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2D miR_HR1_12

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Results for Foxl1

Z-value: 0.37

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Transcription factors associated with Foxl1

Gene Symbol Gene ID Gene Info
ENSMUSG00000097084.1 forkhead box L1
ENSMUSG00000043867.5 forkhead box L1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Foxl1mm10_v2_chr8_+_121127827_121127940-0.451.4e-01Click!

Activity profile of Foxl1 motif

Sorted Z-values of Foxl1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr4_-_99654983 0.62 ENSMUST00000136525.1
predicted gene 12688
chr2_-_94264713 0.58 ENSMUST00000129661.1
RIKEN cDNA E530001K10 gene
chr13_-_23622502 0.44 ENSMUST00000062045.2
histone cluster 1, H1e
chr16_-_22439570 0.42 ENSMUST00000170393.1
ets variant gene 5
chr2_-_94264745 0.37 ENSMUST00000134563.1
RIKEN cDNA E530001K10 gene
chr5_+_102481374 0.32 ENSMUST00000094559.2
ENSMUST00000073302.5
Rho GTPase activating protein 24
chr12_+_69963452 0.31 ENSMUST00000110560.1
predicted gene 3086
chr5_+_102481546 0.28 ENSMUST00000112854.1
Rho GTPase activating protein 24
chr16_+_30065333 0.27 ENSMUST00000023171.7
hairy and enhancer of split 1 (Drosophila)
chr13_+_23555023 0.25 ENSMUST00000045301.6
histone cluster 1, H1d
chr13_+_23575753 0.24 ENSMUST00000105105.1
histone cluster 1, H3d
chr17_-_91092715 0.22 ENSMUST00000160800.2
ENSMUST00000159778.1
ENSMUST00000160844.3
neurexin I
chr15_-_11905609 0.17 ENSMUST00000066529.3
natriuretic peptide receptor 3
chr3_-_83049797 0.17 ENSMUST00000048246.3
fibrinogen beta chain
chr2_+_86046451 0.17 ENSMUST00000079298.2
olfactory receptor 1034
chr13_+_23738804 0.16 ENSMUST00000040914.1
histone cluster 1, H1c
chr9_-_101198999 0.16 ENSMUST00000066773.7
protein phosphatase 2, regulatory subunit B'', alpha
chr2_+_91256144 0.13 ENSMUST00000154959.1
ENSMUST00000059566.4
protein kinase C and casein kinase substrate in neurons 3
chr3_+_129836729 0.13 ENSMUST00000077918.5
complement component factor i
chr7_+_91090728 0.11 ENSMUST00000074273.3
discs, large homolog 2 (Drosophila)
chr7_+_91090697 0.10 ENSMUST00000107196.2
discs, large homolog 2 (Drosophila)
chr7_+_122289297 0.10 ENSMUST00000064989.5
ENSMUST00000064921.4
protein kinase C, beta
chr11_+_31872100 0.09 ENSMUST00000020543.6
ENSMUST00000109412.2
cytoplasmic polyadenylation element binding protein 4
chr18_+_34409415 0.08 ENSMUST00000166156.1
ENSMUST00000014647.7
polycystic kidney disease 2-like 2
chr9_+_71215779 0.07 ENSMUST00000034723.5
aldehyde dehydrogenase family 1, subfamily A2
chr4_-_134853294 0.07 ENSMUST00000030628.8
transmembrane protein 57
chr15_-_101869695 0.07 ENSMUST00000087996.5
keratin 77
chr9_+_121777607 0.05 ENSMUST00000098272.2
kelch-like 40
chr5_+_33018816 0.04 ENSMUST00000019109.7
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta polypeptide
chrX_+_18162575 0.04 ENSMUST00000044484.6
ENSMUST00000052368.8
lysine (K)-specific demethylase 6A
chr4_-_121017201 0.04 ENSMUST00000043200.7
small ArfGAP 2
chr2_+_86041317 0.04 ENSMUST00000111589.1
olfactory receptor 1033
chr18_-_15151427 0.03 ENSMUST00000025992.6
potassium channel tetramerisation domain containing 1
chr18_-_25753852 0.03 ENSMUST00000025117.6
ENSMUST00000115816.2
CUGBP, Elav-like family member 4
chr2_+_18055203 0.03 ENSMUST00000028076.8
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10
chr15_+_43477213 0.03 ENSMUST00000022962.6
ER membrane protein complex subunit 2
chr7_-_119479249 0.01 ENSMUST00000033263.4
uromodulin
chr2_+_91255954 0.01 ENSMUST00000134699.1
protein kinase C and casein kinase substrate in neurons 3
chrX_+_112604274 0.01 ENSMUST00000071814.6
zinc finger protein 711
chr6_-_134887783 0.00 ENSMUST00000066107.6
G protein-coupled receptor 19
chr2_-_147186389 0.00 ENSMUST00000109970.3
ENSMUST00000067075.5
NK2 homeobox 2
chr2_+_119325784 0.00 ENSMUST00000102517.3
delta-like 4 (Drosophila)

Network of associatons between targets according to the STRING database.

First level regulatory network of Foxl1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 GO:0016584 nucleosome positioning(GO:0016584)
0.1 0.3 GO:2000978 trochlear nerve development(GO:0021558) negative regulation of forebrain neuron differentiation(GO:2000978)
0.1 0.4 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.1 0.6 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.1 0.2 GO:0090126 protein complex assembly involved in synapse maturation(GO:0090126)
0.0 0.2 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.0 0.2 GO:0007525 somatic muscle development(GO:0007525)
0.0 0.1 GO:0035799 ureter maturation(GO:0035799)
0.0 0.1 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.0 0.2 GO:0002158 osteoclast proliferation(GO:0002158)
0.0 0.0 GO:0006713 glucocorticoid catabolic process(GO:0006713)
0.0 0.2 GO:0045161 neuronal ion channel clustering(GO:0045161)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.7 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.2 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.2 GO:0044224 juxtaparanode region of axon(GO:0044224)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0071820 N-box binding(GO:0071820)
0.0 0.4 GO:0032564 dATP binding(GO:0032564)
0.0 0.2 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 0.2 GO:0097109 neuroligin family protein binding(GO:0097109)
0.0 0.1 GO:0035184 histone threonine kinase activity(GO:0035184)
0.0 0.2 GO:0005549 odorant binding(GO:0005549)
0.0 0.2 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.1 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 0.1 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.4 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.2 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.1 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade