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2D miR_HR1_12

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Results for Irf4

Z-value: 0.59

Motif logo

Transcription factors associated with Irf4

Gene Symbol Gene ID Gene Info
ENSMUSG00000021356.3 interferon regulatory factor 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Irf4mm10_v2_chr13_+_30749226_30749247-0.401.9e-01Click!

Activity profile of Irf4 motif

Sorted Z-values of Irf4 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr11_+_69966896 1.22 ENSMUST00000151515.1
claudin 7
chr1_+_16688405 1.18 ENSMUST00000026881.4
lymphocyte antigen 96
chr2_-_152831112 0.73 ENSMUST00000128172.1
BCL2-like 1
chr19_-_58454580 0.69 ENSMUST00000129100.1
ENSMUST00000123957.1
glial cell line derived neurotrophic factor family receptor alpha 1
chrX_-_134161928 0.64 ENSMUST00000033611.4
X Kell blood group precursor related X linked
chr19_+_34640871 0.58 ENSMUST00000102824.3
interferon-induced protein with tetratricopeptide repeats 1
chr8_-_35826435 0.58 ENSMUST00000060128.5
claudin 23
chr17_-_28915314 0.52 ENSMUST00000062357.4
RIKEN cDNA 4930539E08 gene
chr3_+_138065052 0.52 ENSMUST00000163080.2
RIKEN cDNA 1110002E22 gene
chr18_+_37484955 0.52 ENSMUST00000053856.4
protocadherin beta 17
chr3_+_3634145 0.48 ENSMUST00000108394.1
hepatocyte nuclear factor 4, gamma
chr4_-_89311021 0.48 ENSMUST00000097981.4
cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
chr19_-_58455398 0.46 ENSMUST00000026076.7
glial cell line derived neurotrophic factor family receptor alpha 1
chr15_-_66560997 0.46 ENSMUST00000048372.5
transmembrane protein 71
chr6_+_96115249 0.45 ENSMUST00000075080.5
family with sequence similarity 19, member A1
chr5_+_102481374 0.44 ENSMUST00000094559.2
ENSMUST00000073302.5
Rho GTPase activating protein 24
chr19_-_58455161 0.43 ENSMUST00000135730.1
ENSMUST00000152507.1
glial cell line derived neurotrophic factor family receptor alpha 1
chr1_-_174921813 0.43 ENSMUST00000055294.3
gremlin 2 homolog, cysteine knot superfamily (Xenopus laevis)
chr9_+_99470440 0.42 ENSMUST00000056103.4
RIKEN cDNA 1600029I14 gene
chr3_+_3508024 0.41 ENSMUST00000108393.1
ENSMUST00000017832.8
hepatocyte nuclear factor 4, gamma
chr17_+_8849974 0.41 ENSMUST00000115720.1
phosphodiesterase 10A
chr2_-_152830615 0.39 ENSMUST00000146380.1
ENSMUST00000134902.1
ENSMUST00000134357.1
ENSMUST00000109820.3
BCL2-like 1
chr5_+_102481546 0.38 ENSMUST00000112854.1
Rho GTPase activating protein 24
chr14_-_66124482 0.37 ENSMUST00000070515.1
epoxide hydrolase 2, cytoplasmic
chr10_-_64090265 0.35 ENSMUST00000105439.1
leucine rich repeat transmembrane neuronal 3
chr14_+_60732906 0.34 ENSMUST00000162945.1
spermatogenesis associated 13
chr10_+_69212676 0.33 ENSMUST00000167384.1
Rho-related BTB domain containing 1
chr3_-_108200807 0.33 ENSMUST00000106655.1
ENSMUST00000065664.6
cytochrome b-561 domain containing 1
chr14_+_65266701 0.33 ENSMUST00000169656.1
F-box protein 16
chr19_+_8850785 0.32 ENSMUST00000096257.2
LRRN4 C-terminal like
chrX_+_136707976 0.32 ENSMUST00000055104.5
transcription elongation factor A (SII)-like 1
chr16_-_52454074 0.32 ENSMUST00000023312.7
activated leukocyte cell adhesion molecule
chr2_+_128126030 0.29 ENSMUST00000089634.5
ENSMUST00000019281.7
ENSMUST00000110341.2
ENSMUST00000103211.1
ENSMUST00000103210.1
BCL2-like 11 (apoptosis facilitator)
chr5_+_147269959 0.29 ENSMUST00000085591.5
pancreatic and duodenal homeobox 1
chr18_+_37264998 0.29 ENSMUST00000052366.3
protocadherin beta 1
chr12_-_79007276 0.29 ENSMUST00000056660.6
ENSMUST00000174721.1
transmembrane protein 229B
chr3_+_89421619 0.28 ENSMUST00000094378.3
ENSMUST00000137793.1
src homology 2 domain-containing transforming protein C1
chr10_+_69212634 0.27 ENSMUST00000020101.5
Rho-related BTB domain containing 1
chr10_+_128706251 0.27 ENSMUST00000054125.8
premelanosome protein
chr7_+_4460687 0.26 ENSMUST00000167298.1
ENSMUST00000171445.1
EPS8-like 1
chr18_+_82855894 0.26 ENSMUST00000181345.1
ENSMUST00000180631.1
RIKEN cDNA 4930445N18 gene
chr4_-_133263042 0.26 ENSMUST00000105908.3
ENSMUST00000030674.7
synaptotagmin-like 1
chr10_+_86022189 0.25 ENSMUST00000120344.1
ENSMUST00000117597.1
F-box protein 7
chr13_+_23555023 0.25 ENSMUST00000045301.6
histone cluster 1, H1d
chr1_-_93101854 0.24 ENSMUST00000171796.1
ENSMUST00000171556.1
kinesin family member 1A
chr4_-_46536134 0.24 ENSMUST00000046897.6
tripartite motif-containing 14
chr8_+_61928081 0.23 ENSMUST00000154398.1
ENSMUST00000093485.2
ENSMUST00000156980.1
ENSMUST00000070631.7
DEAD (Asp-Glu-Ala-Asp) box polypeptide 60
chrX_-_101222426 0.23 ENSMUST00000120389.1
ENSMUST00000156473.1
ENSMUST00000077876.3
sorting nexin 12
chr12_-_26456423 0.22 ENSMUST00000020970.7
radical S-adenosyl methionine domain containing 2
chr4_-_129239165 0.22 ENSMUST00000097873.3
expressed sequence C77080
chr11_+_43474276 0.21 ENSMUST00000173002.1
ENSMUST00000057679.3
C1q and tumor necrosis factor related protein 2
chr5_-_104021799 0.21 ENSMUST00000119025.1
hydroxysteroid (17-beta) dehydrogenase 11
chr1_+_188263034 0.21 ENSMUST00000060479.7
Usher syndrome 2A (autosomal recessive, mild)
chr6_-_97060407 0.21 ENSMUST00000089295.4
family with sequence similarity 19, member A4
chr9_-_111057235 0.20 ENSMUST00000111888.1
chemokine (C-C motif) receptor-like 2
chr9_+_98864767 0.19 ENSMUST00000167951.1
RIKEN cDNA 2410012M07 gene
chr10_-_86022325 0.19 ENSMUST00000181665.1
RIKEN cDNA A230060F14 gene
chr7_+_58658181 0.19 ENSMUST00000168747.1
ATPase, class V, type 10A
chr19_-_57197556 0.19 ENSMUST00000099294.2
actin-binding LIM protein 1
chr19_+_5568002 0.19 ENSMUST00000096318.3
adaptor-related protein complex 5, beta 1 subunit
chr6_-_39118211 0.18 ENSMUST00000038398.6
poly (ADP-ribose) polymerase family, member 12
chr2_+_23069057 0.18 ENSMUST00000114526.1
ENSMUST00000114529.2
acyl-Coenzyme A binding domain containing 5
chr1_-_93101825 0.18 ENSMUST00000112958.2
kinesin family member 1A
chr13_-_23710714 0.18 ENSMUST00000091707.6
ENSMUST00000006787.7
ENSMUST00000091706.6
hemochromatosis
chrX_-_9469288 0.17 ENSMUST00000015484.3
cytochrome b-245, beta polypeptide
chr7_-_80387935 0.17 ENSMUST00000080932.6
feline sarcoma oncogene
chr2_-_127788854 0.17 ENSMUST00000028857.7
ENSMUST00000110357.1
nephronophthisis 1 (juvenile) homolog (human)
chr4_-_46536096 0.17 ENSMUST00000102924.2
tripartite motif-containing 14
chr5_-_104021919 0.17 ENSMUST00000031251.9
hydroxysteroid (17-beta) dehydrogenase 11
chr12_+_52699297 0.16 ENSMUST00000095737.3
A kinase (PRKA) anchor protein 6
chr19_+_47937648 0.16 ENSMUST00000066308.7
coiled-coil domain containing 147
chr3_+_90537306 0.16 ENSMUST00000107335.1
S100 calcium binding protein A16
chr16_-_24393588 0.15 ENSMUST00000181640.1
RIKEN cDNA 1110054M08 gene
chr6_+_71282280 0.15 ENSMUST00000080949.7
lysine-rich coiled-coil 1
chr2_-_51934644 0.15 ENSMUST00000165313.1
RNA binding motif protein 43
chr10_+_39612934 0.15 ENSMUST00000019987.6
TRAF3 interacting protein 2
chr17_-_6782775 0.15 ENSMUST00000064234.6
ezrin
chr19_+_34607927 0.15 ENSMUST00000076249.5
RIKEN cDNA I830012O16 gene
chr11_+_115462464 0.14 ENSMUST00000106532.3
ENSMUST00000092445.5
ENSMUST00000153466.1
solute carrier family 16 (monocarboxylic acid transporters), member 5
chr11_-_107470699 0.14 ENSMUST00000103064.3
phosphatidylinositol transfer protein, cytoplasmic 1
chr11_+_82115180 0.14 ENSMUST00000009329.2
chemokine (C-C motif) ligand 8
chr2_+_71453276 0.14 ENSMUST00000037210.8
methionyl aminopeptidase type 1D (mitochondrial)
chr1_-_161876656 0.14 ENSMUST00000048377.5
SUN domain containing ossification factor
chr11_-_101171302 0.13 ENSMUST00000164474.1
ENSMUST00000043397.7
pleckstrin homology domain containing, family H (with MyTH4 domain) member 3
chr9_+_5345414 0.13 ENSMUST00000027009.4
caspase 12
chr16_+_24393350 0.13 ENSMUST00000038053.6
LIM domain containing preferred translocation partner in lipoma
chr3_+_142496924 0.12 ENSMUST00000090127.2
guanylate binding protein 5
chr14_-_54409469 0.12 ENSMUST00000000984.4
solute carrier family 7 (cationic amino acid transporter, y+ system), member 7
chr9_-_116175318 0.12 ENSMUST00000061101.4
ENSMUST00000035014.6
transforming growth factor, beta receptor II
chr10_-_24109582 0.11 ENSMUST00000041180.5
trace amine-associated receptor 9
chr3_+_95526777 0.11 ENSMUST00000015667.2
ENSMUST00000116304.2
cathepsin S
chr14_-_79223876 0.10 ENSMUST00000040802.4
zinc finger protein 957
chrX_+_20848543 0.10 ENSMUST00000001155.4
ENSMUST00000122312.1
ENSMUST00000120356.1
ENSMUST00000122850.1
v-raf murine sarcoma 3611 viral oncogene homolog
chr7_-_141266415 0.10 ENSMUST00000106023.1
ENSMUST00000097952.2
ENSMUST00000026571.4
interferon regulatory factor 7
chr1_-_14310198 0.10 ENSMUST00000168081.2
ENSMUST00000027066.6
eyes absent 1 homolog (Drosophila)
chr17_+_34203527 0.09 ENSMUST00000025197.5
transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
chr13_-_107890059 0.09 ENSMUST00000105097.2
zinc finger SWIM-type containing 6
chr1_+_57845534 0.09 ENSMUST00000169772.1
spermatogenesis associated, serine-rich 2-like
chr16_+_35938972 0.09 ENSMUST00000023622.6
ENSMUST00000114877.1
poly (ADP-ribose) polymerase family, member 9
chr7_+_35802593 0.09 ENSMUST00000052454.2
RIKEN cDNA E130304I02 gene
chr13_-_19395728 0.09 ENSMUST00000039694.7
STARD3 N-terminal like
chr15_+_52295509 0.09 ENSMUST00000037240.2
solute carrier family 30 (zinc transporter), member 8
chr19_-_57197435 0.09 ENSMUST00000111550.1
actin-binding LIM protein 1
chr1_-_97977233 0.09 ENSMUST00000161567.1
peptidylglycine alpha-amidating monooxygenase
chrX_+_139563316 0.09 ENSMUST00000113027.1
ring finger protein 128
chr2_+_23069210 0.09 ENSMUST00000155602.1
acyl-Coenzyme A binding domain containing 5
chr7_+_78914216 0.08 ENSMUST00000120331.2
interferon-stimulated protein
chr11_+_78245743 0.08 ENSMUST00000002133.8
stromal cell derived factor 2
chr8_+_88651341 0.08 ENSMUST00000109634.2
nucleotide-binding oligomerization domain containing 2
chr9_+_65346066 0.08 ENSMUST00000048184.2
programmed cell death 7
chr8_+_90828820 0.08 ENSMUST00000109614.2
ENSMUST00000048665.6
chromodomain helicase DNA binding protein 9
chr3_+_90537242 0.08 ENSMUST00000098911.3
S100 calcium binding protein A16
chr7_-_16286744 0.08 ENSMUST00000150528.2
ENSMUST00000118976.2
ENSMUST00000146609.2
coiled-coil domain containing 9
chr11_+_46810792 0.08 ENSMUST00000068877.6
T cell immunoglobulin and mucin domain containing 4
chr3_+_152346465 0.08 ENSMUST00000026507.6
ENSMUST00000117492.2
ubiquitin specific peptidase 33
chr13_-_100616911 0.08 ENSMUST00000168772.1
ENSMUST00000163163.1
ENSMUST00000022137.7
MARVEL (membrane-associating) domain containing 2
chr19_+_34583528 0.08 ENSMUST00000102825.3
interferon-induced protein with tetratricopeptide repeats 3
chr13_-_113046357 0.07 ENSMUST00000022282.3
glutathione peroxidase 8 (putative)
chr1_-_184732444 0.07 ENSMUST00000174257.1
H2.0-like homeobox
chr9_+_45042425 0.07 ENSMUST00000034600.4
myelin protein zero-like 2
chr1_-_184732616 0.06 ENSMUST00000048572.6
H2.0-like homeobox
chr6_-_129100903 0.06 ENSMUST00000032258.6
C-type lectin domain family 2, member e
chr12_+_111417430 0.06 ENSMUST00000072646.6
exocyst complex component 3-like 4
chr10_-_41490335 0.05 ENSMUST00000019965.6
sphingomyelin phosphodiesterase 2, neutral
chr1_+_61638819 0.05 ENSMUST00000138768.1
ENSMUST00000075374.3
par-3 partitioning defective 3 homolog B (C. elegans)
chr7_+_19024364 0.05 ENSMUST00000023882.7
symplekin
chr1_-_156939387 0.04 ENSMUST00000171292.1
Ral GEF with PH domain and SH3 binding motif 2
chr1_+_187215737 0.04 ENSMUST00000160471.1
G patch domain containing 2
chrX_+_49463926 0.04 ENSMUST00000130558.1
Rho GTPase activating protein 36
chr19_+_56397100 0.04 ENSMUST00000026062.9
caspase 7
chr13_+_5861489 0.04 ENSMUST00000000080.6
Kruppel-like factor 6
chr10_+_21882184 0.04 ENSMUST00000120509.1
serum/glucocorticoid regulated kinase 1
chr3_-_30699843 0.04 ENSMUST00000108263.1
leucine rich repeat containing 31
chr16_-_26371828 0.03 ENSMUST00000023154.2
claudin 1
chr1_+_82724881 0.03 ENSMUST00000078332.6
mitochondrial fission factor
chr11_+_65162132 0.03 ENSMUST00000181156.1
RIKEN cDNA B430202K04 gene
chr16_-_55838827 0.03 ENSMUST00000096026.2
ENSMUST00000036273.6
ENSMUST00000114457.1
nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, zeta
chr19_+_46623387 0.03 ENSMUST00000111855.4
WW domain binding protein 1 like
chr19_-_57197377 0.03 ENSMUST00000111546.1
actin-binding LIM protein 1
chr19_-_57197496 0.03 ENSMUST00000111544.1
actin-binding LIM protein 1
chr13_+_42052015 0.03 ENSMUST00000060148.5
human immunodeficiency virus type I enhancer binding protein 1
chr8_-_125492710 0.03 ENSMUST00000108775.1
signal-induced proliferation-associated 1 like 2
chr11_+_49087022 0.03 ENSMUST00000046704.6
interferon gamma inducible protein 47
chr7_+_19024387 0.02 ENSMUST00000153976.1
symplekin
chr2_-_72813665 0.02 ENSMUST00000136807.1
ENSMUST00000148327.1
RIKEN cDNA 6430710C18 gene
chr13_+_20090500 0.02 ENSMUST00000165249.2
engulfment and cell motility 1
chr11_-_120348513 0.02 ENSMUST00000071555.6
actin, gamma, cytoplasmic 1
chr4_-_4138817 0.02 ENSMUST00000133567.1
preproenkephalin
chr2_-_131175201 0.02 ENSMUST00000110218.2
sperm flagellar 1
chr10_-_107719978 0.02 ENSMUST00000050702.7
protein tyrosine phosphatase, receptor type, Q
chr11_+_78343475 0.02 ENSMUST00000002127.7
ENSMUST00000108295.1
unc-119 homolog (C. elegans)
chr10_+_94575257 0.01 ENSMUST00000121471.1
transmembrane and coiled coil domains 3
chr1_-_84935089 0.01 ENSMUST00000027422.5
solute carrier family 16 (monocarboxylic acid transporters), member 14
chr17_+_34564268 0.01 ENSMUST00000015612.7
notch 4
chr10_-_52195244 0.01 ENSMUST00000020045.3
Ros1 proto-oncogene
chr11_+_119393060 0.01 ENSMUST00000131035.2
ENSMUST00000093902.5
ring finger protein 213
chr7_+_127296251 0.00 ENSMUST00000117762.1
integrin alpha L
chr12_-_4477138 0.00 ENSMUST00000085814.3
nuclear receptor coactivator 1
chr1_+_66468364 0.00 ENSMUST00000061620.9
unc-80 homolog (C. elegans)
chr16_+_25801907 0.00 ENSMUST00000040231.6
ENSMUST00000115306.1
ENSMUST00000115304.1
ENSMUST00000115305.1
transformation related protein 63
chr11_+_67321638 0.00 ENSMUST00000108684.1
myosin, heavy polypeptide 13, skeletal muscle
chr5_-_66514815 0.00 ENSMUST00000161879.1
ENSMUST00000159357.1
amyloid beta (A4) precursor protein-binding, family B, member 2
chr7_+_127296291 0.00 ENSMUST00000106306.2
ENSMUST00000120857.1
integrin alpha L

Network of associatons between targets according to the STRING database.

First level regulatory network of Irf4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.1 GO:0046898 response to cycloheximide(GO:0046898)
0.2 1.2 GO:0032497 detection of lipopolysaccharide(GO:0032497)
0.1 0.4 GO:0060300 regulation of cytokine activity(GO:0060300)
0.1 0.4 GO:0006710 androgen catabolic process(GO:0006710)
0.1 0.4 GO:0046271 phenylpropanoid catabolic process(GO:0046271) olefin metabolic process(GO:1900673)
0.1 0.8 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.1 0.2 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.1 0.2 GO:2000642 negative regulation of early endosome to late endosome transport(GO:2000642)
0.1 0.2 GO:0034165 positive regulation of toll-like receptor 9 signaling pathway(GO:0034165)
0.1 0.3 GO:0060154 cellular process regulating host cell cycle in response to virus(GO:0060154)
0.1 0.2 GO:1903348 positive regulation of bicellular tight junction assembly(GO:1903348)
0.1 1.2 GO:0032463 negative regulation of protein homooligomerization(GO:0032463)
0.1 0.3 GO:0009730 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.1 0.3 GO:1990839 response to endothelin(GO:1990839)
0.1 0.3 GO:0002589 regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589)
0.0 0.1 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
0.0 0.7 GO:0035457 cellular response to interferon-alpha(GO:0035457)
0.0 0.4 GO:1902004 positive regulation of beta-amyloid formation(GO:1902004)
0.0 0.1 GO:0032499 detection of peptidoglycan(GO:0032499)
0.0 0.2 GO:0048496 maintenance of organ identity(GO:0048496)
0.0 0.2 GO:2000481 positive regulation of cAMP-dependent protein kinase activity(GO:2000481)
0.0 0.1 GO:0000821 regulation of arginine metabolic process(GO:0000821)
0.0 0.1 GO:0003274 endocardial cushion fusion(GO:0003274) positive regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000563)
0.0 0.3 GO:0030242 pexophagy(GO:0030242)
0.0 0.2 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.5 GO:0060253 negative regulation of glial cell proliferation(GO:0060253)
0.0 0.3 GO:1903208 neuron death in response to hydrogen peroxide(GO:0036476) regulation of hydrogen peroxide-induced neuron death(GO:1903207) negative regulation of hydrogen peroxide-induced neuron death(GO:1903208)
0.0 0.3 GO:0048023 positive regulation of melanin biosynthetic process(GO:0048023) positive regulation of secondary metabolite biosynthetic process(GO:1900378)
0.0 0.1 GO:0034769 basement membrane disassembly(GO:0034769)
0.0 0.4 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.1 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.0 0.3 GO:1900029 positive regulation of ruffle assembly(GO:1900029)
0.0 0.4 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.2 GO:0097411 hypoxia-inducible factor-1alpha signaling pathway(GO:0097411)
0.0 0.1 GO:0034124 regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124)
0.0 0.1 GO:1900227 positive regulation of NLRP3 inflammasome complex assembly(GO:1900227)
0.0 0.1 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.0 0.3 GO:0032897 negative regulation of viral transcription(GO:0032897)
0.0 0.0 GO:0072733 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.2 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.1 1.4 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.1 0.3 GO:0032585 multivesicular body membrane(GO:0032585)
0.1 0.2 GO:1990696 USH2 complex(GO:1990696)
0.1 0.3 GO:1990037 Lewy body core(GO:1990037)
0.0 0.1 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.0 0.2 GO:1990357 terminal web(GO:1990357)
0.0 0.6 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.2 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.1 GO:0033010 paranodal junction(GO:0033010)
0.0 0.1 GO:0042825 TAP complex(GO:0042825)
0.0 0.3 GO:0042101 T cell receptor complex(GO:0042101)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.2 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.1 1.1 GO:0051434 BH3 domain binding(GO:0051434)
0.1 0.4 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.1 0.3 GO:0048408 epidermal growth factor binding(GO:0048408)
0.1 0.4 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.0 0.4 GO:0036122 BMP binding(GO:0036122)
0.0 0.4 GO:0004303 estradiol 17-beta-dehydrogenase activity(GO:0004303)
0.0 0.5 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.1 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.0 0.2 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.1 GO:0016715 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715) amidine-lyase activity(GO:0016842)
0.0 0.2 GO:0039706 co-receptor binding(GO:0039706)
0.0 0.1 GO:0008859 exoribonuclease II activity(GO:0008859)
0.0 0.1 GO:0046980 peptide antigen-transporting ATPase activity(GO:0015433) tapasin binding(GO:0046980)
0.0 0.6 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.1 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.1 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.2 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 0.3 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.0 0.1 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.3 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.1 GO:0097153 cysteine-type endopeptidase activity involved in apoptotic process(GO:0097153)
0.0 0.9 GO:0098531 RNA polymerase II transcription factor activity, ligand-activated sequence-specific DNA binding(GO:0004879) transcription factor activity, direct ligand regulated sequence-specific DNA binding(GO:0098531)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.4 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 1.2 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 1.9 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.1 1.1 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.0 0.1 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 1.2 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 1.3 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 1.6 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.2 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.3 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.2 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.4 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.3 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.3 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.5 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.4 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.1 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon