABA ECM REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
| 0.0 | 3.9 | PID P75 NTR PATHWAY | p75(NTR)-mediated signaling |
| 0.2 | 3.7 | PID P38 GAMMA DELTA PATHWAY | Signaling mediated by p38-gamma and p38-delta |
| 0.1 | 3.6 | NABA PROTEOGLYCANS | Genes encoding proteoglycans |
| 0.1 | 3.0 | PID ERBB1 INTERNALIZATION PATHWAY | Internalization of ErbB1 |
| 0.1 | 2.2 | PID UPA UPAR PATHWAY | Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling |
| 0.0 | 2.2 | PID MYC REPRESS PATHWAY | Validated targets of C-MYC transcriptional repression |
| 0.1 | 2.1 | PID IL5 PATHWAY | IL5-mediated signaling events |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 11.3 | REACTOME PEPTIDE LIGAND BINDING RECEPTORS | Genes involved in Peptide ligand-binding receptors |
| 0.3 | 5.4 | REACTOME NOTCH HLH TRANSCRIPTION PATHWAY | Genes involved in Notch-HLH transcription pathway |
| 0.2 | 5.0 | REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS | Genes involved in Caspase-mediated cleavage of cytoskeletal proteins |
| 0.1 | 4.7 | REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS | Genes involved in Association of TriC/CCT with target proteins during biosynthesis |
| 0.1 | 4.7 | REACTOME INTEGRIN CELL SURFACE INTERACTIONS | Genes involved in Integrin cell surface interactions |
| 0.1 | 4.1 | REACTOME UNFOLDED PROTEIN RESPONSE | Genes involved in Unfolded Protein Response |
| 0.0 | 4.1 | REACTOME SIGNALING BY RHO GTPASES | Genes involved in Signaling by Rho GTPases |
| 0.0 | 3.9 | REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 | Genes involved in Response to elevated platelet cytosolic Ca2+ |
| 0.1 | 3.7 | REACTOME COLLAGEN FORMATION | Genes involved in Collagen formation |
| 0.4 | 3.6 | REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS | Genes involved in Tandem pore domain potassium channels |