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2D miR_HR1_12

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Results for Nfe2l1_Mafg

Z-value: 0.96

Motif logo

Transcription factors associated with Nfe2l1_Mafg

Gene Symbol Gene ID Gene Info
ENSMUSG00000038615.11 nuclear factor, erythroid derived 2,-like 1
ENSMUSG00000051510.7 v-maf musculoaponeurotic fibrosarcoma oncogene family, protein G (avian)
ENSMUSG00000053906.4 v-maf musculoaponeurotic fibrosarcoma oncogene family, protein G (avian)

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Mafgmm10_v2_chr11_-_120630126_120630160-0.763.9e-03Click!
Nfe2l1mm10_v2_chr11_-_96829904_96829955-0.127.0e-01Click!

Activity profile of Nfe2l1_Mafg motif

Sorted Z-values of Nfe2l1_Mafg motif

Promoter Log-likelihood Transcript Gene Gene Info
chr5_+_35056813 2.77 ENSMUST00000101298.2
ENSMUST00000114270.1
ENSMUST00000133381.1
docking protein 7
chr5_+_35057059 1.50 ENSMUST00000050709.3
docking protein 7
chr5_+_30913398 1.26 ENSMUST00000031055.5
elastin microfibril interfacer 1
chr9_+_35211155 1.25 ENSMUST00000034541.5
signal recognition particle receptor ('docking protein')
chr11_+_102145530 1.16 ENSMUST00000055409.5
N-acetylglutamate synthase
chr13_+_111867931 1.12 ENSMUST00000128198.1
predicted gene 15326
chr7_+_127841752 1.11 ENSMUST00000033075.7
syntaxin 4A (placental)
chr9_-_66834648 1.08 ENSMUST00000057261.8
ENSMUST00000169282.1
anterior pharynx defective 1c homolog (C. elegans)
chr11_+_98664341 1.06 ENSMUST00000017348.2
gasdermin A
chr1_+_88087802 1.04 ENSMUST00000113139.1
UDP glucuronosyltransferase 1 family, polypeptide A8
chr7_-_137314394 0.96 ENSMUST00000168203.1
ENSMUST00000106118.2
ENSMUST00000169486.2
ENSMUST00000033378.5
early B cell factor 3
chr13_-_18382041 0.95 ENSMUST00000139064.2
ENSMUST00000175703.2
POU domain, class 6, transcription factor 2
chr11_-_119040905 0.88 ENSMUST00000026663.7
chromobox 8
chr5_-_124032214 0.87 ENSMUST00000040967.7
vacuolar protein sorting 37B (yeast)
chr7_+_127841817 0.85 ENSMUST00000121705.1
syntaxin 4A (placental)
chr3_+_157566868 0.84 ENSMUST00000041175.6
ENSMUST00000173533.1
prostaglandin E receptor 3 (subtype EP3)
chr11_-_109298121 0.84 ENSMUST00000020920.3
regulator of G-protein signaling 9
chr1_+_88070765 0.78 ENSMUST00000073772.4
UDP glucuronosyltransferase 1 family, polypeptide A9
chr3_-_59262825 0.77 ENSMUST00000050360.7
purinergic receptor P2Y, G-protein coupled 12
chr4_-_114908892 0.71 ENSMUST00000068654.3
forkhead box D2
chr2_-_30903255 0.68 ENSMUST00000102852.3
prostaglandin E synthase
chr16_-_88563166 0.68 ENSMUST00000049697.4
claudin 8
chr6_-_72361396 0.66 ENSMUST00000130064.1
ring finger protein 181
chr3_-_89402650 0.66 ENSMUST00000168325.1
ENSMUST00000057431.5
lens epithelial protein
chr17_+_6673610 0.66 ENSMUST00000097430.2
synaptotagmin-like 3
chr5_+_33104219 0.65 ENSMUST00000011178.2
solute carrier family 5 (sodium/glucose cotransporter), member 1
chr11_+_95010277 0.64 ENSMUST00000124735.1
sterile alpha motif domain containing 14
chr13_-_38635036 0.64 ENSMUST00000035899.6
biogenesis of organelles complex-1, subunit 5, muted
chr11_-_109298066 0.63 ENSMUST00000106706.1
regulator of G-protein signaling 9
chr17_+_93199348 0.62 ENSMUST00000064775.6
adenylate cyclase activating polypeptide 1
chr8_-_35826435 0.62 ENSMUST00000060128.5
claudin 23
chr15_+_12321472 0.57 ENSMUST00000059680.5
golgi phosphoprotein 3
chr5_-_135349991 0.54 ENSMUST00000044972.7
FK506 binding protein 6
chr4_-_134227359 0.54 ENSMUST00000105878.2
ENSMUST00000055892.3
ENSMUST00000169381.1
cation channel, sperm associated 4
chr9_+_59589288 0.53 ENSMUST00000121266.1
ENSMUST00000118164.1
CUGBP, Elav-like family member 6
chr15_+_16778101 0.53 ENSMUST00000026432.6
cadherin 9
chr18_+_38993126 0.52 ENSMUST00000097593.2
Rho GTPase activating protein 26
chr13_+_38151324 0.49 ENSMUST00000127906.1
desmoplakin
chr17_-_63863791 0.48 ENSMUST00000050753.3
RIKEN cDNA A930002H24 gene
chr11_-_109298090 0.48 ENSMUST00000106704.2
regulator of G-protein signaling 9
chr19_+_8741669 0.47 ENSMUST00000176314.1
ENSMUST00000073430.7
ENSMUST00000175901.1
syntaxin 5A
chr6_-_83121385 0.47 ENSMUST00000146328.1
ENSMUST00000113936.3
ENSMUST00000032111.4
WW domain binding protein 1
chr4_+_43632185 0.45 ENSMUST00000107874.2
natriuretic peptide receptor 2
chr10_+_82985473 0.44 ENSMUST00000040110.7
carbohydrate sulfotransferase 11
chr2_-_148408146 0.43 ENSMUST00000099270.3
thrombomodulin
chr5_-_123140135 0.43 ENSMUST00000160099.1
expressed sequence AI480526
chr6_+_88724667 0.43 ENSMUST00000163271.1
monoglyceride lipase
chr10_-_115362191 0.43 ENSMUST00000092170.5
transmembrane protein 19
chr11_-_103208542 0.42 ENSMUST00000021323.4
ENSMUST00000107026.2
RIKEN cDNA 1700023F06 gene
chr4_-_33248500 0.42 ENSMUST00000049357.9
proline-rich nuclear receptor coactivator 1
chr10_-_127070254 0.41 ENSMUST00000060991.4
tetraspanin 31
chr13_+_38151343 0.41 ENSMUST00000124830.1
desmoplakin
chr8_+_54077532 0.41 ENSMUST00000033919.4
vascular endothelial growth factor C
chr2_-_165884636 0.41 ENSMUST00000177633.1
ENSMUST00000018050.7
ENSMUST00000088113.4
zinc finger, MYND-type containing 8
chr8_+_85060055 0.41 ENSMUST00000095220.3
F-box and WD-40 domain protein 9
chr9_-_8004585 0.40 ENSMUST00000086580.5
ENSMUST00000065353.6
yes-associated protein 1
chr3_-_85741389 0.39 ENSMUST00000094148.4
family with sequence similarity 160, member A1
chrX_-_49788204 0.38 ENSMUST00000114893.1
immunoglobulin superfamily, member 1
chr9_-_22002599 0.38 ENSMUST00000115336.2
ENSMUST00000044926.5
coiled-coil domain containing 151
chr2_-_28699636 0.37 ENSMUST00000102877.1
RIKEN cDNA 1700026L06 gene
chr5_+_19227046 0.37 ENSMUST00000088516.3
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr3_+_90062781 0.35 ENSMUST00000029551.2
RIKEN cDNA 1700094D03 gene
chr4_+_102570065 0.35 ENSMUST00000097950.2
phosphodiesterase 4B, cAMP specific
chr19_+_38836561 0.35 ENSMUST00000037302.5
TBC1D12: TBC1 domain family, member 12
chr4_-_132884509 0.34 ENSMUST00000030698.4
syntaxin 12
chr5_+_122707546 0.34 ENSMUST00000081554.6
ENSMUST00000031429.7
ENSMUST00000139631.1
ENSMUST00000142664.1
purinergic receptor P2X, ligand-gated ion channel 4
chr10_-_109823585 0.34 ENSMUST00000161582.1
neuron navigator 3
chr10_-_53750880 0.34 ENSMUST00000020003.7
family with sequence similarity 184, member A
chr17_-_33760451 0.34 ENSMUST00000057373.7
RAB11B, member RAS oncogene family
chr4_+_131921771 0.34 ENSMUST00000094666.3
transmembrane protein 200B
chr8_+_123373778 0.34 ENSMUST00000057934.3
ENSMUST00000108840.2
transcription factor 25 (basic helix-loop-helix)
chr16_+_20694908 0.34 ENSMUST00000056518.6
family with sequence similarity 131, member A
chr12_-_84361802 0.34 ENSMUST00000021659.1
ENSMUST00000065536.2
family with sequence similarity 161, member B
chr18_-_3299537 0.33 ENSMUST00000129435.1
ENSMUST00000122958.1
cAMP responsive element modulator
chr5_-_143732273 0.33 ENSMUST00000053287.5
ubiquitin specific peptidase 42
chr11_+_78536355 0.33 ENSMUST00000128788.1
intraflagellar transport 20
chr10_-_64090265 0.32 ENSMUST00000105439.1
leucine rich repeat transmembrane neuronal 3
chr6_+_88724828 0.32 ENSMUST00000089449.2
monoglyceride lipase
chr1_+_88055377 0.32 ENSMUST00000138182.1
ENSMUST00000113142.3
UDP glycosyltransferase 1 family, polypeptide A10
chr6_-_124738714 0.32 ENSMUST00000171549.2
protein tyrosine phosphatase, non-receptor type 6
chr2_-_106002008 0.32 ENSMUST00000155811.1
DnaJ (Hsp40) homolog, subfamily C, member 24
chr17_-_34031544 0.32 ENSMUST00000025186.8
solute carrier family 39 (zinc transporter), member 7
chr4_+_43441939 0.32 ENSMUST00000060864.6
testis specific protein kinase 1
chr9_+_54538984 0.32 ENSMUST00000060242.5
ENSMUST00000118413.1
SH2 domain containing 7
chr11_+_78536393 0.31 ENSMUST00000050366.8
ENSMUST00000108275.1
intraflagellar transport 20
chr2_+_127854628 0.31 ENSMUST00000028859.1
acyl-Coenzyme A oxidase-like
chr6_+_142298419 0.31 ENSMUST00000041993.2
islet amyloid polypeptide
chr8_-_3467617 0.31 ENSMUST00000111081.3
ENSMUST00000118194.1
ENSMUST00000004686.6
peroxisomal biogenesis factor 11 gamma
chr5_-_51553896 0.31 ENSMUST00000132734.1
peroxisome proliferative activated receptor, gamma, coactivator 1 alpha
chr11_+_101087277 0.30 ENSMUST00000107302.1
ENSMUST00000107303.3
ENSMUST00000017945.8
ENSMUST00000149597.1
MAX-like protein X
chr11_-_50325599 0.30 ENSMUST00000179865.1
ENSMUST00000020637.8
calnexin
chr12_-_31950535 0.29 ENSMUST00000172314.2
high mobility group box transcription factor 1
chr3_+_88629499 0.29 ENSMUST00000175745.1
rho/rac guanine nucleotide exchange factor (GEF) 2
chr11_-_61719946 0.28 ENSMUST00000151780.1
ENSMUST00000148584.1
solute carrier family 5 (sodium/glucose cotransporter), member 10
chr5_-_66151903 0.28 ENSMUST00000167950.1
RNA binding motif protein 47
chr14_+_31641051 0.28 ENSMUST00000090147.6
biotinidase
chr17_-_34031644 0.28 ENSMUST00000171872.1
solute carrier family 39 (zinc transporter), member 7
chr18_-_3281036 0.28 ENSMUST00000049942.6
ENSMUST00000139537.1
ENSMUST00000124747.1
cAMP responsive element modulator
chr14_-_31640878 0.28 ENSMUST00000167066.1
ENSMUST00000127204.2
ENSMUST00000022437.8
2-hydroxyacyl-CoA lyase 1
chr11_+_23020464 0.28 ENSMUST00000094363.3
ENSMUST00000151877.1
family with sequence similarity 161, member A
chr6_-_52208694 0.27 ENSMUST00000062829.7
homeobox A6
chr5_+_90786100 0.27 ENSMUST00000031326.8
chemokine (C-X-C motif) ligand 3
chr5_-_139826407 0.27 ENSMUST00000182839.1
predicted gene, 26938
chr3_-_92083132 0.27 ENSMUST00000058150.6
loricrin
chr3_+_3634145 0.26 ENSMUST00000108394.1
hepatocyte nuclear factor 4, gamma
chrX_-_155216338 0.26 ENSMUST00000112551.3
spermidine/spermine N1-acetyl transferase 1
chr9_-_35210964 0.26 ENSMUST00000043805.8
ENSMUST00000142595.1
ENSMUST00000127996.1
FAD-dependent oxidoreductase domain containing 1
chr9_-_66795469 0.26 ENSMUST00000034934.8
anterior pharynx defective 1b homolog (C. elegans)
chr18_-_3299452 0.25 ENSMUST00000126578.1
cAMP responsive element modulator
chr5_+_122643878 0.25 ENSMUST00000100737.3
ENSMUST00000121489.1
ENSMUST00000031425.8
ENSMUST00000086247.5
purinergic receptor P2X, ligand-gated ion channel, 7
chr1_+_135729147 0.25 ENSMUST00000027677.7
cysteine and glycine-rich protein 1
chr6_-_129507107 0.25 ENSMUST00000183258.1
ENSMUST00000182784.1
ENSMUST00000032265.6
ENSMUST00000162815.1
oxidized low density lipoprotein (lectin-like) receptor 1
chr14_-_52279238 0.25 ENSMUST00000167116.1
ENSMUST00000100631.4
RAB2B, member RAS oncogene family
chr6_+_114131229 0.25 ENSMUST00000032451.7
solute carrier family 6 (neurotransmitter transporter, GABA), member 11
chr3_-_83049797 0.25 ENSMUST00000048246.3
fibrinogen beta chain
chr3_+_88629442 0.24 ENSMUST00000176316.1
ENSMUST00000176879.1
rho/rac guanine nucleotide exchange factor (GEF) 2
chr15_-_42676967 0.24 ENSMUST00000022921.5
angiopoietin 1
chr7_-_84679346 0.24 ENSMUST00000069537.2
ENSMUST00000178385.1
zinc finger, AN1-type domain 6
chr18_+_35771574 0.24 ENSMUST00000167406.1
ubiquitin-conjugating enzyme E2D 2A
chr2_-_112480817 0.24 ENSMUST00000099589.2
cholinergic receptor, muscarinic 5
chr14_+_29978337 0.23 ENSMUST00000016115.4
ARP8 actin-related protein 8
chr14_-_72602945 0.23 ENSMUST00000162825.1
fibronectin type III domain containing 3A
chr13_-_68999518 0.23 ENSMUST00000022013.7
adenylate cyclase 2
chr1_+_88055467 0.23 ENSMUST00000173325.1
UDP glycosyltransferase 1 family, polypeptide A10
chr5_+_90561102 0.23 ENSMUST00000094615.4
RIKEN cDNA 5830473C10 gene
chr11_-_52000432 0.23 ENSMUST00000020657.6
ubiquitin-conjugating enzyme E2B
chr2_+_18998332 0.23 ENSMUST00000028069.1
RIKEN cDNA 4930426L09 gene
chr4_+_54945038 0.22 ENSMUST00000133895.1
zinc finger protein 462
chr17_-_24169414 0.22 ENSMUST00000024932.5
ATPase, H+ transporting, lysosomal V0 subunit C
chr18_-_62179948 0.22 ENSMUST00000053640.3
adrenergic receptor, beta 2
chr2_+_11642786 0.22 ENSMUST00000028111.4
interleukin 2 receptor, alpha chain
chr8_+_94810446 0.21 ENSMUST00000034232.1
chemokine (C-C motif) ligand 17
chr17_-_55915870 0.21 ENSMUST00000074828.4
ribosomal protein L21, pseudogene 6
chr19_+_8929628 0.21 ENSMUST00000096241.4
echinoderm microtubule associated protein like 3
chr1_+_59256906 0.21 ENSMUST00000160662.1
ENSMUST00000114248.2
cyclin-dependent kinase 15
chr9_+_57940104 0.21 ENSMUST00000043059.7
sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, (semaphorin) 7A
chr10_-_79874211 0.20 ENSMUST00000167897.1
cDNA sequence BC005764
chr1_-_191183244 0.19 ENSMUST00000027941.8
activating transcription factor 3
chr13_-_38151792 0.19 ENSMUST00000078232.1
predicted gene 10129
chr8_+_94532990 0.19 ENSMUST00000048653.2
ENSMUST00000109537.1
copine II
chr13_-_55571118 0.19 ENSMUST00000021957.6
family with sequence similarity 193, member B
chr4_-_132144486 0.19 ENSMUST00000056336.1
opioid receptor, delta 1
chr15_+_54952939 0.19 ENSMUST00000181704.1
predicted gene, 26684
chr9_+_13619990 0.19 ENSMUST00000159294.1
mastermind like 2 (Drosophila)
chr10_+_80930071 0.19 ENSMUST00000015456.8
growth arrest and DNA-damage-inducible 45 beta
chrX_-_155216444 0.19 ENSMUST00000026318.8
spermidine/spermine N1-acetyl transferase 1
chr8_-_67974567 0.19 ENSMUST00000098696.3
ENSMUST00000038959.9
ENSMUST00000093469.4
pleckstrin and Sec7 domain containing 3
chr2_+_86041317 0.19 ENSMUST00000111589.1
olfactory receptor 1033
chr2_+_119742306 0.19 ENSMUST00000028758.7
inositol 1,4,5-trisphosphate 3-kinase A
chr4_-_129640691 0.19 ENSMUST00000084264.5
taxilin alpha
chr12_+_73286779 0.18 ENSMUST00000140523.1
solute carrier family 38, member 6
chr17_+_37225091 0.18 ENSMUST00000078209.3
olfactory receptor 96
chrX_+_56454871 0.18 ENSMUST00000039374.2
ENSMUST00000101553.2
DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B
chr6_+_36388055 0.18 ENSMUST00000172278.1
cholinergic receptor, muscarinic 2, cardiac
chr2_+_25272475 0.18 ENSMUST00000028341.4
anaphase promoting complex subunit 2
chrX_+_57043074 0.18 ENSMUST00000033464.3
bombesin-like receptor 3
chr6_-_140041409 0.17 ENSMUST00000032356.6
phospholipase C, zeta 1
chr5_+_107497718 0.17 ENSMUST00000112671.2
RIKEN cDNA A830010M20 gene
chr9_-_66795331 0.17 ENSMUST00000113730.2
anterior pharynx defective 1b homolog (C. elegans)
chrX_+_20688379 0.16 ENSMUST00000033380.6
cyclin-dependent kinase 16
chr12_+_38783503 0.16 ENSMUST00000159334.1
ets variant gene 1
chr12_-_84970814 0.15 ENSMUST00000165886.1
ENSMUST00000167448.1
ENSMUST00000043169.7
apoptosis resistant E3 ubiquitin protein ligase 1
chr15_-_102189032 0.15 ENSMUST00000023805.1
cysteine sulfinic acid decarboxylase
chr11_-_59964936 0.15 ENSMUST00000062405.7
RAS, dexamethasone-induced 1
chr4_+_42969945 0.15 ENSMUST00000030163.5
RIKEN cDNA 1700022I11 gene
chr11_-_53634698 0.15 ENSMUST00000020650.1
interleukin 13
chr7_-_80688852 0.15 ENSMUST00000122255.1
CREB regulated transcription coactivator 3
chr10_-_24109582 0.15 ENSMUST00000041180.5
trace amine-associated receptor 9
chr1_+_127774164 0.14 ENSMUST00000027587.8
ENSMUST00000112570.1
cyclin T2
chr7_+_118633729 0.14 ENSMUST00000057320.7
transmembrane channel-like gene family 5
chr1_-_132367879 0.14 ENSMUST00000142609.1
transmembrane and coiled-coil domains 2
chr4_-_43454600 0.14 ENSMUST00000098105.3
ENSMUST00000098104.3
ENSMUST00000030179.4
CD72 antigen
chr17_-_24169648 0.13 ENSMUST00000148541.1
ENSMUST00000098862.2
ENSMUST00000150647.1
ATPase, H+ transporting, lysosomal V0 subunit C
chr2_+_112454997 0.12 ENSMUST00000069747.5
ER membrane protein complex subunit 7
chr17_+_43952999 0.12 ENSMUST00000177857.1
regulator of calcineurin 2
chr7_+_104003259 0.12 ENSMUST00000098184.1
olfactory receptor 638
chr2_+_122298898 0.12 ENSMUST00000028656.1
dual oxidase maturation factor 2
chr19_+_56722372 0.12 ENSMUST00000038949.4
adrenergic receptor, beta 1
chr1_+_67123015 0.12 ENSMUST00000027144.7
carbamoyl-phosphate synthetase 1
chr10_-_80900749 0.11 ENSMUST00000020440.6
translocase of inner mitochondrial membrane 13
chr5_-_24842579 0.11 ENSMUST00000030787.8
Ras homolog enriched in brain
chr12_+_38783455 0.11 ENSMUST00000161980.1
ENSMUST00000160701.1
ets variant gene 1
chr11_-_66525795 0.11 ENSMUST00000123454.1
shisa homolog 6 (Xenopus laevis)
chr16_+_58727910 0.10 ENSMUST00000023426.5
ENSMUST00000162057.1
ENSMUST00000162191.1
claudin 25
chr3_+_86224665 0.10 ENSMUST00000107635.1
LPS-responsive beige-like anchor
chr17_+_35821675 0.10 ENSMUST00000003635.6
immediate early response 3
chr7_+_87803815 0.10 ENSMUST00000125009.1
ENSMUST00000155358.1
glutamate receptor, metabotropic 5
chr2_+_79707780 0.10 ENSMUST00000090760.2
ENSMUST00000040863.4
ENSMUST00000111780.2
protein phosphatase 1, regulatory (inhibitor) subunit 1C
chr4_+_33081505 0.10 ENSMUST00000147889.1
gamma-aminobutyric acid (GABA) C receptor, subunit rho 2
chr14_-_56262233 0.10 ENSMUST00000015581.4
granzyme B
chr15_+_6579841 0.10 ENSMUST00000090461.5
FYN binding protein
chr10_+_111164794 0.10 ENSMUST00000105275.1
ENSMUST00000095310.1
oxysterol binding protein-like 8
chr3_+_132634725 0.10 ENSMUST00000163241.1
predicted gene 5549
chr15_+_35296090 0.10 ENSMUST00000022952.4
odd-skipped related 2
chr7_+_30776394 0.10 ENSMUST00000041703.7
dermokine
chr11_-_58552237 0.10 ENSMUST00000073933.1
olfactory receptor 328
chr8_+_40511769 0.10 ENSMUST00000098817.2
vacuolar protein sorting 37A (yeast)
chr2_+_128967383 0.10 ENSMUST00000110320.2
ENSMUST00000110319.2
zinc finger CCCH type containing 6
chr19_-_36057340 0.10 ENSMUST00000164639.1
ENSMUST00000166074.1
ENSMUST00000099505.3
5-hydroxytryptamine (serotonin) receptor 7
chr5_+_107497762 0.09 ENSMUST00000152474.1
ENSMUST00000060553.7
RIKEN cDNA A830010M20 gene

Network of associatons between targets according to the STRING database.

First level regulatory network of Nfe2l1_Mafg

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.0 GO:0043311 positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568)
0.3 0.9 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.3 0.8 GO:1904328 gastrin-induced gastric acid secretion(GO:0001698) regulation of myofibroblast contraction(GO:1904328) myofibroblast contraction(GO:1990764) negative regulation of forebrain neuron differentiation(GO:2000978)
0.2 0.6 GO:0032474 otolith morphogenesis(GO:0032474)
0.2 0.6 GO:0090274 positive regulation of somatostatin secretion(GO:0090274)
0.2 2.4 GO:0052697 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.2 0.8 GO:1904124 microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.2 1.3 GO:0006526 arginine biosynthetic process(GO:0006526)
0.2 0.5 GO:0032917 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.1 0.7 GO:0001951 intestinal D-glucose absorption(GO:0001951)
0.1 0.9 GO:0071896 protein localization to adherens junction(GO:0071896)
0.1 0.6 GO:0090164 asymmetric Golgi ribbon formation(GO:0090164)
0.1 0.3 GO:0003099 positive regulation of the force of heart contraction by epinephrine-norepinephrine(GO:0001997) positive regulation of the force of heart contraction by chemical signal(GO:0003099)
0.1 0.8 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.1 0.4 GO:1901492 positive regulation of lymphangiogenesis(GO:1901492)
0.1 1.5 GO:0007220 Notch receptor processing(GO:0007220)
0.1 4.4 GO:0061098 positive regulation of protein tyrosine kinase activity(GO:0061098)
0.1 0.3 GO:0045054 constitutive secretory pathway(GO:0045054)
0.1 0.6 GO:0035590 purinergic nucleotide receptor signaling pathway(GO:0035590)
0.1 0.4 GO:0007207 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.1 0.4 GO:1903758 regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.1 0.2 GO:0010845 positive regulation of reciprocal meiotic recombination(GO:0010845)
0.1 0.2 GO:0030210 heparin biosynthetic process(GO:0030210)
0.1 1.1 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.1 0.3 GO:2000182 regulation of progesterone biosynthetic process(GO:2000182)
0.1 0.4 GO:0033277 abortive mitotic cell cycle(GO:0033277)
0.1 0.2 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.1 0.5 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.1 0.4 GO:0072307 metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
0.1 0.3 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.1 0.2 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.1 0.5 GO:0090166 Golgi disassembly(GO:0090166)
0.1 0.3 GO:0044375 regulation of peroxisome size(GO:0044375)
0.0 0.1 GO:0097278 negative regulation of NAD(P)H oxidase activity(GO:0033861) pancreatic stellate cell proliferation(GO:0072343) complement-dependent cytotoxicity(GO:0097278) regulation of complement-dependent cytotoxicity(GO:1903659) negative regulation of complement-dependent cytotoxicity(GO:1903660) regulation of pancreatic stellate cell proliferation(GO:2000229)
0.0 0.6 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.0 0.2 GO:1903984 positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.0 0.1 GO:0019085 early viral transcription(GO:0019085)
0.0 0.4 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 0.5 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 2.1 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.0 0.4 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.4 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.0 0.3 GO:0097646 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.0 0.1 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.0 0.1 GO:0042322 negative regulation of circadian sleep/wake cycle, REM sleep(GO:0042322) response to mineralocorticoid(GO:0051385)
0.0 0.4 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 1.3 GO:0070207 protein homotrimerization(GO:0070207)
0.0 0.9 GO:0032967 positive regulation of collagen biosynthetic process(GO:0032967)
0.0 0.5 GO:0034587 piRNA metabolic process(GO:0034587)
0.0 0.1 GO:0060854 patterning of lymph vessels(GO:0060854)
0.0 0.2 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.6 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 0.3 GO:1902004 positive regulation of beta-amyloid formation(GO:1902004)
0.0 0.3 GO:0007042 lysosomal lumen acidification(GO:0007042)
0.0 0.2 GO:0060907 positive regulation of macrophage cytokine production(GO:0060907)
0.0 0.4 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 0.1 GO:0036023 limb joint morphogenesis(GO:0036022) embryonic skeletal limb joint morphogenesis(GO:0036023)
0.0 0.1 GO:1903575 cornified envelope assembly(GO:1903575)
0.0 0.7 GO:0001516 prostaglandin biosynthetic process(GO:0001516) prostanoid biosynthetic process(GO:0046457)
0.0 0.1 GO:2000609 regulation of thyroid hormone generation(GO:2000609)
0.0 0.1 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.3 GO:0010745 negative regulation of macrophage derived foam cell differentiation(GO:0010745)
0.0 0.2 GO:0000098 sulfur amino acid catabolic process(GO:0000098)
0.0 0.2 GO:0007343 egg activation(GO:0007343)
0.0 0.2 GO:1904322 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.0 0.6 GO:0071625 vocalization behavior(GO:0071625)
0.0 0.1 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.0 0.5 GO:0048240 sperm capacitation(GO:0048240)
0.0 0.3 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.1 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.0 0.2 GO:0090129 positive regulation of synapse maturation(GO:0090129)
0.0 0.2 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.1 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.0 0.1 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.0 0.2 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.3 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 0.9 GO:0006687 glycosphingolipid metabolic process(GO:0006687)
0.0 1.0 GO:0051865 protein autoubiquitination(GO:0051865)
0.0 0.2 GO:0006968 cellular defense response(GO:0006968)
0.0 0.3 GO:0031424 keratinization(GO:0031424)
0.0 0.1 GO:2000074 regulation of type B pancreatic cell development(GO:2000074)
0.0 0.1 GO:0010040 response to iron(II) ion(GO:0010040)
0.0 0.0 GO:0021759 globus pallidus development(GO:0021759)
0.0 0.1 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.4 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.3 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
0.0 0.0 GO:0035973 aggrephagy(GO:0035973)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.0 GO:0000322 storage vacuole(GO:0000322)
0.2 1.5 GO:0070765 gamma-secretase complex(GO:0070765)
0.2 0.8 GO:1990769 proximal neuron projection(GO:1990769)
0.2 0.6 GO:1902636 kinociliary basal body(GO:1902636)
0.2 1.2 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.1 0.4 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.1 1.0 GO:0000813 ESCRT I complex(GO:0000813)
0.1 1.2 GO:0001533 cornified envelope(GO:0001533)
0.1 0.5 GO:0036128 CatSper complex(GO:0036128)
0.1 1.0 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.9 GO:0035102 PRC1 complex(GO:0035102)
0.0 1.1 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 4.5 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.3 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 0.3 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 2.0 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.2 GO:0033503 HULC complex(GO:0033503)
0.0 0.8 GO:0043196 varicosity(GO:0043196)
0.0 1.2 GO:0008305 integrin complex(GO:0008305)
0.0 0.2 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.4 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.3 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.0 0.7 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.1 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 0.4 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.3 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0 0.1 GO:0044194 cytolytic granule(GO:0044194)
0.0 0.2 GO:0031011 Ino80 complex(GO:0031011)
0.0 0.4 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.1 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.0 0.1 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.5 GO:0000795 synaptonemal complex(GO:0000795)
0.0 0.5 GO:0002102 podosome(GO:0002102)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.0 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.3 1.3 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.2 1.2 GO:0034618 arginine binding(GO:0034618)
0.2 0.7 GO:0004667 prostaglandin-D synthase activity(GO:0004667) prostaglandin-E synthase activity(GO:0050220)
0.2 1.1 GO:0005047 signal recognition particle binding(GO:0005047)
0.2 0.5 GO:0004145 diamine N-acetyltransferase activity(GO:0004145)
0.1 0.4 GO:0047756 chondroitin 4-sulfotransferase activity(GO:0047756)
0.1 0.8 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.1 0.5 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.1 0.3 GO:0051380 norepinephrine binding(GO:0051380)
0.1 0.6 GO:0002046 opsin binding(GO:0002046)
0.1 0.5 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.1 0.3 GO:0030280 structural constituent of epidermis(GO:0030280)
0.1 0.6 GO:0004931 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.1 0.4 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.1 0.9 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.1 0.2 GO:0004911 interleukin-2 receptor activity(GO:0004911)
0.1 4.2 GO:0005158 insulin receptor binding(GO:0005158)
0.1 2.4 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.1 0.8 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.1 0.2 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332) gamma-aminobutyric acid transmembrane transporter activity(GO:0015185)
0.1 0.2 GO:0004946 bombesin receptor activity(GO:0004946)
0.1 0.5 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.1 0.4 GO:0034711 inhibin binding(GO:0034711)
0.1 0.4 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 0.8 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.2 GO:0004985 opioid receptor activity(GO:0004985)
0.0 0.3 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.6 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 0.1 GO:0004087 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.0 0.6 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 0.3 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.0 0.3 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.0 0.7 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.1 GO:0001225 RNA polymerase II transcription coactivator binding(GO:0001225)
0.0 0.1 GO:0099530 PLC activating G-protein coupled glutamate receptor activity(GO:0001639) A2A adenosine receptor binding(GO:0031687) G-protein coupled receptor activity involved in regulation of postsynaptic membrane potential(GO:0099530)
0.0 0.2 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0 0.3 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.3 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.7 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.1 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.6 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.8 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.1 GO:0097322 7SK snRNA binding(GO:0097322)
0.0 0.2 GO:0005549 odorant binding(GO:0005549)
0.0 0.4 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.3 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 0.2 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.5 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.3 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.1 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.3 GO:0031489 myosin V binding(GO:0031489)
0.0 0.1 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 0.3 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.8 GO:0097110 scaffold protein binding(GO:0097110)
0.0 0.1 GO:0008422 beta-glucosidase activity(GO:0008422)
0.0 0.1 GO:0009378 four-way junction helicase activity(GO:0009378)
0.0 0.4 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.0 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 0.4 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 1.3 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.1 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 0.2 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 0.4 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.5 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 1.2 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.4 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.2 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.6 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.8 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.1 1.0 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.1 0.8 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.1 0.8 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.1 0.9 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.7 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.4 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.8 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.4 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.0 0.6 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.5 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.3 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.3 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.3 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.7 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.1 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.3 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.4 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.3 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.7 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.6 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.5 REACTOME CELL CELL JUNCTION ORGANIZATION Genes involved in Cell-cell junction organization
0.0 0.2 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 2.2 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 0.4 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.2 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.3 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.6 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors
0.0 0.2 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.4 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.7 REACTOME TRANSPORT OF GLUCOSE AND OTHER SUGARS BILE SALTS AND ORGANIC ACIDS METAL IONS AND AMINE COMPOUNDS Genes involved in Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds
0.0 0.3 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA