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2D miR_HR1_12

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Results for Hes1

Z-value: 0.88

Motif logo

Transcription factors associated with Hes1

Gene Symbol Gene ID Gene Info
ENSMUSG00000022528.7 hes family bHLH transcription factor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Hes1mm10_v2_chr16_+_30065333_300653510.175.9e-01Click!

Activity profile of Hes1 motif

Sorted Z-values of Hes1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr11_+_61022560 1.92 ENSMUST00000089184.4
potassium inwardly-rectifying channel, subfamily J, member 12
chr5_+_141241490 1.68 ENSMUST00000085774.4
sidekick homolog 1 (chicken)
chr12_-_17176888 1.63 ENSMUST00000170580.1
potassium voltage-gated channel, subfamily F, member 1
chr4_+_137277489 1.35 ENSMUST00000045747.4
wingless-related MMTV integration site 4
chr9_+_46012810 1.15 ENSMUST00000126865.1
SIK family kinase 3
chr1_+_36511867 1.12 ENSMUST00000001166.7
ENSMUST00000097776.3
cyclin M3
chr2_+_157914618 1.08 ENSMUST00000109523.1
V-set and transmembrane domain containing 2-like
chr2_+_180725263 1.03 ENSMUST00000094218.3
solute carrier family 17, member 9
chr14_-_79301623 0.99 ENSMUST00000022595.7
regulator of cell cycle
chr7_-_19796789 0.98 ENSMUST00000108449.2
ENSMUST00000043822.7
Casitas B-lineage lymphoma c
chr11_+_98348404 0.95 ENSMUST00000078694.6
protein phosphatase 1, regulatory (inhibitor) subunit 1B
chr7_-_101864093 0.93 ENSMUST00000106981.1
folate receptor 1 (adult)
chr4_-_53262547 0.90 ENSMUST00000098075.2
expressed sequence AI427809
chr11_+_95010277 0.87 ENSMUST00000124735.1
sterile alpha motif domain containing 14
chr5_-_138996087 0.86 ENSMUST00000110897.1
platelet derived growth factor, alpha
chr17_-_26199008 0.84 ENSMUST00000142410.1
ENSMUST00000120333.1
ENSMUST00000039113.7
protein disulfide isomerase associated 2
chr11_+_113619318 0.84 ENSMUST00000146390.2
ENSMUST00000106630.1
somatostatin receptor 2
chr2_+_155381808 0.83 ENSMUST00000043237.7
ENSMUST00000174685.1
transformation related protein 53 inducible nuclear protein 2
chr5_+_113735782 0.81 ENSMUST00000065698.5
FIC domain containing
chr1_-_84696182 0.81 ENSMUST00000049126.6
delta/notch-like EGF-related receptor
chr11_-_12026237 0.80 ENSMUST00000150972.1
growth factor receptor bound protein 10
chr11_+_114765363 0.77 ENSMUST00000138804.1
ENSMUST00000084368.5
kinesin family member 19A
chr9_+_35211155 0.77 ENSMUST00000034541.5
signal recognition particle receptor ('docking protein')
chr6_-_90716489 0.68 ENSMUST00000101153.3
IQ motif and Sec7 domain 1
chr17_-_87282771 0.66 ENSMUST00000161759.1
RIKEN cDNA 4833418N02 gene
chr16_+_97356721 0.66 ENSMUST00000047275.6
beta-site APP-cleaving enzyme 2
chr5_+_104459450 0.64 ENSMUST00000086831.3
polycystic kidney disease 2
chr11_+_53457184 0.64 ENSMUST00000109013.2
shroom family member 1
chr7_+_99535652 0.63 ENSMUST00000032995.8
ENSMUST00000162404.1
arrestin, beta 1
chr19_-_5845471 0.62 ENSMUST00000174287.1
ENSMUST00000173672.1
nuclear paraspeckle assembly transcript 1 (non-protein coding)
chr5_-_93045022 0.61 ENSMUST00000061328.5
sosondowah ankyrin repeat domain family member B
chr11_-_116086929 0.61 ENSMUST00000074628.6
ENSMUST00000106444.3
WW domain binding protein 2
chr1_+_120340569 0.61 ENSMUST00000037286.8
complement component 1, q subcomponent-like 2
chr13_-_56296551 0.60 ENSMUST00000021970.9
chemokine (C-X-C motif) ligand 14
chr14_-_51146757 0.60 ENSMUST00000080126.2
ribonuclease, RNase A family, 1 (pancreatic)
chr4_+_43562672 0.59 ENSMUST00000167751.1
ENSMUST00000132631.1
cAMP responsive element binding protein 3
chr4_+_41762309 0.56 ENSMUST00000108042.2
interleukin 11 receptor, alpha chain 1
chr17_-_87282793 0.55 ENSMUST00000146560.2
RIKEN cDNA 4833418N02 gene
chr2_+_156840966 0.55 ENSMUST00000109564.1
TGFB-induced factor homeobox 2
chr11_-_12026732 0.55 ENSMUST00000143915.1
growth factor receptor bound protein 10
chr2_-_172043466 0.54 ENSMUST00000087950.3
cerebellin 4 precursor protein
chr12_-_50649190 0.54 ENSMUST00000002765.7
protein kinase D1
chr11_+_69095217 0.54 ENSMUST00000101004.2
period circadian clock 1
chr14_-_60177482 0.53 ENSMUST00000140924.1
ATPase, aminophospholipid transporter-like, class I, type 8A, member 2
chr7_-_29906087 0.53 ENSMUST00000053521.8
zinc finger protein 27
chr10_-_30842765 0.52 ENSMUST00000019924.8
hairy/enhancer-of-split related with YRPW motif 2
chr19_-_8723356 0.51 ENSMUST00000170157.1
solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2
chr1_+_95313607 0.51 ENSMUST00000059975.6
family with sequence similarity 174, member A
chr7_+_28766747 0.51 ENSMUST00000170068.1
ENSMUST00000072965.4
sirtuin 2
chr13_-_48625571 0.50 ENSMUST00000035824.9
protein tyrosine phosphatase domain containing 1
chr10_+_11343387 0.49 ENSMUST00000069106.4
epilepsy, progressive myoclonic epilepsy, type 2 gene alpha
chr6_-_65144908 0.49 ENSMUST00000031982.4
hematopoietic prostaglandin D synthase
chr12_+_116077720 0.48 ENSMUST00000011315.3
vasoactive intestinal peptide receptor 2
chr5_+_107437908 0.48 ENSMUST00000094541.2
BTB (POZ) domain containing 8
chr2_-_52742142 0.48 ENSMUST00000138290.1
signal transducing adaptor molecule (SH3 domain and ITAM motif) 2
chr9_-_108305941 0.47 ENSMUST00000044725.7
T cell leukemia translocation altered gene
chr18_+_65800543 0.47 ENSMUST00000025394.6
ENSMUST00000153193.1
SEC11 homolog C (S. cerevisiae)
chr8_-_70353243 0.47 ENSMUST00000075666.6
UPF1 regulator of nonsense transcripts homolog (yeast)
chr7_+_99535439 0.47 ENSMUST00000098266.2
ENSMUST00000179755.1
arrestin, beta 1
chr7_+_35119285 0.46 ENSMUST00000042985.9
CCAAT/enhancer binding protein (C/EBP), alpha
chr11_+_53457209 0.45 ENSMUST00000018531.5
shroom family member 1
chr11_+_100860447 0.45 ENSMUST00000107357.2
signal transducer and activator of transcription 5A
chr2_-_52742169 0.43 ENSMUST00000102759.1
ENSMUST00000127316.1
signal transducing adaptor molecule (SH3 domain and ITAM motif) 2
chr4_-_58553311 0.43 ENSMUST00000107571.1
ENSMUST00000055018.4
lysophosphatidic acid receptor 1
chrX_-_106221145 0.42 ENSMUST00000113495.2
TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr2_+_28205648 0.42 ENSMUST00000102879.3
ENSMUST00000028177.4
olfactomedin 1
chr2_-_168741752 0.42 ENSMUST00000029060.4
ATPase, class II, type 9A
chrX_+_20688379 0.42 ENSMUST00000033380.6
cyclin-dependent kinase 16
chr4_-_58553184 0.41 ENSMUST00000145361.1
lysophosphatidic acid receptor 1
chr14_-_29721835 0.41 ENSMUST00000022567.7
calcium channel, voltage-dependent, alpha2/delta subunit 3
chr9_+_75410145 0.41 ENSMUST00000180533.1
ENSMUST00000180574.1
RIKEN cDNA 4933433G15 gene
chr3_-_108086590 0.40 ENSMUST00000102638.1
ENSMUST00000102637.1
adenosine monophosphate deaminase 2
chr18_-_15403680 0.40 ENSMUST00000079081.6
aquaporin 4
chr16_+_30008657 0.40 ENSMUST00000181485.1
RIKEN cDNA 4632428C04 gene
chr7_+_19083842 0.40 ENSMUST00000032568.7
ENSMUST00000122999.1
ENSMUST00000108473.3
ENSMUST00000108474.1
dystrophia myotonica-protein kinase
chr1_-_156035891 0.40 ENSMUST00000126448.1
torsin A interacting protein 1
chr4_-_58553553 0.39 ENSMUST00000107575.2
ENSMUST00000107574.1
ENSMUST00000147354.1
lysophosphatidic acid receptor 1
chr16_-_97922582 0.39 ENSMUST00000170757.1
C2 calcium-dependent domain containing 2
chr2_+_69789647 0.39 ENSMUST00000112266.1
phosphatase, orphan 2
chr2_+_69789621 0.39 ENSMUST00000151298.1
ENSMUST00000028494.2
phosphatase, orphan 2
chr4_-_123904826 0.39 ENSMUST00000181292.1
predicted gene, 26606
chr5_+_143403819 0.39 ENSMUST00000110731.2
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2
chr15_+_89322969 0.38 ENSMUST00000066991.5
adrenomedullin 2
chr5_+_34369909 0.38 ENSMUST00000180376.1
family with sequence similarity 193, member A
chr9_+_46012822 0.38 ENSMUST00000120463.2
ENSMUST00000120247.1
SIK family kinase 3
chr8_-_105938384 0.38 ENSMUST00000034369.8
proteasome (prosome, macropain) subunit, beta type 10
chr4_-_45012287 0.38 ENSMUST00000055028.8
ENSMUST00000180217.1
ENSMUST00000107817.2
zinc finger and BTB domain containing 5
chr6_-_70792155 0.38 ENSMUST00000066134.5
ribose 5-phosphate isomerase A
chr1_-_156036473 0.38 ENSMUST00000097527.3
ENSMUST00000027738.7
torsin A interacting protein 1
chr2_-_69789568 0.37 ENSMUST00000094942.3
coiled-coil domain containing 173
chr11_-_116828000 0.37 ENSMUST00000047715.5
ENSMUST00000021170.2
matrix-remodelling associated 7
chr7_-_45459839 0.36 ENSMUST00000094434.4
ferritin light chain 1
chr12_-_3357012 0.36 ENSMUST00000180719.1
predicted gene, 26520
chr8_-_111743799 0.36 ENSMUST00000166232.2
breast cancer anti-estrogen resistance 1
chr11_-_89302545 0.35 ENSMUST00000061728.3
noggin
chr18_+_75820174 0.35 ENSMUST00000058997.7
zinc finger and BTB domain containing 7C
chr10_+_77606571 0.34 ENSMUST00000099538.5
SMT3 suppressor of mif two 3 homolog 3 (yeast)
chr14_+_65266701 0.33 ENSMUST00000169656.1
F-box protein 16
chr8_-_107096510 0.33 ENSMUST00000068388.8
ENSMUST00000133925.1
ENSMUST00000068421.6
ENSMUST00000116425.2
telomeric repeat binding factor 2
chr6_+_17636983 0.32 ENSMUST00000015877.7
capping protein (actin filament) muscle Z-line, alpha 2
chr7_+_19004047 0.32 ENSMUST00000053713.3
interferon regulatory factor 2 binding protein 1
chr14_-_78536854 0.32 ENSMUST00000022593.5
A kinase (PRKA) anchor protein 11
chr3_+_28781305 0.32 ENSMUST00000060500.7
eukaryotic translation initiation factor 5A2
chr19_-_36057340 0.32 ENSMUST00000164639.1
ENSMUST00000166074.1
ENSMUST00000099505.3
5-hydroxytryptamine (serotonin) receptor 7
chr11_+_83746940 0.32 ENSMUST00000070832.2
RIKEN cDNA 1100001G20 gene
chr11_-_66525964 0.31 ENSMUST00000066679.6
shisa homolog 6 (Xenopus laevis)
chr7_-_31115227 0.31 ENSMUST00000168884.1
ENSMUST00000108102.2
hepsin
chr2_+_155382186 0.31 ENSMUST00000134218.1
transformation related protein 53 inducible nuclear protein 2
chr4_-_145246855 0.30 ENSMUST00000030336.4
tumor necrosis factor receptor superfamily, member 1b
chr6_+_86526271 0.30 ENSMUST00000180896.1
RIKEN cDNA 1600020E01 gene
chr7_-_29906524 0.30 ENSMUST00000159920.1
ENSMUST00000162592.1
zinc finger protein 27
chr9_-_75409951 0.30 ENSMUST00000049355.10
mitogen-activated protein kinase 6
chr1_+_93754899 0.30 ENSMUST00000027502.9
autophagy related 4B, cysteine peptidase
chr11_+_120673018 0.30 ENSMUST00000106158.2
ENSMUST00000103016.1
ENSMUST00000168714.1
alveolar soft part sarcoma chromosome region, candidate 1 (human)
chr5_-_36695969 0.30 ENSMUST00000031091.9
ENSMUST00000140063.1
DNA segment, Chr 5, ERATO Doi 579, expressed
chr8_+_106603351 0.30 ENSMUST00000000312.5
ENSMUST00000167688.1
cadherin 1
chr18_-_53418004 0.29 ENSMUST00000025419.7
peptidylprolyl isomerase C
chr10_+_79854618 0.29 ENSMUST00000165704.1
polypyrimidine tract binding protein 1
chrX_-_155338460 0.29 ENSMUST00000026328.4
peroxiredoxin 4
chr7_+_25897620 0.28 ENSMUST00000072438.6
ENSMUST00000005477.5
cytochrome P450, family 2, subfamily b, polypeptide 10
chr5_+_110176640 0.28 ENSMUST00000112512.1
golgi autoantigen, golgin subfamily a, 3
chr10_+_79854658 0.28 ENSMUST00000171599.1
ENSMUST00000095457.4
polypyrimidine tract binding protein 1
chr1_+_119526125 0.28 ENSMUST00000183952.1
Transmembrane protein 185B
chr5_+_118027743 0.28 ENSMUST00000031304.7
tescalcin
chr7_-_93081027 0.28 ENSMUST00000098303.1
predicted gene 9934
chr2_+_162931520 0.28 ENSMUST00000130411.1
serine/arginine-rich splicing factor 6
chr17_+_28232723 0.27 ENSMUST00000002320.8
peroxisome proliferator activator receptor delta
chr19_+_3851972 0.27 ENSMUST00000025760.6
choline kinase alpha
chr7_-_139582790 0.27 ENSMUST00000106095.2
NK6 homeobox 2
chr15_-_95528228 0.27 ENSMUST00000075275.2
NEL-like 2
chr10_-_81545175 0.27 ENSMUST00000043604.5
guanine nucleotide binding protein, alpha 11
chr3_+_157566868 0.27 ENSMUST00000041175.6
ENSMUST00000173533.1
prostaglandin E receptor 3 (subtype EP3)
chr19_+_10018193 0.27 ENSMUST00000113161.2
ENSMUST00000117641.1
RAB3A interacting protein (rabin3)-like 1
chr1_-_106796609 0.27 ENSMUST00000112736.1
vacuolar protein sorting 4b (yeast)
chr17_-_26090251 0.27 ENSMUST00000040907.6
2-4-dienoyl-Coenzyme A reductase 2, peroxisomal
chr4_-_45012093 0.27 ENSMUST00000131991.1
zinc finger and BTB domain containing 5
chr2_+_103970221 0.26 ENSMUST00000111140.2
ENSMUST00000111139.2
LIM domain only 2
chr14_-_30626196 0.26 ENSMUST00000112210.3
ENSMUST00000112211.2
ENSMUST00000112208.1
protein kinase C, delta
chr2_-_38712195 0.26 ENSMUST00000112883.1
nuclear receptor subfamily 5, group A, member 1
chr3_-_88177671 0.26 ENSMUST00000181837.1
RIKEN cDNA 1700113A16 gene
chr11_+_77462325 0.26 ENSMUST00000102493.1
coronin 6
chr11_+_99041237 0.26 ENSMUST00000017637.6
insulin-like growth factor binding protein 4
chr8_+_75033673 0.26 ENSMUST00000078847.5
ENSMUST00000165630.1
target of myb1 homolog (chicken)
chr14_-_70443219 0.25 ENSMUST00000180358.1
polymerase (RNA) III (DNA directed) polypeptide D
chr4_+_126753770 0.25 ENSMUST00000102607.3
ENSMUST00000047431.4
ENSMUST00000132660.1
expressed sequence AU040320
chr18_-_80713062 0.25 ENSMUST00000170905.1
ENSMUST00000078049.4
nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1
chr8_-_22060305 0.25 ENSMUST00000006742.4
ATPase, Cu++ transporting, beta polypeptide
chr11_-_108343917 0.25 ENSMUST00000059595.4
protein kinase C, alpha
chr15_+_76331288 0.25 ENSMUST00000172281.1
GPI anchor attachment protein 1
chr5_-_108629712 0.25 ENSMUST00000046603.8
cyclin G associated kinase
chr13_-_68999518 0.24 ENSMUST00000022013.7
adenylate cyclase 2
chr11_+_116531744 0.24 ENSMUST00000106387.2
ENSMUST00000100201.3
sphingosine kinase 1
chr1_+_33908172 0.24 ENSMUST00000182513.1
ENSMUST00000183034.1
dystonin
chr11_+_121434913 0.24 ENSMUST00000026175.2
ENSMUST00000092302.4
ENSMUST00000103014.3
fructosamine 3 kinase
chr9_-_87255536 0.24 ENSMUST00000093802.4
RIKEN cDNA 4922501C03 gene
chr11_+_100545607 0.24 ENSMUST00000092684.5
ENSMUST00000006976.7
tetratricopeptide repeat domain 25
chr9_+_118040509 0.24 ENSMUST00000133580.1
5-azacytidine induced gene 2
chr19_-_24555819 0.23 ENSMUST00000112673.2
ENSMUST00000025800.8
phosphatidylinositol-4-phosphate 5-kinase, type 1 beta
chr14_-_78536762 0.23 ENSMUST00000123853.1
A kinase (PRKA) anchor protein 11
chr6_-_88518760 0.23 ENSMUST00000032168.5
Sec61 alpha 1 subunit (S. cerevisiae)
chr4_-_120747248 0.23 ENSMUST00000030376.7
potassium voltage-gated channel, subfamily Q, member 4
chr13_+_81711407 0.23 ENSMUST00000057598.5
metallo-beta-lactamase domain containing 2
chr11_-_11462408 0.23 ENSMUST00000020413.3
zona pellucida binding protein
chr16_-_20425881 0.22 ENSMUST00000077867.3
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
chr11_+_120608469 0.22 ENSMUST00000106194.1
ENSMUST00000106195.2
neuropeptide B
chr11_-_106788845 0.22 ENSMUST00000123339.1
DEAD (Asp-Glu-Ala-Asp) box polypeptide 5
chr1_-_75210732 0.22 ENSMUST00000113623.1
galactosidase, beta 1-like
chr13_+_37826904 0.22 ENSMUST00000149745.1
ras responsive element binding protein 1
chr2_+_158028481 0.22 ENSMUST00000103123.3
regulation of nuclear pre-mRNA domain containing 1B
chr1_-_93478785 0.22 ENSMUST00000170883.1
high density lipoprotein (HDL) binding protein
chr2_-_90580578 0.22 ENSMUST00000168621.2
protein tyrosine phosphatase, receptor type, J
chr8_-_36249292 0.21 ENSMUST00000065297.5
LON peptidase N-terminal domain and ring finger 1
chr1_-_74951651 0.21 ENSMUST00000164097.1
Indian hedgehog
chr12_-_87200200 0.21 ENSMUST00000037418.5
transmembrane emp24 domain containing 8
chr2_+_158028687 0.21 ENSMUST00000109518.1
ENSMUST00000029180.7
regulation of nuclear pre-mRNA domain containing 1B
chr4_-_135353164 0.20 ENSMUST00000084846.5
ENSMUST00000136342.2
ENSMUST00000105861.1
serine/arginine repetitive matrix 1
chr5_-_31220491 0.20 ENSMUST00000031032.7
protein phosphatase 1G (formerly 2C), magnesium-dependent, gamma isoform
chr6_-_31563978 0.20 ENSMUST00000026698.7
podocalyxin-like
chr10_-_53750880 0.20 ENSMUST00000020003.7
family with sequence similarity 184, member A
chr9_-_35210964 0.20 ENSMUST00000043805.8
ENSMUST00000142595.1
ENSMUST00000127996.1
FAD-dependent oxidoreductase domain containing 1
chr2_+_28641227 0.19 ENSMUST00000028155.5
ENSMUST00000113869.1
ENSMUST00000113867.2
tuberous sclerosis 1
chr2_+_153345809 0.19 ENSMUST00000109790.1
additional sex combs like 1
chr14_-_70443442 0.19 ENSMUST00000000793.5
polymerase (RNA) III (DNA directed) polypeptide D
chr11_-_100759942 0.19 ENSMUST00000107363.2
potassium voltage-gated channel, subfamily H (eag-related), member 4
chr2_+_23069057 0.19 ENSMUST00000114526.1
ENSMUST00000114529.2
acyl-Coenzyme A binding domain containing 5
chr9_-_35558522 0.19 ENSMUST00000034612.5
DEAD (Asp-Glu-Ala-Asp) box polypeptide 25
chr13_-_43480973 0.19 ENSMUST00000144326.2
RAN binding protein 9
chr1_+_191906743 0.19 ENSMUST00000044954.6
solute carrier family 30 (zinc transporter), member 1
chr17_+_57105385 0.19 ENSMUST00000039490.7
tumor necrosis factor (ligand) superfamily, member 9
chr7_+_25077205 0.18 ENSMUST00000179556.1
ENSMUST00000053410.9
zinc finger protein 574
chrX_+_103356464 0.18 ENSMUST00000116547.2
cysteine-rich hydrophobic domain 1
chr3_+_90254163 0.18 ENSMUST00000029545.8
CREB regulated transcription coactivator 2
chr7_+_129257027 0.18 ENSMUST00000094018.4
phosphatidic acid phosphatase type 2 domain containing 1A
chr17_-_56716788 0.18 ENSMUST00000067931.5
vimentin-type intermediate filament associated coiled-coil protein
chr4_+_135728116 0.18 ENSMUST00000102546.3
interleukin 22 receptor, alpha 1
chr2_+_149830840 0.18 ENSMUST00000109934.1
ENSMUST00000140870.1
synapse differentiation inducing 1
chr4_+_115737738 0.18 ENSMUST00000106525.2
EF-hand calcium binding domain 14
chr17_+_44188564 0.18 ENSMUST00000024755.5
chloride intracellular channel 5
chr2_+_105126505 0.18 ENSMUST00000143043.1
Wilms tumor 1 homolog
chr11_-_106789157 0.17 ENSMUST00000129585.1
DEAD (Asp-Glu-Ala-Asp) box polypeptide 5

Network of associatons between targets according to the STRING database.

First level regulatory network of Hes1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0060748 tertiary branching involved in mammary gland duct morphogenesis(GO:0060748) renal vesicle induction(GO:0072034) metanephric mesenchymal cell differentiation(GO:0072162) negative regulation of male gonad development(GO:2000019)
0.3 1.0 GO:0003331 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.3 1.2 GO:1904566 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.3 0.9 GO:0010512 negative regulation of phosphatidylinositol biosynthetic process(GO:0010512)
0.2 0.9 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.2 0.6 GO:0003127 detection of nodal flow(GO:0003127) detection of endogenous stimulus(GO:0009726)
0.2 0.6 GO:0019043 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990) establishment of viral latency(GO:0019043) release from viral latency(GO:0019046)
0.2 0.5 GO:0046959 habituation(GO:0046959)
0.2 0.8 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.2 0.6 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
0.1 0.9 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.1 0.5 GO:2000820 ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910) negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000820)
0.1 0.5 GO:0061428 positive regulation of oocyte development(GO:0060282) negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428) negative regulation of defense response to bacterium(GO:1900425)
0.1 0.2 GO:0035622 intrahepatic bile duct development(GO:0035622)
0.1 1.3 GO:0045719 negative regulation of glycogen biosynthetic process(GO:0045719)
0.1 0.4 GO:1990859 cellular response to endothelin(GO:1990859)
0.1 0.3 GO:0060300 regulation of cytokine activity(GO:0060300)
0.1 0.4 GO:0060376 positive regulation of mast cell differentiation(GO:0060376)
0.1 0.3 GO:0035801 adrenal cortex development(GO:0035801) adrenal cortex formation(GO:0035802) posterior mesonephric tubule development(GO:0072166) negative regulation of metanephric glomerulus development(GO:0072299) negative regulation of metanephric glomerular mesangial cell proliferation(GO:0072302) regulation of metanephric ureteric bud development(GO:2001074) positive regulation of metanephric ureteric bud development(GO:2001076)
0.1 0.4 GO:0002030 inhibitory G-protein coupled receptor phosphorylation(GO:0002030)
0.1 0.3 GO:0048239 negative regulation of DNA recombination at telomere(GO:0048239) regulation of DNA recombination at telomere(GO:0072695)
0.1 0.5 GO:0097167 circadian regulation of translation(GO:0097167)
0.1 0.3 GO:0051385 response to mineralocorticoid(GO:0051385)
0.1 0.5 GO:0015803 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.1 0.9 GO:0003147 neural crest cell migration involved in heart formation(GO:0003147) anterior neural tube closure(GO:0061713) cellular response to folic acid(GO:0071231)
0.1 0.6 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
0.1 0.4 GO:0014722 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.1 0.2 GO:0090650 response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.1 0.4 GO:0006014 D-ribose metabolic process(GO:0006014)
0.1 0.7 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.1 0.5 GO:0032201 telomere maintenance via semi-conservative replication(GO:0032201)
0.1 0.3 GO:1903722 regulation of centriole elongation(GO:1903722)
0.1 0.8 GO:0071763 nuclear membrane organization(GO:0071763)
0.1 0.3 GO:0044565 dendritic cell proliferation(GO:0044565)
0.1 0.3 GO:0060854 patterning of lymph vessels(GO:0060854)
0.1 0.3 GO:0015680 intracellular copper ion transport(GO:0015680)
0.1 0.4 GO:0070295 renal water transport(GO:0003097) renal water absorption(GO:0070295)
0.1 0.5 GO:0072675 osteoclast fusion(GO:0072675)
0.1 0.3 GO:2000611 basement membrane disassembly(GO:0034769) positive regulation of thyroid hormone generation(GO:2000611)
0.1 0.5 GO:0089700 protein kinase D signaling(GO:0089700)
0.1 0.8 GO:0030432 peristalsis(GO:0030432)
0.1 0.5 GO:0061092 regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
0.1 0.3 GO:0051697 protein delipidation(GO:0051697)
0.1 1.0 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.1 0.6 GO:0035437 maintenance of protein localization in endoplasmic reticulum(GO:0035437)
0.1 0.2 GO:0016539 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908) eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552) camera-type eye photoreceptor cell fate commitment(GO:0060220)
0.1 0.3 GO:0032417 positive regulation of sodium:proton antiporter activity(GO:0032417)
0.1 0.8 GO:0071285 cellular response to lithium ion(GO:0071285)
0.1 1.0 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.1 0.3 GO:2000195 negative regulation of female gonad development(GO:2000195)
0.1 0.3 GO:0010360 negative regulation of anion channel activity(GO:0010360) regulation of dense core granule biogenesis(GO:2000705)
0.1 0.2 GO:0071579 regulation of zinc ion transport(GO:0071579)
0.1 1.7 GO:0048148 behavioral response to cocaine(GO:0048148)
0.1 0.3 GO:0042738 exogenous drug catabolic process(GO:0042738)
0.1 0.2 GO:0032227 negative regulation of synaptic transmission, dopaminergic(GO:0032227)
0.1 0.3 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.1 0.2 GO:0060468 prevention of polyspermy(GO:0060468)
0.1 0.3 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.1 0.2 GO:1902528 regulation of protein linear polyubiquitination(GO:1902528) positive regulation of protein linear polyubiquitination(GO:1902530)
0.1 0.8 GO:0007220 Notch receptor processing(GO:0007220)
0.1 1.9 GO:0010107 potassium ion import(GO:0010107)
0.1 0.3 GO:0060697 glucosylceramide catabolic process(GO:0006680) positive regulation of phospholipid catabolic process(GO:0060697)
0.1 0.4 GO:0032264 IMP salvage(GO:0032264)
0.1 0.2 GO:0043519 myosin II filament organization(GO:0031038) regulation of myosin II filament organization(GO:0043519)
0.0 0.2 GO:0035522 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.0 0.2 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.6 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.0 0.1 GO:1904020 positive regulation of adenosine receptor signaling pathway(GO:0060168) regulation of G-protein coupled receptor internalization(GO:1904020)
0.0 0.3 GO:0043415 positive regulation of skeletal muscle tissue regeneration(GO:0043415)
0.0 0.1 GO:0045415 negative regulation of interleukin-8 biosynthetic process(GO:0045415)
0.0 0.4 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.0 0.7 GO:0007190 activation of adenylate cyclase activity(GO:0007190)
0.0 0.1 GO:0006011 UDP-glucose metabolic process(GO:0006011) glucose 1-phosphate metabolic process(GO:0019255)
0.0 1.6 GO:0060351 cartilage development involved in endochondral bone morphogenesis(GO:0060351)
0.0 0.3 GO:0019695 choline metabolic process(GO:0019695)
0.0 0.3 GO:0021912 regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification(GO:0021912)
0.0 0.4 GO:0023041 neuronal signal transduction(GO:0023041)
0.0 0.4 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.0 0.1 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.0 0.1 GO:0046271 coumarin metabolic process(GO:0009804) phenylpropanoid catabolic process(GO:0046271)
0.0 0.2 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.0 0.3 GO:1903025 regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025)
0.0 0.1 GO:0033122 negative regulation of purine nucleotide catabolic process(GO:0033122)
0.0 0.2 GO:0045585 regulation of cytotoxic T cell differentiation(GO:0045583) positive regulation of cytotoxic T cell differentiation(GO:0045585)
0.0 0.3 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
0.0 0.3 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.0 0.1 GO:0071707 immunoglobulin heavy chain V-D-J recombination(GO:0071707)
0.0 0.6 GO:0046697 decidualization(GO:0046697)
0.0 0.1 GO:0035700 immune complex clearance by monocytes and macrophages(GO:0002436) astrocyte chemotaxis(GO:0035700) regulation of immune complex clearance by monocytes and macrophages(GO:0090264) positive regulation of immune complex clearance by monocytes and macrophages(GO:0090265) negative regulation of eosinophil activation(GO:1902567) positive regulation of CD8-positive, alpha-beta T cell extravasation(GO:2000451) regulation of astrocyte chemotaxis(GO:2000458)
0.0 0.1 GO:1904970 brush border assembly(GO:1904970)
0.0 0.5 GO:0006465 signal peptide processing(GO:0006465)
0.0 0.5 GO:0038092 nodal signaling pathway(GO:0038092)
0.0 0.3 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.0 0.2 GO:0030242 pexophagy(GO:0030242)
0.0 0.6 GO:0030575 nuclear body organization(GO:0030575)
0.0 0.1 GO:0032241 positive regulation of nucleobase-containing compound transport(GO:0032241)
0.0 0.8 GO:1902175 regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902175)
0.0 0.1 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.0 0.1 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.0 0.7 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.5 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.1 GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302) mesodermal to mesenchymal transition involved in gastrulation(GO:0060809)
0.0 0.1 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.0 0.1 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
0.0 0.4 GO:0030252 growth hormone secretion(GO:0030252)
0.0 0.2 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.0 0.3 GO:2000060 positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000060)
0.0 0.2 GO:0010572 positive regulation of platelet activation(GO:0010572)
0.0 0.8 GO:1903008 organelle disassembly(GO:1903008)
0.0 0.2 GO:0019336 phenol-containing compound catabolic process(GO:0019336)
0.0 0.3 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.0 0.2 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.0 0.1 GO:1903895 negative regulation of IRE1-mediated unfolded protein response(GO:1903895)
0.0 0.2 GO:0043970 histone H3-K9 acetylation(GO:0043970)
0.0 0.3 GO:0097091 synaptic vesicle clustering(GO:0097091)
0.0 0.1 GO:2000628 regulation of miRNA metabolic process(GO:2000628)
0.0 0.2 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.2 GO:0002024 diet induced thermogenesis(GO:0002024)
0.0 0.1 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.2 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.3 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.2 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.0 GO:0044154 histone H3-K14 acetylation(GO:0044154)
0.0 0.3 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.1 GO:0030423 targeting of mRNA for destruction involved in RNA interference(GO:0030423)
0.0 0.5 GO:1903146 regulation of mitophagy(GO:1903146)
0.0 0.2 GO:0001675 acrosome assembly(GO:0001675)
0.0 0.3 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 0.1 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 1.0 GO:0000045 autophagosome assembly(GO:0000045)
0.0 0.0 GO:0045660 positive regulation of neutrophil differentiation(GO:0045660)
0.0 0.1 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.0 0.0 GO:0021506 anterior neuropore closure(GO:0021506) neuropore closure(GO:0021995)
0.0 0.3 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.0 GO:0014053 negative regulation of gamma-aminobutyric acid secretion(GO:0014053)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0036488 CHOP-C/EBP complex(GO:0036488)
0.1 1.1 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.1 0.8 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.1 0.5 GO:0033010 paranodal junction(GO:0033010)
0.1 0.6 GO:0042382 paraspeckles(GO:0042382)
0.1 0.5 GO:0044530 supraspliceosomal complex(GO:0044530)
0.1 0.4 GO:1990111 spermatoproteasome complex(GO:1990111)
0.1 0.2 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.1 1.1 GO:0031143 pseudopodium(GO:0031143)
0.1 0.5 GO:0005787 signal peptidase complex(GO:0005787)
0.1 0.3 GO:0090498 extrinsic component of Golgi membrane(GO:0090498)
0.1 0.3 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.1 0.3 GO:0030870 Mre11 complex(GO:0030870)
0.1 0.3 GO:1990769 proximal neuron projection(GO:1990769)
0.0 0.9 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.2 GO:0031673 H zone(GO:0031673)
0.0 0.4 GO:0071141 SMAD protein complex(GO:0071141)
0.0 0.2 GO:0044308 axonal spine(GO:0044308)
0.0 0.3 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 1.1 GO:0016460 myosin II complex(GO:0016460)
0.0 0.1 GO:0044194 cytolytic granule(GO:0044194)
0.0 0.5 GO:0000421 autophagosome membrane(GO:0000421)
0.0 0.4 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.3 GO:0043219 lateral loop(GO:0043219)
0.0 2.5 GO:0030315 T-tubule(GO:0030315)
0.0 0.4 GO:0044754 autolysosome(GO:0044754)
0.0 0.2 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.2 GO:0045098 type III intermediate filament(GO:0045098)
0.0 1.1 GO:0005776 autophagosome(GO:0005776)
0.0 0.1 GO:0099522 region of cytosol(GO:0099522) postsynaptic cytosol(GO:0099524)
0.0 0.3 GO:0090543 Flemming body(GO:0090543)
0.0 0.6 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.3 GO:0032156 septin cytoskeleton(GO:0032156)
0.0 0.5 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 1.7 GO:0008076 voltage-gated potassium channel complex(GO:0008076)
0.0 0.3 GO:0000124 SAGA complex(GO:0000124)
0.0 1.5 GO:0043198 dendritic shaft(GO:0043198)
0.0 0.3 GO:0043196 varicosity(GO:0043196)
0.0 0.2 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.0 0.1 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 0.2 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.2 GO:0033391 chromatoid body(GO:0033391)
0.0 0.1 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.2 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.0 GO:0060053 neurofilament cytoskeleton(GO:0060053)
0.0 0.2 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
0.3 0.9 GO:0031750 D3 dopamine receptor binding(GO:0031750) D5 dopamine receptor binding(GO:0031752)
0.2 0.6 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.2 0.8 GO:0033883 pyridoxal phosphatase activity(GO:0033883)
0.2 1.2 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.2 0.5 GO:0035939 microsatellite binding(GO:0035939)
0.2 0.8 GO:0004994 somatostatin receptor activity(GO:0004994)
0.2 0.6 GO:0048763 calcium-induced calcium release activity(GO:0048763)
0.1 0.6 GO:0004921 interleukin-11 receptor activity(GO:0004921) interleukin-11 binding(GO:0019970)
0.1 0.4 GO:0035500 MH2 domain binding(GO:0035500)
0.1 0.5 GO:0042903 tubulin deacetylase activity(GO:0042903)
0.1 0.5 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.1 0.5 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.1 0.8 GO:0005047 signal recognition particle binding(GO:0005047)
0.1 0.5 GO:2001070 starch binding(GO:2001070)
0.1 0.4 GO:0046923 ER retention sequence binding(GO:0046923)
0.1 0.6 GO:0001069 regulatory region RNA binding(GO:0001069)
0.1 0.9 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.1 0.3 GO:0016501 prostacyclin receptor activity(GO:0016501)
0.1 0.3 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.1 0.6 GO:0016892 endoribonuclease activity, producing 3'-phosphomonoesters(GO:0016892)
0.1 0.9 GO:0051870 methotrexate binding(GO:0051870)
0.1 0.3 GO:0001225 RNA polymerase II transcription coactivator binding(GO:0001225)
0.1 0.3 GO:0004698 calcium-dependent protein kinase C activity(GO:0004698)
0.1 0.3 GO:0004104 cholinesterase activity(GO:0004104)
0.1 1.9 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.1 0.3 GO:0070976 TIR domain binding(GO:0070976)
0.1 0.3 GO:0043682 copper-exporting ATPase activity(GO:0004008) copper-transporting ATPase activity(GO:0043682)
0.1 0.2 GO:0042015 interleukin-20 binding(GO:0042015)
0.1 0.4 GO:0015288 porin activity(GO:0015288)
0.1 0.9 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 0.3 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.1 0.2 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.1 0.4 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.1 0.4 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.3 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.0 0.3 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.0 0.2 GO:0004565 beta-galactosidase activity(GO:0004565)
0.0 0.3 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.1 GO:0031687 A2A adenosine receptor binding(GO:0031687)
0.0 0.2 GO:0017050 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.0 0.4 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 2.3 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 0.3 GO:0003964 telomerase activity(GO:0003720) RNA-directed DNA polymerase activity(GO:0003964)
0.0 0.1 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.0 0.9 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.1 GO:0008859 exoribonuclease II activity(GO:0008859)
0.0 0.5 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 0.2 GO:0005113 patched binding(GO:0005113)
0.0 0.1 GO:0035717 chemokine (C-C motif) ligand 7 binding(GO:0035717)
0.0 0.2 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0 0.5 GO:0001013 RNA polymerase I regulatory region DNA binding(GO:0001013)
0.0 0.3 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.2 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 0.7 GO:0070001 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.1 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.0 0.2 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.0 2.1 GO:0005249 voltage-gated potassium channel activity(GO:0005249)
0.0 0.3 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993) serotonin binding(GO:0051378)
0.0 1.2 GO:0005109 frizzled binding(GO:0005109)
0.0 0.5 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.8 GO:0070566 adenylyltransferase activity(GO:0070566)
0.0 0.3 GO:0031386 protein tag(GO:0031386)
0.0 1.0 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.1 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.0 0.1 GO:0016401 palmitoyl-CoA oxidase activity(GO:0016401)
0.0 0.2 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.8 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.5 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.9 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.3 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.7 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.3 GO:0008392 arachidonic acid epoxygenase activity(GO:0008392)
0.0 0.1 GO:0089720 caspase binding(GO:0089720)
0.0 0.7 GO:0005112 Notch binding(GO:0005112)
0.0 0.2 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.2 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.2 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 0.6 GO:0008009 chemokine activity(GO:0008009)
0.0 0.2 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.2 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.3 GO:0051920 peroxiredoxin activity(GO:0051920)
0.0 0.1 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.0 0.2 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.3 GO:0001056 RNA polymerase III activity(GO:0001056)
0.0 0.1 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 0.9 GO:0001190 transcriptional activator activity, RNA polymerase II transcription factor binding(GO:0001190) transcriptional repressor activity, RNA polymerase II activating transcription factor binding(GO:0098811)
0.0 0.2 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.1 GO:0032557 pyrimidine ribonucleotide binding(GO:0032557)
0.0 0.5 GO:0042162 telomeric DNA binding(GO:0042162)
0.0 0.1 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.1 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.1 GO:0004576 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.1 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.5 GO:0015175 neutral amino acid transmembrane transporter activity(GO:0015175)
0.0 0.1 GO:0030274 LIM domain binding(GO:0030274)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.5 PID IGF1 PATHWAY IGF1 pathway
0.0 1.9 PID ARF6 PATHWAY Arf6 signaling events
0.0 0.7 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.5 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.4 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.3 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 1.9 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.3 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.3 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 1.4 PID LYSOPHOSPHOLIPID PATHWAY LPA receptor mediated events
0.0 0.8 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 0.4 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 0.5 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.2 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 0.6 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 0.8 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.3 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.0 0.1 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.9 PID P73PATHWAY p73 transcription factor network
0.0 1.0 WNT SIGNALING Genes related to Wnt-mediated signal transduction

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.5 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 2.1 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.4 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.8 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0 1.9 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.6 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.5 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.0 2.3 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.3 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.3 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.3 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 0.7 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.4 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.5 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 1.2 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.9 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.4 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.3 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 0.9 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.4 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.2 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.2 REACTOME GLUCAGON SIGNALING IN METABOLIC REGULATION Genes involved in Glucagon signaling in metabolic regulation
0.0 0.3 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 2.6 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 0.3 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.2 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.2 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.3 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 1.0 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.2 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.1 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.5 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.3 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.2 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.0 0.5 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.1 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.0 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins