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2D miR_HR1_12

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Results for Zbtb18

Z-value: 1.31

Motif logo

Transcription factors associated with Zbtb18

Gene Symbol Gene ID Gene Info
ENSMUSG00000063659.6 zinc finger and BTB domain containing 18

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Zbtb18mm10_v2_chr1_+_177444653_177444669-0.745.8e-03Click!

Activity profile of Zbtb18 motif

Sorted Z-values of Zbtb18 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr6_+_78405148 4.60 ENSMUST00000023906.2
regenerating islet-derived 2
chr8_-_111691002 2.82 ENSMUST00000034435.5
chymotrypsinogen B1
chr14_+_30886476 2.18 ENSMUST00000006703.6
ENSMUST00000078490.5
ENSMUST00000120269.2
inter alpha-trypsin inhibitor, heavy chain 4
chr4_-_141825997 2.15 ENSMUST00000102481.3
chymotrypsin-like elastase family, member 2A
chr8_-_105933832 1.95 ENSMUST00000034368.6
chymotrypsin-like
chr11_+_99047311 1.83 ENSMUST00000140772.1
insulin-like growth factor binding protein 4
chr11_-_107794557 1.83 ENSMUST00000021066.3
calcium channel, voltage-dependent, gamma subunit 4
chr11_+_82115180 1.75 ENSMUST00000009329.2
chemokine (C-C motif) ligand 8
chr1_+_93006328 1.74 ENSMUST00000059676.4
aquaporin 12
chr14_+_30886521 1.65 ENSMUST00000168782.1
inter alpha-trypsin inhibitor, heavy chain 4
chr7_+_44225430 1.55 ENSMUST00000075162.3
kallikrein 1
chr4_-_130275542 1.45 ENSMUST00000154846.1
ENSMUST00000105996.1
serine incorporator 2
chr1_+_45311538 1.38 ENSMUST00000087883.6
collagen, type III, alpha 1
chrX_-_8018492 1.38 ENSMUST00000033503.2
glyoxalase domain containing 5
chr6_+_39420378 1.37 ENSMUST00000090237.2
predicted gene 10244
chr6_-_41035501 1.36 ENSMUST00000031931.5
RIKEN cDNA 2210010C04 gene
chr11_-_95514570 1.35 ENSMUST00000058866.7
neurexophilin 3
chr6_+_70726430 1.34 ENSMUST00000103410.1
immunoglobulin kappa constant
chr14_+_118854695 1.31 ENSMUST00000100314.3
claudin 10
chr6_+_7555053 1.29 ENSMUST00000090679.2
ENSMUST00000184986.1
tachykinin 1
chr12_-_103457195 1.27 ENSMUST00000044687.6
interferon, alpha-inducible protein 27 like 2B
chr4_+_141242850 1.26 ENSMUST00000138096.1
ENSMUST00000006618.2
ENSMUST00000125392.1
Rho guanine nucleotide exchange factor (GEF) 19
chr17_-_28560704 1.23 ENSMUST00000114785.1
ENSMUST00000025062.3
colipase, pancreatic
chr2_-_28563362 1.23 ENSMUST00000028161.5
carboxyl ester lipase
chr14_+_103046977 1.22 ENSMUST00000022722.6
immunoresponsive gene 1
chr5_-_92328068 1.20 ENSMUST00000113093.3
chemokine (C-X-C motif) ligand 9
chr4_-_130279205 1.11 ENSMUST00000120126.2
serine incorporator 2
chr15_+_78926720 1.09 ENSMUST00000089377.5
lectin, galactose binding, soluble 1
chr5_+_135353295 1.08 ENSMUST00000111180.2
ENSMUST00000065785.3
tripartite motif-containing 50
chr7_+_43950614 1.04 ENSMUST00000072204.4
kallikrein 1-related peptidase b8
chr3_+_94933041 0.93 ENSMUST00000090839.5
selenium binding protein 1
chr1_+_164796723 0.93 ENSMUST00000027861.4
dermatopontin
chr6_+_37530173 0.92 ENSMUST00000040987.7
aldo-keto reductase family 1, member D1
chr7_-_79848191 0.92 ENSMUST00000107392.1
alanyl (membrane) aminopeptidase
chr3_+_90603767 0.91 ENSMUST00000001046.5
ENSMUST00000107330.1
S100 calcium binding protein A4
chr5_-_37717122 0.87 ENSMUST00000094836.4
serine/threonine kinase 32B
chr11_-_109722214 0.85 ENSMUST00000020938.7
family with sequence similarity 20, member A
chr5_+_141856692 0.82 ENSMUST00000074546.6
sidekick homolog 1 (chicken)
chr11_-_119086221 0.82 ENSMUST00000026665.7
chromobox 4
chr5_-_120812506 0.81 ENSMUST00000117193.1
ENSMUST00000130045.1
2'-5' oligoadenylate synthetase 1C
chr13_-_49215978 0.81 ENSMUST00000048946.6
RIKEN cDNA 1110007C09 gene
chr10_-_80139347 0.78 ENSMUST00000105369.1
downstream of Stk11
chr11_-_59182810 0.78 ENSMUST00000108793.2
gap junction protein, gamma 2
chr7_-_101869307 0.77 ENSMUST00000140584.1
ENSMUST00000134145.1
folate receptor 1 (adult)
chr5_-_108448882 0.77 ENSMUST00000031455.3
major facilitator superfamily domain containing 7A
chr4_+_43957678 0.73 ENSMUST00000107855.1
GLI pathogenesis-related 2
chr6_+_112273758 0.73 ENSMUST00000032376.5
LIM and cysteine-rich domains 1
chr8_+_13435459 0.71 ENSMUST00000167071.1
ENSMUST00000167505.1
transmembrane protein 255B
chr12_+_112678803 0.70 ENSMUST00000174780.1
ENSMUST00000169593.1
ENSMUST00000173942.1
zinc finger and BTB domain containing 42
chr11_+_87582201 0.70 ENSMUST00000133202.1
septin 4
chr2_+_43555321 0.70 ENSMUST00000028223.2
kynureninase (L-kynurenine hydrolase)
chr2_-_27247260 0.69 ENSMUST00000102886.3
ENSMUST00000129975.1
sarcosine dehydrogenase
chr6_-_129237948 0.68 ENSMUST00000181238.1
ENSMUST00000180379.1
RIKEN cDNA 2310001H17 gene
chr1_+_120006980 0.68 ENSMUST00000072886.4
secretin receptor
chrX_-_37668764 0.67 ENSMUST00000096457.4
reproductive homeobox 3H
chr1_-_150466165 0.66 ENSMUST00000162367.1
ENSMUST00000161611.1
ENSMUST00000161320.1
ENSMUST00000159035.1
proteoglycan 4 (megakaryocyte stimulating factor, articular superficial zone protein)
chr7_-_143074037 0.66 ENSMUST00000136602.1
transient receptor potential cation channel, subfamily M, member 5
chr7_-_4844665 0.64 ENSMUST00000066041.5
ENSMUST00000172377.1
shisa homolog 7 (Xenopus laevis)
chr7_-_19699008 0.64 ENSMUST00000174355.1
ENSMUST00000172983.1
ENSMUST00000174710.1
ENSMUST00000167646.2
ENSMUST00000003066.9
ENSMUST00000174064.1
apolipoprotein E
chr7_+_145300889 0.64 ENSMUST00000117718.1
MAS-related GPR, member F
chr7_-_19676749 0.63 ENSMUST00000003074.9
apolipoprotein C-II
chr9_-_103219823 0.63 ENSMUST00000168142.1
transferrin
chr6_+_139843648 0.63 ENSMUST00000087657.6
phosphatidylinositol 3-kinase, C2 domain containing, gamma polypeptide
chr4_-_130275523 0.63 ENSMUST00000146478.1
serine incorporator 2
chr7_+_145300806 0.63 ENSMUST00000033386.5
MAS-related GPR, member F
chr4_+_115088708 0.62 ENSMUST00000171877.1
ENSMUST00000177647.1
ENSMUST00000106548.2
ENSMUST00000030488.2
PDZK1 interacting protein 1
chr1_-_136960427 0.61 ENSMUST00000027649.7
nuclear receptor subfamily 5, group A, member 2
chr9_-_20976762 0.61 ENSMUST00000054197.5
sphingosine-1-phosphate receptor 2
chr6_-_123289862 0.61 ENSMUST00000032239.4
ENSMUST00000177367.1
C-type lectin domain family 4, member e
chr16_+_17276662 0.61 ENSMUST00000069420.4
transmembrane protein 191C
chr5_-_113800356 0.60 ENSMUST00000160374.1
ENSMUST00000067853.5
transmembrane protein 119
chr10_+_63061582 0.60 ENSMUST00000020266.8
ENSMUST00000178684.1
phenazine biosynthesis-like protein domain containing 1
chr10_+_77530252 0.58 ENSMUST00000000299.7
ENSMUST00000131023.1
ENSMUST00000130059.1
integrin beta 2
chr5_+_52190650 0.58 ENSMUST00000180601.1
RIKEN cDNA 9230114K14 gene
chr3_+_27371351 0.58 ENSMUST00000057186.1
growth hormone secretagogue receptor
chr2_+_155013531 0.58 ENSMUST00000029123.2
nonagouti
chr1_-_37541003 0.58 ENSMUST00000151952.1
mannoside acetylglucosaminyltransferase 4, isoenzyme A
chr10_-_53647080 0.57 ENSMUST00000169866.1
family with sequence similarity 184, member A
chr1_-_171059390 0.57 ENSMUST00000164044.1
ENSMUST00000169017.1
Fc receptor, IgG, low affinity III
chr18_-_78206408 0.57 ENSMUST00000163367.1
solute carrier family 14 (urea transporter), member 2
chr9_+_45403138 0.57 ENSMUST00000041005.5
FXYD domain-containing ion transport regulator 2
chr7_-_31110997 0.57 ENSMUST00000039435.8
hepsin
chr5_+_139389785 0.57 ENSMUST00000100514.2
G protein-coupled receptor 146
chr16_+_17276291 0.54 ENSMUST00000164950.1
ENSMUST00000159242.1
transmembrane protein 191C
chr10_+_93897156 0.54 ENSMUST00000180815.1
RIKEN cDNA 4930471D02 gene
chr10_+_127514939 0.54 ENSMUST00000035735.9
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4-like 2
chr11_-_94474088 0.53 ENSMUST00000107786.1
ENSMUST00000107791.1
ENSMUST00000103166.2
ENSMUST00000107792.1
ENSMUST00000100561.3
ENSMUST00000107793.1
ENSMUST00000107788.1
ENSMUST00000107790.1
ENSMUST00000107789.1
ENSMUST00000107785.1
ENSMUST00000021234.8
calcium channel, voltage-dependent, T type, alpha 1G subunit
chr2_-_150904620 0.53 ENSMUST00000056149.8
abhydrolase domain containing 12
chr1_-_162866502 0.53 ENSMUST00000046049.7
flavin containing monooxygenase 1
chr16_-_56886131 0.52 ENSMUST00000023435.5
transmembrane protein 45a
chr15_+_31568791 0.52 ENSMUST00000162532.1
carboxymethylenebutenolidase-like (Pseudomonas)
chr4_+_43957401 0.51 ENSMUST00000030202.7
GLI pathogenesis-related 2
chrX_-_102906469 0.51 ENSMUST00000120808.1
ENSMUST00000121197.1
DMRT-like family C1a
chr7_+_43690418 0.51 ENSMUST00000056329.6
kallikrein related-peptidase 14
chr3_+_127791374 0.51 ENSMUST00000171621.1
TRAF-interacting protein with forkhead-associated domain
chr10_-_64090265 0.49 ENSMUST00000105439.1
leucine rich repeat transmembrane neuronal 3
chr1_+_88138364 0.48 ENSMUST00000014263.4
UDP glucuronosyltransferase 1 family, polypeptide A6A
chr10_-_89621253 0.48 ENSMUST00000020102.7
solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 8
chr16_+_17276337 0.48 ENSMUST00000159065.1
ENSMUST00000159494.1
ENSMUST00000159811.1
transmembrane protein 191C
chr7_+_46841475 0.47 ENSMUST00000147535.1
lactate dehydrogenase A
chr2_+_69135799 0.47 ENSMUST00000041865.7
nitric oxide synthase trafficker
chr10_+_79854618 0.47 ENSMUST00000165704.1
polypyrimidine tract binding protein 1
chr2_+_144033059 0.47 ENSMUST00000037722.2
ENSMUST00000110032.1
barrier to autointegration factor 2
chr11_+_103116228 0.46 ENSMUST00000053063.5
hexamethylene bis-acetamide inducible 1
chr2_-_25500613 0.46 ENSMUST00000040042.4
complement component 8, gamma polypeptide
chr7_+_144175513 0.46 ENSMUST00000105900.1
SH3/ankyrin domain gene 2
chr10_+_42502030 0.46 ENSMUST00000105500.1
ENSMUST00000019939.5
sorting nexin 3
chr7_+_143005677 0.45 ENSMUST00000082008.5
ENSMUST00000105925.1
ENSMUST00000105924.1
tetraspanin 32
chr10_+_79854658 0.44 ENSMUST00000171599.1
ENSMUST00000095457.4
polypyrimidine tract binding protein 1
chr8_-_4105764 0.44 ENSMUST00000138439.1
ENSMUST00000145007.1
CD209f antigen
chr10_+_42502197 0.44 ENSMUST00000105499.1
sorting nexin 3
chr11_-_114934351 0.43 ENSMUST00000106581.1
ENSMUST00000074300.2
CD300 antigen like family member B
chr11_+_95843226 0.43 ENSMUST00000107709.1
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2
chr15_+_31568851 0.43 ENSMUST00000070918.6
carboxymethylenebutenolidase-like (Pseudomonas)
chrX_-_95658379 0.43 ENSMUST00000119640.1
zinc finger, C4H2 domain containing
chr5_-_24447587 0.42 ENSMUST00000127194.1
ENSMUST00000115033.1
ENSMUST00000123167.1
ENSMUST00000030799.8
transmembrane and ubiquitin-like domain containing 1
chr17_-_23684019 0.42 ENSMUST00000085989.5
claudin 9
chr2_+_126034967 0.42 ENSMUST00000110442.1
fibroblast growth factor 7
chr7_+_143005638 0.42 ENSMUST00000075172.5
ENSMUST00000105923.1
tetraspanin 32
chr4_-_49506538 0.42 ENSMUST00000043056.2
bile acid-Coenzyme A: amino acid N-acyltransferase
chr12_+_109743787 0.41 ENSMUST00000183068.1
miRNA containing gene
chr2_+_126034647 0.41 ENSMUST00000064794.7
fibroblast growth factor 7
chr1_-_120271074 0.41 ENSMUST00000112641.1
STEAP family member 3
chr7_+_30776394 0.41 ENSMUST00000041703.7
dermokine
chr19_-_41385070 0.41 ENSMUST00000059672.7
phosphoinositide-3-kinase adaptor protein 1
chr6_+_97807014 0.40 ENSMUST00000043637.7
microphthalmia-associated transcription factor
chr7_-_141172809 0.40 ENSMUST00000167493.1
ribonuclease/angiogenin inhibitor 1
chr11_-_120098673 0.40 ENSMUST00000093901.5
ENSMUST00000026442.4
ENSMUST00000106225.3
ENTH domain containing 2
chr11_+_119355551 0.39 ENSMUST00000050880.7
solute carrier family 26, member 11
chr16_-_34095983 0.39 ENSMUST00000114973.1
ENSMUST00000114964.1
kalirin, RhoGEF kinase
chr11_-_110095937 0.39 ENSMUST00000106664.3
ENSMUST00000046223.7
ENSMUST00000106662.1
ATP-binding cassette, sub-family A (ABC1), member 8a
chr13_+_58806564 0.38 ENSMUST00000109838.2
neurotrophic tyrosine kinase, receptor, type 2
chr3_+_132085281 0.38 ENSMUST00000029665.5
dickkopf homolog 2 (Xenopus laevis)
chr19_+_42147373 0.38 ENSMUST00000061111.9
MARVEL (membrane-associating) domain containing 1
chr18_-_32139570 0.38 ENSMUST00000171765.1
protein C
chr15_-_79804717 0.37 ENSMUST00000023057.8
neuronal pentraxin receptor
chr17_-_12675833 0.37 ENSMUST00000024596.8
solute carrier family 22 (organic cation transporter), member 1
chr9_+_5298517 0.37 ENSMUST00000027015.5
caspase 1
chr11_+_19924354 0.37 ENSMUST00000093299.6
sprouty-related, EVH1 domain containing 2
chr5_-_150665315 0.37 ENSMUST00000141857.1
NEDD4 binding protein 2-like 2
chr9_-_110989611 0.37 ENSMUST00000084922.5
receptor transporter protein 3
chr8_+_4134733 0.37 ENSMUST00000130372.1
CD209g antigen
chr10_-_82690608 0.37 ENSMUST00000065815.6
ENSMUST00000020485.3
glycosyltransferase 8 domain containing 2
chr11_+_103133333 0.37 ENSMUST00000124928.1
ENSMUST00000062530.4
hexamethylene bis-acetamide inducible 2
chr11_+_49609263 0.36 ENSMUST00000020617.2
FMS-like tyrosine kinase 4
chr10_+_77606571 0.36 ENSMUST00000099538.5
SMT3 suppressor of mif two 3 homolog 3 (yeast)
chr3_+_40708855 0.36 ENSMUST00000091184.6
solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 31
chr7_+_45405960 0.35 ENSMUST00000107774.1
potassium voltage-gated channel, shaker-related subfamily, member 7
chr6_-_129622685 0.35 ENSMUST00000032252.5
killer cell lectin-like receptor subfamily K, member 1
chr11_-_119355484 0.35 ENSMUST00000100172.2
ENSMUST00000005173.4
N-sulfoglucosamine sulfohydrolase (sulfamidase)
chr11_-_110095974 0.35 ENSMUST00000100287.2
ATP-binding cassette, sub-family A (ABC1), member 8a
chr1_-_139781236 0.35 ENSMUST00000027612.8
ENSMUST00000111989.2
ENSMUST00000111986.2
predicted gene 4788
chr19_+_43838803 0.34 ENSMUST00000099413.2
predicted gene 10768
chr4_-_43653560 0.34 ENSMUST00000107870.2
sperm associated antigen 8
chr18_+_20665250 0.34 ENSMUST00000075312.3
transthyretin
chr11_+_95842668 0.34 ENSMUST00000100532.3
ENSMUST00000036088.4
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2
chr7_-_29232478 0.34 ENSMUST00000085818.4
potassium inwardly-rectifying channel, subfamily K, member 6
chr3_-_59262825 0.34 ENSMUST00000050360.7
purinergic receptor P2Y, G-protein coupled 12
chr3_-_88552859 0.33 ENSMUST00000119002.1
ENSMUST00000029698.8
late endosomal/lysosomal adaptor, MAPK and MTOR activator 2
chr11_+_103133303 0.32 ENSMUST00000107037.1
hexamethylene bis-acetamide inducible 2
chr5_+_30013141 0.31 ENSMUST00000026845.7
interleukin 6
chr17_-_25792284 0.31 ENSMUST00000072735.7
family with sequence similarity 173, member A
chr12_+_88360801 0.31 ENSMUST00000166940.1
aarF domain containing kinase 1
chr7_-_30456849 0.31 ENSMUST00000169893.1
kin of IRRE like 2 (Drosophila)
chr4_-_96507386 0.31 ENSMUST00000124729.3
cytochrome P450, family 2, subfamily j, polypeptide 8
chr3_-_83841767 0.30 ENSMUST00000029623.9
toll-like receptor 2
chr6_-_131316398 0.30 ENSMUST00000121078.1
serine/threonine/tyrosine kinase 1
chr7_-_18616498 0.30 ENSMUST00000057810.6
pregnancy-specific glycoprotein 23
chr2_-_38287174 0.30 ENSMUST00000130472.1
DENN/MADD domain containing 1A
chr4_-_32602760 0.29 ENSMUST00000056517.2
gap junction protein, alpha 10
chr11_-_40692666 0.29 ENSMUST00000040167.4
methionine adenosyltransferase II, beta
chr3_+_145924303 0.29 ENSMUST00000029842.7
B cell leukemia/lymphoma 10
chr1_+_131638306 0.29 ENSMUST00000073350.6
cathepsin E
chr13_+_119623819 0.29 ENSMUST00000099241.2
chemokine (C-C motif) ligand 28
chr4_-_135353164 0.29 ENSMUST00000084846.5
ENSMUST00000136342.2
ENSMUST00000105861.1
serine/arginine repetitive matrix 1
chr11_+_61208621 0.29 ENSMUST00000108716.1
ENSMUST00000019246.3
aldehyde dehydrogenase family 3, subfamily A1
chr11_+_63132569 0.29 ENSMUST00000108701.1
peripheral myelin protein 22
chr18_-_36695925 0.29 ENSMUST00000115682.1
Riken cDNA E230025N22 gene
chr13_+_56438343 0.28 ENSMUST00000021971.5
solute carrier family 25, member 48
chr4_-_133339283 0.28 ENSMUST00000043305.7
WD and tetratricopeptide repeats 1
chr4_-_133339238 0.28 ENSMUST00000105906.1
WD and tetratricopeptide repeats 1
chr15_+_80623499 0.28 ENSMUST00000043149.7
GRB2-related adaptor protein 2
chr7_-_67222412 0.27 ENSMUST00000181631.1
RIKEN cDNA 1700112J16 gene
chr10_+_62133082 0.27 ENSMUST00000050103.1
neurogenin 3
chr9_+_123767211 0.27 ENSMUST00000166236.1
ENSMUST00000111454.2
ENSMUST00000168910.1
chemokine (C-C motif) receptor 9
chr14_+_41105359 0.27 ENSMUST00000047286.6
methionine adenosyltransferase I, alpha
chr7_-_99695809 0.27 ENSMUST00000107086.2
solute carrier organic anion transporter family, member 2b1
chr7_+_122671401 0.27 ENSMUST00000182095.1
calcium channel, voltage-dependent, gamma subunit 3
chr8_+_113643206 0.26 ENSMUST00000034219.4
ENSMUST00000095173.1
synaptonemal complex central element protein 1 like
chr4_+_141420757 0.26 ENSMUST00000102486.4
heat shock protein family, member 7 (cardiovascular)
chr5_-_137072254 0.26 ENSMUST00000077523.3
ENSMUST00000041388.4
serine (or cysteine) peptidase inhibitor, clade E, member 1
chr7_-_45211877 0.26 ENSMUST00000033057.7
dickkopf-like 1
chr15_+_76246747 0.26 ENSMUST00000023225.6
glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)
chr6_+_72355425 0.26 ENSMUST00000069695.2
ENSMUST00000132243.1
transmembrane protein 150A
chrX_-_155216444 0.26 ENSMUST00000026318.8
spermidine/spermine N1-acetyl transferase 1
chr12_+_88360535 0.25 ENSMUST00000101165.2
aarF domain containing kinase 1
chr19_-_45812291 0.25 ENSMUST00000086993.4
Kv channel-interacting protein 2
chr7_+_44012672 0.25 ENSMUST00000048945.4
kallikrein 1-related petidase b26
chr5_+_137350101 0.25 ENSMUST00000061244.8
Eph receptor B4
chr1_+_88070765 0.24 ENSMUST00000073772.4
UDP glucuronosyltransferase 1 family, polypeptide A9

Network of associatons between targets according to the STRING database.

First level regulatory network of Zbtb18

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.2 GO:1904219 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.4 1.3 GO:2000852 corticosterone secretion(GO:0035934) regulation of corticosterone secretion(GO:2000852)
0.3 0.9 GO:2000642 intralumenal vesicle formation(GO:0070676) negative regulation of early endosome to late endosome transport(GO:2000642)
0.3 0.8 GO:0061033 secretion by lung epithelial cell involved in lung growth(GO:0061033)
0.3 1.4 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.2 2.8 GO:0006707 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.2 0.7 GO:1901053 sarcosine metabolic process(GO:1901052) sarcosine catabolic process(GO:1901053)
0.2 0.6 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.2 0.6 GO:0032097 positive regulation of response to food(GO:0032097) positive regulation of appetite(GO:0032100) hindgut contraction(GO:0043133) regulation of hindgut contraction(GO:0043134) positive regulation of eating behavior(GO:1904000) positive regulation of small intestine smooth muscle contraction(GO:1904349)
0.2 0.6 GO:0040030 regulation of molecular function, epigenetic(GO:0040030)
0.2 0.6 GO:0001788 antibody-dependent cellular cytotoxicity(GO:0001788)
0.2 0.6 GO:0071918 urea transmembrane transport(GO:0071918)
0.2 1.1 GO:0002317 plasma cell differentiation(GO:0002317)
0.2 0.5 GO:0046462 monoacylglycerol metabolic process(GO:0046462)
0.2 4.0 GO:0001967 suckling behavior(GO:0001967)
0.2 0.5 GO:0032918 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.2 0.6 GO:0061113 pancreas morphogenesis(GO:0061113)
0.1 0.6 GO:0034769 basement membrane disassembly(GO:0034769)
0.1 1.0 GO:1903142 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.1 0.6 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.1 2.9 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.1 0.5 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.1 1.9 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.1 0.6 GO:0060697 positive regulation of phospholipid catabolic process(GO:0060697)
0.1 0.4 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.1 0.6 GO:0038094 Fc-gamma receptor signaling pathway(GO:0038094)
0.1 1.3 GO:0030885 regulation of myeloid dendritic cell activation(GO:0030885)
0.1 0.4 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.1 0.6 GO:1902167 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902167)
0.1 0.3 GO:0002752 cell surface pattern recognition receptor signaling pathway(GO:0002752)
0.1 0.8 GO:0070447 positive regulation of oligodendrocyte progenitor proliferation(GO:0070447)
0.1 2.2 GO:0061436 establishment of skin barrier(GO:0061436)
0.1 3.8 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.1 0.4 GO:1903575 cornified envelope assembly(GO:1903575)
0.1 0.7 GO:0030382 sperm mitochondrion organization(GO:0030382)
0.1 0.3 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
0.1 0.3 GO:2000314 fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:0060825) regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000313) negative regulation of fibroblast growth factor receptor signaling pathway involved in neural plate anterior/posterior pattern formation(GO:2000314)
0.1 0.3 GO:0019442 tryptophan catabolic process to acetyl-CoA(GO:0019442)
0.1 0.5 GO:0019244 lactate biosynthetic process from pyruvate(GO:0019244)
0.1 0.3 GO:0071718 sodium-independent icosanoid transport(GO:0071718)
0.1 0.7 GO:0045409 negative regulation of interleukin-6 biosynthetic process(GO:0045409)
0.1 0.4 GO:0010248 establishment or maintenance of transmembrane electrochemical gradient(GO:0010248)
0.1 0.4 GO:1904451 regulation of hydrogen:potassium-exchanging ATPase activity(GO:1904451) positive regulation of hydrogen:potassium-exchanging ATPase activity(GO:1904453)
0.1 0.4 GO:1902037 negative regulation of hematopoietic stem cell differentiation(GO:1902037)
0.1 0.2 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760)
0.1 0.3 GO:0002305 gamma-delta intraepithelial T cell differentiation(GO:0002304) CD8-positive, gamma-delta intraepithelial T cell differentiation(GO:0002305)
0.1 0.3 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.1 0.8 GO:0071231 neural crest cell migration involved in heart formation(GO:0003147) anterior neural tube closure(GO:0061713) cellular response to folic acid(GO:0071231)
0.1 0.6 GO:1903012 positive regulation of bone development(GO:1903012)
0.1 0.3 GO:1904139 microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.1 0.9 GO:0070166 enamel mineralization(GO:0070166)
0.1 0.9 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.1 0.3 GO:0002905 mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906)
0.1 2.1 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.1 0.7 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.1 0.2 GO:0045404 positive regulation of interleukin-4 biosynthetic process(GO:0045404)
0.1 0.8 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.1 0.3 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.1 0.5 GO:0002035 brain renin-angiotensin system(GO:0002035)
0.1 0.7 GO:0052696 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.1 0.9 GO:0035814 negative regulation of renal sodium excretion(GO:0035814)
0.1 0.5 GO:0007320 insemination(GO:0007320)
0.1 0.1 GO:1904444 regulation of establishment of Sertoli cell barrier(GO:1904444)
0.1 0.3 GO:0060075 regulation of resting membrane potential(GO:0060075)
0.1 0.4 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.1 0.3 GO:0034154 toll-like receptor 7 signaling pathway(GO:0034154)
0.1 0.1 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.0 0.2 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.0 0.3 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 0.2 GO:2000525 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.0 0.2 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.0 0.1 GO:0031448 regulation of fast-twitch skeletal muscle fiber contraction(GO:0031446) positive regulation of fast-twitch skeletal muscle fiber contraction(GO:0031448)
0.0 0.4 GO:0046958 nonassociative learning(GO:0046958) habituation(GO:0046959) negative regulation of growth hormone secretion(GO:0060125) behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.0 0.2 GO:0035524 regulation of amino acid import(GO:0010958) proline transmembrane transport(GO:0035524) glycine import(GO:0036233)
0.0 0.3 GO:0070327 thyroid hormone transport(GO:0070327)
0.0 1.2 GO:0032094 response to food(GO:0032094)
0.0 0.4 GO:0031547 brain-derived neurotrophic factor receptor signaling pathway(GO:0031547)
0.0 0.2 GO:0042360 vitamin E metabolic process(GO:0042360)
0.0 0.2 GO:0003365 establishment of cell polarity involved in ameboidal cell migration(GO:0003365)
0.0 0.1 GO:1901993 meiotic cell cycle phase transition(GO:0044771) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.0 0.7 GO:0002523 leukocyte migration involved in inflammatory response(GO:0002523)
0.0 0.5 GO:0070995 NADPH oxidation(GO:0070995)
0.0 0.4 GO:0044336 canonical Wnt signaling pathway involved in negative regulation of apoptotic process(GO:0044336)
0.0 0.2 GO:0035234 ectopic germ cell programmed cell death(GO:0035234)
0.0 0.5 GO:1902004 positive regulation of beta-amyloid formation(GO:1902004)
0.0 1.4 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 0.1 GO:0010536 positive regulation of activation of Janus kinase activity(GO:0010536)
0.0 0.2 GO:0072014 proximal tubule development(GO:0072014)
0.0 0.1 GO:0003274 tolerance induction to self antigen(GO:0002513) endocardial cushion fusion(GO:0003274) positive regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000563)
0.0 0.1 GO:0080144 amino acid homeostasis(GO:0080144)
0.0 0.1 GO:0098528 skeletal muscle fiber differentiation(GO:0098528)
0.0 0.6 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.0 0.5 GO:0043517 positive regulation of DNA damage response, signal transduction by p53 class mediator(GO:0043517)
0.0 0.6 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.4 GO:0006544 glycine metabolic process(GO:0006544) taurine metabolic process(GO:0019530)
0.0 1.1 GO:1904030 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
0.0 0.6 GO:0039694 viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)
0.0 0.3 GO:0060290 transdifferentiation(GO:0060290)
0.0 0.4 GO:0090037 positive regulation of protein kinase C signaling(GO:0090037)
0.0 0.1 GO:0060594 mammary gland specification(GO:0060594)
0.0 0.4 GO:0097264 self proteolysis(GO:0097264)
0.0 0.2 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.0 0.3 GO:0098762 meiotic prophase I(GO:0007128) prophase(GO:0051324) meiotic cell cycle phase(GO:0098762) meiosis I cell cycle phase(GO:0098764)
0.0 0.2 GO:0035931 mineralocorticoid secretion(GO:0035931) aldosterone secretion(GO:0035932) regulation of mineralocorticoid secretion(GO:2000855) positive regulation of mineralocorticoid secretion(GO:2000857) regulation of aldosterone secretion(GO:2000858) positive regulation of aldosterone secretion(GO:2000860)
0.0 0.3 GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.0 0.1 GO:0032962 positive regulation of inositol trisphosphate biosynthetic process(GO:0032962)
0.0 0.5 GO:0051968 positive regulation of synaptic transmission, glutamatergic(GO:0051968) vocalization behavior(GO:0071625)
0.0 0.3 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 0.4 GO:2000060 positive regulation of protein ubiquitination involved in ubiquitin-dependent protein catabolic process(GO:2000060)
0.0 0.2 GO:0048664 neuron fate determination(GO:0048664)
0.0 0.5 GO:0048148 behavioral response to cocaine(GO:0048148)
0.0 0.4 GO:0008272 sulfate transport(GO:0008272)
0.0 2.5 GO:0007586 digestion(GO:0007586)
0.0 0.3 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.1 GO:0042732 D-xylose metabolic process(GO:0042732)
0.0 0.4 GO:0033005 positive regulation of mast cell activation(GO:0033005)
0.0 0.1 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.0 0.5 GO:0015813 L-glutamate transport(GO:0015813)
0.0 0.8 GO:0010644 cell communication by electrical coupling(GO:0010644)
0.0 0.1 GO:0060754 positive regulation of mast cell chemotaxis(GO:0060754)
0.0 0.3 GO:0032060 bleb assembly(GO:0032060)
0.0 0.9 GO:0030199 collagen fibril organization(GO:0030199)
0.0 0.9 GO:0050873 brown fat cell differentiation(GO:0050873)
0.0 0.2 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0 0.1 GO:0097531 mast cell chemotaxis(GO:0002551) mast cell migration(GO:0097531)
0.0 0.3 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.1 GO:0016576 histone dephosphorylation(GO:0016576)
0.0 0.3 GO:0050962 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.1 GO:0019364 pyridine nucleotide catabolic process(GO:0019364)
0.0 0.2 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.0 0.1 GO:0015808 L-alanine transport(GO:0015808)
0.0 0.6 GO:0010718 positive regulation of epithelial to mesenchymal transition(GO:0010718)
0.0 0.1 GO:0018343 protein farnesylation(GO:0018343)
0.0 0.0 GO:2000872 positive regulation of female gonad development(GO:2000196) positive regulation of progesterone secretion(GO:2000872)
0.0 0.1 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.0 0.2 GO:0061525 hindgut development(GO:0061525)
0.0 0.1 GO:0009407 toxin catabolic process(GO:0009407) secondary metabolite catabolic process(GO:0090487)
0.0 0.2 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.0 0.7 GO:0030819 positive regulation of cAMP biosynthetic process(GO:0030819)
0.0 0.1 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.3 GO:0006691 leukotriene metabolic process(GO:0006691)
0.0 0.6 GO:2000649 regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.0 0.2 GO:0043304 regulation of mast cell activation involved in immune response(GO:0033006) regulation of mast cell degranulation(GO:0043304)
0.0 0.1 GO:0048563 post-embryonic organ morphogenesis(GO:0048563)
0.0 0.4 GO:0046854 phosphatidylinositol phosphorylation(GO:0046854)
0.0 0.0 GO:0097325 melanocyte proliferation(GO:0097325)
0.0 0.2 GO:0045671 negative regulation of osteoclast differentiation(GO:0045671)
0.0 0.1 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.2 GO:0016926 protein desumoylation(GO:0016926)
0.0 0.1 GO:0046548 retinal rod cell development(GO:0046548)
0.0 0.0 GO:0060452 positive regulation of cardiac muscle contraction(GO:0060452) positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.0 0.0 GO:0009080 alanine catabolic process(GO:0006524) pyruvate family amino acid catabolic process(GO:0009080) D-amino acid catabolic process(GO:0019478)
0.0 0.1 GO:0070813 hydrogen sulfide metabolic process(GO:0070813)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0070442 integrin alphaIIb-beta3 complex(GO:0070442)
0.1 0.6 GO:0034687 integrin alphaL-beta2 complex(GO:0034687)
0.1 0.4 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.1 0.6 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.1 0.6 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.1 0.5 GO:0097450 astrocyte end-foot(GO:0097450)
0.1 1.4 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.1 0.3 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.1 0.4 GO:0097169 AIM2 inflammasome complex(GO:0097169)
0.1 0.4 GO:1990795 lateral part of cell(GO:0097574) basolateral part of cell(GO:1990794) rod bipolar cell terminal bouton(GO:1990795)
0.1 0.9 GO:0031983 vesicle lumen(GO:0031983)
0.1 0.3 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.1 0.7 GO:0097227 sperm annulus(GO:0097227)
0.1 0.8 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.1 3.3 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.1 0.6 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.1 0.9 GO:0032009 early phagosome(GO:0032009)
0.1 0.5 GO:0005579 membrane attack complex(GO:0005579)
0.1 0.3 GO:0071986 Ragulator complex(GO:0071986)
0.1 1.1 GO:0005922 connexon complex(GO:0005922)
0.1 0.3 GO:0042583 chromaffin granule(GO:0042583)
0.0 0.5 GO:0005883 neurofilament(GO:0005883)
0.0 0.8 GO:0035102 PRC1 complex(GO:0035102)
0.0 1.2 GO:0042588 zymogen granule(GO:0042588)
0.0 0.2 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.0 0.3 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.9 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.2 GO:0035976 AP1 complex(GO:0035976)
0.0 0.1 GO:0035841 new growing cell tip(GO:0035841)
0.0 0.5 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.1 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.0 0.5 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 3.3 GO:0072562 blood microparticle(GO:0072562)
0.0 0.1 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.0 0.1 GO:0005607 laminin-2 complex(GO:0005607)
0.0 0.1 GO:0002081 outer acrosomal membrane(GO:0002081)
0.0 0.6 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.1 GO:0072557 IPAF inflammasome complex(GO:0072557)
0.0 0.1 GO:1990923 PET complex(GO:1990923)
0.0 0.0 GO:0043202 lysosomal lumen(GO:0043202)
0.0 0.3 GO:0043218 compact myelin(GO:0043218)
0.0 0.3 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.6 GO:0005771 multivesicular body(GO:0005771)
0.0 0.1 GO:0033269 internode region of axon(GO:0033269)
0.0 0.1 GO:1990246 uniplex complex(GO:1990246)
0.0 0.2 GO:0002177 manchette(GO:0002177)
0.0 0.1 GO:0031673 H zone(GO:0031673)
0.0 0.2 GO:0036157 outer dynein arm(GO:0036157)
0.0 20.2 GO:0005615 extracellular space(GO:0005615)
0.0 0.0 GO:0098559 cytoplasmic side of early endosome membrane(GO:0098559)
0.0 0.5 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 1.7 GO:0005923 bicellular tight junction(GO:0005923)
0.0 0.1 GO:0030688 preribosome, small subunit precursor(GO:0030688)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0004771 sterol esterase activity(GO:0004771)
0.4 1.1 GO:0048030 disaccharide binding(GO:0048030)
0.3 1.2 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.2 0.7 GO:0008480 sarcosine dehydrogenase activity(GO:0008480) oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997)
0.2 0.9 GO:0033765 steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765)
0.2 3.2 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.2 0.6 GO:0046911 metal chelating activity(GO:0046911)
0.2 0.6 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.2 1.8 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.2 0.8 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.2 0.5 GO:0004145 diamine N-acetyltransferase activity(GO:0004145)
0.2 0.9 GO:0001069 regulatory region RNA binding(GO:0001069)
0.1 0.6 GO:0030369 ICAM-3 receptor activity(GO:0030369)
0.1 1.1 GO:0097322 7SK snRNA binding(GO:0097322)
0.1 0.5 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.1 0.8 GO:1903763 gap junction channel activity involved in cell communication by electrical coupling(GO:1903763)
0.1 0.4 GO:0005333 norepinephrine transmembrane transporter activity(GO:0005333)
0.1 0.5 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.1 0.6 GO:0031781 melanocortin receptor binding(GO:0031779) type 3 melanocortin receptor binding(GO:0031781) type 4 melanocortin receptor binding(GO:0031782)
0.1 0.9 GO:0050786 RAGE receptor binding(GO:0050786)
0.1 0.6 GO:0019770 IgG receptor activity(GO:0019770)
0.1 2.6 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 0.8 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.1 1.0 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.1 0.3 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.1 0.3 GO:0005302 hydrogen:amino acid symporter activity(GO:0005280) L-tyrosine transmembrane transporter activity(GO:0005302)
0.1 0.4 GO:0001847 opsonin receptor activity(GO:0001847)
0.1 1.4 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.1 0.6 GO:0015091 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.1 0.9 GO:0008430 selenium binding(GO:0008430)
0.1 0.5 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 0.6 GO:0015204 urea transmembrane transporter activity(GO:0015204)
0.1 0.2 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
0.1 0.4 GO:0070012 oligopeptidase activity(GO:0070012)
0.1 0.5 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.1 0.4 GO:0031849 olfactory receptor binding(GO:0031849)
0.1 0.6 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1 0.3 GO:0016822 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.1 0.8 GO:0051870 methotrexate binding(GO:0051870)
0.1 0.2 GO:0008431 vitamin E binding(GO:0008431)
0.1 10.5 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.1 0.4 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.1 2.1 GO:0008009 chemokine activity(GO:0008009)
0.1 0.4 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.1 2.0 GO:0008236 serine-type peptidase activity(GO:0008236)
0.1 0.8 GO:0097153 cysteine-type endopeptidase activity involved in apoptotic process(GO:0097153)
0.1 1.3 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.1 0.3 GO:0071723 lipopeptide binding(GO:0071723)
0.1 0.4 GO:0008428 ribonuclease inhibitor activity(GO:0008428)
0.0 0.2 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.4 GO:0039706 co-receptor binding(GO:0039706)
0.0 0.8 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.6 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.0 2.1 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 0.3 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.0 0.6 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.1 GO:0052596 tryptamine:oxygen oxidoreductase (deaminating) activity(GO:0052593) aminoacetone:oxygen oxidoreductase(deaminating) activity(GO:0052594) aliphatic-amine oxidase activity(GO:0052595) phenethylamine:oxygen oxidoreductase (deaminating) activity(GO:0052596)
0.0 0.3 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.0 0.6 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.7 GO:0005313 L-glutamate transmembrane transporter activity(GO:0005313)
0.0 0.3 GO:0070324 thyroid hormone binding(GO:0070324)
0.0 0.4 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.5 GO:0019841 retinol binding(GO:0019841)
0.0 0.4 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.1 GO:0001962 alpha-1,3-galactosyltransferase activity(GO:0001962)
0.0 0.3 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.3 GO:0043237 laminin-1 binding(GO:0043237)
0.0 1.0 GO:0019789 SUMO transferase activity(GO:0019789)
0.0 0.9 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.1 GO:0015189 L-lysine transmembrane transporter activity(GO:0015189)
0.0 0.4 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.4 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.1 GO:0019959 interleukin-8 binding(GO:0019959)
0.0 0.1 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 0.1 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.0 0.2 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.0 0.1 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.0 0.8 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.3 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656) peptidase activator activity involved in apoptotic process(GO:0016505)
0.0 0.1 GO:0030613 oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor(GO:0016672) oxidoreductase activity, acting on phosphorus or arsenic in donors(GO:0030613) oxidoreductase activity, acting on phosphorus or arsenic in donors, disulfide as acceptor(GO:0030614) glutathione dehydrogenase (ascorbate) activity(GO:0045174) methylarsonate reductase activity(GO:0050610)
0.0 0.4 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.0 0.2 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.0 0.3 GO:0005549 odorant binding(GO:0005549)
0.0 0.4 GO:0001618 virus receptor activity(GO:0001618)
0.0 6.2 GO:0030246 carbohydrate binding(GO:0030246)
0.0 0.7 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.1 GO:0018685 alkane 1-monooxygenase activity(GO:0018685)
0.0 0.4 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0 0.1 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.0 0.5 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.2 GO:0015250 water transmembrane transporter activity(GO:0005372) water channel activity(GO:0015250)
0.0 0.5 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.1 GO:0052723 inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.0 0.6 GO:0005227 calcium activated cation channel activity(GO:0005227)
0.0 0.3 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.0 0.1 GO:0089720 caspase binding(GO:0089720)
0.0 0.4 GO:0031005 filamin binding(GO:0031005)
0.0 2.0 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.2 GO:0005003 ephrin receptor activity(GO:0005003)
0.0 0.2 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.1 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.0 0.3 GO:0004190 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.8 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.1 GO:0102337 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.0 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
0.0 0.4 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.6 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.2 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.0 0.1 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.0 0.3 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 0.5 GO:0050699 WW domain binding(GO:0050699)
0.0 0.1 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0 0.1 GO:0019869 chloride channel inhibitor activity(GO:0019869)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.8 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.5 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 1.6 PID IL23 PATHWAY IL23-mediated signaling events
0.0 1.0 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.6 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 6.5 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.4 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 1.5 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 0.6 PID S1P S1P2 PATHWAY S1P2 pathway
0.0 0.6 PID CONE PATHWAY Visual signal transduction: Cones
0.0 1.0 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.3 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.0 0.4 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.6 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.0 0.4 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 1.7 PID CMYB PATHWAY C-MYB transcription factor network
0.0 0.3 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.5 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.7 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.4 PID SHP2 PATHWAY SHP2 signaling
0.0 0.5 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.5 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.3 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 2.9 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 0.4 PID BCR 5PATHWAY BCR signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.7 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.1 1.8 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 0.9 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.1 0.4 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.1 1.1 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.1 1.3 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 0.3 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 1.9 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.8 REACTOME ACTIVATED POINT MUTANTS OF FGFR2 Genes involved in Activated point mutants of FGFR2
0.0 1.7 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.9 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.4 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.4 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 1.2 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0 1.9 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.3 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.4 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.3 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.3 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 1.2 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.0 0.3 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.6 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.2 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.6 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.0 0.5 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.0 0.6 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 0.3 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.8 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.4 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 0.5 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.0 0.7 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.5 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.0 0.2 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.2 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.4 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 0.2 REACTOME ACYL CHAIN REMODELLING OF PS Genes involved in Acyl chain remodelling of PS
0.0 1.1 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.1 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.2 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.3 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.4 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling