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2D miR_HR1_12

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Results for Mga

Z-value: 0.54

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Transcription factors associated with Mga

Gene Symbol Gene ID Gene Info
ENSMUSG00000033943.9 MAX gene associated

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Mgamm10_v2_chr2_+_119897212_119897305-0.283.9e-01Click!

Activity profile of Mga motif

Sorted Z-values of Mga motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_171419027 1.14 ENSMUST00000171362.1
thiosulfate sulfurtransferase (rhodanese)-like domain containing 1
chr6_-_129237948 1.09 ENSMUST00000181238.1
ENSMUST00000180379.1
RIKEN cDNA 2310001H17 gene
chr3_+_105870898 0.70 ENSMUST00000010279.5
adenosine A3 receptor
chr4_+_95967322 0.58 ENSMUST00000107083.1
hook homolog 1 (Drosophila)
chr7_-_3720382 0.58 ENSMUST00000078451.6
paired Ig-like receptor B
chr11_+_83703991 0.53 ENSMUST00000092836.5
WAP four-disulfide core domain 17
chr6_-_149188648 0.49 ENSMUST00000095319.3
ENSMUST00000141346.1
ENSMUST00000111535.1
antagonist of mitotic exit network 1
chr11_-_3931960 0.48 ENSMUST00000109990.1
ENSMUST00000020710.4
ENSMUST00000109989.3
ENSMUST00000109991.1
ENSMUST00000109993.2
transcobalamin 2
chr10_+_81575257 0.48 ENSMUST00000135211.1
transducin-like enhancer of split 2, homolog of Drosophila E(spl)
chr10_+_81575306 0.48 ENSMUST00000146916.1
transducin-like enhancer of split 2, homolog of Drosophila E(spl)
chr2_-_129371131 0.45 ENSMUST00000028881.7
interleukin 1 beta
chr11_-_121039400 0.43 ENSMUST00000026159.5
CD7 antigen
chr12_+_35992900 0.37 ENSMUST00000020898.5
anterior gradient 2
chr7_-_30880263 0.37 ENSMUST00000108125.2
CD22 antigen
chr17_-_6948283 0.35 ENSMUST00000024572.9
radial spoke 3B homolog (Chlamydomonas)
chr14_+_64652524 0.33 ENSMUST00000100473.4
kinesin family member 13B
chr11_+_116532441 0.32 ENSMUST00000106386.1
ENSMUST00000145737.1
ENSMUST00000155102.1
ENSMUST00000063446.6
sphingosine kinase 1
chr8_+_12984246 0.30 ENSMUST00000110873.3
ENSMUST00000173006.1
ENSMUST00000145067.1
mcf.2 transforming sequence-like
chr13_+_29016267 0.28 ENSMUST00000140415.1
RIKEN cDNA A330102I10 gene
chr6_-_41636389 0.27 ENSMUST00000031902.5
transient receptor potential cation channel, subfamily V, member 6
chr5_+_129941949 0.26 ENSMUST00000051758.7
ENSMUST00000073945.4
vitamin K epoxide reductase complex, subunit 1-like 1
chr2_+_151996505 0.26 ENSMUST00000109859.2
ENSMUST00000073228.5
solute carrier protein family 52, member 3
chr3_+_87376381 0.25 ENSMUST00000163661.1
ENSMUST00000072480.2
ENSMUST00000167200.1
Fc receptor-like 1
chr17_+_34305883 0.24 ENSMUST00000074557.8
histocompatibility 2, class II antigen E beta
chr6_+_123229843 0.24 ENSMUST00000112554.2
ENSMUST00000024118.4
ENSMUST00000117130.1
C-type lectin domain family 4, member n
chr17_+_7945653 0.24 ENSMUST00000097423.2
radial spoke 3A homolog (Chlamydomonas)
chr6_+_5390387 0.23 ENSMUST00000183358.1
ankyrin repeat and SOCS box-containing 4
chr1_+_75435930 0.22 ENSMUST00000037796.7
ENSMUST00000113584.1
ENSMUST00000145166.1
ENSMUST00000143730.1
ENSMUST00000133418.1
ENSMUST00000144874.1
ENSMUST00000140287.1
GDP-mannose pyrophosphorylase A
chr4_+_132564051 0.22 ENSMUST00000070690.7
platelet-activating factor receptor
chr16_-_45844303 0.22 ENSMUST00000036355.6
pleckstrin homology-like domain, family B, member 2
chr11_+_116531744 0.21 ENSMUST00000106387.2
ENSMUST00000100201.3
sphingosine kinase 1
chr1_-_130462680 0.21 ENSMUST00000027650.6
CD55 antigen
chr7_+_27486910 0.21 ENSMUST00000008528.7
SERTA domain containing 1
chr2_+_55411790 0.21 ENSMUST00000155997.1
ENSMUST00000128307.1
predicted gene 14033
chr17_+_23679363 0.20 ENSMUST00000024699.2
claudin 6
chr3_+_105870858 0.20 ENSMUST00000164730.1
adenosine A3 receptor
chr11_+_21572221 0.20 ENSMUST00000020568.3
ENSMUST00000131135.1
WD repeat containing planar cell polarity effector
chr11_+_113657375 0.20 ENSMUST00000148736.1
ENSMUST00000142069.1
ENSMUST00000134418.1
component of oligomeric golgi complex 1
chr1_+_190928822 0.20 ENSMUST00000135364.1
angel homolog 2 (Drosophila)
chr17_-_32350569 0.20 ENSMUST00000050214.7
A kinase (PRKA) anchor protein 8-like
chr2_-_170131156 0.19 ENSMUST00000063710.6
zinc finger protein 217
chr1_+_75436002 0.19 ENSMUST00000131545.1
ENSMUST00000141124.1
GDP-mannose pyrophosphorylase A
chr14_-_52279238 0.19 ENSMUST00000167116.1
ENSMUST00000100631.4
RAB2B, member RAS oncogene family
chr10_+_115384951 0.18 ENSMUST00000036044.8
zinc finger, C3H1-type containing
chr8_+_3393018 0.18 ENSMUST00000004684.6
ENSMUST00000145394.1
rho/rac guanine nucleotide exchange factor (GEF) 18
chrX_+_163909132 0.17 ENSMUST00000033734.7
ENSMUST00000112294.2
adaptor-related protein complex 1, sigma 2 subunit
chr10_+_70868633 0.17 ENSMUST00000058942.5
RIKEN cDNA 4930533K18 gene
chr1_-_130423009 0.17 ENSMUST00000112488.2
ENSMUST00000119432.1
decay accelerating factor 2
chr9_-_117252450 0.16 ENSMUST00000111773.3
ENSMUST00000068962.7
ENSMUST00000044901.7
RNA binding motif, single stranded interacting protein
chr7_-_24316590 0.16 ENSMUST00000108436.1
ENSMUST00000032673.8
zinc finger protein 94
chr8_+_83165348 0.16 ENSMUST00000034145.4
TBC1 domain family, member 9
chr10_+_79669410 0.15 ENSMUST00000020552.5
tubulin polyglutamylase complex subunit 1
chr9_-_109568262 0.15 ENSMUST00000056745.6
F-box and WD-40 domain protein 15
chrX_+_35888808 0.14 ENSMUST00000033419.6
dedicator of cytokinesis 11
chr5_+_149265035 0.14 ENSMUST00000130144.1
ENSMUST00000071130.3
arachidonate 5-lipoxygenase activating protein
chr5_-_120777628 0.14 ENSMUST00000044833.8
2'-5' oligoadenylate synthetase 3
chr13_-_8870967 0.14 ENSMUST00000164183.2
WD repeat domain 37
chr18_+_20944607 0.13 ENSMUST00000050004.1
ring finger protein 125
chr14_-_55900188 0.13 ENSMUST00000111325.3
short chain dehydrogenase/reductase family 39U, member 1
chr1_+_60409612 0.13 ENSMUST00000052332.8
abl-interactor 2
chr6_+_56924022 0.13 ENSMUST00000176838.1
vomeronasal 1 receptor 4
chr7_+_5080214 0.12 ENSMUST00000098845.3
ENSMUST00000146317.1
ENSMUST00000153169.1
ENSMUST00000045277.6
epsin 1
chr10_+_75212065 0.12 ENSMUST00000105421.2
sperm antigen with calponin homology and coiled-coil domains 1-like
chr5_+_139378163 0.12 ENSMUST00000138631.1
ENSMUST00000053120.4
G protein-coupled receptor 146
RIKEN cDNA D830046C22 gene
chr15_-_43869993 0.08 ENSMUST00000067469.4
transmembrane protein 74
chr14_-_18893623 0.08 ENSMUST00000177259.1
ubiquitin-conjugating enzyme E2E 2
chr9_+_57940104 0.08 ENSMUST00000043059.7
sema domain, immunoglobulin domain (Ig), and GPI membrane anchor, (semaphorin) 7A
chr3_+_76075583 0.08 ENSMUST00000160261.1
follistatin-like 5
chr11_+_116531097 0.07 ENSMUST00000138840.1
sphingosine kinase 1
chr13_-_74482943 0.07 ENSMUST00000074369.6
zinc finger protein 825
chr12_-_54695885 0.07 ENSMUST00000067272.8
E2F-associated phosphoprotein
chr13_-_113180897 0.07 ENSMUST00000038212.7
granzyme K
chr17_-_7827289 0.07 ENSMUST00000167580.1
ENSMUST00000169126.1
fibronectin type III domain containing 1
chr2_+_83644435 0.07 ENSMUST00000081591.6
zinc finger CCCH-type containing 15
chr11_+_49203465 0.06 ENSMUST00000150284.1
ENSMUST00000109197.1
ENSMUST00000151228.1
zinc finger protein 62
chr5_-_138619751 0.06 ENSMUST00000085852.4
ENSMUST00000110905.2
zinc finger protein 68
chr8_-_13974715 0.06 ENSMUST00000119182.1
ENSMUST00000062613.4
testis development related protein
chr6_-_56923927 0.06 ENSMUST00000031793.5
5'-nucleotidase, cytosolic III
chr9_-_97111117 0.06 ENSMUST00000085206.4
solute carrier family 25, member 36
chr2_-_132145057 0.05 ENSMUST00000028815.8
solute carrier family 23 (nucleobase transporters), member 2
chr11_-_21572193 0.05 ENSMUST00000102874.4
malate dehydrogenase 1, NAD (soluble)
chr15_-_66801577 0.05 ENSMUST00000168589.1
src-like adaptor
chr12_-_54695829 0.04 ENSMUST00000162106.1
ENSMUST00000160085.1
ENSMUST00000161592.1
ENSMUST00000163433.1
E2F-associated phosphoprotein
chr16_-_62786742 0.04 ENSMUST00000152553.1
ENSMUST00000063089.5
NOL1/NOP2/Sun domain family member 3
chr9_-_109626059 0.04 ENSMUST00000073962.6
F-box and WD-40 domain protein 24
chr3_+_13946368 0.04 ENSMUST00000171075.1
ENSMUST00000108372.2
RALY RNA binding protein-like
chr1_+_170214826 0.03 ENSMUST00000159201.1
ENSMUST00000055830.1
RIKEN cDNA 4930500M09 gene
chr11_+_49203285 0.03 ENSMUST00000109198.1
ENSMUST00000137061.2
zinc finger protein 62
chr7_+_24081888 0.03 ENSMUST00000068975.3
zinc finger protein 180
chr11_-_8973266 0.03 ENSMUST00000154153.1
polycystic kidney disease 1 like 1
chr13_-_8870999 0.03 ENSMUST00000177404.1
ENSMUST00000176922.1
ENSMUST00000021572.4
WD repeat domain 37
chr5_-_115134907 0.02 ENSMUST00000060798.5
unc-119 homolog B (C. elegans)
chr5_-_138619653 0.02 ENSMUST00000129832.1
zinc finger protein 68
chr4_+_43381979 0.02 ENSMUST00000035645.5
ENSMUST00000144911.1
RUN and SH3 domain containing 2
chr9_-_85749308 0.02 ENSMUST00000039213.8
inhibitor of Bruton agammaglobulinemia tyrosine kinase
chr8_-_61902669 0.02 ENSMUST00000121785.1
ENSMUST00000034057.7
palladin, cytoskeletal associated protein
chr8_-_105979413 0.02 ENSMUST00000034371.7
dipeptidase 3
chr7_-_7337493 0.01 ENSMUST00000072475.6
ENSMUST00000174368.1
vomeronasal 2, receptor 30
chr7_-_4603105 0.01 ENSMUST00000049113.7
protein tyrosine phosphatase, receptor type, H
chr2_+_85136355 0.01 ENSMUST00000057019.7
apelin receptor
chr5_-_137921612 0.01 ENSMUST00000031741.7
cytochrome P450, family 3, subfamily a, polypeptide 13
chr5_-_138619702 0.01 ENSMUST00000063262.4
zinc finger protein 68
chr16_-_36131156 0.00 ENSMUST00000161638.1
ENSMUST00000096090.2
cystatin A

Network of associatons between targets according to the STRING database.

First level regulatory network of Mga

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.1 0.4 GO:1903896 positive regulation of IRE1-mediated unfolded protein response(GO:1903896)
0.1 0.5 GO:0033092 positive regulation of immature T cell proliferation in thymus(GO:0033092) negative regulation of adiponectin secretion(GO:0070164)
0.1 0.9 GO:0002441 histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553)
0.1 0.3 GO:0018214 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.1 0.5 GO:0015889 cobalamin transport(GO:0015889)
0.1 0.2 GO:1902943 regulation of voltage-gated chloride channel activity(GO:1902941) positive regulation of voltage-gated chloride channel activity(GO:1902943)
0.1 0.2 GO:0030450 regulation of complement activation, classical pathway(GO:0030450)
0.1 0.3 GO:0032218 riboflavin transport(GO:0032218)
0.0 0.2 GO:0090521 glomerular visceral epithelial cell migration(GO:0090521)
0.0 0.1 GO:0002540 leukotriene production involved in inflammatory response(GO:0002540)
0.0 0.2 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0 0.6 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.0 0.3 GO:1990035 parathyroid hormone secretion(GO:0035898) calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.0 0.2 GO:0010793 regulation of mRNA export from nucleus(GO:0010793)
0.0 0.2 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.0 0.1 GO:0060700 regulation of ribonuclease activity(GO:0060700)
0.0 0.2 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.2 GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.0 0.0 GO:0015882 L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904)
0.0 0.1 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.0 GO:0002946 tRNA C5-cytosine methylation(GO:0002946)
0.0 0.6 GO:0008333 endosome to lysosome transport(GO:0008333)
0.0 0.1 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.0 0.1 GO:0072531 pyrimidine-containing compound transmembrane transport(GO:0072531)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0070695 FHF complex(GO:0070695)
0.0 0.1 GO:0098888 extrinsic component of presynaptic membrane(GO:0098888)
0.0 0.2 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.1 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 0.2 GO:0070545 PeBoW complex(GO:0070545)
0.0 0.2 GO:0045180 basal cortex(GO:0045180)
0.0 0.2 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.3 GO:0033270 paranode region of axon(GO:0033270)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0008481 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.1 0.9 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.1 0.3 GO:0032217 riboflavin transporter activity(GO:0032217)
0.1 0.5 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.1 GO:0004051 arachidonate 5-lipoxygenase activity(GO:0004051)
0.0 0.2 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.0 0.1 GO:0005550 pheromone binding(GO:0005550)
0.0 0.2 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.0 0.4 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.5 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.4 GO:0001618 virus receptor activity(GO:0001618)
0.0 0.3 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.0 GO:0015229 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.0 0.0 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
0.0 0.4 GO:0015026 coreceptor activity(GO:0015026)
0.0 0.3 GO:0048038 quinone binding(GO:0048038)
0.0 0.6 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 0.1 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.0 0.1 GO:0035615 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.6 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 0.2 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.0 0.4 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.2 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.6 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 1.0 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.2 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression