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2D miR_HR1_12

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Results for GUGCAAA

Z-value: 1.15

Motif logo

miRNA associated with seed GUGCAAA

NamemiRBASE accession
MIMAT0000651
MIMAT0000513

Activity profile of GUGCAAA motif

Sorted Z-values of GUGCAAA motif

Promoter Log-likelihood Transcript Gene Gene Info
chr5_+_113735782 1.59 ENSMUST00000065698.5
FIC domain containing
chr12_-_119238794 1.49 ENSMUST00000026360.8
integrin beta 8
chr19_+_16956110 1.33 ENSMUST00000087689.4
prune homolog 2 (Drosophila)
chr5_-_93045022 1.18 ENSMUST00000061328.5
sosondowah ankyrin repeat domain family member B
chr4_-_53159885 1.12 ENSMUST00000030010.3
ATP-binding cassette, sub-family A (ABC1), member 1
chr11_+_61684419 1.09 ENSMUST00000093019.5
family with sequence similarity 83, member G
chr8_-_113848615 1.06 ENSMUST00000093113.4
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 18
chr2_+_118663235 1.05 ENSMUST00000099557.3
p21 protein (Cdc42/Rac)-activated kinase 6
chr5_+_64970069 1.05 ENSMUST00000031080.8
family with sequence similarity 114, member A1
chr17_+_44078813 0.95 ENSMUST00000154166.1
ENSMUST00000024756.4
ectonucleotide pyrophosphatase/phosphodiesterase 5
chr8_+_76899772 0.89 ENSMUST00000109913.2
nuclear receptor subfamily 3, group C, member 2
chr15_-_101054399 0.87 ENSMUST00000178140.1
fidgetin-like 2
chr10_+_34483400 0.87 ENSMUST00000019913.7
ENSMUST00000170771.1
fyn-related kinase
chr10_+_60277627 0.85 ENSMUST00000105465.1
ENSMUST00000177779.1
ENSMUST00000179238.1
ENSMUST00000004316.8
prosaposin
chr17_+_72918298 0.85 ENSMUST00000024857.6
limb-bud and heart
chr14_+_30715599 0.84 ENSMUST00000054230.4
Scm-like with four mbt domains 1
chr4_-_8239034 0.83 ENSMUST00000066674.7
carbonic anhydrase 8
chr1_+_60181495 0.83 ENSMUST00000160834.1
neurobeachin like 1
chr10_-_93311073 0.82 ENSMUST00000008542.5
ELK3, member of ETS oncogene family
chr6_-_72617000 0.82 ENSMUST00000070524.4
trans-golgi network protein
chr5_+_66968416 0.82 ENSMUST00000038188.7
LIM and calponin homology domains 1
chr19_+_38836561 0.81 ENSMUST00000037302.5
TBC1D12: TBC1 domain family, member 12
chr2_+_23068168 0.80 ENSMUST00000028121.7
ENSMUST00000114523.2
ENSMUST00000144088.1
acyl-Coenzyme A binding domain containing 5
chr13_-_13393592 0.80 ENSMUST00000021738.8
G protein-coupled receptor 137B
chr18_-_35215008 0.78 ENSMUST00000091636.3
leucine rich repeat transmembrane neuronal 2
chr16_+_33062512 0.77 ENSMUST00000023497.2
leishmanolysin-like (metallopeptidase M8 family)
chr9_-_117252450 0.76 ENSMUST00000111773.3
ENSMUST00000068962.7
ENSMUST00000044901.7
RNA binding motif, single stranded interacting protein
chr16_-_10785525 0.72 ENSMUST00000038099.4
suppressor of cytokine signaling 1
chr3_+_122729158 0.72 ENSMUST00000066728.5
phosphodiesterase 5A, cGMP-specific
chr14_+_45219993 0.71 ENSMUST00000146150.1
G protein-coupled receptor 137C
chr3_+_138065052 0.70 ENSMUST00000163080.2
RIKEN cDNA 1110002E22 gene
chr3_-_125938537 0.70 ENSMUST00000057944.7
UDP galactosyltransferase 8A
chr3_-_89387132 0.70 ENSMUST00000107433.1
zinc finger and BTB domain containing 7B
chrX_+_103356464 0.70 ENSMUST00000116547.2
cysteine-rich hydrophobic domain 1
chrX_-_162159717 0.69 ENSMUST00000087085.3
Nance-Horan syndrome (human)
chr14_-_72709986 0.69 ENSMUST00000089017.5
fibronectin type III domain containing 3A
chr11_+_70647258 0.68 ENSMUST00000037534.7
ring finger protein 167
chr5_-_67427794 0.67 ENSMUST00000169190.1
BEN domain containing 4
chr6_-_52204415 0.67 ENSMUST00000048794.6
homeobox A5
chr3_+_107101551 0.66 ENSMUST00000038695.1
potassium voltage-gated channel, shaker-related subfamily, member 2
chr10_-_109010955 0.66 ENSMUST00000105276.1
ENSMUST00000064054.7
synaptotagmin I
chr11_-_78697370 0.66 ENSMUST00000142739.1
nemo like kinase
chr4_+_33924632 0.65 ENSMUST00000057188.6
cannabinoid receptor 1 (brain)
chr7_-_109752210 0.62 ENSMUST00000128043.1
ENSMUST00000033333.6
TMEM9 domain family, member B
chr13_-_74807913 0.61 ENSMUST00000065629.4
calpastatin
chr6_-_5298455 0.61 ENSMUST00000057792.8
paraoxonase 2
chr1_-_126830632 0.61 ENSMUST00000112583.1
ENSMUST00000094609.3
NCK-associated protein 5
chr12_-_72408934 0.61 ENSMUST00000078505.7
reticulon 1
chr2_-_110362985 0.60 ENSMUST00000099626.3
fin bud initiation factor homolog (zebrafish)
chr6_+_118066356 0.59 ENSMUST00000164960.1
RasGEF domain family, member 1A
chr7_-_66388286 0.59 ENSMUST00000015277.7
leucine-rich repeat kinase 1
chr2_-_173276526 0.58 ENSMUST00000036248.6
prostate transmembrane protein, androgen induced 1
chr12_-_12941827 0.58 ENSMUST00000043396.7
v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)
chr15_+_99392882 0.57 ENSMUST00000023749.8
transmembrane BAX inhibitor motif containing 6
chr5_+_134099704 0.56 ENSMUST00000016088.8
GATS protein-like 2
chr11_+_44518959 0.56 ENSMUST00000019333.3
ring finger protein 145
chr2_+_145785980 0.55 ENSMUST00000110005.1
ENSMUST00000094480.4
Ras and Rab interactor 2
chr11_-_106160101 0.55 ENSMUST00000045923.3
LIM domain containing 2
chr7_-_68749170 0.53 ENSMUST00000118110.1
ENSMUST00000048068.7
arrestin domain containing 4
chr7_+_58658181 0.53 ENSMUST00000168747.1
ATPase, class V, type 10A
chr4_+_49059256 0.53 ENSMUST00000076670.2
RIKEN cDNA E130309F12 gene
chr5_+_19907502 0.53 ENSMUST00000101558.3
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr13_+_31625802 0.53 ENSMUST00000042054.2
forkhead box F2
chr9_-_43105718 0.52 ENSMUST00000165665.1
Rho guanine nucleotide exchange factor (GEF) 12
chr8_-_8660773 0.52 ENSMUST00000001319.7
ephrin B2
chr3_+_55112080 0.51 ENSMUST00000044116.7
ENSMUST00000107971.2
ENSMUST00000118118.1
spastic paraplegia 20, spartin (Troyer syndrome) homolog (human)
chr11_-_86807624 0.51 ENSMUST00000018569.7
DEAH (Asp-Glu-Ala-His) box polypeptide 40
chr14_-_20480106 0.51 ENSMUST00000065504.9
ENSMUST00000100844.4
annexin A7
chr16_-_74411292 0.51 ENSMUST00000117200.1
roundabout homolog 2 (Drosophila)
chrY_-_1286563 0.51 ENSMUST00000091190.5
DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
chr3_+_137867675 0.51 ENSMUST00000090178.5
DnaJ (Hsp40) homolog, subfamily B, member 14
chr10_-_78244602 0.50 ENSMUST00000000384.6
trafficking protein particle complex 10
chr11_+_117654798 0.50 ENSMUST00000106344.1
trinucleotide repeat containing 6C
chr6_+_72097561 0.50 ENSMUST00000069994.4
ENSMUST00000114112.1
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
chr2_+_19658055 0.49 ENSMUST00000052168.4
OTU domain containing 1
chr13_+_96542727 0.49 ENSMUST00000077672.4
ENSMUST00000109444.2
collagen, type IV, alpha 3 (Goodpasture antigen) binding protein
chr19_+_56722372 0.48 ENSMUST00000038949.4
adrenergic receptor, beta 1
chr10_-_110000219 0.48 ENSMUST00000032719.7
neuron navigator 3
chr4_-_151996113 0.48 ENSMUST00000055688.9
PHD finger protein 13
chr6_-_112947246 0.48 ENSMUST00000088373.4
SLIT-ROBO Rho GTPase activating protein 3
chr2_-_38287347 0.47 ENSMUST00000102787.3
DENN/MADD domain containing 1A
chr3_-_85746266 0.47 ENSMUST00000118408.1
family with sequence similarity 160, member A1
chr2_-_65238625 0.46 ENSMUST00000112429.2
ENSMUST00000102726.1
ENSMUST00000112430.1
Cobl-like 1
chr2_-_26092149 0.46 ENSMUST00000114159.2
nucleus accumbens associated 2, BEN and BTB (POZ) domain containing
chr1_+_118627943 0.46 ENSMUST00000027629.8
transcription factor CP2-like 1
chr6_+_108783059 0.45 ENSMUST00000032196.6
ADP-ribosylation factor-like 8B
chr3_-_108200807 0.45 ENSMUST00000106655.1
ENSMUST00000065664.6
cytochrome b-561 domain containing 1
chr10_-_123076367 0.45 ENSMUST00000073792.3
ENSMUST00000170935.1
ENSMUST00000037557.7
MON2 homolog (yeast)
chr7_-_112159034 0.44 ENSMUST00000033036.5
dickkopf homolog 3 (Xenopus laevis)
chr8_-_84147858 0.44 ENSMUST00000117424.2
ENSMUST00000040383.8
coiled-coil and C2 domain containing 1A
chr3_+_96181151 0.44 ENSMUST00000035371.8
synaptic vesicle glycoprotein 2 a
chr4_+_152096719 0.43 ENSMUST00000105661.3
ENSMUST00000084115.3
pleckstrin homology domain containing, family G (with RhoGef domain) member 5
chr4_-_109476666 0.43 ENSMUST00000030284.3
ring finger protein 11
chr3_-_59344256 0.43 ENSMUST00000039419.6
immunoglobulin superfamily, member 10
chr6_+_134830145 0.43 ENSMUST00000046303.5
cAMP responsive element binding protein-like 2
chr7_+_64287665 0.42 ENSMUST00000032736.4
myotubularin related protein 10
chr1_-_106796687 0.42 ENSMUST00000094646.5
vacuolar protein sorting 4b (yeast)
chr1_-_91931172 0.41 ENSMUST00000097644.2
histone deacetylase 4
chr2_+_106693185 0.41 ENSMUST00000111063.1
metallophosphoesterase domain containing 2
chr3_-_27710413 0.41 ENSMUST00000046157.4
fibronectin type III domain containing 3B
chr2_-_130840091 0.41 ENSMUST00000044766.8
ENSMUST00000138990.1
ENSMUST00000120316.1
ENSMUST00000110243.1
RIKEN cDNA 4930402H24 gene
chr8_-_83332416 0.41 ENSMUST00000177594.1
ENSMUST00000053902.3
ELMO/CED-12 domain containing 2
chr9_+_77917364 0.41 ENSMUST00000034904.7
ELOVL family member 5, elongation of long chain fatty acids (yeast)
chr11_-_47379405 0.41 ENSMUST00000077221.5
sarcoglycan, delta (dystrophin-associated glycoprotein)
chr18_-_38211957 0.41 ENSMUST00000159405.1
ENSMUST00000160721.1
protocadherin 1
chr3_+_51483966 0.40 ENSMUST00000054387.6
RAB33B, member of RAS oncogene family
chr14_-_24245913 0.40 ENSMUST00000073687.6
ENSMUST00000090398.4
discs, large homolog 5 (Drosophila)
chr16_+_11322876 0.40 ENSMUST00000180792.1
sorting nexin 29
chrX_+_101299143 0.40 ENSMUST00000118111.1
ENSMUST00000130555.1
ENSMUST00000151528.1
neuroligin 3
chr12_-_75177325 0.39 ENSMUST00000042299.2
potassium voltage-gated channel, subfamily H (eag-related), member 5
chr17_-_66077022 0.39 ENSMUST00000150766.1
ENSMUST00000038116.5
ankyrin repeat domain 12
chr18_+_77185815 0.39 ENSMUST00000079618.4
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5
chr5_+_91517615 0.39 ENSMUST00000040576.9
prostate androgen-regulated mucin-like protein 1
chr2_-_170131156 0.39 ENSMUST00000063710.6
zinc finger protein 217
chr3_+_32817520 0.38 ENSMUST00000072312.5
ENSMUST00000108228.1
ubiquitin specific peptidase 13 (isopeptidase T-3)
chr4_-_33248500 0.38 ENSMUST00000049357.9
proline-rich nuclear receptor coactivator 1
chr5_-_38561658 0.37 ENSMUST00000005234.9
WD repeat domain 1
chr12_+_82170016 0.37 ENSMUST00000166429.1
signal-induced proliferation-associated 1 like 1
chr10_+_42761483 0.37 ENSMUST00000019937.4
SEC63-like (S. cerevisiae)
chr4_+_135120640 0.37 ENSMUST00000056977.7
runt related transcription factor 3
chrX_+_23693043 0.37 ENSMUST00000035766.6
ENSMUST00000101670.2
WD repeat domain 44
chr7_+_27862557 0.37 ENSMUST00000053722.8
zinc finger proten 607
chr11_-_121354337 0.37 ENSMUST00000106110.3
ENSMUST00000136797.1
ENSMUST00000026173.6
WD repeat domain 45B
chr2_+_162931520 0.37 ENSMUST00000130411.1
serine/arginine-rich splicing factor 6
chr7_+_44310213 0.37 ENSMUST00000107938.1
SH3/ankyrin domain gene 1
chr3_-_103737995 0.37 ENSMUST00000029440.8
olfactomedin-like 3
chr7_+_4460687 0.36 ENSMUST00000167298.1
ENSMUST00000171445.1
EPS8-like 1
chr16_-_28929658 0.36 ENSMUST00000100023.1
Mab-21 domain containing 2
chr15_-_102136225 0.36 ENSMUST00000154032.1
SPRY domain containing 3
chr8_-_67974567 0.36 ENSMUST00000098696.3
ENSMUST00000038959.9
ENSMUST00000093469.4
pleckstrin and Sec7 domain containing 3
chr1_-_111864869 0.35 ENSMUST00000035462.5
dermatan sulfate epimerase-like
chr5_+_111417263 0.35 ENSMUST00000094463.4
meningioma 1
chr9_-_81633828 0.35 ENSMUST00000183482.1
5-hydroxytryptamine (serotonin) receptor 1B
chr6_+_143167210 0.35 ENSMUST00000032413.4
ethanolamine kinase 1
chr7_-_4658950 0.34 ENSMUST00000064099.6
protein phosphatase 6, regulatory subunit 1
chr12_+_84114321 0.34 ENSMUST00000123491.1
ENSMUST00000046340.2
ENSMUST00000136159.1
dynein, axonemal, light chain 1
chr15_-_86033777 0.34 ENSMUST00000016172.7
cadherin, EGF LAG seven-pass G-type receptor 1 (flamingo homolog, Drosophila)
chr17_-_51832666 0.34 ENSMUST00000144331.1
special AT-rich sequence binding protein 1
chr11_+_6546875 0.34 ENSMUST00000000388.8
cerebral cavernous malformation 2
chr1_+_105663855 0.34 ENSMUST00000086721.3
ENSMUST00000039173.6
RIKEN cDNA 2310035C23 gene
chr2_+_71981184 0.34 ENSMUST00000090826.5
ENSMUST00000102698.3
Rap guanine nucleotide exchange factor (GEF) 4
chr6_-_97148908 0.34 ENSMUST00000142116.1
ENSMUST00000113387.1
EGF domain-specific O-linked N-acetylglucosamine (GlcNAc) transferase
chr17_+_26715644 0.33 ENSMUST00000062519.7
ENSMUST00000144221.1
ENSMUST00000142539.1
ENSMUST00000151681.1
CREB3 regulatory factor
chr19_+_46599081 0.33 ENSMUST00000138302.2
ENSMUST00000099376.4
WW domain binding protein 1 like
chr14_-_70443442 0.33 ENSMUST00000000793.5
polymerase (RNA) III (DNA directed) polypeptide D
chr4_+_133369702 0.33 ENSMUST00000030669.7
solute carrier family 9 (sodium/hydrogen exchanger), member 1
chr4_+_133480126 0.33 ENSMUST00000051676.6
family with sequence similarity 46, member B
chr8_-_41133697 0.32 ENSMUST00000155055.1
ENSMUST00000059115.6
ENSMUST00000145860.1
mitochondrial tumor suppressor 1
chr8_-_34965631 0.32 ENSMUST00000033929.4
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
chr12_+_71831064 0.32 ENSMUST00000085299.2
dishevelled associated activator of morphogenesis 1
chr9_-_66919646 0.31 ENSMUST00000041139.7
RAB8B, member RAS oncogene family
chr4_-_119492563 0.31 ENSMUST00000049994.7
ribosomal modification protein rimK-like family member A
chr7_-_67372846 0.31 ENSMUST00000156690.1
ENSMUST00000107476.1
ENSMUST00000076325.5
ENSMUST00000032776.8
ENSMUST00000133074.1
myocyte enhancer factor 2A
chr2_-_118549668 0.31 ENSMUST00000090219.6
BCL2 modifying factor
chr7_-_47008397 0.31 ENSMUST00000061639.7
SPT2, Suppressor of Ty, domain containing 1 (S. cerevisiae)
chr13_+_97241096 0.31 ENSMUST00000041623.7
ectodermal-neural cortex 1
chr18_+_32163073 0.31 ENSMUST00000096575.3
mitogen-activated protein kinase kinase kinase 2
chr9_-_116175318 0.31 ENSMUST00000061101.4
ENSMUST00000035014.6
transforming growth factor, beta receptor II
chr5_+_101765120 0.31 ENSMUST00000031273.8
CDP-diacylglycerol synthase 1
chr2_+_154656959 0.30 ENSMUST00000044277.9
charged multivesicular body protein 4B
chr17_-_17624458 0.30 ENSMUST00000041047.2
leucyl/cystinyl aminopeptidase
chr12_-_54656496 0.30 ENSMUST00000056228.6
serine palmitoyltransferase, small subunit A
chr9_-_105495037 0.30 ENSMUST00000176190.1
ENSMUST00000163879.2
ENSMUST00000112558.2
ENSMUST00000176390.1
ATPase, Ca++-sequestering
chr8_+_12757002 0.30 ENSMUST00000033818.3
ENSMUST00000091237.5
ATPase, class VI, type 11A
chr17_+_73107982 0.30 ENSMUST00000130574.1
ENSMUST00000149064.1
ENSMUST00000067545.6
lysocardiolipin acyltransferase 1
chr5_-_124032214 0.30 ENSMUST00000040967.7
vacuolar protein sorting 37B (yeast)
chr17_-_27513341 0.29 ENSMUST00000118161.1
glutamate receptor, metabotropic 4
chr11_+_19924354 0.29 ENSMUST00000093299.6
sprouty-related, EVH1 domain containing 2
chr4_-_142239356 0.29 ENSMUST00000036476.3
kazrin, periplakin interacting protein
chr15_-_58214882 0.29 ENSMUST00000022986.6
F-box protein 32
chr6_+_49319274 0.28 ENSMUST00000055559.7
ENSMUST00000114491.1
coiled-coil domain containing 126
chr12_+_52516077 0.28 ENSMUST00000110725.1
Rho GTPase activating protein 5
chr1_+_55052770 0.28 ENSMUST00000027125.5
ENSMUST00000087617.4
coenzyme Q10 homolog B (S. cerevisiae)
chr2_-_73892530 0.28 ENSMUST00000136958.1
ENSMUST00000112010.2
ENSMUST00000128531.1
ENSMUST00000112017.1
activating transcription factor 2
chr8_+_88697022 0.28 ENSMUST00000043526.8
cylindromatosis (turban tumor syndrome)
chr2_+_155133501 0.28 ENSMUST00000029126.8
ENSMUST00000109685.1
itchy, E3 ubiquitin protein ligase
chr5_-_92083455 0.28 ENSMUST00000169094.1
ENSMUST00000167918.1
GTPase activating protein (SH3 domain) binding protein 2
chr1_-_93478785 0.28 ENSMUST00000170883.1
high density lipoprotein (HDL) binding protein
chr7_-_134938264 0.28 ENSMUST00000171394.1
family with sequence similarity 196, member A
chr7_-_25754701 0.28 ENSMUST00000108401.1
ENSMUST00000043765.7
heterogeneous nuclear ribonucleoprotein U-like 1
chr18_-_23041641 0.28 ENSMUST00000097651.3
nucleolar protein 4
chr2_+_74721978 0.27 ENSMUST00000047904.3
homeobox D3
chr2_-_132578155 0.27 ENSMUST00000110136.1
ENSMUST00000124107.1
ENSMUST00000060955.5
glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae)
chr11_-_20741447 0.27 ENSMUST00000177543.1
aftiphilin
chr10_-_128696257 0.27 ENSMUST00000000727.2
RAB5B, member RAS oncogene family
chr11_-_116086929 0.26 ENSMUST00000074628.6
ENSMUST00000106444.3
WW domain binding protein 2
chr19_+_11912389 0.26 ENSMUST00000061618.7
protein associated with topoisomerase II homolog 1 (yeast)
chr6_-_13677930 0.26 ENSMUST00000045235.5
RIKEN cDNA B630005N14 gene
chr8_-_36613937 0.26 ENSMUST00000033923.7
deleted in liver cancer 1
chr6_-_114921778 0.26 ENSMUST00000032459.7
vestigial like 4 (Drosophila)
chr2_-_30124454 0.26 ENSMUST00000044751.8
zyg-11 related, cell cycle regulator
chr16_+_52031549 0.25 ENSMUST00000114471.1
Casitas B-lineage lymphoma b
chr12_+_21111720 0.25 ENSMUST00000064595.8
ENSMUST00000101562.4
ENSMUST00000090834.6
ArfGAP with SH3 domain, ankyrin repeat and PH domain 2
chr13_+_48261427 0.25 ENSMUST00000021810.1
inhibitor of DNA binding 4
chr11_-_50292302 0.25 ENSMUST00000059458.4
mastermind like 1 (Drosophila)
chr15_-_38300693 0.25 ENSMUST00000074043.5
Kruppel-like factor 10
chr12_-_111377705 0.25 ENSMUST00000041965.3
CDC42 binding protein kinase beta
chr7_+_123123870 0.25 ENSMUST00000094053.5
trinucleotide repeat containing 6a
chr5_+_16553488 0.25 ENSMUST00000030683.3
hepatocyte growth factor
chr12_-_85339346 0.25 ENSMUST00000040992.7
NIMA (never in mitosis gene a)-related expressed kinase 9

Network of associatons between targets according to the STRING database.

First level regulatory network of GUGCAAA

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0031959 mineralocorticoid receptor signaling pathway(GO:0031959)
0.3 1.1 GO:0060155 response to high density lipoprotein particle(GO:0055099) platelet dense granule organization(GO:0060155)
0.2 0.7 GO:0060574 intestinal epithelial cell maturation(GO:0060574)
0.2 0.7 GO:0060282 positive regulation of chronic inflammatory response(GO:0002678) positive regulation of oocyte development(GO:0060282)
0.2 0.7 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.2 0.7 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.2 0.5 GO:0048698 negative regulation of collateral sprouting in absence of injury(GO:0048698)
0.2 0.5 GO:0009992 cellular water homeostasis(GO:0009992)
0.2 0.5 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
0.2 0.7 GO:0099553 trans-synaptic signaling by lipid, modulating synaptic transmission(GO:0099552) trans-synaptic signaling by endocannabinoid, modulating synaptic transmission(GO:0099553)
0.2 0.5 GO:0035621 ER to Golgi ceramide transport(GO:0035621) ceramide transport(GO:0035627)
0.2 0.5 GO:0001997 positive regulation of the force of heart contraction by epinephrine-norepinephrine(GO:0001997) positive regulation of the force of heart contraction by chemical signal(GO:0003099) positive regulation of renin secretion into blood stream(GO:1900135)
0.2 0.5 GO:1900477 negative regulation of G1/S transition of mitotic cell cycle by negative regulation of transcription from RNA polymerase II promoter(GO:1900477)
0.1 0.7 GO:0014877 response to inactivity(GO:0014854) response to muscle inactivity(GO:0014870) response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.1 0.4 GO:1903722 regulation of centriole elongation(GO:1903722)
0.1 0.4 GO:2000331 regulation of terminal button organization(GO:2000331)
0.1 0.4 GO:0044313 protein K6-linked deubiquitination(GO:0044313)
0.1 0.6 GO:2000065 negative regulation of aldosterone metabolic process(GO:0032345) negative regulation of aldosterone biosynthetic process(GO:0032348) negative regulation of cortisol biosynthetic process(GO:2000065)
0.1 0.8 GO:0002666 positive regulation of T cell tolerance induction(GO:0002666)
0.1 0.3 GO:0060490 orthogonal dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060488) planar dichotomous subdivision of terminal units involved in lung branching morphogenesis(GO:0060489) lateral sprouting involved in lung morphogenesis(GO:0060490)
0.1 0.8 GO:0030242 pexophagy(GO:0030242)
0.1 0.6 GO:0031438 regulation of mRNA cleavage(GO:0031437) negative regulation of mRNA cleavage(GO:0031438) regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904720) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
0.1 0.7 GO:0021631 optic nerve morphogenesis(GO:0021631)
0.1 0.3 GO:1903279 regulation of calcium:sodium antiporter activity(GO:1903279)
0.1 0.3 GO:0090650 response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.1 0.9 GO:1904672 regulation of somatic stem cell population maintenance(GO:1904672)
0.1 0.3 GO:1904742 regulation of telomeric DNA binding(GO:1904742)
0.1 0.3 GO:0070375 ERK5 cascade(GO:0070375)
0.1 0.3 GO:0046341 CDP-diacylglycerol metabolic process(GO:0046341)
0.1 0.3 GO:0090611 ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611)
0.1 0.4 GO:0045054 constitutive secretory pathway(GO:0045054)
0.1 0.1 GO:1901563 response to camptothecin(GO:1901563)
0.1 0.3 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.1 0.4 GO:0030043 actin filament fragmentation(GO:0030043)
0.1 0.7 GO:0010533 regulation of activation of Janus kinase activity(GO:0010533)
0.1 0.5 GO:1903847 regulation of aorta morphogenesis(GO:1903847) positive regulation of aorta morphogenesis(GO:1903849)
0.1 0.2 GO:0071963 establishment or maintenance of cell polarity regulating cell shape(GO:0071963)
0.1 0.1 GO:0048696 regulation of collateral sprouting in absence of injury(GO:0048696)
0.1 0.3 GO:1904457 positive regulation of neuronal action potential(GO:1904457)
0.1 0.3 GO:0003162 atrioventricular node development(GO:0003162)
0.1 0.6 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.1 0.2 GO:1902512 positive regulation of apoptotic DNA fragmentation(GO:1902512)
0.1 0.5 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.1 0.3 GO:0010847 regulation of chromatin assembly(GO:0010847)
0.1 0.3 GO:0010499 proteasomal ubiquitin-independent protein catabolic process(GO:0010499)
0.1 0.2 GO:1900248 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
0.1 0.3 GO:0055071 cellular manganese ion homeostasis(GO:0030026) Golgi calcium ion homeostasis(GO:0032468) manganese ion homeostasis(GO:0055071)
0.1 0.1 GO:1902263 apoptotic process involved in embryonic digit morphogenesis(GO:1902263)
0.1 1.1 GO:0090331 negative regulation of platelet aggregation(GO:0090331)
0.1 0.3 GO:0030205 dermatan sulfate metabolic process(GO:0030205)
0.1 0.3 GO:0097343 ripoptosome assembly(GO:0097343) ripoptosome assembly involved in necroptotic process(GO:1901026)
0.1 0.3 GO:0007198 adenylate cyclase-inhibiting serotonin receptor signaling pathway(GO:0007198) negative regulation of serotonin secretion(GO:0014063) cellular response to temperature stimulus(GO:0071502)
0.1 0.4 GO:0072205 metanephric collecting duct development(GO:0072205)
0.1 1.4 GO:0001573 ganglioside metabolic process(GO:0001573)
0.1 0.4 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.1 0.7 GO:0005513 detection of calcium ion(GO:0005513)
0.1 0.1 GO:1904349 positive regulation of small intestine smooth muscle contraction(GO:1904349)
0.1 0.1 GO:0045415 negative regulation of interleukin-8 biosynthetic process(GO:0045415)
0.1 0.1 GO:0032472 Golgi calcium ion transport(GO:0032472)
0.1 0.2 GO:0017187 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.1 0.2 GO:0060599 positive regulation of integrin biosynthetic process(GO:0045726) lateral sprouting involved in mammary gland duct morphogenesis(GO:0060599) tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.1 0.5 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.1 0.2 GO:0071211 protein targeting to vacuole involved in autophagy(GO:0071211)
0.1 0.3 GO:0032915 positive regulation of transforming growth factor beta2 production(GO:0032915)
0.1 0.3 GO:0038161 prolactin signaling pathway(GO:0038161) negative regulation of glucocorticoid mediated signaling pathway(GO:1900170)
0.1 0.4 GO:0014052 regulation of gamma-aminobutyric acid secretion(GO:0014052)
0.1 0.2 GO:0090327 negative regulation of locomotion involved in locomotory behavior(GO:0090327)
0.1 0.2 GO:1902953 positive regulation of ER to Golgi vesicle-mediated transport(GO:1902953) positive regulation of endocytic recycling(GO:2001137)
0.1 0.5 GO:0007343 egg activation(GO:0007343)
0.1 0.2 GO:0014707 branchiomeric skeletal muscle development(GO:0014707)
0.1 0.3 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
0.1 0.2 GO:0070318 positive regulation of G0 to G1 transition(GO:0070318)
0.1 0.2 GO:0044565 dendritic cell proliferation(GO:0044565)
0.1 0.3 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.0 0.1 GO:0090076 relaxation of skeletal muscle(GO:0090076)
0.0 0.3 GO:0001957 intramembranous ossification(GO:0001957) direct ossification(GO:0036072)
0.0 0.2 GO:1905161 protein localization to phagocytic vesicle(GO:1905161) regulation of protein localization to phagocytic vesicle(GO:1905169) positive regulation of protein localization to phagocytic vesicle(GO:1905171)
0.0 0.2 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.0 0.4 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 0.9 GO:0060742 epithelial cell differentiation involved in prostate gland development(GO:0060742)
0.0 0.5 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.4 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
0.0 0.1 GO:0035973 aggrephagy(GO:0035973)
0.0 0.4 GO:0002070 epithelial cell maturation(GO:0002070)
0.0 0.3 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
0.0 0.2 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.0 0.5 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.3 GO:0007196 adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway(GO:0007196)
0.0 0.2 GO:0032290 peripheral nervous system myelin formation(GO:0032290)
0.0 0.7 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 0.8 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.2 GO:0001830 trophectodermal cell fate commitment(GO:0001830)
0.0 0.6 GO:0036035 osteoclast development(GO:0036035)
0.0 0.3 GO:0045046 peroxisomal membrane transport(GO:0015919) protein import into peroxisome membrane(GO:0045046)
0.0 0.3 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
0.0 0.3 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.9 GO:0048712 negative regulation of astrocyte differentiation(GO:0048712)
0.0 0.3 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.0 0.2 GO:0099525 presynaptic dense core granule exocytosis(GO:0099525)
0.0 0.4 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.4 GO:0046959 habituation(GO:0046959)
0.0 0.1 GO:2000537 signal complex assembly(GO:0007172) regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538)
0.0 0.2 GO:0015676 vanadium ion transport(GO:0015676) lead ion transport(GO:0015692)
0.0 0.5 GO:0040033 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0 0.1 GO:0090285 negative regulation of protein glycosylation in Golgi(GO:0090285)
0.0 0.2 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
0.0 0.5 GO:0042249 establishment of planar polarity of embryonic epithelium(GO:0042249)
0.0 0.2 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.0 0.1 GO:1900126 negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.0 0.2 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.0 0.5 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.0 0.2 GO:0071481 cellular response to X-ray(GO:0071481)
0.0 0.4 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.0 0.1 GO:0023016 signal transduction by trans-phosphorylation(GO:0023016)
0.0 0.4 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.0 0.2 GO:0097324 melanocyte migration(GO:0097324)
0.0 0.4 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.1 GO:0019085 early viral transcription(GO:0019085)
0.0 0.3 GO:0060837 blood vessel endothelial cell differentiation(GO:0060837)
0.0 0.2 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.0 0.2 GO:0015705 iodide transport(GO:0015705)
0.0 0.7 GO:0060009 Sertoli cell development(GO:0060009)
0.0 0.4 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.2 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.0 0.2 GO:0045634 regulation of melanocyte differentiation(GO:0045634)
0.0 1.0 GO:2000785 regulation of autophagosome assembly(GO:2000785)
0.0 0.4 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 0.9 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.0 0.1 GO:0035509 negative regulation of myosin-light-chain-phosphatase activity(GO:0035509)
0.0 0.6 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.1 GO:0033030 negative regulation of neutrophil apoptotic process(GO:0033030)
0.0 0.2 GO:1902947 regulation of tau-protein kinase activity(GO:1902947)
0.0 0.3 GO:0072501 cellular phosphate ion homeostasis(GO:0030643) cellular divalent inorganic anion homeostasis(GO:0072501) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0 0.7 GO:0051443 positive regulation of ubiquitin-protein transferase activity(GO:0051443)
0.0 0.1 GO:0035434 copper ion transmembrane transport(GO:0035434)
0.0 0.0 GO:0021797 forebrain anterior/posterior pattern specification(GO:0021797)
0.0 0.3 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 0.3 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 0.2 GO:0035878 nail development(GO:0035878)
0.0 0.6 GO:0042501 serine phosphorylation of STAT protein(GO:0042501)
0.0 0.1 GO:2000074 response to redox state(GO:0051775) regulation of type B pancreatic cell development(GO:2000074)
0.0 0.0 GO:0016332 establishment or maintenance of polarity of embryonic epithelium(GO:0016332)
0.0 0.3 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.0 0.1 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.1 GO:2000664 positive regulation of interleukin-5 secretion(GO:2000664) positive regulation of interleukin-13 secretion(GO:2000667)
0.0 0.5 GO:0002091 negative regulation of receptor internalization(GO:0002091)
0.0 0.1 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 0.1 GO:0032485 regulation of Ral protein signal transduction(GO:0032485)
0.0 0.2 GO:1903337 positive regulation of vacuolar transport(GO:1903337) positive regulation of early endosome to late endosome transport(GO:2000643)
0.0 0.2 GO:0043162 ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043162)
0.0 0.3 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.0 0.1 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.0 0.3 GO:0006744 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.0 0.4 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.0 0.1 GO:0060510 Type II pneumocyte differentiation(GO:0060510)
0.0 0.3 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.1 GO:0090214 spongiotrophoblast layer developmental growth(GO:0090214)
0.0 0.1 GO:1902035 positive regulation of hematopoietic stem cell proliferation(GO:1902035)
0.0 0.8 GO:0015914 phospholipid transport(GO:0015914)
0.0 0.2 GO:0031424 keratinization(GO:0031424)
0.0 0.3 GO:0031069 hair follicle morphogenesis(GO:0031069)
0.0 0.2 GO:0060252 positive regulation of glial cell proliferation(GO:0060252)
0.0 0.4 GO:0035767 endothelial cell chemotaxis(GO:0035767)
0.0 0.2 GO:0071786 endoplasmic reticulum tubular network organization(GO:0071786)
0.0 0.1 GO:0006983 ER overload response(GO:0006983)
0.0 0.2 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.1 GO:0071044 histone mRNA catabolic process(GO:0071044)
0.0 0.1 GO:0044821 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.0 0.1 GO:0010989 negative regulation of lipoprotein particle clearance(GO:0010985) negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.0 0.3 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.0 0.4 GO:0042246 tissue regeneration(GO:0042246)
0.0 0.5 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.0 0.9 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.0 0.3 GO:0010758 regulation of macrophage chemotaxis(GO:0010758)
0.0 0.2 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.0 GO:0016240 autophagosome docking(GO:0016240)
0.0 0.4 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.0 0.1 GO:2001199 negative regulation of monocyte differentiation(GO:0045656) negative regulation of dendritic cell differentiation(GO:2001199)
0.0 0.1 GO:0061088 sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0042584 chromaffin granule membrane(GO:0042584)
0.1 0.4 GO:0097447 dendritic tree(GO:0097447)
0.1 0.3 GO:0044316 cone cell pedicle(GO:0044316)
0.1 0.2 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.1 0.3 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.1 0.4 GO:0016012 sarcoglycan complex(GO:0016012)
0.1 0.2 GO:0016939 kinesin II complex(GO:0016939)
0.1 0.4 GO:0005796 Golgi lumen(GO:0005796)
0.1 0.2 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.1 0.5 GO:0000813 ESCRT I complex(GO:0000813)
0.1 0.7 GO:0061700 GATOR2 complex(GO:0061700)
0.1 0.2 GO:0098831 presynaptic active zone cytoplasmic component(GO:0098831)
0.1 0.3 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 1.4 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.1 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.0 0.2 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559)
0.0 0.1 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.0 0.3 GO:0031211 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.8 GO:0031045 dense core granule(GO:0031045)
0.0 1.7 GO:0008305 integrin complex(GO:0008305)
0.0 0.2 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.2 GO:0070826 paraferritin complex(GO:0070826)
0.0 0.1 GO:0005940 septin ring(GO:0005940)
0.0 0.7 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.3 GO:0090533 cation-transporting ATPase complex(GO:0090533)
0.0 0.4 GO:0090543 Flemming body(GO:0090543)
0.0 0.5 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.5 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.4 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.3 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.0 0.3 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.5 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.2 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.0 0.3 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.3 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 0.2 GO:0031313 extrinsic component of vacuolar membrane(GO:0000306) extrinsic component of endosome membrane(GO:0031313)
0.0 0.2 GO:0089701 U2AF(GO:0089701)
0.0 0.7 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.2 GO:0071203 WASH complex(GO:0071203)
0.0 0.3 GO:0097542 ciliary tip(GO:0097542)
0.0 0.2 GO:0030314 junctional membrane complex(GO:0030314)
0.0 0.3 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0 0.1 GO:0005726 perichromatin fibrils(GO:0005726)
0.0 0.2 GO:0001533 cornified envelope(GO:0001533)
0.0 0.5 GO:0051233 spindle midzone(GO:0051233)
0.0 0.3 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 0.2 GO:0005641 nuclear envelope lumen(GO:0005641) low-density lipoprotein particle(GO:0034362)
0.0 0.0 GO:0016011 dystroglycan complex(GO:0016011)
0.0 0.1 GO:0097427 microtubule bundle(GO:0097427)
0.0 0.4 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.3 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.3 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.1 GO:0097165 nuclear stress granule(GO:0097165)
0.0 0.4 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.1 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.2 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.5 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 1.5 GO:0042641 actomyosin(GO:0042641)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0090556 apolipoprotein receptor activity(GO:0030226) apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.3 0.9 GO:0017082 mineralocorticoid receptor activity(GO:0017082)
0.2 1.5 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.2 0.8 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.2 0.6 GO:0046573 lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
0.2 0.9 GO:0004565 beta-galactosidase activity(GO:0004565)
0.2 0.7 GO:0030348 syntaxin-3 binding(GO:0030348)
0.2 0.7 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.2 0.5 GO:0051380 norepinephrine binding(GO:0051380)
0.1 0.3 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.1 0.5 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
0.1 0.3 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.1 0.6 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.1 0.4 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.1 0.5 GO:0097001 ceramide binding(GO:0097001)
0.1 0.3 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.1 0.4 GO:1904288 BAT3 complex binding(GO:1904288)
0.1 0.3 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1 0.3 GO:0015410 manganese-transporting ATPase activity(GO:0015410)
0.1 0.7 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.1 0.3 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.1 0.4 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.1 0.3 GO:0001642 group III metabotropic glutamate receptor activity(GO:0001642)
0.1 0.3 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.1 0.4 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.1 0.2 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.1 0.9 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.1 1.2 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.3 GO:0004305 ethanolamine kinase activity(GO:0004305)
0.0 0.1 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.0 0.8 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.2 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.0 0.1 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.3 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.3 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 1.6 GO:0070566 adenylyltransferase activity(GO:0070566)
0.0 0.3 GO:0048039 ubiquinone binding(GO:0048039)
0.0 0.4 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.0 0.9 GO:0004551 nucleotide diphosphatase activity(GO:0004551)
0.0 0.1 GO:0030350 iron-responsive element binding(GO:0030350)
0.0 0.3 GO:0030911 TPR domain binding(GO:0030911)
0.0 0.4 GO:0102336 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.2 GO:0015639 cadmium ion transmembrane transporter activity(GO:0015086) lead ion transmembrane transporter activity(GO:0015094) vanadium ion transmembrane transporter activity(GO:0015100) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.0 0.1 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.0 0.2 GO:0038132 neuregulin binding(GO:0038132)
0.0 0.2 GO:0031493 nucleosomal histone binding(GO:0031493)
0.0 0.7 GO:0047555 3',5'-cyclic-GMP phosphodiesterase activity(GO:0047555)
0.0 0.4 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.8 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.6 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.1 GO:0086008 voltage-gated potassium channel activity involved in cardiac muscle cell action potential repolarization(GO:0086008)
0.0 0.3 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993) serotonin binding(GO:0051378)
0.0 0.2 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.2 GO:0070883 pre-miRNA binding(GO:0070883)
0.0 0.2 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
0.0 1.0 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.3 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.3 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.1 GO:0004566 beta-glucuronidase activity(GO:0004566)
0.0 0.1 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 0.2 GO:0000182 rDNA binding(GO:0000182)
0.0 0.2 GO:0019870 potassium channel inhibitor activity(GO:0019870)
0.0 0.3 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.2 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.0 0.1 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0 0.7 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.1 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.0 0.7 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.4 GO:0017166 vinculin binding(GO:0017166)
0.0 0.3 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.2 GO:0019992 diacylglycerol binding(GO:0019992)
0.0 0.3 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0 0.1 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.2 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.4 GO:0042608 T cell receptor binding(GO:0042608)
0.0 0.9 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.4 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.5 GO:0008373 sialyltransferase activity(GO:0008373)
0.0 0.9 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 1.9 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.3 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 0.7 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.1 GO:0005375 copper ion transmembrane transporter activity(GO:0005375)
0.0 0.1 GO:0008142 oxysterol binding(GO:0008142)
0.0 0.2 GO:0048038 quinone binding(GO:0048038)
0.0 0.2 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.3 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.1 GO:0008440 inositol-1,4,5-trisphosphate 3-kinase activity(GO:0008440)
0.0 0.3 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 0.9 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 0.5 GO:0004407 histone deacetylase activity(GO:0004407)
0.0 0.1 GO:0045322 double-stranded methylated DNA binding(GO:0010385) unmethylated CpG binding(GO:0045322)
0.0 0.1 GO:0046790 virion binding(GO:0046790)
0.0 2.3 GO:0005088 Ras guanyl-nucleotide exchange factor activity(GO:0005088)
0.0 0.7 GO:0017048 Rho GTPase binding(GO:0017048)
0.0 0.1 GO:0097322 7SK snRNA binding(GO:0097322)
0.0 0.2 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.5 GO:0003785 actin monomer binding(GO:0003785)
0.0 1.0 GO:0003724 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004)
0.0 0.3 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.0 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.0 0.3 GO:0042605 peptide antigen binding(GO:0042605)
0.0 0.2 GO:0016208 AMP binding(GO:0016208)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.1 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 0.3 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 0.3 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.4 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.0 1.0 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 1.0 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 1.0 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.6 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.2 PID CXCR4 PATHWAY CXCR4-mediated signaling events
0.0 0.1 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.4 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.3 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.9 PID IFNG PATHWAY IFN-gamma pathway
0.0 0.3 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.2 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.5 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.5 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 0.4 PID CD40 PATHWAY CD40/CD40L signaling
0.0 0.2 ST ADRENERGIC Adrenergic Pathway
0.0 0.7 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 0.6 PID RHOA PATHWAY RhoA signaling pathway
0.0 0.4 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.3 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.6 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 1.0 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.1 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.0 0.4 PID FOXO PATHWAY FoxO family signaling
0.0 0.2 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 0.2 PID EPO PATHWAY EPO signaling pathway
0.0 0.3 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.1 1.0 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.1 0.9 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.1 0.7 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.1 1.1 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.5 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 1.0 REACTOME REGULATORY RNA PATHWAYS Genes involved in Regulatory RNA pathways
0.0 1.0 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.3 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.3 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.9 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.0 0.5 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.5 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.4 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.9 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 1.1 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.5 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.7 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.5 REACTOME ENERGY DEPENDENT REGULATION OF MTOR BY LKB1 AMPK Genes involved in Energy dependent regulation of mTOR by LKB1-AMPK
0.0 0.3 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.3 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.4 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 1.9 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.2 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.6 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.3 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.5 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.3 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.3 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.1 REACTOME GPVI MEDIATED ACTIVATION CASCADE Genes involved in GPVI-mediated activation cascade
0.0 0.2 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.4 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 0.1 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.1 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.2 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression