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2D miR_HR1_12

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Results for Trp73

Z-value: 0.19

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Transcription factors associated with Trp73

Gene Symbol Gene ID Gene Info
ENSMUSG00000029026.10 transformation related protein 73

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Trp73mm10_v2_chr4_-_154097105_154097173-0.421.7e-01Click!

Activity profile of Trp73 motif

Sorted Z-values of Trp73 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr15_+_99055164 0.22 ENSMUST00000047104.7
ENSMUST00000024249.3
peripherin
chr5_+_137288273 0.17 ENSMUST00000024099.4
ENSMUST00000085934.3
acetylcholinesterase
chr9_-_58158498 0.17 ENSMUST00000168864.2
immunoglobulin superfamily containing leucine-rich repeat
chr8_+_122269569 0.14 ENSMUST00000055537.2
predicted gene 22
chr2_-_164857671 0.14 ENSMUST00000059954.7
phospholipid transfer protein
chr3_-_89402650 0.13 ENSMUST00000168325.1
ENSMUST00000057431.5
lens epithelial protein
chr2_-_164857542 0.12 ENSMUST00000109316.1
ENSMUST00000156255.1
ENSMUST00000128110.1
ENSMUST00000109317.3
phospholipid transfer protein
chr15_+_84232030 0.11 ENSMUST00000023072.6
parvin, beta
chr15_-_7398334 0.11 ENSMUST00000096494.4
EGF-like, fibronectin type III and laminin G domains
chr7_-_31054815 0.11 ENSMUST00000071697.4
ENSMUST00000108110.3
FXYD domain-containing ion transport regulator 1
chr15_-_7398233 0.10 ENSMUST00000058593.3
EGF-like, fibronectin type III and laminin G domains
chr4_-_106804998 0.10 ENSMUST00000065253.6
acyl-CoA thioesterase 11
chr5_-_139819906 0.09 ENSMUST00000147328.1
transmembrane protein 184a
chr9_-_58313189 0.09 ENSMUST00000061799.8
lysyl oxidase-like 1
chr2_-_127541385 0.08 ENSMUST00000103214.2
prominin 2
chr3_-_89245829 0.08 ENSMUST00000041022.8
tripartite motif-containing 46
chr2_-_127541412 0.08 ENSMUST00000028855.7
prominin 2
chr4_-_49451134 0.07 ENSMUST00000107697.1
ENSMUST00000095086.2
acyl-coenzyme A amino acid N-acyltransferase 1
chr2_+_119237531 0.07 ENSMUST00000110817.2
serine protease inhibitor, Kunitz type 1
chr1_-_5070281 0.07 ENSMUST00000147158.1
ENSMUST00000118000.1
regulator of G-protein signaling 20
chr11_-_103344651 0.07 ENSMUST00000041385.7
Rho GTPase activating protein 27
chr18_+_51117754 0.07 ENSMUST00000116639.2
proline rich 16
chr11_+_114851507 0.06 ENSMUST00000177952.1
G protein-coupled receptor, family C, group 5, member C
chr9_+_108986163 0.06 ENSMUST00000052724.3
urocortin 2
chr10_-_62651194 0.06 ENSMUST00000020270.4
DEAD (Asp-Glu-Ala-Asp) box polypeptide 50
chr2_+_119237351 0.06 ENSMUST00000028783.7
serine protease inhibitor, Kunitz type 1
chr12_-_84876479 0.06 ENSMUST00000163189.1
ENSMUST00000110254.2
ENSMUST00000002073.6
latent transforming growth factor beta binding protein 2
chr3_-_89245159 0.06 ENSMUST00000090924.6
tripartite motif-containing 46
chr2_+_119237453 0.06 ENSMUST00000110816.1
serine protease inhibitor, Kunitz type 1
chr12_+_109747903 0.06 ENSMUST00000183084.1
ENSMUST00000182300.1
miRNA containing gene
chr4_+_119232896 0.05 ENSMUST00000121111.2
ENSMUST00000030393.6
ENSMUST00000102662.4
leprecan 1
chr11_-_69948145 0.05 ENSMUST00000179298.1
ENSMUST00000018710.6
ENSMUST00000135437.1
ENSMUST00000141837.2
ENSMUST00000142500.1
solute carrier family 2 (facilitated glucose transporter), member 4
chr9_-_64341145 0.05 ENSMUST00000120760.1
ENSMUST00000168844.2
DIS3 mitotic control homolog (S. cerevisiae)-like
chr11_-_33578933 0.05 ENSMUST00000020366.1
ENSMUST00000135350.1
gamma-aminobutyric acid (GABA) A receptor, pi
chr19_-_34747289 0.05 ENSMUST00000009522.3
solute carrier family 16 (monocarboxylic acid transporters), member 12
chr5_-_30960326 0.04 ENSMUST00000074840.5
prolactin regulatory element binding
chr1_+_135729147 0.04 ENSMUST00000027677.7
cysteine and glycine-rich protein 1
chr17_+_28232723 0.04 ENSMUST00000002320.8
peroxisome proliferator activator receptor delta
chr1_+_55088132 0.04 ENSMUST00000075242.6
heat shock protein 1 (chaperonin 10)
chr5_-_30960236 0.04 ENSMUST00000088063.2
prolactin regulatory element binding
chr14_+_34086008 0.04 ENSMUST00000120077.1
annexin A8
chr7_-_5014645 0.04 ENSMUST00000165320.1
Flt3 interacting zinc finger protein 1
chr3_+_159839729 0.04 ENSMUST00000068952.5
wntless homolog (Drosophila)
chr19_-_4943049 0.03 ENSMUST00000133254.1
ENSMUST00000120475.1
ENSMUST00000025834.7
pellino 3
chr1_+_153665274 0.03 ENSMUST00000152114.1
ENSMUST00000111812.1
regulator of G-protein signaling 8
chr7_-_140882274 0.03 ENSMUST00000026559.7
sirtuin 3
chr13_-_55021287 0.03 ENSMUST00000148221.1
ENSMUST00000052949.6
hexokinase 3
chr5_-_36748639 0.03 ENSMUST00000071949.3
biogenesis of organelles complex-1, subunit 4, cappuccino
chr9_-_67760208 0.03 ENSMUST00000068526.5
RIKEN cDNA M5C1000I18 gene
chr11_+_57801575 0.03 ENSMUST00000020826.5
SAP30-like
chr16_-_18629864 0.03 ENSMUST00000096987.5
septin 5
chr13_-_55021196 0.03 ENSMUST00000153665.1
hexokinase 3
chr19_+_46304709 0.03 ENSMUST00000073116.5
nuclear factor of kappa light polypeptide gene enhancer in B cells 2, p49/p100
chr12_+_84875769 0.03 ENSMUST00000171853.1
RIKEN cDNA D030025P21 gene
chr14_-_24245913 0.03 ENSMUST00000073687.6
ENSMUST00000090398.4
discs, large homolog 5 (Drosophila)
chr11_+_60931998 0.03 ENSMUST00000019076.3
mitogen-activated protein kinase kinase 3
chr11_+_114851142 0.03 ENSMUST00000133245.1
ENSMUST00000122967.2
G protein-coupled receptor, family C, group 5, member C
chr3_+_89245952 0.03 ENSMUST00000040888.5
keratinocyte associated protein 2
chr5_-_92083455 0.03 ENSMUST00000169094.1
ENSMUST00000167918.1
GTPase activating protein (SH3 domain) binding protein 2
chr14_+_34085978 0.03 ENSMUST00000022519.8
annexin A8
chr19_-_47157764 0.03 ENSMUST00000178630.1
calcium homeostasis modulator 3
chr8_+_84125989 0.02 ENSMUST00000093380.4
podocan-like 1
chr11_+_69913888 0.02 ENSMUST00000072581.2
ENSMUST00000116358.1
G protein pathway suppressor 2
chr4_+_109000606 0.02 ENSMUST00000065977.4
ENSMUST00000102736.2
nardilysin, N-arginine dibasic convertase, NRD convertase 1
chr11_-_120348513 0.02 ENSMUST00000071555.6
actin, gamma, cytoplasmic 1
chr10_-_57532489 0.02 ENSMUST00000020027.4
serine incorporator 1
chr8_+_27085520 0.02 ENSMUST00000178514.1
ENSMUST00000033876.7
G protein-coupled receptor 124
chr15_+_30172570 0.02 ENSMUST00000081728.5
catenin (cadherin associated protein), delta 2
chr11_-_100738153 0.02 ENSMUST00000155500.1
ENSMUST00000107364.1
ENSMUST00000019317.5
RAB5C, member RAS oncogene family
chr2_+_34772089 0.02 ENSMUST00000028222.6
ENSMUST00000100171.2
heat shock protein 5
chr10_-_127311740 0.02 ENSMUST00000037290.5
ENSMUST00000171564.1
methionine-tRNA synthetase
chr10_+_127642975 0.02 ENSMUST00000092074.5
ENSMUST00000120279.1
signal transducer and activator of transcription 6
chr11_+_46404720 0.02 ENSMUST00000063166.5
family with sequence similarity 71, member B
chr11_-_95699143 0.01 ENSMUST00000062249.2
predicted gene 9796
chr10_+_105841064 0.01 ENSMUST00000020049.8
coiled-coil domain containing 59
chr13_+_48261427 0.01 ENSMUST00000021810.1
inhibitor of DNA binding 4
chr10_+_52391606 0.01 ENSMUST00000067085.4
nephrocan
chr5_-_92083667 0.01 ENSMUST00000113127.3
GTPase activating protein (SH3 domain) binding protein 2
chr8_-_70659645 0.01 ENSMUST00000070173.7
pyroglutamyl-peptidase I
chr7_+_140881898 0.01 ENSMUST00000026560.7
proteasome (prosome, macropain) 26S subunit, non-ATPase, 13
chr12_-_45074112 0.01 ENSMUST00000120531.1
ENSMUST00000143376.1
syntaxin binding protein 6 (amisyn)
chr8_+_27085835 0.01 ENSMUST00000165366.2
G protein-coupled receptor 124
chr18_+_56432116 0.01 ENSMUST00000070166.5
GRAM domain containing 3
chr4_-_11386757 0.01 ENSMUST00000108313.1
ENSMUST00000108311.2
epithelial splicing regulatory protein 1
chr6_+_83054653 0.01 ENSMUST00000092618.6
ancient ubiquitous protein 1
chr19_-_7483241 0.01 ENSMUST00000025667.6
ENSMUST00000065304.5
ENSMUST00000088171.4
reticulon 3
chr11_-_20831009 0.01 ENSMUST00000047028.8
lectin, galactoside binding-like
chr18_-_32036941 0.01 ENSMUST00000134663.1
myosin VIIB
chr4_-_11386679 0.01 ENSMUST00000043781.7
ENSMUST00000108310.1
epithelial splicing regulatory protein 1
chr4_-_49383576 0.00 ENSMUST00000107698.1
acyl-coenzyme A amino acid N-acyltransferase 2
chr7_-_116038734 0.00 ENSMUST00000166877.1
SRY-box containing gene 6
chr5_+_43233928 0.00 ENSMUST00000114066.1
ENSMUST00000114065.1
cytoplasmic polyadenylation element binding protein 2
chrX_-_60147643 0.00 ENSMUST00000033478.4
ENSMUST00000101531.3
mcf.2 transforming sequence
chr2_-_90904827 0.00 ENSMUST00000005647.3
NADH dehydrogenase (ubiquinone) Fe-S protein 3
chr19_-_7105729 0.00 ENSMUST00000113383.2
fibronectin leucine rich transmembrane protein 1
chr2_-_170497141 0.00 ENSMUST00000038824.5
cytochrome P450, family 24, subfamily a, polypeptide 1
chr1_-_39478734 0.00 ENSMUST00000054462.5
TBC1 domain family, member 8
chr4_-_45489794 0.00 ENSMUST00000146236.1
src homology 2 domain-containing transforming protein B

Network of associatons between targets according to the STRING database.

First level regulatory network of Trp73

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0042360 vitamin E metabolic process(GO:0042360)
0.0 0.2 GO:2001287 negative regulation of caveolin-mediated endocytosis(GO:2001287)
0.0 0.1 GO:0071963 establishment or maintenance of cell polarity regulating cell shape(GO:0071963)
0.0 0.2 GO:1900619 acetylcholine metabolic process(GO:0008291) acetate ester metabolic process(GO:1900619)
0.0 0.1 GO:0048209 regulation of vesicle targeting, to, from or within Golgi(GO:0048209)
0.0 0.1 GO:0033685 negative regulation of luteinizing hormone secretion(GO:0033685)
0.0 0.2 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.1 GO:1903797 positive regulation of sodium ion export(GO:1903275) positive regulation of sodium ion export from cell(GO:1903278) positive regulation of inorganic anion transmembrane transport(GO:1903797)
0.0 0.0 GO:0015881 creatine transport(GO:0015881)
0.0 0.1 GO:0018992 germ-line sex determination(GO:0018992)
0.0 0.0 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0044299 C-fiber(GO:0044299)
0.0 0.2 GO:0044393 microspike(GO:0044393)
0.0 0.1 GO:1990769 proximal neuron projection(GO:1990769)
0.0 0.2 GO:0043083 synaptic cleft(GO:0043083)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0004104 cholinesterase activity(GO:0004104)
0.0 0.1 GO:0005118 sevenless binding(GO:0005118)
0.0 0.0 GO:0005308 creatine transmembrane transporter activity(GO:0005308)
0.0 0.0 GO:0016501 prostacyclin receptor activity(GO:0016501)
0.0 0.1 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport