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2D miR_HR1_12

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Results for Tlx2

Z-value: 0.98

Motif logo

Transcription factors associated with Tlx2

Gene Symbol Gene ID Gene Info
ENSMUSG00000068327.3 T cell leukemia, homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Tlx2mm10_v2_chr6_-_83070225_83070377-0.411.8e-01Click!

Activity profile of Tlx2 motif

Sorted Z-values of Tlx2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr3_+_90669063 1.25 ENSMUST00000069927.8
S100 calcium binding protein A8 (calgranulin A)
chr3_-_90695706 1.07 ENSMUST00000069960.5
ENSMUST00000117167.1
S100 calcium binding protein A9 (calgranulin B)
chr7_+_30493622 1.05 ENSMUST00000058280.6
ENSMUST00000133318.1
ENSMUST00000142575.1
ENSMUST00000131040.1
proline dehydrogenase (oxidase) 2
chr17_+_17887840 0.82 ENSMUST00000054871.5
ENSMUST00000064068.4
formyl peptide receptor 3
formyl peptide receptor 2
chr12_+_100779074 0.80 ENSMUST00000110073.1
ENSMUST00000110070.1
RIKEN cDNA 9030617O03 gene
chr7_-_46715676 0.78 ENSMUST00000006956.7
serum amyloid A 3
chr5_-_137858034 0.77 ENSMUST00000110978.2
paired immunoglobin-like type 2 receptor beta 1
chr12_+_100779088 0.72 ENSMUST00000110069.1
RIKEN cDNA 9030617O03 gene
chr7_-_30924169 0.71 ENSMUST00000074671.6
hepcidin antimicrobial peptide 2
chr8_+_13037802 0.66 ENSMUST00000152034.1
ENSMUST00000128418.1
coagulation factor X
chr3_-_113574758 0.65 ENSMUST00000106540.1
amylase 1, salivary
chr4_-_141846277 0.64 ENSMUST00000105781.1
chymotrypsin C (caldecrin)
chr3_-_113574242 0.63 ENSMUST00000142505.2
amylase 1, salivary
chr4_-_141846359 0.60 ENSMUST00000037059.10
chymotrypsin C (caldecrin)
chr15_-_100687908 0.59 ENSMUST00000023775.7
chymotrypsin-like elastase family, member 1
chr4_-_4138432 0.58 ENSMUST00000070375.7
preproenkephalin
chr6_+_117168535 0.58 ENSMUST00000112866.1
ENSMUST00000112871.1
ENSMUST00000073043.4
chemokine (C-X-C motif) ligand 12
chr8_-_105933832 0.58 ENSMUST00000034368.6
chymotrypsin-like
chr9_+_124121534 0.57 ENSMUST00000111442.1
ENSMUST00000171499.2
chemokine (C-C motif) receptor 5
chr11_+_4236411 0.57 ENSMUST00000075221.2
oncostatin M
chr14_+_44988192 0.56 ENSMUST00000046891.5
prostaglandin E receptor 2 (subtype EP2)
chr7_-_127137807 0.54 ENSMUST00000049931.5
sialophorin
chr3_-_59130610 0.53 ENSMUST00000065220.6
ENSMUST00000091112.4
purinergic receptor P2Y, G-protein coupled, 14
chr13_-_49309217 0.51 ENSMUST00000110087.2
FYVE, RhoGEF and PH domain containing 3
chr6_+_38918969 0.51 ENSMUST00000003017.6
thromboxane A synthase 1, platelet
chr15_+_35296090 0.49 ENSMUST00000022952.4
odd-skipped related 2
chr1_-_150466165 0.47 ENSMUST00000162367.1
ENSMUST00000161611.1
ENSMUST00000161320.1
ENSMUST00000159035.1
proteoglycan 4 (megakaryocyte stimulating factor, articular superficial zone protein)
chr2_+_165055625 0.47 ENSMUST00000017799.5
ENSMUST00000073707.2
CD40 antigen
chr7_+_28437447 0.45 ENSMUST00000108292.2
ENSMUST00000108289.1
glia maturation factor, gamma
chr16_-_3718105 0.44 ENSMUST00000023180.7
ENSMUST00000100222.2
Mediterranean fever
chr2_-_121235689 0.44 ENSMUST00000142400.1
transformation related protein 53 binding protein 1
chr7_-_3915501 0.44 ENSMUST00000038176.8
ENSMUST00000090689.4
leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 6
chr2_-_176319494 0.42 ENSMUST00000108961.3
predicted gene 11009
chr10_+_79890853 0.41 ENSMUST00000061653.7
complement factor D (adipsin)
chr11_-_52282564 0.41 ENSMUST00000086844.3
transcription factor 7, T cell specific
chr3_-_96293953 0.41 ENSMUST00000029748.3
Fc receptor, IgG, high affinity I
chr10_+_80016653 0.41 ENSMUST00000099501.3
histocompatibility (minor) HA-1
chr7_-_57386871 0.40 ENSMUST00000068394.6
gamma-aminobutyric acid (GABA) A receptor, subunit gamma 3
chr17_-_31144271 0.40 ENSMUST00000024826.7
trefoil factor 2 (spasmolytic protein 1)
chr6_-_124636085 0.39 ENSMUST00000068797.2
predicted gene 5077
chr8_+_92827273 0.39 ENSMUST00000034187.7
matrix metallopeptidase 2
chr2_+_173659834 0.39 ENSMUST00000109110.3
RAB22A, member RAS oncogene family
chr9_+_124102110 0.39 ENSMUST00000168841.1
ENSMUST00000055918.6
chemokine (C-C motif) receptor 2
chr10_-_128298084 0.39 ENSMUST00000026449.1
interleukin 23, alpha subunit p19
chr4_+_155469114 0.38 ENSMUST00000178188.1
ENSMUST00000178238.1
ENSMUST00000023920.2
transmembrane protein 52
chr11_-_115027012 0.38 ENSMUST00000100240.2
predicted gene 11710
chr8_+_104340594 0.38 ENSMUST00000034343.4
CKLF-like MARVEL transmembrane domain containing 3
chr11_+_95837216 0.38 ENSMUST00000107712.1
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2
chr8_-_111691002 0.37 ENSMUST00000034435.5
chymotrypsinogen B1
chr18_+_60376029 0.37 ENSMUST00000066912.5
ENSMUST00000032473.6
interferon inducible GTPase 1
chrX_-_155623325 0.36 ENSMUST00000038665.5
patched domain containing 1
chr9_+_108080436 0.36 ENSMUST00000035211.7
ENSMUST00000162886.1
macrophage stimulating 1 (hepatocyte growth factor-like)
chr2_+_173659760 0.36 ENSMUST00000029024.3
RAB22A, member RAS oncogene family
chr17_+_35194502 0.36 ENSMUST00000173600.1
lymphotoxin B
chr6_+_78405148 0.35 ENSMUST00000023906.2
regenerating islet-derived 2
chr4_+_148643317 0.35 ENSMUST00000105698.2
predicted gene 572
chr4_-_99654983 0.35 ENSMUST00000136525.1
predicted gene 12688
chr8_-_122551316 0.34 ENSMUST00000067252.7
piezo-type mechanosensitive ion channel component 1
chr17_+_35194405 0.34 ENSMUST00000025262.5
lymphotoxin B
chr4_-_46138667 0.34 ENSMUST00000147837.1
thiosulfate sulfurtransferase (rhodanese)-like domain containing 2
chr7_-_141016892 0.34 ENSMUST00000081924.3
interferon induced transmembrane protein 6
chr2_-_30903255 0.33 ENSMUST00000102852.3
prostaglandin E synthase
chr14_+_32785963 0.33 ENSMUST00000039191.6
RIKEN cDNA 1810011H11 gene
chr5_-_137871739 0.33 ENSMUST00000164886.1
paired immunoglobin-like type 2 receptor beta 2
chr2_-_126499839 0.33 ENSMUST00000040128.5
ATPase, class I, type 8B, member 4
chr11_-_115133981 0.32 ENSMUST00000106561.1
ENSMUST00000051264.7
ENSMUST00000106562.2
CD300 antigen like family member F
chr4_+_135728116 0.32 ENSMUST00000102546.3
interleukin 22 receptor, alpha 1
chr17_+_35439155 0.31 ENSMUST00000071951.6
ENSMUST00000078205.7
ENSMUST00000116598.3
ENSMUST00000076256.7
histocompatibility 2, Q region locus 7
chr9_-_48605147 0.31 ENSMUST00000034808.5
ENSMUST00000119426.1
nicotinamide N-methyltransferase
chr11_+_106751255 0.30 ENSMUST00000183111.1
ENSMUST00000106794.2
mast cell immunoglobulin like receptor 1
chrX_-_51205990 0.30 ENSMUST00000114876.2
muscleblind-like 3 (Drosophila)
chr9_-_103219823 0.30 ENSMUST00000168142.1
transferrin
chr8_+_65618009 0.30 ENSMUST00000110258.1
ENSMUST00000110256.1
ENSMUST00000110255.1
membrane-associated ring finger (C3HC4) 1
chr11_+_106751226 0.30 ENSMUST00000147326.2
ENSMUST00000182896.1
ENSMUST00000182908.1
ENSMUST00000086353.4
mast cell immunoglobulin like receptor 1
chr9_-_58313189 0.29 ENSMUST00000061799.8
lysyl oxidase-like 1
chr2_+_122636962 0.29 ENSMUST00000142767.1
expressed sequence AA467197
chr2_-_150668198 0.29 ENSMUST00000028944.3
acyl-CoA synthetase short-chain family member 1
chr12_+_24651346 0.29 ENSMUST00000020982.5
Kruppel-like factor 11
chr5_-_123141067 0.28 ENSMUST00000162697.1
ENSMUST00000160321.1
ENSMUST00000159637.1
expressed sequence AI480526
chr1_-_36273425 0.28 ENSMUST00000056946.6
neuralized homolog 3 homolog (Drosophila)
chr14_+_66344296 0.28 ENSMUST00000152093.1
ENSMUST00000074523.6
stathmin-like 4
chr4_-_49506538 0.27 ENSMUST00000043056.2
bile acid-Coenzyme A: amino acid N-acyltransferase
chr17_+_34263209 0.27 ENSMUST00000040828.5
histocompatibility 2, class II antigen A, beta 1
chr10_+_79879614 0.27 ENSMUST00000006679.8
proteinase 3
chr1_-_162898665 0.27 ENSMUST00000111510.1
ENSMUST00000045902.6
flavin containing monooxygenase 2
chr7_-_30598863 0.27 ENSMUST00000108150.1
zinc finger and BTB domain containing 32
chr4_-_117929466 0.26 ENSMUST00000097913.2
artemin
chr5_-_105051047 0.26 ENSMUST00000112718.4
guanylate-binding protein 8
chr4_-_149698698 0.26 ENSMUST00000038859.7
ENSMUST00000105690.2
phosphatidylinositol 3-kinase catalytic delta polypeptide
chr2_+_136891501 0.26 ENSMUST00000141463.1
SLX4 interacting protein
chr1_-_136960427 0.26 ENSMUST00000027649.7
nuclear receptor subfamily 5, group A, member 2
chr9_+_124101944 0.26 ENSMUST00000171719.1
chemokine (C-C motif) receptor 2
chr1_-_193370225 0.26 ENSMUST00000169907.1
calcium/calmodulin-dependent protein kinase I gamma
chr5_-_62765618 0.25 ENSMUST00000159470.1
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr11_+_116593687 0.25 ENSMUST00000153476.1
arylalkylamine N-acetyltransferase
chr13_-_19824234 0.24 ENSMUST00000065335.2
G protein-coupled receptor 141
chrX_+_73503074 0.24 ENSMUST00000114479.1
ENSMUST00000088429.1
ENSMUST00000033744.5
ATPase, Ca++ transporting, plasma membrane 3
chr11_-_109472611 0.24 ENSMUST00000168740.1
solute carrier family 16 (monocarboxylic acid transporters), member 6
chr13_+_74121435 0.24 ENSMUST00000036208.6
solute carrier family 9 (sodium/hydrogen exchanger), member 3
chr5_+_34543365 0.24 ENSMUST00000101316.3
SH3-domain binding protein 2
chr4_-_128962420 0.24 ENSMUST00000119354.1
ENSMUST00000106068.1
ENSMUST00000030581.3
arginine decarboxylase
chr17_-_73950172 0.23 ENSMUST00000024866.4
xanthine dehydrogenase
chr3_-_88378699 0.23 ENSMUST00000098956.2
bone gamma-carboxyglutamate protein 2
chr9_-_31464238 0.23 ENSMUST00000048050.7
transmembrane protein 45b
chr13_-_49320219 0.23 ENSMUST00000110086.1
FYVE, RhoGEF and PH domain containing 3
chr7_-_126583177 0.23 ENSMUST00000098036.2
ENSMUST00000032962.4
ceroid lipofuscinosis, neuronal 3, juvenile (Batten, Spielmeyer-Vogt disease)
chr18_-_56925509 0.22 ENSMUST00000102912.1
membrane-associated ring finger (C3HC4) 3
chr7_+_29170345 0.22 ENSMUST00000033886.7
gametogenetin
chr17_+_68837062 0.22 ENSMUST00000178545.1
transmembrane protein 200C
chr13_+_102693522 0.22 ENSMUST00000022124.3
ENSMUST00000171267.1
ENSMUST00000167144.1
ENSMUST00000170878.1
CD180 antigen
chr16_-_36666067 0.21 ENSMUST00000089620.4
CD86 antigen
chr3_-_32365643 0.21 ENSMUST00000029199.5
zinc finger matrin type 3
chr12_+_98268626 0.21 ENSMUST00000075072.4
G-protein coupled receptor 65
chr16_-_56886131 0.20 ENSMUST00000023435.5
transmembrane protein 45a
chr9_-_40984460 0.20 ENSMUST00000180872.1
cytotoxic and regulatory T cell molecule
chr9_+_108648720 0.20 ENSMUST00000098384.2
predicted gene 10621
chr10_-_115362191 0.20 ENSMUST00000092170.5
transmembrane protein 19
chr3_-_32365608 0.19 ENSMUST00000168566.1
zinc finger matrin type 3
chr15_+_21111452 0.19 ENSMUST00000075132.6
cadherin 12
chr19_+_56287911 0.19 ENSMUST00000095948.4
hyaluronic acid binding protein 2
chr11_-_69695521 0.18 ENSMUST00000181261.1
tumor necrosis factor (ligand) superfamily, member 12
chr3_+_36475932 0.18 ENSMUST00000029268.6
RIKEN cDNA 1810062G17 gene
chr9_+_123034731 0.18 ENSMUST00000026893.4
transglutaminase 4 (prostate)
chr12_+_99964499 0.18 ENSMUST00000177549.1
ENSMUST00000160413.1
ENSMUST00000162221.1
ENSMUST00000049788.8
potassium channel, subfamily K, member 13
chr6_+_122513583 0.18 ENSMUST00000032210.7
ENSMUST00000148517.1
microfibrillar associated protein 5
chr9_-_58201705 0.18 ENSMUST00000163200.1
ENSMUST00000165276.1
immunoglobulin superfamily containing leucine-rich repeat 2
chr4_-_46138398 0.18 ENSMUST00000144495.1
ENSMUST00000107770.1
ENSMUST00000156021.1
ENSMUST00000107772.1
thiosulfate sulfurtransferase (rhodanese)-like domain containing 2
chr5_+_108864833 0.18 ENSMUST00000177581.1
predicted gene 10417
chr7_-_44306903 0.18 ENSMUST00000004587.9
C-type lectin domain family 11, member a
chr15_-_103340085 0.18 ENSMUST00000168828.1
zinc finger protein 385A
chr11_+_85832551 0.18 ENSMUST00000000095.6
T-box 2
chr19_-_4121536 0.17 ENSMUST00000025767.7
aryl-hydrocarbon receptor-interacting protein
chr2_+_38511643 0.17 ENSMUST00000054234.3
ENSMUST00000112902.1
ENSMUST00000112895.1
NIMA (never in mitosis gene a)-related expressed kinase 6
chr8_-_25101734 0.17 ENSMUST00000098866.4
pleckstrin homology domain-containing, family A (phosphoinositide binding specific) member 2
chr11_+_3332426 0.17 ENSMUST00000136474.1
phosphoinositide-3-kinase interacting protein 1
chr9_-_71771535 0.17 ENSMUST00000122065.1
ENSMUST00000121322.1
ENSMUST00000072899.2
cingulin-like 1
chr5_-_145879857 0.17 ENSMUST00000035918.7
cytochrome P450, family 3, subfamily a, polypeptide 11
chr12_+_69241832 0.17 ENSMUST00000063445.6
kelch domain containing 1
chr1_-_193370260 0.17 ENSMUST00000016323.4
calcium/calmodulin-dependent protein kinase I gamma
chr10_+_41476314 0.17 ENSMUST00000119962.1
ENSMUST00000019967.9
ENSMUST00000099934.4
microtubule associated monooxygenase, calponin and LIM domain containing 1
chr5_-_24601961 0.16 ENSMUST00000030791.7
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
chr9_-_40964118 0.16 ENSMUST00000034521.7
RIKEN cDNA 4931429I11 gene
chr11_+_115900125 0.16 ENSMUST00000142089.1
ENSMUST00000131566.1
small integral membrane protein 5
chr9_+_107399858 0.16 ENSMUST00000085092.5
ENSMUST00000164988.2
calcium channel, voltage-dependent, alpha 2/delta subunit 2
chr18_-_3337467 0.16 ENSMUST00000154135.1
cAMP responsive element modulator
chr1_-_162859684 0.16 ENSMUST00000131058.1
flavin containing monooxygenase 1
chr10_+_79988584 0.16 ENSMUST00000004784.4
ENSMUST00000105374.1
calponin 2
chr15_-_99457712 0.16 ENSMUST00000161948.1
NCK-associated protein 5-like
chr8_+_121116163 0.16 ENSMUST00000054691.6
forkhead box C2
chr11_-_69921057 0.16 ENSMUST00000108609.1
ENSMUST00000108608.1
ENSMUST00000164359.1
eukaryotic translation initiation factor 5A
chr7_-_12422751 0.16 ENSMUST00000080348.5
zinc fingr protein 551
chr10_+_91082940 0.16 ENSMUST00000020150.3
IKBKB interacting protein
chr10_-_127621107 0.16 ENSMUST00000049149.8
low density lipoprotein receptor-related protein 1
chr1_-_139858684 0.16 ENSMUST00000094489.3
complement factor H-related 2
chr1_-_91459254 0.15 ENSMUST00000069620.8
period circadian clock 2
chr6_-_147243794 0.15 ENSMUST00000153786.1
predicted gene 15767
chr17_-_23835743 0.15 ENSMUST00000059906.6
protease, serine, 33
chr9_-_121839460 0.15 ENSMUST00000135986.2
coiled-coil domain containing 13
chr11_-_4160286 0.15 ENSMUST00000093381.4
ENSMUST00000101626.2
coiled-coil domain containing 157
chr6_+_14901440 0.15 ENSMUST00000128567.1
forkhead box P2
chr7_-_44532064 0.15 ENSMUST00000098483.2
ENSMUST00000035323.4
Spi-B transcription factor (Spi-1/PU.1 related)
chr11_-_69920892 0.15 ENSMUST00000152589.1
ENSMUST00000108612.1
ENSMUST00000108611.1
eukaryotic translation initiation factor 5A
chr18_+_20247340 0.15 ENSMUST00000054128.6
desmoglein 1 gamma
chr6_+_125215551 0.15 ENSMUST00000032487.7
ENSMUST00000100942.2
ENSMUST00000063588.8
vesicle-associated membrane protein 1
chr16_-_45693658 0.15 ENSMUST00000114562.2
ENSMUST00000036617.7
transmembrane serine protease 7
chr7_+_131410601 0.15 ENSMUST00000015829.7
ENSMUST00000117518.1
acyl-Coenzyme A dehydrogenase, short/branched chain
chr13_-_68999518 0.15 ENSMUST00000022013.7
adenylate cyclase 2
chr17_-_24632608 0.15 ENSMUST00000097373.1
tuberous sclerosis 2
chr12_-_31950170 0.15 ENSMUST00000176520.1
high mobility group box transcription factor 1
chr11_+_61022560 0.15 ENSMUST00000089184.4
potassium inwardly-rectifying channel, subfamily J, member 12
chr2_+_151542483 0.15 ENSMUST00000044011.5
FK506 binding protein 1a
chr11_+_44400060 0.15 ENSMUST00000102796.3
ENSMUST00000170513.1
interleukin 12b
chr5_+_22550391 0.15 ENSMUST00000181374.1
ENSMUST00000181764.1
ENSMUST00000181209.1
RIKEN cDNA 6030443J06 gene
chr4_-_149698552 0.14 ENSMUST00000134534.1
ENSMUST00000146612.1
ENSMUST00000105688.3
phosphatidylinositol 3-kinase catalytic delta polypeptide
chr12_-_31950210 0.14 ENSMUST00000176084.1
ENSMUST00000176103.1
ENSMUST00000167458.2
high mobility group box transcription factor 1
chr2_-_180954620 0.14 ENSMUST00000139929.1
Na+/K+ transporting ATPase interacting 4
chr5_+_114146525 0.14 ENSMUST00000102582.1
acetyl-Coenzyme A carboxylase beta
chr2_+_156008088 0.14 ENSMUST00000088650.4
ERGIC and golgi 3
chr19_+_56287943 0.14 ENSMUST00000166049.1
hyaluronic acid binding protein 2
chr19_-_11266122 0.14 ENSMUST00000169159.1
membrane-spanning 4-domains, subfamily A, member 1
chr2_-_181039160 0.14 ENSMUST00000108851.1
cholinergic receptor, nicotinic, alpha polypeptide 4
chr18_-_3281036 0.14 ENSMUST00000049942.6
ENSMUST00000139537.1
ENSMUST00000124747.1
cAMP responsive element modulator
chr14_+_34085978 0.14 ENSMUST00000022519.8
annexin A8
chr2_+_156008045 0.14 ENSMUST00000006035.6
ERGIC and golgi 3
chr6_+_124808885 0.14 ENSMUST00000143040.1
ENSMUST00000052727.4
ENSMUST00000130160.1
splA/ryanodine receptor domain and SOCS box containing 2
chr7_+_43018798 0.14 ENSMUST00000173815.1
ENSMUST00000166914.1
predicted gene 9268
chr8_+_67494843 0.14 ENSMUST00000093470.5
ENSMUST00000163856.1
N-acetyltransferase 2 (arylamine N-acetyltransferase)
chr10_+_91083036 0.14 ENSMUST00000020149.5
IKBKB interacting protein
chr2_-_117342949 0.14 ENSMUST00000102534.4
RAS guanyl releasing protein 1
chr2_-_117342831 0.13 ENSMUST00000178884.1
RAS guanyl releasing protein 1
chr10_+_81575499 0.13 ENSMUST00000143285.1
ENSMUST00000146358.1
transducin-like enhancer of split 2, homolog of Drosophila E(spl)
chr14_+_74640840 0.13 ENSMUST00000036653.3
5-hydroxytryptamine (serotonin) receptor 2A
chr7_-_109438786 0.13 ENSMUST00000121748.1
serine/threonine kinase 33
chr5_-_62766153 0.13 ENSMUST00000076623.4
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr4_+_134396320 0.13 ENSMUST00000105869.2
platelet-activating factor acetylhydrolase 2
chr2_-_127729872 0.13 ENSMUST00000028856.2
mal, T cell differentiation protein-like
chr1_-_10719898 0.12 ENSMUST00000035577.6
carboxypeptidase A6
chr17_-_35980197 0.12 ENSMUST00000055454.7
proline-rich polypeptide 3
chr12_-_31950535 0.12 ENSMUST00000172314.2
high mobility group box transcription factor 1
chr11_-_69695753 0.12 ENSMUST00000180946.1
tumor necrosis factor (ligand) superfamily, member 12

Network of associatons between targets according to the STRING database.

First level regulatory network of Tlx2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.3 GO:0070488 neutrophil aggregation(GO:0070488)
0.3 1.0 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.2 0.6 GO:2000451 immune complex clearance by monocytes and macrophages(GO:0002436) astrocyte chemotaxis(GO:0035700) regulation of immune complex clearance by monocytes and macrophages(GO:0090264) positive regulation of immune complex clearance by monocytes and macrophages(GO:0090265) negative regulation of eosinophil activation(GO:1902567) positive regulation of CD8-positive, alpha-beta T cell extravasation(GO:2000451) regulation of astrocyte chemotaxis(GO:2000458)
0.2 0.8 GO:0097494 regulation of vesicle size(GO:0097494)
0.2 0.5 GO:0002884 type IV hypersensitivity(GO:0001806) negative regulation of hypersensitivity(GO:0002884)
0.2 0.7 GO:0034760 negative regulation of iron ion transport(GO:0034757) negative regulation of iron ion transmembrane transport(GO:0034760)
0.2 0.2 GO:0007521 muscle cell fate determination(GO:0007521)
0.1 0.4 GO:0071846 actin filament debranching(GO:0071846)
0.1 0.6 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
0.1 0.7 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.1 0.8 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.1 0.4 GO:0001788 antibody-dependent cellular cytotoxicity(GO:0001788)
0.1 0.5 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.1 0.5 GO:0010536 positive regulation of activation of Janus kinase activity(GO:0010536)
0.1 0.9 GO:0061113 pancreas morphogenesis(GO:0061113)
0.1 0.5 GO:0036022 limb joint morphogenesis(GO:0036022) embryonic skeletal limb joint morphogenesis(GO:0036023)
0.1 0.6 GO:1903367 positive regulation of fear response(GO:1903367) positive regulation of behavioral fear response(GO:2000987)
0.1 0.6 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.1 0.6 GO:0052151 positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation of apoptotic process by virus(GO:0060139)
0.1 0.4 GO:0071608 macrophage inflammatory protein-1 alpha production(GO:0071608)
0.1 0.4 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.1 0.3 GO:0002344 peripheral B cell selection(GO:0002343) B cell affinity maturation(GO:0002344)
0.1 0.3 GO:0097021 lymphocyte migration into lymphoid organs(GO:0097021)
0.1 0.3 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.1 0.3 GO:2000426 regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124) TRIF-dependent toll-like receptor signaling pathway(GO:0035666) interleukin-4-mediated signaling pathway(GO:0035771) response to interleukin-13(GO:0035962) cellular response to interleukin-13(GO:0035963) negative regulation of apoptotic cell clearance(GO:2000426)
0.1 0.2 GO:1903048 regulation of acetylcholine-gated cation channel activity(GO:1903048)
0.1 0.2 GO:0002644 negative regulation of tolerance induction(GO:0002644)
0.1 0.3 GO:0097029 mature conventional dendritic cell differentiation(GO:0097029)
0.1 0.2 GO:0002355 detection of tumor cell(GO:0002355)
0.1 0.5 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.1 0.2 GO:1902162 regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162)
0.1 0.4 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.1 0.2 GO:0009115 xanthine catabolic process(GO:0009115)
0.1 0.5 GO:0043031 negative regulation of macrophage activation(GO:0043031)
0.1 0.1 GO:1902523 positive regulation of protein K63-linked ubiquitination(GO:1902523)
0.1 0.3 GO:0072592 oxygen metabolic process(GO:0072592)
0.1 0.2 GO:0003275 apoptotic process involved in outflow tract morphogenesis(GO:0003275) regulation of apoptotic process involved in outflow tract morphogenesis(GO:1902256)
0.1 0.5 GO:0045409 negative regulation of interleukin-6 biosynthetic process(GO:0045409)
0.1 0.4 GO:0033153 somatic diversification of T cell receptor genes(GO:0002568) somatic recombination of T cell receptor gene segments(GO:0002681) T cell receptor V(D)J recombination(GO:0033153)
0.1 0.3 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.1 0.2 GO:0031554 regulation of DNA-templated transcription, termination(GO:0031554)
0.0 0.1 GO:0002408 myeloid dendritic cell chemotaxis(GO:0002408)
0.0 0.2 GO:1990034 calcium ion export from cell(GO:1990034)
0.0 0.3 GO:0006083 acetate metabolic process(GO:0006083) short-chain fatty acid biosynthetic process(GO:0051790)
0.0 0.4 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.0 0.1 GO:0046949 fatty-acyl-CoA biosynthetic process(GO:0046949) malonyl-CoA metabolic process(GO:2001293)
0.0 0.4 GO:1903874 ferrous iron transmembrane transport(GO:1903874)
0.0 0.2 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
0.0 0.1 GO:0010513 phospholipase C-activating serotonin receptor signaling pathway(GO:0007208) positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.0 0.6 GO:0033004 negative regulation of mast cell activation(GO:0033004)
0.0 0.1 GO:1905167 positive regulation of lysosomal protein catabolic process(GO:1905167)
0.0 0.1 GO:0042450 arginine biosynthetic process via ornithine(GO:0042450)
0.0 0.5 GO:0032570 response to progesterone(GO:0032570)
0.0 0.4 GO:0060763 mammary duct terminal end bud growth(GO:0060763)
0.0 0.1 GO:2000872 positive regulation of progesterone secretion(GO:2000872)
0.0 0.8 GO:0035634 response to stilbenoid(GO:0035634)
0.0 0.1 GO:0048550 protein transport into plasma membrane raft(GO:0044861) negative regulation of pinocytosis(GO:0048550)
0.0 0.1 GO:0070375 ERK5 cascade(GO:0070375)
0.0 0.8 GO:0045671 negative regulation of osteoclast differentiation(GO:0045671)
0.0 0.5 GO:0090037 positive regulation of protein kinase C signaling(GO:0090037)
0.0 0.1 GO:0061033 secretion by lung epithelial cell involved in lung growth(GO:0061033)
0.0 0.1 GO:2000562 negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562)
0.0 0.0 GO:0010888 negative regulation of lipid storage(GO:0010888) negative regulation of sequestering of triglyceride(GO:0010891)
0.0 0.4 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.1 GO:0042977 regulation of activation of JAK2 kinase activity(GO:0010534) activation of JAK2 kinase activity(GO:0042977) negative regulation of activation of JAK2 kinase activity(GO:1902569)
0.0 0.1 GO:1902093 thymocyte migration(GO:0072679) positive regulation of sperm motility(GO:1902093)
0.0 0.4 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.0 0.1 GO:2000978 negative regulation of forebrain neuron differentiation(GO:2000978)
