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2D miR_HR1_12

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Results for Pparg_Rxrg

Z-value: 0.87

Motif logo

Transcription factors associated with Pparg_Rxrg

Gene Symbol Gene ID Gene Info
ENSMUSG00000000440.6 peroxisome proliferator activated receptor gamma
ENSMUSG00000015843.4 retinoid X receptor gamma

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Ppargmm10_v2_chr6_+_115361221_115361280-0.537.8e-02Click!
Rxrgmm10_v2_chr1_+_167598384_1675984110.441.5e-01Click!

Activity profile of Pparg_Rxrg motif

Sorted Z-values of Pparg_Rxrg motif

Promoter Log-likelihood Transcript Gene Gene Info
chr7_+_30493622 2.96 ENSMUST00000058280.6
ENSMUST00000133318.1
ENSMUST00000142575.1
ENSMUST00000131040.1
proline dehydrogenase (oxidase) 2
chr16_-_19200350 1.50 ENSMUST00000103749.2
immunoglobulin lambda constant 2
chr17_-_48167187 1.38 ENSMUST00000053612.6
ENSMUST00000027764.8
RIKEN cDNA A530064D06 gene
chr11_-_83592981 1.15 ENSMUST00000019071.3
chemokine (C-C motif) ligand 6
chr11_-_77894096 1.13 ENSMUST00000017597.4
pipecolic acid oxidase
chr9_-_46235631 1.01 ENSMUST00000118649.1
apolipoprotein C-III
chr8_+_13026024 0.94 ENSMUST00000033820.3
coagulation factor VII
chr16_+_23146536 0.88 ENSMUST00000023593.5
ENSMUST00000171309.1
adiponectin, C1Q and collagen domain containing
chr8_-_72009619 0.83 ENSMUST00000003574.4
cytochrome P450, family 4, subfamily f, polypeptide 18
chr4_+_132564051 0.67 ENSMUST00000070690.7
platelet-activating factor receptor
chr3_-_130061553 0.67 ENSMUST00000168675.1
Sec24 related gene family, member B (S. cerevisiae)
chr17_+_48316141 0.67 ENSMUST00000049614.6
RIKEN cDNA B430306N03 gene
chr17_+_48299952 0.67 ENSMUST00000170941.1
triggering receptor expressed on myeloid cells-like 2
chr16_+_5007283 0.65 ENSMUST00000184439.1
small integral membrane protein 22
chr7_-_43660139 0.60 ENSMUST00000032667.8
sialic acid binding Ig-like lectin E
chr2_+_144033059 0.52 ENSMUST00000037722.2
ENSMUST00000110032.1
barrier to autointegration factor 2
chr7_+_140835018 0.43 ENSMUST00000106050.1
ENSMUST00000026554.4
urate (5-hydroxyiso-) hydrolase
chr1_+_172555932 0.42 ENSMUST00000061835.3
V-set and immunoglobulin domain containing 8
chr12_-_113422730 0.42 ENSMUST00000177715.1
ENSMUST00000103426.1
immunoglobulin heavy constant mu
chr19_-_6921753 0.42 ENSMUST00000173635.1
estrogen related receptor, alpha
chr11_+_78920787 0.41 ENSMUST00000018610.6
nitric oxide synthase 2, inducible
chr11_+_46404720 0.39 ENSMUST00000063166.5
family with sequence similarity 71, member B
chr7_+_43437073 0.39 ENSMUST00000070518.2
natural killer cell group 7 sequence
chr7_-_3845050 0.37 ENSMUST00000108615.3
ENSMUST00000119469.1
paired-Ig-like receptor A2
chr6_-_123289862 0.36 ENSMUST00000032239.4
ENSMUST00000177367.1
C-type lectin domain family 4, member e
chr5_-_88527841 0.36 ENSMUST00000087033.3
immunoglobulin joining chain
chr4_+_150148905 0.35 ENSMUST00000059893.7
solute carrier family 2 (facilitated glucose transporter), member 7
chr2_+_160888101 0.35 ENSMUST00000109455.2
ENSMUST00000040872.6
lipin 3
chr2_+_24336846 0.34 ENSMUST00000114487.2
interleukin 1 receptor antagonist
chr5_-_17835857 0.33 ENSMUST00000082367.6
CD36 antigen
chr7_+_55768184 0.33 ENSMUST00000121492.1
ENSMUST00000171077.1
ENSMUST00000060416.8
ENSMUST00000094360.6
ENSMUST00000165045.2
ENSMUST00000173835.1
sialic acid binding Ig-like lectin H
chr2_+_91096744 0.32 ENSMUST00000132741.2
spleen focus forming virus (SFFV) proviral integration oncogene
chr19_+_11516473 0.32 ENSMUST00000163078.1
membrane-spanning 4-domains, subfamily A, member 6B
chr9_-_22135675 0.32 ENSMUST00000165735.1
acid phosphatase 5, tartrate resistant
chr19_+_10001669 0.31 ENSMUST00000121418.1
RAB3A interacting protein (rabin3)-like 1
chr9_-_106476104 0.31 ENSMUST00000156426.1
poly (ADP-ribose) polymerase family, member 3
chr15_+_78926720 0.31 ENSMUST00000089377.5
lectin, galactose binding, soluble 1
chr19_+_11536769 0.31 ENSMUST00000025581.6
membrane-spanning 4-domains, subfamily A, member 4D
chr17_+_32621319 0.31 ENSMUST00000077639.5
predicted gene 9705
chr1_+_171113918 0.31 ENSMUST00000129651.1
ENSMUST00000151340.1
RIKEN cDNA 1700009P17 gene
chr11_+_5861886 0.30 ENSMUST00000102923.3
AE binding protein 1
chr16_+_92612755 0.30 ENSMUST00000180989.1
predicted gene, 26626
chr10_+_87859062 0.30 ENSMUST00000095360.4
insulin-like growth factor 1
chr17_-_56290499 0.29 ENSMUST00000019726.6
perilipin 3
chr3_-_103737995 0.29 ENSMUST00000029440.8
olfactomedin-like 3
chr11_-_83578496 0.29 ENSMUST00000019266.5
chemokine (C-C motif) ligand 9
chr7_-_105600103 0.29 ENSMUST00000033185.8
hemopexin
chr10_+_87058043 0.29 ENSMUST00000169849.1
RIKEN cDNA 1700113H08 gene
chr2_+_160888156 0.29 ENSMUST00000109457.2
lipin 3
chr1_+_171388954 0.28 ENSMUST00000056449.8
Rho GTPase activating protein 30
chr16_+_5007306 0.28 ENSMUST00000178155.2
ENSMUST00000184256.1
ENSMUST00000185147.1
small integral membrane protein 22
chr14_+_75136326 0.28 ENSMUST00000145303.1
lymphocyte cytosolic protein 1
chr5_-_21424664 0.28 ENSMUST00000115245.1
ENSMUST00000030552.5
coiled-coil domain containing 146
chr10_+_77530252 0.28 ENSMUST00000000299.7
ENSMUST00000131023.1
ENSMUST00000130059.1
integrin beta 2
chr4_+_42158092 0.28 ENSMUST00000098122.2
predicted gene 13306
chr13_-_95444827 0.28 ENSMUST00000045583.7
corticotropin releasing hormone binding protein
chr7_+_4925802 0.28 ENSMUST00000057612.7
scavenger receptor cysteine rich domain containing (5 domains)
chr10_+_128790903 0.27 ENSMUST00000026411.6
matrix metallopeptidase 19
chr4_+_41569775 0.27 ENSMUST00000102963.3
dynein, axonemal, intermediate chain 1
chr16_-_45158453 0.27 ENSMUST00000181750.1
solute carrier family 35, member A5
chr17_-_73950172 0.27 ENSMUST00000024866.4
xanthine dehydrogenase
chr9_-_110989611 0.27 ENSMUST00000084922.5
receptor transporter protein 3
chr2_-_180104463 0.27 ENSMUST00000056480.3
histamine receptor H3
chr13_+_91741507 0.26 ENSMUST00000022120.4
acyl-CoA thioesterase 12
chr1_-_170589791 0.26 ENSMUST00000161966.1
ENSMUST00000160456.1
nitric oxide synthase 1 (neuronal) adaptor protein
chr9_-_106476590 0.26 ENSMUST00000112479.2
poly (ADP-ribose) polymerase family, member 3
chr8_+_13037308 0.26 ENSMUST00000063820.5
ENSMUST00000033821.4
coagulation factor X
chr11_-_121039400 0.26 ENSMUST00000026159.5
CD7 antigen
chr3_+_27154020 0.26 ENSMUST00000181124.1
RIKEN cDNA 1700125G22 gene
chr2_+_91082362 0.26 ENSMUST00000169852.1
spleen focus forming virus (SFFV) proviral integration oncogene
chr2_-_32775330 0.25 ENSMUST00000161089.1
ENSMUST00000066478.2
ENSMUST00000161950.1
tetratricopeptide repeat domain 16
chr4_-_134254076 0.25 ENSMUST00000060050.5
glycine/arginine rich protein 1
chr3_-_95142346 0.25 ENSMUST00000013851.3
tumor necrosis factor, alpha-induced protein 8-like 2
chr2_-_164356507 0.25 ENSMUST00000109367.3
secretory leukocyte peptidase inhibitor
chr4_+_110397764 0.25 ENSMUST00000097920.2
ENSMUST00000080744.6
ATP/GTP binding protein-like 4
chr3_+_51661167 0.25 ENSMUST00000099106.3
microsomal glutathione S-transferase 2
chr5_-_137611372 0.25 ENSMUST00000054564.6
procollagen C-endopeptidase enhancer protein
chr17_-_23844155 0.25 ENSMUST00000122936.1
ENSMUST00000024926.7
ENSMUST00000151797.1
protease, serine, 41
chr14_-_37110087 0.25 ENSMUST00000179488.1
RIKEN cDNA 2610528A11 gene
chr19_-_40187277 0.24 ENSMUST00000051846.6
cytochrome P450, family 2, subfamily c, polypeptide 70
chr10_+_80150448 0.24 ENSMUST00000153477.1
midnolin
chr10_+_128267997 0.24 ENSMUST00000050901.2
apolipoprotein F
chr10_+_79890853 0.24 ENSMUST00000061653.7
complement factor D (adipsin)
chr5_-_113830422 0.24 ENSMUST00000100874.4
selectin, platelet (p-selectin) ligand
chr4_+_156215920 0.24 ENSMUST00000105572.1
RIKEN cDNA 2310042D19 gene
chr4_+_88803254 0.24 ENSMUST00000179490.1
predicted gene 13287
chr5_+_110514885 0.24 ENSMUST00000141532.1
RIKEN cDNA A630023P12 gene
chr1_-_87573825 0.24 ENSMUST00000068681.5
neuronal guanine nucleotide exchange factor
chr5_-_115119277 0.23 ENSMUST00000031524.7
acyl-Coenzyme A dehydrogenase, short chain
chr2_-_32775584 0.23 ENSMUST00000161430.1
tetratricopeptide repeat domain 16
chr6_+_78380700 0.23 ENSMUST00000101272.1
regenerating islet-derived 3 alpha
chr2_+_32608704 0.23 ENSMUST00000129165.1
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
chr15_-_55906722 0.23 ENSMUST00000110200.2
syntrophin, basic 1
chr5_+_120476522 0.22 ENSMUST00000066540.7
serine dehydratase
chr15_+_77698889 0.22 ENSMUST00000096358.4
apolipoprotein L 7e
chr13_+_37345338 0.22 ENSMUST00000021860.5
lymphocyte antigen 86
chr9_-_103288224 0.22 ENSMUST00000123530.1
RIKEN cDNA 1300017J02 gene
chr6_+_134414423 0.22 ENSMUST00000111960.1
BCL2-like 14 (apoptosis facilitator)
chr15_-_74752963 0.22 ENSMUST00000023259.8
Ly6/neurotoxin 1
chrX_+_101449078 0.21 ENSMUST00000033674.5
integrin beta 1 binding protein 2
chr9_+_57148180 0.21 ENSMUST00000105102.2
predicted gene 16493
chr5_-_66004278 0.21 ENSMUST00000067737.5
RIKEN cDNA 9130230L23 gene
chr2_-_38287347 0.21 ENSMUST00000102787.3
DENN/MADD domain containing 1A
chr9_+_46012810 0.21 ENSMUST00000126865.1
SIK family kinase 3
chr2_+_151999886 0.21 ENSMUST00000109858.1
solute carrier protein family 52, member 3
chr9_-_58159201 0.21 ENSMUST00000041477.7
immunoglobulin superfamily containing leucine-rich repeat
chr14_+_15437623 0.21 ENSMUST00000181388.1
RIKEN cDNA B230110C06 gene
chr13_-_62858364 0.21 ENSMUST00000021907.7
fructose bisphosphatase 2
chr2_+_152962485 0.21 ENSMUST00000099197.2
ENSMUST00000103155.3
tubulin tyrosine ligase-like family, member 9
chr2_+_151996505 0.20 ENSMUST00000109859.2
ENSMUST00000073228.5
solute carrier protein family 52, member 3
chr5_-_137611429 0.20 ENSMUST00000031731.7
procollagen C-endopeptidase enhancer protein
chr7_+_28441026 0.20 ENSMUST00000135686.1
glia maturation factor, gamma
chr3_+_107877227 0.20 ENSMUST00000037375.8
EPS8-like 3
chr1_-_180195981 0.20 ENSMUST00000027766.6
ENSMUST00000161814.1
aarF domain containing kinase 3
chr4_+_88776922 0.20 ENSMUST00000179158.1
predicted gene 13289
chr15_-_77447444 0.20 ENSMUST00000089469.5
apolipoprotein L 7b
chr9_-_103288290 0.20 ENSMUST00000035163.3
RIKEN cDNA 1300017J02 gene
chr11_+_59541568 0.19 ENSMUST00000079476.3
NLR family, pyrin domain containing 3
chr10_-_80261004 0.19 ENSMUST00000105363.1
guanidinoacetate methyltransferase
chr2_+_151999865 0.19 ENSMUST00000109861.1
solute carrier protein family 52, member 3
chr2_-_28563362 0.19 ENSMUST00000028161.5
carboxyl ester lipase
chr19_-_6921804 0.19 ENSMUST00000025906.4
estrogen related receptor, alpha
chr9_+_21015960 0.19 ENSMUST00000086399.4
intercellular adhesion molecule 1
chr11_+_98836775 0.19 ENSMUST00000107479.2
Rap guanine nucleotide exchange factor (GEF)-like 1
chrX_+_20870166 0.19 ENSMUST00000115342.3
ENSMUST00000009530.4
tissue inhibitor of metalloproteinase 1
chr7_-_100964371 0.19 ENSMUST00000060174.4
pyrimidinergic receptor P2Y, G-protein coupled, 6
chr2_+_25080316 0.18 ENSMUST00000044078.3
ENSMUST00000114380.2
ectonucleoside triphosphate diphosphohydrolase 8
chr16_+_33794008 0.18 ENSMUST00000115044.1
mucin 13, epithelial transmembrane
chr19_-_10001625 0.18 ENSMUST00000117346.1
bestrophin 1
chr11_+_120608469 0.18 ENSMUST00000106194.1
ENSMUST00000106195.2
neuropeptide B
chr17_-_31129602 0.18 ENSMUST00000024827.4
trefoil factor 3, intestinal
chr9_+_108392820 0.18 ENSMUST00000035234.4
RIKEN cDNA 1700102P08 gene
chr3_-_116712696 0.18 ENSMUST00000169530.1
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member 3
chr15_-_55906917 0.18 ENSMUST00000039769.5
syntrophin, basic 1
chr16_+_33794345 0.18 ENSMUST00000023520.6
mucin 13, epithelial transmembrane
chr5_+_149006948 0.18 ENSMUST00000124198.1
predicted gene 15408
chr6_+_103510874 0.18 ENSMUST00000066905.6
cell adhesion molecule with homology to L1CAM
chr3_+_122729158 0.18 ENSMUST00000066728.5
phosphodiesterase 5A, cGMP-specific
chr4_-_131672133 0.18 ENSMUST00000144212.1
predicted gene 12962
chr10_-_80260959 0.18 ENSMUST00000020359.6
guanidinoacetate methyltransferase
chr4_+_41941572 0.18 ENSMUST00000108028.2
ENSMUST00000153997.1
predicted gene, 20878
chr7_-_67222412 0.18 ENSMUST00000181631.1
RIKEN cDNA 1700112J16 gene
chr4_-_106727930 0.17 ENSMUST00000106770.1
ENSMUST00000145044.1
maestro heat-like repeat family member 7
chr7_-_126584220 0.17 ENSMUST00000128970.1
ENSMUST00000116269.2
ceroid lipofuscinosis, neuronal 3, juvenile (Batten, Spielmeyer-Vogt disease)
chr1_+_74409376 0.17 ENSMUST00000027366.6
villin 1
chr11_+_96931387 0.17 ENSMUST00000107633.1
proline rich 15-like
chr4_+_138725282 0.17 ENSMUST00000030530.4
ENSMUST00000124660.1
phospholipase A2, group IIC
chr19_-_7607103 0.17 ENSMUST00000079902.5
ENSMUST00000099729.3
ENSMUST00000159983.1
lectin, galactose binding, soluble 12
chr1_+_133309778 0.17 ENSMUST00000094557.4
ENSMUST00000183457.1
ENSMUST00000183738.1
ENSMUST00000185157.1
ENSMUST00000184603.1
golgi transport 1 homolog A (S. cerevisiae)
KiSS-1 metastasis-suppressor
KISS1 isoform e
chr7_+_4337710 0.17 ENSMUST00000006792.4
natural cytotoxicity triggering receptor 1
chr4_+_88754868 0.17 ENSMUST00000094992.1
predicted gene 13271
chr6_+_83156401 0.17 ENSMUST00000032106.4
RIKEN cDNA 1700003E16 gene
chr7_+_46841475 0.17 ENSMUST00000147535.1
lactate dehydrogenase A
chr15_+_100353149 0.17 ENSMUST00000075675.5
ENSMUST00000088142.5
ENSMUST00000176287.1
cDNA sequence AB099516
methyltransferase like 7A2
chr5_+_122210134 0.17 ENSMUST00000100747.2
hydrogen voltage-gated channel 1
chr8_+_71469186 0.17 ENSMUST00000124745.1
ENSMUST00000138892.1
ENSMUST00000147642.1
DET1 and DDB1 associated 1
chr14_+_75136475 0.17 ENSMUST00000122840.1
lymphocyte cytosolic protein 1
chr15_-_77533312 0.17 ENSMUST00000062562.5
apolipoprotein L 7c
chr5_-_70842617 0.17 ENSMUST00000031119.1
gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1
chr18_+_65698253 0.17 ENSMUST00000115097.1
ENSMUST00000117694.1
O-acyltransferase like
chr5_+_114146525 0.17 ENSMUST00000102582.1
acetyl-Coenzyme A carboxylase beta
chr4_-_140845770 0.17 ENSMUST00000026378.3
peptidyl arginine deiminase, type I
chr11_-_78386558 0.17 ENSMUST00000108294.1
forkhead box N1
chr8_+_71568866 0.17 ENSMUST00000034267.4
solute carrier family 27 (fatty acid transporter), member 1
chr15_+_100423193 0.17 ENSMUST00000148928.1
predicted gene 5475
chr17_-_34882004 0.17 ENSMUST00000152417.1
ENSMUST00000146299.1
complement component 2 (within H-2S)
predicted gene 20547
chr9_+_50752758 0.16 ENSMUST00000034562.7
crystallin, alpha B
chr18_-_36726730 0.16 ENSMUST00000061829.6
CD14 antigen
chr10_-_81183849 0.16 ENSMUST00000056086.4
RIKEN cDNA 4930442H23 gene
chr7_-_52015710 0.16 ENSMUST00000180038.1
RIKEN cDNA 1700015G11 gene
chr19_+_45998131 0.16 ENSMUST00000181820.1
RIKEN cDNA 4930505N22 gene
chr3_-_79628660 0.16 ENSMUST00000120992.1
electron transferring flavoprotein, dehydrogenase
chr5_+_3845171 0.16 ENSMUST00000044039.1
ENSMUST00000143027.1
leucine rich repeats and death domain containing 1
chr8_+_13037802 0.16 ENSMUST00000152034.1
ENSMUST00000128418.1
coagulation factor X
chr11_-_49114874 0.16 ENSMUST00000109201.1
olfactory receptor 1396
chr5_-_105239533 0.16 ENSMUST00000065588.6
guanylate-binding protein 10
chr1_-_171234290 0.16 ENSMUST00000079957.6
Fc receptor, IgE, high affinity I, gamma polypeptide
chr15_-_84123174 0.16 ENSMUST00000019012.3
patatin-like phospholipase domain containing 5
chr5_+_122209729 0.16 ENSMUST00000072602.7
ENSMUST00000143560.1
hydrogen voltage-gated channel 1
chr16_+_29209695 0.16 ENSMUST00000089824.4
HRAS-like suppressor
chr1_-_171059390 0.16 ENSMUST00000164044.1
ENSMUST00000169017.1
Fc receptor, IgG, low affinity III
chr19_+_4081565 0.15 ENSMUST00000159593.1
calcium binding protein 2
chrX_-_7928607 0.15 ENSMUST00000033500.4
ES cell-expressed Ras
chr2_-_154603698 0.15 ENSMUST00000000896.4
peroxisomal membrane protein 4
chr5_-_107723954 0.15 ENSMUST00000165344.1
growth factor independent 1
chr11_+_103116228 0.15 ENSMUST00000053063.5
hexamethylene bis-acetamide inducible 1
chr7_-_19950729 0.15 ENSMUST00000043440.6
immunoglobulin superfamily, member 23
chr7_-_27985796 0.15 ENSMUST00000099111.3
zinc finger protein 850
chr5_+_64970069 0.15 ENSMUST00000031080.8
family with sequence similarity 114, member A1
chr11_-_103356324 0.15 ENSMUST00000136491.2
ENSMUST00000107023.2
Rho GTPase activating protein 27
chr3_+_116513070 0.15 ENSMUST00000000349.6
dihydrolipoamide branched chain transacylase E2
chr3_-_102936093 0.15 ENSMUST00000029448.6
synaptonemal complex protein 1
chrX_-_106603677 0.15 ENSMUST00000113480.1
cysteinyl leukotriene receptor 1
chr11_-_34783850 0.15 ENSMUST00000093193.5
ENSMUST00000101365.2
dedicator of cyto-kinesis 2
chr11_+_115475645 0.15 ENSMUST00000035240.6
armadillo repeat containing 7
chr11_-_3504766 0.15 ENSMUST00000044507.5
inositol polyphosphate 5-phosphatase J
chr10_+_75571522 0.15 ENSMUST00000143226.1
ENSMUST00000124259.1
gamma-glutamyltransferase 1
chr2_-_103303179 0.15 ENSMUST00000090475.3
ets homologous factor
chr9_+_106499967 0.15 ENSMUST00000164965.1
ENSMUST00000085114.5
IQ motif containing F1
chr17_+_86963279 0.14 ENSMUST00000139344.1
ras homolog gene family, member Q

Network of associatons between targets according to the STRING database.

First level regulatory network of Pparg_Rxrg

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.0 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.4 1.1 GO:0006553 lysine metabolic process(GO:0006553)
0.3 0.9 GO:0072244 metanephric glomerular epithelium development(GO:0072244)
0.3 0.8 GO:0042374 phylloquinone metabolic process(GO:0042374) phylloquinone catabolic process(GO:0042376) quinone catabolic process(GO:1901662)
0.2 0.7 GO:1990166 protein localization to site of double-strand break(GO:1990166)
0.2 0.9 GO:0010641 positive regulation of platelet-derived growth factor receptor signaling pathway(GO:0010641)
0.2 0.7 GO:1902943 regulation of voltage-gated chloride channel activity(GO:1902941) positive regulation of voltage-gated chloride channel activity(GO:1902943)
0.2 0.8 GO:0010982 regulation of high-density lipoprotein particle clearance(GO:0010982)
0.2 0.7 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.2 0.2 GO:0071725 response to triacyl bacterial lipopeptide(GO:0071725) cellular response to triacyl bacterial lipopeptide(GO:0071727)
0.2 0.6 GO:1905154 negative regulation of membrane invagination(GO:1905154)
0.1 0.6 GO:0032218 riboflavin transport(GO:0032218)
0.1 0.4 GO:0002344 peripheral B cell selection(GO:0002343) B cell affinity maturation(GO:0002344)
0.1 0.4 GO:0006601 creatine biosynthetic process(GO:0006601)
0.1 0.6 GO:0045347 negative regulation of MHC class II biosynthetic process(GO:0045347)
0.1 0.3 GO:0070543 response to linoleic acid(GO:0070543)
0.1 0.3 GO:0001805 type III hypersensitivity(GO:0001802) regulation of type III hypersensitivity(GO:0001803) positive regulation of type III hypersensitivity(GO:0001805)
0.1 0.3 GO:0090341 negative regulation of secretion of lysosomal enzymes(GO:0090341)
0.1 0.3 GO:0071314 cellular response to cocaine(GO:0071314)
0.1 0.4 GO:0030321 transepithelial chloride transport(GO:0030321)
0.1 0.4 GO:0038094 Fc-gamma receptor signaling pathway(GO:0038094)
0.1 0.4 GO:0035609 C-terminal protein deglutamylation(GO:0035609)
0.1 0.3 GO:0042494 detection of bacterial lipoprotein(GO:0042494)
0.1 0.2 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
0.1 0.3 GO:0015886 heme transport(GO:0015886)
0.1 0.2 GO:2000170 positive regulation of peptidyl-cysteine S-nitrosylation(GO:2000170)
0.1 0.3 GO:0009115 xanthine catabolic process(GO:0009115)
0.1 0.2 GO:0046351 disaccharide biosynthetic process(GO:0046351)
0.1 0.3 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.1 0.4 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.1 0.2 GO:0071846 actin filament debranching(GO:0071846)
0.1 0.1 GO:0006145 purine nucleobase catabolic process(GO:0006145)
0.1 0.2 GO:0002678 positive regulation of chronic inflammatory response(GO:0002678)
0.1 0.6 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
0.1 0.1 GO:1900239 phenotypic switching(GO:0036166) regulation of phenotypic switching(GO:1900239)
0.1 0.2 GO:0046949 fatty-acyl-CoA biosynthetic process(GO:0046949) malonyl-CoA metabolic process(GO:2001293)
0.1 1.5 GO:0006910 phagocytosis, recognition(GO:0006910)
0.1 0.2 GO:0036414 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.1 0.2 GO:0097535 lymphoid lineage cell migration(GO:0097534) lymphoid lineage cell migration into thymus(GO:0097535)
0.1 0.2 GO:1900533 medium-chain fatty-acyl-CoA catabolic process(GO:0036114) fatty-acyl-CoA catabolic process(GO:0036115) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
0.1 0.3 GO:0014063 negative regulation of serotonin secretion(GO:0014063)
0.1 0.3 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.1 0.3 GO:1904073 regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
0.0 0.1 GO:0000711 meiotic DNA repair synthesis(GO:0000711)
0.0 0.1 GO:0002277 myeloid dendritic cell activation involved in immune response(GO:0002277)
0.0 0.2 GO:2000321 positive regulation of T-helper 17 cell differentiation(GO:2000321)
0.0 0.1 GO:0030450 regulation of complement activation, classical pathway(GO:0030450)
0.0 0.2 GO:1902896 terminal web assembly(GO:1902896)
0.0 0.1 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.0 0.2 GO:0032278 positive regulation of gonadotropin secretion(GO:0032278)
0.0 0.1 GO:0071718 sodium-independent icosanoid transport(GO:0071718)
0.0 0.3 GO:0002159 desmosome assembly(GO:0002159)
0.0 0.2 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659) negative regulation of phospholipid biosynthetic process(GO:0071072)
0.0 0.1 GO:0035938 estradiol secretion(GO:0035938) regulation of estradiol secretion(GO:2000864)
0.0 0.1 GO:0036118 hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.0 0.1 GO:0046370 fructose biosynthetic process(GO:0046370)
0.0 0.2 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
0.0 0.5 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.7 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 0.1 GO:0006842 tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
0.0 0.1 GO:0071929 alpha-tubulin acetylation(GO:0071929)
0.0 0.1 GO:1902093 positive regulation of sperm motility(GO:1902093)
0.0 0.0 GO:0061350 planar cell polarity pathway involved in outflow tract morphogenesis(GO:0061347) planar cell polarity pathway involved in ventricular septum morphogenesis(GO:0061348) planar cell polarity pathway involved in cardiac right atrium morphogenesis(GO:0061349) planar cell polarity pathway involved in cardiac muscle tissue morphogenesis(GO:0061350) planar cell polarity pathway involved in pericardium morphogenesis(GO:0061354)
0.0 0.1 GO:0071707 immunoglobulin heavy chain V-D-J recombination(GO:0071707)
0.0 0.1 GO:2001287 negative regulation of caveolin-mediated endocytosis(GO:2001287)
0.0 0.1 GO:0060775 mediolateral intercalation(GO:0060031) planar cell polarity pathway involved in gastrula mediolateral intercalation(GO:0060775)
0.0 0.1 GO:0071918 urea transmembrane transport(GO:0071918)
0.0 0.1 GO:0071677 positive regulation of mononuclear cell migration(GO:0071677)
0.0 0.1 GO:1900060 negative regulation of ceramide biosynthetic process(GO:1900060)
0.0 0.2 GO:0009597 detection of virus(GO:0009597)
0.0 0.2 GO:0019244 lactate biosynthetic process from pyruvate(GO:0019244)
0.0 0.1 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.0 0.3 GO:0071294 cellular response to zinc ion(GO:0071294)
0.0 0.1 GO:0002730 regulation of dendritic cell cytokine production(GO:0002730)
0.0 0.1 GO:1901492 positive regulation of lymphangiogenesis(GO:1901492)
0.0 0.1 GO:0031296 B cell costimulation(GO:0031296)
0.0 0.1 GO:0002023 reduction of food intake in response to dietary excess(GO:0002023)
0.0 0.2 GO:1904996 positive regulation of leukocyte adhesion to vascular endothelial cell(GO:1904996)
0.0 0.2 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.0 0.2 GO:0010956 negative regulation of calcidiol 1-monooxygenase activity(GO:0010956) regulation of interleukin-6-mediated signaling pathway(GO:0070103)
0.0 0.2 GO:1901750 leukotriene D4 metabolic process(GO:1901748) leukotriene D4 biosynthetic process(GO:1901750)
0.0 0.1 GO:0034441 plasma lipoprotein particle oxidation(GO:0034441)
0.0 0.1 GO:2000049 positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
0.0 0.1 GO:0097089 methyl-branched fatty acid metabolic process(GO:0097089)
0.0 0.1 GO:0006562 proline catabolic process(GO:0006562)
0.0 0.1 GO:0032277 negative regulation of gonadotropin secretion(GO:0032277) negative regulation of follicle-stimulating hormone secretion(GO:0046882)
0.0 0.3 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.0 0.1 GO:0033762 response to glucagon(GO:0033762)
0.0 0.1 GO:0071963 establishment or maintenance of cell polarity regulating cell shape(GO:0071963)
0.0 0.2 GO:0031666 positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.0 0.3 GO:0061002 negative regulation of dendritic spine morphogenesis(GO:0061002)
0.0 0.1 GO:0071613 granzyme B production(GO:0071613) regulation of granzyme B production(GO:0071661) positive regulation of granzyme B production(GO:0071663)
0.0 0.1 GO:0010916 regulation of very-low-density lipoprotein particle clearance(GO:0010915) negative regulation of very-low-density lipoprotein particle clearance(GO:0010916)
0.0 1.5 GO:0002548 monocyte chemotaxis(GO:0002548)
0.0 0.2 GO:0070447 positive regulation of oligodendrocyte progenitor proliferation(GO:0070447)
0.0 0.2 GO:1903300 negative regulation of glucokinase activity(GO:0033132) negative regulation of hexokinase activity(GO:1903300)
0.0 0.1 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.0 0.1 GO:1901594 detection of temperature stimulus involved in thermoception(GO:0050960) response to capsazepine(GO:1901594)
0.0 0.1 GO:0071421 manganese ion transmembrane transport(GO:0071421)
0.0 0.1 GO:0010845 positive regulation of reciprocal meiotic recombination(GO:0010845)
0.0 0.1 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.1 GO:0007228 positive regulation of hh target transcription factor activity(GO:0007228)
0.0 0.2 GO:1901164 negative regulation of trophoblast cell migration(GO:1901164)
0.0 0.1 GO:0072592 oxygen metabolic process(GO:0072592)
0.0 0.2 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
0.0 0.1 GO:0007439 ectodermal digestive tract development(GO:0007439) embryonic ectodermal digestive tract development(GO:0048611)
0.0 0.4 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.0 0.1 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.0 0.2 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.0 GO:0044333 Wnt signaling pathway involved in digestive tract morphogenesis(GO:0044333)
0.0 0.1 GO:0000715 nucleotide-excision repair, DNA damage recognition(GO:0000715)
0.0 0.1 GO:0035964 COPI-coated vesicle budding(GO:0035964)
0.0 0.1 GO:0010624 regulation of Schwann cell proliferation(GO:0010624)
0.0 0.1 GO:0036500 ATF6-mediated unfolded protein response(GO:0036500)
0.0 0.1 GO:0015840 urea transport(GO:0015840)
0.0 0.1 GO:0034379 very-low-density lipoprotein particle assembly(GO:0034379)
0.0 0.4 GO:0097242 beta-amyloid clearance(GO:0097242)
0.0 0.5 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.1 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.0 0.1 GO:0010898 positive regulation of triglyceride catabolic process(GO:0010898)
0.0 0.3 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.1 GO:0002484 antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway(GO:0002484) antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent(GO:0002485)
0.0 0.1 GO:0032918 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.0 0.1 GO:0019355 nicotinamide nucleotide biosynthetic process from aspartate(GO:0019355) 'de novo' NAD biosynthetic process(GO:0034627) 'de novo' NAD biosynthetic process from aspartate(GO:0034628)
0.0 0.3 GO:0019370 leukotriene biosynthetic process(GO:0019370)
0.0 0.1 GO:1903797 positive regulation of inorganic anion transmembrane transport(GO:1903797)
0.0 0.1 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.0 0.1 GO:1900477 negative regulation of G1/S transition of mitotic cell cycle by negative regulation of transcription from RNA polymerase II promoter(GO:1900477)
0.0 0.1 GO:0051542 elastin biosynthetic process(GO:0051542)
0.0 0.3 GO:0050901 leukocyte tethering or rolling(GO:0050901)
0.0 0.2 GO:0043589 skin morphogenesis(GO:0043589)
0.0 0.1 GO:0032329 serine transport(GO:0032329)
0.0 0.3 GO:0006337 nucleosome disassembly(GO:0006337)
0.0 0.1 GO:0001955 blood vessel maturation(GO:0001955)
0.0 0.0 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.0 0.0 GO:2000872 positive regulation of progesterone secretion(GO:2000872)
0.0 0.1 GO:0006868 glutamine transport(GO:0006868) histidine transport(GO:0015817)
0.0 0.1 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.0 0.2 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.0 GO:0035963 response to interleukin-13(GO:0035962) cellular response to interleukin-13(GO:0035963)
0.0 0.2 GO:2000018 regulation of male gonad development(GO:2000018)
0.0 0.1 GO:1903772 regulation of viral budding via host ESCRT complex(GO:1903772)
0.0 0.1 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.1 GO:0015676 vanadium ion transport(GO:0015676) lead ion transport(GO:0015692)
0.0 0.1 GO:0015788 UDP-N-acetylglucosamine transport(GO:0015788)
0.0 0.2 GO:0009650 UV protection(GO:0009650)
0.0 0.0 GO:0072733 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.0 0.1 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.1 GO:2001268 negative regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001268)
0.0 0.0 GO:0010936 negative regulation of macrophage cytokine production(GO:0010936)
0.0 0.3 GO:0003351 epithelial cilium movement(GO:0003351)
0.0 0.0 GO:0061033 secretion by lung epithelial cell involved in lung growth(GO:0061033)
0.0 0.1 GO:0060586 multicellular organismal iron ion homeostasis(GO:0060586)
0.0 0.1 GO:0090611 ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611)
0.0 0.1 GO:1902728 positive regulation of skeletal muscle satellite cell proliferation(GO:1902724) positive regulation of growth factor dependent skeletal muscle satellite cell proliferation(GO:1902728)
0.0 0.2 GO:0045199 maintenance of epithelial cell apical/basal polarity(GO:0045199)
0.0 0.1 GO:0034146 toll-like receptor 5 signaling pathway(GO:0034146)
0.0 0.1 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.0 0.1 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.0 0.1 GO:0010764 negative regulation of fibroblast migration(GO:0010764)
0.0 0.1 GO:0060335 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.0 0.0 GO:0018008 N-terminal peptidyl-glycine N-myristoylation(GO:0018008)
0.0 0.0 GO:0001192 maintenance of transcriptional fidelity during DNA-templated transcription elongation(GO:0001192) maintenance of transcriptional fidelity during DNA-templated transcription elongation from RNA polymerase II promoter(GO:0001193)
0.0 0.1 GO:1901475 pyruvate transmembrane transport(GO:1901475)
0.0 0.1 GO:1903912 negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation(GO:1903912)
0.0 0.0 GO:0009992 cellular water homeostasis(GO:0009992)
0.0 0.1 GO:0035521 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359) monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.0 0.4 GO:0019432 triglyceride biosynthetic process(GO:0019432)
0.0 0.0 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.0 0.0 GO:0044341 sodium-dependent phosphate transport(GO:0044341)
0.0 0.2 GO:0070257 positive regulation of mucus secretion(GO:0070257)
0.0 0.0 GO:0033377 protein localization to secretory granule(GO:0033366) protein localization to mast cell secretory granule(GO:0033367) protease localization to mast cell secretory granule(GO:0033368) maintenance of protein location in mast cell secretory granule(GO:0033370) T cell secretory granule organization(GO:0033371) maintenance of protease location in mast cell secretory granule(GO:0033373) protein localization to T cell secretory granule(GO:0033374) protease localization to T cell secretory granule(GO:0033375) maintenance of protein location in T cell secretory granule(GO:0033377) maintenance of protease location in T cell secretory granule(GO:0033379) granzyme B localization to T cell secretory granule(GO:0033380) maintenance of granzyme B location in T cell secretory granule(GO:0033382)
0.0 0.0 GO:0034971 histone H3-R17 methylation(GO:0034971)
0.0 0.0 GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I(GO:0042590)
0.0 0.3 GO:0030574 collagen catabolic process(GO:0030574)
0.0 0.1 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.0 0.3 GO:0019731 antibacterial humoral response(GO:0019731)
0.0 0.0 GO:1902605 heterotrimeric G-protein complex assembly(GO:1902605)
0.0 0.1 GO:0071374 cellular response to parathyroid hormone stimulus(GO:0071374)
0.0 0.0 GO:0046016 regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432) positive regulation of transcription by glucose(GO:0046016)
0.0 0.1 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
0.0 0.2 GO:0097186 amelogenesis(GO:0097186)
0.0 0.0 GO:0015855 nucleobase transport(GO:0015851) pyrimidine nucleobase transport(GO:0015855)
0.0 0.1 GO:0008354 germ cell migration(GO:0008354) hematopoietic stem cell migration(GO:0035701)
0.0 0.0 GO:0061762 CAMKK-AMPK signaling cascade(GO:0061762)
0.0 0.1 GO:0035437 maintenance of protein localization in endoplasmic reticulum(GO:0035437)
0.0 0.1 GO:0009133 nucleoside diphosphate biosynthetic process(GO:0009133)
0.0 0.1 GO:0008655 pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
0.0 0.1 GO:2001199 negative regulation of dendritic cell differentiation(GO:2001199)
0.0 0.2 GO:0046415 urate metabolic process(GO:0046415)
0.0 0.1 GO:0006144 purine nucleobase metabolic process(GO:0006144)
0.0 0.1 GO:0016045 detection of bacterium(GO:0016045) detection of other organism(GO:0098543)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.9 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.1 0.3 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.1 0.8 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.1 0.3 GO:0005914 spot adherens junction(GO:0005914)
0.1 0.3 GO:0034687 integrin alphaL-beta2 complex(GO:0034687)
0.1 0.3 GO:0017133 mitochondrial electron transfer flavoprotein complex(GO:0017133) electron transfer flavoprotein complex(GO:0045251)
0.0 0.7 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.1 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.0 0.1 GO:0043512 inhibin-betaglycan-ActRII complex(GO:0034673) inhibin A complex(GO:0043512)
0.0 0.1 GO:0000802 transverse filament(GO:0000802)
0.0 0.1 GO:0044393 microspike(GO:0044393)
0.0 0.3 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867) insulin-like growth factor ternary complex(GO:0042567)
0.0 0.1 GO:0071149 TEAD-2-YAP complex(GO:0071149)
0.0 0.1 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
0.0 0.1 GO:0071953 elastic fiber(GO:0071953)
0.0 0.2 GO:0072559 NLRP3 inflammasome complex(GO:0072559)
0.0 0.3 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.1 GO:1902636 kinociliary basal body(GO:1902636)
0.0 0.1 GO:0035339 SPOTS complex(GO:0035339)
0.0 0.2 GO:0098574 cytoplasmic side of lysosomal membrane(GO:0098574)
0.0 0.3 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.0 0.1 GO:0044194 cytolytic granule(GO:0044194)
0.0 0.4 GO:0005767 secondary lysosome(GO:0005767)
0.0 0.1 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.0 0.1 GO:0031501 mannosyltransferase complex(GO:0031501)
0.0 0.2 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 0.1 GO:0072557 IPAF inflammasome complex(GO:0072557)
0.0 0.2 GO:0060091 kinocilium(GO:0060091)
0.0 0.2 GO:0097512 cardiac myofibril(GO:0097512)
0.0 0.1 GO:0002142 stereocilia ankle link complex(GO:0002142)
0.0 0.5 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.0 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.0 0.7 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.1 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.0 GO:1990584 cardiac Troponin complex(GO:1990584)
0.0 0.2 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.1 GO:0070826 paraferritin complex(GO:0070826)
0.0 0.3 GO:0071564 npBAF complex(GO:0071564)
0.0 0.1 GO:0035841 new growing cell tip(GO:0035841)
0.0 0.1 GO:0070876 SOSS complex(GO:0070876)
0.0 0.1 GO:1903439 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.0 0.1 GO:0019815 B cell receptor complex(GO:0019815)
0.0 0.2 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.1 GO:0097427 microtubule bundle(GO:0097427)
0.0 0.0 GO:1990851 Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.0 0.1 GO:0042825 TAP complex(GO:0042825)
0.0 0.2 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.1 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.0 GO:0005745 m-AAA complex(GO:0005745)
0.0 0.0 GO:0034774 secretory granule lumen(GO:0034774) cytoplasmic membrane-bounded vesicle lumen(GO:0060205)
0.0 0.0 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0052871 tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871)
0.3 1.1 GO:0016647 oxidoreductase activity, acting on the CH-NH group of donors, oxygen as acceptor(GO:0016647)
0.2 1.9 GO:0033691 sialic acid binding(GO:0033691)
0.2 0.7 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
0.2 0.5 GO:0048030 disaccharide binding(GO:0048030)
0.1 0.6 GO:0032217 riboflavin transporter activity(GO:0032217)
0.1 0.7 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.1 0.4 GO:0034617 tetrahydrobiopterin binding(GO:0034617)
0.1 0.3 GO:0045353 interleukin-1, Type II receptor binding(GO:0005151) interleukin-1 receptor antagonist activity(GO:0005152) interleukin-1 Type I receptor antagonist activity(GO:0045352) interleukin-1 Type II receptor antagonist activity(GO:0045353)
0.1 1.9 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.1 0.3 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.1 3.1 GO:0071949 FAD binding(GO:0071949)
0.1 0.6 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.1 0.3 GO:0004794 L-threonine ammonia-lyase activity(GO:0004794)
0.1 0.3 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.1 0.3 GO:0015232 heme transporter activity(GO:0015232)
0.1 0.3 GO:0016726 xanthine dehydrogenase activity(GO:0004854) oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor(GO:0016726)
0.1 0.3 GO:0030369 ICAM-3 receptor activity(GO:0030369)
0.1 0.3 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.1 0.2 GO:0004771 sterol esterase activity(GO:0004771) retinyl-palmitate esterase activity(GO:0050253)
0.1 0.6 GO:0003909 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.1 0.4 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.1 0.3 GO:0032810 sterol response element binding(GO:0032810)
0.1 0.2 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.1 0.2 GO:0016649 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.1 0.3 GO:0031849 olfactory receptor binding(GO:0031849)
0.1 0.4 GO:0004969 histamine receptor activity(GO:0004969)
0.1 0.2 GO:0019863 IgE binding(GO:0019863)
0.1 0.3 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.1 0.2 GO:0005118 sevenless binding(GO:0005118)
0.0 0.1 GO:0004974 leukotriene receptor activity(GO:0004974)
0.0 0.7 GO:0005132 type I interferon receptor binding(GO:0005132)
0.0 0.1 GO:0031686 A1 adenosine receptor binding(GO:0031686)
0.0 0.1 GO:0004967 glucagon receptor activity(GO:0004967)
0.0 0.6 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.1 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.0 0.2 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 1.4 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.2 GO:0019770 IgG receptor activity(GO:0019770)
0.0 0.1 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.0 0.1 GO:0015142 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.0 0.1 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.0 0.4 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.1 GO:0008147 structural constituent of bone(GO:0008147)
0.0 0.1 GO:0050252 retinol O-fatty-acyltransferase activity(GO:0050252)
0.0 0.2 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.0 0.1 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.0 0.3 GO:0003993 acid phosphatase activity(GO:0003993)
0.0 0.1 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.0 0.1 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.0 0.1 GO:0070051 fibrinogen binding(GO:0070051)
0.0 0.3 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.2 GO:0036374 glutathione hydrolase activity(GO:0036374)
0.0 0.2 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.0 0.2 GO:0072510 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.0 0.1 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.0 0.1 GO:0015182 L-asparagine transmembrane transporter activity(GO:0015182)
0.0 0.1 GO:0034041 sterol-transporting ATPase activity(GO:0034041)
0.0 0.2 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.0 0.4 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.4 GO:0008391 arachidonic acid monooxygenase activity(GO:0008391)
0.0 0.1 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.0 0.1 GO:0004342 glucosamine-6-phosphate deaminase activity(GO:0004342)
0.0 0.0 GO:0016743 carboxyl- or carbamoyltransferase activity(GO:0016743)
0.0 0.1 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.0 0.2 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.3 GO:0015245 fatty acid transporter activity(GO:0015245)
0.0 0.2 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.0 0.2 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.2 GO:0097322 7SK snRNA binding(GO:0097322)
0.0 0.2 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 0.1 GO:0071723 lipopeptide binding(GO:0071723)
0.0 0.1 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 0.1 GO:0097603 temperature-gated ion channel activity(GO:0097603)
0.0 0.1 GO:0004145 diamine N-acetyltransferase activity(GO:0004145)
0.0 0.1 GO:0004515 nicotinamide-nucleotide adenylyltransferase activity(GO:0000309) nicotinate-nucleotide adenylyltransferase activity(GO:0004515)
0.0 0.1 GO:0002046 opsin binding(GO:0002046)
0.0 0.4 GO:0005402 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402)
0.0 0.1 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 0.1 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.1 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.2 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.1 GO:0001851 complement component C3b binding(GO:0001851)
0.0 0.3 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.0 GO:0016015 morphogen activity(GO:0016015)
0.0 0.0 GO:0015389 purine nucleobase transmembrane transporter activity(GO:0005345) pyrimidine nucleobase transmembrane transporter activity(GO:0005350) nucleobase transmembrane transporter activity(GO:0015205) pyrimidine- and adenine-specific:sodium symporter activity(GO:0015389)
0.0 0.1 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.0 0.2 GO:0050308 sugar-phosphatase activity(GO:0050308)
0.0 0.1 GO:0032027 myosin light chain binding(GO:0032027)
0.0 0.1 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086) lead ion transmembrane transporter activity(GO:0015094) vanadium ion transmembrane transporter activity(GO:0015100) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.0 0.1 GO:0004875 complement receptor activity(GO:0004875)
0.0 0.0 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.0 0.1 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.0 0.2 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.1 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.0 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.0 0.2 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.1 GO:0046978 TAP1 binding(GO:0046978) TAP2 binding(GO:0046979)
0.0 0.0 GO:0004379 glycylpeptide N-tetradecanoyltransferase activity(GO:0004379) myristoyltransferase activity(GO:0019107)
0.0 0.1 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.0 0.1 GO:0034711 inhibin binding(GO:0034711)
0.0 0.1 GO:0097643 amylin receptor activity(GO:0097643)
0.0 0.1 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.0 0.0 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.0 0.0 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.0 2.0 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.0 GO:0071936 coreceptor activity involved in Wnt signaling pathway(GO:0071936)
0.0 0.4 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.3 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.1 GO:0038132 neuregulin binding(GO:0038132)
0.0 0.1 GO:0004565 beta-galactosidase activity(GO:0004565)
0.0 0.5 GO:0016504 peptidase activator activity(GO:0016504)
0.0 0.1 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0 0.2 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.3 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.0 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.0 0.0 GO:0004096 catalase activity(GO:0004096)
0.0 0.1 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 0.0 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.0 0.0 GO:0052796 exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997) exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.0 0.1 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.0 GO:0008169 C-methyltransferase activity(GO:0008169)
0.0 0.1 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.0 0.0 GO:0016838 carbon-oxygen lyase activity, acting on phosphates(GO:0016838)
0.0 0.0 GO:0004911 interleukin-2 receptor activity(GO:0004911)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 1.0 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.5 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 1.2 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 2.0 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.9 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.5 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.8 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.6 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.4 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.4 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.5 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.3 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.0 0.4 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.1 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.0 0.9 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.2 REACTOME TRAF6 MEDIATED INDUCTION OF TAK1 COMPLEX Genes involved in TRAF6 mediated induction of TAK1 complex
0.0 0.1 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.2 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.0 0.2 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.5 REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.0 0.5 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.1 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.1 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.4 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.1 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 1.0 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway