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2D miR_HR1_12

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Results for Foxn1

Z-value: 0.39

Motif logo

Transcription factors associated with Foxn1

Gene Symbol Gene ID Gene Info
ENSMUSG00000002057.4 forkhead box N1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Foxn1mm10_v2_chr11_-_78386558_783865980.195.6e-01Click!

Activity profile of Foxn1 motif

Sorted Z-values of Foxn1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr4_-_40722307 0.71 ENSMUST00000181475.1
predicted gene 6297
chr9_+_72985504 0.52 ENSMUST00000156879.1
cell cycle progression 1
chr15_-_101054399 0.48 ENSMUST00000178140.1
fidgetin-like 2
chr3_+_89418443 0.47 ENSMUST00000039110.5
ENSMUST00000125036.1
ENSMUST00000154791.1
ENSMUST00000128238.1
ENSMUST00000107417.2
src homology 2 domain-containing transforming protein C1
chr13_-_64274879 0.44 ENSMUST00000109770.1
CDC14 cell division cycle 14B
chr1_+_59119822 0.43 ENSMUST00000180570.1
RIKEN cDNA G730003C15 gene
chr9_+_72985410 0.42 ENSMUST00000037977.8
cell cycle progression 1
chr13_-_64274962 0.41 ENSMUST00000039318.8
CDC14 cell division cycle 14B
chr9_+_72985568 0.38 ENSMUST00000150826.2
ENSMUST00000085350.4
ENSMUST00000140675.1
cell cycle progression 1
chr19_+_45363734 0.38 ENSMUST00000065601.5
ENSMUST00000111936.2
beta-transducin repeat containing protein
chr7_+_133776857 0.34 ENSMUST00000065359.5
ENSMUST00000151031.1
ENSMUST00000121560.1
fibronectin type 3 and ankyrin repeat domains 1
chr1_+_95313607 0.32 ENSMUST00000059975.6
family with sequence similarity 174, member A
chr11_-_103363431 0.30 ENSMUST00000092557.5
Rho GTPase activating protein 27
chr11_+_103116228 0.30 ENSMUST00000053063.5
hexamethylene bis-acetamide inducible 1
chr8_-_111876661 0.30 ENSMUST00000034431.1
transmembrane protein 170
chr10_-_7681118 0.30 ENSMUST00000159977.1
ENSMUST00000162682.1
protein-L-isoaspartate (D-aspartate) O-methyltransferase 1
chr9_-_72985344 0.30 ENSMUST00000124565.2
predicted gene 5918
chr2_-_163645125 0.28 ENSMUST00000017851.3
serine incorporator 3
chr9_-_21592805 0.27 ENSMUST00000034700.7
ENSMUST00000180365.1
ENSMUST00000078572.7
Yip1 domain family, member 2
chr7_-_27396542 0.27 ENSMUST00000108363.1
spectrin beta, non-erythrocytic 4
chr17_-_80373541 0.25 ENSMUST00000086549.1
predicted gene 10190
chr1_-_155099630 0.23 ENSMUST00000055322.4
immediate early response 5
chr4_-_147936713 0.23 ENSMUST00000105712.1
ENSMUST00000019199.7
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 1
chr8_+_105636509 0.22 ENSMUST00000005841.9
CCCTC-binding factor
chr13_+_77135513 0.22 ENSMUST00000168779.1
RIKEN cDNA 2210408I21 gene
chr7_+_19004047 0.22 ENSMUST00000053713.3
interferon regulatory factor 2 binding protein 1
chrX_+_99136119 0.21 ENSMUST00000052839.6
ephrin B1
chr18_-_37935378 0.21 ENSMUST00000025337.7
diaphanous homolog 1 (Drosophila)
chr19_-_36919606 0.21 ENSMUST00000057337.7
fibroblast growth factor binding protein 3
chr1_+_127868773 0.21 ENSMUST00000037649.5
RAB3 GTPase activating protein subunit 1
chr10_+_19934472 0.20 ENSMUST00000095806.3
ENSMUST00000120259.1
mitogen-activated protein kinase kinase kinase 5
chr7_-_127588595 0.19 ENSMUST00000072155.3
predicted gene 166
chr19_+_46152505 0.19 ENSMUST00000026254.7
golgi-specific brefeldin A-resistance factor 1
chr7_-_25297866 0.18 ENSMUST00000148150.1
ENSMUST00000155118.1
platelet-activating factor acetylhydrolase, isoform 1b, subunit 3
chr5_+_130171798 0.18 ENSMUST00000119797.1
ENSMUST00000148264.1
RAB guanine nucleotide exchange factor (GEF) 1
chr2_+_131210363 0.18 ENSMUST00000110210.1
ENSMUST00000089506.5
ENSMUST00000110208.1
adaptor-related protein 5 complex, sigma 1 subunit
chr8_-_11008458 0.18 ENSMUST00000040514.6
insulin receptor substrate 2
chr8_-_94012558 0.18 ENSMUST00000053766.6
autocrine motility factor receptor
chr3_-_116007399 0.18 ENSMUST00000067485.3
solute carrier family 30 (zinc transporter), member 7
chr11_-_50210765 0.18 ENSMUST00000143379.1
ENSMUST00000015981.5
ENSMUST00000102774.4
sequestosome 1
chr7_-_100371889 0.18 ENSMUST00000032963.8
protein phosphatase methylesterase 1
chr9_-_64737684 0.17 ENSMUST00000171100.1
ENSMUST00000167569.1
ENSMUST00000004892.6
ENSMUST00000172298.1
RAB11a, member RAS oncogene family
chr17_-_29237759 0.17 ENSMUST00000137727.1
ENSMUST00000024805.7
copine V
chr7_-_25297967 0.17 ENSMUST00000005583.5
platelet-activating factor acetylhydrolase, isoform 1b, subunit 3
chr9_-_119578981 0.16 ENSMUST00000117911.1
ENSMUST00000120420.1
sodium channel, voltage-gated, type V, alpha
chr14_-_57746044 0.16 ENSMUST00000173990.1
ENSMUST00000022531.7
large tumor suppressor 2
chr2_+_131210501 0.16 ENSMUST00000110206.1
adaptor-related protein 5 complex, sigma 1 subunit
chr13_-_95223045 0.16 ENSMUST00000162292.1
phosphodiesterase 8B
chr4_+_122836236 0.16 ENSMUST00000030412.4
ENSMUST00000121870.1
ENSMUST00000097902.4
palmitoyl-protein thioesterase 1
chr6_+_38433913 0.16 ENSMUST00000160583.1
ubinuclein 2
chr3_+_116007457 0.15 ENSMUST00000029575.5
ENSMUST00000106501.1
exostoses (multiple)-like 2
chr8_-_83332416 0.15 ENSMUST00000177594.1
ENSMUST00000053902.3
ELMO/CED-12 domain containing 2
chr9_-_64737623 0.14 ENSMUST00000169058.1
RAB11a, member RAS oncogene family
chr7_+_25267669 0.13 ENSMUST00000169266.1
capicua homolog (Drosophila)
chr12_+_86082555 0.12 ENSMUST00000054565.6
intraflagellar transport 43 homolog (Chlamydomonas)
chr17_-_57031468 0.11 ENSMUST00000007814.8
KH-type splicing regulatory protein
chrX_+_151803313 0.11 ENSMUST00000026292.8
HECT, UBA and WWE domain containing 1
chr8_-_94012120 0.11 ENSMUST00000143265.1
autocrine motility factor receptor
chr1_-_161876656 0.11 ENSMUST00000048377.5
SUN domain containing ossification factor
chr6_+_149408973 0.10 ENSMUST00000086829.4
ENSMUST00000111513.2
bicaudal D homolog 1 (Drosophila)
chr18_-_10610048 0.10 ENSMUST00000115864.1
establishment of cohesion 1 homolog 1 (S. cerevisiae)
chr4_+_40722461 0.10 ENSMUST00000030118.3
DnaJ (Hsp40) homolog, subfamily A, member 1
chr1_+_178405881 0.10 ENSMUST00000027775.7
EF-hand calcium binding domain 2
chr4_+_116557658 0.10 ENSMUST00000030460.8
GC-rich promoter binding protein 1-like 1
chr11_+_93996082 0.10 ENSMUST00000041956.7
sperm associated antigen 9
chr16_-_96082513 0.10 ENSMUST00000113827.1
bromodomain and WD repeat domain containing 1
chr12_+_105685352 0.10 ENSMUST00000051934.5
GSK3B interacting protein
chr11_-_70239794 0.10 ENSMUST00000040428.3
ribonuclease, RNase K
chr17_+_86963279 0.10 ENSMUST00000139344.1
ras homolog gene family, member Q
chr7_+_127588698 0.09 ENSMUST00000033088.6
ring finger protein 40
chr19_+_43612299 0.09 ENSMUST00000057178.9
NK2 homeobox 3
chr4_+_116558056 0.09 ENSMUST00000106475.1
GC-rich promoter binding protein 1-like 1
chr9_-_75683992 0.09 ENSMUST00000034699.6
secretogranin III
chr15_+_81872309 0.08 ENSMUST00000023116.6
aconitase 2, mitochondrial
chr8_-_72571033 0.08 ENSMUST00000058733.8
ENSMUST00000167290.1
small integral membrane protein 7
chrX_+_7841800 0.08 ENSMUST00000033494.9
ENSMUST00000115666.1
OTU domain containing 5
chr2_-_127788854 0.08 ENSMUST00000028857.7
ENSMUST00000110357.1
nephronophthisis 1 (juvenile) homolog (human)
chr9_+_70207342 0.07 ENSMUST00000034745.7
myosin IE
chr16_-_96082389 0.07 ENSMUST00000099502.2
ENSMUST00000023631.8
ENSMUST00000113829.1
ENSMUST00000153398.1
bromodomain and WD repeat domain containing 1
chr11_-_69758630 0.07 ENSMUST00000058470.9
polymerase (RNA) II (DNA directed) polypeptide A
chr3_+_103020546 0.07 ENSMUST00000029446.8
cold shock domain containing E1, RNA binding
chr11_+_67455339 0.07 ENSMUST00000108681.1
growth arrest specific 7
chr14_+_63606491 0.06 ENSMUST00000119973.2
X Kell blood group precursor related family member 6 homolog
chr17_+_6106464 0.06 ENSMUST00000142030.1
tubby like protein 4
chrX_-_74085586 0.06 ENSMUST00000123362.1
ENSMUST00000140399.1
ENSMUST00000100750.3
methyl CpG binding protein 2
chr2_+_153492790 0.05 ENSMUST00000109783.1
RIKEN cDNA 4930404H24 gene
chr2_+_125859134 0.05 ENSMUST00000028636.6
ENSMUST00000125084.1
galactokinase 2
chr9_+_69989466 0.05 ENSMUST00000034754.5
ENSMUST00000085393.6
ENSMUST00000117450.1
BCL2/adenovirus E1B interacting protein 2
chr2_-_28583189 0.05 ENSMUST00000113889.2
general transcription factor IIIC, polypeptide 5
chr7_+_100372224 0.04 ENSMUST00000051777.8
ENSMUST00000098259.4
C2 calcium-dependent domain containing 3
chr11_+_88068242 0.04 ENSMUST00000018521.4
vascular endothelial zinc finger 1
chr14_+_111675113 0.04 ENSMUST00000042767.7
SLIT and NTRK-like family, member 5
chr17_-_36951338 0.04 ENSMUST00000173540.1
protein phosphatase 1, regulatory (inhibitor) subunit 11
chr18_-_46525940 0.04 ENSMUST00000036226.5
fem-1 homolog c (C.elegans)
chr4_-_121215071 0.03 ENSMUST00000056635.5
rearranged L-myc fusion sequence
chr6_-_85374606 0.03 ENSMUST00000060837.7
RAB11 family interacting protein 5 (class I)
chr17_-_80062333 0.03 ENSMUST00000061331.7
heterogeneous nuclear ribonucleoprotein L-like
chr17_-_80062199 0.03 ENSMUST00000184635.1
heterogeneous nuclear ribonucleoprotein L-like
chrX_-_23285532 0.03 ENSMUST00000115319.2
kelch-like 13
chr6_+_113442569 0.02 ENSMUST00000101070.4
jagunal homolog 1 (Drosophila)
chr2_+_32395896 0.02 ENSMUST00000028162.3
prostaglandin E synthase 2
chr17_-_30576241 0.02 ENSMUST00000079924.5
ENSMUST00000168787.1
BTB (POZ) domain containing 9
chr12_-_105685235 0.02 ENSMUST00000041055.7
autophagy related 2B
chr11_+_3290300 0.02 ENSMUST00000057089.6
ENSMUST00000093402.5
POZ (BTB) and AT hook containing zinc finger 1
chr9_-_106199253 0.02 ENSMUST00000140761.1
protein phosphatase 1M
chr11_+_30771726 0.01 ENSMUST00000041231.7
proteasome (prosome, macropain) activator subunit 4
chr5_-_21424664 0.01 ENSMUST00000115245.1
ENSMUST00000030552.5
coiled-coil domain containing 146
chr11_+_97663366 0.01 ENSMUST00000044730.5
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 6
chr11_-_120348475 0.01 ENSMUST00000062147.7
ENSMUST00000128055.1
actin, gamma, cytoplasmic 1
chr19_+_36834215 0.00 ENSMUST00000025729.5
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase 2
chr11_-_100738153 0.00 ENSMUST00000155500.1
ENSMUST00000107364.1
ENSMUST00000019317.5
RAB5C, member RAS oncogene family
chr17_+_25773769 0.00 ENSMUST00000134108.1
ENSMUST00000002350.4
nuclear prelamin A recognition factor-like
chr11_-_116131073 0.00 ENSMUST00000106440.2
ENSMUST00000067632.3
tripartite motif-containing 65

Network of associatons between targets according to the STRING database.

First level regulatory network of Foxn1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:2001106 regulation of Rho guanyl-nucleotide exchange factor activity(GO:2001106)
0.1 0.5 GO:1990839 response to endothelin(GO:1990839)
0.1 0.9 GO:1904668 mitotic spindle midzone assembly(GO:0051256) positive regulation of ubiquitin protein ligase activity(GO:1904668)
0.1 0.2 GO:0040030 regulation of molecular function, epigenetic(GO:0040030)
0.1 0.2 GO:0097051 establishment of protein localization to endoplasmic reticulum membrane(GO:0097051)
0.1 0.2 GO:0035964 COPI-coated vesicle budding(GO:0035964) protein localization to endoplasmic reticulum exit site(GO:0070973)
0.1 0.3 GO:0010796 regulation of multivesicular body size(GO:0010796)
0.1 0.2 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.1 0.3 GO:0009597 detection of virus(GO:0009597)
0.1 0.2 GO:0086047 membrane depolarization during Purkinje myocyte cell action potential(GO:0086047)
0.0 0.2 GO:0036215 response to stem cell factor(GO:0036215) cellular response to stem cell factor stimulus(GO:0036216) Kit signaling pathway(GO:0038109)
0.0 0.2 GO:0001827 inner cell mass cell fate commitment(GO:0001827)
0.0 0.2 GO:0035106 operant conditioning(GO:0035106)
0.0 0.1 GO:1900275 negative regulation of phospholipase C activity(GO:1900275)
0.0 0.3 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.2 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0 0.2 GO:0002084 protein depalmitoylation(GO:0002084) positive regulation of pinocytosis(GO:0048549) macromolecule depalmitoylation(GO:0098734)
0.0 0.2 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.0 0.2 GO:1900034 regulation of cellular response to heat(GO:1900034)
0.0 0.1 GO:1903348 positive regulation of bicellular tight junction assembly(GO:1903348)
0.0 0.3 GO:0051292 nuclear pore complex assembly(GO:0051292)
0.0 0.1 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 0.1 GO:1905077 negative regulation of interleukin-17 secretion(GO:1905077)
0.0 0.1 GO:2001166 regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168)
0.0 0.3 GO:0046498 S-adenosylhomocysteine metabolic process(GO:0046498)
0.0 0.2 GO:0061635 regulation of protein complex stability(GO:0061635)
0.0 0.2 GO:0002903 negative regulation of B cell apoptotic process(GO:0002903)
0.0 0.2 GO:0032119 sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
0.0 0.1 GO:0002317 plasma cell differentiation(GO:0002317)
0.0 0.5 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.0 0.0 GO:0032253 dense core granule localization(GO:0032253) regulation of vesicle transport along microtubule(GO:1901608) dense core granule transport(GO:1901950) regulation of dense core granule transport(GO:1904809) positive regulation of dense core granule transport(GO:1904811)
0.0 0.2 GO:1902170 cellular response to reactive nitrogen species(GO:1902170)
0.0 0.1 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.0 0.1 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.0 0.1 GO:0035166 post-embryonic hemopoiesis(GO:0035166)
0.0 0.4 GO:0042753 positive regulation of circadian rhythm(GO:0042753)
0.0 0.1 GO:2000628 regulation of miRNA metabolic process(GO:2000628)
0.0 0.1 GO:1903748 negative regulation of establishment of protein localization to mitochondrion(GO:1903748)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0044753 amphisome(GO:0044753)
0.0 0.3 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.3 GO:0008091 spectrin(GO:0008091)
0.0 0.2 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.0 0.3 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.0 0.1 GO:0032437 cuticular plate(GO:0032437)
0.0 0.1 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 0.1 GO:0033503 HULC complex(GO:0033503)
0.0 0.1 GO:0033648 host intracellular organelle(GO:0033647) host intracellular membrane-bounded organelle(GO:0033648)
0.0 0.4 GO:0097546 ciliary base(GO:0097546)
0.0 0.2 GO:0000159 protein phosphatase type 2A complex(GO:0000159)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0048408 epidermal growth factor binding(GO:0048408)
0.1 0.2 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.1 0.3 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.1 0.3 GO:1904288 BAT3 complex binding(GO:1904288)
0.1 0.2 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.1 0.2 GO:0001888 glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0001888)
0.0 0.3 GO:0097322 7SK snRNA binding(GO:0097322)
0.0 0.1 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.0 0.1 GO:0051538 3 iron, 4 sulfur cluster binding(GO:0051538)
0.0 0.2 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.0 0.3 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.1 GO:0004335 galactokinase activity(GO:0004335)
0.0 0.9 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.2 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.0 GO:0001003 polymerase III regulatory region sequence-specific DNA binding(GO:0000992) RNA polymerase III type 1 promoter sequence-specific DNA binding(GO:0001002) RNA polymerase III type 2 promoter sequence-specific DNA binding(GO:0001003) RNA polymerase III transcription factor activity, sequence-specific DNA binding(GO:0001034)
0.0 0.1 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.0 0.3 GO:0031489 myosin V binding(GO:0031489)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 0.9 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.3 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.4 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.2 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.2 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.0 0.4 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins