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2D miR_HR1_12

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Results for Tcf7l1

Z-value: 0.69

Motif logo

Transcription factors associated with Tcf7l1

Gene Symbol Gene ID Gene Info
ENSMUSG00000055799.7 transcription factor 7 like 1 (T cell specific, HMG box)

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Tcf7l1mm10_v2_chr6_-_72789240_72789262-0.565.7e-02Click!

Activity profile of Tcf7l1 motif

Sorted Z-values of Tcf7l1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_136467958 1.30 ENSMUST00000047817.6
kinesin family member 14
chr5_-_148392810 1.13 ENSMUST00000138257.1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr19_-_41802028 1.09 ENSMUST00000026150.8
ENSMUST00000177495.1
ENSMUST00000163265.1
Rho GTPase activating protein 19
chr11_-_87108656 1.00 ENSMUST00000051395.8
proline rich 11
chr6_-_148944750 0.92 ENSMUST00000111562.1
ENSMUST00000081956.5
family with sequence similarity 60, member A
chr4_+_107367757 0.88 ENSMUST00000139560.1
NDC1 transmembrane nucleoporin
chr1_+_158362261 0.87 ENSMUST00000046110.9
astrotactin 1
chr2_+_173022360 0.79 ENSMUST00000173997.1
RNA binding motif protein 38
chr12_-_76795489 0.78 ENSMUST00000082431.3
glutathione peroxidase 2
chr2_+_157560078 0.77 ENSMUST00000153739.2
ENSMUST00000173595.1
ENSMUST00000109526.1
ENSMUST00000173839.1
ENSMUST00000173041.1
ENSMUST00000173793.1
ENSMUST00000172487.1
ENSMUST00000088484.5
neuronatin
chr4_-_91376433 0.74 ENSMUST00000107109.2
ENSMUST00000107111.2
ENSMUST00000107120.1
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr2_+_153031852 0.71 ENSMUST00000037235.6
X Kell blood group precursor related family member 7 homolog
chrX_-_48034842 0.66 ENSMUST00000039026.7
apelin
chr1_-_64122256 0.63 ENSMUST00000135075.1
Kruppel-like factor 7 (ubiquitous)
chr6_-_99726392 0.63 ENSMUST00000032152.8
ENSMUST00000101120.4
ENSMUST00000008273.6
prokineticin 2
chr2_+_173021902 0.60 ENSMUST00000029014.9
RNA binding motif protein 38
chr1_+_158362330 0.60 ENSMUST00000170718.1
astrotactin 1
chr2_+_121357714 0.60 ENSMUST00000125812.1
ENSMUST00000078222.2
ENSMUST00000125221.1
ENSMUST00000150271.1
creatine kinase, mitochondrial 1, ubiquitous
chr3_+_122895072 0.60 ENSMUST00000023820.5
fatty acid binding protein 2, intestinal
chr1_-_12991109 0.58 ENSMUST00000115403.2
ENSMUST00000115402.1
solute carrier organic anion transporter family, member 5A1
chr4_-_91376490 0.53 ENSMUST00000107124.3
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chrX_+_71556874 0.52 ENSMUST00000123100.1
high mobility group box 3
chr13_-_103096818 0.51 ENSMUST00000166336.1
microtubule associated serine/threonine kinase family member 4
chr17_+_7925990 0.51 ENSMUST00000036370.7
T cell activation Rho GTPase activating protein
chr10_-_117063764 0.50 ENSMUST00000047672.7
chaperonin containing Tcp1, subunit 2 (beta)
chr15_-_98953541 0.49 ENSMUST00000097014.5
tubulin, alpha 1A
chr4_+_11758147 0.48 ENSMUST00000029871.5
ENSMUST00000108303.1
cadherin 17
chr12_-_54986363 0.48 ENSMUST00000173433.1
ENSMUST00000173803.1
bromodomain adjacent to zinc finger domain 1A
predicted gene 20403
chr5_+_37242025 0.48 ENSMUST00000114158.2
collapsin response mediator protein 1
chr12_+_84409039 0.47 ENSMUST00000081828.6
coiled-coil domain containing 176
chr9_+_110132015 0.47 ENSMUST00000088716.5
ENSMUST00000111969.1
ENSMUST00000035057.7
ENSMUST00000111966.1
ENSMUST00000111968.1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1
chr18_+_21072329 0.46 ENSMUST00000082235.4
meprin 1 beta
chr7_-_118129567 0.46 ENSMUST00000032888.7
ADP-ribosylation factor-like 6 interacting protein 1
chr14_-_98169542 0.44 ENSMUST00000069334.7
ENSMUST00000071533.6
dachshund 1 (Drosophila)
chr18_+_4921662 0.43 ENSMUST00000143254.1
supervillin
chr14_+_101840501 0.43 ENSMUST00000159026.1
LIM domain only 7
chr19_-_37330613 0.43 ENSMUST00000131070.1
insulin degrading enzyme
chr11_+_108921648 0.42 ENSMUST00000144511.1
axin2
chr12_-_98737405 0.41 ENSMUST00000170188.1
protein tyrosine phosphatase, non-receptor type 21
chr11_-_78497734 0.40 ENSMUST00000061174.6
sterile alpha and HEAT/Armadillo motif containing 1
chr1_-_105659008 0.40 ENSMUST00000070699.8
phosphatidylinositol glycan anchor biosynthesis, class N
chr14_+_119138415 0.40 ENSMUST00000065904.3
heparan sulfate 6-O-sulfotransferase 3
chr19_-_46327121 0.40 ENSMUST00000041391.4
ENSMUST00000096029.5
pleckstrin and Sec7 domain containing
chr14_+_50924968 0.39 ENSMUST00000049411.5
ENSMUST00000136753.1
ENSMUST00000154288.1
apurinic/apyrimidinic endonuclease 1
chr14_-_31019055 0.38 ENSMUST00000037739.6
guanine nucleotide binding protein-like 3 (nucleolar)
chr8_+_70493156 0.38 ENSMUST00000008032.7
cytokine receptor-like factor 1
chr6_-_47594967 0.38 ENSMUST00000081721.6
ENSMUST00000114618.1
ENSMUST00000114616.1
enhancer of zeste homolog 2 (Drosophila)
chr1_+_59482133 0.37 ENSMUST00000114246.2
ENSMUST00000037105.6
frizzled homolog 7 (Drosophila)
chr9_+_119402444 0.36 ENSMUST00000035093.8
ENSMUST00000165044.1
activin receptor IIB
chr3_-_50443603 0.36 ENSMUST00000029297.4
solute carrier family 7 (cationic amino acid transporter, y+ system), member 11
chr1_-_86111970 0.34 ENSMUST00000027431.6
5-hydroxytryptamine (serotonin) receptor 2B
chr8_-_40511298 0.33 ENSMUST00000149992.1
CCR4-NOT transcription complex, subunit 7
chr2_-_65567505 0.33 ENSMUST00000100069.2
sodium channel, voltage-gated, type III, alpha
chr17_-_46202576 0.33 ENSMUST00000024749.7
polymerase (DNA directed), eta (RAD 30 related)
chr4_+_85205120 0.32 ENSMUST00000107188.3
SH3-domain GRB2-like 2
chr8_+_79028587 0.32 ENSMUST00000119254.1
zinc finger protein 827
chr17_-_70851189 0.31 ENSMUST00000059775.8
TGFB-induced factor homeobox 1
chr3_-_122619442 0.31 ENSMUST00000162947.1
formin binding protein 1-like
chr2_-_65567465 0.31 ENSMUST00000066432.5
sodium channel, voltage-gated, type III, alpha
chr4_+_127172866 0.31 ENSMUST00000106094.2
discs, large (Drosophila) homolog-associated protein 3
chr6_+_54039558 0.30 ENSMUST00000046856.7
chimerin (chimaerin) 2
chr15_-_50890396 0.30 ENSMUST00000185183.1
trichorhinophalangeal syndrome I (human)
chrX_+_151198078 0.30 ENSMUST00000184730.1
ENSMUST00000184392.1
ENSMUST00000096285.4
WNK lysine deficient protein kinase 3
chr5_+_65131184 0.30 ENSMUST00000031089.5
ENSMUST00000101191.3
kelch-like 5
chr7_+_100493795 0.30 ENSMUST00000129324.1
uncoupling protein 2 (mitochondrial, proton carrier)
chr1_+_165788746 0.30 ENSMUST00000161559.2
CD247 antigen
chr8_-_84773381 0.29 ENSMUST00000109764.1
nuclear factor I/X
chr14_+_101729907 0.29 ENSMUST00000100337.3
LIM domain only 7
chr19_-_46338632 0.29 ENSMUST00000051234.8
ENSMUST00000167861.1
CUE domain containing 2
chr11_-_78497458 0.29 ENSMUST00000108287.3
sterile alpha and HEAT/Armadillo motif containing 1
chr4_+_85205417 0.29 ENSMUST00000030212.8
ENSMUST00000107189.1
ENSMUST00000107184.1
SH3-domain GRB2-like 2
chr12_-_84408991 0.28 ENSMUST00000120942.1
ENSMUST00000110272.2
ectonucleoside triphosphate diphosphohydrolase 5
chrX_-_57392962 0.28 ENSMUST00000114730.1
RNA binding motif protein, X chromosome
chrX_-_57393020 0.27 ENSMUST00000143310.1
ENSMUST00000098470.2
ENSMUST00000114726.1
RNA binding motif protein, X chromosome
chr5_+_148265307 0.26 ENSMUST00000110514.1
microtubule associated tumor suppressor candidate 2
chr1_+_165788681 0.26 ENSMUST00000161971.1
ENSMUST00000178336.1
ENSMUST00000005907.5
ENSMUST00000027849.4
CD247 antigen
chr8_-_40511663 0.25 ENSMUST00000135269.1
ENSMUST00000034012.3
CCR4-NOT transcription complex, subunit 7
chr7_-_83884289 0.25 ENSMUST00000094216.3
mesoderm development candidate 1
chr4_-_34882919 0.25 ENSMUST00000098163.2
ENSMUST00000047950.5
zinc finger protein 292
chr4_+_107802277 0.25 ENSMUST00000106733.2
ENSMUST00000030356.3
ENSMUST00000106732.2
ENSMUST00000126573.1
low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
chr9_+_98490522 0.25 ENSMUST00000035029.2
retinol binding protein 2, cellular
chr9_-_65021645 0.24 ENSMUST00000036615.5
protein tyrosine phosphatase-like A domain containing 1
chr10_+_80300997 0.24 ENSMUST00000140828.1
ENSMUST00000138909.1
adenomatosis polyposis coli 2
chr2_-_65529275 0.24 ENSMUST00000126837.1
sodium channel, voltage-gated, type III, alpha
chr5_+_148265202 0.23 ENSMUST00000110515.2
microtubule associated tumor suppressor candidate 2
chr9_+_35423582 0.23 ENSMUST00000154652.1
cell adhesion molecule-related/down-regulated by oncogenes
chr1_+_110099295 0.23 ENSMUST00000134301.1
cadherin 7, type 2
chr4_+_48585135 0.23 ENSMUST00000030032.6
transmembrane protein with EGF-like and two follistatin-like domains 1
chr1_+_132008285 0.23 ENSMUST00000146432.1
ELK4, member of ETS oncogene family
chr11_-_48946148 0.23 ENSMUST00000104958.1
protease (prosome, macropain) activator subunit 2B
chr10_+_60106452 0.22 ENSMUST00000165024.2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan 2
chr2_+_138278481 0.22 ENSMUST00000075410.4
BTB (POZ) domain containing 3
chr4_+_108479081 0.22 ENSMUST00000155068.1
zinc finger, CCHC domain containing 11
chr4_+_127021311 0.22 ENSMUST00000030623.7
splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated)
chr2_-_20968526 0.22 ENSMUST00000141298.2
ENSMUST00000125783.2
Rho GTPase activating protein 21
chr1_-_183147461 0.22 ENSMUST00000171366.1
dispatched homolog 1 (Drosophila)
chr2_+_35582829 0.22 ENSMUST00000135741.1
disabled 2 interacting protein
chr10_-_13388830 0.22 ENSMUST00000079698.5
phosphatase and actin regulator 2
chr12_-_24096968 0.22 ENSMUST00000101538.3
RIKEN cDNA 9030624G23 gene
chr19_-_5729618 0.21 ENSMUST00000116558.2
ENSMUST00000099955.3
ENSMUST00000161368.1
family with sequence similarity 89, member B
chr10_-_86011833 0.21 ENSMUST00000105304.1
ENSMUST00000061699.5
BPI fold containing family C
chr8_-_85067982 0.21 ENSMUST00000177563.1
predicted gene 5741
chr12_+_84996309 0.20 ENSMUST00000168977.1
ENSMUST00000021670.8
YLP motif containing 1
chr1_-_153487639 0.20 ENSMUST00000042141.5
DEAH (Asp-Glu-Ala-His) box polypeptide 9
chr5_+_148265265 0.20 ENSMUST00000071878.5
microtubule associated tumor suppressor candidate 2
chr17_-_6961156 0.20 ENSMUST00000063683.6
T cell activation GTPase activating protein 1
chr14_+_58076507 0.20 ENSMUST00000166770.1
fibroblast growth factor 9
chr13_-_102905740 0.19 ENSMUST00000167462.1
microtubule associated serine/threonine kinase family member 4
chr19_+_8839298 0.19 ENSMUST00000160556.1
Bernardinelli-Seip congenital lipodystrophy 2 homolog (human)
chr3_-_144932523 0.19 ENSMUST00000098549.3
expressed sequence AI747448
chr1_+_132191436 0.19 ENSMUST00000112357.2
LEM domain containing 1
chr1_+_131153175 0.19 ENSMUST00000112446.2
ENSMUST00000068805.7
ENSMUST00000068791.4
eukaryotic translation initiation factor 2D
chr10_-_22731336 0.19 ENSMUST00000127698.1
TATA box binding protein-like 1
chr7_+_126760591 0.18 ENSMUST00000091328.2
mitogen-activated protein kinase 3
chr12_+_24498570 0.18 ENSMUST00000075954.7
TATA box binding protein (Tbp)-associated factor, RNA polymerase I, B
chr5_-_122050102 0.18 ENSMUST00000154139.1
cut-like homeobox 2
chr18_-_12819842 0.18 ENSMUST00000119043.1
oxysterol binding protein-like 1A
chrX_-_143933089 0.18 ENSMUST00000087313.3
doublecortin
chr1_+_181150926 0.17 ENSMUST00000134115.1
ENSMUST00000111059.1
cornichon homolog 4 (Drosophila)
chr2_-_114201416 0.17 ENSMUST00000050668.3
zinc finger protein 770
chr4_-_94650092 0.17 ENSMUST00000107101.1
leucine rich repeat containing 19
chr12_+_84996487 0.17 ENSMUST00000101202.3
YLP motif containing 1
chr4_-_94650134 0.17 ENSMUST00000053419.2
leucine rich repeat containing 19
chr17_+_12119274 0.16 ENSMUST00000024594.2
1-acylglycerol-3-phosphate O-acyltransferase 4 (lysophosphatidic acid acyltransferase, delta)
chr17_+_46202740 0.16 ENSMUST00000087031.5
exportin 5
chr19_-_5894100 0.16 ENSMUST00000055911.4
tigger transposable element derived 3
chr2_-_69712461 0.16 ENSMUST00000102706.3
ENSMUST00000073152.6
FAST kinase domains 1
chr2_-_6721890 0.15 ENSMUST00000114927.2
CUGBP, Elav-like family member 2
chr3_-_127837419 0.15 ENSMUST00000051737.6
adaptor-related protein complex 1 associated regulatory protein
chr11_-_87074055 0.14 ENSMUST00000020804.7
glycerophosphodiester phosphodiesterase domain containing 1
chrX_+_169879596 0.14 ENSMUST00000112105.1
ENSMUST00000078947.5
midline 1
chr14_+_101840602 0.14 ENSMUST00000159314.1
LIM domain only 7
chr14_+_65605267 0.14 ENSMUST00000079469.6
nuclear GTPase, germinal center associated
chr10_+_38965515 0.13 ENSMUST00000019992.5
laminin, alpha 4
chr9_+_51280295 0.13 ENSMUST00000050829.1
RIKEN cDNA 2010007H06 gene
chr14_+_49172202 0.13 ENSMUST00000153488.1
N(alpha)-acetyltransferase 30, NatC catalytic subunit
chr9_-_57645561 0.13 ENSMUST00000034863.6
c-src tyrosine kinase
chr10_+_28668560 0.13 ENSMUST00000161345.1
thymocyte selection associated
chr8_-_60954726 0.13 ENSMUST00000110302.1
chloride channel 3
chr2_-_91636394 0.13 ENSMUST00000111335.1
ENSMUST00000028681.8
coagulation factor II
chr2_+_144823666 0.13 ENSMUST00000028918.2
SCP2 sterol-binding domain containing 1
chr8_+_79028317 0.13 ENSMUST00000087927.4
ENSMUST00000098614.2
zinc finger protein 827
chr7_+_120677579 0.13 ENSMUST00000060175.6
cDNA sequence BC030336
chr17_-_80480435 0.13 ENSMUST00000068714.5
son of sevenless homolog 1 (Drosophila)
chr6_-_3498297 0.12 ENSMUST00000183736.1
HEPACAM family member 2
chr15_-_98871175 0.12 ENSMUST00000178486.2
ENSMUST00000023741.9
lysine (K)-specific methyltransferase 2D
chr6_-_52218686 0.12 ENSMUST00000134367.2
homeobox A7
chr15_-_50889691 0.12 ENSMUST00000165201.2
ENSMUST00000184458.1
trichorhinophalangeal syndrome I (human)
chr11_+_3649759 0.12 ENSMUST00000140242.1
microrchidia 2A
chr19_-_10604258 0.11 ENSMUST00000037678.6
dihydroxyacetone kinase 2 homolog (yeast)
chr11_-_54068932 0.11 ENSMUST00000093109.4
ENSMUST00000018755.3
PDZ and LIM domain 4
chr4_+_125029992 0.11 ENSMUST00000030684.7
guanine nucleotide binding protein-like 2 (nucleolar)
chr2_+_163658370 0.11 ENSMUST00000164399.1
ENSMUST00000064703.6
ENSMUST00000099105.2
ENSMUST00000152418.1
ENSMUST00000126182.1
ENSMUST00000131228.1
protein kinase inhibitor, gamma
chr12_+_31265234 0.10 ENSMUST00000169088.1
laminin B1
chr7_-_144939823 0.10 ENSMUST00000093962.4
cyclin D1
chrX_+_6415736 0.10 ENSMUST00000143641.3
shroom family member 4
chr5_-_131538687 0.10 ENSMUST00000161374.1
autism susceptibility candidate 2
chr10_-_13388753 0.10 ENSMUST00000105546.1
phosphatase and actin regulator 2
chr17_-_34603675 0.10 ENSMUST00000015622.7
ring finger protein 5
chr1_+_87183310 0.10 ENSMUST00000044533.8
protease, serine 56
chr3_+_53463666 0.10 ENSMUST00000058577.4
proline and serine rich 1
chr2_+_124610573 0.10 ENSMUST00000103239.3
ENSMUST00000103240.2
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
chr9_-_110117303 0.10 ENSMUST00000136969.1
DEAH (Asp-Glu-Ala-His) box polypeptide 30
chr4_-_43483696 0.09 ENSMUST00000030180.6
suppression inducing transmembrane adaptor 1
chr13_-_97747399 0.09 ENSMUST00000144993.1
RIKEN cDNA 5330416C01 gene
chr4_+_62583568 0.09 ENSMUST00000098031.3
regulator of G-protein signaling 3
chr7_+_87246649 0.09 ENSMUST00000068829.5
ENSMUST00000032781.7
NADPH oxidase 4
chr9_-_45984816 0.08 ENSMUST00000172450.1
platelet-activating factor acetylhydrolase, isoform 1b, subunit 2
chr13_-_54687644 0.08 ENSMUST00000129881.1
ring finger protein 44
chr7_+_27591513 0.08 ENSMUST00000108344.2
thymoma viral proto-oncogene 2
chr12_+_53248677 0.08 ENSMUST00000101432.2
neuronal PAS domain protein 3
chr1_+_161142706 0.08 ENSMUST00000111608.1
ENSMUST00000052245.8
ankyrin repeat domain 45
chr6_+_83137089 0.08 ENSMUST00000121093.1
ENSMUST00000087938.4
rhotekin
chr5_-_138155694 0.07 ENSMUST00000132318.1
ENSMUST00000049393.8
zinc finger protein 113
chr12_+_119945957 0.07 ENSMUST00000058644.8
transmembrane protein 196
chr7_-_27195727 0.07 ENSMUST00000163311.2
ENSMUST00000126211.1
small nuclear ribonucleoprotein polypeptide A
chr11_+_3330781 0.07 ENSMUST00000136536.1
ENSMUST00000093399.4
phosphoinositide-3-kinase interacting protein 1
chr2_+_157087042 0.07 ENSMUST00000166140.1
TBC/LysM associated domain containing 2
chr7_+_127233227 0.07 ENSMUST00000056232.6
zinc finger protein 553
chr8_-_69184177 0.07 ENSMUST00000185176.1
leucine zipper, putative tumor suppressor 1
chr11_-_101302206 0.06 ENSMUST00000140706.1
ENSMUST00000170502.1
ENSMUST00000172233.1
ENSMUST00000130916.1
beclin 1, autophagy related
chr2_-_165034821 0.06 ENSMUST00000153905.1
ENSMUST00000040381.8
nuclear receptor coactivator 5
chrX_+_99975570 0.06 ENSMUST00000113779.1
ENSMUST00000113776.1
ENSMUST00000113775.1
ENSMUST00000113780.1
ENSMUST00000113778.1
ENSMUST00000113781.1
ENSMUST00000113783.1
ENSMUST00000071453.2
ENSMUST00000113777.1
ectodysplasin-A
chr11_+_46055973 0.06 ENSMUST00000011400.7
a disintegrin and metallopeptidase domain 19 (meltrin beta)
chr3_-_144205165 0.06 ENSMUST00000120539.1
LIM domain only 4
chr17_+_28691419 0.06 ENSMUST00000124886.1
mitogen-activated protein kinase 14
chr9_-_35267746 0.06 ENSMUST00000125087.1
ENSMUST00000121564.1
ENSMUST00000063782.5
ENSMUST00000059057.7
family with sequence similarity 118, member B
chr13_+_109903089 0.06 ENSMUST00000120664.1
phosphodiesterase 4D, cAMP specific
chr5_-_147307264 0.06 ENSMUST00000031650.3
caudal type homeobox 2
chr17_-_35697971 0.05 ENSMUST00000146472.1
discoidin domain receptor family, member 1
chr12_-_16800674 0.05 ENSMUST00000162112.1
gene regulated by estrogen in breast cancer protein
chr17_+_3326552 0.05 ENSMUST00000169838.1
T cell lymphoma invasion and metastasis 2
chr18_+_82914632 0.05 ENSMUST00000071233.6
zinc finger protein 516
chr4_+_141746672 0.05 ENSMUST00000038161.4
agmatine ureohydrolase (agmatinase)
chr6_-_122340200 0.04 ENSMUST00000159384.1
polyhomeotic-like 1 (Drosophila)
chr4_+_132638987 0.04 ENSMUST00000135299.1
ENSMUST00000081726.6
ENSMUST00000180250.1
ENSMUST00000020197.7
ENSMUST00000079157.4
eyes absent 3 homolog (Drosophila)
chr7_+_127233044 0.04 ENSMUST00000106312.3
zinc finger protein 553
chr4_-_26346882 0.04 ENSMUST00000041374.7
ENSMUST00000153813.1
mannosidase, endo-alpha
chr4_-_141599835 0.04 ENSMUST00000141518.1
ENSMUST00000127455.1
ENSMUST00000105784.1
ENSMUST00000147785.1
filamin binding LIM protein 1
chr4_+_32983008 0.04 ENSMUST00000098190.3
ENSMUST00000029946.7
Ras-related GTP binding D

Network of associatons between targets according to the STRING database.

First level regulatory network of Tcf7l1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0033624 negative regulation of integrin activation(GO:0033624)
0.2 0.7 GO:0043397 corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397) positive regulation of corticotropin-releasing hormone secretion(GO:0051466) regulation of G-protein coupled receptor internalization(GO:1904020)
0.2 0.6 GO:0060983 epicardium-derived cardiac vascular smooth muscle cell differentiation(GO:0060983)
0.2 0.9 GO:0046684 response to pyrethroid(GO:0046684)
0.2 0.5 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.1 0.4 GO:0071707 immunoglobulin heavy chain V-D-J recombination(GO:0071707)
0.1 0.5 GO:1904616 regulation of actin filament binding(GO:1904529) regulation of actin binding(GO:1904616)
0.1 0.3 GO:0010513 phospholipase C-activating serotonin receptor signaling pathway(GO:0007208) positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.1 1.5 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.1 1.4 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977)
0.1 0.3 GO:0070602 regulation of chondrocyte development(GO:0061181) regulation of centromeric sister chromatid cohesion(GO:0070602)
0.1 0.5 GO:0045578 negative regulation of B cell differentiation(GO:0045578)
0.1 0.3 GO:2000686 regulation of rubidium ion transmembrane transporter activity(GO:2000686)
0.1 0.5 GO:0090666 scaRNA localization to Cajal body(GO:0090666)
0.1 0.4 GO:2000383 ectodermal cell fate commitment(GO:0001712) regulation of ectoderm development(GO:2000383) negative regulation of ectoderm development(GO:2000384)
0.1 0.4 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.1 0.2 GO:1900368 regulation of RNA interference(GO:1900368)
0.1 0.5 GO:0071787 regulation of L-glutamate transport(GO:0002036) endoplasmic reticulum tubular network assembly(GO:0071787)
0.1 0.9 GO:0051292 nuclear pore complex assembly(GO:0051292)
0.1 1.1 GO:0015809 arginine transport(GO:0015809)
0.1 0.2 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.1 0.4 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.1 0.4 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.1 0.2 GO:0001180 transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript(GO:0001180)
0.1 0.6 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290) negative regulation of type I interferon-mediated signaling pathway(GO:0060339)
0.1 0.3 GO:0010936 negative regulation of macrophage cytokine production(GO:0010936)
0.1 0.3 GO:0071494 cellular response to UV-C(GO:0071494)
0.1 0.8 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.1 0.5 GO:0038026 reelin-mediated signaling pathway(GO:0038026)
0.1 0.4 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
0.0 0.4 GO:0010815 bradykinin catabolic process(GO:0010815) ubiquitin homeostasis(GO:0010992)
0.0 0.2 GO:0006235 dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212) dTTP metabolic process(GO:0046075)
0.0 0.2 GO:0051684 maintenance of Golgi location(GO:0051684)
0.0 0.1 GO:0097401 synaptic vesicle lumen acidification(GO:0097401)
0.0 0.2 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.2 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
0.0 0.4 GO:1904816 positive regulation of protein localization to chromosome, telomeric region(GO:1904816)
0.0 0.1 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.0 0.4 GO:0089711 L-glutamate transmembrane transport(GO:0089711) L-alpha-amino acid transmembrane transport(GO:1902475)
0.0 0.1 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
0.0 0.4 GO:0043247 telomere maintenance in response to DNA damage(GO:0043247)
0.0 0.1 GO:1900738 positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
0.0 0.4 GO:0070932 histone H3 deacetylation(GO:0070932)
0.0 0.6 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
0.0 0.2 GO:0000189 MAPK import into nucleus(GO:0000189)
0.0 0.2 GO:0006776 vitamin A metabolic process(GO:0006776)
0.0 0.2 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.0 0.5 GO:0006337 nucleosome disassembly(GO:0006337)
0.0 0.2 GO:0032790 ribosome disassembly(GO:0032790)
0.0 0.1 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989)
0.0 0.2 GO:0010587 miRNA catabolic process(GO:0010587)
0.0 0.3 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.1 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.0 0.3 GO:0021707 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0 0.3 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.0 0.1 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.0 0.1 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.1 GO:0097473 cellular response to light intensity(GO:0071484) cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473)
0.0 0.1 GO:0007296 vitellogenesis(GO:0007296)
0.0 0.1 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
0.0 0.4 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.0 0.1 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 0.6 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.1 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
0.0 0.6 GO:0050892 intestinal absorption(GO:0050892)
0.0 0.1 GO:0000320 re-entry into mitotic cell cycle(GO:0000320)
0.0 0.6 GO:0070207 protein homotrimerization(GO:0070207)
0.0 0.1 GO:0030576 Cajal body organization(GO:0030576)
0.0 0.2 GO:0021819 layer formation in cerebral cortex(GO:0021819)
0.0 0.4 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.1 GO:0051987 positive regulation of attachment of spindle microtubules to kinetochore(GO:0051987)
0.0 0.3 GO:0045821 positive regulation of glycolytic process(GO:0045821)
0.0 0.1 GO:2001184 positive regulation of interleukin-12 secretion(GO:2001184)
0.0 0.0 GO:0009446 spermidine biosynthetic process(GO:0008295) putrescine biosynthetic process(GO:0009446)
0.0 0.2 GO:0060539 diaphragm development(GO:0060539)
0.0 0.1 GO:0002566 somatic diversification of immune receptors via somatic mutation(GO:0002566) somatic hypermutation of immunoglobulin genes(GO:0016446)
0.0 0.5 GO:1901998 toxin transport(GO:1901998)
0.0 0.3 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.1 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0008623 CHRAC(GO:0008623)
0.1 0.6 GO:0044094 host cell nucleus(GO:0042025) host cell nuclear part(GO:0044094)
0.1 0.4 GO:0097058 CRLF-CLCF1 complex(GO:0097058)
0.1 0.5 GO:0005784 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.1 0.5 GO:0044530 supraspliceosomal complex(GO:0044530)
0.1 0.6 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.1 0.2 GO:1990032 parallel fiber(GO:1990032)
0.1 0.7 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.1 0.2 GO:0042272 nucleocytoplasmic shuttling complex(GO:0031074) nuclear RNA export factor complex(GO:0042272)
0.0 0.9 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.1 GO:0005607 laminin-2 complex(GO:0005607)
0.0 0.9 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.1 GO:0031417 NatC complex(GO:0031417)
0.0 0.6 GO:0045179 apical cortex(GO:0045179)
0.0 0.2 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 1.3 GO:0051233 spindle midzone(GO:0051233)
0.0 0.2 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.0 0.5 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 0.4 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.0 0.2 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 0.2 GO:0042382 paraspeckles(GO:0042382)
0.0 0.5 GO:0071564 npBAF complex(GO:0071564)
0.0 1.4 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.1 GO:0034271 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.0 0.3 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.4 GO:0045120 pronucleus(GO:0045120)
0.0 0.1 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.2 GO:0031143 pseudopodium(GO:0031143)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.1 1.1 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.1 0.4 GO:0008311 double-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008311)
0.1 0.6 GO:0004111 creatine kinase activity(GO:0004111)
0.1 0.4 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.1 0.4 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.1 0.6 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.1 0.4 GO:0000099 sulfur amino acid transmembrane transporter activity(GO:0000099)
0.1 0.2 GO:0033680 ATP-dependent DNA/RNA helicase activity(GO:0033680)
0.1 0.2 GO:0038025 reelin receptor activity(GO:0038025)
0.1 0.3 GO:0004382 guanosine-diphosphatase activity(GO:0004382)
0.1 0.4 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.1 0.4 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.1 0.4 GO:0043559 insulin binding(GO:0043559)
0.1 0.2 GO:0035650 AP-1 adaptor complex binding(GO:0035650)
0.0 0.3 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.0 0.4 GO:0005127 ciliary neurotrophic factor receptor binding(GO:0005127)
0.0 0.2 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.0 0.4 GO:0034711 inhibin binding(GO:0034711)
0.0 0.9 GO:0031402 sodium ion binding(GO:0031402)
0.0 1.3 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.9 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.1 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.0 0.6 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.3 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993) serotonin binding(GO:0051378)
0.0 0.8 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.1 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.0 0.3 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.0 0.2 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.0 0.2 GO:0070883 pre-miRNA binding(GO:0070883)
0.0 0.5 GO:0031005 filamin binding(GO:0031005)
0.0 0.1 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.0 0.2 GO:0015197 peptide transporter activity(GO:0015197)
0.0 1.4 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.2 GO:0016918 retinal binding(GO:0016918) retinol binding(GO:0019841)
0.0 0.2 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.0 0.1 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.0 0.3 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.1 GO:0043208 glycosphingolipid binding(GO:0043208)
0.0 0.4 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.5 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 0.9 GO:0042805 actinin binding(GO:0042805)
0.0 0.3 GO:0070410 co-SMAD binding(GO:0070410)
0.0 0.4 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.1 GO:0016175 NAD(P)H oxidase activity(GO:0016174) superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.2 GO:0001163 RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.0 0.3 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.2 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.4 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.3 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.1 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.2 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 0.5 GO:0031492 nucleosomal DNA binding(GO:0031492)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.5 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.4 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.5 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.1 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.6 PID RHOA PATHWAY RhoA signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 1.0 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 0.4 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 1.5 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.3 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.6 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.5 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.1 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.6 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.5 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.2 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.0 0.3 REACTOME SOS MEDIATED SIGNALLING Genes involved in SOS-mediated signalling
0.0 0.4 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.1 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.3 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 0.3 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.4 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis