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2D miR_HR1_12

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Results for E2f1

Z-value: 6.14

Motif logo

Transcription factors associated with E2f1

Gene Symbol Gene ID Gene Info
ENSMUSG00000027490.11 E2F transcription factor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
E2f1mm10_v2_chr2_-_154569845_1545698920.973.7e-07Click!

Activity profile of E2f1 motif

Sorted Z-values of E2f1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr17_+_56303396 17.49 ENSMUST00000113038.1
ubiquitin-like, containing PHD and RING finger domains, 1
chr4_-_89294608 17.04 ENSMUST00000107131.1
cyclin-dependent kinase inhibitor 2A
chr17_+_56303321 16.72 ENSMUST00000001258.8
ubiquitin-like, containing PHD and RING finger domains, 1
chr5_+_45669907 16.58 ENSMUST00000117396.1
non-SMC condensin I complex, subunit G
chr4_+_126556935 16.58 ENSMUST00000048391.8
claspin
chr1_-_20820213 15.81 ENSMUST00000053266.9
minichromosome maintenance deficient 3 (S. cerevisiae)
chr13_-_55329723 14.82 ENSMUST00000021941.7
Max dimerization protein 3
chr9_+_65890237 13.96 ENSMUST00000045802.6
RIKEN cDNA 2810417H13 gene
chr1_-_191575534 13.62 ENSMUST00000027933.5
denticleless homolog (Drosophila)
chr7_+_102441685 13.05 ENSMUST00000033283.9
ribonucleotide reductase M1
chr11_+_98907801 12.85 ENSMUST00000092706.6
cell division cycle 6
chr15_-_82212796 12.67 ENSMUST00000179269.1
expressed sequence AI848285
chr16_+_93883895 11.94 ENSMUST00000023666.4
ENSMUST00000117099.1
ENSMUST00000142316.1
chromatin assembly factor 1, subunit B (p60)
chr1_+_180641330 11.93 ENSMUST00000085804.5
lin-9 homolog (C. elegans)
chr14_-_47276790 11.67 ENSMUST00000111792.1
ENSMUST00000111791.1
ENSMUST00000111790.1
WD repeat and HMG-box DNA binding protein 1
chr8_+_71406003 11.67 ENSMUST00000119976.1
ENSMUST00000120725.1
ankyrin repeat and LEM domain containing 1
chr12_+_69168808 11.37 ENSMUST00000110621.1
leucine rich repeat protein 1
chr15_+_55557399 11.23 ENSMUST00000022998.7
Mdm2, transformed 3T3 cell double minute p53 binding protein
chr12_+_116405397 11.18 ENSMUST00000084828.3
non-SMC condensin II complex, subunit G2
chr10_+_110745433 10.83 ENSMUST00000174857.1
ENSMUST00000073781.5
ENSMUST00000173471.1
ENSMUST00000173634.1
E2F transcription factor 7
chr12_+_24708241 10.59 ENSMUST00000020980.5
ribonucleotide reductase M2
chr10_+_128232065 10.37 ENSMUST00000055539.4
ENSMUST00000105244.1
ENSMUST00000105243.2
ENSMUST00000125289.1
ENSMUST00000105242.1
timeless circadian clock 1
chr17_-_35516780 10.12 ENSMUST00000160885.1
ENSMUST00000159009.1
ENSMUST00000161012.1
transcription factor 19
chr7_+_13278778 10.04 ENSMUST00000098814.4
ENSMUST00000146998.1
ENSMUST00000185145.1
ligase I, DNA, ATP-dependent
chr13_-_100775844 9.84 ENSMUST00000075550.3
centromere protein H
chr9_-_61946768 9.80 ENSMUST00000034815.7
kinesin family member 23
chr6_+_134929118 9.75 ENSMUST00000185152.1
ENSMUST00000184504.1
RP23-45G16.5
chr5_-_138171248 9.69 ENSMUST00000153867.1
minichromosome maintenance deficient 7 (S. cerevisiae)
chr15_+_55557575 9.69 ENSMUST00000170046.1
Mdm2, transformed 3T3 cell double minute p53 binding protein
chr15_-_78773452 9.63 ENSMUST00000018313.5
MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr4_+_126556994 9.60 ENSMUST00000147675.1
claspin
chrX_-_111463149 9.58 ENSMUST00000096348.3
ENSMUST00000113428.2
ribosomal protein S6 kinase polypeptide 6
chr6_+_134929089 9.44 ENSMUST00000183867.1
ENSMUST00000184991.1
ENSMUST00000183905.1
RP23-45G16.5
chr5_+_123749696 9.42 ENSMUST00000031366.7
kinetochore associated 1
chr8_+_75109528 9.34 ENSMUST00000164309.1
minichromosome maintenance deficient 5, cell division cycle 46 (S. cerevisiae)
chr4_+_115000156 9.18 ENSMUST00000030490.6
Scl/Tal1 interrupting locus
chr5_+_76840597 9.12 ENSMUST00000120639.2
ENSMUST00000163347.1
ENSMUST00000121851.1
RIKEN cDNA C530008M17 gene
chr2_+_163054682 8.99 ENSMUST00000018005.3
myeloblastosis oncogene-like 2
chrY_+_90784738 8.78 ENSMUST00000179483.1
erythroid differentiation regulator 1
chr16_-_4559720 8.78 ENSMUST00000005862.7
transcription factor AP4
chrX_+_134059315 8.55 ENSMUST00000144483.1
cleavage stimulation factor, 3' pre-RNA subunit 2
chr4_+_52439235 8.50 ENSMUST00000117280.1
ENSMUST00000102915.3
ENSMUST00000142227.1
structural maintenance of chromosomes 2
chr15_-_58135047 8.44 ENSMUST00000038194.3
ATPase family, AAA domain containing 2
chr9_+_106477269 8.39 ENSMUST00000047721.8
RRP9, small subunit (SSU) processome component, homolog (yeast)
chr13_-_47105790 8.12 ENSMUST00000129352.1
DEK oncogene (DNA binding)
chr5_-_138170992 7.98 ENSMUST00000139983.1
minichromosome maintenance deficient 7 (S. cerevisiae)
chr16_-_15637277 7.87 ENSMUST00000023353.3
minichromosome maintenance deficient 4 homolog (S. cerevisiae)
chr6_+_113531675 7.85 ENSMUST00000036340.5
ENSMUST00000101051.2
Fanconi anemia, complementation group D2
chr4_+_24496434 7.83 ENSMUST00000108222.2
ENSMUST00000138567.2
ENSMUST00000050446.6
MMS22-like, DNA repair protein
chr16_-_23127702 7.83 ENSMUST00000115338.1
ENSMUST00000115337.1
ENSMUST00000023598.8
replication factor C (activator 1) 4
chr16_+_37011758 7.55 ENSMUST00000071452.5
ENSMUST00000054034.6
polymerase (DNA directed), theta
chrX_-_111463103 7.50 ENSMUST00000137712.2
ribosomal protein S6 kinase polypeptide 6
chr7_-_48881596 7.49 ENSMUST00000119223.1
E2F transcription factor 8
chr7_+_141475459 7.47 ENSMUST00000138092.1
ENSMUST00000146305.1
tetraspanin 4
chr17_-_71526819 7.39 ENSMUST00000024851.9
NDC80 homolog, kinetochore complex component (S. cerevisiae)
chr6_-_126939524 7.28 ENSMUST00000144954.1
ENSMUST00000112221.1
ENSMUST00000112220.1
RAD51 associated protein 1
chr11_+_103649498 7.24 ENSMUST00000057870.2
reprimo-like
chr17_-_29264115 7.22 ENSMUST00000024802.8
peptidylprolyl isomerase (cyclophilin)-like 1
chr9_-_97018823 7.20 ENSMUST00000055433.4
splA/ryanodine receptor domain and SOCS box containing 4
chr7_-_48881032 7.19 ENSMUST00000058745.8
E2F transcription factor 8
chr1_+_191063001 7.17 ENSMUST00000076952.5
ENSMUST00000139340.1
ENSMUST00000078259.6
NSL1, MIND kinetochore complex component, homolog (S. cerevisiae)
chr1_-_128359610 7.03 ENSMUST00000027601.4
minichromosome maintenance deficient 6 (MIS5 homolog, S. pombe) (S. cerevisiae)
chr16_-_57606816 6.98 ENSMUST00000114371.3
cms small ribosomal subunit 1
chrX_+_71556874 6.91 ENSMUST00000123100.1
high mobility group box 3
chr8_+_105348163 6.87 ENSMUST00000073149.5
solute carrier family 9 (sodium/hydrogen exchanger), member 5
chr11_-_101551837 6.84 ENSMUST00000017290.4
breast cancer 1
chr16_-_18811615 6.76 ENSMUST00000096990.3
cell division cycle 45
chrX_+_71555918 6.75 ENSMUST00000072699.6
ENSMUST00000114582.2
ENSMUST00000015361.4
ENSMUST00000088874.3
high mobility group box 3
chr19_-_9899450 6.72 ENSMUST00000025562.7
inner centromere protein
chr13_-_47106176 6.67 ENSMUST00000021807.6
ENSMUST00000135278.1
DEK oncogene (DNA binding)
chr15_-_55557748 6.62 ENSMUST00000172387.1
mitochondrial ribosomal protein L13
chr6_-_145076106 6.55 ENSMUST00000111742.1
ENSMUST00000048252.4
branched chain aminotransferase 1, cytosolic
chr18_+_4921662 6.50 ENSMUST00000143254.1
supervillin
chr4_+_128993224 6.47 ENSMUST00000030583.6
ENSMUST00000102604.4
adenylate kinase 2
chr10_-_128704978 6.46 ENSMUST00000026416.7
ENSMUST00000026415.7
cyclin-dependent kinase 2
chr14_+_31217850 6.43 ENSMUST00000090180.2
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3G
chr12_-_11265768 6.38 ENSMUST00000166117.1
Gen homolog 1, endonuclease (Drosophila)
chr4_+_115000174 6.28 ENSMUST00000129957.1
Scl/Tal1 interrupting locus
chr10_+_80356459 6.27 ENSMUST00000039836.8
ENSMUST00000105351.1
polo-like kinase 5
chr7_+_65862029 6.26 ENSMUST00000055576.5
ENSMUST00000098391.4
proprotein convertase subtilisin/kexin type 6
chr18_+_56707725 6.23 ENSMUST00000025486.8
lamin B1
chr14_-_67715585 6.22 ENSMUST00000163100.1
ENSMUST00000132705.1
ENSMUST00000124045.1
cell division cycle associated 2
chr12_+_117843873 6.14 ENSMUST00000176735.1
ENSMUST00000177339.1
cell division cycle associated 7 like
chr15_-_55090422 6.09 ENSMUST00000110231.1
ENSMUST00000023059.6
defective in sister chromatid cohesion 1 homolog (S. cerevisiae)
chr17_+_35841668 6.08 ENSMUST00000174124.1
mediator of DNA damage checkpoint 1
chr1_+_92831614 5.96 ENSMUST00000045970.6
glypican 1
chr12_+_24708984 5.91 ENSMUST00000154588.1
ribonucleotide reductase M2
chr16_+_10835046 5.88 ENSMUST00000037913.8
RMI2, RecQ mediated genome instability 2, homolog (S. cerevisiae)
chr2_+_139678178 5.86 ENSMUST00000184404.1
ENSMUST00000099307.3
isthmin 1 homolog (zebrafish)
chr5_-_138171813 5.86 ENSMUST00000155902.1
ENSMUST00000148879.1
minichromosome maintenance deficient 7 (S. cerevisiae)
chr11_-_82991137 5.83 ENSMUST00000138797.1
schlafen 9
chr6_-_47594967 5.78 ENSMUST00000081721.6
ENSMUST00000114618.1
ENSMUST00000114616.1
enhancer of zeste homolog 2 (Drosophila)
chr9_-_106656081 5.78 ENSMUST00000023959.7
glutamate receptor, metabotropic 2
chr2_-_119618455 5.77 ENSMUST00000123818.1
Opa interacting protein 5
chr3_+_40800013 5.77 ENSMUST00000026858.5
ENSMUST00000170825.1
polo-like kinase 4
chr1_+_172482199 5.77 ENSMUST00000135267.1
ENSMUST00000052629.6
ENSMUST00000111235.2
immunoglobulin superfamily, member 9
chr11_-_86201144 5.75 ENSMUST00000044423.3
BRCA1 interacting protein C-terminal helicase 1
chr17_+_35841491 5.74 ENSMUST00000082337.6
mediator of DNA damage checkpoint 1
chr15_+_100228229 5.68 ENSMUST00000171869.1
activating transcription factor 1
chr4_-_133968611 5.68 ENSMUST00000102552.1
high mobility group nucleosomal binding domain 2
chr11_-_34833631 5.65 ENSMUST00000093191.2
spindle apparatus coiled-coil protein 1
chr12_+_111271089 5.65 ENSMUST00000021707.6
amnionless
chr19_+_38931008 5.59 ENSMUST00000145051.1
helicase, lymphoid specific
chr3_+_40800054 5.59 ENSMUST00000168287.1
polo-like kinase 4
chr7_-_141443989 5.54 ENSMUST00000026580.5
leucine-rich and death domain containing
chr10_+_63100156 5.48 ENSMUST00000044059.3
atonal homolog 7 (Drosophila)
chr6_+_117916981 5.44 ENSMUST00000179478.1
heterogeneous nuclear ribonucleoprotein F
chr5_-_92435114 5.39 ENSMUST00000135112.1
nucleoporin 54
chr17_+_56304313 5.38 ENSMUST00000113035.1
ENSMUST00000113039.2
ENSMUST00000142387.1
ubiquitin-like, containing PHD and RING finger domains, 1
chr8_+_46617426 5.35 ENSMUST00000093517.5
caspase 3
chr4_-_91372028 5.33 ENSMUST00000107110.1
ENSMUST00000008633.8
ENSMUST00000107118.1
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr10_+_128015157 5.32 ENSMUST00000178041.1
ENSMUST00000026461.7
DNA primase, p49 subunit
chr5_+_106964319 5.14 ENSMUST00000031221.5
ENSMUST00000117196.2
ENSMUST00000076467.6
cell division cycle 7 (S. cerevisiae)
chr2_+_72476159 5.14 ENSMUST00000102691.4
cell division cycle associated 7
chr19_+_38930909 5.12 ENSMUST00000025965.5
helicase, lymphoid specific
chr8_-_53638945 5.12 ENSMUST00000047768.4
nei like 3 (E. coli)
chr2_+_119618717 5.12 ENSMUST00000028771.7
nucleolar and spindle associated protein 1
chr5_+_120649188 5.08 ENSMUST00000156722.1
RAS protein activator like 1 (GAP1 like)
chr2_-_30801698 5.06 ENSMUST00000050003.8
RIKEN cDNA 1700001O22 gene
chr4_+_11558914 5.06 ENSMUST00000178703.1
ENSMUST00000095145.5
ENSMUST00000108306.2
ENSMUST00000070755.6
RAD54 homolog B (S. cerevisiae)
chr11_+_80089385 5.04 ENSMUST00000108239.1
ENSMUST00000017694.5
ATPase family, AAA domain containing 5
chr8_-_78508876 5.01 ENSMUST00000049245.7
RNA binding motif protein, X linked-like-1
chr7_-_44548733 4.99 ENSMUST00000145956.1
ENSMUST00000049343.8
polymerase (DNA directed), delta 1, catalytic subunit
chr3_-_73056943 4.98 ENSMUST00000059407.7
SLIT and NTRK-like family, member 3
chr12_+_117843489 4.97 ENSMUST00000021592.9
cell division cycle associated 7 like
chr5_-_138172383 4.96 ENSMUST00000000505.9
minichromosome maintenance deficient 7 (S. cerevisiae)
chr17_+_56040350 4.94 ENSMUST00000002914.8
chromatin assembly factor 1, subunit A (p150)
chr11_-_11808923 4.89 ENSMUST00000109664.1
ENSMUST00000150714.1
ENSMUST00000047689.4
ENSMUST00000171938.1
ENSMUST00000171080.1
fidgetin-like 1
chr4_+_108579445 4.89 ENSMUST00000102744.3
origin recognition complex, subunit 1
chr12_+_8771405 4.88 ENSMUST00000171158.1
syndecan 1
chr11_-_97629685 4.85 ENSMUST00000052281.4
RIKEN cDNA E130012A19 gene
chr2_+_72476225 4.82 ENSMUST00000157019.1
cell division cycle associated 7
chr4_-_116123618 4.80 ENSMUST00000102704.3
ENSMUST00000102705.3
RAD54 like (S. cerevisiae)
chrX_-_93632113 4.77 ENSMUST00000006856.2
polymerase (DNA directed), alpha 1
chr1_+_172481788 4.77 ENSMUST00000127052.1
immunoglobulin superfamily, member 9
chr19_-_10203880 4.74 ENSMUST00000142241.1
ENSMUST00000116542.2
ENSMUST00000025651.5
ENSMUST00000156291.1
flap structure specific endonuclease 1
chr4_+_89137122 4.70 ENSMUST00000058030.7
methylthioadenosine phosphorylase
chr12_+_8771317 4.68 ENSMUST00000020911.7
syndecan 1
chr7_+_141475240 4.67 ENSMUST00000026585.7
tetraspanin 4
chr17_-_35838208 4.64 ENSMUST00000134978.2
tubulin, beta 5 class I
chr5_-_138171216 4.62 ENSMUST00000147920.1
minichromosome maintenance deficient 7 (S. cerevisiae)
chr10_-_128565827 4.56 ENSMUST00000131728.1
ENSMUST00000026425.6
proliferation-associated 2G4
chr4_-_133967893 4.56 ENSMUST00000100472.3
ENSMUST00000136327.1
high mobility group nucleosomal binding domain 2
chr5_+_115845229 4.56 ENSMUST00000137952.1
ENSMUST00000148245.1
citron
chr9_+_44084944 4.56 ENSMUST00000176416.1
ENSMUST00000065461.7
ubiquitin specific peptidase 2
chr1_-_33669745 4.53 ENSMUST00000027312.9
DNA primase, p58 subunit
chr2_+_152962485 4.52 ENSMUST00000099197.2
ENSMUST00000103155.3
tubulin tyrosine ligase-like family, member 9
chr8_-_111300222 4.52 ENSMUST00000038739.4
ring finger and WD repeat domain 3
chr6_+_117917281 4.49 ENSMUST00000180020.1
ENSMUST00000177570.1
heterogeneous nuclear ribonucleoprotein F
chr1_+_153425162 4.47 ENSMUST00000042373.5
Shc SH2-domain binding protein 1-like
chr8_-_35495487 4.47 ENSMUST00000033927.6
exoribonuclease 1
chr9_-_36726374 4.41 ENSMUST00000172702.2
ENSMUST00000172742.1
ENSMUST00000034625.5
checkpoint kinase 1
chrX_-_51681856 4.40 ENSMUST00000114871.1
heparan sulfate 6-O-sulfotransferase 2
chrX_-_51681703 4.36 ENSMUST00000088172.5
heparan sulfate 6-O-sulfotransferase 2
chr10_+_110920170 4.36 ENSMUST00000020403.5
cysteine and glycine-rich protein 2
chr5_-_8422582 4.33 ENSMUST00000168500.1
ENSMUST00000002368.9
DBF4 homolog (S. cerevisiae)
chr19_+_46075842 4.33 ENSMUST00000165017.1
nucleolar and coiled-body phosphoprotein 1
chr14_-_54554359 4.30 ENSMUST00000022784.8
HAUS augmin-like complex, subunit 4
chr17_-_35838259 4.27 ENSMUST00000001566.8
tubulin, beta 5 class I
chr8_-_48555846 4.23 ENSMUST00000110345.1
ENSMUST00000110343.1
teneurin transmembrane protein 3
chrX_-_111463043 4.22 ENSMUST00000065976.5
ribosomal protein S6 kinase polypeptide 6
chr2_-_125625065 4.20 ENSMUST00000089776.2
centrosomal protein 152
chr13_+_23581563 4.20 ENSMUST00000102968.1
histone cluster 1, H4d
chr5_-_8422695 4.19 ENSMUST00000171808.1
DBF4 homolog (S. cerevisiae)
chr7_-_127026479 4.18 ENSMUST00000032916.4
MYC-associated zinc finger protein (purine-binding transcription factor)
chr17_-_40935047 4.18 ENSMUST00000087114.3
centromere protein Q
chr5_-_151651216 4.17 ENSMUST00000038131.9
replication factor C (activator 1) 3
chrY_+_90785442 4.11 ENSMUST00000177591.1
ENSMUST00000177671.1
ENSMUST00000179077.1
erythroid differentiation regulator 1
chr10_+_111473186 4.09 ENSMUST00000065917.8
nucleosome assembly protein 1-like 1
chr9_-_123260776 4.09 ENSMUST00000068140.4
transmembrane protein 158
chr2_+_109280738 4.06 ENSMUST00000028527.7
kinesin family member 18A
chr10_+_39732099 4.00 ENSMUST00000019986.6
REV3-like, catalytic subunit of DNA polymerase zeta RAD54 like (S. cerevisiae)
chr13_+_54503779 3.99 ENSMUST00000121401.1
ENSMUST00000118072.1
ENSMUST00000159721.1
SUMO-interacting motifs containing 1
chr9_+_107551516 3.96 ENSMUST00000093786.2
ENSMUST00000122225.1
Ras association (RalGDS/AF-6) domain family member 1
chr11_+_69015911 3.94 ENSMUST00000021278.7
ENSMUST00000161455.1
ENSMUST00000116359.2
CTS telomere maintenance complex component 1
chr2_+_158768083 3.89 ENSMUST00000029183.2
family with sequence similarity 83, member D
chr2_+_71389239 3.86 ENSMUST00000028408.2
histone aminotransferase 1
chr17_+_35861343 3.86 ENSMUST00000172931.1
nurim (nuclear envelope membrane protein)
chr17_+_87672523 3.78 ENSMUST00000172855.1
mutS homolog 2 (E. coli)
chr8_-_123949201 3.78 ENSMUST00000044795.7
nucleoporin 133
chr11_+_76202084 3.78 ENSMUST00000169560.1
family with sequence similarity 57, member A
chrX_+_159372175 3.76 ENSMUST00000087143.6
eukaryotic translation initiation factor 1A, X-linked
chr4_-_133967235 3.75 ENSMUST00000123234.1
high mobility group nucleosomal binding domain 2
chr11_+_84179792 3.74 ENSMUST00000137500.2
ENSMUST00000130012.2
acetyl-Coenzyme A carboxylase alpha
chr4_+_11191726 3.73 ENSMUST00000029866.9
ENSMUST00000108324.3
cyclin E2
chr19_+_38097065 3.72 ENSMUST00000067098.6
free fatty acid receptor 4
chr3_+_88532314 3.72 ENSMUST00000172699.1
mex3 homolog A (C. elegans)
chr18_+_36760214 3.67 ENSMUST00000049323.7
WD repeat domain 55
chr7_+_28350652 3.65 ENSMUST00000082134.4
ribosomal protein S16
chr9_+_70679016 3.65 ENSMUST00000144537.1
a disintegrin and metallopeptidase domain 10
chr9_-_35116804 3.65 ENSMUST00000034537.6
ST3 beta-galactoside alpha-2,3-sialyltransferase 4
chr17_+_35861318 3.64 ENSMUST00000074259.8
ENSMUST00000174873.1
nurim (nuclear envelope membrane protein)
chr7_-_38107490 3.57 ENSMUST00000108023.3
cyclin E1
chr6_+_51470339 3.57 ENSMUST00000094623.3
chromobox 3
chr11_+_87595646 3.51 ENSMUST00000134216.1
myotubularin related protein 4
chr11_+_76202007 3.51 ENSMUST00000094014.3
family with sequence similarity 57, member A
chr2_+_24949747 3.46 ENSMUST00000028350.3
zinc finger, MYND domain containing 19
chr2_+_125247190 3.45 ENSMUST00000082122.7
deoxyuridine triphosphatase
chr9_+_83548309 3.42 ENSMUST00000113215.3
SH3 domain binding glutamic acid-rich protein like 2
chr5_-_92435219 3.41 ENSMUST00000038514.8
nucleoporin 54

Network of associatons between targets according to the STRING database.

First level regulatory network of E2f1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
8.5 25.5 GO:0032877 positive regulation of DNA endoreduplication(GO:0032877)
5.9 29.4 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089)
4.8 47.8 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
3.7 14.6 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
3.5 10.4 GO:1904975 response to bleomycin(GO:1904975) cellular response to bleomycin(GO:1904976)
3.4 17.0 GO:2000435 regulation of protein neddylation(GO:2000434) negative regulation of protein neddylation(GO:2000435)
3.4 50.3 GO:0010216 maintenance of DNA methylation(GO:0010216)
3.3 9.8 GO:0044837 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
2.9 8.8 GO:0036228 protein targeting to nuclear inner membrane(GO:0036228)
2.9 11.7 GO:0070829 heterochromatin maintenance(GO:0070829)
2.9 5.7 GO:1990918 double-strand break repair involved in meiotic recombination(GO:1990918)
2.7 13.7 GO:0045578 negative regulation of B cell differentiation(GO:0045578)
2.7 24.1 GO:1900264 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
2.6 10.4 GO:0045950 negative regulation of mitotic recombination(GO:0045950)
2.6 2.6 GO:0000019 regulation of mitotic recombination(GO:0000019)
2.6 18.1 GO:0098535 de novo centriole assembly(GO:0098535)
2.4 9.6 GO:1903553 positive regulation of extracellular exosome assembly(GO:1903553)
2.4 26.2 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
2.3 16.3 GO:2001032 regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
2.3 65.3 GO:0006270 DNA replication initiation(GO:0006270)
2.3 6.8 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
2.1 14.8 GO:0033567 DNA replication, Okazaki fragment processing(GO:0033567)
2.1 6.2 GO:0031662 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662)
2.0 36.2 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
2.0 6.0 GO:0099547 regulation of translation at synapse, modulating synaptic transmission(GO:0099547) regulation of translation at postsynapse, modulating synaptic transmission(GO:0099578) positive regulation of intracellular transport of viral material(GO:1901254)
2.0 6.0 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
1.9 24.7 GO:0019985 translesion synthesis(GO:0019985)
1.9 5.6 GO:0071707 immunoglobulin heavy chain V-D-J recombination(GO:0071707)
1.8 5.5 GO:0072734 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
1.8 9.1 GO:0030920 N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
1.8 3.5 GO:0010032 meiotic chromosome condensation(GO:0010032)
1.8 26.3 GO:0007076 mitotic chromosome condensation(GO:0007076)
1.7 1.7 GO:0090172 microtubule cytoskeleton organization involved in homologous chromosome segregation(GO:0090172)
1.7 5.0 GO:0045004 DNA replication proofreading(GO:0045004)
1.6 14.6 GO:0090267 positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267)
1.6 4.7 GO:0006166 purine ribonucleoside salvage(GO:0006166)
1.6 4.7 GO:0097360 chorionic trophoblast cell proliferation(GO:0097360) regulation of chorionic trophoblast cell proliferation(GO:1901382)
1.5 21.3 GO:2000381 negative regulation of mesoderm development(GO:2000381)
1.5 7.4 GO:0032902 nerve growth factor production(GO:0032902)
1.5 5.9 GO:0060265 positive regulation of respiratory burst involved in inflammatory response(GO:0060265)
1.5 8.8 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
1.4 15.5 GO:0033504 floor plate development(GO:0033504)
1.3 2.7 GO:0009162 deoxyribonucleoside monophosphate metabolic process(GO:0009162)
1.3 5.4 GO:0044268 multicellular organismal protein metabolic process(GO:0044268)
1.3 1.3 GO:0032240 negative regulation of nucleobase-containing compound transport(GO:0032240) negative regulation of RNA export from nucleus(GO:0046832)
1.3 3.9 GO:0002184 cytoplasmic translational termination(GO:0002184)
1.3 8.9 GO:0046060 dATP metabolic process(GO:0046060)
1.2 13.6 GO:0016446 somatic hypermutation of immunoglobulin genes(GO:0016446)
1.2 4.9 GO:0070318 positive regulation of G0 to G1 transition(GO:0070318)
1.2 1.2 GO:0002191 cap-dependent translational initiation(GO:0002191)
1.1 5.5 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
1.1 6.5 GO:0009098 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
1.0 4.1 GO:2001245 regulation of phosphatidylcholine biosynthetic process(GO:2001245)
1.0 5.0 GO:0006348 chromatin silencing at telomere(GO:0006348)
1.0 11.0 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
1.0 2.9 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
1.0 5.8 GO:0046654 tetrahydrofolate biosynthetic process(GO:0046654)
1.0 2.9 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
1.0 5.8 GO:0034080 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.9 2.8 GO:0051316 attachment of spindle microtubules to kinetochore involved in meiotic chromosome segregation(GO:0051316)
0.9 5.7 GO:0015889 cobalamin transport(GO:0015889)
0.9 9.3 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.9 15.8 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.9 3.7 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.9 2.8 GO:0002842 positive regulation of T cell mediated immune response to tumor cell(GO:0002842)
0.9 14.7 GO:0051383 kinetochore assembly(GO:0051382) kinetochore organization(GO:0051383)
0.9 9.1 GO:0036123 histone H3-K9 dimethylation(GO:0036123)
0.9 9.7 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.9 2.6 GO:0033566 gamma-tubulin complex localization(GO:0033566)
0.9 2.6 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.9 4.4 GO:0072711 cellular response to hydroxyurea(GO:0072711)
0.9 0.9 GO:0090309 positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.9 3.4 GO:0000379 tRNA-type intron splice site recognition and cleavage(GO:0000379)
0.9 10.3 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.8 3.4 GO:0044806 G-quadruplex DNA unwinding(GO:0044806)
0.8 16.7 GO:0031297 replication fork processing(GO:0031297)
0.8 0.8 GO:1902455 negative regulation of stem cell population maintenance(GO:1902455)
0.8 7.8 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.8 8.4 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.8 2.3 GO:0043397 corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397) positive regulation of corticotropin-releasing hormone secretion(GO:0051466) regulation of G-protein coupled receptor internalization(GO:1904020)
0.8 3.0 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.8 7.6 GO:0071459 protein localization to chromosome, centromeric region(GO:0071459)
0.8 2.3 GO:1903490 regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490)
0.7 2.2 GO:1904046 negative regulation of vascular endothelial growth factor production(GO:1904046)
0.7 7.2 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.7 3.6 GO:0042117 monocyte activation(GO:0042117)
0.7 4.3 GO:0007000 nucleolus organization(GO:0007000)
0.7 2.1 GO:0036446 myofibroblast differentiation(GO:0036446) regulation of myofibroblast differentiation(GO:1904760)
0.7 15.7 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.7 1.4 GO:2000328 regulation of T-helper 17 cell lineage commitment(GO:2000328)
0.7 5.0 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.7 2.1 GO:0071603 endothelial cell-cell adhesion(GO:0071603)
0.7 1.4 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.7 1.4 GO:0045013 carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
0.7 0.7 GO:0046101 hypoxanthine metabolic process(GO:0046100) hypoxanthine biosynthetic process(GO:0046101)
0.7 2.8 GO:0010724 regulation of definitive erythrocyte differentiation(GO:0010724)
0.7 20.3 GO:0040034 regulation of development, heterochronic(GO:0040034)
0.6 1.9 GO:1900739 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.6 0.6 GO:1904742 regulation of telomeric DNA binding(GO:1904742)
0.6 1.9 GO:1902162 regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162)
0.6 4.3 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.6 2.4 GO:0000212 meiotic spindle organization(GO:0000212)
0.6 7.2 GO:0000070 mitotic sister chromatid segregation(GO:0000070)
0.6 0.6 GO:0051542 elastin biosynthetic process(GO:0051542)
0.6 2.2 GO:0019042 viral latency(GO:0019042)
0.6 1.7 GO:0006336 DNA replication-independent nucleosome assembly(GO:0006336)
0.5 4.9 GO:0090399 replicative senescence(GO:0090399)
0.5 5.3 GO:0031125 rRNA 3'-end processing(GO:0031125)
0.5 3.1 GO:0060623 regulation of chromosome condensation(GO:0060623)
0.5 2.1 GO:0072365 regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072365)
0.5 9.8 GO:0008340 determination of adult lifespan(GO:0008340)
0.5 1.0 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.5 3.5 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.5 1.9 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.5 0.5 GO:0021965 spinal cord ventral commissure morphogenesis(GO:0021965)
0.5 3.8 GO:1904667 negative regulation of ubiquitin protein ligase activity(GO:1904667)
0.5 5.7 GO:0021554 optic nerve development(GO:0021554)
0.5 2.4 GO:0070535 histone H2A K63-linked ubiquitination(GO:0070535)
0.5 3.8 GO:0000972 transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972)
0.5 2.4 GO:0045876 positive regulation of sister chromatid cohesion(GO:0045876)
0.5 1.8 GO:0051305 chromosome movement towards spindle pole(GO:0051305)
0.5 1.4 GO:0017187 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.5 4.5 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.4 6.3 GO:0070673 response to interleukin-18(GO:0070673)
0.4 3.6 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.4 3.9 GO:1901162 serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162)
0.4 3.5 GO:0046599 regulation of centriole replication(GO:0046599)
0.4 2.2 GO:1903232 melanosome assembly(GO:1903232)
0.4 0.9 GO:0030997 regulation of centriole-centriole cohesion(GO:0030997)
0.4 1.7 GO:0018317 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.4 2.1 GO:1904690 regulation of cap-independent translational initiation(GO:1903677) positive regulation of cap-independent translational initiation(GO:1903679) regulation of cytoplasmic translational initiation(GO:1904688) positive regulation of cytoplasmic translational initiation(GO:1904690)
0.4 3.4 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.4 1.3 GO:0061300 cerebellum vasculature development(GO:0061300)
0.4 1.7 GO:0046294 formaldehyde catabolic process(GO:0046294)
0.4 1.3 GO:0009106 lipoate metabolic process(GO:0009106)
0.4 2.9 GO:0061091 regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
0.4 1.7 GO:1904800 regulation of neuron remodeling(GO:1904799) negative regulation of neuron remodeling(GO:1904800)
0.4 27.3 GO:0051225 spindle assembly(GO:0051225)
0.4 4.0 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.4 1.2 GO:1902512 positive regulation of apoptotic DNA fragmentation(GO:1902512)
0.4 0.4 GO:0006434 seryl-tRNA aminoacylation(GO:0006434)
0.4 1.2 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.4 0.4 GO:0072719 cellular response to cisplatin(GO:0072719)
0.4 2.3 GO:0006741 NADP biosynthetic process(GO:0006741)
0.4 2.3 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.4 1.5 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.4 1.1 GO:1902410 mitotic cytokinetic process(GO:1902410)
0.4 0.7 GO:0007418 ventral midline development(GO:0007418)
0.4 13.0 GO:0051310 metaphase plate congression(GO:0051310)
0.4 2.5 GO:0048102 autophagic cell death(GO:0048102)
0.4 2.8 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.4 8.5 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.3 0.7 GO:0010982 regulation of high-density lipoprotein particle clearance(GO:0010982)
0.3 1.4 GO:0006297 nucleotide-excision repair, DNA gap filling(GO:0006297)
0.3 3.8 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.3 1.7 GO:1902510 regulation of apoptotic DNA fragmentation(GO:1902510)
0.3 3.8 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.3 3.6 GO:0048304 positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.3 2.0 GO:0072697 protein localization to cell cortex(GO:0072697)
0.3 4.2 GO:0097264 self proteolysis(GO:0097264)
0.3 3.2 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.3 1.9 GO:0046112 nucleobase biosynthetic process(GO:0046112)
0.3 8.7 GO:0044342 type B pancreatic cell proliferation(GO:0044342)
0.3 2.9 GO:0010764 negative regulation of fibroblast migration(GO:0010764)
0.3 1.0 GO:2000384 regulation of ectoderm development(GO:2000383) negative regulation of ectoderm development(GO:2000384)
0.3 1.0 GO:0043134 hindgut contraction(GO:0043133) regulation of hindgut contraction(GO:0043134)
0.3 0.9 GO:0070459 prolactin secretion(GO:0070459)
0.3 1.3 GO:0009446 putrescine biosynthetic process(GO:0009446)
0.3 16.6 GO:0033045 regulation of sister chromatid segregation(GO:0033045)
0.3 10.9 GO:0006284 base-excision repair(GO:0006284)
0.3 1.5 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.3 3.7 GO:0006020 inositol metabolic process(GO:0006020)
0.3 1.8 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.3 2.4 GO:1904627 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.3 2.7 GO:0038203 TORC2 signaling(GO:0038203)
0.3 0.3 GO:0072368 regulation of lipid transport by negative regulation of transcription from RNA polymerase II promoter(GO:0072368)
0.3 0.6 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.3 1.2 GO:2000543 positive regulation of gastrulation(GO:2000543)
0.3 1.2 GO:0072369 regulation of lipid transport by regulation of transcription from RNA polymerase II promoter(GO:0072367) regulation of lipid transport by positive regulation of transcription from RNA polymerase II promoter(GO:0072369)
0.3 1.2 GO:0003360 brainstem development(GO:0003360)
0.3 0.6 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
0.3 2.0 GO:0036265 RNA (guanine-N7)-methylation(GO:0036265)
0.3 0.8 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.3 3.3 GO:0006353 DNA-templated transcription, termination(GO:0006353)
0.3 1.1 GO:0043987 histone H3-S10 phosphorylation(GO:0043987)
0.3 4.9 GO:0015732 prostaglandin transport(GO:0015732)
0.3 0.8 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.3 2.2 GO:0048251 elastic fiber assembly(GO:0048251)
0.3 1.1 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.3 1.8 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.3 1.8 GO:0034379 very-low-density lipoprotein particle assembly(GO:0034379)
0.3 3.9 GO:0099515 actin filament-based transport(GO:0099515)
0.3 8.3 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.3 6.2 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.3 4.4 GO:1904814 regulation of protein localization to chromosome, telomeric region(GO:1904814)
0.3 1.5 GO:1990928 response to amino acid starvation(GO:1990928)
0.3 2.0 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.2 2.0 GO:0006362 transcription elongation from RNA polymerase I promoter(GO:0006362)
0.2 2.2 GO:0051503 adenine nucleotide transport(GO:0051503)
0.2 4.9 GO:1903859 regulation of dendrite extension(GO:1903859)
0.2 1.9 GO:0046826 negative regulation of protein export from nucleus(GO:0046826)
0.2 1.2 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.2 6.0 GO:0043153 entrainment of circadian clock by photoperiod(GO:0043153)
0.2 6.1 GO:0000303 response to superoxide(GO:0000303)
0.2 1.2 GO:0097503 sialylation(GO:0097503)
0.2 1.6 GO:0045541 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.2 0.7 GO:1902174 positive regulation of keratinocyte apoptotic process(GO:1902174)
0.2 0.9 GO:0061152 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.2 0.7 GO:2000686 signal transduction by trans-phosphorylation(GO:0023016) regulation of rubidium ion transmembrane transporter activity(GO:2000686)
0.2 1.5 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.2 2.1 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.2 2.1 GO:0044539 long-chain fatty acid import(GO:0044539)
0.2 0.6 GO:0010825 positive regulation of centrosome duplication(GO:0010825)
0.2 0.6 GO:0035928 rRNA import into mitochondrion(GO:0035928)
0.2 1.5 GO:0097421 liver regeneration(GO:0097421)
0.2 2.3 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.2 1.8 GO:0018095 protein polyglutamylation(GO:0018095)
0.2 1.0 GO:0097237 cellular response to toxic substance(GO:0097237)
0.2 0.4 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.2 2.8 GO:0071157 negative regulation of cell cycle arrest(GO:0071157)
0.2 2.4 GO:0030224 monocyte differentiation(GO:0030224)
0.2 0.8 GO:0031145 anaphase-promoting complex-dependent catabolic process(GO:0031145)
0.2 1.6 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.2 0.8 GO:0031053 primary miRNA processing(GO:0031053)
0.2 0.6 GO:0009146 purine nucleoside triphosphate catabolic process(GO:0009146)
0.2 1.4 GO:1902514 regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1902514)
0.2 1.2 GO:0097473 cellular response to light intensity(GO:0071484) cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473)
0.2 1.4 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.2 0.4 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.2 2.1 GO:0001542 ovulation from ovarian follicle(GO:0001542)
0.2 2.6 GO:0048617 foregut morphogenesis(GO:0007440) embryonic foregut morphogenesis(GO:0048617)
0.2 1.9 GO:0032471 negative regulation of endoplasmic reticulum calcium ion concentration(GO:0032471)
0.2 2.4 GO:0031581 hemidesmosome assembly(GO:0031581)
0.2 13.3 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.2 2.2 GO:0060174 limb bud formation(GO:0060174)
0.2 0.2 GO:2000812 regulation of barbed-end actin filament capping(GO:2000812)
0.2 1.8 GO:0098703 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.2 0.7 GO:0072235 distal convoluted tubule development(GO:0072025) metanephric distal convoluted tubule development(GO:0072221) metanephric distal tubule development(GO:0072235)
0.2 8.0 GO:0035019 somatic stem cell population maintenance(GO:0035019)
0.2 1.4 GO:1902036 regulation of hematopoietic stem cell differentiation(GO:1902036)
0.2 2.0 GO:0070986 left/right axis specification(GO:0070986)
0.2 0.8 GO:1902570 protein localization to nucleolus(GO:1902570)
0.2 0.5 GO:0046351 disaccharide biosynthetic process(GO:0046351)
0.2 1.7 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.2 2.1 GO:0045947 negative regulation of translational initiation(GO:0045947)
0.2 2.8 GO:1901663 ubiquinone biosynthetic process(GO:0006744) quinone biosynthetic process(GO:1901663)
0.2 1.1 GO:0097151 positive regulation of inhibitory postsynaptic potential(GO:0097151)
0.2 2.4 GO:0098719 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.2 1.6 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.2 0.6 GO:0060215 primitive hemopoiesis(GO:0060215)
0.2 2.9 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.2 1.4 GO:1903350 response to dopamine(GO:1903350) cellular response to dopamine(GO:1903351)
0.2 1.0 GO:0048671 negative regulation of collateral sprouting(GO:0048671)
0.2 0.6 GO:0000460 maturation of 5.8S rRNA(GO:0000460)
0.2 1.3 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
0.2 2.1 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.2 2.2 GO:0032682 negative regulation of chemokine production(GO:0032682)
0.2 0.5 GO:0033182 regulation of histone ubiquitination(GO:0033182)
0.2 1.1 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
0.2 2.8 GO:0043046 DNA methylation involved in gamete generation(GO:0043046)
0.2 2.2 GO:1904294 positive regulation of ERAD pathway(GO:1904294)
0.2 0.6 GO:0034508 centromere complex assembly(GO:0034508)
0.2 0.9 GO:0044829 positive regulation by host of viral genome replication(GO:0044829)
0.2 0.6 GO:0021764 amygdala development(GO:0021764)
0.2 0.5 GO:0060715 syncytiotrophoblast cell differentiation involved in labyrinthine layer development(GO:0060715)
0.1 1.8 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.1 4.1 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.1 1.3 GO:0048170 positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.1 0.9 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.1 1.3 GO:0021527 spinal cord association neuron differentiation(GO:0021527)
0.1 0.9 GO:1904177 regulation of adipose tissue development(GO:1904177)
0.1 0.4 GO:0060155 platelet dense granule organization(GO:0060155)
0.1 0.7 GO:0051176 positive regulation of sulfur metabolic process(GO:0051176)
0.1 2.1 GO:0006817 phosphate ion transport(GO:0006817)
0.1 0.4 GO:2001025 positive regulation of response to drug(GO:2001025)
0.1 1.0 GO:0005513 detection of calcium ion(GO:0005513)
0.1 1.2 GO:0070933 histone H4 deacetylation(GO:0070933)
0.1 4.1 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.1 4.8 GO:0030517 negative regulation of axon extension(GO:0030517)
0.1 0.4 GO:0007529 establishment of synaptic specificity at neuromuscular junction(GO:0007529)
0.1 1.9 GO:0071420 cellular response to histamine(GO:0071420)
0.1 3.7 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.1 0.8 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.1 1.9 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.1 0.4 GO:0098974 postsynaptic actin cytoskeleton organization(GO:0098974)
0.1 0.8 GO:0006537 glutamate biosynthetic process(GO:0006537)
0.1 0.7 GO:0045292 mRNA cis splicing, via spliceosome(GO:0045292)
0.1 0.4 GO:0007060 male meiosis chromosome segregation(GO:0007060)
0.1 2.2 GO:0035994 response to muscle stretch(GO:0035994)
0.1 0.9 GO:0016266 O-glycan processing(GO:0016266)
0.1 1.2 GO:0045040 protein import into mitochondrial outer membrane(GO:0045040)
0.1 0.6 GO:1902035 positive regulation of hematopoietic stem cell proliferation(GO:1902035)
0.1 2.5 GO:0002347 response to tumor cell(GO:0002347)
0.1 0.8 GO:0061072 iris morphogenesis(GO:0061072)
0.1 0.5 GO:0035470 positive regulation of vascular wound healing(GO:0035470)
0.1 3.0 GO:0051894 positive regulation of focal adhesion assembly(GO:0051894)
0.1 0.6 GO:0090168 Golgi reassembly(GO:0090168)
0.1 2.0 GO:0016188 synaptic vesicle maturation(GO:0016188)
0.1 0.5 GO:0060830 ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
0.1 4.0 GO:0046677 response to antibiotic(GO:0046677)
0.1 10.7 GO:0071897 DNA biosynthetic process(GO:0071897)
0.1 0.3 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.1 0.8 GO:0036337 Fas signaling pathway(GO:0036337)
0.1 1.5 GO:0046931 pore complex assembly(GO:0046931)
0.1 5.1 GO:0030514 negative regulation of BMP signaling pathway(GO:0030514)
0.1 3.1 GO:0043666 regulation of phosphoprotein phosphatase activity(GO:0043666)
0.1 0.3 GO:0042275 error-free postreplication DNA repair(GO:0042275)
0.1 0.7 GO:0006116 NADH oxidation(GO:0006116)
0.1 3.4 GO:0006378 mRNA polyadenylation(GO:0006378)
0.1 1.2 GO:1900246 positive regulation of RIG-I signaling pathway(GO:1900246)
0.1 5.1 GO:0035307 positive regulation of protein dephosphorylation(GO:0035307)
0.1 5.1 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.1 0.4 GO:0045723 positive regulation of fatty acid biosynthetic process(GO:0045723)
0.1 0.4 GO:0021995 anterior neuropore closure(GO:0021506) neuropore closure(GO:0021995)
0.1 0.6 GO:0042118 endothelial cell activation(GO:0042118)
0.1 1.3 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.1 0.8 GO:0060124 positive regulation of growth hormone secretion(GO:0060124)
0.1 0.3 GO:0071314 cellular response to cocaine(GO:0071314)
0.1 1.0 GO:0045792 negative regulation of cell size(GO:0045792)
0.1 1.2 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.1 0.3 GO:0021759 globus pallidus development(GO:0021759)
0.1 1.4 GO:0035196 dsRNA fragmentation(GO:0031050) production of miRNAs involved in gene silencing by miRNA(GO:0035196) production of small RNA involved in gene silencing by RNA(GO:0070918)
0.1 0.4 GO:1900864 mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864)
0.1 2.5 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.1 0.2 GO:0000183 chromatin silencing at rDNA(GO:0000183)
0.1 0.7 GO:0046051 UTP biosynthetic process(GO:0006228) UTP metabolic process(GO:0046051)
0.1 0.5 GO:0051571 positive regulation of histone H3-K4 methylation(GO:0051571)
0.1 0.3 GO:0002326 B cell lineage commitment(GO:0002326)
0.1 0.7 GO:0035562 negative regulation of chromatin binding(GO:0035562)
0.1 0.4 GO:0032053 ciliary basal body organization(GO:0032053)
0.1 0.6 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.1 0.8 GO:0061727 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.1 0.4 GO:1905216 positive regulation of mRNA binding(GO:1902416) positive regulation of RNA binding(GO:1905216)
0.1 0.2 GO:0019676 ammonia assimilation cycle(GO:0019676)
0.1 3.1 GO:0060325 face morphogenesis(GO:0060325)
0.1 0.6 GO:0034145 positive regulation of toll-like receptor 4 signaling pathway(GO:0034145)
0.1 1.7 GO:0048011 neurotrophin TRK receptor signaling pathway(GO:0048011)
0.1 0.6 GO:0043117 positive regulation of vascular permeability(GO:0043117)
0.1 4.0 GO:0007019 microtubule depolymerization(GO:0007019)
0.1 0.4 GO:0070166 enamel mineralization(GO:0070166)
0.1 0.1 GO:0046985 positive regulation of hemoglobin biosynthetic process(GO:0046985)
0.1 1.1 GO:0043248 proteasome assembly(GO:0043248)
0.1 4.7 GO:0016126 sterol biosynthetic process(GO:0016126)
0.1 0.8 GO:0031290 retinal ganglion cell axon guidance(GO:0031290)
0.1 1.5 GO:0042755 eating behavior(GO:0042755)
0.1 0.5 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.1 0.9 GO:0006308 DNA catabolic process(GO:0006308)
0.1 1.2 GO:0043968 histone H2A acetylation(GO:0043968)
0.1 0.2 GO:1901842 negative regulation of high voltage-gated calcium channel activity(GO:1901842)
0.1 0.7 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.1 6.3 GO:0042254 ribosome biogenesis(GO:0042254)
0.1 1.0 GO:0039703 viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)
0.1 0.3 GO:0015788 UDP-N-acetylglucosamine transport(GO:0015788)
0.1 6.0 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.1 0.5 GO:0043923 positive regulation by host of viral transcription(GO:0043923)
0.1 0.5 GO:2000344 positive regulation of acrosome reaction(GO:2000344)
0.1 0.9 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.1 0.6 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.1 2.5 GO:1904894 positive regulation of JAK-STAT cascade(GO:0046427) positive regulation of STAT cascade(GO:1904894)
0.1 0.2 GO:1901979 regulation of inward rectifier potassium channel activity(GO:1901979)
0.1 0.4 GO:0015871 choline transport(GO:0015871)
0.1 0.4 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729)
0.1 0.8 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.1 0.3 GO:0010692 regulation of alkaline phosphatase activity(GO:0010692) negative regulation of alkaline phosphatase activity(GO:0010693)
0.1 0.3 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.1 0.6 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.1 0.9 GO:0006306 DNA alkylation(GO:0006305) DNA methylation(GO:0006306)
0.1 0.9 GO:0052646 alditol phosphate metabolic process(GO:0052646)
0.1 2.5 GO:0051966 regulation of synaptic transmission, glutamatergic(GO:0051966)
0.1 1.1 GO:0048854 brain morphogenesis(GO:0048854)
0.1 2.3 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.0 0.4 GO:0033327 Leydig cell differentiation(GO:0033327)
0.0 0.1 GO:1902237 positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902237)
0.0 1.7 GO:0043550 regulation of lipid kinase activity(GO:0043550)
0.0 0.1 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.0 1.3 GO:0033137 negative regulation of peptidyl-serine phosphorylation(GO:0033137)
0.0 1.1 GO:0032094 response to food(GO:0032094)
0.0 0.1 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0 1.9 GO:0061077 chaperone-mediated protein folding(GO:0061077)
0.0 2.0 GO:0043966 histone H3 acetylation(GO:0043966)
0.0 0.6 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.0 0.6 GO:0042407 cristae formation(GO:0042407)
0.0 1.3 GO:0006084 acetyl-CoA metabolic process(GO:0006084)
0.0 1.4 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 2.5 GO:0006367 transcription initiation from RNA polymerase II promoter(GO:0006367)
0.0 1.6 GO:2001022 positive regulation of response to DNA damage stimulus(GO:2001022)
0.0 0.9 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.0 1.3 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.0 0.4 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.3 GO:2000653 regulation of genetic imprinting(GO:2000653)
0.0 0.1 GO:0051964 negative regulation of synapse assembly(GO:0051964)
0.0 0.8 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 0.2 GO:1904936 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.0 0.0 GO:1904354 negative regulation of telomere capping(GO:1904354)
0.0 0.8 GO:0045070 positive regulation of viral genome replication(GO:0045070)
0.0 0.7 GO:0032007 negative regulation of TOR signaling(GO:0032007)
0.0 1.0 GO:0045103 intermediate filament-based process(GO:0045103)
0.0 0.4 GO:0032986 nucleosome disassembly(GO:0006337) protein-DNA complex disassembly(GO:0032986)
0.0 0.3 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.0 0.3 GO:0007343 egg activation(GO:0007343)
0.0 0.1 GO:0030091 protein repair(GO:0030091)
0.0 0.9 GO:0000184 nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:0000184)
0.0 0.3 GO:0033133 positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.0 0.6 GO:0007062 sister chromatid cohesion(GO:0007062)
0.0 0.1 GO:0006624 vacuolar protein processing(GO:0006624)
0.0 1.2 GO:0032981 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.5 GO:0021694 cerebellar Purkinje cell layer formation(GO:0021694)
0.0 0.6 GO:1902236 negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway(GO:1902236)
0.0 0.3 GO:0060746 parental behavior(GO:0060746)
0.0 1.3 GO:0003281 ventricular septum development(GO:0003281)
0.0 0.6 GO:0051016 barbed-end actin filament capping(GO:0051016)
0.0 0.0 GO:1904192 cholangiocyte apoptotic process(GO:1902488) regulation of cholangiocyte apoptotic process(GO:1904192) negative regulation of cholangiocyte apoptotic process(GO:1904193)
0.0 0.3 GO:0006012 galactose metabolic process(GO:0006012)
0.0 0.3 GO:0044381 glucose import in response to insulin stimulus(GO:0044381)
0.0 0.3 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.0 0.3 GO:0060216 definitive hemopoiesis(GO:0060216)
0.0 1.0 GO:0045814 negative regulation of gene expression, epigenetic(GO:0045814)
0.0 1.6 GO:0050728 negative regulation of inflammatory response(GO:0050728)
0.0 0.8 GO:0071398 cellular response to fatty acid(GO:0071398)
0.0 0.9 GO:0045669 positive regulation of osteoblast differentiation(GO:0045669)
0.0 0.1 GO:1902525 regulation of protein monoubiquitination(GO:1902525)
0.0 0.1 GO:0009235 cobalamin metabolic process(GO:0009235)
0.0 0.2 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.0 0.3 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.0 1.9 GO:0006457 protein folding(GO:0006457)
0.0 0.6 GO:0033344 cholesterol efflux(GO:0033344)
0.0 0.4 GO:1902259 regulation of delayed rectifier potassium channel activity(GO:1902259)
0.0 0.9 GO:0042752 regulation of circadian rhythm(GO:0042752)
0.0 0.1 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.0 0.3 GO:0010614 negative regulation of cardiac muscle hypertrophy(GO:0010614)
0.0 0.1 GO:1902477 defense response, incompatible interaction(GO:0009814) defense response to bacterium, incompatible interaction(GO:0009816) regulation of defense response to bacterium, incompatible interaction(GO:1902477)
0.0 1.5 GO:0006260 DNA replication(GO:0006260)
0.0 0.0 GO:1902894 cellular response to lithium ion(GO:0071285) negative regulation of pri-miRNA transcription from RNA polymerase II promoter(GO:1902894)
0.0 0.1 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.1 GO:0019336 phenol-containing compound catabolic process(GO:0019336)
0.0 0.0 GO:0060948 cardiac vascular smooth muscle cell development(GO:0060948)
0.0 0.9 GO:0000910 cytokinesis(GO:0000910)
0.0 0.0 GO:1902530 regulation of protein linear polyubiquitination(GO:1902528) positive regulation of protein linear polyubiquitination(GO:1902530)
0.0 0.4 GO:0007588 excretion(GO:0007588)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
5.9 29.5 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
5.6 84.7 GO:0042555 MCM complex(GO:0042555)
5.6 16.9 GO:0033186 CAF-1 complex(GO:0033186)
4.4 13.1 GO:0097135 cyclin E2-CDK2 complex(GO:0097135)
4.0 39.8 GO:0000796 condensin complex(GO:0000796)
3.7 11.1 GO:0071920 cleavage body(GO:0071920)
3.4 10.3 GO:1990423 RZZ complex(GO:1990423)
3.0 17.8 GO:0005663 DNA replication factor C complex(GO:0005663)
3.0 17.8 GO:0098536 deuterosome(GO:0098536)
2.9 14.6 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
2.9 20.0 GO:0001652 granular component(GO:0001652)
2.3 6.8 GO:0005656 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
2.0 9.8 GO:0097149 centralspindlin complex(GO:0097149)
1.8 7.4 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
1.8 9.1 GO:0031523 Myb complex(GO:0031523)
1.8 10.9 GO:0000444 MIS12/MIND type complex(GO:0000444)
1.7 5.0 GO:0043625 delta DNA polymerase complex(GO:0043625)
1.6 10.9 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
1.5 6.0 GO:0019034 viral replication complex(GO:0019034) dendritic filopodium(GO:1902737)
1.4 7.2 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
1.4 8.4 GO:0031428 box C/D snoRNP complex(GO:0031428)
1.4 9.7 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
1.4 5.5 GO:1990590 ATF1-ATF4 transcription factor complex(GO:1990590)
1.3 13.3 GO:0044613 nuclear pore central transport channel(GO:0044613)
1.3 10.5 GO:0031415 NatA complex(GO:0031415)
1.3 3.9 GO:0018444 translation release factor complex(GO:0018444)
1.3 6.5 GO:0097226 sperm mitochondrial sheath(GO:0097226)
1.3 10.2 GO:0070652 HAUS complex(GO:0070652)
1.2 7.0 GO:0016035 zeta DNA polymerase complex(GO:0016035)
1.1 6.8 GO:0070531 BRCA1-A complex(GO:0070531)
1.0 9.4 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
1.0 4.2 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
1.0 1.0 GO:0030690 Noc1p-Noc2p complex(GO:0030690)
1.0 9.9 GO:0045298 tubulin complex(GO:0045298)
0.9 7.6 GO:0042382 paraspeckles(GO:0042382)
0.9 8.4 GO:0000801 central element(GO:0000801)
0.9 5.6 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.9 6.5 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.9 16.0 GO:0044453 nuclear membrane part(GO:0044453)
0.9 54.8 GO:0005657 replication fork(GO:0005657)
0.9 5.2 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.9 2.6 GO:0030870 Mre11 complex(GO:0030870)
0.8 5.0 GO:0044530 supraspliceosomal complex(GO:0044530)
0.8 4.1 GO:0005828 kinetochore microtubule(GO:0005828)
0.8 11.8 GO:0005652 nuclear lamina(GO:0005652)
0.8 3.9 GO:0034715 pICln-Sm protein complex(GO:0034715)
0.8 3.0 GO:0034709 methylosome(GO:0034709)
0.8 6.1 GO:0032300 mismatch repair complex(GO:0032300)
0.8 5.3 GO:0001740 Barr body(GO:0001740)
0.7 4.4 GO:0035976 AP1 complex(GO:0035976)
0.7 14.4 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.7 2.9 GO:1990421 subtelomeric heterochromatin(GO:1990421) nuclear subtelomeric heterochromatin(GO:1990707)
0.7 2.8 GO:0033553 rDNA heterochromatin(GO:0033553)
0.7 3.3 GO:0070876 SOSS complex(GO:0070876)
0.7 2.0 GO:0031533 mRNA cap methyltransferase complex(GO:0031533)
0.7 2.6 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.7 5.2 GO:0031264 death-inducing signaling complex(GO:0031264)
0.6 3.4 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.6 1.7 GO:0005673 transcription factor TFIIE complex(GO:0005673)
0.5 2.2 GO:0042827 platelet dense granule(GO:0042827)
0.5 6.4 GO:0072687 meiotic spindle(GO:0072687)
0.5 2.1 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.5 3.7 GO:0044354 pinosome(GO:0044352) macropinosome(GO:0044354)
0.5 4.7 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.5 3.0 GO:0097452 GAIT complex(GO:0097452)
0.5 2.0 GO:0000931 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.5 10.7 GO:0005721 pericentric heterochromatin(GO:0005721)
0.5 18.9 GO:0015030 Cajal body(GO:0015030)
0.5 1.4 GO:0035061 interchromatin granule(GO:0035061)
0.5 4.6 GO:0032797 SMN complex(GO:0032797)
0.5 6.4 GO:0000164 protein phosphatase type 1 complex(GO:0000164)
0.5 23.9 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.5 4.1 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.5 1.8 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.5 1.8 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.4 1.7 GO:0043293 apoptosome(GO:0043293)
0.4 2.1 GO:0071547 piP-body(GO:0071547)
0.4 0.8 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.4 2.8 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.4 3.9 GO:0097431 mitotic spindle pole(GO:0097431)
0.4 1.6 GO:0008623 CHRAC(GO:0008623)
0.4 1.2 GO:0097059 CNTFR-CLCF1 complex(GO:0097059)
0.4 10.7 GO:0051233 spindle midzone(GO:0051233)
0.3 1.4 GO:0000923 equatorial microtubule organizing center(GO:0000923)
0.3 2.1 GO:0005827 polar microtubule(GO:0005827)
0.3 56.8 GO:0000775 chromosome, centromeric region(GO:0000775)
0.3 3.8 GO:0031931 TORC1 complex(GO:0031931)
0.3 3.6 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.3 3.3 GO:0000783 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.3 1.0 GO:0042642 actomyosin, myosin complex part(GO:0042642)
0.3 3.2 GO:0016272 prefoldin complex(GO:0016272)
0.3 1.6 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.3 9.4 GO:0005876 spindle microtubule(GO:0005876)
0.3 0.9 GO:0031417 NatC complex(GO:0031417)
0.3 5.1 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.3 1.7 GO:0070847 core mediator complex(GO:0070847)
0.3 0.8 GO:0031074 nucleocytoplasmic shuttling complex(GO:0031074)
0.3 0.8 GO:0070877 microprocessor complex(GO:0070877) ribonuclease III complex(GO:1903095)
0.2 4.2 GO:0048188 Set1C/COMPASS complex(GO:0048188)
0.2 1.5 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.2 2.7 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.2 1.4 GO:0070761 pre-snoRNP complex(GO:0070761)
0.2 11.0 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.2 36.0 GO:0001650 fibrillar center(GO:0001650)
0.2 0.9 GO:0005826 actomyosin contractile ring(GO:0005826)
0.2 1.1 GO:0033010 paranodal junction(GO:0033010)
0.2 2.2 GO:0090576 RNA polymerase III transcription factor complex(GO:0090576)
0.2 7.0 GO:0030686 90S preribosome(GO:0030686)
0.2 6.9 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.2 4.5 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.2 19.8 GO:0017053 transcriptional repressor complex(GO:0017053)
0.2 19.8 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.2 1.5 GO:0072559 NLRP3 inflammasome complex(GO:0072559)
0.2 2.6 GO:0000930 gamma-tubulin complex(GO:0000930)
0.2 1.0 GO:0035189 Rb-E2F complex(GO:0035189)
0.2 5.2 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.2 2.5 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.2 2.3 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.2 10.2 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.2 2.4 GO:0097539 ciliary transition fiber(GO:0097539)
0.2 0.7 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.2 1.2 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.2 2.2 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.2 1.7 GO:0031616 spindle pole centrosome(GO:0031616)
0.2 1.3 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.2 0.6 GO:0005688 U6 snRNP(GO:0005688)
0.2 2.1 GO:0042788 polysomal ribosome(GO:0042788)
0.1 0.6 GO:0031084 BLOC-2 complex(GO:0031084)
0.1 6.7 GO:0045171 intercellular bridge(GO:0045171)
0.1 2.4 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.1 13.0 GO:0005681 spliceosomal complex(GO:0005681)
0.1 1.3 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.1 1.2 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.1 6.5 GO:0043034 costamere(GO:0043034)
0.1 2.2 GO:0031083 BLOC-1 complex(GO:0031083)
0.1 0.5 GO:1990696 USH2 complex(GO:1990696)
0.1 5.7 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.1 0.4 GO:0005608 laminin-3 complex(GO:0005608)
0.1 1.2 GO:0061574 ASAP complex(GO:0061574)
0.1 1.5 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.1 0.4 GO:1903349 omegasome membrane(GO:1903349)
0.1 17.9 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.1 1.3 GO:1904115 axon cytoplasm(GO:1904115)
0.1 4.6 GO:0002102 podosome(GO:0002102)
0.1 0.3 GO:1990716 axonemal central apparatus(GO:1990716)
0.1 0.8 GO:0000322 storage vacuole(GO:0000322)
0.1 1.0 GO:0061617 MICOS complex(GO:0061617)
0.1 2.1 GO:0035861 site of double-strand break(GO:0035861)
0.1 0.6 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.1 1.1 GO:0032040 small-subunit processome(GO:0032040)
0.1 1.1 GO:0044327 dendritic spine head(GO:0044327)
0.1 1.2 GO:0030014 CCR4-NOT complex(GO:0030014)
0.1 0.9 GO:0036156 inner dynein arm(GO:0036156)
0.1 1.4 GO:0032593 insulin-responsive compartment(GO:0032593)
0.1 8.6 GO:0005814 centriole(GO:0005814)
0.1 4.6 GO:0016235 aggresome(GO:0016235)
0.1 0.4 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.1 6.9 GO:0015934 large ribosomal subunit(GO:0015934)
0.1 5.6 GO:0034399 nuclear periphery(GO:0034399)
0.1 1.0 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.1 0.4 GO:0070776 H3 histone acetyltransferase complex(GO:0070775) MOZ/MORF histone acetyltransferase complex(GO:0070776)
0.1 0.6 GO:0000938 GARP complex(GO:0000938)
0.1 0.7 GO:0036194 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.1 1.9 GO:1902711 GABA-A receptor complex(GO:1902711)
0.1 0.3 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.1 0.4 GO:0044316 cone cell pedicle(GO:0044316)
0.1 1.2 GO:0090544 BAF-type complex(GO:0090544)
0.1 3.8 GO:0032154 cell division site(GO:0032153) cleavage furrow(GO:0032154) cell division site part(GO:0032155) cell surface furrow(GO:0097610)
0.1 0.6 GO:0000815 ESCRT III complex(GO:0000815)
0.1 17.3 GO:0005667 transcription factor complex(GO:0005667)
0.1 4.2 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.1 1.0 GO:0005637 nuclear inner membrane(GO:0005637)
0.1 0.4 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1 0.6 GO:0071203 WASH complex(GO:0071203)
0.1 52.6 GO:0005694 chromosome(GO:0005694)
0.1 2.3 GO:0030992 intraciliary transport particle B(GO:0030992)
0.1 0.3 GO:0031371 ubiquitin conjugating enzyme complex(GO:0031371)
0.1 1.3 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.1 1.0 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.1 1.3 GO:0030056 hemidesmosome(GO:0030056)
0.1 2.1 GO:0005840 ribosome(GO:0005840)
0.1 0.5 GO:0000138 Golgi trans cisterna(GO:0000138)
0.1 2.5 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.1 0.4 GO:0005642 annulate lamellae(GO:0005642)
0.1 3.0 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.1 4.3 GO:0031594 neuromuscular junction(GO:0031594)
0.1 1.0 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 3.9 GO:0000502 proteasome complex(GO:0000502)
0.1 11.3 GO:0043292 contractile fiber(GO:0043292)
0.1 5.2 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.1 4.1 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 0.7 GO:0044294 dendritic growth cone(GO:0044294)
0.1 2.5 GO:0005643 nuclear pore(GO:0005643)
0.1 0.3 GO:0045120 pronucleus(GO:0045120)
0.0 5.1 GO:0005759 mitochondrial matrix(GO:0005759)
0.0 0.5 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 1.9 GO:0000922 spindle pole(GO:0000922)
0.0 1.3 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.7 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 1.1 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.3 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 0.4 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 6.2 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 0.4 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.5 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.2 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.2 GO:0031143 pseudopodium(GO:0031143)
0.0 0.6 GO:0035869 ciliary transition zone(GO:0035869)
0.0 0.9 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.2 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.1 GO:0005784 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0 0.8 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 4.5 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.0 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.0 0.2 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.7 GO:0005811 lipid particle(GO:0005811)
0.0 1.7 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.1 GO:0097542 ciliary tip(GO:0097542)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
6.9 41.7 GO:0031493 nucleosomal histone binding(GO:0031493)
5.9 29.5 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
4.5 27.0 GO:0010997 anaphase-promoting complex binding(GO:0010997)
4.3 17.0 GO:0055105 ubiquitin-protein transferase inhibitor activity(GO:0055105)
3.2 9.6 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
3.1 15.5 GO:0043515 kinetochore binding(GO:0043515)
2.4 7.3 GO:0071207 histone pre-mRNA stem-loop binding(GO:0071207)
2.3 4.7 GO:0000405 bubble DNA binding(GO:0000405)
2.3 25.1 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
2.2 8.8 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
2.2 6.5 GO:0032137 guanine/thymine mispair binding(GO:0032137)
2.0 6.0 GO:0070052 collagen V binding(GO:0070052)
1.9 7.8 GO:0070087 chromo shadow domain binding(GO:0070087)
1.9 7.6 GO:0043142 single-stranded DNA-dependent ATPase activity(GO:0043142)
1.8 9.1 GO:1990190 peptide-glutamate-N-acetyltransferase activity(GO:1990190)
1.6 7.9 GO:0015616 DNA translocase activity(GO:0015616)
1.6 10.9 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
1.5 7.6 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
1.5 4.4 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
1.4 56.3 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
1.4 12.2 GO:0003909 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
1.3 3.8 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
1.2 1.2 GO:1990189 peptide-serine-N-acetyltransferase activity(GO:1990189)
1.2 16.0 GO:0003688 DNA replication origin binding(GO:0003688)
1.2 4.7 GO:0017108 5'-flap endonuclease activity(GO:0017108)
1.1 6.5 GO:0052656 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
1.1 5.4 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
1.1 3.2 GO:0009041 uridylate kinase activity(GO:0009041)
1.1 6.4 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
1.0 8.4 GO:0034511 U3 snoRNA binding(GO:0034511)
1.0 26.8 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
1.0 3.0 GO:0035605 peptidyl-cysteine S-nitrosylase activity(GO:0035605)
1.0 6.0 GO:0033592 RNA strand annealing activity(GO:0033592)
0.9 2.8 GO:0070139 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.9 3.6 GO:0047288 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836) monosialoganglioside sialyltransferase activity(GO:0047288)
0.9 8.8 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.8 8.4 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.8 2.4 GO:0071209 U7 snRNA binding(GO:0071209)
0.8 5.6 GO:0032184 SUMO polymer binding(GO:0032184)
0.8 2.3 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.7 2.2 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.7 2.9 GO:0016842 amidine-lyase activity(GO:0016842)
0.7 5.8 GO:0001640 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640)
0.7 3.6 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.7 6.3 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.7 2.1 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.7 2.8 GO:0000010 trans-hexaprenyltranstransferase activity(GO:0000010) trans-octaprenyltranstransferase activity(GO:0050347)
0.7 2.0 GO:0004482 mRNA (guanine-N7-)-methyltransferase activity(GO:0004482)
0.6 2.6 GO:0004488 methenyltetrahydrofolate cyclohydrolase activity(GO:0004477) methylenetetrahydrofolate dehydrogenase (NADP+) activity(GO:0004488)
0.6 1.9 GO:0004088 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.6 16.1 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.6 3.7 GO:0008527 taste receptor activity(GO:0008527)
0.6 5.5 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.6 1.8 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.6 1.8 GO:0015275 stretch-activated, cation-selective, calcium channel activity(GO:0015275)
0.6 6.5 GO:0004017 adenylate kinase activity(GO:0004017)
0.6 2.3 GO:0036468 aromatic-L-amino-acid decarboxylase activity(GO:0004058) L-dopa decarboxylase activity(GO:0036468)
0.6 3.4 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.6 2.3 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.6 1.7 GO:0018738 S-formylglutathione hydrolase activity(GO:0018738)
0.6 3.9 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.5 1.6 GO:0008311 double-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008311)
0.5 2.1 GO:0043758 acetate-CoA ligase (ADP-forming) activity(GO:0043758)
0.5 1.6 GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.5 4.1 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.5 7.6 GO:0035173 histone kinase activity(GO:0035173)
0.5 1.9 GO:0000150 recombinase activity(GO:0000150)
0.5 7.8 GO:0051010 microtubule plus-end binding(GO:0051010)
0.5 1.9 GO:0000700 mismatch base pair DNA N-glycosylase activity(GO:0000700)
0.5 2.9 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.5 0.5 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.5 2.9 GO:0046404 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.5 2.8 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.5 2.8 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.5 1.4 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.4 8.5 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.4 4.0 GO:0047429 nucleoside-triphosphate diphosphatase activity(GO:0047429)
0.4 7.2 GO:0038191 neuropilin binding(GO:0038191)
0.4 3.1 GO:0055104 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.4 2.7 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.4 13.0 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.4 5.6 GO:0098847 sequence-specific single stranded DNA binding(GO:0098847)
0.4 3.0 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.4 8.5 GO:0070182 DNA polymerase binding(GO:0070182)
0.4 1.6 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
0.4 2.4 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.4 1.2 GO:0001156 TFIIIC-class transcription factor binding(GO:0001156)
0.4 2.0 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.4 1.2 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.4 2.4 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.4 0.4 GO:0004828 serine-tRNA ligase activity(GO:0004828)
0.4 2.4 GO:0032027 myosin light chain binding(GO:0032027)
0.4 3.1 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.4 5.2 GO:1990226 histone methyltransferase binding(GO:1990226)
0.4 26.6 GO:0003697 single-stranded DNA binding(GO:0003697)
0.4 2.2 GO:0004983 neuropeptide Y receptor activity(GO:0004983)
0.4 11.5 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.4 8.5 GO:0032794 GTPase activating protein binding(GO:0032794)
0.3 2.8 GO:1990446 U1 snRNP binding(GO:1990446)
0.3 13.8 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.3 3.8 GO:0102338 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.3 2.3 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.3 4.6 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.3 6.2 GO:0070402 NADPH binding(GO:0070402)
0.3 2.6 GO:0070739 protein-glutamic acid ligase activity(GO:0070739)
0.3 2.2 GO:0042289 MHC class II protein binding(GO:0042289)
0.3 1.2 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.3 2.5 GO:0005237 inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.3 1.8 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.3 17.2 GO:0043425 bHLH transcription factor binding(GO:0043425)
0.3 2.6 GO:0034711 inhibin binding(GO:0034711)
0.3 1.2 GO:0004897 ciliary neurotrophic factor receptor activity(GO:0004897)
0.3 0.9 GO:0052740 phosphatidylserine 1-acylhydrolase activity(GO:0052739) 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.3 1.4 GO:1990188 euchromatin binding(GO:1990188)
0.3 2.2 GO:0003993 acid phosphatase activity(GO:0003993)
0.3 1.1 GO:0031800 type 3 metabotropic glutamate receptor binding(GO:0031800)
0.3 2.1 GO:0043237 laminin-1 binding(GO:0043237)
0.3 1.6 GO:0042296 ISG15 transferase activity(GO:0042296)
0.3 36.9 GO:0004386 helicase activity(GO:0004386)
0.3 1.5 GO:0097016 L27 domain binding(GO:0097016)
0.3 3.9 GO:0048406 nerve growth factor binding(GO:0048406)
0.3 7.7 GO:0070888 E-box binding(GO:0070888)
0.3 6.5 GO:0008432 JUN kinase binding(GO:0008432)
0.2 8.0 GO:0017025 TBP-class protein binding(GO:0017025)
0.2 0.5 GO:0036033 mediator complex binding(GO:0036033)
0.2 2.9 GO:0016868 intramolecular transferase activity, phosphotransferases(GO:0016868)
0.2 10.1 GO:0031369 translation initiation factor binding(GO:0031369)
0.2 4.5 GO:0001056 RNA polymerase III activity(GO:0001056)
0.2 9.6 GO:0003743 translation initiation factor activity(GO:0003743)
0.2 1.6 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.2 0.7 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.2 1.9 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.2 10.7 GO:0070063 RNA polymerase binding(GO:0070063)
0.2 1.8 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.2 1.3 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.2 1.5 GO:0045545 syndecan binding(GO:0045545)
0.2 3.1 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.2 1.0 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.2 46.3 GO:0001047 core promoter binding(GO:0001047)
0.2 34.4 GO:0003735 structural constituent of ribosome(GO:0003735)
0.2 0.8 GO:0032296 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.2 3.7 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds(GO:0016799)
0.2 1.7 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.2 4.6 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.2 3.0 GO:0008327 methyl-CpG binding(GO:0008327)
0.2 2.6 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.2 1.5 GO:1901612 cardiolipin binding(GO:1901612)
0.2 7.6 GO:0003755 peptidyl-prolyl cis-trans isomerase activity(GO:0003755)
0.2 1.3 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.2 4.9 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.2 0.7 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.2 1.4 GO:0051011 microtubule minus-end binding(GO:0051011)
0.2 2.1 GO:0005522 profilin binding(GO:0005522)
0.2 14.1 GO:0031490 chromatin DNA binding(GO:0031490)
0.2 0.8 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.2 0.3 GO:0001226 RNA polymerase II transcription corepressor binding(GO:0001226)
0.2 3.0 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.2 0.3 GO:0031750 D3 dopamine receptor binding(GO:0031750)
0.2 1.0 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.2 4.7 GO:0003684 damaged DNA binding(GO:0003684)
0.2 0.8 GO:0044388 small protein activating enzyme binding(GO:0044388)
0.2 3.9 GO:0017160 Ral GTPase binding(GO:0017160)
0.2 0.9 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.2 12.8 GO:0003823 antigen binding(GO:0003823)
0.1 4.6 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.1 0.9 GO:0042285 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.1 13.2 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 22.4 GO:0042393 histone binding(GO:0042393)
0.1 2.1 GO:0043495 protein anchor(GO:0043495)
0.1 2.1 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.1 0.4 GO:0008940 nitrate reductase activity(GO:0008940)
0.1 0.7 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.1 0.7 GO:0061665 SUMO ligase activity(GO:0061665)
0.1 0.7 GO:0042979 ornithine decarboxylase regulator activity(GO:0042979)
0.1 0.8 GO:0004359 glutaminase activity(GO:0004359)
0.1 1.5 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.1 2.6 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.1 2.5 GO:0008307 structural constituent of muscle(GO:0008307)
0.1 0.7 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.1 1.2 GO:0015266 protein channel activity(GO:0015266)
0.1 0.5 GO:0003726 double-stranded RNA adenosine deaminase activity(GO:0003726)
0.1 0.6 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.1 0.8 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.1 3.2 GO:0051879 Hsp90 protein binding(GO:0051879)
0.1 0.2 GO:0016880 acid-ammonia (or amide) ligase activity(GO:0016880)
0.1 1.5 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.1 0.8 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1 0.7 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 1.6 GO:0031491 nucleosome binding(GO:0031491)
0.1 0.7 GO:0089720 caspase binding(GO:0089720)
0.1 2.7 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1 2.3 GO:0003951 NAD+ kinase activity(GO:0003951)
0.1 0.9 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1 2.4 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.1 10.0 GO:0101005 thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.1 0.5 GO:0001091 RNA polymerase II basal transcription factor binding(GO:0001091)
0.1 0.4 GO:0052798 beta-galactoside alpha-2,3-sialyltransferase activity(GO:0052798)
0.1 1.0 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.1 8.9 GO:0003777 microtubule motor activity(GO:0003777)
0.1 1.4 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.1 0.8 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.1 0.7 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.1 0.3 GO:0019153 protein-disulfide reductase (glutathione) activity(GO:0019153)
0.1 1.4 GO:0048038 quinone binding(GO:0048038)
0.1 1.1 GO:0031418 L-ascorbic acid binding(GO:0031418)
0.1 0.9 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 0.5 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.1 0.4 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.1 0.1 GO:0001727 lipid kinase activity(GO:0001727)
0.1 16.2 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.1 0.6 GO:0035014 phosphatidylinositol 3-kinase regulator activity(GO:0035014)
0.1 0.3 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.1 0.2 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
0.1 1.8 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.1 0.4 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.1 2.1 GO:0042169 SH2 domain binding(GO:0042169)
0.1 1.2 GO:0008483 transaminase activity(GO:0008483)
0.1 0.6 GO:0070034 telomerase RNA binding(GO:0070034)
0.1 1.6 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.1 1.1 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.1 7.4 GO:0004725 protein tyrosine phosphatase activity(GO:0004725)
0.1 2.0 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 1.0 GO:0017075 syntaxin-1 binding(GO:0017075)
0.1 0.7 GO:0071837 HMG box domain binding(GO:0071837)
0.1 1.1 GO:0004536 deoxyribonuclease activity(GO:0004536)
0.1 2.4 GO:0005547 phosphatidylinositol-3,4,5-trisphosphate binding(GO:0005547)
0.1 0.9 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.1 28.4 GO:0004674 protein serine/threonine kinase activity(GO:0004674)
0.0 2.1 GO:0002039 p53 binding(GO:0002039)
0.0 0.1 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.0 1.0 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 1.5 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 1.4 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.4 GO:0016717 oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water(GO:0016717)
0.0 1.9 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.4 GO:0043208 glycosphingolipid binding(GO:0043208)
0.0 0.9 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.8 GO:0016866 intramolecular transferase activity(GO:0016866)
0.0 0.4 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 0.2 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 1.2 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 0.8 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.1 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0 0.8 GO:0008373 sialyltransferase activity(GO:0008373)
0.0 0.4 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.1 GO:0008172 S-methyltransferase activity(GO:0008172)
0.0 0.1 GO:0001069 regulatory region RNA binding(GO:0001069)
0.0 0.4 GO:1990459 transferrin receptor binding(GO:1990459)
0.0 7.5 GO:0008022 protein C-terminus binding(GO:0008022)
0.0 1.2 GO:0005504 fatty acid binding(GO:0005504)
0.0 2.1 GO:0004721 phosphoprotein phosphatase activity(GO:0004721)
0.0 0.3 GO:0004331 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.0 0.6 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 0.6 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.0 0.2 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.0 1.0 GO:0019894 kinesin binding(GO:0019894)
0.0 0.9 GO:0050699 WW domain binding(GO:0050699)
0.0 0.1 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.0 0.2 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.5 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.3 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.3 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 0.5 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.3 GO:0051400 BH domain binding(GO:0051400)
0.0 0.5 GO:0008276 protein methyltransferase activity(GO:0008276)
0.0 0.1 GO:0019966 interleukin-1 binding(GO:0019966)
0.0 0.2 GO:0015114 phosphate ion transmembrane transporter activity(GO:0015114)
0.0 0.1 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.6 GO:0001104 RNA polymerase II transcription cofactor activity(GO:0001104)
0.0 0.1 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.0 0.2 GO:0004383 guanylate cyclase activity(GO:0004383)
0.0 0.4 GO:0005109 frizzled binding(GO:0005109)
0.0 0.0 GO:0043559 insulin binding(GO:0043559)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
2.4 117.6 PID ATR PATHWAY ATR signaling pathway
2.1 28.9 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
1.1 90.8 PID E2F PATHWAY E2F transcription factor network
1.1 50.7 PID AURORA B PATHWAY Aurora B signaling
1.1 1.1 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.6 16.8 PID ATM PATHWAY ATM pathway
0.5 2.2 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.5 15.7 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.5 5.3 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.4 9.7 PID FANCONI PATHWAY Fanconi anemia pathway
0.4 8.0 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.3 14.4 PID PLK1 PATHWAY PLK1 signaling events
0.3 26.1 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.2 10.9 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.2 5.7 PID TRAIL PATHWAY TRAIL signaling pathway
0.2 6.5 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.2 1.7 PID BARD1 PATHWAY BARD1 signaling events
0.2 3.7 PID FAS PATHWAY FAS (CD95) signaling pathway
0.2 3.6 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.2 3.2 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1 3.6 PID PS1 PATHWAY Presenilin action in Notch and Wnt signaling
0.1 5.9 PID TGFBR PATHWAY TGF-beta receptor signaling
0.1 2.9 PID GLYPICAN 1PATHWAY Glypican 1 network
0.1 2.9 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.1 5.1 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.1 1.2 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.1 3.6 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 3.0 PID ALK1 PATHWAY ALK1 signaling events
0.1 4.9 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.1 5.0 PID P53 REGULATION PATHWAY p53 pathway
0.1 1.6 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.1 2.5 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.1 6.2 PID AR PATHWAY Coregulation of Androgen receptor activity
0.1 1.6 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.1 4.5 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 3.4 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.1 1.9 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.1 0.9 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.1 4.5 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.1 0.8 PID CD40 PATHWAY CD40/CD40L signaling
0.1 1.8 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.1 2.2 PID ATF2 PATHWAY ATF-2 transcription factor network
0.1 1.1 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.1 1.6 PID RAS PATHWAY Regulation of Ras family activation
0.1 0.7 ST JAK STAT PATHWAY Jak-STAT Pathway
0.1 1.1 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.1 1.1 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.1 1.5 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.1 0.5 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.1 3.3 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.1 0.3 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.1 0.6 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.1 0.8 PID RHOA PATHWAY RhoA signaling pathway
0.1 1.3 PID IL6 7 PATHWAY IL6-mediated signaling events
0.1 11.4 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.1 2.4 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.1 1.1 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.1 1.8 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.1 0.7 PID IL2 1PATHWAY IL2-mediated signaling events
0.1 1.8 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.6 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.3 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 1.1 PID BCR 5PATHWAY BCR signaling pathway
0.0 1.7 PID CMYB PATHWAY C-MYB transcription factor network
0.0 0.9 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 0.7 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.0 0.6 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.0 0.5 PID IL1 PATHWAY IL1-mediated signaling events
0.0 0.7 PID CDC42 PATHWAY CDC42 signaling events
0.0 0.0 PID IGF1 PATHWAY IGF1 pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
4.9 78.0 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
2.9 54.7 REACTOME DNA STRAND ELONGATION Genes involved in DNA strand elongation
2.6 41.0 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
2.1 28.8 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
2.0 34.3 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
1.3 13.1 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
1.3 5.2 REACTOME RNA POL I TRANSCRIPTION Genes involved in RNA Polymerase I Transcription
1.2 14.3 REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX Genes involved in Activation of the pre-replicative complex
0.9 22.7 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.9 5.5 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.8 0.8 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.8 2.3 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.7 11.7 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.7 10.6 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.6 4.9 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.6 16.1 REACTOME KINESINS Genes involved in Kinesins
0.6 20.1 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.6 29.4 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.5 48.1 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.5 20.1 REACTOME G1 PHASE Genes involved in G1 Phase
0.5 5.2 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.5 11.7 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.5 22.3 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS Genes involved in CREB phosphorylation through the activation of Ras
0.5 3.6 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.4 4.9 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.4 17.4 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.4 8.9 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.4 6.8 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.4 13.4 REACTOME FATTY ACYL COA BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis
0.4 5.3 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.3 5.3 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.3 2.6 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.3 5.1 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.3 5.8 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.3 5.4 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.3 5.3 REACTOME NUCLEAR EVENTS KINASE AND TRANSCRIPTION FACTOR ACTIVATION Genes involved in Nuclear Events (kinase and transcription factor activation)
0.3 5.6 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.2 0.5 REACTOME ABORTIVE ELONGATION OF HIV1 TRANSCRIPT IN THE ABSENCE OF TAT Genes involved in Abortive elongation of HIV-1 transcript in the absence of Tat
0.2 4.0 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.2 4.5 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.2 13.8 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes
0.2 5.1 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.2 0.4 REACTOME ARMS MEDIATED ACTIVATION Genes involved in ARMS-mediated activation
0.2 3.6 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.2 5.4 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.2 2.9 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.2 1.3 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.2 3.4 REACTOME DOWNREGULATION OF TGF BETA RECEPTOR SIGNALING Genes involved in Downregulation of TGF-beta receptor signaling
0.2 1.9 REACTOME RESOLUTION OF AP SITES VIA THE MULTIPLE NUCLEOTIDE PATCH REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the multiple-nucleotide patch replacement pathway
0.2 4.0 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.2 4.9 REACTOME MYOGENESIS Genes involved in Myogenesis
0.2 4.6 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.2 2.8 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.2 2.3 REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A Genes involved in APC-Cdc20 mediated degradation of Nek2A
0.2 2.1 REACTOME MRNA CAPPING Genes involved in mRNA Capping
0.1 0.9 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.1 2.8 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.1 1.4 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.1 0.1 REACTOME INCRETIN SYNTHESIS SECRETION AND INACTIVATION Genes involved in Incretin Synthesis, Secretion, and Inactivation
0.1 7.4 REACTOME APOPTOTIC CLEAVAGE OF CELLULAR PROTEINS Genes involved in Apoptotic cleavage of cellular proteins
0.1 9.0 REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
0.1 1.0 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.1 2.3 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.1 0.7 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.1 0.8 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.1 1.1 REACTOME FORMATION OF RNA POL II ELONGATION COMPLEX Genes involved in Formation of RNA Pol II elongation complex
0.1 2.1 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.1 1.5 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1 7.6 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.1 0.3 REACTOME RNA POL I TRANSCRIPTION INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.1 1.2 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.1 23.2 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.1 1.9 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.1 1.8 REACTOME TRANSCRIPTION Genes involved in Transcription
0.1 0.6 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.1 3.3 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.1 4.6 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.1 1.4 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.1 0.6 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.1 1.1 REACTOME LATE PHASE OF HIV LIFE CYCLE Genes involved in Late Phase of HIV Life Cycle
0.1 2.5 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 2.7 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.1 3.5 REACTOME DNA REPAIR Genes involved in DNA Repair
0.1 2.5 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.1 1.8 REACTOME HOST INTERACTIONS OF HIV FACTORS Genes involved in Host Interactions of HIV factors
0.1 5.9 REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
0.1 0.8 REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES Genes involved in p75NTR recruits signalling complexes
0.1 2.6 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.1 1.4 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.1 1.5 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.1 0.9 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.1 4.0 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.1 1.3 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.1 1.9 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.1 0.4 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.1 1.3 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.5 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.0 0.9 REACTOME GENERIC TRANSCRIPTION PATHWAY Genes involved in Generic Transcription Pathway
0.0 0.2 REACTOME INWARDLY RECTIFYING K CHANNELS Genes involved in Inwardly rectifying K+ channels
0.0 0.5 REACTOME MRNA PROCESSING Genes involved in mRNA Processing
0.0 1.0 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.7 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.5 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0 1.5 REACTOME ION CHANNEL TRANSPORT Genes involved in Ion channel transport
0.0 0.6 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 0.7 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 1.2 REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.0 0.8 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.8 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0 0.6 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.7 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.7 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.0 0.6 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.0 0.3 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.0 0.6 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 0.9 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.1 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 0.5 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 0.1 REACTOME MITOTIC G1 G1 S PHASES Genes involved in Mitotic G1-G1/S phases
0.0 0.2 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors