Project

2D miR_HR1_12

Navigation
Downloads

Results for Alx4

Z-value: 0.67

Motif logo

Transcription factors associated with Alx4

Gene Symbol Gene ID Gene Info
ENSMUSG00000040310.6 aristaless-like homeobox 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Alx4mm10_v2_chr2_+_93642307_936423880.501.0e-01Click!

Activity profile of Alx4 motif

Sorted Z-values of Alx4 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr13_-_100786402 2.20 ENSMUST00000174038.1
ENSMUST00000091295.7
ENSMUST00000072119.8
cyclin B1
chr8_-_4779513 1.85 ENSMUST00000022945.7
Shc SH2-domain binding protein 1
chr5_-_138170992 1.29 ENSMUST00000139983.1
minichromosome maintenance deficient 7 (S. cerevisiae)
chr11_+_58171648 1.16 ENSMUST00000020820.1
mitochondrial ribosomal protein L22
chr13_+_104229366 1.09 ENSMUST00000022227.6
centromere protein K
chr5_-_138171248 0.96 ENSMUST00000153867.1
minichromosome maintenance deficient 7 (S. cerevisiae)
chr14_+_3825596 0.78 ENSMUST00000178256.1
predicted gene 3002
chr17_-_48432723 0.78 ENSMUST00000046549.3
apolipoprotein B mRNA editing enzyme, catalytic polypeptide 2
chr12_-_11265768 0.76 ENSMUST00000166117.1
Gen homolog 1, endonuclease (Drosophila)
chr2_+_163506808 0.74 ENSMUST00000143911.1
hepatic nuclear factor 4, alpha
chr14_+_5164535 0.73 ENSMUST00000179659.1
predicted gene 3317
chr7_+_45621805 0.73 ENSMUST00000033100.4
izumo sperm-egg fusion 1
chr14_+_3667518 0.72 ENSMUST00000112801.3
predicted gene 3020
chr2_+_65620829 0.72 ENSMUST00000028377.7
sodium channel, voltage-gated, type II, alpha 1
chr14_+_5517172 0.70 ENSMUST00000178220.1
predicted gene, 3488
chr14_-_6266620 0.69 ENSMUST00000096172.5
predicted gene 3411
chr1_+_161070767 0.68 ENSMUST00000111618.1
ENSMUST00000111620.3
ENSMUST00000028035.7
centromere protein L
chr14_+_4871156 0.65 ENSMUST00000166410.2
predicted gene 3264
chr10_-_128626464 0.65 ENSMUST00000026420.5
ribosomal protein S26
chr14_+_73138755 0.64 ENSMUST00000171070.1
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
chr6_-_148946146 0.63 ENSMUST00000132696.1
family with sequence similarity 60, member A
chr14_+_4430992 0.62 ENSMUST00000164603.1
ENSMUST00000166848.1
predicted gene 3173
chr8_+_46010596 0.62 ENSMUST00000110381.2
Lrp2 binding protein
chr4_+_122995944 0.59 ENSMUST00000106252.2
v-myc myelocytomatosis viral oncogene homolog, lung carcinoma derived (avian)
chrX_-_134111852 0.59 ENSMUST00000033610.6
NADPH oxidase 1
chr14_+_4514758 0.59 ENSMUST00000112776.2
predicted gene 3173
chr5_-_138171216 0.54 ENSMUST00000147920.1
minichromosome maintenance deficient 7 (S. cerevisiae)
chr14_+_3225315 0.54 ENSMUST00000178670.1
RIKEN cDNA D830030K20 gene
chr9_-_20959785 0.53 ENSMUST00000177754.1
DNA methyltransferase (cytosine-5) 1
chr4_+_122996035 0.53 ENSMUST00000030407.7
v-myc myelocytomatosis viral oncogene homolog, lung carcinoma derived (avian)
chr19_+_23723279 0.53 ENSMUST00000067077.1
predicted gene 9938
chr3_+_94372794 0.53 ENSMUST00000029795.3
RAR-related orphan receptor gamma
chr14_-_99099701 0.52 ENSMUST00000042471.9
DIS3 mitotic control homolog (S. cerevisiae)
chr11_-_106314494 0.52 ENSMUST00000167143.1
CD79B antigen
chr14_+_3224440 0.48 ENSMUST00000112797.4
RIKEN cDNA D830030K20 gene
chr14_-_6741430 0.48 ENSMUST00000100904.4
predicted gene 3636
chr10_-_80998174 0.48 ENSMUST00000118465.1
guanine nucleotide binding protein (G protein), gamma 7
chr10_-_67912620 0.47 ENSMUST00000064656.7
zinc finger protein 365
chr18_+_4920509 0.46 ENSMUST00000126977.1
supervillin
chr14_+_4023941 0.45 ENSMUST00000096184.4
predicted gene 5796
chr6_-_87335758 0.45 ENSMUST00000042025.9
anthrax toxin receptor 1
chr4_+_108719649 0.45 ENSMUST00000178992.1
RIKEN cDNA 3110021N24 gene
chr1_-_88277510 0.44 ENSMUST00000065420.5
ENSMUST00000054674.8
Holliday junction recognition protein
chr1_-_161070613 0.43 ENSMUST00000035430.3
aspartyl-tRNA synthetase 2 (mitochondrial)
chr2_+_125068118 0.43 ENSMUST00000070353.3
solute carrier family 24, member 5
chr6_+_122513583 0.43 ENSMUST00000032210.7
ENSMUST00000148517.1
microfibrillar associated protein 5
chr4_+_136172367 0.42 ENSMUST00000061721.5
E2F transcription factor 2
chr14_+_3846245 0.41 ENSMUST00000180934.1
predicted gene 3033
chr2_-_73453918 0.40 ENSMUST00000102679.1
WAS/WASL interacting protein family, member 1
chr7_+_101896817 0.39 ENSMUST00000143835.1
anaphase prompoting complex C subunit 15
chr2_+_71389239 0.39 ENSMUST00000028408.2
histone aminotransferase 1
chr5_-_91402905 0.39 ENSMUST00000121044.2
betacellulin, epidermal growth factor family member
chr4_+_95557494 0.38 ENSMUST00000079223.4
ENSMUST00000177394.1
FGGY carbohydrate kinase domain containing
chr15_-_9140374 0.36 ENSMUST00000096482.3
ENSMUST00000110585.2
S-phase kinase-associated protein 2 (p45)
chr1_+_93685574 0.36 ENSMUST00000027499.6
BCL2-related ovarian killer protein
chr11_-_4095344 0.36 ENSMUST00000004868.5
mitochondrial fission process 1
chr11_-_87359011 0.36 ENSMUST00000055438.4
protein phosphatase 1E (PP2C domain containing)
chr14_-_68533689 0.35 ENSMUST00000022640.7
a disintegrin and metallopeptidase domain 7
chr19_-_34475135 0.34 ENSMUST00000050562.4
cholesterol 25-hydroxylase
chrX_+_56787701 0.34 ENSMUST00000151033.1
four and a half LIM domains 1
chr2_-_17460610 0.34 ENSMUST00000145492.1
nebulette
chr1_-_24612700 0.34 ENSMUST00000088336.1
predicted gene 10222
chr9_-_123678782 0.33 ENSMUST00000170591.1
ENSMUST00000171647.1
solute carrier family 6 (neurotransmitter transporter), member 20A
chr13_-_58354862 0.33 ENSMUST00000043605.5
kinesin family member 27
chr5_-_151651216 0.33 ENSMUST00000038131.9
replication factor C (activator 1) 3
chr9_-_78480736 0.33 ENSMUST00000156988.1
eukaryotic translation elongation factor 1 alpha 1
chr1_-_152386675 0.33 ENSMUST00000015124.8
tRNA splicing endonuclease 15 homolog (S. cerevisiae)
chrM_+_9452 0.33 ENSMUST00000082411.1
mitochondrially encoded NADH dehydrogenase 3
chr19_-_41933276 0.33 ENSMUST00000075280.4
ENSMUST00000112123.2
exosome component 1
chr5_+_104202609 0.32 ENSMUST00000066708.5
dentin matrix protein 1
chr4_-_70410422 0.32 ENSMUST00000144099.1
CDK5 regulatory subunit associated protein 2
chr12_-_79190955 0.31 ENSMUST00000085254.6
retinol dehydrogenase 11
chrM_+_9870 0.31 ENSMUST00000084013.1
mitochondrially encoded NADH dehydrogenase 4L
chr8_-_70510322 0.31 ENSMUST00000140679.1
ENSMUST00000129909.1
ENSMUST00000081940.4
ubiquitin A-52 residue ribosomal protein fusion product 1
chr19_+_8735808 0.30 ENSMUST00000049424.9
WD repeat domain 74
chr13_-_81710937 0.30 ENSMUST00000161920.1
ENSMUST00000048993.5
polymerase (RNA) III (DNA directed) polypeptide G
chrM_+_2743 0.29 ENSMUST00000082392.1
mitochondrially encoded NADH dehydrogenase 1
chr5_+_121397936 0.29 ENSMUST00000042163.8
N(alpha)-acetyltransferase 25, NatB auxiliary subunit
chr1_-_180199587 0.29 ENSMUST00000161743.1
aarF domain containing kinase 3
chr18_+_46597698 0.28 ENSMUST00000078079.3
ENSMUST00000168382.1
eukaryotic translation initiation factor 1A
chr14_+_24490678 0.28 ENSMUST00000169826.1
ENSMUST00000112384.3
ribosomal protein S24
chr7_+_101896340 0.28 ENSMUST00000035395.7
ENSMUST00000106973.1
ENSMUST00000144207.1
anaphase prompoting complex C subunit 15
chr11_+_98026695 0.28 ENSMUST00000092425.4
ribosomal protein L19
chr1_-_133610253 0.28 ENSMUST00000166915.1
small nuclear ribonucleoprotein E
chr16_-_45724600 0.28 ENSMUST00000096057.4
transgelin 3
chr4_+_146502027 0.28 ENSMUST00000105735.2
predicted gene 13247
chr7_-_45204892 0.27 ENSMUST00000121017.2
coiled-coil domain containing 155
chr12_-_113361232 0.27 ENSMUST00000103423.1
Immunoglobulin heavy constant gamma 3
chr1_+_156558759 0.27 ENSMUST00000173929.1
v-abl Abelson murine leukemia viral oncogene 2 (arg, Abelson-related gene)
chrM_+_11734 0.27 ENSMUST00000082418.1
mitochondrially encoded NADH dehydrogenase 5
chr5_-_149053038 0.26 ENSMUST00000085546.6
high mobility group box 1
chr5_-_150518164 0.26 ENSMUST00000118769.1
zygote arrest 1-like
chr1_-_152386589 0.25 ENSMUST00000162371.1
tRNA splicing endonuclease 15 homolog (S. cerevisiae)
chr8_+_84689247 0.25 ENSMUST00000109767.2
ENSMUST00000177084.1
ENSMUST00000109768.2
ENSMUST00000152301.2
ENSMUST00000177423.1
tRNA methyltransferase 1
chr7_+_28808795 0.25 ENSMUST00000172529.1
heterogeneous nuclear ribonucleoprotein L
chr11_+_98026918 0.25 ENSMUST00000017548.6
ribosomal protein L19
chr7_-_25005895 0.25 ENSMUST00000102858.3
ENSMUST00000080882.6
ATPase, Na+/K+ transporting, alpha 3 polypeptide
chr5_-_137858034 0.24 ENSMUST00000110978.2
paired immunoglobin-like type 2 receptor beta 1
chr12_+_4769375 0.24 ENSMUST00000178879.1
profilin family, member 4
chr16_+_45224315 0.24 ENSMUST00000102802.3
ENSMUST00000063654.4
B and T lymphocyte associated
chr2_+_11705355 0.24 ENSMUST00000128156.2
interleukin 15 receptor, alpha chain
chr8_+_84689308 0.24 ENSMUST00000125370.3
ENSMUST00000175784.1
tRNA methyltransferase 1
chr6_+_122513676 0.24 ENSMUST00000142896.1
ENSMUST00000121656.1
microfibrillar associated protein 5
chr14_+_3428103 0.23 ENSMUST00000178060.1
predicted gene 3005
chr8_-_122915987 0.23 ENSMUST00000098333.4
ankyrin repeat domain 11
chr1_-_78488846 0.23 ENSMUST00000068333.7
ENSMUST00000170217.1
phenylalanyl-tRNA synthetase, beta subunit
chr7_+_3703979 0.23 ENSMUST00000006496.8
ribosomal protein S9
chr8_-_62123106 0.22 ENSMUST00000034052.6
ENSMUST00000034054.7
annexin A10
chr12_+_84361968 0.22 ENSMUST00000021661.6
coenzyme Q6 homolog (yeast)
chr5_-_63968867 0.21 ENSMUST00000154169.1
RELT-like 1
chr14_-_100149764 0.21 ENSMUST00000097079.4
Kruppel-like factor 12
chr13_-_54399246 0.20 ENSMUST00000124238.1
predicted gene 16248
chr9_+_102834961 0.20 ENSMUST00000035142.6
receptor-like tyrosine kinase
chr14_-_104522615 0.19 ENSMUST00000022716.2
ring finger protein 219
chrX_-_9256899 0.19 ENSMUST00000115553.2
predicted gene 14862
chr5_+_3543812 0.19 ENSMUST00000115527.3
family with sequence similarity 133, member B
chr19_-_32196393 0.19 ENSMUST00000151822.1
sphingomyelin synthase 1
chr19_-_10829921 0.19 ENSMUST00000039043.8
CD6 antigen
chr1_-_38821215 0.19 ENSMUST00000039612.4
LON peptidase N-terminal domain and ring finger 2
chr11_-_51606840 0.19 ENSMUST00000074669.3
ENSMUST00000101249.2
ENSMUST00000109103.3
heterogeneous nuclear ribonucleoprotein A/B
chr10_+_128337761 0.19 ENSMUST00000005826.7
citrate synthase
chr14_-_69707546 0.18 ENSMUST00000118374.1
R3H domain and coiled-coil containing 1
chr3_-_96452306 0.18 ENSMUST00000093126.4
ENSMUST00000098841.3
cDNA sequence BC107364
chrX_-_143933089 0.18 ENSMUST00000087313.3
doublecortin
chr7_+_30458280 0.18 ENSMUST00000126297.1
nephrosis 1, nephrin
chr5_+_121463150 0.18 ENSMUST00000156080.1
ENSMUST00000031405.5
ENSMUST00000094357.4
transmembrane protein 116
chr11_-_79962374 0.18 ENSMUST00000108241.1
ENSMUST00000043152.5
UTP6, small subunit (SSU) processome component, homolog (yeast)
chr19_-_10830045 0.18 ENSMUST00000080292.5
CD6 antigen
chr15_-_76229492 0.18 ENSMUST00000074834.5
plectin
chr14_-_69707493 0.17 ENSMUST00000121142.1
R3H domain and coiled-coil containing 1
chr19_+_41933464 0.17 ENSMUST00000026154.7
zinc finger, DHHC domain containing 16
chr7_+_12927410 0.17 ENSMUST00000045870.4
RIKEN cDNA 2310014L17 gene
chrX_+_136741821 0.17 ENSMUST00000089350.4
cDNA sequence BC065397
chr2_+_121956651 0.17 ENSMUST00000110574.1
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
chrM_+_8600 0.17 ENSMUST00000082409.1
mitochondrially encoded cytochrome c oxidase III
chr9_-_22259887 0.17 ENSMUST00000086281.4
zinc finger protein 599
chrX_+_134686519 0.17 ENSMUST00000124226.2
armadillo repeat containing, X-linked 4
chr2_+_144270900 0.16 ENSMUST00000028910.2
ENSMUST00000110027.1
mitochondrial genome maintainance exonuclease 1
chr17_-_15527281 0.16 ENSMUST00000154293.1
ENSMUST00000054450.6
programmed cell death 2
chr7_-_46667303 0.16 ENSMUST00000168335.1
tryptophan hydroxylase 1
chr11_-_11970540 0.16 ENSMUST00000109653.1
growth factor receptor bound protein 10
chr9_-_123678873 0.16 ENSMUST00000040960.6
solute carrier family 6 (neurotransmitter transporter), member 20A
chr2_-_73580288 0.16 ENSMUST00000028515.3
cholinergic receptor, nicotinic, alpha polypeptide 1 (muscle)
chr2_+_11705287 0.15 ENSMUST00000135341.1
ENSMUST00000138349.1
ENSMUST00000123600.2
interleukin 15 receptor, alpha chain
chr5_+_26817357 0.15 ENSMUST00000071500.6
dipeptidylpeptidase 6
chr4_+_43493345 0.15 ENSMUST00000030181.5
ENSMUST00000107922.2
coiled-coil domain containing 107
chr10_+_18845071 0.15 ENSMUST00000019998.7
PERP, TP53 apoptosis effector
chr6_-_87533219 0.15 ENSMUST00000113637.2
ENSMUST00000071024.6
Rho GTPase activating protein 25
chr11_-_80377975 0.15 ENSMUST00000179332.1
ENSMUST00000103225.4
ENSMUST00000134274.1
RIKEN cDNA 5730455P16 gene
chr13_+_90923122 0.15 ENSMUST00000051955.7
ribosomal protein S23
chr10_-_81407641 0.14 ENSMUST00000140916.1
nuclear factor I/C
chr4_-_150914401 0.14 ENSMUST00000105675.1
Parkinson disease (autosomal recessive, early onset) 7
chr6_+_122513643 0.14 ENSMUST00000118626.1
microfibrillar associated protein 5
chrM_+_7005 0.14 ENSMUST00000082405.1
mitochondrially encoded cytochrome c oxidase II
chr2_-_105017015 0.14 ENSMUST00000111110.2
ENSMUST00000028592.5
eukaryotic translation initiation factor 3, subunit M
chr12_-_80643799 0.14 ENSMUST00000166931.1
enhancer of rudimentary homolog (Drosophila)
chr19_-_10829856 0.13 ENSMUST00000174176.1
CD6 antigen
chr4_-_147702553 0.13 ENSMUST00000117638.1
zinc finger protein 534
chr5_+_115279666 0.13 ENSMUST00000040421.4
coenzyme Q5 homolog, methyltransferase (yeast)
chr18_-_56572888 0.13 ENSMUST00000174518.1
aldehyde dehydrogenase family 7, member A1
chr14_+_32321987 0.13 ENSMUST00000022480.7
oxoglutarate dehydrogenase-like
chr1_-_185329331 0.12 ENSMUST00000027921.4
ENSMUST00000110975.1
ENSMUST00000110974.3
isoleucine-tRNA synthetase 2, mitochondrial
chr17_-_34121944 0.12 ENSMUST00000151986.1
bromodomain containing 2
chr9_-_70934808 0.12 ENSMUST00000034731.8
lipase, hepatic
chr5_-_62766153 0.12 ENSMUST00000076623.4
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr4_-_43558386 0.12 ENSMUST00000130353.1
talin 1
chr17_-_34122311 0.11 ENSMUST00000025193.6
bromodomain containing 2
chr11_+_109543694 0.11 ENSMUST00000106696.1
arylsulfatase G
chr3_-_100489324 0.11 ENSMUST00000061455.8
family with sequence similarity 46, member C
chr9_+_92457369 0.11 ENSMUST00000034941.7
phospholipid scramblase 4
chrX_+_73483602 0.11 ENSMUST00000033741.8
ENSMUST00000169489.1
biglycan
chr10_-_78352469 0.11 ENSMUST00000138035.1
1-acylglycerol-3-phosphate O-acyltransferase 3
chr4_+_145514884 0.11 ENSMUST00000105741.1
predicted gene 13225
chr9_-_71163224 0.11 ENSMUST00000074465.2
aquaporin 9
chrX_+_16619698 0.11 ENSMUST00000026013.5
monoamine oxidase A
chr9_+_22475867 0.11 ENSMUST00000128812.1
Bardet-Biedl syndrome 9 (human)
chrX_+_9885622 0.10 ENSMUST00000067529.2
ENSMUST00000086165.3
synaptotagmin-like 5
chr14_-_24486994 0.10 ENSMUST00000026322.7
polymerase (RNA) III (DNA directed) polypeptide A
chr13_+_80886095 0.10 ENSMUST00000161441.1
arrestin domain containing 3
chr12_-_69893162 0.10 ENSMUST00000049239.7
ENSMUST00000110570.1
mitogen-activated protein kinase kinase kinase kinase 5
chr1_+_85575676 0.10 ENSMUST00000178024.1
RIKEN cDNA G530012D1 gene
chr19_-_8818924 0.09 ENSMUST00000153281.1
tetratricopeptide repeat domain 9C
chr4_+_146097312 0.09 ENSMUST00000105730.1
ENSMUST00000091878.5
predicted gene 13051
chr6_+_145934113 0.09 ENSMUST00000032383.7
sarcospan
chr1_-_138175126 0.09 ENSMUST00000183301.1
protein tyrosine phosphatase, receptor type, C
chr15_-_9529868 0.09 ENSMUST00000003981.4
interleukin 7 receptor
chr4_+_145510759 0.09 ENSMUST00000105742.1
ENSMUST00000136309.1
predicted gene 13225
chrM_+_10167 0.09 ENSMUST00000082414.1
mitochondrially encoded NADH dehydrogenase 4
chr16_+_18836573 0.09 ENSMUST00000055413.6
RIKEN cDNA 2510002D24 gene
chr12_+_16653470 0.09 ENSMUST00000111064.1
neurotensin receptor 2
chr6_+_124304646 0.09 ENSMUST00000112541.2
ENSMUST00000032234.2
CD163 antigen
chr12_+_30884321 0.08 ENSMUST00000067087.6
family with sequence similarity 150, member B
chr10_-_117148474 0.08 ENSMUST00000020381.3
fibroblast growth factor receptor substrate 2
chr14_+_26259109 0.08 ENSMUST00000174494.1
double homeobox B-like 3
chr5_-_84417359 0.08 ENSMUST00000113401.1
Eph receptor A5
chr18_-_36454487 0.08 ENSMUST00000025204.5
prefoldin 1
chr11_-_98193260 0.08 ENSMUST00000092735.5
ENSMUST00000107545.2
mediator complex subunit 1
chr1_+_60746358 0.08 ENSMUST00000027165.2
CD28 antigen
chr6_+_134640940 0.08 ENSMUST00000062755.8
loss of heterozygosity, 12, chromosomal region 1 homolog (human)
chr7_-_101581161 0.08 ENSMUST00000063920.2
ADP-ribosyltransferase 2b

Network of associatons between targets according to the STRING database.

First level regulatory network of Alx4

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.2 GO:0031660 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662)
0.3 2.8 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.2 0.7 GO:0010534 regulation of activation of JAK2 kinase activity(GO:0010534) activation of JAK2 kinase activity(GO:0042977) negative regulation of activation of JAK2 kinase activity(GO:1902569)
0.2 0.6 GO:0045726 positive regulation of integrin biosynthetic process(GO:0045726)
0.2 0.5 GO:0002940 tRNA N2-guanine methylation(GO:0002940)
0.2 0.5 GO:0033566 gamma-tubulin complex localization(GO:0033566)
0.1 0.5 GO:0090309 positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.1 0.5 GO:0071043 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.1 0.5 GO:0035524 proline transmembrane transport(GO:0035524)
0.1 0.4 GO:0048022 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.1 1.4 GO:1903504 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.1 0.2 GO:0036518 chemorepulsion of dopaminergic neuron axon(GO:0036518)
0.1 0.3 GO:0090172 microtubule cytoskeleton organization involved in homologous chromosome segregation(GO:0090172)
0.1 0.4 GO:0097360 chorionic trophoblast cell proliferation(GO:0097360) regulation of chorionic trophoblast cell proliferation(GO:1901382)
0.1 0.3 GO:0002270 plasmacytoid dendritic cell activation(GO:0002270) positive regulation of glycogen catabolic process(GO:0045819)
0.1 0.8 GO:0016554 cytidine to uridine editing(GO:0016554)
0.1 0.4 GO:0061641 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.1 0.3 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.1 0.7 GO:0045631 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.1 0.7 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.1 0.3 GO:0036367 adaptation of rhodopsin mediated signaling(GO:0016062) light adaption(GO:0036367)
0.1 0.3 GO:0090231 regulation of spindle checkpoint(GO:0090231)
0.1 0.4 GO:1990086 lens fiber cell apoptotic process(GO:1990086)
0.1 0.2 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.1 0.2 GO:0045903 positive regulation of translational fidelity(GO:0045903)
0.0 0.5 GO:0072615 interleukin-17 secretion(GO:0072615)
0.0 0.5 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.0 0.1 GO:1903185 glycolate metabolic process(GO:0009441) enzyme active site formation via L-cysteine sulfinic acid(GO:0018323) primary alcohol biosynthetic process(GO:0034309) cellular response to glyoxal(GO:0036471) glycolate biosynthetic process(GO:0046295) negative regulation of TRAIL-activated apoptotic signaling pathway(GO:1903122) regulation of pyrroline-5-carboxylate reductase activity(GO:1903167) positive regulation of pyrroline-5-carboxylate reductase activity(GO:1903168) regulation of tyrosine 3-monooxygenase activity(GO:1903176) positive regulation of tyrosine 3-monooxygenase activity(GO:1903178) L-dopa metabolic process(GO:1903184) L-dopa biosynthetic process(GO:1903185) glyoxal metabolic process(GO:1903189) regulation of L-dopa biosynthetic process(GO:1903195) positive regulation of L-dopa biosynthetic process(GO:1903197) regulation of L-dopa decarboxylase activity(GO:1903198) positive regulation of L-dopa decarboxylase activity(GO:1903200) positive regulation of cellular amino acid biosynthetic process(GO:2000284)
0.0 0.6 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.3 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.1 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
0.0 0.4 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.0 0.4 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.0 0.3 GO:0035754 B cell chemotaxis(GO:0035754)
0.0 0.3 GO:1900264 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.0 0.3 GO:0042427 serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162)
0.0 0.4 GO:0035810 positive regulation of urine volume(GO:0035810)
0.0 0.3 GO:0070170 regulation of tooth mineralization(GO:0070170)
0.0 0.4 GO:1905050 positive regulation of metallopeptidase activity(GO:1905050)
0.0 0.3 GO:1900042 positive regulation of interleukin-2 secretion(GO:1900042)
0.0 0.5 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.2 GO:0043504 mitochondrial DNA repair(GO:0043504)
0.0 0.1 GO:0015851 nucleobase transport(GO:0015851) pyrimidine nucleobase transport(GO:0015855)
0.0 0.8 GO:0097435 fibril organization(GO:0097435)
0.0 0.5 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.0 0.2 GO:1902416 positive regulation of mRNA binding(GO:1902416)
0.0 0.2 GO:0036376 sodium ion export from cell(GO:0036376)
0.0 0.1 GO:0090327 negative regulation of locomotion involved in locomotory behavior(GO:0090327)
0.0 0.2 GO:0046642 negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.0 0.4 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.4 GO:0006744 ubiquinone biosynthetic process(GO:0006744)
0.0 0.2 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.0 0.2 GO:1902035 positive regulation of hematopoietic stem cell proliferation(GO:1902035)
0.0 0.5 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 0.2 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.1 GO:0046619 optic placode formation involved in camera-type eye formation(GO:0046619)
0.0 0.1 GO:0042420 dopamine catabolic process(GO:0042420)
0.0 0.1 GO:0060488 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490) non-canonical Wnt signaling pathway involved in heart development(GO:0061341) planar cell polarity pathway involved in heart morphogenesis(GO:0061346)
0.0 0.4 GO:0032825 positive regulation of natural killer cell differentiation(GO:0032825)
0.0 1.6 GO:0008543 fibroblast growth factor receptor signaling pathway(GO:0008543)
0.0 0.0 GO:0060298 positive regulation of sarcomere organization(GO:0060298)
0.0 0.2 GO:0045719 negative regulation of glycogen biosynthetic process(GO:0045719)
0.0 0.1 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
0.0 0.7 GO:0033119 negative regulation of RNA splicing(GO:0033119)
0.0 0.1 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.1 GO:0042989 sequestering of actin monomers(GO:0042989)
0.0 0.2 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.1 GO:0034372 very-low-density lipoprotein particle remodeling(GO:0034372)
0.0 0.8 GO:0050853 B cell receptor signaling pathway(GO:0050853)
0.0 0.2 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.0 0.5 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 0.0 GO:0021506 anterior neuropore closure(GO:0021506) neuropore closure(GO:0021995)
0.0 0.7 GO:0042773 ATP synthesis coupled electron transport(GO:0042773)
0.0 0.2 GO:0006107 oxaloacetate metabolic process(GO:0006107)
0.0 0.1 GO:0097186 amelogenesis(GO:0097186)
0.0 0.1 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.2 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.2 2.8 GO:0042555 MCM complex(GO:0042555)
0.1 0.2 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.1 0.8 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.1 0.5 GO:0019815 B cell receptor complex(GO:0019815)
0.1 0.6 GO:0043020 NADPH oxidase complex(GO:0043020)
0.1 0.3 GO:0005663 DNA replication factor C complex(GO:0005663)
0.1 0.5 GO:0089717 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.0 0.8 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.4 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.2 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.3 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.2 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 0.6 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.3 GO:0019814 immunoglobulin complex(GO:0019814)
0.0 0.1 GO:0034709 methylosome(GO:0034709)
0.0 0.7 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.7 GO:0002080 acrosomal membrane(GO:0002080)
0.0 1.3 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.3 GO:0005687 U4 snRNP(GO:0005687)
0.0 0.3 GO:0031414 N-terminal protein acetyltransferase complex(GO:0031414)
0.0 0.0 GO:0042585 germinal vesicle(GO:0042585)
0.0 1.2 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.9 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.2 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.4 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.4 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.1 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 0.4 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.0 0.1 GO:0060187 cell pole(GO:0060187)
0.0 0.2 GO:0045120 pronucleus(GO:0045120)
0.0 0.5 GO:0070469 respiratory chain(GO:0070469)
0.0 0.4 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 0.8 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.1 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 0.2 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.4 GO:0035145 exon-exon junction complex(GO:0035145)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.2 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.2 0.7 GO:0070540 stearic acid binding(GO:0070540)
0.2 0.8 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.1 0.6 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.1 0.8 GO:0004126 cytidine deaminase activity(GO:0004126)
0.1 0.8 GO:1990932 5.8S rRNA binding(GO:1990932)
0.1 0.4 GO:0019150 D-ribulokinase activity(GO:0019150)
0.1 0.4 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.1 0.5 GO:0008142 oxysterol binding(GO:0008142)
0.1 0.5 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.1 0.6 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.1 0.8 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.1 0.3 GO:0000401 open form four-way junction DNA binding(GO:0000401) crossed form four-way junction DNA binding(GO:0000402)
0.1 0.7 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.1 0.3 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
0.1 2.8 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.1 0.5 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.1 0.5 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.0 0.5 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.0 0.1 GO:0036470 tyrosine 3-monooxygenase activator activity(GO:0036470) L-dopa decarboxylase activator activity(GO:0036478)
0.0 0.2 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.3 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 1.3 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.1 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
0.0 0.2 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 1.8 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.1 GO:0008802 betaine-aldehyde dehydrogenase activity(GO:0008802)
0.0 0.3 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.3 GO:1990446 U1 snRNP binding(GO:1990446)
0.0 0.2 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.3 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.3 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.0 0.3 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.2 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.2 GO:0008297 single-stranded DNA exodeoxyribonuclease activity(GO:0008297)
0.0 0.4 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.0 0.1 GO:0015254 purine nucleobase transmembrane transporter activity(GO:0005345) pyrimidine nucleobase transmembrane transporter activity(GO:0005350) nucleobase transmembrane transporter activity(GO:0015205) glycerol channel activity(GO:0015254)
0.0 0.1 GO:0036033 mediator complex binding(GO:0036033)
0.0 0.4 GO:0051400 BH domain binding(GO:0051400)
0.0 0.1 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 0.1 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0 0.5 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.0 0.3 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.1 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 2.2 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.0 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.3 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.2 GO:0042166 acetylcholine-gated cation channel activity(GO:0022848) acetylcholine binding(GO:0042166)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.1 PID ATR PATHWAY ATR signaling pathway
0.1 2.6 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.1 0.4 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.4 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.1 PID ERBB1 RECEPTOR PROXIMAL PATHWAY EGF receptor (ErbB1) signaling pathway
0.0 0.2 PID ERBB2 ERBB3 PATHWAY ErbB2/ErbB3 signaling events
0.0 0.7 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.2 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.2 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.2 2.8 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.1 0.4 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.1 0.8 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.1 0.3 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
0.0 1.5 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.3 REACTOME POL SWITCHING Genes involved in Polymerase switching
0.0 1.3 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.3 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 0.5 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.6 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.3 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.3 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.4 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 0.2 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.5 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 0.1 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.5 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.9 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.2 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.1 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.1 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.0 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.0 0.1 REACTOME PROLONGED ERK ACTIVATION EVENTS Genes involved in Prolonged ERK activation events