0.0 0.1 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.0 0.1 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.0 0.3 GO:0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.0 0.4 GO:0010745 negative regulation of macrophage derived foam cell differentiation(GO:0010745)
0.0 0.1 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.0 0.2 GO:0003219 cardiac right ventricle formation(GO:0003219)
0.0 0.1 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.0 0.1 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.0 0.1 GO:0001992 regulation of systemic arterial blood pressure by vasopressin(GO:0001992)
0.0 0.2 GO:0022417 protein maturation by protein folding(GO:0022417)
0.0 0.2 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.0 0.0 GO:0007172 signal complex assembly(GO:0007172) regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538)
0.0 0.1 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.0 0.2 GO:0060024 rhythmic synaptic transmission(GO:0060024)
0.0 0.2 GO:0007320 insemination(GO:0007320)
0.0 0.1 GO:0014064 positive regulation of serotonin secretion(GO:0014064) negative regulation of luteinizing hormone secretion(GO:0033685)
0.0 0.1 GO:0015851 nucleobase transport(GO:0015851) pyrimidine nucleobase transport(GO:0015855)
0.0 0.1 GO:0061300 cerebellum vasculature development(GO:0061300)
0.0 0.2 GO:0042435 indole-containing compound biosynthetic process(GO:0042435)
0.0 0.1 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.0 0.1 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0 0.3 GO:1902715 positive regulation of interferon-gamma secretion(GO:1902715)
0.0 0.1 GO:0061589 calcium activated phosphatidylserine scrambling(GO:0061589)
0.0 0.1 GO:0010898 positive regulation of triglyceride catabolic process(GO:0010898)
0.0 0.1 GO:0042723 thiamine metabolic process(GO:0006772) thiamine-containing compound metabolic process(GO:0042723) positive regulation of adenosine receptor signaling pathway(GO:0060168)
0.0 0.1 GO:0038044 transforming growth factor-beta secretion(GO:0038044)
0.0 0.2 GO:0030035 microspike assembly(GO:0030035)
0.0 0.1 GO:0036233 glycine import(GO:0036233)
0.0 0.3 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.4 GO:0021794 thalamus development(GO:0021794)
0.0 0.1 GO:0035437 maintenance of protein localization in endoplasmic reticulum(GO:0035437)
0.0 0.1 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.1 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.0 0.1 GO:0015820 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.0 0.3 GO:0006699 bile acid biosynthetic process(GO:0006699)
0.0 0.1 GO:0070459 prolactin secretion(GO:0070459)
0.0 0.4 GO:0001967 suckling behavior(GO:0001967)
0.0 0.4 GO:0097435 fibril organization(GO:0097435)
0.0 0.0 GO:0046619 optic placode formation involved in camera-type eye formation(GO:0046619)
0.0 0.2 GO:0070995 NADPH oxidation(GO:0070995)
0.0 0.1 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.0 0.1 GO:0006680 glucosylceramide catabolic process(GO:0006680) positive regulation of phospholipid catabolic process(GO:0060697)
0.0 0.1 GO:2000189 positive regulation of cholesterol homeostasis(GO:2000189)
0.0 0.1 GO:0002517 T cell tolerance induction(GO:0002517)
0.0 0.2 GO:1904322 response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.0 0.5 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.1 GO:0021776 smoothened signaling pathway involved in ventral spinal cord interneuron specification(GO:0021775) smoothened signaling pathway involved in spinal cord motor neuron cell fate specification(GO:0021776)
0.0 0.3 GO:0001516 prostaglandin biosynthetic process(GO:0001516) prostanoid biosynthetic process(GO:0046457)
0.0 0.0 GO:2000016 negative regulation of determination of dorsal identity(GO:2000016)
0.0 0.2 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.0 0.0 GO:0071651 positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651)
0.0 0.1 GO:0043973 histone H3-K4 acetylation(GO:0043973)
0.0 0.0 GO:0006562 proline catabolic process(GO:0006562)
0.0 0.0 GO:0051977 lysophospholipid transport(GO:0051977) positive regulation of arachidonic acid secretion(GO:0090238)
0.0 0.1 GO:0070474 positive regulation of uterine smooth muscle contraction(GO:0070474)
0.0 0.1 GO:0070253 somatostatin secretion(GO:0070253)
0.0 0.0 GO:0010593 negative regulation of lamellipodium assembly(GO:0010593)
0.0 0.1 GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I(GO:0042590)
0.0 0.2 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.0 0.1 GO:0007296 vitellogenesis(GO:0007296)
0.0 0.2 GO:0050765 negative regulation of phagocytosis(GO:0050765)
0.0 0.0 GO:0002322 B cell proliferation involved in immune response(GO:0002322)
0.0 0.3 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.0 0.0 GO:1902938 trans-synaptic signaling by lipid(GO:0099541) trans-synaptic signaling by endocannabinoid(GO:0099542) trans-synaptic signaling by lipid, modulating synaptic transmission(GO:0099552) trans-synaptic signaling by endocannabinoid, modulating synaptic transmission(GO:0099553) regulation of intracellular calcium activated chloride channel activity(GO:1902938)
0.0 0.4 GO:0042832 defense response to protozoan(GO:0042832)
0.0 0.1 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0032280 symmetric synapse(GO:0032280)
0.1 0.6 GO:0042629 mast cell granule(GO:0042629)
0.0 0.1 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.0 0.5 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.1 GO:0034685 integrin alphav-beta6 complex(GO:0034685)
0.0 0.2 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 0.1 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.4 GO:0020005 symbiont-containing vacuole membrane(GO:0020005)
0.0 0.1 GO:0070820 tertiary granule(GO:0070820)
0.0 0.5 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 0.3 GO:0097433 dense body(GO:0097433)
0.0 0.3 GO:0005642 annulate lamellae(GO:0005642)
0.0 0.3 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 0.1 GO:0097233 lamellar body membrane(GO:0097232) alveolar lamellar body membrane(GO:0097233)
0.0 0.1 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.0 0.3 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.6 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.2 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.1 GO:0000836 ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836)
0.0 0.3 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.2 GO:0070852 cell body fiber(GO:0070852)
0.0 0.3 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.1 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.0 0.2 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.1 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.0 0.4 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.3 GO:0030057 desmosome(GO:0030057)
0.0 0.1 GO:0002177 manchette(GO:0002177)
0.0 0.1 GO:0097524 sperm plasma membrane(GO:0097524)
0.0 0.7 GO:0045335 phagocytic vesicle(GO:0045335)
0.0 0.4 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.1 GO:1903440 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.1 GO:0050786 RAGE receptor binding(GO:0050786)
0.2 0.6 GO:0035717 chemokine (C-C motif) ligand 7 binding(GO:0035717)
0.2 1.3 GO:0004556 alpha-amylase activity(GO:0004556)
0.1 0.8 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.1 0.4 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.1 0.3 GO:0042015 interleukin-20 binding(GO:0042015)
0.1 0.7 GO:0019957 C-C chemokine binding(GO:0019957)
0.1 0.7 GO:0001515 opioid peptide activity(GO:0001515)
0.1 0.3 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.1 0.6 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.1 0.3 GO:0030116 glial cell-derived neurotrophic factor receptor binding(GO:0030116)
0.1 0.3 GO:0050220 prostaglandin-D synthase activity(GO:0004667) prostaglandin-E synthase activity(GO:0050220)
0.1 0.4 GO:0019770 IgG receptor activity(GO:0019770)
0.1 1.0 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.1 0.4 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.1 0.3 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.1 0.4 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.1 0.2 GO:0008147 structural constituent of bone(GO:0008147)
0.1 0.2 GO:0036004 GAF domain binding(GO:0036004)
0.1 0.2 GO:0004854 xanthine dehydrogenase activity(GO:0004854) oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor(GO:0016726)
0.1 0.3 GO:0008381 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.1 0.3 GO:0097001 ceramide binding(GO:0097001)
0.1 1.1 GO:0042288 MHC class I protein binding(GO:0042288)
0.0 1.2 GO:0071949 FAD binding(GO:0071949)
0.0 0.3 GO:0015091 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.0 0.5 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.1 GO:0016964 alpha-2 macroglobulin receptor activity(GO:0016964)
0.0 0.4 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0 0.4 GO:0046977 TAP binding(GO:0046977)
0.0 0.3 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.0 0.1 GO:0016743 carboxyl- or carbamoyltransferase activity(GO:0016743)
0.0 0.1 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.0 0.4 GO:1990405 protein antigen binding(GO:1990405)
0.0 0.1 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.0 4.5 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.1 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.0 0.2 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.0 0.3 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 1.0 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.1 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.0 0.3 GO:0042287 MHC protein binding(GO:0042287)
0.0 0.3 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.1 GO:0015056 corticotrophin-releasing factor receptor activity(GO:0015056) corticotropin-releasing hormone receptor activity(GO:0043404)
0.0 0.1 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.0 0.1 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.0 0.1 GO:0034481 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517) chondroitin sulfotransferase activity(GO:0034481)
0.0 0.2 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.1 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.0 0.1 GO:0070540 stearic acid binding(GO:0070540)
0.0 0.5 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.1 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.0 0.8 GO:0017171 serine hydrolase activity(GO:0017171)
0.0 0.1 GO:0070976 TIR domain binding(GO:0070976)
0.0 0.1 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.1 GO:0015205 purine nucleobase transmembrane transporter activity(GO:0005345) pyrimidine nucleobase transmembrane transporter activity(GO:0005350) nucleobase transmembrane transporter activity(GO:0015205) glycerol channel activity(GO:0015254)
0.0 0.1 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.0 0.1 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.2 GO:0042166 acetylcholine binding(GO:0042166)
0.0 1.1 GO:0019003 GDP binding(GO:0019003)
0.0 0.1 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.0 0.3 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.3 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.0 0.3 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 0.1 GO:0050733 RS domain binding(GO:0050733)
0.0 0.1 GO:0005000 vasopressin receptor activity(GO:0005000)
0.0 0.1 GO:0016936 galactoside binding(GO:0016936)
0.0 0.2 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 0.1 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.1 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.3 GO:0030247 pattern binding(GO:0001871) polysaccharide binding(GO:0030247)
0.0 0.1 GO:0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.0 0.1 GO:0051378 serotonin binding(GO:0051378)
0.0 0.0 GO:0000995 transcription factor activity, core RNA polymerase III binding(GO:0000995)
0.0 0.0 GO:0016979 lipoate-protein ligase activity(GO:0016979)
0.0 0.6 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.3 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.2 GO:0070330 aromatase activity(GO:0070330)
0.0 0.5 GO:0016860 intramolecular oxidoreductase activity(GO:0016860)
0.0 0.3 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 0.1 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.0 0.0 GO:0005333 norepinephrine transmembrane transporter activity(GO:0005333)
0.0 0.1 GO:0097643 amylin receptor activity(GO:0097643)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.3 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 2.0 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.5 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.7 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.6 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.7 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 0.2 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.6 PID IL3 PATHWAY IL3-mediated signaling events
0.0 0.4 PID MYC PATHWAY C-MYC pathway
0.0 0.4 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 0.3 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.5 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.5 PID CD40 PATHWAY CD40/CD40L signaling
0.0 0.2 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.2 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.1 PID ALK2 PATHWAY ALK2 signaling events
0.0 0.3 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.1 0.8 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.1 0.6 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 0.3 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.7 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.5 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.8 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.4 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.2 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 1.0 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 0.5 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.4 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.0 0.1 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.2 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.6 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.3 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.2 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.2 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.3 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 0.4 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 0.7 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.2 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.1 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.1 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 1.6 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.1 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.2 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.1 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins