Project

2D miR_HR1_12

Navigation
Downloads

Results for Rest

Z-value: 1.28

Motif logo

Transcription factors associated with Rest

Gene Symbol Gene ID Gene Info
ENSMUSG00000029249.9 RE1-silencing transcription factor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Restmm10_v2_chr5_+_77266196_772662320.058.8e-01Click!

Activity profile of Rest motif

Sorted Z-values of Rest motif

Promoter Log-likelihood Transcript Gene Gene Info
chr16_-_23890805 6.82 ENSMUST00000004480.3
somatostatin
chr15_-_76521902 4.74 ENSMUST00000164703.1
ENSMUST00000096365.3
scratch homolog 1, zinc finger protein (Drosophila)
chr12_-_84698769 3.19 ENSMUST00000095550.2
synapse differentiation inducing 1 like
chr10_+_5639210 3.08 ENSMUST00000019906.4
vasoactive intestinal polypeptide
chr5_+_137030275 2.98 ENSMUST00000041543.8
VGF nerve growth factor inducible
chr19_+_42255704 2.93 ENSMUST00000087123.5
golgi autoantigen, golgin subfamily a, 7B
chrX_-_73869804 2.52 ENSMUST00000066576.5
ENSMUST00000114430.1
L1 cell adhesion molecule
chr9_+_59578192 2.29 ENSMUST00000118549.1
ENSMUST00000034840.3
CUGBP, Elav-like family member 6
chr3_+_114904062 2.19 ENSMUST00000081752.6
olfactomedin 3
chr13_-_99900645 2.19 ENSMUST00000022150.6
CART prepropeptide
chr1_-_84696182 2.11 ENSMUST00000049126.6
delta/notch-like EGF-related receptor
chr12_-_112511136 2.05 ENSMUST00000066791.5
transmembrane protein 179
chr2_-_181314500 1.89 ENSMUST00000103045.3
stathmin-like 3
chr8_+_84946987 1.78 ENSMUST00000067472.7
ENSMUST00000109740.2
retbindin
chr17_+_28575718 1.53 ENSMUST00000080780.6
lipoma HMGIC fusion partner-like 5
chr5_-_116591811 1.34 ENSMUST00000076124.5
serine/arginine repetitive matrix 4
chr2_+_132781278 1.32 ENSMUST00000028826.3
chromogranin B
chr9_+_104569671 1.29 ENSMUST00000057742.8
copine IV
chr9_+_104569754 1.28 ENSMUST00000077190.6
copine IV
chr16_+_30065333 1.26 ENSMUST00000023171.7
hairy and enhancer of split 1 (Drosophila)
chr17_+_69439326 1.20 ENSMUST00000169935.1
RIKEN cDNA A330050F15 gene
chr17_-_91092715 1.19 ENSMUST00000160800.2
ENSMUST00000159778.1
ENSMUST00000160844.3
neurexin I
chr15_-_75747922 1.00 ENSMUST00000062002.4
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein A (avian)
chr19_-_8929323 0.99 ENSMUST00000096242.3
rod outer segment membrane protein 1
chr15_+_101473472 0.93 ENSMUST00000088049.3
keratin 86
chr2_+_152143552 0.90 ENSMUST00000089112.5
transcription factor 15
chr1_+_34579693 0.82 ENSMUST00000052670.8
APC membrane recruitment 3
chr19_-_45046614 0.80 ENSMUST00000145391.1
PDZ domain containing 7
chr7_-_27396542 0.80 ENSMUST00000108363.1
spectrin beta, non-erythrocytic 4
chrX_-_20920911 0.76 ENSMUST00000081893.6
ENSMUST00000115345.1
synapsin I
chr17_-_25240112 0.74 ENSMUST00000038973.6
ENSMUST00000115154.4
N-acetylglucosamine-1-phosphotransferase, gamma subunit
chr6_-_121473630 0.73 ENSMUST00000046373.5
IQ motif and Sec7 domain 3
chr12_+_113140198 0.72 ENSMUST00000084882.4
cysteine rich protein 2
chr9_-_63146980 0.55 ENSMUST00000055281.7
ENSMUST00000119146.1
SKI family transcriptional corepressor 1
chr15_-_76722161 0.52 ENSMUST00000049956.4
leucine rich repeat containing 24
chr8_+_69088646 0.51 ENSMUST00000006435.7
ATPase, H+ transporting, lysosomal V1 subunit B2
chr12_-_70347536 0.47 ENSMUST00000110520.2
ENSMUST00000110522.2
ENSMUST00000167755.1
tripartite motif-containing 9
chr17_-_72603709 0.44 ENSMUST00000086639.4
anaplastic lymphoma kinase
chr19_+_22139028 0.41 ENSMUST00000099569.2
ENSMUST00000087576.4
ENSMUST00000074770.5
transient receptor potential cation channel, subfamily M, member 3
chr2_+_157456917 0.40 ENSMUST00000109529.1
Rous sarcoma oncogene
chr13_+_54371340 0.37 ENSMUST00000026985.8
complexin 2
chr11_+_69914179 0.37 ENSMUST00000057884.5
G protein pathway suppressor 2
chr11_-_3774706 0.36 ENSMUST00000155197.1
oxysterol binding protein 2
chr6_+_117168535 0.32 ENSMUST00000112866.1
ENSMUST00000112871.1
ENSMUST00000073043.4
chemokine (C-X-C motif) ligand 12
chr13_-_105054895 0.32 ENSMUST00000063551.5
regulator of G-protein signalling 7 binding protein
chr12_+_102554966 0.31 ENSMUST00000021610.5
chromogranin A
chr11_-_117873433 0.30 ENSMUST00000033230.7
threonine aldolase 1
chr9_+_122117338 0.24 ENSMUST00000120173.1
ENSMUST00000134949.1
ENSMUST00000119215.1
SNF related kinase
chr9_+_122117375 0.23 ENSMUST00000118886.1
SNF related kinase
chr17_-_23740301 0.23 ENSMUST00000024702.3
progestin and adipoQ receptor family member IV
chr3_+_100426405 0.21 ENSMUST00000147951.1
ENSMUST00000152827.1
RIKEN cDNA 4930406D18 gene
chr3_-_89764581 0.20 ENSMUST00000029562.3
cholinergic receptor, nicotinic, beta polypeptide 2 (neuronal)
chr7_-_81493883 0.18 ENSMUST00000082090.7
adaptor-related protein complex 3, beta 2 subunit
chr7_+_122671401 0.15 ENSMUST00000182095.1
calcium channel, voltage-dependent, gamma subunit 3
chr8_+_55940453 0.13 ENSMUST00000000275.7
glycine receptor, alpha 3 subunit
chr11_-_55608189 0.13 ENSMUST00000102716.3
glycine receptor, alpha 1 subunit
chr2_+_22622183 0.13 ENSMUST00000028123.3
glutamic acid decarboxylase 2
chr11_-_55607733 0.12 ENSMUST00000108853.1
ENSMUST00000075603.4
glycine receptor, alpha 1 subunit
chr1_+_81077274 0.12 ENSMUST00000068275.5
ENSMUST00000113494.2
neuronal tyrosine-phophorylated phosphoinositide 3-kinase adaptor 2
chr1_+_81077204 0.11 ENSMUST00000123720.1
neuronal tyrosine-phophorylated phosphoinositide 3-kinase adaptor 2
chr9_-_57467985 0.10 ENSMUST00000046587.6
secretory carrier membrane protein 5
chr4_+_15881255 0.07 ENSMUST00000029876.1
calbindin 1
chr11_+_80477015 0.06 ENSMUST00000053413.10
ENSMUST00000147694.1
cyclin-dependent kinase 5, regulatory subunit 1 (p35)
chr5_+_27841947 0.04 ENSMUST00000036227.5
5-hydroxytryptamine (serotonin) receptor 5A
chr1_-_92902883 0.02 ENSMUST00000160548.1
ENSMUST00000112998.1
ankyrin repeat and MYND domain containing 1
chr11_+_74619594 0.02 ENSMUST00000100866.2
RIKEN cDNA E130309D14 gene
chrX_+_7638674 0.01 ENSMUST00000128890.1
synaptophysin

Network of associatons between targets according to the STRING database.

First level regulatory network of Rest

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.2 GO:0070093 negative regulation of glucagon secretion(GO:0070093)
0.6 3.1 GO:0010578 regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579)
0.4 1.3 GO:2000978 trochlear nerve development(GO:0021558) negative regulation of forebrain neuron differentiation(GO:2000978)
0.3 1.2 GO:0090126 protein complex assembly involved in synapse maturation(GO:0090126)
0.3 2.9 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.2 0.7 GO:0016256 N-glycan processing to lysosome(GO:0016256)
0.2 3.0 GO:0043084 penile erection(GO:0043084)
0.2 2.5 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
0.2 1.9 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.1 2.1 GO:0007220 Notch receptor processing(GO:0007220)
0.1 2.3 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.1 0.3 GO:1901079 positive regulation of relaxation of muscle(GO:1901079)
0.1 0.8 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.1 0.9 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.1 4.7 GO:2001222 regulation of neuron migration(GO:2001222)
0.1 0.3 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
0.1 0.4 GO:0051902 negative regulation of mitochondrial depolarization(GO:0051902)
0.1 2.3 GO:0071625 vocalization behavior(GO:0071625)
0.1 0.3 GO:0006566 threonine metabolic process(GO:0006566)
0.1 0.2 GO:0060084 synaptic transmission involved in micturition(GO:0060084)
0.1 0.5 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.1 0.3 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.0 3.2 GO:0001754 eye photoreceptor cell differentiation(GO:0001754)
0.0 0.8 GO:0097091 synaptic vesicle clustering(GO:0097091)
0.0 0.1 GO:0097688 glutamate receptor clustering(GO:0097688)
0.0 1.0 GO:0007263 nitric oxide mediated signal transduction(GO:0007263)
0.0 0.4 GO:0060159 regulation of dopamine receptor signaling pathway(GO:0060159)
0.0 0.1 GO:0006538 glutamate catabolic process(GO:0006538)
0.0 0.7 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 1.3 GO:0000381 regulation of alternative mRNA splicing, via spliceosome(GO:0000381)
0.0 0.4 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
0.0 0.1 GO:0035502 metanephric part of ureteric bud development(GO:0035502) distal convoluted tubule development(GO:0072025) metanephric distal convoluted tubule development(GO:0072221) metanephric distal tubule development(GO:0072235)
0.0 0.5 GO:0015991 ATP hydrolysis coupled proton transport(GO:0015991)
0.0 0.1 GO:0007158 neuron cell-cell adhesion(GO:0007158)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.8 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.2 2.9 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.2 0.8 GO:1990696 USH2 complex(GO:1990696)
0.2 2.4 GO:0044294 dendritic growth cone(GO:0044294)
0.1 0.8 GO:0008091 spectrin(GO:0008091)
0.1 0.4 GO:0070033 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
0.1 1.5 GO:0032426 stereocilium tip(GO:0032426)
0.1 1.0 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.1 1.2 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.1 0.3 GO:0042583 chromaffin granule(GO:0042583)
0.0 0.5 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.9 GO:0045095 keratin filament(GO:0045095)
0.0 1.6 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 1.1 GO:0060077 inhibitory synapse(GO:0060077)
0.0 2.6 GO:0030667 secretory granule membrane(GO:0030667)
0.0 0.1 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.0 0.8 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.2 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 3.5 GO:0030141 secretory granule(GO:0030141)
0.0 1.3 GO:0016363 nuclear matrix(GO:0016363)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0071820 N-box binding(GO:0071820)
0.3 2.5 GO:0033691 sialic acid binding(GO:0033691)
0.2 5.2 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.2 0.7 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.1 9.1 GO:0005179 hormone activity(GO:0005179)
0.1 2.9 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1 0.3 GO:0008732 threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.1 1.2 GO:0097109 neuroligin family protein binding(GO:0097109)
0.1 0.3 GO:0030977 taurine binding(GO:0030977)
0.1 2.1 GO:0005112 Notch binding(GO:0005112)
0.0 0.4 GO:0071253 connexin binding(GO:0071253)
0.0 0.3 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.1 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 0.8 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.7 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.1 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.0 4.7 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 0.2 GO:0042166 acetylcholine-gated cation channel activity(GO:0022848) acetylcholine binding(GO:0042166)
0.0 1.1 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.8 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 0.1 GO:0005499 vitamin D binding(GO:0005499)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.5 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 1.3 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 0.4 ST STAT3 PATHWAY STAT3 Pathway
0.0 2.1 PID NOTCH PATHWAY Notch signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.5 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.1 3.1 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors
0.1 2.1 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.1 0.8 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.0 6.8 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 2.3 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 0.4 REACTOME ADP SIGNALLING THROUGH P2RY1 Genes involved in ADP signalling through P2Y purinoceptor 1
0.0 0.2 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.5 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 0.4 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.0 0.1 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation