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2D miR_HR1_12

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Results for Cdc5l

Z-value: 0.56

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Transcription factors associated with Cdc5l

Gene Symbol Gene ID Gene Info
ENSMUSG00000023932.8 cell division cycle 5-like (S. pombe)

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Cdc5lmm10_v2_chr17_-_45433682_45433709-0.652.3e-02Click!

Activity profile of Cdc5l motif

Sorted Z-values of Cdc5l motif

Promoter Log-likelihood Transcript Gene Gene Info
chr7_-_101869012 1.08 ENSMUST00000123321.1
folate receptor 1 (adult)
chr7_-_101868667 1.06 ENSMUST00000150184.1
folate receptor 1 (adult)
chr13_-_18382041 0.76 ENSMUST00000139064.2
ENSMUST00000175703.2
POU domain, class 6, transcription factor 2
chr5_+_20702129 0.72 ENSMUST00000101556.4
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr5_-_136883115 0.64 ENSMUST00000057497.6
ENSMUST00000111103.1
collagen, type XXVI, alpha 1
chr4_-_149126688 0.63 ENSMUST00000030815.2
cortistatin
chr8_+_109990430 0.53 ENSMUST00000001720.7
ENSMUST00000143741.1
tyrosine aminotransferase
chr5_+_66968416 0.49 ENSMUST00000038188.7
LIM and calponin homology domains 1
chr1_+_143640664 0.43 ENSMUST00000038252.2
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
chr2_+_58755177 0.40 ENSMUST00000102755.3
uridine phosphorylase 2
chr11_+_59306920 0.37 ENSMUST00000000128.3
ENSMUST00000108783.3
wingless-type MMTV integration site 9A
chr14_+_73237891 0.37 ENSMUST00000044405.6
lysophosphatidic acid receptor 6
chr18_-_22850738 0.35 ENSMUST00000092015.4
ENSMUST00000069215.6
nucleolar protein 4
chr3_-_83049797 0.34 ENSMUST00000048246.3
fibrinogen beta chain
chr12_+_74297474 0.34 ENSMUST00000072100.3
DNA binding protein with his-thr domain
chr5_+_107497718 0.32 ENSMUST00000112671.2
RIKEN cDNA A830010M20 gene
chr17_+_47140942 0.29 ENSMUST00000077951.7
transcriptional regulating factor 1
chr2_+_106695594 0.29 ENSMUST00000016530.7
metallophosphoesterase domain containing 2
chr6_+_88724828 0.28 ENSMUST00000089449.2
monoglyceride lipase
chr1_+_109993982 0.27 ENSMUST00000027542.6
cadherin 7, type 2
chr5_+_107497762 0.27 ENSMUST00000152474.1
ENSMUST00000060553.7
RIKEN cDNA A830010M20 gene
chr6_+_86526271 0.25 ENSMUST00000180896.1
RIKEN cDNA 1600020E01 gene
chr6_+_142298419 0.24 ENSMUST00000041993.2
islet amyloid polypeptide
chr5_+_66968559 0.22 ENSMUST00000127184.1
LIM and calponin homology domains 1
chrX_+_136822781 0.18 ENSMUST00000113085.1
proteolipid protein (myelin) 1
chr10_+_23938572 0.18 ENSMUST00000079134.4
trace amine-associated receptor 2
chr4_-_119383732 0.17 ENSMUST00000044781.2
ENSMUST00000084307.3
coiled-coil domain containing 30
chrX_+_136822671 0.17 ENSMUST00000033800.6
proteolipid protein (myelin) 1
chr12_+_59129720 0.15 ENSMUST00000175912.1
ENSMUST00000176892.1
CTAGE family, member 5
chr19_+_26749726 0.14 ENSMUST00000175842.1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr4_+_95967205 0.14 ENSMUST00000030306.7
hook homolog 1 (Drosophila)
chr12_+_59129757 0.13 ENSMUST00000069430.8
ENSMUST00000177370.1
CTAGE family, member 5
chr2_+_126034967 0.12 ENSMUST00000110442.1
fibroblast growth factor 7
chr5_-_31220491 0.12 ENSMUST00000031032.7
protein phosphatase 1G (formerly 2C), magnesium-dependent, gamma isoform
chr10_+_17723220 0.10 ENSMUST00000038107.7
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
chr9_-_96752822 0.09 ENSMUST00000152594.1
zinc finger and BTB domain containing 38
chr3_-_49757257 0.09 ENSMUST00000035931.7
protocadherin 18
chr1_+_180330470 0.07 ENSMUST00000070181.6
inositol 1,4,5-trisphosphate 3-kinase B
chr14_+_66635251 0.06 ENSMUST00000159365.1
ENSMUST00000054661.1
ENSMUST00000159068.1
adrenergic receptor, alpha 1a
chr16_+_36184082 0.02 ENSMUST00000114858.1
predicted gene 5483

Network of associatons between targets according to the STRING database.

First level regulatory network of Cdc5l

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.1 GO:0061713 neural crest cell migration involved in heart formation(GO:0003147) anterior neural tube closure(GO:0061713) cellular response to folic acid(GO:0071231)
0.1 0.5 GO:0006572 tyrosine catabolic process(GO:0006572)
0.1 0.3 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.1 0.7 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.0 0.4 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.1 GO:0061033 secretion by lung epithelial cell involved in lung growth(GO:0061033)
0.0 0.3 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.0 0.2 GO:0097647 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.0 0.1 GO:0061428 adrenal cortex development(GO:0035801) adrenal cortex formation(GO:0035802) embryonic heart tube left/right pattern formation(GO:0060971) negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428)
0.0 0.6 GO:0045187 regulation of circadian sleep/wake cycle, sleep(GO:0045187)
0.0 0.1 GO:0001983 baroreceptor response to increased systemic arterial blood pressure(GO:0001983) positive regulation of the force of heart contraction by epinephrine-norepinephrine(GO:0001997) positive regulation of the force of heart contraction by chemical signal(GO:0003099)
0.0 0.4 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.0 0.1 GO:0033030 negative regulation of neutrophil apoptotic process(GO:0033030)
0.0 0.1 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.0 0.4 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.0 0.4 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.1 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.4 GO:0045098 type III intermediate filament(GO:0045098)
0.0 0.7 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.3 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.1 GO:0070695 FHF complex(GO:0070695)
0.0 0.3 GO:0043196 varicosity(GO:0043196)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.1 GO:0051870 methotrexate binding(GO:0051870)
0.2 0.5 GO:0070546 L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.1 0.4 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.1 0.7 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 0.4 GO:0004850 uridine phosphorylase activity(GO:0004850)
0.1 0.4 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.0 0.4 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.6 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.1 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.0 0.2 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.3 GO:0047372 acylglycerol lipase activity(GO:0047372)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.3 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.3 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.4 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.7 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.3 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis