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2D miR_HR1_12

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Results for E2f6

Z-value: 0.78

Motif logo

Transcription factors associated with E2f6

Gene Symbol Gene ID Gene Info
ENSMUSG00000057469.7 E2F transcription factor 6

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
E2f6mm10_v2_chr12_+_16810940_16810978-0.528.4e-02Click!

Activity profile of E2f6 motif

Sorted Z-values of E2f6 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr8_-_105637403 0.81 ENSMUST00000182046.1
predicted gene 5914
chr7_+_121707189 0.77 ENSMUST00000065310.2
RIKEN cDNA 1700069B07 gene
chr6_+_49822710 0.61 ENSMUST00000031843.6
neuropeptide Y
chr1_-_74885322 0.55 ENSMUST00000159232.1
ENSMUST00000068631.3
FEV (ETS oncogene family)
chr2_-_172940299 0.51 ENSMUST00000009143.7
bone morphogenetic protein 7
chr12_-_109068173 0.50 ENSMUST00000073156.7
brain-enriched guanylate kinase-associated
chr10_-_116473418 0.48 ENSMUST00000087965.4
ENSMUST00000164271.1
potassium large conductance calcium-activated channel, subfamily M, beta member 4
chr8_-_105637350 0.45 ENSMUST00000182863.1
predicted gene 5914
chr12_+_8771317 0.43 ENSMUST00000020911.7
syndecan 1
chr1_-_135375233 0.40 ENSMUST00000041240.3
shisa homolog 4 (Xenopus laevis)
chr2_-_66124994 0.39 ENSMUST00000028378.3
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 3
chr7_-_44816586 0.39 ENSMUST00000047356.8
activating transcription factor 5
chr2_+_164562579 0.37 ENSMUST00000017867.3
ENSMUST00000109344.2
ENSMUST00000109345.2
WAP four-disulfide core domain 2
chr5_+_137030275 0.37 ENSMUST00000041543.8
VGF nerve growth factor inducible
chr17_-_35516780 0.37 ENSMUST00000160885.1
ENSMUST00000159009.1
ENSMUST00000161012.1
transcription factor 19
chr3_+_90541146 0.36 ENSMUST00000107333.1
ENSMUST00000107331.1
ENSMUST00000098910.2
S100 calcium binding protein A16
chr16_+_20733104 0.34 ENSMUST00000115423.1
ENSMUST00000007171.6
chordin
chr7_+_3332918 0.33 ENSMUST00000092891.4
calcium channel, voltage-dependent, gamma subunit 7
chr2_-_84743655 0.33 ENSMUST00000181711.1
predicted gene, 19426
chr4_+_126556994 0.32 ENSMUST00000147675.1
claspin
chr2_+_31950257 0.32 ENSMUST00000001920.7
allograft inflammatory factor 1-like
chr17_+_35517100 0.31 ENSMUST00000164242.2
ENSMUST00000045956.7
coiled-coil alpha-helical rod protein 1
chr19_+_6497772 0.31 ENSMUST00000113458.1
ENSMUST00000113459.1
neurexin II
chr4_+_141242850 0.30 ENSMUST00000138096.1
ENSMUST00000006618.2
ENSMUST00000125392.1
Rho guanine nucleotide exchange factor (GEF) 19
chr7_-_81706905 0.30 ENSMUST00000026922.7
homer homolog 2 (Drosophila)
chr7_+_5057161 0.30 ENSMUST00000045543.5
coiled-coil domain containing 106
chr7_+_35802593 0.30 ENSMUST00000052454.2
RIKEN cDNA E130304I02 gene
chr10_-_128401218 0.29 ENSMUST00000042666.5
solute carrier family 39 (metal ion transporter), member 5
chr6_+_42349826 0.29 ENSMUST00000070635.6
zyxin
chr14_+_54431597 0.28 ENSMUST00000089688.4
matrix metallopeptidase 14 (membrane-inserted)
chr13_-_71963713 0.28 ENSMUST00000077337.8
Iroquois related homeobox 1 (Drosophila)
chr19_+_6418731 0.28 ENSMUST00000113462.1
ENSMUST00000077182.6
ENSMUST00000113461.1
neurexin II
chr11_+_87755567 0.28 ENSMUST00000123700.1
RIKEN cDNA A430104N18 gene
chr8_+_105348163 0.28 ENSMUST00000073149.5
solute carrier family 9 (sodium/hydrogen exchanger), member 5
chr1_+_74771886 0.27 ENSMUST00000006716.6
wingless-related MMTV integration site 6
chr13_+_48662989 0.27 ENSMUST00000021813.4
BarH-like homeobox 1
chr11_-_95587691 0.27 ENSMUST00000000122.6
nerve growth factor receptor (TNFR superfamily, member 16)
chr4_-_151996113 0.27 ENSMUST00000055688.9
PHD finger protein 13
chr3_+_135826075 0.27 ENSMUST00000029810.5
solute carrier family 39 (metal ion transporter), member 8
chr17_+_47436615 0.26 ENSMUST00000037701.6
expressed sequence AI661453
chr15_+_102144362 0.26 ENSMUST00000023807.6
insulin-like growth factor binding protein 6
chr6_-_28449251 0.26 ENSMUST00000164519.2
ENSMUST00000171089.2
ENSMUST00000031718.7
paired box gene 4
chr8_-_102785093 0.26 ENSMUST00000075190.3
cadherin 11
chr19_-_58454580 0.26 ENSMUST00000129100.1
ENSMUST00000123957.1
glial cell line derived neurotrophic factor family receptor alpha 1
chr7_-_78577771 0.26 ENSMUST00000039438.7
neurotrophic tyrosine kinase, receptor, type 3
chr6_-_125313844 0.26 ENSMUST00000032489.7
lymphotoxin B receptor
chr4_+_129105532 0.25 ENSMUST00000106064.3
ENSMUST00000030575.8
ENSMUST00000030577.4
transmembrane protein 54
chr3_-_144202300 0.25 ENSMUST00000121796.1
ENSMUST00000121112.1
LIM domain only 4
chr4_-_154636831 0.25 ENSMUST00000030902.6
ENSMUST00000105637.1
ENSMUST00000070313.7
ENSMUST00000105636.1
ENSMUST00000105638.2
ENSMUST00000097759.2
ENSMUST00000124771.1
PR domain containing 16
chr4_+_129985098 0.25 ENSMUST00000106017.1
ENSMUST00000121049.1
brain-specific angiogenesis inhibitor 2
chr17_+_35841668 0.24 ENSMUST00000174124.1
mediator of DNA damage checkpoint 1
chr19_+_53529100 0.24 ENSMUST00000038287.6
dual specificity phosphatase 5
chr12_-_32953772 0.24 ENSMUST00000180391.1
ENSMUST00000181670.1
RIKEN cDNA 4933406C10 gene
chr8_+_26977336 0.24 ENSMUST00000154256.1
ENSMUST00000127097.1
zinc finger protein 703
chr12_+_79130777 0.24 ENSMUST00000021550.6
arginase type II
chr2_-_144331695 0.24 ENSMUST00000103171.3
ovo-like 2 (Drosophila)
chr19_-_10457447 0.23 ENSMUST00000171400.2
leucine rich repeat containing 10B
chr4_-_91372028 0.23 ENSMUST00000107110.1
ENSMUST00000008633.8
ENSMUST00000107118.1
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr19_+_27217357 0.23 ENSMUST00000047645.6
ENSMUST00000167487.1
very low density lipoprotein receptor
chr3_-_108226598 0.23 ENSMUST00000029486.7
ENSMUST00000156371.1
ENSMUST00000141387.1
synaptophysin-like 2
chr12_-_76709997 0.23 ENSMUST00000166101.1
spectrin beta, erythrocytic
chr2_-_144332146 0.23 ENSMUST00000037423.3
ovo-like 2 (Drosophila)
chr11_+_95010277 0.23 ENSMUST00000124735.1
sterile alpha motif domain containing 14
chr14_+_60768120 0.22 ENSMUST00000025940.6
C1q and tumor necrosis factor related protein 9
chrX_+_8271642 0.22 ENSMUST00000115590.1
solute carrier family 38, member 5
chr15_-_55906722 0.22 ENSMUST00000110200.2
syntrophin, basic 1
chr11_-_101785252 0.22 ENSMUST00000164750.1
ENSMUST00000107176.1
ENSMUST00000017868.6
ets variant gene 4 (E1A enhancer binding protein, E1AF)
chr2_+_92599671 0.21 ENSMUST00000065797.6
carbohydrate (keratan sulfate Gal-6) sulfotransferase 1
chr15_-_103366763 0.21 ENSMUST00000023128.6
integrin alpha 5 (fibronectin receptor alpha)
chr4_-_137796350 0.21 ENSMUST00000030551.4
alkaline phosphatase, liver/bone/kidney
chr11_+_78188737 0.21 ENSMUST00000108322.2
RAB34, member of RAS oncogene family
chr5_+_33721724 0.21 ENSMUST00000067150.7
ENSMUST00000169212.2
ENSMUST00000114411.2
ENSMUST00000164207.3
fibroblast growth factor receptor 3
chr4_+_152274191 0.20 ENSMUST00000105650.1
ENSMUST00000105651.1
G protein-coupled receptor 153
chr15_-_98898483 0.20 ENSMUST00000023737.4
desert hedgehog
chr5_-_138171216 0.20 ENSMUST00000147920.1
minichromosome maintenance deficient 7 (S. cerevisiae)
chr17_-_79020816 0.20 ENSMUST00000168887.1
ENSMUST00000119284.1
protein kinase D3
chr10_-_85102487 0.20 ENSMUST00000059383.6
four and a half LIM domains 4
chr18_+_60911757 0.20 ENSMUST00000040359.5
arylsulfatase i
chrX_+_100729917 0.20 ENSMUST00000019503.7
glycerophosphodiester phosphodiesterase domain containing 2
chr10_-_116473875 0.19 ENSMUST00000068233.4
potassium large conductance calcium-activated channel, subfamily M, beta member 4
chr12_-_84698769 0.19 ENSMUST00000095550.2
synapse differentiation inducing 1 like
chr7_+_118855735 0.19 ENSMUST00000098087.2
ENSMUST00000106547.1
IQ motif containing K
chr19_-_5468487 0.19 ENSMUST00000025844.4
cathepsin W
chr3_-_144205165 0.19 ENSMUST00000120539.1
LIM domain only 4
chr10_+_3366125 0.19 ENSMUST00000043374.5
protein phosphatase 1, regulatory (inhibitor) subunit 14c
chr9_-_106656081 0.19 ENSMUST00000023959.7
glutamate receptor, metabotropic 2
chr5_-_138279960 0.18 ENSMUST00000014089.7
ENSMUST00000161827.1
glypican 2 (cerebroglycan)
chr7_-_67759735 0.18 ENSMUST00000074233.4
ENSMUST00000051389.8
synemin, intermediate filament protein
chr11_+_78188806 0.18 ENSMUST00000056241.5
RAB34, member of RAS oncogene family
chr2_+_27886416 0.18 ENSMUST00000028280.7
collagen, type V, alpha 1
chr2_-_91931696 0.18 ENSMUST00000090602.5
midkine
chr7_-_31051431 0.18 ENSMUST00000073892.4
FXYD domain-containing ion transport regulator 7
chr13_-_73847603 0.18 ENSMUST00000118096.1
ENSMUST00000022051.7
naked cuticle 2 homolog (Drosophila)
chr9_-_71592346 0.18 ENSMUST00000093823.1
myocardial zonula adherens protein
chr8_-_113848615 0.17 ENSMUST00000093113.4
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 18
chr15_-_100729326 0.17 ENSMUST00000159715.1
ENSMUST00000052069.5
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 6
chr19_-_42431778 0.17 ENSMUST00000048630.6
cartilage acidic protein 1
chr7_-_99353104 0.17 ENSMUST00000169437.1
ENSMUST00000094154.4
serine (or cysteine) peptidase inhibitor, clade H, member 1
chr5_-_36398090 0.17 ENSMUST00000037370.7
ENSMUST00000070720.6
sortilin-related VPS10 domain containing receptor 2
chr11_+_102604370 0.17 ENSMUST00000057893.5
frizzled homolog 2 (Drosophila)
chr5_-_84417359 0.17 ENSMUST00000113401.1
Eph receptor A5
chr7_+_27653906 0.17 ENSMUST00000008088.7
tetratricopeptide repeat domain 9B
chr17_+_56040350 0.17 ENSMUST00000002914.8
chromatin assembly factor 1, subunit A (p150)
chr11_-_103101609 0.17 ENSMUST00000103077.1
phospholipase C, delta 3
chr6_+_108660616 0.17 ENSMUST00000032194.4
basic helix-loop-helix family, member e40
chr11_-_97699634 0.17 ENSMUST00000103148.1
ENSMUST00000169807.1
polycomb group ring finger 2
chr15_-_96642311 0.17 ENSMUST00000088454.5
solute carrier family 38, member 1
chr7_+_73375494 0.17 ENSMUST00000094312.5
ENSMUST00000119206.1
RGM domain family, member A
chr16_+_65815508 0.16 ENSMUST00000168064.1
vestigial like 3 (Drosophila)
chr5_+_137350101 0.16 ENSMUST00000061244.8
Eph receptor B4
chr11_+_116918844 0.16 ENSMUST00000103027.3
mannoside acetylglucosaminyltransferase 5, isoenzyme B
chr5_+_125003440 0.16 ENSMUST00000036109.3
family with sequence similarity 101, member A
chr14_-_29721835 0.16 ENSMUST00000022567.7
calcium channel, voltage-dependent, alpha2/delta subunit 3
chr17_+_87672523 0.16 ENSMUST00000172855.1
mutS homolog 2 (E. coli)
chr10_-_62327757 0.16 ENSMUST00000139228.1
hexokinase 1
chr6_+_108660772 0.16 ENSMUST00000163617.1
basic helix-loop-helix family, member e40
chr2_+_69822370 0.16 ENSMUST00000053087.3
kelch-like 23
chr7_-_126649556 0.16 ENSMUST00000084587.1
RIKEN cDNA 2510046G10 gene
chr12_+_69168808 0.15 ENSMUST00000110621.1
leucine rich repeat protein 1
chr3_-_95739544 0.15 ENSMUST00000153026.1
ENSMUST00000123143.1
ENSMUST00000137912.1
ENSMUST00000029753.6
ENSMUST00000131376.1
ENSMUST00000117507.2
ENSMUST00000128885.1
ENSMUST00000147217.1
extracellular matrix protein 1
chrX_+_73483602 0.15 ENSMUST00000033741.8
ENSMUST00000169489.1
biglycan
chrX_-_85776606 0.15 ENSMUST00000142152.1
ENSMUST00000156390.1
ENSMUST00000113978.2
glycerol kinase
chr9_+_59589288 0.15 ENSMUST00000121266.1
ENSMUST00000118164.1
CUGBP, Elav-like family member 6
chr19_-_28967794 0.15 ENSMUST00000162110.1
RIKEN cDNA 4430402I18 gene
chr14_+_34819811 0.15 ENSMUST00000043349.5
glutamate receptor, ionotropic, delta 1
chr4_+_9844349 0.15 ENSMUST00000057613.2
growth differentiation factor 6
chr11_-_62648458 0.15 ENSMUST00000057194.8
family with sequence similarity 211, member A
chr3_+_156562141 0.15 ENSMUST00000175773.1
neuronal growth regulator 1
chr19_+_27217011 0.15 ENSMUST00000164746.1
ENSMUST00000172302.1
very low density lipoprotein receptor
chr1_-_163313661 0.14 ENSMUST00000174397.1
ENSMUST00000075805.6
ENSMUST00000027878.7
paired related homeobox 1
chr19_-_40271506 0.14 ENSMUST00000068439.6
PDZ and LIM domain 1 (elfin)
chr6_+_42350000 0.14 ENSMUST00000164375.1
zyxin
chr5_-_117319242 0.14 ENSMUST00000100834.1
predicted gene 10399
chr7_+_3390629 0.14 ENSMUST00000182222.1
calcium channel, voltage-dependent, gamma subunit 8
chr11_-_114795888 0.14 ENSMUST00000000206.3
BTB (POZ) domain containing 17
chr15_-_79505241 0.14 ENSMUST00000057801.6
potassium inwardly-rectifying channel, subfamily J, member 4
chr4_-_127330799 0.14 ENSMUST00000046532.3
gap junction protein, beta 3
chr7_+_143107252 0.14 ENSMUST00000009689.4
potassium voltage-gated channel, subfamily Q, member 1
chr1_+_120340569 0.14 ENSMUST00000037286.8
complement component 1, q subcomponent-like 2
chr16_-_4003750 0.14 ENSMUST00000171658.1
ENSMUST00000171762.1
SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae)
chr12_+_24708241 0.14 ENSMUST00000020980.5
ribonucleotide reductase M2
chr4_+_100776664 0.14 ENSMUST00000030257.8
ENSMUST00000097955.2
cache domain containing 1
chr2_+_174760619 0.14 ENSMUST00000029030.2
endothelin 3
chr9_+_119402444 0.14 ENSMUST00000035093.8
ENSMUST00000165044.1
activin receptor IIB
chr11_-_116412965 0.14 ENSMUST00000100202.3
ENSMUST00000106398.2
ring finger protein 157
chr7_-_70360593 0.14 ENSMUST00000032768.7
nuclear receptor subfamily 2, group F, member 2
chrX_+_150594420 0.14 ENSMUST00000112713.2
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr5_+_76657673 0.14 ENSMUST00000128112.1
RIKEN cDNA C530008M17 gene
chr5_+_115845229 0.14 ENSMUST00000137952.1
ENSMUST00000148245.1
citron
chr3_-_89418287 0.13 ENSMUST00000029679.3
CDC28 protein kinase 1b
chr14_+_55540266 0.13 ENSMUST00000048781.3
phosphoenolpyruvate carboxykinase 2 (mitochondrial)
chr11_+_4236411 0.13 ENSMUST00000075221.2
oncostatin M
chr11_+_70054334 0.13 ENSMUST00000018699.6
ENSMUST00000108585.2
asialoglycoprotein receptor 1
chr2_-_168281120 0.13 ENSMUST00000109191.1
potassium voltage-gated channel, subfamily G, member 1
chr8_-_84104773 0.13 ENSMUST00000041367.7
DDB1 and CUL4 associated factor 15
chr17_+_29490812 0.13 ENSMUST00000024811.6
proviral integration site 1
chr4_+_43046014 0.13 ENSMUST00000180426.1
predicted gene, 26881
chr11_-_101095367 0.13 ENSMUST00000019447.8
proteasome (prosome, macropain) 26S subunit, ATPase 3, interacting protein
chr3_+_97032416 0.13 ENSMUST00000132256.1
ENSMUST00000072600.6
gap junction protein, alpha 5
chr6_-_72235559 0.13 ENSMUST00000042646.7
atonal homolog 8 (Drosophila)
chr15_-_76521902 0.13 ENSMUST00000164703.1
ENSMUST00000096365.3
scratch homolog 1, zinc finger protein (Drosophila)
chr3_+_105452326 0.13 ENSMUST00000098761.3
potassium voltage-gated channel, Shal-related family, member 3
chr11_-_28584260 0.13 ENSMUST00000093253.3
ENSMUST00000109502.2
ENSMUST00000042534.8
coiled-coil domain containing 85A
chr2_-_36104060 0.13 ENSMUST00000112961.3
ENSMUST00000112966.3
LIM homeobox protein 6
chr1_+_131827977 0.13 ENSMUST00000086559.6
solute carrier family 41, member 1
chr11_+_7063423 0.13 ENSMUST00000020706.4
adenylate cyclase 1
chr15_+_78842632 0.13 ENSMUST00000059619.1
CDC42 effector protein (Rho GTPase binding) 1
chr4_-_151861762 0.13 ENSMUST00000097774.2
calmodulin binding transcription activator 1
chr12_+_95692212 0.13 ENSMUST00000057324.3
fibronectin leucine rich transmembrane protein 2
chr9_-_62026788 0.13 ENSMUST00000034817.4
progestin and adipoQ receptor family member V
chr18_+_75820174 0.13 ENSMUST00000058997.7
zinc finger and BTB domain containing 7C
chr1_-_173367638 0.13 ENSMUST00000005470.4
ENSMUST00000111220.1
cell adhesion molecule 3
chr5_+_137288273 0.13 ENSMUST00000024099.4
ENSMUST00000085934.3
acetylcholinesterase
chr18_-_78206408 0.12 ENSMUST00000163367.1
solute carrier family 14 (urea transporter), member 2
chr7_+_30231884 0.12 ENSMUST00000019882.9
polymerase (RNA) II (DNA directed) polypeptide I
chr6_-_42324640 0.12 ENSMUST00000031891.8
ENSMUST00000143278.1
family with sequence similarity 131, member B
chr11_-_66525964 0.12 ENSMUST00000066679.6
shisa homolog 6 (Xenopus laevis)
chr15_-_85581809 0.12 ENSMUST00000023015.7
wingless-related MMTV integration site 7B
chr7_-_38107490 0.12 ENSMUST00000108023.3
cyclin E1
chr10_-_62651194 0.12 ENSMUST00000020270.4
DEAD (Asp-Glu-Ala-Asp) box polypeptide 50
chr5_-_108549934 0.12 ENSMUST00000129040.1
ENSMUST00000046892.9
complexin 1
chr1_-_171287916 0.12 ENSMUST00000111305.1
ubiquitin specific peptidase 21
chr15_+_55557399 0.12 ENSMUST00000022998.7
Mdm2, transformed 3T3 cell double minute p53 binding protein
chr11_-_33147400 0.12 ENSMUST00000020507.7
fibroblast growth factor 18
chr1_+_92831614 0.12 ENSMUST00000045970.6
glypican 1
chr2_-_5714490 0.12 ENSMUST00000044009.7
calcium/calmodulin-dependent protein kinase ID
chr5_+_117841839 0.12 ENSMUST00000142742.2
nitric oxide synthase 1, neuronal
chr11_+_70540260 0.12 ENSMUST00000018429.5
ENSMUST00000108557.3
ENSMUST00000108556.1
phospholipase D2
chr9_-_37552904 0.12 ENSMUST00000065668.5
neurogranin
chr7_-_44306903 0.12 ENSMUST00000004587.9
C-type lectin domain family 11, member a
chr9_-_64022043 0.12 ENSMUST00000041029.5
SMAD family member 6
chr9_-_64022027 0.12 ENSMUST00000179458.1
SMAD family member 6
chr12_+_8771405 0.12 ENSMUST00000171158.1
syndecan 1
chr11_+_69326252 0.12 ENSMUST00000018614.2
potassium voltage-gated channel, shaker-related subfamily, beta member 3
chr3_+_127633134 0.12 ENSMUST00000029587.7
neurogenin 2
chr5_+_30588078 0.12 ENSMUST00000066295.2
potassium channel, subfamily K, member 3
chr1_-_71653162 0.12 ENSMUST00000055226.6
fibronectin 1
chr11_+_43528759 0.12 ENSMUST00000050574.6
cyclin J-like
chr17_+_24752980 0.12 ENSMUST00000044922.6
heparan sulfate (glucosamine) 3-O-sulfotransferase 6
chr13_-_105054895 0.12 ENSMUST00000063551.5
regulator of G-protein signalling 7 binding protein

Network of associatons between targets according to the STRING database.

First level regulatory network of E2f6

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:1900104 hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.1 0.6 GO:1903553 positive regulation of extracellular exosome assembly(GO:1903553)
0.1 0.4 GO:0072272 proximal/distal pattern formation involved in metanephric nephron development(GO:0072272)
0.1 0.3 GO:0034224 cellular response to zinc ion starvation(GO:0034224)
0.1 0.3 GO:0001193 maintenance of transcriptional fidelity during DNA-templated transcription elongation(GO:0001192) maintenance of transcriptional fidelity during DNA-templated transcription elongation from RNA polymerase II promoter(GO:0001193)
0.1 0.8 GO:0051611 regulation of serotonin uptake(GO:0051611)
0.1 0.3 GO:0016539 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908)
0.1 0.4 GO:0034436 glycoprotein transport(GO:0034436)
0.1 0.1 GO:0060849 regulation of transcription involved in lymphatic endothelial cell fate commitment(GO:0060849)
0.1 0.3 GO:2000523 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.1 0.7 GO:0005513 detection of calcium ion(GO:0005513)
0.1 0.4 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.1 0.2 GO:0030827 negative regulation of cGMP metabolic process(GO:0030824) negative regulation of cGMP biosynthetic process(GO:0030827) negative regulation of guanylate cyclase activity(GO:0031283)
0.1 0.3 GO:1905169 protein localization to phagocytic vesicle(GO:1905161) regulation of protein localization to phagocytic vesicle(GO:1905169) positive regulation of protein localization to phagocytic vesicle(GO:1905171)
0.1 0.2 GO:0043091 L-arginine import(GO:0043091) arginine import(GO:0090467)
0.1 0.2 GO:0098795 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.1 0.3 GO:0021914 negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
0.1 0.1 GO:1904008 response to monosodium glutamate(GO:1904008) cellular response to monosodium glutamate(GO:1904009)
0.1 0.2 GO:0007161 calcium-independent cell-matrix adhesion(GO:0007161)
0.1 0.2 GO:0045004 DNA replication proofreading(GO:0045004)
0.1 0.3 GO:0051902 negative regulation of mitochondrial depolarization(GO:0051902)
0.1 0.3 GO:0048298 positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.1 0.3 GO:0030421 defecation(GO:0030421)
0.1 0.4 GO:0060214 endocardium formation(GO:0060214)
0.1 0.2 GO:1904849 positive regulation of cell chemotaxis to fibroblast growth factor(GO:1904849) positive regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000546)
0.0 0.2 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.0 0.2 GO:0086053 AV node cell to bundle of His cell communication by electrical coupling(GO:0086053)
0.0 0.1 GO:1904431 positive regulation of t-circle formation(GO:1904431)
0.0 0.2 GO:0031443 fast-twitch skeletal muscle fiber contraction(GO:0031443)
0.0 0.2 GO:1905167 positive regulation of lysosomal protein catabolic process(GO:1905167)
0.0 0.5 GO:0021527 spinal cord association neuron differentiation(GO:0021527)
0.0 0.3 GO:0010961 cellular magnesium ion homeostasis(GO:0010961)
0.0 0.2 GO:1904451 regulation of hydrogen:potassium-exchanging ATPase activity(GO:1904451) positive regulation of hydrogen:potassium-exchanging ATPase activity(GO:1904453)
0.0 0.2 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.0 0.1 GO:0048691 positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691)
0.0 0.1 GO:0071918 urea transmembrane transport(GO:0071918)
0.0 0.1 GO:0072197 ureter morphogenesis(GO:0072197)
0.0 0.1 GO:0061642 chemoattraction of axon(GO:0061642)
0.0 0.1 GO:0061144 alveolar secondary septum development(GO:0061144)
0.0 0.2 GO:0060762 regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.0 0.1 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.0 0.1 GO:0070100 negative regulation of chemokine-mediated signaling pathway(GO:0070100)
0.0 0.4 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.0 0.1 GO:0030210 heparin biosynthetic process(GO:0030210)
0.0 0.1 GO:1900020 regulation of protein kinase C activity(GO:1900019) positive regulation of protein kinase C activity(GO:1900020)
0.0 0.2 GO:2000138 positive regulation of cell proliferation involved in heart morphogenesis(GO:2000138)
0.0 0.1 GO:1904976 response to bleomycin(GO:1904975) cellular response to bleomycin(GO:1904976)
0.0 0.1 GO:0033563 dorsal/ventral axon guidance(GO:0033563)
0.0 0.1 GO:1901675 negative regulation of histone H3-K27 acetylation(GO:1901675)
0.0 0.1 GO:0099547 regulation of translation at synapse, modulating synaptic transmission(GO:0099547) regulation of translation at postsynapse, modulating synaptic transmission(GO:0099578) positive regulation of intracellular transport of viral material(GO:1901254)
0.0 0.1 GO:0015766 disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.0 0.3 GO:0060684 epithelial-mesenchymal cell signaling(GO:0060684)
0.0 0.0 GO:0070368 positive regulation of hepatocyte differentiation(GO:0070368)
0.0 0.2 GO:0007223 Wnt signaling pathway, calcium modulating pathway(GO:0007223)
0.0 0.2 GO:0003433 chondrocyte development involved in endochondral bone morphogenesis(GO:0003433)
0.0 0.2 GO:0006868 glutamine transport(GO:0006868)
0.0 0.1 GO:0007066 female meiosis sister chromatid cohesion(GO:0007066)
0.0 0.2 GO:0051012 microtubule sliding(GO:0051012)
0.0 0.2 GO:0021891 olfactory bulb interneuron development(GO:0021891)
0.0 0.1 GO:0003032 detection of oxygen(GO:0003032)
0.0 0.1 GO:2000852 corticosterone secretion(GO:0035934) regulation of corticosterone secretion(GO:2000852)
0.0 0.2 GO:0071894 histone H2B conserved C-terminal lysine ubiquitination(GO:0071894)
0.0 0.2 GO:0021853 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.0 0.2 GO:0021569 rhombomere 3 development(GO:0021569)
0.0 0.1 GO:0051582 positive regulation of neurotransmitter uptake(GO:0051582) positive regulation of dopamine uptake involved in synaptic transmission(GO:0051586) positive regulation of catecholamine uptake involved in synaptic transmission(GO:0051944)
0.0 0.0 GO:0010512 negative regulation of phosphatidylinositol biosynthetic process(GO:0010512)
0.0 0.6 GO:0042297 vocal learning(GO:0042297) imitative learning(GO:0098596)
0.0 0.1 GO:1901740 negative regulation of myoblast fusion(GO:1901740)
0.0 0.1 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.0 0.2 GO:0089700 protein kinase D signaling(GO:0089700)
0.0 0.1 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.0 0.1 GO:0038095 positive regulation of mast cell cytokine production(GO:0032765) Fc-epsilon receptor signaling pathway(GO:0038095) vestibular reflex(GO:0060005)
0.0 0.1 GO:0030997 regulation of centriole-centriole cohesion(GO:0030997)
0.0 0.1 GO:0051309 female meiosis chromosome separation(GO:0051309)
0.0 0.0 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.0 0.1 GO:0032696 negative regulation of interleukin-13 production(GO:0032696)
0.0 0.3 GO:0021957 corticospinal tract morphogenesis(GO:0021957)
0.0 0.3 GO:1900121 negative regulation of receptor binding(GO:1900121)
0.0 0.1 GO:0008291 acetylcholine metabolic process(GO:0008291) acetate ester metabolic process(GO:1900619)
0.0 0.4 GO:0043084 penile erection(GO:0043084)
0.0 0.0 GO:1904580 regulation of intracellular mRNA localization(GO:1904580)
0.0 0.3 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.2 GO:0072017 distal tubule development(GO:0072017)
0.0 0.2 GO:0090527 actin filament reorganization(GO:0090527)
0.0 0.4 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.0 0.1 GO:0035928 rRNA import into mitochondrion(GO:0035928)
0.0 0.3 GO:0034501 protein localization to kinetochore(GO:0034501)
0.0 0.0 GO:1902630 regulation of membrane hyperpolarization(GO:1902630)
0.0 0.1 GO:0042536 negative regulation of tumor necrosis factor biosynthetic process(GO:0042536)
0.0 0.1 GO:0060454 positive regulation of gastric acid secretion(GO:0060454)
0.0 0.1 GO:0010615 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244)
0.0 0.3 GO:0032793 positive regulation of CREB transcription factor activity(GO:0032793)
0.0 0.0 GO:0021759 globus pallidus development(GO:0021759)
0.0 0.1 GO:1990839 response to endothelin(GO:1990839)
0.0 0.1 GO:0006116 NADH oxidation(GO:0006116)
0.0 0.5 GO:0032098 regulation of appetite(GO:0032098)
0.0 0.1 GO:0031117 positive regulation of microtubule depolymerization(GO:0031117)
0.0 0.1 GO:2001025 positive regulation of response to drug(GO:2001025)
0.0 0.1 GO:0038163 thrombopoietin-mediated signaling pathway(GO:0038163)
0.0 0.1 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.0 0.1 GO:0072368 regulation of lipid transport by negative regulation of transcription from RNA polymerase II promoter(GO:0072368)
0.0 0.0 GO:0098597 observational learning(GO:0098597)
0.0 0.4 GO:0071392 cellular response to estradiol stimulus(GO:0071392)
0.0 0.3 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.0 0.1 GO:0002924 negative regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002924)
0.0 0.2 GO:0015691 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.0 0.1 GO:1901536 regulation of DNA demethylation(GO:1901535) negative regulation of DNA demethylation(GO:1901536)
0.0 0.2 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
0.0 0.2 GO:0072656 maintenance of protein location in mitochondrion(GO:0072656)
0.0 0.1 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.0 0.1 GO:0015671 oxygen transport(GO:0015671)
0.0 0.1 GO:0032877 positive regulation of DNA endoreduplication(GO:0032877)
0.0 0.2 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.3 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.2 GO:0006012 galactose metabolic process(GO:0006012)
0.0 0.1 GO:1902608 negative regulation of inositol phosphate biosynthetic process(GO:0010920) regulation of large conductance calcium-activated potassium channel activity(GO:1902606) positive regulation of large conductance calcium-activated potassium channel activity(GO:1902608)
0.0 0.1 GO:0023016 signal transduction by trans-phosphorylation(GO:0023016)
0.0 0.3 GO:0051895 negative regulation of focal adhesion assembly(GO:0051895)
0.0 0.1 GO:0002946 tRNA C5-cytosine methylation(GO:0002946)
0.0 0.2 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.0 0.2 GO:2000344 positive regulation of acrosome reaction(GO:2000344)
0.0 0.3 GO:0035584 calcium-mediated signaling using intracellular calcium source(GO:0035584)
0.0 0.1 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.0 0.3 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.0 0.1 GO:0006566 threonine metabolic process(GO:0006566)
0.0 0.1 GO:0098886 modification of dendritic spine(GO:0098886)
0.0 0.1 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.0 0.1 GO:0071694 protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694)
0.0 0.1 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.0 0.0 GO:1902728 positive regulation of skeletal muscle satellite cell proliferation(GO:1902724) positive regulation of growth factor dependent skeletal muscle satellite cell proliferation(GO:1902728)
0.0 0.1 GO:0008050 female courtship behavior(GO:0008050)
0.0 0.1 GO:0048664 neuron fate determination(GO:0048664)
0.0 0.2 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.1 GO:1990504 dense core granule exocytosis(GO:1990504)
0.0 0.1 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.0 0.1 GO:0060836 lymphatic endothelial cell differentiation(GO:0060836)
0.0 0.1 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.0 GO:0007521 muscle cell fate determination(GO:0007521)
0.0 0.1 GO:0070447 positive regulation of oligodendrocyte progenitor proliferation(GO:0070447) ferrous iron import(GO:0070627) ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
0.0 0.1 GO:0070086 ubiquitin-dependent endocytosis(GO:0070086)
0.0 0.1 GO:0032264 purine nucleotide salvage(GO:0032261) IMP salvage(GO:0032264)
0.0 0.4 GO:0044342 type B pancreatic cell proliferation(GO:0044342)
0.0 0.1 GO:0046368 GDP-L-fucose metabolic process(GO:0046368)
0.0 0.1 GO:0048715 negative regulation of oligodendrocyte differentiation(GO:0048715)
0.0 0.1 GO:0070417 cellular response to cold(GO:0070417)
0.0 0.0 GO:0072194 ureter smooth muscle development(GO:0072191) ureter smooth muscle cell differentiation(GO:0072193) kidney smooth muscle tissue development(GO:0072194)
0.0 0.1 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.1 GO:0033567 DNA replication, Okazaki fragment processing(GO:0033567)
0.0 0.2 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.0 0.2 GO:0090331 negative regulation of platelet aggregation(GO:0090331)
0.0 0.1 GO:0035166 post-embryonic hemopoiesis(GO:0035166)
0.0 0.2 GO:0015816 glycine transport(GO:0015816)
0.0 0.1 GO:0097490 trigeminal nerve morphogenesis(GO:0021636) trigeminal nerve structural organization(GO:0021637) trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486) sympathetic neuron projection extension(GO:0097490) sympathetic neuron projection guidance(GO:0097491) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
0.0 0.2 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.0 0.2 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.1 GO:0034214 protein hexamerization(GO:0034214)
0.0 0.1 GO:1904721 regulation of mRNA cleavage(GO:0031437) negative regulation of mRNA cleavage(GO:0031438) regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904720) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
0.0 0.1 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.0 GO:0019046 release from viral latency(GO:0019046)
0.0 0.1 GO:2001245 regulation of phosphatidylcholine biosynthetic process(GO:2001245)
0.0 0.1 GO:0006014 D-ribose metabolic process(GO:0006014)
0.0 0.1 GO:0007620 insemination(GO:0007320) copulation(GO:0007620)
0.0 0.1 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.0 0.2 GO:0099625 ventricular cardiac muscle cell membrane repolarization(GO:0099625)
0.0 0.1 GO:0071699 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.0 0.1 GO:1902416 positive regulation of mRNA binding(GO:1902416)
0.0 0.4 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.2 GO:1902259 regulation of delayed rectifier potassium channel activity(GO:1902259)
0.0 0.1 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
0.0 0.1 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.0 0.0 GO:0036292 DNA rewinding(GO:0036292)
0.0 0.2 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.0 0.2 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.0 0.3 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.0 0.1 GO:0090308 regulation of methylation-dependent chromatin silencing(GO:0090308)
0.0 0.1 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.0 0.1 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.0 0.2 GO:1900745 positive regulation of p38MAPK cascade(GO:1900745)
0.0 0.0 GO:0010958 regulation of amino acid import(GO:0010958)
0.0 0.1 GO:0046543 development of secondary female sexual characteristics(GO:0046543)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0033186 CAF-1 complex(GO:0033186)
0.1 0.2 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.2 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.0 0.1 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.0 0.2 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.0 0.2 GO:1990794 lateral part of cell(GO:0097574) basolateral part of cell(GO:1990794) rod bipolar cell terminal bouton(GO:1990795)
0.0 0.2 GO:0000818 nuclear MIS12/MIND complex(GO:0000818)
0.0 0.2 GO:0005784 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0 0.3 GO:0044354 pinosome(GO:0044352) macropinosome(GO:0044354)
0.0 0.2 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.0 0.1 GO:0000802 transverse filament(GO:0000802)
0.0 0.4 GO:0044327 dendritic spine head(GO:0044327)
0.0 0.3 GO:0001739 sex chromatin(GO:0001739)
0.0 0.3 GO:0036454 insulin-like growth factor binding protein complex(GO:0016942) growth factor complex(GO:0036454)
0.0 0.1 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.0 0.2 GO:0060053 neurofilament cytoskeleton(GO:0060053)
0.0 0.1 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.0 0.1 GO:0098536 deuterosome(GO:0098536)
0.0 0.1 GO:0005663 DNA replication factor C complex(GO:0005663)
0.0 0.1 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.0 0.1 GO:0097444 spine apparatus(GO:0097444)
0.0 0.1 GO:0001740 Barr body(GO:0001740)
0.0 0.2 GO:0032300 mismatch repair complex(GO:0032300)
0.0 0.3 GO:0005922 connexon complex(GO:0005922)
0.0 0.2 GO:0042555 MCM complex(GO:0042555)
0.0 0.4 GO:0034361 very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.0 0.1 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.0 0.0 GO:0098855 HCN channel complex(GO:0098855)
0.0 0.3 GO:0032426 stereocilium tip(GO:0032426)
0.0 0.1 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.0 0.1 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.1 GO:0000801 central element(GO:0000801)
0.0 0.1 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.1 GO:0031595 nuclear proteasome complex(GO:0031595)
0.0 0.3 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.1 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.0 GO:0032585 multivesicular body membrane(GO:0032585)
0.0 0.1 GO:0045298 tubulin complex(GO:0045298)
0.0 0.6 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.1 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 0.1 GO:0005827 polar microtubule(GO:0005827)
0.0 0.1 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 1.2 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 0.1 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.0 GO:0070939 Dsl1p complex(GO:0070939) RZZ complex(GO:1990423)
0.0 0.2 GO:0065010 extracellular membrane-bounded organelle(GO:0065010)
0.0 0.1 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.2 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.0 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.0 0.0 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
0.0 0.1 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0034437 very-low-density lipoprotein particle binding(GO:0034189) glycoprotein transporter activity(GO:0034437)
0.1 0.2 GO:0030617 transforming growth factor beta receptor, inhibitory cytoplasmic mediator activity(GO:0030617)
0.1 0.4 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.1 0.3 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.1 0.2 GO:0016964 alpha-2 macroglobulin receptor activity(GO:0016964)
0.1 0.2 GO:0032137 guanine/thymine mispair binding(GO:0032137) single guanine insertion binding(GO:0032142)
0.1 0.2 GO:0048408 epidermal growth factor binding(GO:0048408)
0.1 0.3 GO:0019828 aspartic-type endopeptidase inhibitor activity(GO:0019828)
0.0 0.2 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.0 0.2 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.0 0.2 GO:0086077 gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling(GO:0086077)
0.0 0.1 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.0 0.2 GO:0031708 endothelin B receptor binding(GO:0031708)
0.0 0.2 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.0 1.1 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.2 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0 0.5 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.1 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.0 0.1 GO:0070052 collagen V binding(GO:0070052)
0.0 0.3 GO:0045545 syndecan binding(GO:0045545)
0.0 0.3 GO:0043426 MRF binding(GO:0043426)
0.0 0.2 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.1 GO:0008506 sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.0 0.2 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 0.8 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.1 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.0 0.2 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.0 0.3 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.0 0.2 GO:0017108 5'-flap endonuclease activity(GO:0017108)
0.0 0.2 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 0.1 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
0.0 0.3 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0 0.2 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 0.1 GO:0004104 cholinesterase activity(GO:0004104)
0.0 0.1 GO:1902379 chemoattractant activity involved in axon guidance(GO:1902379)
0.0 0.3 GO:0005003 ephrin receptor activity(GO:0005003)
0.0 0.3 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.0 0.1 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.0 0.2 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.1 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.0 0.2 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.0 0.2 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.1 GO:0030977 taurine binding(GO:0030977)
0.0 0.2 GO:0034056 estrogen response element binding(GO:0034056)
0.0 0.5 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.2 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.2 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.0 0.2 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.1 GO:0042015 interleukin-20 binding(GO:0042015)
0.0 0.1 GO:0005113 patched binding(GO:0005113)
0.0 0.1 GO:1990188 euchromatin binding(GO:1990188)
0.0 0.2 GO:0030375 thyroid hormone receptor coactivator activity(GO:0030375)
0.0 0.2 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.1 GO:0001034 polymerase III regulatory region sequence-specific DNA binding(GO:0000992) RNA polymerase III type 1 promoter sequence-specific DNA binding(GO:0001002) RNA polymerase III type 2 promoter sequence-specific DNA binding(GO:0001003) RNA polymerase III transcription factor activity, sequence-specific DNA binding(GO:0001034)
0.0 0.1 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.3 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.1 GO:0001716 L-amino-acid oxidase activity(GO:0001716)
0.0 0.1 GO:0043404 corticotrophin-releasing factor receptor activity(GO:0015056) corticotropin-releasing hormone receptor activity(GO:0043404)
0.0 0.3 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 0.1 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 0.1 GO:0031849 olfactory receptor binding(GO:0031849)
0.0 0.2 GO:0019158 fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0 0.1 GO:0045340 mercury ion binding(GO:0045340)
0.0 0.1 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.0 0.3 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.9 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.1 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
0.0 0.1 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.1 GO:0005344 oxygen transporter activity(GO:0005344)
0.0 0.3 GO:1990459 transferrin receptor binding(GO:1990459)
0.0 0.2 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 0.1 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.0 0.6 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.1 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.2 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 0.1 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.0 0.2 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.1 GO:0004844 uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.0 0.0 GO:0070996 type 1 melanocortin receptor binding(GO:0070996)
0.0 0.1 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.0 GO:0038025 reelin receptor activity(GO:0038025)
0.0 0.1 GO:0004331 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.0 0.1 GO:0070087 chromo shadow domain binding(GO:0070087)
0.0 0.1 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.1 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.1 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.0 0.5 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 0.1 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.1 GO:0034711 inhibin binding(GO:0034711)
0.0 0.0 GO:0002153 steroid receptor RNA activator RNA binding(GO:0002153)
0.0 0.0 GO:0043237 laminin-1 binding(GO:0043237)
0.0 0.0 GO:0048256 flap endonuclease activity(GO:0048256)
0.0 0.2 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.0 0.3 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.1 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.0 GO:0008199 ferric iron binding(GO:0008199)
0.0 0.0 GO:0047288 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836) monosialoganglioside sialyltransferase activity(GO:0047288)
0.0 0.2 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.2 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.2 GO:0017166 vinculin binding(GO:0017166)
0.0 0.1 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.0 0.3 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.2 GO:0005326 neurotransmitter transporter activity(GO:0005326)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.7 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.1 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 1.0 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.4 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.6 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.8 PID ATR PATHWAY ATR signaling pathway
0.0 0.3 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.7 PID BMP PATHWAY BMP receptor signaling
0.0 0.1 ST STAT3 PATHWAY STAT3 Pathway
0.0 0.3 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.2 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.7 PID ILK PATHWAY Integrin-linked kinase signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 0.1 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.0 0.6 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.3 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.0 0.5 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 0.8 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.2 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.3 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.3 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.0 0.3 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.1 REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.0 0.2 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.2 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 0.0 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0 0.4 REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX Genes involved in Activation of the pre-replicative complex
0.0 0.7 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.1 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.2 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.5 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.2 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.3 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.1 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.2 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.1 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.1 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 0.1 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 0.5 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.1 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 0.1 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR