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2D miR_HR1_12

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Results for Foxa3

Z-value: 1.41

Motif logo

Transcription factors associated with Foxa3

Gene Symbol Gene ID Gene Info
ENSMUSG00000040891.5 forkhead box A3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Foxa3mm10_v2_chr7_-_19023538_190235460.652.3e-02Click!

Activity profile of Foxa3 motif

Sorted Z-values of Foxa3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chrX_-_108664891 6.82 ENSMUST00000178160.1
predicted gene 379
chr4_+_104766334 6.19 ENSMUST00000065072.6
complement component 8, beta polypeptide
chr4_+_104766308 5.30 ENSMUST00000031663.3
complement component 8, beta polypeptide
chr3_+_138277489 4.32 ENSMUST00000004232.9
alcohol dehydrogenase 1 (class I)
chr9_+_46228580 3.43 ENSMUST00000034588.8
apolipoprotein A-I
chr11_-_99986593 2.57 ENSMUST00000105050.2
keratin associated protein 16-1
chr3_-_113258837 2.27 ENSMUST00000098673.3
amylase 2a5
chr7_+_131032061 2.24 ENSMUST00000084509.3
deleted in malignant brain tumors 1
chr13_-_95478655 2.20 ENSMUST00000022186.3
S100 calcium binding protein, zeta
chr5_-_108795352 2.14 ENSMUST00000004943.1
transmembrane emp24 protein transport domain containing
chr8_+_105427634 1.95 ENSMUST00000067305.6
leucine rich repeat containing 36
chr17_-_31144271 1.93 ENSMUST00000024826.7
trefoil factor 2 (spasmolytic protein 1)
chr8_+_107119110 1.91 ENSMUST00000046116.1
RIKEN cDNA C630050I24 gene
chr2_-_62483637 1.88 ENSMUST00000136686.1
ENSMUST00000102733.3
glucagon
chr9_+_98490522 1.81 ENSMUST00000035029.2
retinol binding protein 2, cellular
chr6_+_97991776 1.72 ENSMUST00000043628.6
microphthalmia-associated transcription factor
chr10_+_127898515 1.68 ENSMUST00000047134.7
4short chain dehydrogenase/reductase family 9C, member 7
chr17_+_70522083 1.58 ENSMUST00000148486.1
ENSMUST00000133717.1
discs, large (Drosophila) homolog-associated protein 1
chr2_+_164403194 1.55 ENSMUST00000017151.1
recombination signal binding protein for immunoglobulin kappa J region-like
chr5_-_86906937 1.46 ENSMUST00000031181.9
ENSMUST00000113333.1
UDP glucuronosyltransferase 2 family, polypeptide B34
chr3_-_20275659 1.44 ENSMUST00000011607.5
carboxypeptidase B1 (tissue)
chrX_+_164140447 1.39 ENSMUST00000073973.4
angiotensin I converting enzyme (peptidyl-dipeptidase A) 2
chr16_-_88563166 1.29 ENSMUST00000049697.4
claudin 8
chr4_-_63154130 1.27 ENSMUST00000030041.4
alpha 1 microglobulin/bikunin
chr3_-_113532288 1.24 ENSMUST00000132353.1
amylase 2a1
chr3_-_145032765 1.22 ENSMUST00000029919.5
chloride channel calcium activated 3
chr11_-_100146120 1.22 ENSMUST00000007317.7
keratin 19
chr19_-_58454435 1.17 ENSMUST00000169850.1
glial cell line derived neurotrophic factor family receptor alpha 1
chr14_-_110755100 1.17 ENSMUST00000078386.2
SLIT and NTRK-like family, member 6
chr11_-_69197809 1.14 ENSMUST00000094078.3
ENSMUST00000021262.3
arachidonate 8-lipoxygenase
chr16_-_45492962 1.12 ENSMUST00000114585.2
predicted gene 609
chr16_+_17331371 1.09 ENSMUST00000023450.6
ENSMUST00000161034.1
serine (or cysteine) peptidase inhibitor, clade D, member 1
chr19_-_20727533 1.07 ENSMUST00000025656.3
aldehyde dehydrogenase family 1, subfamily A7
chr5_-_103211251 1.03 ENSMUST00000060871.5
ENSMUST00000112846.1
ENSMUST00000170792.1
ENSMUST00000112847.2
mitogen-activated protein kinase 10
chrX_+_140907602 1.03 ENSMUST00000033806.4
V-set and immunoglobulin domain containing 1
chr9_+_109931458 1.02 ENSMUST00000072772.5
ENSMUST00000035055.8
microtubule-associated protein 4
chr14_-_30943275 1.02 ENSMUST00000006704.8
ENSMUST00000163118.1
inter-alpha trypsin inhibitor, heavy chain 1
chr3_+_3508024 1.00 ENSMUST00000108393.1
ENSMUST00000017832.8
hepatocyte nuclear factor 4, gamma
chr10_-_93311073 0.98 ENSMUST00000008542.5
ELK3, member of ETS oncogene family
chr10_-_93310963 0.97 ENSMUST00000151153.1
ELK3, member of ETS oncogene family
chr7_-_27181149 0.93 ENSMUST00000071986.6
ENSMUST00000121848.1
melanoma inhibitory activity
chr14_-_41185188 0.91 ENSMUST00000077136.3
surfactant associated protein D
chr17_+_70522149 0.86 ENSMUST00000140728.1
discs, large (Drosophila) homolog-associated protein 1
chr1_+_88166004 0.84 ENSMUST00000097659.4
UDP glucuronosyltransferase 1 family, polypeptide A5
chr4_-_57916283 0.83 ENSMUST00000063816.5
RIKEN cDNA D630039A03 gene
chr1_+_43445736 0.83 ENSMUST00000086421.5
ENSMUST00000114744.1
non-catalytic region of tyrosine kinase adaptor protein 2
chr10_-_81230773 0.82 ENSMUST00000047408.4
ataxia, cerebellar, Cayman type homolog (human)
chr12_+_8012359 0.81 ENSMUST00000171239.1
apolipoprotein B
chr18_+_37742088 0.81 ENSMUST00000003599.6
protocadherin gamma subfamily A, 9
chr5_+_102481374 0.79 ENSMUST00000094559.2
ENSMUST00000073302.5
Rho GTPase activating protein 24
chr2_+_58755177 0.79 ENSMUST00000102755.3
uridine phosphorylase 2
chr6_-_137571007 0.76 ENSMUST00000100841.2
epidermal growth factor receptor pathway substrate 8
chr6_+_5390387 0.76 ENSMUST00000183358.1
ankyrin repeat and SOCS box-containing 4
chr7_-_103813913 0.75 ENSMUST00000098192.3
hemoglobin, beta adult t chain
chr16_+_44394771 0.75 ENSMUST00000099742.2
WD repeat domain 52
chr19_+_20601958 0.74 ENSMUST00000087638.3
aldehyde dehydrogenase family 1, subfamily A1
chr12_+_119443410 0.73 ENSMUST00000048880.6
metastasis associated in colon cancer 1
chr2_-_163645125 0.73 ENSMUST00000017851.3
serine incorporator 3
chr4_-_58499398 0.73 ENSMUST00000107570.1
lysophosphatidic acid receptor 1
chr4_+_45965327 0.72 ENSMUST00000107777.2
tudor domain containing 7
chr3_+_96219858 0.70 ENSMUST00000073115.4
histone cluster 2, H2ab
chr5_+_102481546 0.68 ENSMUST00000112854.1
Rho GTPase activating protein 24
chr10_-_128744014 0.67 ENSMUST00000026414.7
diacylglycerol kinase, alpha
chr2_+_58754910 0.66 ENSMUST00000059102.6
uridine phosphorylase 2
chr13_-_13393592 0.66 ENSMUST00000021738.8
G protein-coupled receptor 137B
chr11_+_96286623 0.65 ENSMUST00000049352.7
homeobox B7
chr6_+_139621888 0.63 ENSMUST00000032353.8
phosphatidylinositol 3-kinase, C2 domain containing, gamma polypeptide
chr13_-_74807913 0.63 ENSMUST00000065629.4
calpastatin
chr11_-_76027726 0.62 ENSMUST00000021207.6
family with sequence similarity 101, member B
chr13_+_23738804 0.61 ENSMUST00000040914.1
histone cluster 1, H1c
chr4_-_25281752 0.59 ENSMUST00000038705.7
UFM1 specific ligase 1
chr12_+_59131473 0.57 ENSMUST00000177162.1
CTAGE family, member 5
chr5_-_5664196 0.55 ENSMUST00000061008.3
ENSMUST00000054865.6
RIKEN cDNA A330021E22 gene
chr10_+_97565436 0.55 ENSMUST00000038160.4
lumican
chr8_+_69300776 0.54 ENSMUST00000078257.6
RIKEN cDNA D130040H23 gene
chr9_-_101198999 0.54 ENSMUST00000066773.7
protein phosphatase 2, regulatory subunit B'', alpha
chr11_+_78465697 0.50 ENSMUST00000001126.3
solute carrier family 46, member 1
chr3_-_106406090 0.50 ENSMUST00000029510.7
cDNA sequence BC051070
chr7_-_103827922 0.48 ENSMUST00000023934.6
ENSMUST00000153218.1
hemoglobin, beta adult s chain
chr10_-_128180265 0.47 ENSMUST00000099139.1
RNA binding motif, single stranded interacting protein 2
chr13_+_40859768 0.46 ENSMUST00000110191.2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme
chr12_-_84450944 0.46 ENSMUST00000085192.5
aldehyde dehydrogenase family 6, subfamily A1
chr19_-_58455903 0.45 ENSMUST00000131877.1
glial cell line derived neurotrophic factor family receptor alpha 1
chr15_-_42676967 0.45 ENSMUST00000022921.5
angiopoietin 1
chr11_+_78499087 0.44 ENSMUST00000017488.4
vitronectin
chr7_-_4844665 0.43 ENSMUST00000066041.5
ENSMUST00000172377.1
shisa homolog 7 (Xenopus laevis)
chr6_+_34863130 0.43 ENSMUST00000074949.3
transmembrane protein 140
chr2_+_24345305 0.43 ENSMUST00000114482.1
interleukin 1 receptor antagonist
chr19_+_56461629 0.43 ENSMUST00000178590.1
ENSMUST00000039666.6
pleckstrin homology domain containing, family S member 1
chr9_+_53301571 0.43 ENSMUST00000051014.1
exophilin 5
chrX_+_139563316 0.42 ENSMUST00000113027.1
ring finger protein 128
chr10_+_96616998 0.42 ENSMUST00000038377.7
B cell translocation gene 1, anti-proliferative
chr15_-_101869695 0.41 ENSMUST00000087996.5
keratin 77
chr15_+_4727175 0.41 ENSMUST00000162585.1
complement component 6
chr4_-_55532453 0.41 ENSMUST00000132746.1
ENSMUST00000107619.2
Kruppel-like factor 4 (gut)
chr1_+_75142775 0.41 ENSMUST00000097694.4
family with sequence similarity 134, member A
chr8_+_11556061 0.41 ENSMUST00000054399.4
inhibitor of growth family, member 1
chr1_+_93373874 0.41 ENSMUST00000058682.4
anoctamin 7
chr4_+_150853919 0.41 ENSMUST00000073600.2
ERBB receptor feedback inhibitor 1
chr16_+_33518278 0.40 ENSMUST00000122427.1
ENSMUST00000059056.8
solute carrier family 12 (potassium/chloride transporters), member 8
chr7_+_30565410 0.40 ENSMUST00000043850.7
IGF-like family receptor 1
chr8_+_106603351 0.40 ENSMUST00000000312.5
ENSMUST00000167688.1
cadherin 1
chr13_-_78196373 0.40 ENSMUST00000125176.2
nuclear receptor subfamily 2, group F, member 1
chr6_-_139501907 0.40 ENSMUST00000170650.1
RERG/RAS-like
chr12_+_84451485 0.38 ENSMUST00000137170.1
lin-52 homolog (C. elegans)
chr5_+_90561102 0.38 ENSMUST00000094615.4
RIKEN cDNA 5830473C10 gene
chr10_-_57532489 0.37 ENSMUST00000020027.4
serine incorporator 1
chr4_+_101717404 0.37 ENSMUST00000102777.3
ENSMUST00000106921.2
ENSMUST00000037552.3
ENSMUST00000145024.1
leptin receptor
chr18_-_38918642 0.36 ENSMUST00000040647.4
fibroblast growth factor 1
chr6_-_40951826 0.35 ENSMUST00000073642.5
predicted gene 4744
chr11_-_69662625 0.35 ENSMUST00000018905.5
mannose-P-dolichol utilization defect 1
chr19_-_37207293 0.34 ENSMUST00000132580.1
ENSMUST00000079754.4
ENSMUST00000136286.1
ENSMUST00000126188.1
ENSMUST00000126781.1
cytoplasmic polyadenylation element binding protein 3
chr16_+_33518528 0.34 ENSMUST00000119173.1
solute carrier family 12 (potassium/chloride transporters), member 8
chr15_-_5108469 0.34 ENSMUST00000141020.1
caspase recruitment domain family, member 6
chr1_-_132367879 0.34 ENSMUST00000142609.1
transmembrane and coiled-coil domains 2
chr3_+_121531603 0.33 ENSMUST00000180804.1
RIKEN cDNA A530020G20 gene
chr13_+_94173992 0.33 ENSMUST00000121618.1
lipoma HMGIC fusion partner-like 2
chrX_-_141725181 0.33 ENSMUST00000067841.7
insulin receptor substrate 4
chr2_-_77519565 0.33 ENSMUST00000111830.2
zinc finger protein 385B
chr12_-_87200200 0.32 ENSMUST00000037418.5
transmembrane emp24 domain containing 8
chr4_-_103026709 0.32 ENSMUST00000084382.5
ENSMUST00000106869.2
insulin-like 5
chr18_+_36952621 0.32 ENSMUST00000115661.2
protocadherin alpha 2
chr3_-_106167564 0.32 ENSMUST00000063062.8
chitinase 3-like 3
chr2_-_84425258 0.32 ENSMUST00000074262.2
calcitonin receptor-like
chr8_-_47713920 0.31 ENSMUST00000038738.5
CDKN2A interacting protein
chr3_+_134236483 0.30 ENSMUST00000181904.1
ENSMUST00000053048.9
CXXC finger 4
chr1_-_168431695 0.30 ENSMUST00000176790.1
pre B cell leukemia homeobox 1
chr12_+_55089202 0.29 ENSMUST00000021407.10
signal recognition particle 54A
chr1_-_45503282 0.29 ENSMUST00000086430.4
collagen, type V, alpha 2
chr12_+_87200524 0.29 ENSMUST00000182869.1
sterile alpha motif domain containing 15
chr7_-_84679346 0.29 ENSMUST00000069537.2
ENSMUST00000178385.1
zinc finger, AN1-type domain 6
chr1_-_156034826 0.29 ENSMUST00000141878.1
ENSMUST00000123705.1
torsin A interacting protein 1
chr7_+_113765998 0.29 ENSMUST00000046687.9
spondin 1, (f-spondin) extracellular matrix protein
chr12_+_7977640 0.27 ENSMUST00000171271.1
ENSMUST00000037811.6
ENSMUST00000037520.7
apolipoprotein B
chr2_+_91730127 0.27 ENSMUST00000099712.3
ENSMUST00000111317.2
ENSMUST00000111316.2
ENSMUST00000045705.7
autophagy/beclin 1 regulator 1
chr13_+_5861489 0.27 ENSMUST00000000080.6
Kruppel-like factor 6
chr2_-_126499839 0.26 ENSMUST00000040128.5
ATPase, class I, type 8B, member 4
chr1_+_17145357 0.26 ENSMUST00000026879.7
ganglioside-induced differentiation-associated-protein 1
chr4_-_36056726 0.26 ENSMUST00000108124.3
leucine rich repeat and Ig domain containing 2
chr15_-_95830072 0.26 ENSMUST00000168960.1
predicted gene, 17546
chr10_+_21992216 0.26 ENSMUST00000150089.1
ENSMUST00000100036.3
serum/glucocorticoid regulated kinase 1
chr14_+_46832127 0.25 ENSMUST00000068532.8
cell growth regulator with ring finger domain 1
chr12_-_31950535 0.25 ENSMUST00000172314.2
high mobility group box transcription factor 1
chr2_-_90479165 0.24 ENSMUST00000111495.2
protein tyrosine phosphatase, receptor type, J
chr11_-_99438143 0.24 ENSMUST00000017743.2
keratin 20
chr5_+_88583527 0.24 ENSMUST00000031229.6
RUN and FYVE domain containing 3
chr1_+_110099295 0.24 ENSMUST00000134301.1
cadherin 7, type 2
chr17_-_12675833 0.24 ENSMUST00000024596.8
solute carrier family 22 (organic cation transporter), member 1
chr2_+_143915273 0.24 ENSMUST00000103172.3
destrin
chr11_-_42000834 0.23 ENSMUST00000070725.4
gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2
chr1_+_51289106 0.23 ENSMUST00000051572.6
serum deprivation response
chr16_-_38433145 0.23 ENSMUST00000002926.6
phospholipase A1 member A
chr16_+_36156801 0.23 ENSMUST00000079184.4
stefin A2 like 1
chr3_+_106113229 0.22 ENSMUST00000079132.5
ENSMUST00000139086.1
chitinase, acidic
chr2_+_164833781 0.21 ENSMUST00000143780.1
cathepsin A
chr15_-_5108492 0.20 ENSMUST00000118365.2
caspase recruitment domain family, member 6
chr11_-_42000532 0.19 ENSMUST00000070735.3
gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2
chr16_+_49699198 0.19 ENSMUST00000046777.4
ENSMUST00000142682.1
intraflagellar transport 57
chr4_+_139653538 0.18 ENSMUST00000030510.7
ENSMUST00000166773.1
taste receptor, type 1, member 2
chrX_-_75578188 0.18 ENSMUST00000033545.5
RAB39B, member RAS oncogene family
chr15_-_81104999 0.18 ENSMUST00000109579.2
MKL (megakaryoblastic leukemia)/myocardin-like 1
chr15_+_102459193 0.17 ENSMUST00000164957.1
ENSMUST00000171245.1
proline rich 13
chr10_-_52195244 0.15 ENSMUST00000020045.3
Ros1 proto-oncogene
chr4_+_42916647 0.15 ENSMUST00000132173.1
ENSMUST00000107975.1
expressed sequence N28178
chr4_+_94739276 0.14 ENSMUST00000073939.6
ENSMUST00000102798.1
endothelial-specific receptor tyrosine kinase
chr2_+_153161303 0.14 ENSMUST00000089027.2
transmembrane 9 superfamily protein member 4
chr7_-_34655500 0.14 ENSMUST00000032709.1
potassium channel tetramerisation domain containing 15
chr17_+_45433823 0.14 ENSMUST00000181149.1
RIKEN cDNA B230354K17 gene
chr3_+_138415484 0.14 ENSMUST00000161312.1
ENSMUST00000013458.8
alcohol dehydrogenase 4 (class II), pi polypeptide
chr9_+_32224457 0.14 ENSMUST00000183121.1
Rho GTPase activating protein 32
chr12_-_31950210 0.14 ENSMUST00000176084.1
ENSMUST00000176103.1
ENSMUST00000167458.2
high mobility group box transcription factor 1
chr18_+_67133713 0.13 ENSMUST00000076605.7
guanine nucleotide binding protein, alpha stimulating, olfactory type
chr4_-_116405986 0.13 ENSMUST00000123072.1
ENSMUST00000144281.1
microtubule associated serine/threonine kinase 2
chr2_-_126500631 0.13 ENSMUST00000129187.1
ATPase, class I, type 8B, member 4
chr11_-_54860564 0.13 ENSMUST00000144164.1
LYR motif containing 7
chr10_-_57532416 0.12 ENSMUST00000169122.1
serine incorporator 1
chr15_+_102459028 0.12 ENSMUST00000164938.1
ENSMUST00000023810.5
proline rich 13
chr3_+_33799791 0.12 ENSMUST00000099153.3
tetratricopeptide repeat domain 14
chr8_-_125492710 0.12 ENSMUST00000108775.1
signal-induced proliferation-associated 1 like 2
chr12_+_71016658 0.11 ENSMUST00000125125.1
AT rich interactive domain 4A (RBP1-like)
chr12_-_56536895 0.11 ENSMUST00000001536.8
NK2 homeobox 1
chr4_-_127354074 0.11 ENSMUST00000106090.1
ENSMUST00000060419.1
gap junction protein, beta 4
chr9_+_70678950 0.11 ENSMUST00000067880.6
a disintegrin and metallopeptidase domain 10
chr1_-_75142360 0.11 ENSMUST00000041213.5
cyclin Pas1/PHO80 domain containing 1
chr17_-_45433682 0.10 ENSMUST00000024727.8
cell division cycle 5-like (S. pombe)
chr17_+_47505073 0.10 ENSMUST00000183210.1
cyclin D3
chr16_-_29378667 0.10 ENSMUST00000143373.1
ENSMUST00000075806.4
ATPase type 13A5
chr11_-_69662564 0.09 ENSMUST00000129224.1
ENSMUST00000155200.1
mannose-P-dolichol utilization defect 1
chr2_+_173737492 0.09 ENSMUST00000067530.4
vesicle-associated membrane protein, associated protein B and C
chr19_+_26623419 0.09 ENSMUST00000176584.1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr2_+_164833841 0.09 ENSMUST00000152721.1
cathepsin A
chr17_+_47505211 0.09 ENSMUST00000182935.1
ENSMUST00000182506.1
cyclin D3
chr12_+_31265279 0.08 ENSMUST00000002979.8
ENSMUST00000170495.1
laminin B1
chr1_-_132390301 0.08 ENSMUST00000132435.1
transmembrane and coiled-coil domains 2
chr3_-_89764581 0.08 ENSMUST00000029562.3
cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal)
chr17_+_47505117 0.08 ENSMUST00000183044.1
ENSMUST00000037333.10
cyclin D3
chr2_+_69723071 0.08 ENSMUST00000040915.8
peptidyl-prolyl isomerase G (cyclophilin G)
chr7_-_65371210 0.07 ENSMUST00000102592.3
tight junction protein 1
chr17_+_47505149 0.07 ENSMUST00000183177.1
ENSMUST00000182848.1
cyclin D3
chr15_-_99820072 0.07 ENSMUST00000109024.2
LIM domain and actin binding 1

Network of associatons between targets according to the STRING database.

First level regulatory network of Foxa3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 4.5 GO:0006069 ethanol oxidation(GO:0006069)
0.9 11.5 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.8 3.9 GO:0002740 negative regulation of cytokine secretion involved in immune response(GO:0002740)
0.4 1.2 GO:0060005 vestibular reflex(GO:0060005)
0.3 1.4 GO:0015801 aromatic amino acid transport(GO:0015801) tryptophan transport(GO:0015827)
0.3 1.9 GO:0060455 negative regulation of gastric acid secretion(GO:0060455)
0.3 0.8 GO:0045763 negative regulation of cellular amino acid metabolic process(GO:0045763)
0.3 1.9 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.2 1.1 GO:0051121 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.2 0.9 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.2 1.7 GO:0006776 vitamin A metabolic process(GO:0006776)
0.2 1.0 GO:0051012 microtubule sliding(GO:0051012)
0.2 0.8 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.2 2.4 GO:0070842 aggresome assembly(GO:0070842)
0.2 0.7 GO:1904566 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.2 1.0 GO:0007258 JUN phosphorylation(GO:0007258)
0.2 1.5 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.2 0.5 GO:0006210 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.1 0.7 GO:0009597 detection of virus(GO:0009597)
0.1 0.6 GO:0036493 positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493) negative regulation of PERK-mediated unfolded protein response(GO:1903898)
0.1 0.4 GO:0045415 negative regulation of interleukin-8 biosynthetic process(GO:0045415)
0.1 0.5 GO:0007525 somatic muscle development(GO:0007525)
0.1 0.4 GO:0060066 oviduct development(GO:0060066)
0.1 1.7 GO:0044336 canonical Wnt signaling pathway involved in negative regulation of apoptotic process(GO:0044336)
0.1 0.4 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.1 1.8 GO:0042573 retinoic acid metabolic process(GO:0042573)
0.1 2.2 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.1 1.3 GO:0018298 protein-chromophore linkage(GO:0018298)
0.1 0.3 GO:0002182 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
0.1 0.5 GO:0032914 positive regulation of transforming growth factor beta1 production(GO:0032914)
0.1 1.1 GO:0006642 triglyceride mobilization(GO:0006642)
0.1 0.4 GO:1903243 negative regulation of tumor necrosis factor biosynthetic process(GO:0042536) negative regulation of cardiac muscle hypertrophy in response to stress(GO:1903243)
0.1 0.6 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.1 0.5 GO:1904222 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.1 0.4 GO:0061589 calcium activated phosphatidylserine scrambling(GO:0061589)
0.1 0.3 GO:0034285 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.1 0.5 GO:0036438 maintenance of lens transparency(GO:0036438)
0.1 0.6 GO:0016584 nucleosome positioning(GO:0016584)
0.1 0.3 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.1 0.5 GO:0051958 methotrexate transport(GO:0051958)
0.1 0.4 GO:1901509 regulation of endothelial tube morphogenesis(GO:1901509)
0.1 0.4 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.1 0.8 GO:0052696 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.1 0.8 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.1 1.0 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.1 0.6 GO:0007343 egg activation(GO:0007343)
0.1 0.2 GO:0010248 establishment or maintenance of transmembrane electrochemical gradient(GO:0010248)
0.1 0.4 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.1 0.2 GO:0030043 actin filament fragmentation(GO:0030043)
0.1 0.3 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.0 0.3 GO:1904715 negative regulation of chaperone-mediated autophagy(GO:1904715)
0.0 0.7 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654) diacylglycerol metabolic process(GO:0046339)
0.0 0.4 GO:0097421 liver regeneration(GO:0097421)
0.0 0.1 GO:0021759 globus pallidus development(GO:0021759)
0.0 1.4 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.0 0.2 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.0 0.1 GO:0048014 Tie signaling pathway(GO:0048014)
0.0 0.2 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.0 0.4 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.4 GO:0071420 cellular response to histamine(GO:0071420)
0.0 0.7 GO:0039694 viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)
0.0 0.3 GO:0071763 nuclear membrane organization(GO:0071763)
0.0 1.2 GO:0060706 cell differentiation involved in embryonic placenta development(GO:0060706)
0.0 0.1 GO:0060084 synaptic transmission involved in micturition(GO:0060084)
0.0 0.4 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.0 0.2 GO:0010966 regulation of phosphate transport(GO:0010966)
0.0 0.2 GO:0043116 negative regulation of vascular permeability(GO:0043116)
0.0 0.1 GO:0009405 pathogenesis(GO:0009405)
0.0 0.4 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.7 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 0.3 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 0.1 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
0.0 0.1 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.0 0.4 GO:0042036 negative regulation of cytokine biosynthetic process(GO:0042036)
0.0 0.3 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.0 0.1 GO:0042090 interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.0 0.3 GO:0098780 response to mitochondrial depolarisation(GO:0098780)
0.0 0.2 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.0 0.1 GO:0070072 vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 0.1 GO:0017062 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 0.3 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 0.3 GO:0010971 positive regulation of G2/M transition of mitotic cell cycle(GO:0010971)
0.0 0.4 GO:0032369 negative regulation of lipid transport(GO:0032369)
0.0 0.2 GO:0045109 intermediate filament organization(GO:0045109)
0.0 0.1 GO:0045925 positive regulation of female receptivity(GO:0045925) positive regulation of glucocorticoid receptor signaling pathway(GO:2000324)
0.0 0.3 GO:0006625 protein targeting to peroxisome(GO:0006625) peroxisomal transport(GO:0043574) protein localization to peroxisome(GO:0072662) establishment of protein localization to peroxisome(GO:0072663)
0.0 1.4 GO:0009166 nucleotide catabolic process(GO:0009166)
0.0 0.1 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 11.5 GO:0005579 membrane attack complex(GO:0005579)
0.7 3.4 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.4 2.2 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.3 1.2 GO:0005833 hemoglobin complex(GO:0005833)
0.2 1.4 GO:0045098 type III intermediate filament(GO:0045098)
0.2 1.1 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.2 1.2 GO:1990357 terminal web(GO:1990357)
0.1 3.0 GO:0045095 keratin filament(GO:0045095)
0.1 0.8 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.1 0.3 GO:0005588 collagen type V trimer(GO:0005588)
0.1 0.4 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.1 1.4 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 0.5 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.8 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.7 GO:0033391 chromatoid body(GO:0033391)
0.0 0.3 GO:0001652 granular component(GO:0001652)
0.0 0.4 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.0 0.3 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.0 0.4 GO:0043219 catenin complex(GO:0016342) flotillin complex(GO:0016600) lateral loop(GO:0043219)
0.0 0.6 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.5 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.9 GO:0005771 multivesicular body(GO:0005771)
0.0 0.4 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 0.6 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.3 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 0.2 GO:0071437 invadopodium(GO:0071437)
0.0 1.8 GO:0072562 blood microparticle(GO:0072562)
0.0 1.5 GO:0005930 axoneme(GO:0005930)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.5 4.5 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.9 3.4 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
0.6 1.8 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.5 1.9 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.3 2.3 GO:0004556 alpha-amylase activity(GO:0004556)
0.3 1.2 GO:0031720 haptoglobin binding(GO:0031720)
0.3 1.4 GO:0004850 uridine phosphorylase activity(GO:0004850)
0.3 1.0 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.2 1.4 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.2 0.6 GO:0071568 UFM1 transferase activity(GO:0071568)
0.2 1.9 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.2 1.8 GO:0019841 retinol binding(GO:0019841)
0.1 1.1 GO:0035473 lipase binding(GO:0035473)
0.1 0.5 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.1 0.3 GO:0004948 calcitonin receptor activity(GO:0004948)
0.1 0.7 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.1 0.7 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1 1.3 GO:0019865 immunoglobulin binding(GO:0019865)
0.1 1.4 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.1 1.2 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.1 0.4 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.1 0.2 GO:0005333 norepinephrine transmembrane transporter activity(GO:0005333)
0.1 0.5 GO:0015350 methotrexate transporter activity(GO:0015350)
0.1 2.3 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.1 0.3 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.1 0.3 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.1 1.4 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 1.1 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.7 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 2.4 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.6 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.9 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 0.2 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.0 0.3 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.0 1.7 GO:0070888 E-box binding(GO:0070888)
0.0 0.4 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.2 GO:0008527 taste receptor activity(GO:0008527)
0.0 0.4 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.6 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.4 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 0.1 GO:0071987 WD40-repeat domain binding(GO:0071987)
0.0 0.3 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 1.2 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.1 GO:0005151 interleukin-1, Type II receptor binding(GO:0005151) interleukin-1 receptor antagonist activity(GO:0005152) interleukin-1 Type I receptor antagonist activity(GO:0045352) interleukin-1 Type II receptor antagonist activity(GO:0045353)
0.0 0.4 GO:0044548 S100 protein binding(GO:0044548)
0.0 0.4 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.4 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.8 GO:0050699 WW domain binding(GO:0050699)
0.0 0.2 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.0 0.2 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.4 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 1.0 GO:0098531 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)
0.0 1.6 GO:0005178 integrin binding(GO:0005178)
0.0 0.3 GO:0005521 lamin binding(GO:0005521)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.3 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 3.4 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.1 3.5 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 1.0 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 2.2 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 1.4 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.8 PID REELIN PATHWAY Reelin signaling pathway
0.0 0.7 PID AURORA A PATHWAY Aurora A signaling
0.0 0.9 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 3.0 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.8 PID RAC1 REG PATHWAY Regulation of RAC1 activity

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 8.8 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.2 4.5 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.1 0.9 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.1 2.3 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.1 1.4 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.1 0.8 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.1 1.0 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.1 1.8 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0 0.4 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.6 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.6 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 1.9 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.1 REACTOME OLFACTORY SIGNALING PATHWAY Genes involved in Olfactory Signaling Pathway
0.0 1.3 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.5 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.4 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.0 0.4 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 1.0 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.2 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.5 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.7 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.3 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.6 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.5 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport