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2D miR_HR1_12

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Results for Nr2c1

Z-value: 0.42

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Transcription factors associated with Nr2c1

Gene Symbol Gene ID Gene Info
ENSMUSG00000005897.8 nuclear receptor subfamily 2, group C, member 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Nr2c1mm10_v2_chr10_+_94147982_941480230.264.2e-01Click!

Activity profile of Nr2c1 motif

Sorted Z-values of Nr2c1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr7_+_140093388 0.60 ENSMUST00000026540.8
proline-rich acidic protein 1
chr6_+_71199827 0.60 ENSMUST00000067492.7
fatty acid binding protein 1, liver
chr14_+_75136475 0.35 ENSMUST00000122840.1
lymphocyte cytosolic protein 1
chr8_-_122460666 0.31 ENSMUST00000006762.5
snail homolog 3 (Drosophila)
chr9_-_21037775 0.30 ENSMUST00000180870.1
predicted gene, 26592
chr16_-_4523056 0.29 ENSMUST00000090500.3
ENSMUST00000023161.7
sarcalumenin
chr3_+_32529532 0.29 ENSMUST00000147350.1
mitofusin 1
chr15_-_76209056 0.26 ENSMUST00000071869.5
ENSMUST00000170915.1
plectin
chr15_-_81408261 0.24 ENSMUST00000057236.3
DnaJ (Hsp40) homolog, subfamily B, member 7
chr10_+_127705170 0.24 ENSMUST00000079590.5
myosin IA
chr17_+_35194502 0.23 ENSMUST00000173600.1
lymphotoxin B
chr2_+_22895583 0.23 ENSMUST00000152170.1
prenyl (solanesyl) diphosphate synthase, subunit 1
chr3_-_32365608 0.22 ENSMUST00000168566.1
zinc finger matrin type 3
chr17_-_8101228 0.21 ENSMUST00000097422.4
predicted gene 1604A
chr2_+_22895482 0.20 ENSMUST00000053729.7
prenyl (solanesyl) diphosphate synthase, subunit 1
chr7_+_30493622 0.20 ENSMUST00000058280.6
ENSMUST00000133318.1
ENSMUST00000142575.1
ENSMUST00000131040.1
proline dehydrogenase (oxidase) 2
chr3_-_32365643 0.20 ENSMUST00000029199.5
zinc finger matrin type 3
chr9_-_29411736 0.18 ENSMUST00000115236.1
neurotrimin
chr11_+_3488275 0.18 ENSMUST00000064265.6
phospholipase A2, group III
chr7_+_82648595 0.17 ENSMUST00000141726.1
ENSMUST00000179489.1
ENSMUST00000039881.3
elongation factor Tu GTP binding domain containing 1
chr3_-_115888086 0.17 ENSMUST00000067500.5
RIKEN cDNA A930005H10 gene
chr15_-_89425795 0.16 ENSMUST00000168376.1
carnitine palmitoyltransferase 1b, muscle
chr1_-_120120138 0.16 ENSMUST00000112648.1
ENSMUST00000128408.1
diazepam binding inhibitor
chr15_+_79141324 0.16 ENSMUST00000040077.6
polymerase (RNA) II (DNA directed) polypeptide F
chr3_+_58526303 0.16 ENSMUST00000138848.1
eukaryotic translation initiation factor 2A
chr10_-_93589621 0.15 ENSMUST00000020203.6
small nuclear ribonucleoprotein polypeptide F
chr15_+_25773985 0.15 ENSMUST00000125667.1
myosin X
chr13_-_73328442 0.15 ENSMUST00000022097.5
NADH dehydrogenase (ubiquinone) Fe-S protein 6
chr5_-_137072254 0.14 ENSMUST00000077523.3
ENSMUST00000041388.4
serine (or cysteine) peptidase inhibitor, clade E, member 1
chrX_+_100729917 0.14 ENSMUST00000019503.7
glycerophosphodiester phosphodiesterase domain containing 2
chr3_+_96830069 0.13 ENSMUST00000058865.7
PDZ domain containing 1
chr9_-_106158109 0.13 ENSMUST00000159809.1
ENSMUST00000162562.1
ENSMUST00000036382.6
ENSMUST00000112543.2
glycerate kinase
chr9_-_50659780 0.13 ENSMUST00000034567.3
dihydrolipoamide S-acetyltransferase (E2 component of pyruvate dehydrogenase complex)
chr1_+_93215899 0.12 ENSMUST00000138595.1
RIKEN cDNA E030010N08 gene
chr1_-_167285110 0.12 ENSMUST00000027839.8
uridine-cytidine kinase 2
chr19_+_10937154 0.11 ENSMUST00000037261.3
G protein-coupled receptor 44
chr9_-_29412204 0.11 ENSMUST00000115237.1
neurotrimin
chr1_+_166254095 0.11 ENSMUST00000111416.1
immunoglobulin-like domain containing receptor 2
chr13_+_44729794 0.11 ENSMUST00000172830.1
jumonji, AT rich interactive domain 2
chr4_-_11076160 0.11 ENSMUST00000058183.8
NADH dehydrogenase (ubiquinone) complex I, assembly factor 6
chr16_+_44139821 0.11 ENSMUST00000159514.1
ENSMUST00000161326.1
ENSMUST00000063520.8
ENSMUST00000063542.7
N(alpha)-acetyltransferase 50, NatE catalytic subunit
chr4_+_127172866 0.11 ENSMUST00000106094.2
discs, large (Drosophila) homolog-associated protein 3
chr7_+_46397648 0.11 ENSMUST00000160433.1
potassium voltage gated channel, Shaw-related subfamily, member 1
chr7_-_31115227 0.11 ENSMUST00000168884.1
ENSMUST00000108102.2
hepsin
chr10_+_93589413 0.10 ENSMUST00000181835.1
RIKEN cDNA 4933408J17 gene
chr15_-_102366314 0.10 ENSMUST00000078508.5
Sp7 transcription factor 7
chr14_+_50924968 0.10 ENSMUST00000049411.5
ENSMUST00000136753.1
ENSMUST00000154288.1
apurinic/apyrimidinic endonuclease 1
chr15_-_98093245 0.10 ENSMUST00000180657.1
SUMO1/sentrin specific peptidase 1
chr1_-_155417283 0.10 ENSMUST00000027741.5
xenotropic and polytropic retrovirus receptor 1
chrX_-_102189371 0.09 ENSMUST00000033683.7
ribosomal protein S4, X-linked
chr14_+_75136326 0.09 ENSMUST00000145303.1
lymphocyte cytosolic protein 1
chr4_+_137993016 0.09 ENSMUST00000105830.2
ENSMUST00000084215.5
ENSMUST00000058133.3
ENSMUST00000139759.1
eukaryotic translation initiation factor 4 gamma, 3
chr2_-_62573813 0.09 ENSMUST00000174234.1
ENSMUST00000000402.9
ENSMUST00000174448.1
fibroblast activation protein
chr2_+_144823666 0.09 ENSMUST00000028918.2
SCP2 sterol-binding domain containing 1
chr4_-_82859571 0.09 ENSMUST00000156055.1
ENSMUST00000030110.8
zinc finger, DHHC domain containing 21
chr3_+_68572245 0.08 ENSMUST00000170788.2
schwannomin interacting protein 1
chr2_+_79707780 0.08 ENSMUST00000090760.2
ENSMUST00000040863.4
ENSMUST00000111780.2
protein phosphatase 1, regulatory (inhibitor) subunit 1C
chr3_+_58525821 0.08 ENSMUST00000029387.8
eukaryotic translation initiation factor 2A
chr11_-_76577701 0.07 ENSMUST00000176179.1
active BCR-related gene
chr6_-_83054415 0.07 ENSMUST00000113962.1
ENSMUST00000089645.6
ENSMUST00000113963.1
HtrA serine peptidase 2
chr15_+_3270767 0.07 ENSMUST00000082424.4
ENSMUST00000159158.1
ENSMUST00000159216.1
ENSMUST00000160311.1
selenoprotein P, plasma, 1
chr4_+_118429701 0.07 ENSMUST00000067896.3
elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 1
chr2_-_62573905 0.07 ENSMUST00000102732.3
fibroblast activation protein
chr17_+_75465538 0.07 ENSMUST00000095204.4
RAS, guanyl releasing protein 3
chr1_-_74544275 0.07 ENSMUST00000044260.4
ubiquitin specific peptidase 37
chr1_-_120120937 0.07 ENSMUST00000151708.1
diazepam binding inhibitor
chr5_+_105519388 0.06 ENSMUST00000067924.6
ENSMUST00000150981.1
leucine rich repeat containing 8 family, member C
chr4_-_117251879 0.06 ENSMUST00000165128.1
ENSMUST00000077500.4
predicted gene 1661
chr2_-_104742802 0.06 ENSMUST00000028595.7
DEP domain containing 7
chr10_+_13008442 0.06 ENSMUST00000105139.3
splicing factor 3b, subunit 5
chr2_+_164805082 0.06 ENSMUST00000052107.4
zinc finger SWIM-type containing 3
chr7_+_110768169 0.06 ENSMUST00000170374.1
adenosine monophosphate deaminase 3
chr15_+_80091320 0.06 ENSMUST00000009728.6
ENSMUST00000009727.5
synaptogyrin 1
chr1_-_58973421 0.06 ENSMUST00000173590.1
ENSMUST00000027186.5
trafficking protein, kinesin binding 2
chr5_-_5265224 0.05 ENSMUST00000115450.1
cyclin-dependent kinase 14
chr2_-_129048172 0.05 ENSMUST00000145798.2
predicted gene 14025
chr15_+_101224207 0.05 ENSMUST00000000543.4
GRP1 (general receptor for phosphoinositides 1)-associated scaffold protein
chr7_-_28598140 0.05 ENSMUST00000040531.8
ENSMUST00000108283.1
sterile alpha motif domain containing 4B
p21 protein (Cdc42/Rac)-activated kinase 4
chr19_+_39007019 0.05 ENSMUST00000025966.4
cytochrome P450, family 2, subfamily c, polypeptide 55
chr1_+_12718496 0.05 ENSMUST00000088585.3
sulfatase 1
chr13_+_31558157 0.05 ENSMUST00000042118.8
forkhead box Q1
chr7_-_19950729 0.05 ENSMUST00000043440.6
immunoglobulin superfamily, member 23
chr11_-_64079444 0.05 ENSMUST00000049091.8
cytochrome c oxidase assembly protein 10
chr5_-_110779937 0.04 ENSMUST00000112426.1
pseudouridine synthase 1
chr9_-_110989611 0.04 ENSMUST00000084922.5
receptor transporter protein 3
chr3_+_129213920 0.04 ENSMUST00000042587.10
paired-like homeodomain transcription factor 2
chr5_+_135187251 0.04 ENSMUST00000002825.5
bromodomain adjacent to zinc finger domain, 1B
chr19_+_4962306 0.04 ENSMUST00000025836.4
mitochondrial ribosomal protein L11
chr7_+_101394361 0.04 ENSMUST00000154239.1
ENSMUST00000098243.2
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 1
chr11_-_100207507 0.04 ENSMUST00000007272.7
keratin 14
chr12_-_83487708 0.03 ENSMUST00000177959.1
ENSMUST00000178756.1
D4, zinc and double PHD fingers, family 3
chr14_+_122534305 0.03 ENSMUST00000154206.1
ENSMUST00000038374.6
ENSMUST00000135578.1
propionyl-Coenzyme A carboxylase, alpha polypeptide
chr10_-_67548944 0.03 ENSMUST00000075686.4
2-aminoethanethiol (cysteamine) dioxygenase
chrX_-_12160355 0.03 ENSMUST00000043441.6
BCL6 interacting corepressor
chr7_+_28881656 0.03 ENSMUST00000066880.4
calpain 12
chr2_-_54085542 0.03 ENSMUST00000100089.2
reprimo, TP53 dependent G2 arrest mediator candidate
chr10_-_119240006 0.02 ENSMUST00000020315.6
cullin associated and neddylation disassociated 1
chr9_+_65101453 0.02 ENSMUST00000077696.6
ENSMUST00000035499.4
ENSMUST00000166273.1
immunoglobulin superfamily, DCC subclass, member 4
chr2_-_30830333 0.02 ENSMUST00000041726.3
ankyrin repeat and SOCS box-containing 6
chr5_-_110780569 0.02 ENSMUST00000149208.1
ENSMUST00000031483.8
ENSMUST00000086643.5
ENSMUST00000170468.1
ENSMUST00000031481.6
pseudouridine synthase 1
chr3_+_32529452 0.02 ENSMUST00000091257.4
mitofusin 1
chr5_-_24451707 0.02 ENSMUST00000101490.1
predicted gene 10472
chrX_+_10485121 0.02 ENSMUST00000076354.6
ENSMUST00000115526.1
tetraspanin 7
chr7_-_4771262 0.02 ENSMUST00000108580.2
family with sequence similarity 71, member E2
chr13_-_93192270 0.02 ENSMUST00000048702.5
PAP associated domain containing 4
chr7_-_4771279 0.02 ENSMUST00000174409.1
family with sequence similarity 71, member E2
chr7_+_43825404 0.02 ENSMUST00000107967.1
kallikrein related-peptidase 6
chr10_+_58813359 0.02 ENSMUST00000135526.2
ENSMUST00000153031.1
SH3 domain containing ring finger 3
chr7_+_45897429 0.02 ENSMUST00000140243.1
transmembrane protein 143
chr14_+_54360826 0.01 ENSMUST00000000985.5
oxidase assembly 1-like
chr19_-_5688149 0.01 ENSMUST00000068169.5
pecanex-like 3 (Drosophila)
chr6_+_22288221 0.01 ENSMUST00000128245.1
ENSMUST00000031681.3
ENSMUST00000148639.1
wingless-related MMTV integration site 16
chr11_-_107337556 0.01 ENSMUST00000040380.6
phosphatidylinositol transfer protein, cytoplasmic 1
chr17_-_34028044 0.01 ENSMUST00000045467.7
ENSMUST00000114303.3
H2-K region expressed gene 6
chr9_-_107606656 0.01 ENSMUST00000073448.5
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
chr2_-_164804876 0.01 ENSMUST00000103094.4
ENSMUST00000017451.6
acyl-CoA thioesterase 8
chr6_+_83054653 0.01 ENSMUST00000092618.6
ancient ubiquitous protein 1
chr4_-_83021102 0.01 ENSMUST00000071708.5
Fras1 related extracellular matrix protein 1
chr15_+_81811414 0.01 ENSMUST00000023024.7
thyrotroph embryonic factor
chr3_+_86224665 0.01 ENSMUST00000107635.1
LPS-responsive beige-like anchor
chr12_+_37242030 0.00 ENSMUST00000160390.1
alkylglycerol monooxygenase
chr2_+_173153048 0.00 ENSMUST00000029017.5
phosphoenolpyruvate carboxykinase 1, cytosolic
chr19_-_3912711 0.00 ENSMUST00000075092.6
NADH dehydrogenase (ubiquinone) Fe-S protein 8
chr1_-_58586191 0.00 ENSMUST00000038372.7
ENSMUST00000097724.3
ENSMUST00000161000.1
ENSMUST00000161600.1
family with sequence similarity 126, member B
chr2_+_130406478 0.00 ENSMUST00000055421.4
transmembrane 239
chr10_-_4432312 0.00 ENSMUST00000126102.1
ENSMUST00000131853.1
ENSMUST00000042251.4
required for meiotic nuclear division 1 homolog (S. cerevisiae)
chr2_+_29869484 0.00 ENSMUST00000047521.6
ENSMUST00000134152.1
cerebral endothelial cell adhesion molecule
chr7_+_45896941 0.00 ENSMUST00000069772.7
ENSMUST00000107716.1
transmembrane protein 143
chr15_-_89429093 0.00 ENSMUST00000170460.1
choline kinase beta
chr1_-_156939387 0.00 ENSMUST00000171292.1
Ral GEF with PH domain and SH3 binding motif 2

Network of associatons between targets according to the STRING database.

First level regulatory network of Nr2c1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.1 0.3 GO:0010636 positive regulation of mitochondrial fusion(GO:0010636)
0.1 0.2 GO:0010710 regulation of collagen catabolic process(GO:0010710) negative regulation of extracellular matrix disassembly(GO:0010716)
0.0 0.1 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.0 0.2 GO:0036151 phosphatidylcholine acyl-chain remodeling(GO:0036151)
0.0 0.6 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.0 0.2 GO:1990928 response to amino acid starvation(GO:1990928)
0.0 0.1 GO:0046049 UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.0 0.3 GO:0014874 response to stimulus involved in regulation of muscle adaptation(GO:0014874)
0.0 0.1 GO:0034769 basement membrane disassembly(GO:0034769)
0.0 0.2 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.0 0.1 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.0 0.4 GO:0006744 ubiquinone biosynthetic process(GO:0006744)
0.0 0.1 GO:0015879 carnitine transport(GO:0015879)
0.0 0.4 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.0 0.3 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.2 GO:0019372 lipoxygenase pathway(GO:0019372)
0.0 0.1 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.0 0.1 GO:0090527 actin filament reorganization(GO:0090527)
0.0 0.1 GO:0043314 negative regulation of neutrophil degranulation(GO:0043314) negative regulation of blood vessel remodeling(GO:0060313)
0.0 0.0 GO:0060578 subthalamic nucleus development(GO:0021763) superior vena cava morphogenesis(GO:0060578)
0.0 0.1 GO:0060903 positive regulation of meiosis I(GO:0060903)
0.0 0.1 GO:0070601 centromeric sister chromatid cohesion(GO:0070601)
0.0 0.0 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.0 0.1 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.0 0.1 GO:1901525 negative regulation of macromitophagy(GO:1901525) regulation of mitophagy in response to mitochondrial depolarization(GO:1904923)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.0 0.6 GO:0045179 apical cortex(GO:0045179)
0.0 0.2 GO:0005683 U7 snRNP(GO:0005683) pICln-Sm protein complex(GO:0034715)
0.0 0.1 GO:0042583 chromaffin granule(GO:0042583)
0.0 0.2 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 0.3 GO:0098799 outer mitochondrial membrane protein complex(GO:0098799)
0.0 0.2 GO:0071438 invadopodium membrane(GO:0071438)
0.0 0.4 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.3 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.1 GO:0031415 NatA complex(GO:0031415)
0.0 0.1 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0000010 trans-hexaprenyltranstransferase activity(GO:0000010) trans-octaprenyltranstransferase activity(GO:0050347)
0.1 0.6 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.1 0.2 GO:0030156 benzodiazepine receptor binding(GO:0030156)
0.0 0.1 GO:0008311 double-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008311)
0.0 0.1 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.0 0.1 GO:0005124 scavenger receptor binding(GO:0005124)
0.0 0.1 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.0 0.1 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.1 GO:0004738 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.0 0.1 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0 0.2 GO:0001055 RNA polymerase II activity(GO:0001055)
0.0 0.2 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.0 GO:0004658 propionyl-CoA carboxylase activity(GO:0004658)
0.0 0.1 GO:0016416 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs