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2D miR_HR1_12

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Results for Gli2

Z-value: 0.99

Motif logo

Transcription factors associated with Gli2

Gene Symbol Gene ID Gene Info
ENSMUSG00000048402.8 GLI-Kruppel family member GLI2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Gli2mm10_v2_chr1_-_119053619_119053638-0.746.4e-03Click!

Activity profile of Gli2 motif

Sorted Z-values of Gli2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr5_-_100159261 1.91 ENSMUST00000139520.1
transmembrane protein 150C
chrX_-_7574120 1.71 ENSMUST00000045924.7
ENSMUST00000115742.2
ENSMUST00000150787.1
protein phosphatase 1, regulatory (inhibitor) subunit 3F
chr5_-_117319242 1.48 ENSMUST00000100834.1
predicted gene 10399
chr6_-_72789240 1.30 ENSMUST00000069536.5
transcription factor 7 like 1 (T cell specific, HMG box)
chr8_+_127064107 1.30 ENSMUST00000162536.1
ENSMUST00000026921.6
ENSMUST00000162665.1
ENSMUST00000160766.1
ENSMUST00000162602.1
ENSMUST00000162531.1
ENSMUST00000160581.1
ENSMUST00000161355.1
ENSMUST00000159537.1
par-3 (partitioning defective 3) homolog (C. elegans)
chr11_-_107794557 1.25 ENSMUST00000021066.3
calcium channel, voltage-dependent, gamma subunit 4
chr1_-_90967667 1.19 ENSMUST00000131428.1
RAB17, member RAS oncogene family
chr5_+_117319292 1.14 ENSMUST00000086464.4
V-set and immunoglobulin domain containing 10
chr6_-_72788952 1.11 ENSMUST00000114053.2
transcription factor 7 like 1 (T cell specific, HMG box)
chr5_+_117319258 1.10 ENSMUST00000111967.1
V-set and immunoglobulin domain containing 10
chr8_+_127063893 1.08 ENSMUST00000162309.1
par-3 (partitioning defective 3) homolog (C. elegans)
chr4_-_140648736 1.05 ENSMUST00000039204.3
ENSMUST00000105799.1
ENSMUST00000097820.2
Rho guanine nucleotide exchange factor (GEF) 10-like
chr9_+_114978507 1.02 ENSMUST00000183104.1
oxysterol binding protein-like 10
chr7_+_28540863 1.01 ENSMUST00000119180.2
syncollin
chr18_-_35215008 0.97 ENSMUST00000091636.3
leucine rich repeat transmembrane neuronal 2
chr12_-_70227622 0.96 ENSMUST00000071250.6
liver glycogen phosphorylase
chr9_+_100643605 0.96 ENSMUST00000041418.6
stromal antigen 1
chr3_+_97628804 0.95 ENSMUST00000107050.1
ENSMUST00000029729.8
ENSMUST00000107049.1
flavin containing monooxygenase 5
chr12_+_58211772 0.91 ENSMUST00000110671.2
ENSMUST00000044299.2
somatostatin receptor 1
chr11_+_96929260 0.88 ENSMUST00000054311.5
ENSMUST00000107636.3
proline rich 15-like
chr11_+_101176041 0.87 ENSMUST00000103109.3
contactin associated protein-like 1
chr8_+_76902277 0.84 ENSMUST00000109912.1
ENSMUST00000128862.1
ENSMUST00000109911.1
nuclear receptor subfamily 3, group C, member 2
chr16_-_31314804 0.83 ENSMUST00000115230.1
ENSMUST00000130560.1
apolipoprotein D
chr9_+_100643448 0.83 ENSMUST00000146312.1
ENSMUST00000129269.1
stromal antigen 1
chr8_+_127064022 0.83 ENSMUST00000160272.1
ENSMUST00000079777.5
ENSMUST00000162907.1
par-3 (partitioning defective 3) homolog (C. elegans)
chr11_+_96929367 0.78 ENSMUST00000062172.5
proline rich 15-like
chr11_+_62847111 0.77 ENSMUST00000150989.1
ENSMUST00000176577.1
F-box and WD-40 domain protein 10
chr4_+_63215402 0.74 ENSMUST00000036300.6
collagen, type XXVII, alpha 1
chr6_-_124464772 0.73 ENSMUST00000008297.4
calsyntenin 3
chr19_-_43674844 0.71 ENSMUST00000046038.7
solute carrier family 25, member 28
chr4_-_46536134 0.68 ENSMUST00000046897.6
tripartite motif-containing 14
chr4_+_32800246 0.67 ENSMUST00000062802.4
LYR motif containing 2
chr15_+_95790831 0.66 ENSMUST00000071874.6
anoctamin 6
chr8_+_85060055 0.66 ENSMUST00000095220.3
F-box and WD-40 domain protein 9
chr2_-_104712122 0.61 ENSMUST00000111118.1
ENSMUST00000028597.3
t-complex 11 like 1
chr11_+_116030304 0.60 ENSMUST00000021116.5
ENSMUST00000106452.1
unkempt homolog (Drosophila)
chr9_+_107576915 0.59 ENSMUST00000112387.2
ENSMUST00000123005.1
ENSMUST00000010195.7
ENSMUST00000144392.1
hyaluronoglucosaminidase 1
chr4_+_40472180 0.59 ENSMUST00000049655.2
transmembrane protein 215
chr7_-_137314394 0.58 ENSMUST00000168203.1
ENSMUST00000106118.2
ENSMUST00000169486.2
ENSMUST00000033378.5
early B cell factor 3
chr6_-_137649211 0.58 ENSMUST00000134630.1
ENSMUST00000058210.6
ENSMUST00000111878.1
epidermal growth factor receptor pathway substrate 8
chr17_-_24632608 0.57 ENSMUST00000097373.1
tuberous sclerosis 2
chr11_+_62847062 0.57 ENSMUST00000036085.4
F-box and WD-40 domain protein 10
chr4_-_46536096 0.57 ENSMUST00000102924.2
tripartite motif-containing 14
chr5_-_122900267 0.56 ENSMUST00000031435.7
lysine (K)-specific demethylase 2B
chr7_-_81454751 0.55 ENSMUST00000098331.3
ENSMUST00000178892.1
cytoplasmic polyadenylation element binding protein 1
chr5_-_148928619 0.53 ENSMUST00000149169.1
ENSMUST00000047257.8
katanin p60 subunit A-like 1
chr5_-_139819906 0.52 ENSMUST00000147328.1
transmembrane protein 184a
chr7_-_121035096 0.52 ENSMUST00000065740.2
predicted gene 9905
chr5_+_147269959 0.51 ENSMUST00000085591.5
pancreatic and duodenal homeobox 1
chr14_-_70443442 0.51 ENSMUST00000000793.5
polymerase (RNA) III (DNA directed) polypeptide D
chr1_+_167349976 0.50 ENSMUST00000028004.9
aldehyde dehydrogenase 9, subfamily A1
chr9_+_13662460 0.50 ENSMUST00000177755.1
mastermind like 2 (Drosophila)
chr9_-_107770945 0.48 ENSMUST00000183248.1
ENSMUST00000182022.1
ENSMUST00000035199.6
ENSMUST00000182659.1
RNA binding motif protein 5
chrX_-_74023908 0.48 ENSMUST00000033769.8
ENSMUST00000114352.1
ENSMUST00000068286.5
ENSMUST00000114360.3
ENSMUST00000114354.3
interleukin-1 receptor-associated kinase 1
chr4_-_126968124 0.48 ENSMUST00000106108.2
zinc finger, MYM-type 4
chr7_+_30650385 0.46 ENSMUST00000181529.1
predicted gene, 26610
chr9_+_109095427 0.46 ENSMUST00000072093.6
plexin B1
chr9_-_108578657 0.44 ENSMUST00000068700.5
WD repeat domain 6
chr12_-_31950535 0.44 ENSMUST00000172314.2
high mobility group box transcription factor 1
chr18_+_61555308 0.44 ENSMUST00000165721.1
ENSMUST00000115246.2
ENSMUST00000166990.1
ENSMUST00000163205.1
ENSMUST00000170862.1
casein kinase 1, alpha 1
chr17_-_34214459 0.43 ENSMUST00000121995.1
predicted gene 15821
chr1_+_167001417 0.43 ENSMUST00000165874.1
family with sequence similarity 78, member B
chr7_+_12881165 0.42 ENSMUST00000144578.1
zinc finger protein 128
chr17_-_24209377 0.42 ENSMUST00000024931.4
netrin 3
chr9_-_58158498 0.42 ENSMUST00000168864.2
immunoglobulin superfamily containing leucine-rich repeat
chr6_+_43265582 0.41 ENSMUST00000031750.7
Rho guanine nucleotide exchange factor (GEF) 5
chr18_+_61555258 0.41 ENSMUST00000165123.1
casein kinase 1, alpha 1
chr2_-_157566319 0.40 ENSMUST00000109528.2
ENSMUST00000088494.2
bladder cancer associated protein homolog (human)
chr3_+_28781305 0.38 ENSMUST00000060500.7
eukaryotic translation initiation factor 5A2
chr6_-_52158292 0.38 ENSMUST00000000964.5
ENSMUST00000120363.1
homeobox A1
chrX_-_141725181 0.37 ENSMUST00000067841.7
insulin receptor substrate 4
chr11_-_103344651 0.36 ENSMUST00000041385.7
Rho GTPase activating protein 27
chr11_-_94704499 0.36 ENSMUST00000069852.1
predicted gene 11541
chr11_+_73329727 0.35 ENSMUST00000092926.4
ENSMUST00000117445.1
spermatogenesis associated 22
chr19_+_27217357 0.35 ENSMUST00000047645.6
ENSMUST00000167487.1
very low density lipoprotein receptor
chrX_+_161717498 0.35 ENSMUST00000061514.7
retinoic acid induced 2
chr8_-_27174623 0.34 ENSMUST00000033878.6
ENSMUST00000054212.6
RAB11 family interacting protein 1 (class I)
chr3_+_107036156 0.34 ENSMUST00000052718.3
potassium voltage-gated channel, shaker-related subfamily, member 3
chr14_-_64949838 0.33 ENSMUST00000067843.3
ENSMUST00000176489.1
ENSMUST00000175905.1
ENSMUST00000022544.7
ENSMUST00000175744.1
ENSMUST00000176128.1
homeobox containing 1
chr12_-_31950210 0.32 ENSMUST00000176084.1
ENSMUST00000176103.1
ENSMUST00000167458.2
high mobility group box transcription factor 1
chr13_-_54611274 0.32 ENSMUST00000049575.7
clathrin, light polypeptide (Lcb)
chr18_-_38250157 0.29 ENSMUST00000181871.1
RIKEN cDNA 1700086O06 gene
chr10_+_42502030 0.29 ENSMUST00000105500.1
ENSMUST00000019939.5
sorting nexin 3
chr18_+_61555689 0.29 ENSMUST00000167187.1
casein kinase 1, alpha 1
chr13_-_54611332 0.28 ENSMUST00000091609.4
clathrin, light polypeptide (Lcb)
chr1_+_40681659 0.28 ENSMUST00000027231.7
solute carrier family 9 (sodium/hydrogen exchanger), member 2
chr3_+_105452326 0.28 ENSMUST00000098761.3
potassium voltage-gated channel, Shal-related family, member 3
chr17_+_68837062 0.28 ENSMUST00000178545.1
transmembrane protein 200C
chr7_-_144738520 0.28 ENSMUST00000118556.2
ENSMUST00000033393.8
anoctamin 1, calcium activated chloride channel
chr7_+_81571246 0.28 ENSMUST00000165460.1
WAS protein homolog associated with actin, golgi membranes and microtubules
chr7_-_144738478 0.27 ENSMUST00000121758.1
anoctamin 1, calcium activated chloride channel
chr8_+_10006656 0.27 ENSMUST00000033892.7
tumor necrosis factor (ligand) superfamily, member 13b
chr6_+_134920401 0.27 ENSMUST00000067327.4
ENSMUST00000003115.6
cyclin-dependent kinase inhibitor 1B
chr11_+_95712673 0.27 ENSMUST00000107717.1
zinc finger protein 652
chr2_+_121956411 0.26 ENSMUST00000110578.1
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
chr5_+_144190284 0.26 ENSMUST00000060747.7
basic helix-loop-helix family, member a15
chr2_+_71211706 0.26 ENSMUST00000112142.1
ENSMUST00000112139.1
ENSMUST00000112140.1
ENSMUST00000112138.1
dynein cytoplasmic 1 intermediate chain 2
chrX_+_161717055 0.26 ENSMUST00000112338.1
retinoic acid induced 2
chr11_+_117308135 0.25 ENSMUST00000153668.1
septin 9
chr1_-_164935522 0.25 ENSMUST00000027860.7
chemokine (C motif) ligand 1
chr4_+_103619580 0.25 ENSMUST00000106827.1
disabled 1
chr8_+_70754679 0.24 ENSMUST00000110093.2
ENSMUST00000143118.1
ENSMUST00000034301.5
ENSMUST00000110090.1
RAB3A, member RAS oncogene family
chr15_+_78899755 0.24 ENSMUST00000001226.3
ENSMUST00000061239.7
ENSMUST00000109698.2
SH3-domain binding protein 1
chr9_+_100643755 0.24 ENSMUST00000133388.1
stromal antigen 1
chr11_+_72796164 0.23 ENSMUST00000172220.1
zinc finger, ZZ-type with EF hand domain 1
chr7_+_35119285 0.23 ENSMUST00000042985.9
CCAAT/enhancer binding protein (C/EBP), alpha
chr19_-_8880883 0.22 ENSMUST00000096253.5
expressed sequence AI462493
chr8_-_13890233 0.22 ENSMUST00000033839.7
coordinator of PRMT5, differentiation stimulator
chr12_-_31950170 0.22 ENSMUST00000176520.1
high mobility group box transcription factor 1
chr5_-_137786681 0.22 ENSMUST00000132726.1
methylphosphate capping enzyme
chr9_-_43239816 0.22 ENSMUST00000034512.5
OAF homolog (Drosophila)
chr11_+_72796254 0.21 ENSMUST00000069395.5
zinc finger, ZZ-type with EF hand domain 1
chr18_-_38250558 0.20 ENSMUST00000181757.1
RIKEN cDNA 1700086O06 gene
chr6_+_113471427 0.19 ENSMUST00000058300.7
interleukin 17 receptor C
chr17_+_28691342 0.19 ENSMUST00000114758.1
ENSMUST00000004990.6
ENSMUST00000062694.8
ENSMUST00000114754.1
mitogen-activated protein kinase 14
chr2_-_37703275 0.19 ENSMUST00000072186.5
spermatid perinuclear RNA binding protein
chr6_+_135197977 0.17 ENSMUST00000111915.1
ENSMUST00000111916.1
RIKEN cDNA 8430419L09 gene
chr11_+_32455362 0.17 ENSMUST00000051053.4
ubiquitin domain containing 2
chr3_-_135608221 0.17 ENSMUST00000132668.1
nuclear factor of kappa light polypeptide gene enhancer in B cells 1, p105
chr7_-_16286744 0.17 ENSMUST00000150528.2
ENSMUST00000118976.2
ENSMUST00000146609.2
coiled-coil domain containing 9
chr13_+_5861489 0.16 ENSMUST00000000080.6
Kruppel-like factor 6
chr5_-_137786651 0.16 ENSMUST00000031740.9
methylphosphate capping enzyme
chr7_+_126928844 0.16 ENSMUST00000032924.5
potassium channel tetramerisation domain containing 13
chr9_+_45055166 0.16 ENSMUST00000114664.1
ENSMUST00000093856.3
myelin protein zero-like 3
chr2_+_160731684 0.15 ENSMUST00000174885.1
ENSMUST00000109462.1
phospholipase C, gamma 1
chr18_+_38250240 0.15 ENSMUST00000025314.5
RIKEN cDNA 0610009O20 gene
chr9_+_50856924 0.14 ENSMUST00000174628.1
ENSMUST00000034560.7
ENSMUST00000114437.2
ENSMUST00000175645.1
ENSMUST00000176349.1
ENSMUST00000176798.1
ENSMUST00000175640.1
protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), beta isoform
chr7_+_141328122 0.14 ENSMUST00000133012.1
ENSMUST00000026578.7
transmembrane protein 80
chr19_+_27217011 0.13 ENSMUST00000164746.1
ENSMUST00000172302.1
very low density lipoprotein receptor
chr17_-_84187939 0.13 ENSMUST00000060366.6
zinc finger protein 36, C3H type-like 2
chr1_-_51915901 0.13 ENSMUST00000018561.7
ENSMUST00000114537.2
myosin IB
chr8_+_107436355 0.13 ENSMUST00000166615.1
WW domain containing E3 ubiquitin protein ligase 2
chr1_+_55406163 0.12 ENSMUST00000042986.8
phospholipase C-like 1
chr1_-_175625580 0.12 ENSMUST00000027810.7
fumarate hydratase 1
chr7_+_121707189 0.12 ENSMUST00000065310.2
RIKEN cDNA 1700069B07 gene
chr7_+_141327840 0.12 ENSMUST00000126510.1
ENSMUST00000145184.1
transmembrane protein 80
chr4_+_155831272 0.10 ENSMUST00000139651.1
ENSMUST00000084097.5
aurora kinase A interacting protein 1
chrX_-_9662950 0.10 ENSMUST00000033519.2
dynein light chain Tctex-type 3
chr11_-_42000532 0.09 ENSMUST00000070735.3
gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2
chr4_+_155831630 0.08 ENSMUST00000105592.1
ENSMUST00000105591.1
aurora kinase A interacting protein 1
chr4_-_126256226 0.08 ENSMUST00000122129.1
ENSMUST00000061143.8
ENSMUST00000106132.2
MAP7 domain containing 1
chr11_-_68871848 0.08 ENSMUST00000101017.2
nuclear distribution gene E-like homolog 1 (A. nidulans)
chr7_-_65371210 0.07 ENSMUST00000102592.3
tight junction protein 1
chr17_-_25497288 0.07 ENSMUST00000165183.2
ENSMUST00000051864.4
somatostatin receptor 5
chr2_-_120609319 0.06 ENSMUST00000102497.3
leucine rich repeat containing 57
chr10_-_99126321 0.05 ENSMUST00000060761.5
per-hexamer repeat gene 2
chr1_-_51915968 0.05 ENSMUST00000046390.7
myosin IB
chr2_-_120609500 0.04 ENSMUST00000133612.1
ENSMUST00000102498.1
ENSMUST00000102499.1
leucine rich repeat containing 57
chr2_-_120609283 0.04 ENSMUST00000102496.1
leucine rich repeat containing 57
chr4_-_19708922 0.02 ENSMUST00000108246.2
WW domain containing E3 ubiquitin protein ligase 1
chr5_-_24527276 0.02 ENSMUST00000088311.4
gastrulation brain homeobox 1
chr4_+_121039385 0.02 ENSMUST00000030372.5
collagen, type IX, alpha 2
chr16_-_20302358 0.01 ENSMUST00000048642.8
presenilin associated, rhomboid-like
chr14_+_64950037 0.00 ENSMUST00000043914.5
integrator complex subunit 9
chr4_+_117096049 0.00 ENSMUST00000030443.5
patched homolog 2
chr11_-_42000284 0.00 ENSMUST00000109292.2
ENSMUST00000109290.1
gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2

Network of associatons between targets according to the STRING database.

First level regulatory network of Gli2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.4 GO:0046022 regulation of transcription from RNA polymerase II promoter, mitotic(GO:0046021) positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022)
0.5 3.2 GO:0003383 apical constriction(GO:0003383)
0.3 1.2 GO:0002415 immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
0.3 0.8 GO:0031959 mineralocorticoid receptor signaling pathway(GO:0031959)
0.3 0.8 GO:2000097 regulation of lipoprotein oxidation(GO:0034442) negative regulation of lipoprotein oxidation(GO:0034443) regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.2 0.7 GO:0070782 phosphatidylserine exposure on apoptotic cell surface(GO:0070782)
0.2 0.9 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.2 0.6 GO:0036118 hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.1 0.6 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.1 0.6 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.1 1.7 GO:2000465 regulation of glycogen (starch) synthase activity(GO:2000465)
0.1 0.6 GO:0021993 initiation of neural tube closure(GO:0021993)
0.1 0.3 GO:2000563 positive regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000563)
0.1 0.7 GO:0003431 growth plate cartilage chondrocyte development(GO:0003431)
0.1 0.4 GO:0000711 meiotic DNA repair synthesis(GO:0000711)
0.1 0.5 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.1 1.1 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.1 0.4 GO:0002408 myeloid dendritic cell chemotaxis(GO:0002408)
0.1 0.5 GO:0009730 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.1 0.3 GO:2000642 intralumenal vesicle formation(GO:0070676) negative regulation of early endosome to late endosome transport(GO:2000642)
0.1 0.5 GO:0034436 glycoprotein transport(GO:0034436)
0.1 0.3 GO:0031296 B cell costimulation(GO:0031296)
0.1 0.5 GO:0018992 germ-line sex determination(GO:0018992)
0.1 0.2 GO:0021589 hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589)
0.1 0.2 GO:0050975 sensory perception of touch(GO:0050975)
0.1 1.0 GO:0010745 negative regulation of macrophage derived foam cell differentiation(GO:0010745)
0.1 1.1 GO:1904424 regulation of GTP binding(GO:1904424)
0.1 0.4 GO:0051013 microtubule severing(GO:0051013)
0.1 0.6 GO:0015705 iodide transport(GO:0015705)
0.1 0.5 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.1 0.3 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.1 0.7 GO:1902474 positive regulation of protein localization to synapse(GO:1902474)
0.1 0.4 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.1 0.4 GO:0021571 rhombomere 5 development(GO:0021571)
0.1 0.5 GO:0071285 cellular response to lithium ion(GO:0071285)
0.1 1.3 GO:0032897 negative regulation of viral transcription(GO:0032897)
0.0 1.1 GO:0032933 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.0 0.5 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.2 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.0 0.9 GO:0071392 cellular response to estradiol stimulus(GO:0071392)
0.0 0.2 GO:1903416 response to glycoside(GO:1903416)
0.0 1.1 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.0 1.0 GO:0002091 negative regulation of receptor internalization(GO:0002091)
0.0 0.1 GO:0006106 fumarate metabolic process(GO:0006106)
0.0 1.0 GO:0044247 glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.0 0.4 GO:0035562 negative regulation of chromatin binding(GO:0035562)
0.0 0.5 GO:0042136 neurotransmitter biosynthetic process(GO:0042136)
0.0 0.3 GO:0097623 potassium ion export across plasma membrane(GO:0097623)
0.0 0.3 GO:0098719 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.3 GO:0051127 positive regulation of actin nucleation(GO:0051127)
0.0 0.3 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.1 GO:1904628 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.0 0.1 GO:1900122 positive regulation of receptor binding(GO:1900122)
0.0 0.5 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.0 0.1 GO:0014835 myoblast differentiation involved in skeletal muscle regeneration(GO:0014835) positive regulation of interleukin-12 secretion(GO:2001184)
0.0 0.7 GO:0006826 iron ion transport(GO:0006826)
0.0 0.4 GO:0030262 apoptotic nuclear changes(GO:0030262)
0.0 0.2 GO:1901339 inositol trisphosphate biosynthetic process(GO:0032959) regulation of store-operated calcium channel activity(GO:1901339)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.2 GO:0033269 internode region of axon(GO:0033269)
0.2 0.6 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.1 0.2 GO:0036488 CHOP-C/EBP complex(GO:0036488)
0.1 1.1 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.1 0.7 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 0.6 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0 0.3 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.5 GO:0072687 meiotic spindle(GO:0072687)
0.0 0.6 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 1.2 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.9 GO:0033270 paranode region of axon(GO:0033270)
0.0 1.3 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.5 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.5 GO:0034385 very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.0 0.3 GO:0032009 early phagosome(GO:0032009)
0.0 1.2 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.1 GO:0060053 neurofilament cytoskeleton(GO:0060053)
0.0 0.2 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.3 GO:0031105 septin complex(GO:0031105)
0.0 1.2 GO:0030667 secretory granule membrane(GO:0030667)
0.0 0.3 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:2001069 glycogen binding(GO:2001069)
0.3 0.8 GO:0017082 mineralocorticoid receptor activity(GO:0017082)
0.2 1.0 GO:0008184 glycogen phosphorylase activity(GO:0008184)
0.2 1.0 GO:0004994 somatostatin receptor activity(GO:0004994)
0.2 0.5 GO:0034437 very-low-density lipoprotein particle binding(GO:0034189) glycoprotein transporter activity(GO:0034437)
0.1 0.9 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.1 0.6 GO:0004415 hyalurononglucosaminidase activity(GO:0004415)
0.1 0.6 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
0.1 0.5 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.1 0.5 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.1 3.5 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.1 0.6 GO:1990715 mRNA CDS binding(GO:1990715)
0.1 0.7 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.1 0.3 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.1 0.6 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 0.7 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.7 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 1.0 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.3 GO:0003964 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0 0.5 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.3 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.6 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 1.9 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.4 GO:0043560 insulin receptor substrate binding(GO:0043560)
0.0 0.2 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.0 1.3 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.5 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 0.5 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.3 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.3 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 2.4 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.3 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.6 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.4 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.1 GO:0070012 oligopeptidase activity(GO:0070012)
0.0 0.2 GO:0001013 RNA polymerase I regulatory region DNA binding(GO:0001013)
0.0 0.3 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.6 GO:0043548 phosphatidylinositol 3-kinase binding(GO:0043548)
0.0 0.1 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 1.5 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.4 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 1.1 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 3.6 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 0.8 PID AURORA A PATHWAY Aurora A signaling
0.0 0.7 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 1.7 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.6 PID ARF 3PATHWAY Arf1 pathway
0.0 0.4 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.5 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.2 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 0.8 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.6 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.7 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.2 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.1 1.3 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.1 0.6 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 1.0 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.5 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.0 0.6 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.6 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 1.3 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.0 0.5 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 2.0 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.5 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.2 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0 0.3 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.2 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.5 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.5 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.5 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.4 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 0.8 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation