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2D miR_HR1_12

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Results for Spic

Z-value: 1.39

Motif logo

Transcription factors associated with Spic

Gene Symbol Gene ID Gene Info
ENSMUSG00000004359.10 Spi-C transcription factor (Spi-1/PU.1 related)

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Spicmm10_v2_chr10_-_88683021_886830250.156.4e-01Click!

Activity profile of Spic motif

Sorted Z-values of Spic motif

Promoter Log-likelihood Transcript Gene Gene Info
chr3_-_106167564 1.76 ENSMUST00000063062.8
chitinase 3-like 3
chr19_-_40994133 1.44 ENSMUST00000117695.1
B cell linker
chr7_-_45238794 1.33 ENSMUST00000098461.1
ENSMUST00000107797.1
CD37 antigen
chr15_+_78244781 1.29 ENSMUST00000096357.5
ENSMUST00000133618.1
neutrophil cytosolic factor 4
chr12_+_112760652 1.21 ENSMUST00000063888.3
phospholipase D family, member 4
chr7_-_126704179 1.20 ENSMUST00000106364.1
coronin, actin binding protein 1A
chr15_-_103340085 1.19 ENSMUST00000168828.1
zinc finger protein 385A
chr14_+_103046977 1.18 ENSMUST00000022722.6
immunoresponsive gene 1
chr17_-_35172608 1.17 ENSMUST00000173106.1
allograft inflammatory factor 1
chr7_-_122132844 1.16 ENSMUST00000106469.1
ENSMUST00000063587.6
ENSMUST00000106468.1
ENSMUST00000130149.1
ENSMUST00000098068.3
partner and localizer of BRCA2
chr7_-_126704736 1.13 ENSMUST00000131415.1
coronin, actin binding protein 1A
chr19_-_11604828 1.11 ENSMUST00000025582.4
membrane-spanning 4-domains, subfamily A, member 6D
chr19_+_6084983 1.08 ENSMUST00000025704.2
cell division cycle associated 5
chr7_-_45239108 1.05 ENSMUST00000033063.6
CD37 antigen
chr4_-_136892867 1.00 ENSMUST00000046332.5
complement component 1, q subcomponent, C chain
chr8_-_122432924 0.98 ENSMUST00000017604.8
cytochrome b-245, alpha polypeptide
chr7_-_45239041 0.98 ENSMUST00000131290.1
CD37 antigen
chr11_-_79523760 0.98 ENSMUST00000179322.1
ecotropic viral integration site 2b
chrX_+_107089234 0.97 ENSMUST00000118666.1
ENSMUST00000053375.3
purinergic receptor P2Y, G-protein coupled 10
chr7_-_126704522 0.96 ENSMUST00000135087.1
coronin, actin binding protein 1A
chr9_+_56089962 0.96 ENSMUST00000059206.7
proline-serine-threonine phosphatase-interacting protein 1
chr3_+_87435820 0.92 ENSMUST00000178261.1
ENSMUST00000049926.8
ENSMUST00000166297.1
Fc receptor-like 5
chrX_-_101734125 0.90 ENSMUST00000056614.6
chemokine (C-X-C motif) receptor 3
chr2_+_152847961 0.89 ENSMUST00000164120.1
ENSMUST00000178997.1
ENSMUST00000109816.1
TPX2, microtubule-associated protein homolog (Xenopus laevis)
chr16_-_75909272 0.88 ENSMUST00000114239.2
SAM domain, SH3 domain and nuclear localization signals, 1
chr4_+_138775735 0.86 ENSMUST00000030528.2
phospholipase A2, group IID
chr17_+_57279094 0.86 ENSMUST00000169220.2
ENSMUST00000005889.9
ENSMUST00000112870.4
vav 1 oncogene
chr7_+_28982832 0.86 ENSMUST00000085835.6
mitogen-activated protein kinase kinase kinase kinase 1
chr3_-_106790143 0.85 ENSMUST00000038845.8
CD53 antigen
chr13_-_49309217 0.85 ENSMUST00000110087.2
FYVE, RhoGEF and PH domain containing 3
chr2_+_152847993 0.84 ENSMUST00000028969.8
TPX2, microtubule-associated protein homolog (Xenopus laevis)
chr7_+_126695942 0.83 ENSMUST00000106369.1
bolA-like 2 (E. coli)
chr16_-_36642742 0.82 ENSMUST00000135280.1
CD86 antigen
chr4_+_130913264 0.82 ENSMUST00000156225.1
ENSMUST00000156742.1
lysosomal-associated protein transmembrane 5
chr12_-_3426700 0.81 ENSMUST00000180149.1
RIKEN cDNA 1110002L01 gene
chr7_+_43408187 0.80 ENSMUST00000005592.6
sialic acid binding Ig-like lectin G
chr12_+_98268626 0.80 ENSMUST00000075072.4
G-protein coupled receptor 65
chr6_+_123229843 0.78 ENSMUST00000112554.2
ENSMUST00000024118.4
ENSMUST00000117130.1
C-type lectin domain family 4, member n
chr11_-_83020788 0.78 ENSMUST00000038141.8
ENSMUST00000092838.4
schlafen 8
chr1_-_170976112 0.77 ENSMUST00000027966.7
ENSMUST00000081103.5
ENSMUST00000159688.1
Fc receptor, IgG, low affinity IIb
chr3_-_105932664 0.74 ENSMUST00000098758.2
RIKEN cDNA I830077J02 gene
chr7_+_128062657 0.74 ENSMUST00000120355.1
ENSMUST00000106240.2
ENSMUST00000098015.3
integrin alpha M
chr4_+_130913120 0.74 ENSMUST00000151698.1
lysosomal-associated protein transmembrane 5
chr13_-_97137877 0.72 ENSMUST00000073456.7
NSA2 ribosome biogenesis homolog (S. cerevisiae)
chr15_+_103453782 0.72 ENSMUST00000047405.7
NCK associated protein 1 like
chr7_+_142460834 0.72 ENSMUST00000018963.4
ENSMUST00000105967.1
lymphocyte specific 1
chrX_+_107255878 0.72 ENSMUST00000101294.2
ENSMUST00000118820.1
ENSMUST00000120971.1
G protein-coupled receptor 174
chr1_+_87620334 0.72 ENSMUST00000042275.8
ENSMUST00000168783.1
inositol polyphosphate-5-phosphatase D
chr17_-_33955658 0.71 ENSMUST00000174609.2
ENSMUST00000008812.7
ribosomal protein S18
chr1_-_144249134 0.71 ENSMUST00000172388.1
regulator of G-protein signaling 1
chr1_+_171895664 0.70 ENSMUST00000097466.2
predicted gene 10521
chr9_+_89199209 0.69 ENSMUST00000068569.4
B cell leukemia/lymphoma 2 related protein A1b
chr1_+_74375203 0.69 ENSMUST00000027368.5
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 1
chr8_-_39642669 0.68 ENSMUST00000026021.6
ENSMUST00000170091.1
macrophage scavenger receptor 1
chr4_+_44300876 0.68 ENSMUST00000045607.5
maternal embryonic leucine zipper kinase
chr9_+_106222598 0.68 ENSMUST00000062241.9
toll-like receptor 9
chr13_+_30749226 0.67 ENSMUST00000021784.2
ENSMUST00000110307.1
interferon regulatory factor 4
chr1_-_171234290 0.65 ENSMUST00000079957.6
Fc receptor, IgE, high affinity I, gamma polypeptide
chr10_-_63244135 0.65 ENSMUST00000054837.3
RIKEN cDNA 1700120B22 gene
chr2_+_24345282 0.65 ENSMUST00000114485.2
interleukin 1 receptor antagonist
chr10_-_117282262 0.65 ENSMUST00000092163.7
lysozyme 2
chr11_-_115133981 0.64 ENSMUST00000106561.1
ENSMUST00000051264.7
ENSMUST00000106562.2
CD300 antigen like family member F
chr6_-_136941694 0.64 ENSMUST00000032344.5
Rho, GDP dissociation inhibitor (GDI) beta
chrX_-_134541847 0.63 ENSMUST00000054213.4
translocase of inner mitochondrial membrane 8A1
chr2_+_129100995 0.62 ENSMUST00000103205.4
ENSMUST00000028874.7
polymerase (RNA) I polypeptide B
chr1_-_149961230 0.61 ENSMUST00000070200.8
phospholipase A2, group IVA (cytosolic, calcium-dependent)
chr5_+_86071734 0.61 ENSMUST00000031171.7
signal transducing adaptor family member 1
chr8_-_70897407 0.59 ENSMUST00000054220.8
ribosomal protein L18A
chr10_-_39986625 0.59 ENSMUST00000170579.1
ENSMUST00000045524.6
ENSMUST00000073618.5
ENSMUST00000164566.1
cDNA sequence BC021785
chr4_-_136886187 0.59 ENSMUST00000046384.8
complement component 1, q subcomponent, beta polypeptide
chr7_-_127042420 0.59 ENSMUST00000032915.6
kinesin family member 22
chr10_-_89443888 0.59 ENSMUST00000099374.2
ENSMUST00000105298.1
growth arrest-specific 2 like 3
chr2_+_24345305 0.58 ENSMUST00000114482.1
interleukin 1 receptor antagonist
chr1_-_20820213 0.58 ENSMUST00000053266.9
minichromosome maintenance deficient 3 (S. cerevisiae)
chr7_+_142460809 0.58 ENSMUST00000105968.1
lymphocyte specific 1
chr7_+_126584937 0.58 ENSMUST00000039522.6
apolipoprotein B receptor
chr3_-_96293953 0.58 ENSMUST00000029748.3
Fc receptor, IgG, high affinity I
chr17_+_55749978 0.57 ENSMUST00000025004.6
EGF-like module containing, mucin-like, hormone receptor-like sequence 4
chr11_-_97782377 0.57 ENSMUST00000128801.1
ribosomal protein L23
chr1_+_87620306 0.56 ENSMUST00000169754.1
inositol polyphosphate-5-phosphatase D
chr1_-_179546261 0.56 ENSMUST00000027769.5
transcription factor B2, mitochondrial
chr2_+_43748802 0.55 ENSMUST00000112824.1
ENSMUST00000055776.7
Rho GTPase activating protein 15
chr11_-_83020722 0.55 ENSMUST00000108152.2
schlafen 8
chr3_+_95526777 0.54 ENSMUST00000015667.2
ENSMUST00000116304.2
cathepsin S
chr5_-_138170992 0.54 ENSMUST00000139983.1
minichromosome maintenance deficient 7 (S. cerevisiae)
chr8_+_66386292 0.53 ENSMUST00000039540.5
ENSMUST00000110253.2
membrane-associated ring finger (C3HC4) 1
chr11_-_115062177 0.53 ENSMUST00000062787.7
CD300e antigen
chr1_+_152807877 0.53 ENSMUST00000027754.6
neutrophil cytosolic factor 2
chr7_+_126695355 0.53 ENSMUST00000130498.1
bolA-like 2 (E. coli)
chr5_-_138171248 0.52 ENSMUST00000153867.1
minichromosome maintenance deficient 7 (S. cerevisiae)
chr11_+_98907801 0.52 ENSMUST00000092706.6
cell division cycle 6
chr6_+_29529277 0.52 ENSMUST00000163511.1
interferon regulatory factor 5
chr6_-_136941887 0.52 ENSMUST00000111891.1
Rho, GDP dissociation inhibitor (GDI) beta
chr10_-_117063764 0.52 ENSMUST00000047672.7
chaperonin containing Tcp1, subunit 2 (beta)
chr3_+_87376381 0.52 ENSMUST00000163661.1
ENSMUST00000072480.2
ENSMUST00000167200.1
Fc receptor-like 1
chr1_+_72711259 0.51 ENSMUST00000059980.9
ribosomal protein L37a
chr4_+_45018583 0.51 ENSMUST00000133157.1
ENSMUST00000029999.8
ENSMUST00000107814.3
polymerase (RNA) I polypeptide E
chr8_+_107056870 0.50 ENSMUST00000034392.5
ENSMUST00000170962.1
nuclear import 7 homolog (S. cerevisiae)
chr12_-_11265768 0.50 ENSMUST00000166117.1
Gen homolog 1, endonuclease (Drosophila)
chr1_+_171840607 0.50 ENSMUST00000136479.1
ENSMUST00000042302.6
CD84 antigen
chr5_-_92435114 0.50 ENSMUST00000135112.1
nucleoporin 54
chr10_-_128626464 0.50 ENSMUST00000026420.5
ribosomal protein S26
chr1_+_87574016 0.49 ENSMUST00000166259.1
ENSMUST00000172222.1
ENSMUST00000163606.1
neuraminidase 2
chr19_+_4154606 0.49 ENSMUST00000061086.8
protein tyrosine phosphatase, receptor type, C polypeptide-associated protein
chr14_+_57524734 0.49 ENSMUST00000089494.4
interleukin 17D
chr2_+_22774081 0.49 ENSMUST00000014290.8
amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
chr7_+_28440927 0.49 ENSMUST00000078845.6
glia maturation factor, gamma
chr11_+_120458093 0.48 ENSMUST00000058370.7
ENSMUST00000175970.1
ENSMUST00000176120.1
coiled-coil domain containing 137
chr10_+_80292453 0.48 ENSMUST00000068408.7
ENSMUST00000062674.6
ribosomal protein S15
chr15_+_78430086 0.48 ENSMUST00000162808.1
potassium channel tetramerisation domain containing 17
chr11_-_97782409 0.48 ENSMUST00000103146.4
ribosomal protein L23
chr15_-_78305603 0.46 ENSMUST00000096356.3
colony stimulating factor 2 receptor, beta 2, low-affinity (granulocyte-macrophage)
chr6_-_136941494 0.46 ENSMUST00000111892.1
Rho, GDP dissociation inhibitor (GDI) beta
chr7_+_105640522 0.45 ENSMUST00000106785.1
ENSMUST00000106786.1
ENSMUST00000106780.1
ENSMUST00000106784.1
translocase of inner mitochondrial membrane 10B
chr7_+_30458280 0.45 ENSMUST00000126297.1
nephrosis 1, nephrin
chr1_-_171059390 0.45 ENSMUST00000164044.1
ENSMUST00000169017.1
Fc receptor, IgG, low affinity III
chr5_-_134229581 0.44 ENSMUST00000111275.1
ENSMUST00000016094.6
ENSMUST00000144086.1
neutrophil cytosolic factor 1
chr17_+_7925990 0.44 ENSMUST00000036370.7
T cell activation Rho GTPase activating protein
chr7_+_105640448 0.44 ENSMUST00000058333.3
translocase of inner mitochondrial membrane 10B
chr2_-_129371131 0.44 ENSMUST00000028881.7
interleukin 1 beta
chr8_+_125730005 0.44 ENSMUST00000143504.1
nucleoside-triphosphatase, cancer-related
chr19_+_3282901 0.43 ENSMUST00000025745.3
ENSMUST00000025743.6
mitochondrial ribosomal protein L21
chr8_-_85080652 0.43 ENSMUST00000152785.1
WD repeat domain containing 83
chr6_-_56704673 0.43 ENSMUST00000170382.2
LSM5 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr12_+_78861693 0.43 ENSMUST00000071230.7
eukaryotic translation initiation factor 2, subunit 1 alpha
chr8_+_94923687 0.43 ENSMUST00000153448.1
ENSMUST00000074570.3
ENSMUST00000166802.1
G protein-coupled receptor 114
chr11_-_70812539 0.42 ENSMUST00000074572.6
ENSMUST00000108534.2
SLP adaptor and CSK interacting membrane protein
chr15_-_66812593 0.42 ENSMUST00000100572.3
src-like adaptor
chr1_-_170927567 0.41 ENSMUST00000046322.7
ENSMUST00000159171.1
Fc receptor-like A
chr12_-_24493656 0.41 ENSMUST00000073088.2
predicted pseudogene 16372
chr5_-_138171216 0.41 ENSMUST00000147920.1
minichromosome maintenance deficient 7 (S. cerevisiae)
chr15_-_94543472 0.40 ENSMUST00000134061.1
ENSMUST00000049151.3
pseudouridylate synthase 7 homolog (S. cerevisiae)-like
chr4_-_49845549 0.39 ENSMUST00000093859.4
ENSMUST00000076674.3
glutamate receptor ionotropic, NMDA3A
chr19_+_12460749 0.39 ENSMUST00000081035.7
macrophage expressed gene 1
chr16_+_36934976 0.38 ENSMUST00000023531.8
hematopoietic cell specific Lyn substrate 1
chr11_+_70130329 0.38 ENSMUST00000041550.5
ENSMUST00000165951.1
macrophage galactose N-acetyl-galactosamine specific lectin 2
chr2_+_119112793 0.38 ENSMUST00000140939.1
ENSMUST00000028795.3
RAD51 homolog
chr4_-_86857365 0.37 ENSMUST00000102814.4
ribosomal protein S6
chr1_-_170927540 0.37 ENSMUST00000162136.1
ENSMUST00000162887.1
Fc receptor-like A
chr8_+_92855319 0.37 ENSMUST00000046290.1
lysophosphatidylcholine acyltransferase 2
chr3_+_95499273 0.36 ENSMUST00000015664.3
cathepsin K
chr15_+_76368884 0.36 ENSMUST00000023213.6
family with sequence similarity 203, member A
chr15_-_31601786 0.35 ENSMUST00000022842.8
chaperonin containing Tcp1, subunit 5 (epsilon)
chr6_+_137410721 0.35 ENSMUST00000167002.1
protein tyrosine phosphatase, receptor type, O
chr2_+_153031852 0.34 ENSMUST00000037235.6
X Kell blood group precursor related family member 7 homolog
chr11_-_17008647 0.34 ENSMUST00000102881.3
pleckstrin
chr9_-_60522017 0.33 ENSMUST00000140824.1
thrombospondin, type I, domain containing 4
chr1_-_144775419 0.33 ENSMUST00000027603.3
regulator of G-protein signaling 18
chr15_+_25843264 0.32 ENSMUST00000022881.7
family with sequence similarity 134, member B
chr19_+_11770415 0.32 ENSMUST00000167199.1
mitochondrial ribosomal protein L16
chr10_+_79879614 0.32 ENSMUST00000006679.8
proteinase 3
chr13_-_98262946 0.32 ENSMUST00000040972.2
UTP15, U3 small nucleolar ribonucleoprotein, homolog (yeast)
chr9_+_22225702 0.32 ENSMUST00000072465.7
zinc finger protein 809
chr12_+_84362029 0.32 ENSMUST00000110278.1
ENSMUST00000145522.1
coenzyme Q6 homolog (yeast)
chr1_+_40084764 0.31 ENSMUST00000027243.7
interleukin 1 receptor, type II
chr17_+_29360923 0.30 ENSMUST00000024810.6
FYVE, RhoGEF and PH domain containing 2
chr10_+_130322845 0.29 ENSMUST00000042586.8
thymocyte expressed, positive selection associated 1
chr15_-_80264276 0.29 ENSMUST00000052499.7
ribosomal protein S19 binding protein 1
chr14_+_55765956 0.28 ENSMUST00000057569.3
leukotriene B4 receptor 1
chr15_-_36608959 0.28 ENSMUST00000001809.8
poly(A) binding protein, cytoplasmic 1
chr17_+_34048280 0.28 ENSMUST00000143354.1
collagen, type XI, alpha 2
chr2_-_165400398 0.28 ENSMUST00000029213.4
osteoclast stimulatory transmembrane protein
chr8_+_123102344 0.28 ENSMUST00000000756.5
ribosomal protein L13
chr11_-_102880981 0.28 ENSMUST00000107060.1
elongation factor Tu GTP binding domain containing 2
chr3_+_95658771 0.27 ENSMUST00000178686.1
myeloid cell leukemia sequence 1
chr7_-_25658726 0.27 ENSMUST00000071329.6
branched chain ketoacid dehydrogenase E1, alpha polypeptide
chr1_+_36307745 0.27 ENSMUST00000142319.1
ENSMUST00000097778.2
ENSMUST00000115031.1
ENSMUST00000115032.1
ENSMUST00000137906.1
ENSMUST00000115029.1
AT rich interactive domain 5A (MRF1-like)
chr4_+_45848664 0.27 ENSMUST00000107783.1
RIKEN cDNA 1300002K09 gene
chr5_-_3893907 0.27 ENSMUST00000117463.1
ENSMUST00000044746.4
mitochondrial transcription termination factor
chr5_+_4192367 0.27 ENSMUST00000177258.1
predicted gene 9897
chr15_-_77596110 0.26 ENSMUST00000089465.4
apolipoprotein L 10B
chr2_+_180257373 0.26 ENSMUST00000059080.6
ribosomal protein S21
chr8_+_109493982 0.26 ENSMUST00000034162.6
polyamine modulated factor 1 binding protein 1
chr8_+_114439655 0.26 ENSMUST00000004756.7
ENSMUST00000109108.2
ENSMUST00000160862.1
ENSMUST00000109107.2
WW domain-containing oxidoreductase
chr2_-_25319095 0.26 ENSMUST00000114318.3
ENSMUST00000114310.3
ENSMUST00000114308.3
ENSMUST00000114317.3
ENSMUST00000028335.6
ENSMUST00000114314.3
ENSMUST00000114307.1
glutamate receptor, ionotropic, NMDA1 (zeta 1)
chr13_-_58128542 0.25 ENSMUST00000007980.6
heterogeneous nuclear ribonucleoprotein A0
chr9_+_108508005 0.25 ENSMUST00000006838.8
ENSMUST00000134939.1
glutaminyl-tRNA synthetase
chr9_+_124021965 0.24 ENSMUST00000039171.7
chemokine (C-C motif) receptor 3
chr1_+_118321834 0.24 ENSMUST00000027626.6
ENSMUST00000112688.3
Mki67 (FHA domain) interacting nucleolar phosphoprotein
chr17_+_48316141 0.24 ENSMUST00000049614.6
RIKEN cDNA B430306N03 gene
chr8_-_73353477 0.24 ENSMUST00000119826.1
like-glycosyltransferase
chr5_+_124439891 0.24 ENSMUST00000059580.4
SET domain containing (lysine methyltransferase) 8
chr2_-_77946180 0.23 ENSMUST00000111824.1
ENSMUST00000111819.1
ENSMUST00000128963.1
CWC22 spliceosome-associated protein homolog (S. cerevisiae)
chr6_-_8259098 0.23 ENSMUST00000012627.4
replication protein A3
chr19_+_6306456 0.23 ENSMUST00000025681.7
CDC42 binding protein kinase gamma (DMPK-like)
chr5_-_87092546 0.23 ENSMUST00000132667.1
ENSMUST00000145617.1
ENSMUST00000094649.4
UDP glucuronosyltransferase 2 family, polypeptide B36
chr1_-_33669745 0.23 ENSMUST00000027312.9
DNA primase, p58 subunit
chr6_+_48684544 0.23 ENSMUST00000118802.1
GTPase, IMAP family member 4
chr1_+_161494649 0.23 ENSMUST00000086084.1
tumor necrosis factor (ligand) superfamily, member 18
chr7_-_104369782 0.22 ENSMUST00000164410.1
tripartite motif-containing 30B
chr7_-_45124355 0.22 ENSMUST00000003521.8
ribosomal protein S11
chr4_-_133874682 0.22 ENSMUST00000168974.2
ribosomal protein S6 kinase polypeptide 1
chr5_-_35729276 0.22 ENSMUST00000070203.7
SH3 domain and tetratricopeptide repeats 1
chr11_+_120948480 0.22 ENSMUST00000070653.6
solute carrier family 16 (monocarboxylic acid transporters), member 3
chr1_-_164307443 0.22 ENSMUST00000027866.4
ENSMUST00000120447.1
ENSMUST00000086032.3
basic leucine zipper nuclear factor 1
chr9_-_63602464 0.22 ENSMUST00000080527.5
ENSMUST00000042322.4
IQ motif containing H
chr5_-_130003000 0.22 ENSMUST00000026613.7
glucuronidase, beta
chr12_+_55398775 0.22 ENSMUST00000021412.8
proteasome (prosome, macropain) subunit, alpha type 6
chr5_+_149265035 0.21 ENSMUST00000130144.1
ENSMUST00000071130.3
arachidonate 5-lipoxygenase activating protein
chr6_+_83326071 0.21 ENSMUST00000038658.8
ENSMUST00000101245.2
MOB kinase activator 1A

Network of associatons between targets according to the STRING database.

First level regulatory network of Spic

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.3 GO:0032796 uropod organization(GO:0032796)
0.4 1.7 GO:0001803 type III hypersensitivity(GO:0001802) regulation of type III hypersensitivity(GO:0001803) positive regulation of type III hypersensitivity(GO:0001805)
0.4 1.2 GO:1902162 regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:1902162)
0.4 3.4 GO:0030886 negative regulation of myeloid dendritic cell activation(GO:0030886)
0.4 1.1 GO:0034085 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.4 1.1 GO:0072717 cellular response to actinomycin D(GO:0072717)
0.3 1.0 GO:0002019 regulation of renal output by angiotensin(GO:0002019)
0.3 1.3 GO:0045659 negative regulation of neutrophil differentiation(GO:0045659)
0.3 1.5 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.3 1.2 GO:0014738 regulation of muscle hyperplasia(GO:0014738) muscle hyperplasia(GO:0014900)
0.3 0.8 GO:0002644 negative regulation of tolerance induction(GO:0002644)
0.3 1.3 GO:0002309 T cell proliferation involved in immune response(GO:0002309)
0.3 0.8 GO:0002884 regulation of type I hypersensitivity(GO:0001810) negative regulation of hypersensitivity(GO:0002884) type I hypersensitivity(GO:0016068)
0.2 1.0 GO:0006742 NADP catabolic process(GO:0006742)
0.2 0.7 GO:0036228 protein targeting to nuclear inner membrane(GO:0036228)
0.2 0.7 GO:0032741 positive regulation of interleukin-18 production(GO:0032741) positive regulation of toll-like receptor 9 signaling pathway(GO:0034165)
0.2 0.7 GO:0045404 interleukin-10 biosynthetic process(GO:0042091) interleukin-13 biosynthetic process(GO:0042231) regulation of interleukin-10 biosynthetic process(GO:0045074) positive regulation of interleukin-4 biosynthetic process(GO:0045404)
0.2 0.6 GO:0035666 TRIF-dependent toll-like receptor signaling pathway(GO:0035666)
0.2 1.6 GO:1901164 negative regulation of trophoblast cell migration(GO:1901164)
0.2 0.6 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760) regulation of macrophage colony-stimulating factor signaling pathway(GO:1902226) regulation of response to macrophage colony-stimulating factor(GO:1903969) regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903972)
0.2 0.6 GO:0032685 negative regulation of granulocyte macrophage colony-stimulating factor production(GO:0032685)
0.2 0.7 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.2 1.8 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.2 0.5 GO:0001180 transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript(GO:0001180)
0.2 0.5 GO:0071846 actin filament debranching(GO:0071846)
0.1 1.0 GO:0045650 negative regulation of macrophage differentiation(GO:0045650)
0.1 0.5 GO:0034769 basement membrane disassembly(GO:0034769)
0.1 0.7 GO:0014005 microglia differentiation(GO:0014004) microglia development(GO:0014005)
0.1 0.9 GO:0002361 CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361)
0.1 0.3 GO:0045869 negative regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045869)
0.1 0.5 GO:0090666 scaRNA localization to Cajal body(GO:0090666)
0.1 0.6 GO:0031394 positive regulation of prostaglandin biosynthetic process(GO:0031394) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.1 0.4 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.1 0.4 GO:0033092 positive regulation of immature T cell proliferation in thymus(GO:0033092) negative regulation of adiponectin secretion(GO:0070164)
0.1 0.3 GO:2000556 regulation of T-helper 1 cell cytokine production(GO:2000554) positive regulation of T-helper 1 cell cytokine production(GO:2000556)
0.1 0.3 GO:1900673 olefin metabolic process(GO:1900673)
0.1 0.5 GO:0002291 T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:0002291)
0.1 0.2 GO:0042494 detection of bacterial lipoprotein(GO:0042494)
0.1 0.2 GO:1904569 regulation of selenocysteine incorporation(GO:1904569)
0.1 0.6 GO:0007000 nucleolus organization(GO:0007000)
0.1 0.9 GO:0051280 negative regulation of release of sequestered calcium ion into cytosol(GO:0051280)
0.1 0.4 GO:0036151 phosphatidylcholine acyl-chain remodeling(GO:0036151)
0.1 0.6 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.1 0.4 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.1 0.3 GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.1 0.5 GO:0006689 ganglioside catabolic process(GO:0006689) oligosaccharide catabolic process(GO:0009313)
0.1 0.2 GO:1901355 response to rapamycin(GO:1901355)
0.1 0.6 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.1 0.9 GO:1900118 negative regulation of execution phase of apoptosis(GO:1900118)
0.1 0.3 GO:0070560 negative regulation of inositol phosphate biosynthetic process(GO:0010920) protein secretion by platelet(GO:0070560)
0.1 0.3 GO:0097029 mature conventional dendritic cell differentiation(GO:0097029)
0.1 0.3 GO:0090070 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.1 0.2 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.1 0.7 GO:0010886 positive regulation of cholesterol storage(GO:0010886)
0.1 1.3 GO:0045730 respiratory burst(GO:0045730)
0.1 0.6 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.1 0.2 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.1 0.3 GO:0003105 negative regulation of glomerular filtration(GO:0003105)
0.1 1.8 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.1 0.1 GO:0002513 tolerance induction to self antigen(GO:0002513) endocardial cushion fusion(GO:0003274) positive regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000563)
0.1 0.3 GO:0060023 soft palate development(GO:0060023)
0.1 0.3 GO:0090290 positive regulation of osteoclast proliferation(GO:0090290)
0.1 0.2 GO:0002538 arachidonic acid metabolite production involved in inflammatory response(GO:0002538) leukotriene production involved in inflammatory response(GO:0002540)
0.1 1.0 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.1 0.9 GO:1901741 positive regulation of myoblast fusion(GO:1901741)
0.0 0.4 GO:0090267 positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267)
0.0 0.0 GO:0006404 RNA import into nucleus(GO:0006404)
0.0 0.4 GO:1904869 protein localization to nuclear body(GO:1903405) positive regulation of establishment of protein localization to telomere(GO:1904851) protein localization to Cajal body(GO:1904867) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871) protein localization to nucleoplasm(GO:1990173)
0.0 0.2 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.0 0.2 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 1.1 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.3 GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447)
0.0 0.1 GO:0071211 protein targeting to vacuole involved in autophagy(GO:0071211) lysosomal membrane organization(GO:0097212) positive regulation of protein folding(GO:1903334)
0.0 0.1 GO:0051987 positive regulation of attachment of spindle microtubules to kinetochore(GO:0051987)
0.0 0.2 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
0.0 1.0 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.0 0.6 GO:0006744 ubiquinone biosynthetic process(GO:0006744)
0.0 1.2 GO:0060236 regulation of mitotic spindle organization(GO:0060236)
0.0 0.1 GO:1900157 regulation of bone mineralization involved in bone maturation(GO:1900157)
0.0 0.6 GO:0000338 protein deneddylation(GO:0000338)
0.0 0.1 GO:0045085 negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.0 0.4 GO:0045649 positive regulation of granulocyte differentiation(GO:0030854) regulation of macrophage differentiation(GO:0045649) positive regulation of macrophage differentiation(GO:0045651)
0.0 0.9 GO:0045954 positive regulation of natural killer cell mediated cytotoxicity(GO:0045954)
0.0 0.3 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.3 GO:2000400 positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.0 0.4 GO:0001522 pseudouridine synthesis(GO:0001522)
0.0 0.1 GO:0018317 protein C-linked glycosylation(GO:0018103) peptidyl-tryptophan modification(GO:0018211) protein C-linked glycosylation via tryptophan(GO:0018317) protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan(GO:0018406)
0.0 0.2 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.0 0.7 GO:0050832 defense response to fungus(GO:0050832)
0.0 0.1 GO:2000686 regulation of rubidium ion transmembrane transporter activity(GO:2000686)
0.0 0.1 GO:0035633 cyclooxygenase pathway(GO:0019371) maintenance of blood-brain barrier(GO:0035633)
0.0 0.4 GO:0060134 prepulse inhibition(GO:0060134)
0.0 0.2 GO:0032790 ribosome disassembly(GO:0032790)
0.0 0.2 GO:0051596 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.0 0.6 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.0 0.1 GO:0051025 negative regulation of immunoglobulin secretion(GO:0051025)
0.0 0.5 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495)
0.0 0.0 GO:1901950 dense core granule localization(GO:0032253) dense core granule transport(GO:1901950) regulation of dense core granule transport(GO:1904809) positive regulation of dense core granule transport(GO:1904811)
0.0 0.2 GO:0097531 mast cell chemotaxis(GO:0002551) eosinophil chemotaxis(GO:0048245) mast cell migration(GO:0097531)
0.0 0.1 GO:0071051 polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.0 0.2 GO:0015727 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
0.0 0.2 GO:0051103 DNA ligation involved in DNA repair(GO:0051103)
0.0 0.1 GO:0070315 G1 to G0 transition involved in cell differentiation(GO:0070315)
0.0 0.2 GO:0031547 brain-derived neurotrophic factor receptor signaling pathway(GO:0031547)
0.0 0.3 GO:2001241 positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241)
0.0 0.1 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.0 0.1 GO:0060454 positive regulation of gastric acid secretion(GO:0060454) membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
0.0 0.7 GO:0043029 T cell homeostasis(GO:0043029)
0.0 0.5 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 0.2 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.6 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 0.3 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.0 0.1 GO:0000722 telomere maintenance via recombination(GO:0000722)
0.0 0.1 GO:0061002 negative regulation of dendritic spine morphogenesis(GO:0061002)
0.0 0.5 GO:0007520 myoblast fusion(GO:0007520)
0.0 0.8 GO:0008631 intrinsic apoptotic signaling pathway in response to oxidative stress(GO:0008631)
0.0 0.0 GO:1903094 regulation of protein K48-linked deubiquitination(GO:1903093) negative regulation of protein K48-linked deubiquitination(GO:1903094) negative regulation of ubiquitin-specific protease activity(GO:2000157)
0.0 0.2 GO:0043649 dicarboxylic acid catabolic process(GO:0043649)
0.0 0.4 GO:0032469 endoplasmic reticulum calcium ion homeostasis(GO:0032469)
0.0 0.2 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0 0.1 GO:0001955 blood vessel maturation(GO:0001955)
0.0 0.1 GO:0008616 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.0 0.5 GO:0033119 negative regulation of RNA splicing(GO:0033119)
0.0 0.0 GO:1901069 guanosine-containing compound catabolic process(GO:1901069)
0.0 0.1 GO:0000963 mitochondrial RNA processing(GO:0000963)
0.0 0.2 GO:0003283 atrial septum development(GO:0003283)
0.0 0.1 GO:0035330 regulation of hippo signaling(GO:0035330)
0.0 0.1 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.0 0.5 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.0 0.3 GO:1903146 regulation of mitophagy(GO:1903146)
0.0 0.2 GO:0033008 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.0 0.2 GO:0003417 growth plate cartilage development(GO:0003417)
0.0 1.7 GO:1990830 response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.2 GO:0043020 NADPH oxidase complex(GO:0043020)
0.2 0.7 GO:0030312 external encapsulating structure(GO:0030312)
0.2 0.7 GO:0036019 endolysosome(GO:0036019)
0.2 1.7 GO:0005818 aster(GO:0005818)
0.2 0.9 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.2 3.3 GO:0032426 stereocilium tip(GO:0032426)
0.2 1.0 GO:0005826 actomyosin contractile ring(GO:0005826)
0.1 2.0 GO:0042555 MCM complex(GO:0042555)
0.1 1.1 GO:0008278 cohesin complex(GO:0008278)
0.1 0.6 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.1 0.4 GO:0097450 astrocyte end-foot(GO:0097450)
0.1 0.5 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
0.1 4.6 GO:0001772 immunological synapse(GO:0001772)
0.1 0.7 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.1 1.1 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.1 0.3 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.1 0.3 GO:0044307 dendritic branch(GO:0044307)
0.1 0.4 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.1 0.8 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.1 1.3 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.0 2.5 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 1.2 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.2 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 1.6 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 1.5 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.1 GO:0035061 interchromatin granule(GO:0035061)
0.0 0.5 GO:0031209 SCAR complex(GO:0031209)
0.0 0.2 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 0.2 GO:0005927 muscle tendon junction(GO:0005927)
0.0 0.4 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.1 GO:0097543 ciliary inversin compartment(GO:0097543)
0.0 2.4 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.2 GO:0032807 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958) DNA ligase IV complex(GO:0032807)
0.0 0.4 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.1 GO:0099522 region of cytosol(GO:0099522) postsynaptic cytosol(GO:0099524)
0.0 0.4 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.5 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.6 GO:0042588 zymogen granule(GO:0042588)
0.0 1.9 GO:0005581 collagen trimer(GO:0005581)
0.0 0.2 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.7 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.2 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.8 GO:0008180 COP9 signalosome(GO:0008180)
0.0 0.2 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.0 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.0 0.3 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.4 GO:0000800 lateral element(GO:0000800)
0.0 0.0 GO:0070985 TFIIK complex(GO:0070985)
0.0 0.5 GO:0051233 spindle midzone(GO:0051233)
0.0 0.7 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.1 GO:0005642 annulate lamellae(GO:0005642)
0.0 0.3 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.7 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.1 GO:0034709 methylosome(GO:0034709)
0.0 0.1 GO:1990462 omegasome(GO:1990462)
0.0 3.7 GO:0009897 external side of plasma membrane(GO:0009897)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.2 GO:0045353 interleukin-1, Type II receptor binding(GO:0005151) interleukin-1 receptor antagonist activity(GO:0005152) interleukin-1 Type I receptor antagonist activity(GO:0045352) interleukin-1 Type II receptor antagonist activity(GO:0045353)
0.4 1.8 GO:0019770 IgG receptor activity(GO:0019770)
0.3 0.7 GO:0019864 IgG binding(GO:0019864)
0.3 2.0 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.2 1.3 GO:0051425 PTB domain binding(GO:0051425)
0.2 1.6 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.2 0.6 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.2 1.6 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.2 1.7 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.2 0.6 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.2 1.3 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.2 1.4 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.2 3.3 GO:0032036 myosin heavy chain binding(GO:0032036)
0.1 0.9 GO:0019958 C-X-C chemokine binding(GO:0019958)
0.1 0.5 GO:0016997 exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997) exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.1 0.4 GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.1 1.4 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.1 0.6 GO:0097001 ceramide binding(GO:0097001)
0.1 0.7 GO:0001851 complement component C3b binding(GO:0001851)
0.1 0.4 GO:0004566 beta-glucuronidase activity(GO:0004566)
0.1 0.6 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.1 0.3 GO:0004974 leukotriene receptor activity(GO:0004974)
0.1 0.6 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.1 0.5 GO:0001179 RNA polymerase I transcription factor binding(GO:0001179)
0.1 0.6 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.1 0.5 GO:0045322 unmethylated CpG binding(GO:0045322)
0.1 0.4 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.1 0.2 GO:0004051 arachidonate 5-lipoxygenase activity(GO:0004051)
0.1 0.3 GO:0019966 interleukin-1 binding(GO:0019966)
0.1 0.9 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.1 0.6 GO:0003796 lysozyme activity(GO:0003796)
0.1 1.1 GO:0051400 BH domain binding(GO:0051400)
0.1 0.4 GO:0000150 recombinase activity(GO:0000150)
0.1 1.9 GO:0043394 proteoglycan binding(GO:0043394)
0.0 0.6 GO:0001054 RNA polymerase I activity(GO:0001054)
0.0 1.6 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.2 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.1 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.7 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.0 0.1 GO:0031686 A1 adenosine receptor binding(GO:0031686)
0.0 0.5 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.2 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.7 GO:0015299 solute:proton antiporter activity(GO:0015299)
0.0 0.1 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.0 0.6 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.7 GO:0045125 bioactive lipid receptor activity(GO:0045125)
0.0 0.2 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.0 0.2 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.0 0.1 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.0 0.2 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 0.2 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.0 0.6 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.1 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.0 0.2 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.8 GO:0051393 alpha-actinin binding(GO:0051393)
0.0 0.9 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 4.1 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.3 GO:0016624 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor(GO:0016624)
0.0 1.1 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.6 GO:0071949 FAD binding(GO:0071949)
0.0 0.3 GO:0035613 RNA stem-loop binding(GO:0035613)
0.0 0.5 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.1 GO:0004534 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160) 5'-3' exoribonuclease activity(GO:0004534)
0.0 1.2 GO:0001784 phosphotyrosine binding(GO:0001784)
0.0 1.6 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.0 0.1 GO:0032767 copper-dependent protein binding(GO:0032767)
0.0 0.0 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.0 0.1 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.1 GO:0004920 interleukin-10 receptor activity(GO:0004920)
0.0 0.2 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.7 GO:0016278 lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279)
0.0 0.1 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.1 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.3 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.1 GO:0008649 rRNA methyltransferase activity(GO:0008649)
0.0 0.1 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.7 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.3 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.3 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.2 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.3 GO:0042287 MHC protein binding(GO:0042287)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.5 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.1 3.9 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.1 0.7 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 2.3 PID ATR PATHWAY ATR signaling pathway
0.0 0.4 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 1.6 PID AURORA A PATHWAY Aurora A signaling
0.0 1.3 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 1.2 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 2.0 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 0.8 PID IL1 PATHWAY IL1-mediated signaling events
0.0 0.8 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.6 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 1.3 PID P53 REGULATION PATHWAY p53 pathway
0.0 0.9 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.0 1.3 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.1 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 1.2 PID E2F PATHWAY E2F transcription factor network
0.0 0.0 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.7 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 0.5 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.4 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 0.3 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 0.2 PID ATM PATHWAY ATM pathway
0.0 0.1 PID CDC42 REG PATHWAY Regulation of CDC42 activity

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.6 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.2 0.5 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.1 2.0 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.1 1.7 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.1 1.0 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.1 1.5 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.1 3.0 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.1 1.0 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.1 1.4 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.1 3.0 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.1 0.7 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.1 0.4 REACTOME ACYL CHAIN REMODELLING OF PC Genes involved in Acyl chain remodelling of PC
0.1 0.5 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 1.2 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.6 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.9 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 0.4 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 2.7 REACTOME 3 UTR MEDIATED TRANSLATIONAL REGULATION Genes involved in 3' -UTR-mediated translational regulation
0.0 1.2 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 1.1 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.7 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.2 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 0.7 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0 0.2 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.3 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.0 0.2 REACTOME DOUBLE STRAND BREAK REPAIR Genes involved in Double-Strand Break Repair
0.0 0.3 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.8 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.4 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.7 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.2 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.5 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 2.6 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.3 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.2 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.0 1.0 REACTOME GLYCEROPHOSPHOLIPID BIOSYNTHESIS Genes involved in Glycerophospholipid biosynthesis