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2D miR_HR1_12

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Results for Nr1h2

Z-value: 0.87

Motif logo

Transcription factors associated with Nr1h2

Gene Symbol Gene ID Gene Info
ENSMUSG00000060601.6 nuclear receptor subfamily 1, group H, member 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Nr1h2mm10_v2_chr7_-_44553901_44553955-0.019.7e-01Click!

Activity profile of Nr1h2 motif

Sorted Z-values of Nr1h2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr5_-_100159261 1.55 ENSMUST00000139520.1
transmembrane protein 150C
chr4_-_53159885 1.16 ENSMUST00000030010.3
ATP-binding cassette, sub-family A (ABC1), member 1
chr7_+_97453204 0.99 ENSMUST00000050732.7
ENSMUST00000121987.1
potassium channel tetramerisation domain containing 14
chr1_+_58711488 0.90 ENSMUST00000097722.2
ENSMUST00000114313.1
CASP8 and FADD-like apoptosis regulator
chr4_+_40472180 0.90 ENSMUST00000049655.2
transmembrane protein 215
chr7_-_46238464 0.90 ENSMUST00000154292.2
ENSMUST00000078680.6
ENSMUST00000177212.1
ENSMUST00000009667.5
Usher syndrome 1C
chr1_+_131599239 0.87 ENSMUST00000027690.6
arginine vasopressin receptor 1B
chr4_+_43641262 0.86 ENSMUST00000123351.1
ENSMUST00000128549.1
natriuretic peptide receptor 2
chr11_-_60210410 0.85 ENSMUST00000144942.1
sterol regulatory element binding transcription factor 1
chr19_-_5845471 0.84 ENSMUST00000174287.1
ENSMUST00000173672.1
nuclear paraspeckle assembly transcript 1 (non-protein coding)
chr4_-_42168603 0.81 ENSMUST00000098121.3
predicted gene 13305
chr7_+_112953955 0.80 ENSMUST00000182858.1
Ras association (RalGDS/AF-6) domain family (N-terminal) member 10
chr10_-_81600857 0.79 ENSMUST00000151858.1
ENSMUST00000142948.1
ENSMUST00000072020.2
transducin-like enhancer of split 6, homolog of Drosophila E(spl)
chr2_+_155381808 0.77 ENSMUST00000043237.7
ENSMUST00000174685.1
transformation related protein 53 inducible nuclear protein 2
chr2_-_113829069 0.75 ENSMUST00000024005.7
secretogranin V
chr4_-_63154130 0.75 ENSMUST00000030041.4
alpha 1 microglobulin/bikunin
chr3_+_3508024 0.72 ENSMUST00000108393.1
ENSMUST00000017832.8
hepatocyte nuclear factor 4, gamma
chr19_+_42247544 0.68 ENSMUST00000122375.1
golgi autoantigen, golgin subfamily a, 7B
chr12_-_110978943 0.61 ENSMUST00000142012.1
ankyrin repeat domain 9
chr4_-_129440800 0.61 ENSMUST00000053042.5
ENSMUST00000106046.1
zinc finger and BTB domain containing 8b
chr17_-_56218881 0.60 ENSMUST00000038794.4
dipeptidylpeptidase 9
chr3_+_90514435 0.59 ENSMUST00000048138.6
ENSMUST00000181271.1
S100 calcium binding protein A13
chr14_-_72602945 0.58 ENSMUST00000162825.1
fibronectin type III domain containing 3A
chr12_-_110978981 0.58 ENSMUST00000135131.1
ENSMUST00000043459.6
ENSMUST00000128353.1
ankyrin repeat domain 9
chr4_+_123859651 0.58 ENSMUST00000097896.2
Riken cDNA 4933427I04 gene
chr9_+_37208291 0.57 ENSMUST00000034632.8
transmembrane protein 218
chr7_-_19770509 0.57 ENSMUST00000003061.7
basal cell adhesion molecule
chr5_+_117363513 0.56 ENSMUST00000111959.1
WD repeat and SOCS box-containing 2
chr1_-_131276914 0.56 ENSMUST00000161764.1
inhibitor of kappaB kinase epsilon
chr11_-_98400453 0.56 ENSMUST00000090827.5
post-GPI attachment to proteins 3
chr5_+_123015010 0.55 ENSMUST00000121652.1
ENSMUST00000051016.4
ORAI calcium release-activated calcium modulator 1
chr5_+_117357274 0.55 ENSMUST00000031309.9
WD repeat and SOCS box-containing 2
chr2_+_131210501 0.54 ENSMUST00000110206.1
adaptor-related protein 5 complex, sigma 1 subunit
chr16_+_96205719 0.53 ENSMUST00000129904.1
SH3-binding domain glutamic acid-rich protein
chr6_+_88902251 0.53 ENSMUST00000055022.8
transmembrane protein, adipocyte asscociated 1
chr4_-_152038568 0.50 ENSMUST00000030792.1
taste receptor, type 1, member 1
chr11_+_29718563 0.50 ENSMUST00000060992.5
reticulon 4
chr2_+_155382186 0.49 ENSMUST00000134218.1
transformation related protein 53 inducible nuclear protein 2
chr6_+_125320633 0.49 ENSMUST00000176655.1
ENSMUST00000176110.1
sodium channel, nonvoltage-gated 1 alpha
chr5_+_115466234 0.49 ENSMUST00000145785.1
ENSMUST00000031495.4
ENSMUST00000112071.1
ENSMUST00000125568.1
phospholipase A2, group IB, pancreas
chr13_-_12461432 0.49 ENSMUST00000143693.1
ENSMUST00000144283.1
ENSMUST00000099820.3
ENSMUST00000135166.1
lectin, galactose binding, soluble 8
chr19_-_46672883 0.48 ENSMUST00000026012.7
cytochrome P450, family 17, subfamily a, polypeptide 1
chr5_-_146185304 0.47 ENSMUST00000073721.5
RIKEN cDNA 1700001J03 gene
chr11_-_103697898 0.47 ENSMUST00000021329.7
golgi SNAP receptor complex member 2
chr12_-_87233556 0.46 ENSMUST00000021423.7
NADP+ dependent oxidoreductase domain containing 1
chr11_-_101119889 0.45 ENSMUST00000017946.5
family with sequence similarity 134, member C
chr7_+_81523531 0.45 ENSMUST00000181903.1
RIKEN cDNA 2900076A07 gene
chr2_+_30266721 0.45 ENSMUST00000113645.1
ENSMUST00000133877.1
ENSMUST00000139719.1
ENSMUST00000113643.1
ENSMUST00000150695.1
phytanoyl-CoA dioxygenase domain containing 1
chr10_-_109823585 0.45 ENSMUST00000161582.1
neuron navigator 3
chr3_-_59635733 0.45 ENSMUST00000177879.1
predicted gene 5709
chr10_-_60938123 0.45 ENSMUST00000036304.3
polymorphic derived intron containing
chr11_-_30025915 0.45 ENSMUST00000058902.5
echinoderm microtubule associated protein like 6
chr2_-_65238625 0.44 ENSMUST00000112429.2
ENSMUST00000102726.1
ENSMUST00000112430.1
Cobl-like 1
chr18_+_37333853 0.44 ENSMUST00000061717.2
protocadherin beta 6
chr2_-_65238573 0.42 ENSMUST00000090896.3
ENSMUST00000155082.1
Cobl-like 1
chr1_-_164458345 0.42 ENSMUST00000027863.7
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr2_+_131210363 0.41 ENSMUST00000110210.1
ENSMUST00000089506.5
ENSMUST00000110208.1
adaptor-related protein 5 complex, sigma 1 subunit
chr5_+_130219706 0.41 ENSMUST00000065329.6
transmembrane protein 248
chr7_-_27446599 0.41 ENSMUST00000011895.7
spectrin beta, non-erythrocytic 4
chr15_+_78877172 0.40 ENSMUST00000041587.7
golgi associated, gamma adaptin ear containing, ARF binding protein 1
chr8_-_84237042 0.39 ENSMUST00000039480.5
zinc finger SWIM-type containing 4
chr3_-_89245829 0.39 ENSMUST00000041022.8
tripartite motif-containing 46
chr11_+_55098104 0.39 ENSMUST00000000608.7
GM2 ganglioside activator protein
chr17_-_56716788 0.38 ENSMUST00000067931.5
vimentin-type intermediate filament associated coiled-coil protein
chr5_+_107331157 0.38 ENSMUST00000031215.8
ENSMUST00000112677.3
bromodomain, testis-specific
chr10_-_68541842 0.37 ENSMUST00000020103.2
RIKEN cDNA 1700040L02 gene
chr5_+_124328083 0.36 ENSMUST00000111477.1
ENSMUST00000077376.2
RIKEN cDNA 2810006K23 gene
chr17_-_83846769 0.35 ENSMUST00000000687.7
3-hydroxyanthranilate 3,4-dioxygenase
chr6_-_134632388 0.35 ENSMUST00000047443.3
MANSC domain containing 1
chr11_-_101119814 0.34 ENSMUST00000107295.3
family with sequence similarity 134, member C
chr11_-_102556122 0.32 ENSMUST00000143842.1
G patch domain containing 8
chr3_-_116423930 0.32 ENSMUST00000106491.2
CDC14 cell division cycle 14A
chr2_+_156420837 0.32 ENSMUST00000103137.3
erythrocyte protein band 4.1-like 1
chr3_-_116424007 0.31 ENSMUST00000090464.4
CDC14 cell division cycle 14A
chr11_+_115834314 0.31 ENSMUST00000173289.1
ENSMUST00000137900.1
lethal giant larvae homolog 2 (Drosophila)
chr2_-_13793793 0.30 ENSMUST00000003509.8
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6
chrX_-_53608979 0.30 ENSMUST00000123034.1
predicted gene 14597
chr7_+_81523555 0.29 ENSMUST00000180385.1
ENSMUST00000180879.1
ENSMUST00000181164.1
ENSMUST00000181264.1
RIKEN cDNA 2900076A07 gene
chr6_+_90462562 0.29 ENSMUST00000032174.5
Kruppel-like factor 15
chr15_+_85832301 0.28 ENSMUST00000146088.1
tetratricopeptide repeat domain 38
chr3_-_148989316 0.28 ENSMUST00000098518.2
latrophilin 2
chr2_+_156421048 0.27 ENSMUST00000109574.1
erythrocyte protein band 4.1-like 1
chr5_-_122779278 0.26 ENSMUST00000111668.3
calcium/calmodulin-dependent protein kinase kinase 2, beta
chr17_-_25985641 0.26 ENSMUST00000041641.8
calpain 15
chr11_+_78245743 0.26 ENSMUST00000002133.8
stromal cell derived factor 2
chr5_-_120777628 0.25 ENSMUST00000044833.8
2'-5' oligoadenylate synthetase 3
chr15_+_65787023 0.25 ENSMUST00000015146.9
ENSMUST00000173858.1
ENSMUST00000172756.1
ENSMUST00000174856.1
EFR3 homolog A (S. cerevisiae)
chr9_+_46240696 0.24 ENSMUST00000034585.6
apolipoprotein A-IV
chr8_+_4238815 0.24 ENSMUST00000003027.7
ENSMUST00000110999.1
mitogen-activated protein kinase kinase 7
chr17_+_49428359 0.23 ENSMUST00000165390.2
ENSMUST00000024797.9
ENSMUST00000173033.1
molybdenum cofactor synthesis 1
chr10_+_21993890 0.23 ENSMUST00000092673.4
serum/glucocorticoid regulated kinase 1
chr3_-_95241598 0.23 ENSMUST00000090815.5
ENSMUST00000107197.1
predicted gene 128
chr16_+_17894197 0.23 ENSMUST00000046937.2
testis-specific serine kinase 1
chr2_+_156421083 0.23 ENSMUST00000125153.2
ENSMUST00000103136.1
ENSMUST00000109577.2
erythrocyte protein band 4.1-like 1
chr7_-_25718976 0.22 ENSMUST00000002683.2
coiled-coil domain containing 97
chr7_+_45335256 0.21 ENSMUST00000085351.4
histidine rich calcium binding protein
chr15_-_89425795 0.21 ENSMUST00000168376.1
carnitine palmitoyltransferase 1b, muscle
chr2_+_131491764 0.20 ENSMUST00000028806.5
ENSMUST00000110179.2
ENSMUST00000110189.2
ENSMUST00000110182.2
ENSMUST00000110183.2
ENSMUST00000110186.2
ENSMUST00000110188.1
spermine oxidase
chr8_+_4238733 0.20 ENSMUST00000110998.2
ENSMUST00000062686.4
mitogen-activated protein kinase kinase 7
chr3_+_146597077 0.19 ENSMUST00000029837.7
ENSMUST00000121133.1
urate oxidase
chr14_-_20730327 0.19 ENSMUST00000047490.5
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 2
chr4_-_46389391 0.19 ENSMUST00000086563.4
ENSMUST00000030015.5
RIKEN cDNA 5830415F09 gene
chr2_+_61593125 0.19 ENSMUST00000112494.1
TRAF family member-associated Nf-kappa B activator
chr11_+_93996082 0.18 ENSMUST00000041956.7
sperm associated antigen 9
chr7_-_47528862 0.18 ENSMUST00000172559.1
MAS-related GPR, member A2B
chr12_-_21286176 0.18 ENSMUST00000172834.1
ENSMUST00000076260.4
integrin beta 1 binding protein 1
chr5_-_124327883 0.18 ENSMUST00000031344.6
M-phase phosphoprotein 9
chr12_-_21286097 0.18 ENSMUST00000173729.1
integrin beta 1 binding protein 1
chr7_+_27862557 0.18 ENSMUST00000053722.8
zinc finger proten 607
chr2_+_30266513 0.17 ENSMUST00000091132.6
phytanoyl-CoA dioxygenase domain containing 1
chr9_-_35199877 0.17 ENSMUST00000176021.1
ENSMUST00000176531.1
ENSMUST00000176685.1
ENSMUST00000177129.1
toll-interleukin 1 receptor (TIR) domain-containing adaptor protein
chr2_+_61593077 0.17 ENSMUST00000112495.1
ENSMUST00000112501.2
TRAF family member-associated Nf-kappa B activator
chr4_+_123917420 0.17 ENSMUST00000030399.6
Ras-related GTP binding C
chr11_-_69948145 0.17 ENSMUST00000179298.1
ENSMUST00000018710.6
ENSMUST00000135437.1
ENSMUST00000141837.2
ENSMUST00000142500.1
solute carrier family 2 (facilitated glucose transporter), member 4
chrX_-_155216338 0.17 ENSMUST00000112551.3
spermidine/spermine N1-acetyl transferase 1
chr12_-_87147883 0.17 ENSMUST00000037788.4
protein-O-mannosyltransferase 2
chr2_-_26604267 0.16 ENSMUST00000028286.5
1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta)
chr15_-_83251720 0.16 ENSMUST00000164614.1
ENSMUST00000049530.6
alpha 1,4-galactosyltransferase
chr12_-_111813834 0.16 ENSMUST00000021715.5
X-ray repair complementing defective repair in Chinese hamster cells 3
chrX_-_155216444 0.15 ENSMUST00000026318.8
spermidine/spermine N1-acetyl transferase 1
chr13_+_102693596 0.15 ENSMUST00000172138.1
CD180 antigen
chr2_+_155276297 0.15 ENSMUST00000029128.3
microtubule-associated protein 1 light chain 3 alpha
chr6_+_124663027 0.15 ENSMUST00000004381.7
lysophosphatidylcholine acyltransferase 3
chr5_+_103754154 0.15 ENSMUST00000054979.3
AF4/FMR2 family, member 1
chr9_-_63399216 0.15 ENSMUST00000168665.1
RIKEN cDNA 2300009A05 gene
chrX_-_102644210 0.14 ENSMUST00000052012.7
ENSMUST00000043596.5
ENSMUST00000119229.1
ENSMUST00000122022.1
ENSMUST00000120270.1
ENSMUST00000113611.2
phosphorylase kinase alpha 1
chr14_-_50924626 0.13 ENSMUST00000160375.1
ENSMUST00000162177.1
ENSMUST00000159292.1
O-sialoglycoprotein endopeptidase
chr6_+_142756680 0.13 ENSMUST00000032419.8
cytidine monophospho-N-acetylneuraminic acid synthetase
chr11_-_83530505 0.13 ENSMUST00000035938.2
chemokine (C-C motif) ligand 5
chr14_+_75016027 0.13 ENSMUST00000036072.7
RIKEN cDNA 5031414D18 gene
chr4_-_119422355 0.13 ENSMUST00000106316.1
ENSMUST00000030385.6
phosphopantothenoylcysteine synthetase
chr1_+_132506230 0.12 ENSMUST00000058167.1
transmembrane protein 81
chr1_+_6214627 0.11 ENSMUST00000027040.6
RB1-inducible coiled-coil 1
chr15_+_74714832 0.11 ENSMUST00000023265.3
prostate stem cell antigen
chr12_+_87147703 0.11 ENSMUST00000063117.8
glutathione transferase zeta 1 (maleylacetoacetate isomerase)
chr2_-_157571270 0.10 ENSMUST00000173378.1
bladder cancer associated protein homolog (human)
chr4_+_119422806 0.10 ENSMUST00000094819.4
zinc finger, MYND domain containing 12
chr11_+_85171096 0.10 ENSMUST00000018623.3
RIKEN cDNA 1700125H20 gene
chr15_-_79328154 0.10 ENSMUST00000166977.2
phospholipase A2, group VI
chr4_+_120532219 0.09 ENSMUST00000062990.3
schlafen like 1
chr15_-_79328201 0.09 ENSMUST00000173163.1
ENSMUST00000047816.8
ENSMUST00000172403.2
ENSMUST00000173632.1
phospholipase A2, group VI
chr11_+_58963790 0.09 ENSMUST00000075141.6
tripartite motif-containing 17
chr9_+_77941274 0.09 ENSMUST00000134072.1
ELOVL family member 5, elongation of long chain fatty acids (yeast)
chr8_-_122360746 0.08 ENSMUST00000044123.1
thyrotropin releasing hormone receptor 2
chr10_+_61417972 0.08 ENSMUST00000049339.6
nodal
chr7_+_114768736 0.08 ENSMUST00000117543.1
inscuteable homolog (Drosophila)
chr2_-_164911586 0.08 ENSMUST00000041361.7
zinc finger protein 335
chr3_+_89246397 0.07 ENSMUST00000168900.1
keratinocyte associated protein 2
chr1_+_135729147 0.07 ENSMUST00000027677.7
cysteine and glycine-rich protein 1
chr3_+_89245952 0.06 ENSMUST00000040888.5
keratinocyte associated protein 2
chr14_+_54686171 0.06 ENSMUST00000038539.6
RIKEN cDNA 1700123O20 gene
chr5_+_67306941 0.06 ENSMUST00000162372.1
ENSMUST00000113676.2
solute carrier family 30 (zinc transporter), member 9
chr5_-_136565432 0.06 ENSMUST00000176172.1
cut-like homeobox 1
chr6_+_54429603 0.06 ENSMUST00000132855.1
ENSMUST00000126637.1
WAS/WASL interacting protein family, member 3
chr8_-_36249292 0.05 ENSMUST00000065297.5
LON peptidase N-terminal domain and ring finger 1
chr16_+_87784075 0.05 ENSMUST00000069809.4
RIKEN cDNA 2810407A14 gene
chr14_+_50944499 0.04 ENSMUST00000178092.1
purine-nucleoside phosphorylase
chr12_+_108792946 0.04 ENSMUST00000021692.7
YY1 transcription factor
chr8_+_14095849 0.04 ENSMUST00000152652.1
ENSMUST00000133298.1
discs, large (Drosophila) homolog-associated protein 2
chr4_-_44167580 0.04 ENSMUST00000098098.2
ring finger protein 38
chr6_-_40585783 0.03 ENSMUST00000177178.1
ENSMUST00000129948.2
ENSMUST00000101491.4
C-type lectin domain family 5, member a
chr1_+_38987806 0.03 ENSMUST00000027247.5
phosducin-like 3
chr11_+_101732950 0.02 ENSMUST00000039152.7
DEAH (Asp-Glu-Ala-His) box polypeptide 8
chr1_+_33719863 0.01 ENSMUST00000088287.3
RAB23, member RAS oncogene family
chr12_+_21286297 0.01 ENSMUST00000067284.8
cleavage and polyadenylation specificity factor 3
chr1_+_153652943 0.00 ENSMUST00000041776.5
regulator of G-protein signaling 8
chr9_-_42472198 0.00 ENSMUST00000128959.1
ENSMUST00000066148.5
ENSMUST00000138506.1
tubulin folding cofactor E-like
chr19_+_46707443 0.00 ENSMUST00000003655.7
arsenic (+3 oxidation state) methyltransferase
chr17_-_65540747 0.00 ENSMUST00000062161.6
transmembrane protein 232

Network of associatons between targets according to the STRING database.

First level regulatory network of Nr1h2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.2 GO:0060155 response to high density lipoprotein particle(GO:0055099) platelet dense granule organization(GO:0060155)
0.2 0.7 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.2 0.9 GO:0014732 skeletal muscle atrophy(GO:0014732) negative regulation of myoblast fusion(GO:1901740) regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.2 0.9 GO:0001992 regulation of systemic arterial blood pressure by vasopressin(GO:0001992)
0.2 0.9 GO:1904970 brush border assembly(GO:1904970)
0.1 0.4 GO:1903279 regulation of calcium:sodium antiporter activity(GO:1903279)
0.1 0.3 GO:0032917 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.1 0.5 GO:0050917 sensory perception of umami taste(GO:0050917)
0.1 0.2 GO:0002002 regulation of angiotensin levels in blood(GO:0002002)
0.1 0.8 GO:0003062 regulation of heart rate by chemical signal(GO:0003062)
0.1 0.4 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.1 0.4 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.1 0.9 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168) negative regulation of oocyte maturation(GO:1900194)
0.1 0.6 GO:0050703 interleukin-1 alpha secretion(GO:0050703)
0.1 0.5 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.1 0.5 GO:0002317 plasma cell differentiation(GO:0002317)
0.1 0.3 GO:0016332 establishment or maintenance of polarity of embryonic epithelium(GO:0016332)
0.1 0.9 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.1 0.7 GO:0018298 protein-chromophore linkage(GO:0018298)
0.1 0.2 GO:0046208 spermine catabolic process(GO:0046208)
0.1 0.3 GO:0061762 CAMKK-AMPK signaling cascade(GO:0061762)
0.1 0.5 GO:0006561 proline biosynthetic process(GO:0006561)
0.1 0.6 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.1 0.7 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.1 0.2 GO:1904100 regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
0.1 0.4 GO:0009313 ganglioside catabolic process(GO:0006689) oligosaccharide catabolic process(GO:0009313)
0.1 0.5 GO:0040016 embryonic cleavage(GO:0040016)
0.1 0.4 GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
0.1 0.4 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.4 GO:0046874 quinolinate metabolic process(GO:0046874)
0.0 0.2 GO:0072566 chemokine (C-X-C motif) ligand 1 production(GO:0072566) regulation of chemokine (C-X-C motif) ligand 1 production(GO:2000338)
0.0 0.2 GO:0019720 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720)
0.0 0.8 GO:0030575 nuclear body organization(GO:0030575)
0.0 0.4 GO:2000671 regulation of motor neuron apoptotic process(GO:2000671)
0.0 0.5 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 0.1 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.0 0.9 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.1 GO:0046381 CMP-N-acetylneuraminate metabolic process(GO:0046381)
0.0 0.1 GO:2000503 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634) positive regulation of natural killer cell chemotaxis(GO:2000503)
0.0 0.2 GO:0060700 regulation of ribonuclease activity(GO:0060700)
0.0 0.2 GO:0090238 positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of arachidonic acid secretion(GO:0090238) positive regulation of ceramide biosynthetic process(GO:2000304)
0.0 0.5 GO:0042448 progesterone metabolic process(GO:0042448)
0.0 0.8 GO:0016486 peptide hormone processing(GO:0016486)
0.0 0.5 GO:0002115 store-operated calcium entry(GO:0002115)
0.0 0.2 GO:0001575 globoside metabolic process(GO:0001575)
0.0 0.1 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.2 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.0 0.3 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.2 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.0 0.3 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.0 0.4 GO:0099612 protein localization to axon(GO:0099612)
0.0 0.6 GO:0060009 Sertoli cell development(GO:0060009)
0.0 0.2 GO:0046415 urate metabolic process(GO:0046415)
0.0 0.3 GO:0007141 male meiosis I(GO:0007141)
0.0 0.1 GO:0030242 pexophagy(GO:0030242)
0.0 0.2 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.0 0.3 GO:0072311 renal filtration cell differentiation(GO:0061318) glomerular visceral epithelial cell differentiation(GO:0072112) glomerular epithelial cell differentiation(GO:0072311)
0.0 1.4 GO:0000045 autophagosome assembly(GO:0000045)
0.0 0.6 GO:0034340 response to type I interferon(GO:0034340)
0.0 0.0 GO:0071707 immunoglobulin heavy chain V-D-J recombination(GO:0071707)
0.0 0.2 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.0 0.6 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 0.5 GO:0050891 multicellular organismal water homeostasis(GO:0050891)
0.0 0.2 GO:0010881 regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion(GO:0010881)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.9 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.1 0.8 GO:0042382 paraspeckles(GO:0042382)
0.1 0.4 GO:1990769 proximal neuron projection(GO:1990769)
0.1 0.4 GO:0008091 spectrin(GO:0008091)
0.1 0.7 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.1 0.4 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 1.4 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.4 GO:0045098 type III intermediate filament(GO:0045098)
0.0 0.9 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.2 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0 0.2 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0 0.1 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.0 1.3 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.0 0.5 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 0.1 GO:0097447 dendritic tree(GO:0097447)
0.0 0.2 GO:0001533 cornified envelope(GO:0001533)
0.0 0.5 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 0.5 GO:0034706 sodium channel complex(GO:0034706)
0.0 0.1 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.1 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.0 0.9 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 1.4 GO:0005776 autophagosome(GO:0005776)
0.0 0.2 GO:0005686 U2 snRNP(GO:0005686)
0.0 0.2 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.2 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.1 GO:0008250 oligosaccharyltransferase complex(GO:0008250)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0090556 apolipoprotein receptor activity(GO:0030226) apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.2 0.9 GO:0032029 myosin tail binding(GO:0032029)
0.2 0.9 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.2 0.8 GO:0032810 sterol response element binding(GO:0032810)
0.1 0.9 GO:0005000 vasopressin receptor activity(GO:0005000)
0.1 0.5 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.1 0.6 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704) IkappaB kinase activity(GO:0008384)
0.1 0.3 GO:0004145 diamine N-acetyltransferase activity(GO:0004145)
0.1 0.9 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.1 0.4 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.1 0.4 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.1 0.4 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.1 0.5 GO:0008527 taste receptor activity(GO:0008527)
0.1 0.4 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.1 0.6 GO:0050786 RAGE receptor binding(GO:0050786)
0.1 0.4 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.1 0.2 GO:0046592 polyamine oxidase activity(GO:0046592) spermine:oxygen oxidoreductase (spermidine-forming) activity(GO:0052901)
0.1 0.5 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.1 0.2 GO:0035663 Toll-like receptor 2 binding(GO:0035663)
0.1 0.7 GO:0019865 immunoglobulin binding(GO:0019865)
0.0 0.1 GO:0061711 N(6)-L-threonylcarbamoyladenine synthase(GO:0061711)
0.0 0.5 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.1 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.0 0.5 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.2 GO:0016416 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0 0.4 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.2 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.0 0.4 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.2 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.5 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.0 0.2 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.0 0.2 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 0.4 GO:0019825 oxygen binding(GO:0019825)
0.0 0.2 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.0 0.1 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.0 0.2 GO:0016661 oxidoreductase activity, acting on other nitrogenous compounds as donors(GO:0016661)
0.0 0.7 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.2 GO:0000150 recombinase activity(GO:0000150)
0.0 0.9 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.4 GO:0019215 intermediate filament binding(GO:0019215)
0.0 0.1 GO:0070698 type I activin receptor binding(GO:0070698)
0.0 0.1 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.0 0.2 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.0 0.6 GO:0043236 laminin binding(GO:0043236)
0.0 0.4 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.4 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.0 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.0 0.2 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.2 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.2 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.0 0.1 GO:0070567 cytidylyltransferase activity(GO:0070567)
0.0 0.4 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.6 GO:0004177 aminopeptidase activity(GO:0004177)
0.0 0.6 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 1.3 GO:0043130 ubiquitin binding(GO:0043130)
0.0 0.5 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.3 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.1 GO:0004579 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 2.0 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.4 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.5 PID ARF 3PATHWAY Arf1 pathway
0.0 0.3 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.1 0.5 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.1 0.5 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.1 1.2 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.9 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.6 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 0.6 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.5 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.2 REACTOME ACYL CHAIN REMODELLING OF PE Genes involved in Acyl chain remodelling of PE
0.0 0.8 REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION Genes involved in RORA Activates Circadian Expression
0.0 0.5 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.4 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.7 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.4 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0 0.3 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.4 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.2 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.4 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism