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2D miR_HR1_12

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Results for Tcf3

Z-value: 0.93

Motif logo

Transcription factors associated with Tcf3

Gene Symbol Gene ID Gene Info
ENSMUSG00000020167.8 transcription factor 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Tcf3mm10_v2_chr10_-_80433615_80433655-0.681.5e-02Click!

Activity profile of Tcf3 motif

Sorted Z-values of Tcf3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr10_+_127866457 1.72 ENSMUST00000092058.3
cDNA sequence BC089597
chr2_-_152933202 1.64 ENSMUST00000099200.2
forkhead box S1
chr11_-_120648104 1.63 ENSMUST00000026134.2
myeloid-associated differentiation marker-like 2
chr7_-_19796789 1.60 ENSMUST00000108449.2
ENSMUST00000043822.7
Casitas B-lineage lymphoma c
chr2_+_70562007 1.52 ENSMUST00000094934.4
glutamate decarboxylase 1
chr11_+_69965396 1.51 ENSMUST00000018713.6
claudin 7
chr11_+_98664341 1.34 ENSMUST00000017348.2
gasdermin A
chr11_-_95514570 1.27 ENSMUST00000058866.7
neurexophilin 3
chr2_+_70562147 1.27 ENSMUST00000148210.1
glutamate decarboxylase 1
chr12_-_17176888 1.27 ENSMUST00000170580.1
potassium voltage-gated channel, subfamily F, member 1
chr4_-_42168603 1.24 ENSMUST00000098121.3
predicted gene 13305
chr13_-_71963713 1.21 ENSMUST00000077337.8
Iroquois related homeobox 1 (Drosophila)
chr2_+_174760619 1.19 ENSMUST00000029030.2
endothelin 3
chr14_-_57104693 1.18 ENSMUST00000055698.7
gap junction protein, beta 2
chr16_-_22439570 1.18 ENSMUST00000170393.1
ets variant gene 5
chrX_+_101383726 1.17 ENSMUST00000119190.1
gap junction protein, beta 1
chr6_+_30639218 1.09 ENSMUST00000031806.9
carboxypeptidase A1, pancreatic
chr7_+_141079759 1.08 ENSMUST00000066873.4
ENSMUST00000163041.1
plakophilin 3
chr3_+_89436699 1.05 ENSMUST00000038942.3
ENSMUST00000130858.1
pre B cell leukemia transcription factor interacting protein 1
chr3_+_89436736 1.03 ENSMUST00000146630.1
ENSMUST00000145753.1
pre B cell leukemia transcription factor interacting protein 1
chr8_+_105305572 1.02 ENSMUST00000109375.2
engulfment and cell motility 3
chr8_-_105933832 1.02 ENSMUST00000034368.6
chymotrypsin-like
chr6_-_41377604 1.01 ENSMUST00000096003.5
protease, serine, 3
chr15_-_101850778 0.94 ENSMUST00000023790.3
keratin 1
chr16_-_22439719 0.92 ENSMUST00000079601.6
ets variant gene 5
chr1_-_171437288 0.90 ENSMUST00000181499.1
predicted gene, 26641
chr12_-_32953772 0.87 ENSMUST00000180391.1
ENSMUST00000181670.1
RIKEN cDNA 4933406C10 gene
chr17_+_47436615 0.87 ENSMUST00000037701.6
expressed sequence AI661453
chr11_-_119086221 0.86 ENSMUST00000026665.7
chromobox 4
chr11_+_113619318 0.85 ENSMUST00000146390.2
ENSMUST00000106630.1
somatostatin receptor 2
chr5_+_144545883 0.84 ENSMUST00000071782.6
neuronal pentraxin 2
chr11_+_32000452 0.84 ENSMUST00000020537.2
ENSMUST00000109409.1
neuron specific gene family member 2
chr18_+_74442500 0.84 ENSMUST00000074157.6
myosin VB
chr11_-_109722214 0.82 ENSMUST00000020938.7
family with sequence similarity 20, member A
chr2_+_174760781 0.80 ENSMUST00000140908.1
endothelin 3
chr6_+_56017489 0.80 ENSMUST00000052827.4
protein phosphatase 1, regulatory subunit 17
chr9_+_59589288 0.80 ENSMUST00000121266.1
ENSMUST00000118164.1
CUGBP, Elav-like family member 6
chr13_-_92131494 0.79 ENSMUST00000099326.3
ENSMUST00000146492.1
RAS protein-specific guanine nucleotide-releasing factor 2
chr11_-_72489904 0.78 ENSMUST00000045303.3
spinster homolog 2
chr6_-_72235559 0.78 ENSMUST00000042646.7
atonal homolog 8 (Drosophila)
chr3_-_107986408 0.77 ENSMUST00000012348.2
glutathione S-transferase, mu 2
chr1_+_75507077 0.75 ENSMUST00000037330.4
inhibin alpha
chr3_-_107986360 0.75 ENSMUST00000066530.6
glutathione S-transferase, mu 2
chr12_+_108334341 0.74 ENSMUST00000021684.4
cytochrome P450, family 46, subfamily a, polypeptide 1
chr19_-_36119833 0.73 ENSMUST00000025718.8
ankyrin repeat domain 1 (cardiac muscle)
chr14_+_54936456 0.72 ENSMUST00000037814.6
CKLF-like MARVEL transmembrane domain containing 5
chr1_-_135375233 0.72 ENSMUST00000041240.3
shisa homolog 4 (Xenopus laevis)
chr17_+_47436731 0.71 ENSMUST00000150819.2
expressed sequence AI661453
chr11_+_53519920 0.70 ENSMUST00000147912.1
septin 8
chr10_-_109010955 0.69 ENSMUST00000105276.1
ENSMUST00000064054.7
synaptotagmin I
chr7_+_122289297 0.68 ENSMUST00000064989.5
ENSMUST00000064921.4
protein kinase C, beta
chr4_-_43523595 0.67 ENSMUST00000107914.3
tropomyosin 2, beta
chr3_-_75270073 0.67 ENSMUST00000039047.4
serine (or cysteine) peptidase inhibitor, clade I, member 2
chr6_+_97807014 0.67 ENSMUST00000043637.7
microphthalmia-associated transcription factor
chr15_-_100599983 0.67 ENSMUST00000073837.6
POU domain, class 6, transcription factor 1
chr7_+_28071230 0.66 ENSMUST00000138392.1
ENSMUST00000076648.7
Fc fragment of IgG binding protein
chr6_+_118066356 0.66 ENSMUST00000164960.1
RasGEF domain family, member 1A
chr13_-_95444827 0.66 ENSMUST00000045583.7
corticotropin releasing hormone binding protein
chr6_+_41392356 0.66 ENSMUST00000049079.7
predicted gene 5771
chr16_-_31314804 0.65 ENSMUST00000115230.1
ENSMUST00000130560.1
apolipoprotein D
chr5_+_102724971 0.65 ENSMUST00000112853.1
Rho GTPase activating protein 24
chr2_-_28563362 0.64 ENSMUST00000028161.5
carboxyl ester lipase
chr14_+_41105359 0.64 ENSMUST00000047286.6
methionine adenosyltransferase I, alpha
chr9_-_39604124 0.64 ENSMUST00000042485.4
ENSMUST00000141370.1
expressed sequence AW551984
chr4_-_148149684 0.63 ENSMUST00000126615.1
F-box protein 6
chr2_-_25196759 0.63 ENSMUST00000081869.6
torsin family 4, member A
chr9_-_121759788 0.62 ENSMUST00000181325.1
RIKEN cDNA E530011L22 gene
chr9_-_108567336 0.62 ENSMUST00000074208.4
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 3
chr7_-_44815658 0.62 ENSMUST00000107893.1
activating transcription factor 5
chr11_-_100146120 0.62 ENSMUST00000007317.7
keratin 19
chr3_-_20275659 0.60 ENSMUST00000011607.5
carboxypeptidase B1 (tissue)
chr5_-_110343009 0.60 ENSMUST00000058016.9
ENSMUST00000112478.3
purinergic receptor P2X, ligand-gated ion channel, 2
chr18_-_44662251 0.59 ENSMUST00000164666.1
mutated in colorectal cancers
chr4_-_156059414 0.59 ENSMUST00000184348.1
tubulin tyrosine ligase-like family, member 10
chr9_+_121760000 0.59 ENSMUST00000093772.3
zinc finger protein 651
chr7_+_19094594 0.58 ENSMUST00000049454.5
sine oculis-related homeobox 5
chr2_-_121807024 0.58 ENSMUST00000138157.1
FERM domain containing 5
chr12_-_101819048 0.57 ENSMUST00000021603.8
fibulin 5
chr15_-_71727815 0.56 ENSMUST00000022953.8
family with sequence similarity 135, member B
chr4_+_99295900 0.56 ENSMUST00000094955.1
predicted gene 12689
chr11_+_53519871 0.56 ENSMUST00000120878.2
septin 8
chr7_-_126625676 0.55 ENSMUST00000032961.3
nuclear protein transcription regulator 1
chr11_-_101894355 0.55 ENSMUST00000057054.7
mesenchyme homeobox 1
chr4_+_139380658 0.55 ENSMUST00000165860.1
ENSMUST00000097822.3
ubiquitin protein ligase E3 component n-recognin 4
chr9_+_114978507 0.55 ENSMUST00000183104.1
oxysterol binding protein-like 10
chr11_+_96929260 0.55 ENSMUST00000054311.5
ENSMUST00000107636.3
proline rich 15-like
chr11_+_45980309 0.54 ENSMUST00000049038.3
SRY-box containing gene 30
chr9_-_58159201 0.54 ENSMUST00000041477.7
immunoglobulin superfamily containing leucine-rich repeat
chr6_-_124738714 0.54 ENSMUST00000171549.2
protein tyrosine phosphatase, non-receptor type 6
chr6_+_49367739 0.53 ENSMUST00000060561.8
ENSMUST00000121903.1
ENSMUST00000134786.1
family with sequence similarity 221, member A
chr8_-_105255100 0.53 ENSMUST00000093217.2
ENSMUST00000161745.2
ENSMUST00000136822.2
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9
chrX_-_57338598 0.52 ENSMUST00000033468.4
ENSMUST00000114736.1
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr2_-_168741752 0.52 ENSMUST00000029060.4
ATPase, class II, type 9A
chr10_+_81633694 0.51 ENSMUST00000140345.1
ENSMUST00000126323.1
ankyrin repeat domain 24
chr15_+_78926720 0.51 ENSMUST00000089377.5
lectin, galactose binding, soluble 1
chr11_+_96929367 0.51 ENSMUST00000062172.5
proline rich 15-like
chr6_-_41314700 0.50 ENSMUST00000064324.5
trypsin 5
chr16_-_34095983 0.50 ENSMUST00000114973.1
ENSMUST00000114964.1
kalirin, RhoGEF kinase
chr7_-_97332017 0.50 ENSMUST00000139582.2
ubiquitin specific peptidase 35
chr7_-_29168647 0.50 ENSMUST00000048923.6
sprouty-related, EVH1 domain containing 3
chr2_+_84734050 0.49 ENSMUST00000090729.2
yippee-like 4 (Drosophila)
chr6_-_84593810 0.49 ENSMUST00000077705.3
ENSMUST00000168003.2
cytochrome P450, family 26, subfamily b, polypeptide 1
chr3_+_95588960 0.49 ENSMUST00000176674.1
ENSMUST00000177389.1
ENSMUST00000176755.1
golgi phosphoprotein 3-like
chr8_-_84011442 0.48 ENSMUST00000056686.5
RIKEN cDNA 2210011C24 gene
chr12_-_79007276 0.48 ENSMUST00000056660.6
ENSMUST00000174721.1
transmembrane protein 229B
chr6_+_47244359 0.48 ENSMUST00000060839.6
contactin associated protein-like 2
chr12_+_113014502 0.48 ENSMUST00000084891.4
phosphofurin acidic cluster sorting protein 2
chr7_-_31126945 0.48 ENSMUST00000098548.4
sodium channel, voltage-gated, type I, beta
chr10_+_87859481 0.47 ENSMUST00000121952.1
insulin-like growth factor 1
chr4_+_137862237 0.47 ENSMUST00000102518.3
endothelin converting enzyme 1
chr6_+_41458923 0.47 ENSMUST00000031910.7
protease, serine, 1 (trypsin 1)
chr16_+_20696175 0.47 ENSMUST00000128273.1
family with sequence similarity 131, member A
chr19_+_53529100 0.47 ENSMUST00000038287.6
dual specificity phosphatase 5
chr16_+_20733104 0.47 ENSMUST00000115423.1
ENSMUST00000007171.6
chordin
chr5_+_102768771 0.47 ENSMUST00000112852.1
Rho GTPase activating protein 24
chr3_+_125404292 0.46 ENSMUST00000144344.1
N-deacetylase/N-sulfotransferase (heparin glucosaminyl) 4
chr7_+_44207307 0.45 ENSMUST00000077354.4
kallikrein 1-related pepidase b4
chr8_+_45885479 0.44 ENSMUST00000034053.5
PDZ and LIM domain 3
chr7_-_30457515 0.44 ENSMUST00000045817.7
kin of IRRE like 2 (Drosophila)
chr12_+_26469204 0.44 ENSMUST00000020969.3
cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial
chr3_+_95588928 0.44 ENSMUST00000177390.1
ENSMUST00000098861.4
ENSMUST00000060323.5
golgi phosphoprotein 3-like
chr17_+_75178911 0.44 ENSMUST00000112514.1
latent transforming growth factor beta binding protein 1
chr6_-_124738579 0.44 ENSMUST00000174265.1
ENSMUST00000004377.8
protein tyrosine phosphatase, non-receptor type 6
chr3_+_125404072 0.44 ENSMUST00000173932.1
N-deacetylase/N-sulfotransferase (heparin glucosaminyl) 4
chr1_-_153186447 0.44 ENSMUST00000027753.6
laminin, gamma 2
chr2_-_168230575 0.44 ENSMUST00000109193.1
dolichol-phosphate (beta-D) mannosyltransferase 1
chr5_-_24351604 0.43 ENSMUST00000036092.7
potassium voltage-gated channel, subfamily H (eag-related), member 2
chr8_+_53511695 0.42 ENSMUST00000033920.4
aspartylglucosaminidase
chr2_-_168230353 0.42 ENSMUST00000154111.1
dolichol-phosphate (beta-D) mannosyltransferase 1
chr9_+_109095427 0.42 ENSMUST00000072093.6
plexin B1
chr8_-_122699066 0.42 ENSMUST00000127984.1
core-binding factor, runt domain, alpha subunit 2, translocated to, 3 (human)
chr11_+_70764209 0.42 ENSMUST00000060444.5
zinc finger protein 3
chr8_+_23139030 0.42 ENSMUST00000121075.1
ankyrin 1, erythroid
chr19_+_4510472 0.41 ENSMUST00000068004.6
pyruvate carboxylase
chr1_+_180935022 0.41 ENSMUST00000037361.8
left right determination factor 1
chr7_+_80246529 0.41 ENSMUST00000107381.1
tubulin tyrosine ligase-like family, member 13
chr3_+_27154020 0.41 ENSMUST00000181124.1
RIKEN cDNA 1700125G22 gene
chr9_-_71771535 0.40 ENSMUST00000122065.1
ENSMUST00000121322.1
ENSMUST00000072899.2
cingulin-like 1
chrX_-_73869804 0.40 ENSMUST00000066576.5
ENSMUST00000114430.1
L1 cell adhesion molecule
chr1_-_166409773 0.40 ENSMUST00000135673.1
ENSMUST00000079972.6
ENSMUST00000169324.1
ENSMUST00000111411.2
ENSMUST00000128861.1
pogo transposable element with KRAB domain
chr4_-_106799779 0.40 ENSMUST00000145061.1
ENSMUST00000102762.3
acyl-CoA thioesterase 11
chr2_-_127521358 0.40 ENSMUST00000028850.8
ENSMUST00000103215.4
Kv channel interacting protein 3, calsenilin
chr2_-_131187282 0.40 ENSMUST00000028801.1
sperm flagellar 1
chr7_-_4964333 0.40 ENSMUST00000182214.1
ENSMUST00000032598.7
ENSMUST00000183170.1
SH3-binding domain kinase family, member 2
chr5_-_137212389 0.39 ENSMUST00000179412.1
RIKEN cDNA A630081J09 gene
chr3_+_96246685 0.39 ENSMUST00000176059.1
ENSMUST00000177796.1
histone cluster 2, H3c1
chr2_+_127854628 0.39 ENSMUST00000028859.1
acyl-Coenzyme A oxidase-like
chr11_-_69122589 0.39 ENSMUST00000180487.1
RIKEN cDNA 9130213A22 gene
chr11_+_121434913 0.38 ENSMUST00000026175.2
ENSMUST00000092302.4
ENSMUST00000103014.3
fructosamine 3 kinase
chr3_-_41082992 0.38 ENSMUST00000058578.7
progesterone receptor membrane component 2
chr7_-_16874845 0.38 ENSMUST00000181501.1
RIKEN cDNA 9330104G04 gene
chr17_+_75178797 0.38 ENSMUST00000112516.1
ENSMUST00000135447.1
latent transforming growth factor beta binding protein 1
chr6_-_148444336 0.38 ENSMUST00000060095.8
ENSMUST00000100772.3
transmembrane and tetratricopeptide repeat containing 1
chr11_+_87664274 0.38 ENSMUST00000092800.5
ring finger protein 43
chr11_-_71019233 0.37 ENSMUST00000108523.3
ENSMUST00000143850.1
Der1-like domain family, member 2
chr8_-_71511762 0.37 ENSMUST00000048452.4
plasmalemma vesicle associated protein
chr19_-_58454435 0.37 ENSMUST00000169850.1
glial cell line derived neurotrophic factor family receptor alpha 1
chr11_+_48837465 0.37 ENSMUST00000046903.5
tripartite motif-containing 7
chr14_+_31641051 0.37 ENSMUST00000090147.6
biotinidase
chr6_+_88724828 0.37 ENSMUST00000089449.2
monoglyceride lipase
chr15_-_89477400 0.36 ENSMUST00000165199.1
arylsulfatase A
chr3_+_95588990 0.36 ENSMUST00000177399.1
golgi phosphoprotein 3-like
chr2_-_121806988 0.36 ENSMUST00000110592.1
FERM domain containing 5
chr2_-_64097994 0.36 ENSMUST00000131615.2
fidgetin
chr4_+_140906344 0.36 ENSMUST00000030765.6
peptidyl arginine deiminase, type II
chr14_+_27039001 0.35 ENSMUST00000035336.3
interleukin 17 receptor D
chr16_+_93683184 0.35 ENSMUST00000039620.6
carbonyl reductase 3
chrX_+_143664290 0.35 ENSMUST00000112868.1
p21 protein (Cdc42/Rac)-activated kinase 3
chr1_+_135324770 0.35 ENSMUST00000059352.2
leiomodin 1 (smooth muscle)
chr7_+_80246375 0.35 ENSMUST00000058266.6
tubulin tyrosine ligase-like family, member 13
chr10_+_19934472 0.34 ENSMUST00000095806.3
ENSMUST00000120259.1
mitogen-activated protein kinase kinase kinase 5
chr7_-_105482197 0.34 ENSMUST00000047040.2
protein kinase C, delta binding protein
chr2_+_27079371 0.34 ENSMUST00000091233.6
ADAMTS-like 2
chr12_+_69893105 0.34 ENSMUST00000021466.8
atlastin GTPase 1
chr3_-_133234886 0.33 ENSMUST00000147041.3
ENSMUST00000161022.2
Rho guanine nucleotide exchange factor (GEF) 38
chr2_-_30474199 0.33 ENSMUST00000065134.2
immediate early response 5-like
chr5_+_123015010 0.33 ENSMUST00000121652.1
ENSMUST00000051016.4
ORAI calcium release-activated calcium modulator 1
chr5_+_117357274 0.33 ENSMUST00000031309.9
WD repeat and SOCS box-containing 2
chr10_-_127888688 0.33 ENSMUST00000047199.4
retinol dehydrogenase 7
chrX_+_143664365 0.33 ENSMUST00000126592.1
ENSMUST00000156449.1
ENSMUST00000155215.1
ENSMUST00000112865.1
p21 protein (Cdc42/Rac)-activated kinase 3
chr2_+_91035613 0.33 ENSMUST00000111445.3
ENSMUST00000111446.3
ENSMUST00000050323.5
receptor-associated protein of the synapse
chr9_+_121777607 0.33 ENSMUST00000098272.2
kelch-like 40
chr11_+_19924354 0.33 ENSMUST00000093299.6
sprouty-related, EVH1 domain containing 2
chr15_+_99591028 0.33 ENSMUST00000169082.1
aquaporin 5
chr2_+_163225363 0.33 ENSMUST00000099110.3
ENSMUST00000165937.1
TOX high mobility group box family member 2
chr10_-_128744014 0.33 ENSMUST00000026414.7
diacylglycerol kinase, alpha
chr7_+_45639964 0.32 ENSMUST00000148532.1
MEF2 activating motif and SAP domain containing transcriptional regulator
chr1_+_162639148 0.32 ENSMUST00000028020.9
myocilin
chr11_-_69605829 0.32 ENSMUST00000047889.6
ATPase, Na+/K+ transporting, beta 2 polypeptide
chrX_-_59134421 0.32 ENSMUST00000033473.5
fibroblast growth factor 13
chr14_-_31640878 0.32 ENSMUST00000167066.1
ENSMUST00000127204.2
ENSMUST00000022437.8
2-hydroxyacyl-CoA lyase 1
chr3_-_89387132 0.32 ENSMUST00000107433.1
zinc finger and BTB domain containing 7B
chr8_+_25518757 0.32 ENSMUST00000178276.1
ENSMUST00000179592.1
fibroblast growth factor receptor 1
chr6_-_53820764 0.32 ENSMUST00000127748.2
TLR4 interactor with leucine-rich repeats
chr3_+_32817520 0.32 ENSMUST00000072312.5
ENSMUST00000108228.1
ubiquitin specific peptidase 13 (isopeptidase T-3)
chr5_+_30888852 0.32 ENSMUST00000069705.4
ENSMUST00000031057.8
ENSMUST00000046182.5
ENSMUST00000114704.1
ENSMUST00000061213.6
ENSMUST00000114696.1
ENSMUST00000114700.2
ATP/GTP binding protein-like 5
chr9_-_50528641 0.32 ENSMUST00000034570.5
6-pyruvoyl-tetrahydropterin synthase
chr5_-_30907692 0.31 ENSMUST00000132034.2
ENSMUST00000132253.2
oligosaccharyltransferase 4 homolog (S. cerevisiae)
chr8_+_83165348 0.31 ENSMUST00000034145.4
TBC1 domain family, member 9
chr10_-_19851459 0.31 ENSMUST00000059805.4
solute carrier family 35, member D3

Network of associatons between targets according to the STRING database.

First level regulatory network of Tcf3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.8 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.3 2.0 GO:0003100 regulation of systemic arterial blood pressure by endothelin(GO:0003100) vein smooth muscle contraction(GO:0014826)
0.3 2.0 GO:0098728 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.3 1.2 GO:0072272 proximal/distal pattern formation involved in metanephric nephron development(GO:0072272)
0.3 1.0 GO:2000402 negative regulation of lymphocyte migration(GO:2000402)
0.2 0.7 GO:0070268 cornification(GO:0070268)
0.2 0.7 GO:0071314 cellular response to cocaine(GO:0071314)
0.2 1.5 GO:0051410 detoxification of nitrogen compound(GO:0051410) cellular detoxification of nitrogen compound(GO:0070458)
0.2 0.6 GO:0010816 substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.2 0.6 GO:1903465 motogenic signaling involved in postnatal olfactory bulb interneuron migration(GO:0021837) positive regulation of mitotic cell cycle DNA replication(GO:1903465)
0.2 1.0 GO:0033277 abortive mitotic cell cycle(GO:0033277)
0.2 0.6 GO:0090341 negative regulation of secretion of lysosomal enzymes(GO:0090341)
0.2 0.2 GO:0072268 pattern specification involved in metanephros development(GO:0072268)
0.2 0.7 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.2 0.5 GO:2000832 negative regulation of steroid hormone secretion(GO:2000832)
0.2 0.6 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.2 0.5 GO:0086047 corticospinal neuron axon guidance(GO:0021966) membrane depolarization during Purkinje myocyte cell action potential(GO:0086047)
0.2 0.8 GO:0032277 negative regulation of gonadotropin secretion(GO:0032277) negative regulation of follicle-stimulating hormone secretion(GO:0046882)
0.1 0.9 GO:0002159 desmosome assembly(GO:0002159)
0.1 0.4 GO:0009139 dUDP biosynthetic process(GO:0006227) pyrimidine nucleoside diphosphate metabolic process(GO:0009138) pyrimidine nucleoside diphosphate biosynthetic process(GO:0009139) pyrimidine deoxyribonucleoside diphosphate metabolic process(GO:0009196) pyrimidine deoxyribonucleoside diphosphate biosynthetic process(GO:0009197) dUDP metabolic process(GO:0046077)
0.1 0.8 GO:0032439 endosome localization(GO:0032439)
0.1 0.6 GO:0061056 sclerotome development(GO:0061056)
0.1 0.4 GO:0019072 viral genome packaging(GO:0019072) viral RNA genome packaging(GO:0019074)
0.1 0.4 GO:0061033 secretion by lung epithelial cell involved in lung growth(GO:0061033)
0.1 1.1 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.1 0.9 GO:0019348 dolichol metabolic process(GO:0019348)
0.1 0.9 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.1 0.4 GO:0042376 phylloquinone metabolic process(GO:0042374) phylloquinone catabolic process(GO:0042376) quinone catabolic process(GO:1901662)
0.1 1.4 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.1 0.8 GO:0048069 eye pigmentation(GO:0048069)
0.1 0.3 GO:0098528 skeletal muscle fiber differentiation(GO:0098528)
0.1 0.7 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.1 0.4 GO:1902303 negative regulation of potassium ion export(GO:1902303)
0.1 1.2 GO:0015868 purine ribonucleotide transport(GO:0015868)
0.1 0.4 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.1 0.3 GO:0044313 protein K6-linked deubiquitination(GO:0044313)
0.1 0.3 GO:0090481 pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.1 0.4 GO:1900108 negative regulation of nodal signaling pathway(GO:1900108)
0.1 0.3 GO:0072034 renal vesicle induction(GO:0072034) metanephric nephron tubule formation(GO:0072289)
0.1 0.3 GO:1902630 regulation of membrane hyperpolarization(GO:1902630)
0.1 1.2 GO:0030432 peristalsis(GO:0030432)
0.1 0.3 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.1 0.6 GO:0018094 protein polyglycylation(GO:0018094)
0.1 1.1 GO:0070166 enamel mineralization(GO:0070166)
0.1 0.5 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.1 0.3 GO:0097051 establishment of protein localization to endoplasmic reticulum membrane(GO:0097051)
0.1 0.5 GO:0021914 negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
0.1 1.5 GO:0016264 gap junction assembly(GO:0016264)
0.1 1.3 GO:0048194 Golgi vesicle budding(GO:0048194)
0.1 1.6 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.1 0.5 GO:0002317 plasma cell differentiation(GO:0002317)
0.1 0.8 GO:0021891 olfactory bulb interneuron development(GO:0021891)
0.1 0.2 GO:1900060 negative regulation of ceramide biosynthetic process(GO:1900060)
0.1 0.3 GO:0014734 skeletal muscle hypertrophy(GO:0014734)
0.1 0.3 GO:1903286 regulation of potassium ion import(GO:1903286) positive regulation of potassium ion import(GO:1903288)
0.1 0.3 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.1 1.5 GO:0032463 negative regulation of protein homooligomerization(GO:0032463)
0.1 0.2 GO:1902022 L-lysine transport(GO:1902022)
0.1 0.5 GO:1904073 regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
0.1 0.7 GO:0005513 detection of calcium ion(GO:0005513)
0.1 0.3 GO:0001802 type III hypersensitivity(GO:0001802) regulation of type III hypersensitivity(GO:0001803) positive regulation of type III hypersensitivity(GO:0001805)
0.1 0.3 GO:0033575 protein glycosylation at cell surface(GO:0033575) protein galactosylation at cell surface(GO:0033580) protein galactosylation(GO:0042125)
0.1 0.6 GO:0061366 behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.1 0.3 GO:0006680 glucosylceramide catabolic process(GO:0006680)
0.1 1.1 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.1 0.1 GO:0010593 negative regulation of lamellipodium assembly(GO:0010593)
0.1 0.1 GO:0014064 positive regulation of serotonin secretion(GO:0014064)
0.1 0.2 GO:0061552 vestibulocochlear nerve structural organization(GO:0021649) ganglion morphogenesis(GO:0061552) dorsal root ganglion morphogenesis(GO:1904835)
0.1 0.3 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.1 0.2 GO:0046351 disaccharide biosynthetic process(GO:0046351)
0.1 0.3 GO:1902953 positive regulation by virus of viral protein levels in host cell(GO:0046726) positive regulation of ER to Golgi vesicle-mediated transport(GO:1902953)
0.1 0.2 GO:0034635 glutathione transport(GO:0034635) tripeptide transport(GO:0042939)
0.1 0.4 GO:0098909 regulation of cardiac muscle cell action potential involved in regulation of contraction(GO:0098909)
0.1 0.6 GO:0060923 cardiac muscle cell fate commitment(GO:0060923)
0.1 0.3 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)
0.1 0.2 GO:0061642 chemoattraction of axon(GO:0061642) inner medullary collecting duct development(GO:0072061)
0.1 0.4 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.1 0.7 GO:0006517 protein deglycosylation(GO:0006517)
0.1 0.4 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.1 0.6 GO:0048251 elastic fiber assembly(GO:0048251)
0.1 0.2 GO:0006713 glucocorticoid catabolic process(GO:0006713)
0.0 0.1 GO:0002074 extraocular skeletal muscle development(GO:0002074)
0.0 0.1 GO:0010752 regulation of cGMP-mediated signaling(GO:0010752)
0.0 0.3 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.1 GO:0021577 hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589)
0.0 0.7 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0 0.1 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.0 0.7 GO:0014841 skeletal muscle satellite cell proliferation(GO:0014841)
0.0 0.6 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.0 0.1 GO:0009804 coumarin metabolic process(GO:0009804)
0.0 0.8 GO:0071625 vocalization behavior(GO:0071625)
0.0 0.4 GO:0035608 protein deglutamylation(GO:0035608)
0.0 0.3 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.8 GO:0051450 myoblast proliferation(GO:0051450)
0.0 0.2 GO:1902202 regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.0 0.3 GO:0042904 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0 0.3 GO:0015670 carbon dioxide transport(GO:0015670)
0.0 0.2 GO:0034351 negative regulation of glial cell apoptotic process(GO:0034351)
0.0 0.1 GO:2000040 regulation of planar cell polarity pathway involved in axis elongation(GO:2000040) negative regulation of planar cell polarity pathway involved in axis elongation(GO:2000041)
0.0 0.2 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.6 GO:2000194 regulation of female gonad development(GO:2000194)
0.0 0.3 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.0 0.1 GO:0060032 spinal cord ventral commissure morphogenesis(GO:0021965) notochord regression(GO:0060032)
0.0 0.3 GO:0030382 sperm mitochondrion organization(GO:0030382)
0.0 0.3 GO:0006701 progesterone biosynthetic process(GO:0006701)
0.0 0.2 GO:0014043 negative regulation of neuron maturation(GO:0014043)
0.0 0.2 GO:2000465 regulation of glycogen (starch) synthase activity(GO:2000465)
0.0 0.1 GO:0045014 carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
0.0 0.1 GO:0018307 enzyme active site formation(GO:0018307)
0.0 0.3 GO:0003096 renal sodium ion transport(GO:0003096) renal sodium ion absorption(GO:0070294)
0.0 0.7 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.0 0.5 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.9 GO:0010763 positive regulation of fibroblast migration(GO:0010763)
0.0 0.1 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.0 0.2 GO:1901678 iron coordination entity transport(GO:1901678)
0.0 0.2 GO:0042758 long-chain fatty acid catabolic process(GO:0042758)
0.0 0.1 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.0 0.3 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729)
0.0 0.4 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.0 0.2 GO:0045590 regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124) negative regulation of regulatory T cell differentiation(GO:0045590)
0.0 1.7 GO:0040018 positive regulation of multicellular organism growth(GO:0040018)
0.0 0.2 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.0 0.5 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.0 0.1 GO:0032224 positive regulation of synaptic transmission, cholinergic(GO:0032224)
0.0 0.2 GO:0032485 regulation of Ral protein signal transduction(GO:0032485)
0.0 0.2 GO:0001830 trophectodermal cell fate commitment(GO:0001830)
0.0 0.2 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.0 0.9 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.2 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.0 0.8 GO:0032967 positive regulation of collagen metabolic process(GO:0010714) positive regulation of collagen biosynthetic process(GO:0032967) positive regulation of multicellular organismal metabolic process(GO:0044253)
0.0 0.3 GO:0071285 cellular response to lithium ion(GO:0071285)
0.0 0.1 GO:2000451 positive regulation of CD8-positive, alpha-beta T cell extravasation(GO:2000451)
0.0 0.6 GO:1900745 positive regulation of p38MAPK cascade(GO:1900745)
0.0 0.1 GO:0061763 multivesicular body-lysosome fusion(GO:0061763)
0.0 0.8 GO:2000310 regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310)
0.0 0.1 GO:0038032 termination of G-protein coupled receptor signaling pathway(GO:0038032)
0.0 0.2 GO:0098903 regulation of membrane repolarization during action potential(GO:0098903)
0.0 0.1 GO:0050917 sensory perception of umami taste(GO:0050917)
0.0 0.1 GO:0003266 regulation of secondary heart field cardioblast proliferation(GO:0003266)
0.0 0.4 GO:0044336 canonical Wnt signaling pathway involved in negative regulation of apoptotic process(GO:0044336)
0.0 0.2 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.0 0.3 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.0 0.2 GO:0034154 toll-like receptor 7 signaling pathway(GO:0034154)
0.0 0.5 GO:0070831 basement membrane assembly(GO:0070831)
0.0 0.2 GO:1902732 positive regulation of chondrocyte proliferation(GO:1902732)
0.0 0.2 GO:1902004 positive regulation of beta-amyloid formation(GO:1902004)
0.0 0.4 GO:0002693 positive regulation of cellular extravasation(GO:0002693)
0.0 2.8 GO:0007586 digestion(GO:0007586)
0.0 0.3 GO:0060481 lobar bronchus epithelium development(GO:0060481)
0.0 0.1 GO:2001137 positive regulation of endocytic recycling(GO:2001137)
0.0 0.2 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.0 0.8 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.1 GO:0001712 ectodermal cell fate commitment(GO:0001712)
0.0 0.1 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
0.0 0.3 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
0.0 0.1 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.0 GO:0016332 establishment or maintenance of polarity of embryonic epithelium(GO:0016332)
0.0 0.1 GO:0007341 penetration of zona pellucida(GO:0007341) notochord formation(GO:0014028)
0.0 0.1 GO:0071799 response to prostaglandin D(GO:0071798) cellular response to prostaglandin D stimulus(GO:0071799)
0.0 0.1 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.0 0.2 GO:0042473 outer ear morphogenesis(GO:0042473)
0.0 0.6 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.2 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.1 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.3 GO:0002115 store-operated calcium entry(GO:0002115)
0.0 0.1 GO:0014850 response to muscle activity(GO:0014850)
0.0 0.1 GO:0010025 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.0 0.2 GO:0097369 sodium ion import(GO:0097369) sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.6 GO:0045022 early endosome to late endosome transport(GO:0045022)
0.0 0.3 GO:0048266 behavioral response to pain(GO:0048266)
0.0 0.0 GO:2000680 regulation of rubidium ion transport(GO:2000680)
0.0 0.1 GO:0060011 Sertoli cell proliferation(GO:0060011)
0.0 0.1 GO:0098989 NMDA selective glutamate receptor signaling pathway(GO:0098989) protein localization to postsynaptic specialization membrane(GO:0099633) neurotransmitter receptor localization to postsynaptic specialization membrane(GO:0099645)
0.0 0.1 GO:0014062 regulation of serotonin secretion(GO:0014062)
0.0 0.3 GO:0051895 negative regulation of focal adhesion assembly(GO:0051895) negative regulation of adherens junction organization(GO:1903392)
0.0 0.3 GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
0.0 0.6 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.5 GO:0015914 phospholipid transport(GO:0015914)
0.0 0.3 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.0 0.2 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.0 0.4 GO:0010842 retina layer formation(GO:0010842)
0.0 0.1 GO:0090214 spongiotrophoblast layer developmental growth(GO:0090214)
0.0 0.7 GO:0016925 protein sumoylation(GO:0016925)
0.0 0.6 GO:0045214 sarcomere organization(GO:0045214)
0.0 0.3 GO:0007271 synaptic transmission, cholinergic(GO:0007271)
0.0 0.5 GO:0009268 response to pH(GO:0009268)
0.0 0.2 GO:0010225 response to UV-C(GO:0010225)
0.0 0.8 GO:0046579 positive regulation of Ras protein signal transduction(GO:0046579)
0.0 0.6 GO:0010633 negative regulation of epithelial cell migration(GO:0010633)
0.0 0.2 GO:0030574 collagen catabolic process(GO:0030574) multicellular organism catabolic process(GO:0044243)
0.0 0.1 GO:0060033 anatomical structure regression(GO:0060033)
0.0 0.4 GO:0006767 water-soluble vitamin metabolic process(GO:0006767)
0.0 0.3 GO:0010831 positive regulation of myotube differentiation(GO:0010831)
0.0 0.0 GO:0021594 rhombomere formation(GO:0021594) rhombomere 3 formation(GO:0021660) rhombomere 5 morphogenesis(GO:0021664) rhombomere 5 formation(GO:0021666)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0038045 large latent transforming growth factor-beta complex(GO:0038045)
0.3 1.1 GO:0005914 spot adherens junction(GO:0005914)
0.3 0.8 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.2 0.9 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.1 0.4 GO:0005607 laminin-2 complex(GO:0005607)
0.1 0.6 GO:0071953 elastic fiber(GO:0071953)
0.1 2.4 GO:0005922 connexon complex(GO:0005922)
0.1 0.4 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.1 0.3 GO:0036488 CHOP-C/EBP complex(GO:0036488)
0.1 0.9 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.1 0.3 GO:0034667 integrin alpha3-beta1 complex(GO:0034667)
0.1 1.5 GO:0031045 dense core granule(GO:0031045)
0.1 1.1 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.1 0.6 GO:0070695 FHF complex(GO:0070695)
0.1 2.1 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 0.7 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.1 0.9 GO:0001533 cornified envelope(GO:0001533)
0.1 2.8 GO:0060077 inhibitory synapse(GO:0060077)
0.1 0.6 GO:0033093 Weibel-Palade body(GO:0033093)
0.1 0.2 GO:0035339 SPOTS complex(GO:0035339)
0.1 0.8 GO:0045179 apical cortex(GO:0045179)
0.1 0.3 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.1 1.0 GO:0035102 PRC1 complex(GO:0035102)
0.1 0.6 GO:0048500 signal recognition particle(GO:0048500)
0.0 0.1 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.0 0.2 GO:0090498 extrinsic component of Golgi membrane(GO:0090498)
0.0 0.4 GO:0045098 type III intermediate filament(GO:0045098)
0.0 0.1 GO:0060205 secretory granule lumen(GO:0034774) cytoplasmic membrane-bounded vesicle lumen(GO:0060205)
0.0 0.3 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.6 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 0.1 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.0 0.6 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0 0.3 GO:0033269 internode region of axon(GO:0033269)
0.0 0.9 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 0.4 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 0.2 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.5 GO:0043218 compact myelin(GO:0043218)
0.0 1.1 GO:0030673 axolemma(GO:0030673)
0.0 0.1 GO:1990745 EARP complex(GO:1990745)
0.0 0.6 GO:0042588 zymogen granule(GO:0042588)
0.0 0.1 GO:0020018 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.0 0.4 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.3 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 0.2 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.1 GO:0033263 CORVET complex(GO:0033263)
0.0 0.3 GO:0044232 organelle membrane contact site(GO:0044232)
0.0 0.3 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.3 GO:0044294 dendritic growth cone(GO:0044294)
0.0 0.6 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.4 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.2 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.0 GO:0032585 multivesicular body membrane(GO:0032585)
0.0 0.1 GO:0000818 nuclear MIS12/MIND complex(GO:0000818)
0.0 0.1 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 0.1 GO:0099524 region of cytosol(GO:0099522) postsynaptic cytosol(GO:0099524)
0.0 0.1 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.0 0.3 GO:0045095 keratin filament(GO:0045095)
0.0 1.5 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 0.3 GO:0043196 varicosity(GO:0043196)
0.0 0.2 GO:0032279 asymmetric synapse(GO:0032279)
0.0 0.8 GO:0031985 Golgi cisterna(GO:0031985)
0.0 0.1 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.0 GO:0008091 spectrin(GO:0008091)
0.0 0.1 GO:0005861 troponin complex(GO:0005861)
0.0 1.2 GO:0016363 nuclear matrix(GO:0016363)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.0 GO:0031708 endothelin B receptor binding(GO:0031708)
0.4 2.8 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.3 0.9 GO:0030280 structural constituent of epidermis(GO:0030280)
0.3 1.2 GO:0050436 microfibril binding(GO:0050436)
0.2 0.9 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.2 0.6 GO:0050253 sterol esterase activity(GO:0004771) retinyl-palmitate esterase activity(GO:0050253)
0.2 0.8 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.2 0.6 GO:0070737 protein-glycine ligase activity, elongating(GO:0070737)
0.2 0.7 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.2 1.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.2 0.7 GO:0030348 syntaxin-3 binding(GO:0030348)
0.2 0.5 GO:0048030 disaccharide binding(GO:0048030)
0.2 0.8 GO:0004994 somatostatin receptor activity(GO:0004994)
0.2 2.4 GO:0005243 gap junction channel activity(GO:0005243)
0.1 0.4 GO:0009041 uridylate kinase activity(GO:0009041)
0.1 0.9 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.1 1.0 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1 0.4 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.1 0.4 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.1 0.7 GO:0035184 histone threonine kinase activity(GO:0035184)
0.1 0.6 GO:0032810 sterol response element binding(GO:0032810)
0.1 0.9 GO:0032051 clathrin light chain binding(GO:0032051)
0.1 0.3 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.1 0.3 GO:0019863 IgE binding(GO:0019863)
0.1 0.8 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.1 0.6 GO:0045340 mercury ion binding(GO:0045340)
0.1 0.5 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.1 0.4 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.1 0.2 GO:2001069 glycogen binding(GO:2001069)
0.1 0.3 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.1 2.1 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 0.2 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.1 0.4 GO:1902282 phosphorelay sensor kinase activity(GO:0000155) voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282)
0.1 0.6 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.1 0.2 GO:0038100 nodal binding(GO:0038100)
0.1 0.3 GO:1904288 BAT3 complex binding(GO:1904288)
0.1 0.2 GO:0045159 myosin II binding(GO:0045159)
0.1 0.4 GO:0004065 arylsulfatase activity(GO:0004065)
0.1 0.5 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.1 0.5 GO:0045545 syndecan binding(GO:0045545)
0.1 0.4 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.1 0.2 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.1 0.3 GO:0070320 inward rectifier potassium channel inhibitor activity(GO:0070320)
0.1 0.2 GO:0005171 hepatocyte growth factor receptor binding(GO:0005171)
0.1 0.3 GO:0032027 myosin light chain binding(GO:0032027)
0.1 1.5 GO:1900750 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.1 0.2 GO:0001888 glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0001888)
0.1 0.4 GO:0009374 biotin binding(GO:0009374)
0.1 0.3 GO:0047276 N-acetyllactosaminide 3-alpha-galactosyltransferase activity(GO:0047276)
0.1 0.4 GO:0033691 sialic acid binding(GO:0033691)
0.0 1.0 GO:0098641 cadherin binding involved in cell-cell adhesion(GO:0098641)
0.0 0.2 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.0 0.1 GO:0015222 serotonin transmembrane transporter activity(GO:0015222)
0.0 0.6 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 2.1 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.4 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.1 GO:0042015 interleukin-20 binding(GO:0042015)
0.0 0.9 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.3 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.6 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.2 GO:1902379 chemoattractant activity involved in axon guidance(GO:1902379)
0.0 0.2 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.0 0.2 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 1.3 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.1 GO:0050252 retinol O-fatty-acyltransferase activity(GO:0050252)
0.0 0.3 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 2.0 GO:0070888 E-box binding(GO:0070888)
0.0 0.1 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.5 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.2 GO:0004111 creatine kinase activity(GO:0004111)
0.0 1.3 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 0.3 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.0 0.3 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0 0.2 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.0 0.3 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.2 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064) L-lysine transmembrane transporter activity(GO:0015189)
0.0 0.5 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.1 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.1 GO:0004792 thiosulfate sulfurtransferase activity(GO:0004792)
0.0 0.9 GO:0032183 SUMO binding(GO:0032183)
0.0 0.5 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.2 GO:1990380 Lys63-specific deubiquitinase activity(GO:0061578) Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.3 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.1 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0 0.2 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.7 GO:0071837 HMG box domain binding(GO:0071837)
0.0 1.6 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.3 GO:0015250 water channel activity(GO:0015250)
0.0 0.3 GO:0051371 muscle alpha-actinin binding(GO:0051371)
0.0 0.1 GO:0031014 troponin T binding(GO:0031014)
0.0 0.1 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715) amidine-lyase activity(GO:0016842)
0.0 4.8 GO:0008236 serine-type peptidase activity(GO:0008236)
0.0 1.4 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.2 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.3 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.4 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.0 0.1 GO:0035877 death effector domain binding(GO:0035877)
0.0 0.1 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.1 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.3 GO:0043495 protein anchor(GO:0043495)
0.0 0.3 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.0 0.2 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.1 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.1 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.0 0.2 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0 0.3 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.6 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.1 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.0 0.3 GO:0060229 phospholipase activator activity(GO:0016004) lipase activator activity(GO:0060229)
0.0 2.2 GO:0005178 integrin binding(GO:0005178)
0.0 0.1 GO:0071253 connexin binding(GO:0071253)
0.0 0.2 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.5 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.1 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.0 0.2 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.1 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 1.3 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.0 0.3 GO:0019215 intermediate filament binding(GO:0019215)
0.0 0.4 GO:0005267 potassium channel activity(GO:0005267)
0.0 0.2 GO:0016208 AMP binding(GO:0016208)
0.0 0.5 GO:0008378 galactosyltransferase activity(GO:0008378)
0.0 0.6 GO:0043531 ADP binding(GO:0043531)
0.0 0.2 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.1 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.0 0.4 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 1.2 GO:0020037 heme binding(GO:0020037)
0.0 0.5 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.3 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 0.2 GO:0015245 fatty acid transporter activity(GO:0015245)
0.0 0.1 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.0 0.2 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
0.0 0.3 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.2 GO:0031005 filamin binding(GO:0031005)
0.0 0.5 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.9 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 1.9 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.5 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.7 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.4 PID FGF PATHWAY FGF signaling pathway
0.0 2.7 PID ENDOTHELIN PATHWAY Endothelins
0.0 1.9 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.6 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.5 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.8 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.4 PID IGF1 PATHWAY IGF1 pathway
0.0 0.4 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.6 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.3 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.3 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.8 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 0.6 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 0.1 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.2 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.3 PID IL23 PATHWAY IL23-mediated signaling events
0.0 0.8 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.3 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.6 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 1.1 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 0.5 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 0.6 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.4 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 0.2 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.3 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.3 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 2.6 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.4 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.2 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.4 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 0.1 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.2 PID BCR 5PATHWAY BCR signaling pathway
0.0 0.4 PID ERBB4 PATHWAY ErbB4 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.5 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.1 2.4 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.1 0.7 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.1 0.6 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.1 1.0 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.0 0.6 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.4 REACTOME ACTIVATED POINT MUTANTS OF FGFR2 Genes involved in Activated point mutants of FGFR2
0.0 0.6 REACTOME SIGNALING BY ACTIVATED POINT MUTANTS OF FGFR1 Genes involved in Signaling by activated point mutants of FGFR1
0.0 1.7 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.7 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.4 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 1.3 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 1.8 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.2 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 1.1 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.3 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.7 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 0.2 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.3 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.2 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 2.8 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.5 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.9 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.2 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.4 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.2 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.1 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.6 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.5 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.1 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 1.0 REACTOME AQUAPORIN MEDIATED TRANSPORT Genes involved in Aquaporin-mediated transport
0.0 0.1 REACTOME DEFENSINS Genes involved in Defensins
0.0 0.2 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.1 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.5 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.3 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism