Project

2D miR_HR1_12

Navigation
Downloads

Results for Esr1

Z-value: 0.72

Motif logo

Transcription factors associated with Esr1

Gene Symbol Gene ID Gene Info
ENSMUSG00000019768.10 estrogen receptor 1 (alpha)

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Esr1mm10_v2_chr10_+_4611971_4612021-0.801.6e-03Click!

Activity profile of Esr1 motif

Sorted Z-values of Esr1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_9967932 1.33 ENSMUST00000185184.1
transcription factor 24
chr4_+_106733883 1.32 ENSMUST00000047620.2
family with sequence simliarity 151, member A
chr16_+_32756336 1.12 ENSMUST00000135753.1
mucin 4
chr9_+_87144285 1.12 ENSMUST00000113149.1
ENSMUST00000143779.1
ENSMUST00000179313.1
ENSMUST00000049457.7
ENSMUST00000153444.1
melanocortin 2 receptor accessory protein 2
chr4_-_131672133 0.87 ENSMUST00000144212.1
predicted gene 12962
chr7_+_44188205 0.74 ENSMUST00000073713.6
kallikrein 1-related peptidase b24
chr6_-_5496296 0.68 ENSMUST00000019721.4
pyruvate dehydrogenase kinase, isoenzyme 4
chr15_-_95830072 0.64 ENSMUST00000168960.1
predicted gene, 17546
chr11_+_113619318 0.62 ENSMUST00000146390.2
ENSMUST00000106630.1
somatostatin receptor 2
chr12_-_84698769 0.62 ENSMUST00000095550.2
synapse differentiation inducing 1 like
chr11_+_87760533 0.61 ENSMUST00000039627.5
ENSMUST00000100644.3
benzodiazepine receptor associated protein 1
chr7_-_25477607 0.60 ENSMUST00000098669.1
ENSMUST00000098668.1
ENSMUST00000098666.2
carcinoembryonic antigen-related cell adhesion molecule 1
chr7_-_3898120 0.59 ENSMUST00000070639.7
predicted gene 14548
chr2_-_181314500 0.59 ENSMUST00000103045.3
stathmin-like 3
chr1_+_34579693 0.58 ENSMUST00000052670.8
APC membrane recruitment 3
chr15_+_10223974 0.57 ENSMUST00000128450.1
ENSMUST00000148257.1
ENSMUST00000128921.1
prolactin receptor
chr4_-_141825997 0.57 ENSMUST00000102481.3
chymotrypsin-like elastase family, member 2A
chr12_+_31073962 0.55 ENSMUST00000041133.8
family with sequence similarity 110, member C
chr3_-_89089955 0.55 ENSMUST00000166687.1
RUN and SH3 domain containing 1
chr11_-_115808068 0.55 ENSMUST00000132780.1
CASK-interacting protein 2
chrX_-_102906469 0.55 ENSMUST00000120808.1
ENSMUST00000121197.1
DMRT-like family C1a
chr18_+_74442551 0.54 ENSMUST00000121875.1
myosin VB
chr11_+_9048575 0.54 ENSMUST00000043285.4
predicted gene 11992
chr7_-_143074561 0.53 ENSMUST00000148715.1
transient receptor potential cation channel, subfamily M, member 5
chr8_+_114133557 0.52 ENSMUST00000073521.5
ENSMUST00000066514.6
nudix (nucleoside diphosphate linked moiety X)-type motif 7
chr18_+_74442500 0.52 ENSMUST00000074157.6
myosin VB
chr8_+_114133601 0.51 ENSMUST00000109109.1
nudix (nucleoside diphosphate linked moiety X)-type motif 7
chr4_+_143349757 0.50 ENSMUST00000052458.2
leucine rich repeat containing 38
chr8_-_105933832 0.49 ENSMUST00000034368.6
chymotrypsin-like
chr9_+_72925622 0.49 ENSMUST00000038489.5
pygopus 1
chr11_-_31824518 0.48 ENSMUST00000134944.1
RIKEN cDNA D630024D03 gene
chr8_+_114133635 0.48 ENSMUST00000147605.1
ENSMUST00000134593.1
nudix (nucleoside diphosphate linked moiety X)-type motif 7
chr4_-_138367966 0.47 ENSMUST00000030535.3
cytidine deaminase
chr19_+_5406815 0.47 ENSMUST00000174412.1
ENSMUST00000153017.2
RIKEN cDNA 4930481A15 gene
chr6_+_108783059 0.47 ENSMUST00000032196.6
ADP-ribosylation factor-like 8B
chr17_-_54299034 0.47 ENSMUST00000095712.3
solute carrier family 5 (choline transporter), member 7
chr17_+_55970451 0.46 ENSMUST00000044216.6
src homology 2 domain-containing transforming protein D
chr7_+_141461728 0.46 ENSMUST00000167491.1
ENSMUST00000165194.1
EF-hand calcium binding domain 4A
chr10_+_77259280 0.45 ENSMUST00000020493.7
protein O-fucosyltransferase 2
chr10_+_117629493 0.45 ENSMUST00000020399.5
carboxypeptidase M
chr13_+_48513570 0.45 ENSMUST00000065465.1
RIKEN cDNA A830005F24 gene
chr7_+_30977043 0.45 ENSMUST00000058093.4
family with sequence similarity 187, member B
chr1_+_88070765 0.44 ENSMUST00000073772.4
UDP glucuronosyltransferase 1 family, polypeptide A9
chr6_-_65144908 0.44 ENSMUST00000031982.4
hematopoietic prostaglandin D synthase
chr6_-_124733121 0.44 ENSMUST00000112484.3
protein tyrosine phosphatase, non-receptor type 6
chr4_+_46039202 0.44 ENSMUST00000156200.1
tropomodulin 1
chr2_-_3422608 0.43 ENSMUST00000064685.7
meiosis expressed gene 1
chr7_-_104315455 0.43 ENSMUST00000106837.1
ENSMUST00000106839.2
ENSMUST00000070943.6
tripartite motif-containing 12A
chr17_+_37270214 0.43 ENSMUST00000038580.6
histocompatibility 2, M region locus 3
chr7_-_45759527 0.43 ENSMUST00000075571.7
sulfotransferase family, cytosolic, 2B, member 1
chr17_+_8924109 0.43 ENSMUST00000149440.1
phosphodiesterase 10A
chr4_+_152199805 0.43 ENSMUST00000105652.2
acyl-CoA thioesterase 7
chr8_-_70487314 0.42 ENSMUST00000045286.7
transmembrane protein 59-like
chr5_+_149006948 0.42 ENSMUST00000124198.1
predicted gene 15408
chr6_-_85069449 0.42 ENSMUST00000160783.1
ENSMUST00000160197.1
exocyst complex component 6B
chr7_+_46847128 0.41 ENSMUST00000005051.4
lactate dehydrogenase A
chr10_-_86022325 0.41 ENSMUST00000181665.1
RIKEN cDNA A230060F14 gene
chr10_-_9675163 0.41 ENSMUST00000100070.2
sterile alpha motif domain containing 5
chr11_+_120348678 0.41 ENSMUST00000143813.1
RIKEN cDNA 0610009L18 gene
chr9_+_37208291 0.41 ENSMUST00000034632.8
transmembrane protein 218
chr10_-_93081596 0.41 ENSMUST00000168617.1
ENSMUST00000168110.1
ENSMUST00000020200.7
RIKEN cDNA 4930485B16 gene
chr7_-_79848191 0.41 ENSMUST00000107392.1
alanyl (membrane) aminopeptidase
chr6_+_138140521 0.40 ENSMUST00000120939.1
ENSMUST00000120302.1
microsomal glutathione S-transferase 1
chr6_-_112388013 0.40 ENSMUST00000060847.5
ssu-2 homolog (C. elegans)
chr11_+_16752203 0.40 ENSMUST00000102884.3
ENSMUST00000020329.6
epidermal growth factor receptor
chr2_-_6212979 0.40 ENSMUST00000114941.1
enoyl Coenzyme A hydratase domain containing 3
chr4_-_148151878 0.39 ENSMUST00000105706.1
ENSMUST00000030858.7
ENSMUST00000134261.1
F-box protein 6
chr18_-_32139570 0.39 ENSMUST00000171765.1
protein C
chr9_-_62510498 0.39 ENSMUST00000164246.2
coronin, actin binding protein, 2B
chr15_+_89076124 0.39 ENSMUST00000165690.1
TraB domain containing
chrX_-_104857228 0.39 ENSMUST00000033575.5
melanoma antigen, family E, 2
chr17_-_37280418 0.39 ENSMUST00000077585.2
olfactory receptor 99
chr4_+_40920047 0.38 ENSMUST00000030122.4
serine peptidase inhibitor, Kazal type 4
chr15_+_89075996 0.38 ENSMUST00000081702.5
TraB domain containing
chr17_-_31144271 0.38 ENSMUST00000024826.7
trefoil factor 2 (spasmolytic protein 1)
chr6_+_125320633 0.38 ENSMUST00000176655.1
ENSMUST00000176110.1
sodium channel, nonvoltage-gated 1 alpha
chr17_-_23771543 0.38 ENSMUST00000086325.5
FLYWCH-type zinc finger 1
chr16_+_17276337 0.38 ENSMUST00000159065.1
ENSMUST00000159494.1
ENSMUST00000159811.1
transmembrane protein 191C
chr9_-_119339989 0.37 ENSMUST00000035092.6
myeloid differentiation primary response gene 88
chr15_+_100353149 0.37 ENSMUST00000075675.5
ENSMUST00000088142.5
ENSMUST00000176287.1
cDNA sequence AB099516
methyltransferase like 7A2
chr17_-_34031544 0.37 ENSMUST00000025186.8
solute carrier family 39 (zinc transporter), member 7
chr3_+_96181151 0.37 ENSMUST00000035371.8
synaptic vesicle glycoprotein 2 a
chr8_+_119437118 0.37 ENSMUST00000152420.1
ENSMUST00000098365.3
oxidative stress induced growth inhibitor 1
chr8_+_70302761 0.37 ENSMUST00000150968.1
coatomer protein complex, subunit epsilon
chr13_-_18382041 0.36 ENSMUST00000139064.2
ENSMUST00000175703.2
POU domain, class 6, transcription factor 2
chr18_+_31931470 0.36 ENSMUST00000025254.7
LIM and senescent cell antigen like domains 2
chr19_+_58728887 0.36 ENSMUST00000048644.5
pancreatic lipase related protein 1
chr14_-_57398483 0.36 ENSMUST00000022517.7
crystallin, lambda 1
chr17_+_25471564 0.36 ENSMUST00000025002.1
tektin 4
chr1_-_135167606 0.36 ENSMUST00000027682.8
G protein-coupled receptor 37-like 1
chr6_-_48445678 0.36 ENSMUST00000114556.1
zinc finger protein 467
chr17_+_35821675 0.36 ENSMUST00000003635.6
immediate early response 3
chr7_-_44816586 0.36 ENSMUST00000047356.8
activating transcription factor 5
chr7_+_12881165 0.36 ENSMUST00000144578.1
zinc finger protein 128
chr1_-_184883218 0.35 ENSMUST00000048308.5
RIKEN cDNA C130074G19 gene
chr5_+_114146525 0.35 ENSMUST00000102582.1
acetyl-Coenzyme A carboxylase beta
chr6_+_72097561 0.35 ENSMUST00000069994.4
ENSMUST00000114112.1
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
chr7_-_100656953 0.35 ENSMUST00000107046.1
ENSMUST00000107045.1
ENSMUST00000139708.1
pleckstrin homology domain containing, family B (evectins) member 1
chr15_+_84720052 0.35 ENSMUST00000006029.4
ENSMUST00000172307.2
Rho GTPase activating protein 8
chrX_-_155623325 0.35 ENSMUST00000038665.5
patched domain containing 1
chr8_-_105966038 0.35 ENSMUST00000116429.2
ENSMUST00000034370.9
solute carrier family 12, member 4
chr2_-_6213033 0.35 ENSMUST00000042658.2
enoyl Coenzyme A hydratase domain containing 3
chr7_-_30861470 0.34 ENSMUST00000052700.3
free fatty acid receptor 1
chr17_-_87282793 0.34 ENSMUST00000146560.2
RIKEN cDNA 4833418N02 gene
chr2_-_10130638 0.34 ENSMUST00000042290.7
inter-alpha trypsin inhibitor, heavy chain 2
chr17_-_26508463 0.34 ENSMUST00000025025.6
dual specificity phosphatase 1
chr19_+_42247544 0.34 ENSMUST00000122375.1
golgi autoantigen, golgin subfamily a, 7B
chr4_-_43653560 0.33 ENSMUST00000107870.2
sperm associated antigen 8
chr7_-_3720382 0.33 ENSMUST00000078451.6
paired Ig-like receptor B
chr10_-_24927444 0.33 ENSMUST00000020161.8
arginase, liver
chr4_+_134343181 0.33 ENSMUST00000105873.1
ENSMUST00000105874.2
solute carrier family 30 (zinc transporter), member 2
chr8_-_45975224 0.33 ENSMUST00000095323.1
ENSMUST00000098786.2
RIKEN cDNA 1700029J07 gene
chr16_+_49855618 0.32 ENSMUST00000084838.6
CD47 antigen (Rh-related antigen, integrin-associated signal transducer)
chr16_-_20426322 0.32 ENSMUST00000115547.2
ENSMUST00000096199.4
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
chr8_-_33641940 0.32 ENSMUST00000095349.4
UBX domain protein 8
chr1_-_87573825 0.32 ENSMUST00000068681.5
neuronal guanine nucleotide exchange factor
chr8_+_70724064 0.31 ENSMUST00000034307.7
ENSMUST00000110095.2
phosphodiesterase 4C, cAMP specific
chr4_-_156059414 0.31 ENSMUST00000184348.1
tubulin tyrosine ligase-like family, member 10
chr2_+_32288244 0.31 ENSMUST00000113377.1
ENSMUST00000100194.2
golgi autoantigen, golgin subfamily a, 2
chr15_-_82794236 0.31 ENSMUST00000006094.4
cytochrome P450, family 2, subfamily d, polypeptide 26
chr11_+_78536393 0.31 ENSMUST00000050366.8
ENSMUST00000108275.1
intraflagellar transport 20
chr4_-_96553617 0.31 ENSMUST00000030303.5
cytochrome P450, family 2, subfamily j, polypeptide 6
chr1_+_171503410 0.31 ENSMUST00000081527.1
Aly/REF export factor 2
chr18_-_22171392 0.31 ENSMUST00000025160.2
coiled coil domain containing 178
chr17_+_72836678 0.31 ENSMUST00000045174.5
yippee-like 5 (Drosophila)
chr3_-_130061553 0.30 ENSMUST00000168675.1
Sec24 related gene family, member B (S. cerevisiae)
chr12_+_10369967 0.30 ENSMUST00000118657.1
ENSMUST00000143739.1
ENSMUST00000002456.8
5'-nucleotidase, cytosolic IB
chr10_+_79997463 0.30 ENSMUST00000171637.1
ENSMUST00000043866.7
ATP-binding cassette, sub-family A (ABC1), member 7
chr5_-_31241215 0.30 ENSMUST00000068997.3
predicted gene 9970
chr7_-_45459839 0.30 ENSMUST00000094434.4
ferritin light chain 1
chr4_+_132974102 0.30 ENSMUST00000030693.6
Gardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog
chr10_-_125308809 0.30 ENSMUST00000105257.2
solute carrier family 16 (monocarboxylic acid transporters), member 7
chr3_+_118562129 0.30 ENSMUST00000039177.7
dihydropyrimidine dehydrogenase
chr4_-_148151646 0.30 ENSMUST00000132083.1
F-box protein 6
chr19_+_53529100 0.30 ENSMUST00000038287.6
dual specificity phosphatase 5
chr7_+_30699783 0.30 ENSMUST00000013227.7
RIKEN cDNA 2200002J24 gene
chr7_+_100178679 0.30 ENSMUST00000170954.2
ENSMUST00000049333.5
ENSMUST00000179842.1
potassium voltage-gated channel, Isk-related subfamily, gene 3
chr11_+_78536355 0.30 ENSMUST00000128788.1
intraflagellar transport 20
chr11_-_102447647 0.29 ENSMUST00000049057.4
family with sequence similarity 171, member A2
chr17_-_28486082 0.29 ENSMUST00000079413.3
FK506 binding protein 5
chr13_-_99900645 0.29 ENSMUST00000022150.6
CART prepropeptide
chr2_-_3422576 0.29 ENSMUST00000144584.1
meiosis expressed gene 1
chr5_+_130219706 0.29 ENSMUST00000065329.6
transmembrane protein 248
chr14_-_30626196 0.29 ENSMUST00000112210.3
ENSMUST00000112211.2
ENSMUST00000112208.1
protein kinase C, delta
chr5_+_137981512 0.29 ENSMUST00000035390.5
alpha-2-glycoprotein 1, zinc
chr15_+_89076058 0.28 ENSMUST00000169891.1
TraB domain containing
chr11_+_119307764 0.28 ENSMUST00000106250.1
caspase recruitment domain family, member 14
chr4_-_111902754 0.28 ENSMUST00000102719.1
ENSMUST00000102721.1
solute carrier family 5 (sodium/glucose cotransporter), member 9
chr12_-_78980758 0.28 ENSMUST00000174072.1
transmembrane protein 229B
chr16_+_23107413 0.28 ENSMUST00000023599.6
ENSMUST00000168891.1
eukaryotic translation initiation factor 4A2
chr2_+_131210363 0.28 ENSMUST00000110210.1
ENSMUST00000089506.5
ENSMUST00000110208.1
adaptor-related protein 5 complex, sigma 1 subunit
chr9_-_104063049 0.28 ENSMUST00000035166.5
ubiquitin-like modifier activating enzyme 5
chr4_+_137862237 0.28 ENSMUST00000102518.3
endothelin converting enzyme 1
chr2_+_164948219 0.28 ENSMUST00000017881.2
matrix metallopeptidase 9
chr4_+_134343466 0.28 ENSMUST00000105872.1
solute carrier family 30 (zinc transporter), member 2
chr11_+_116593687 0.28 ENSMUST00000153476.1
arylalkylamine N-acetyltransferase
chr2_+_131210501 0.27 ENSMUST00000110206.1
adaptor-related protein 5 complex, sigma 1 subunit
chr9_+_48495345 0.27 ENSMUST00000048824.7
predicted gene 5617
chr7_+_144915100 0.27 ENSMUST00000128057.1
oral cancer overexpressed 1
chr19_-_24477356 0.27 ENSMUST00000099556.1
family with sequence similarity 122, member A
chr1_-_191062896 0.27 ENSMUST00000085633.5
ENSMUST00000110891.1
ENSMUST00000027945.5
ENSMUST00000110893.3
TatD DNase domain containing 3
chr5_-_116024475 0.27 ENSMUST00000111999.1
protein kinase, AMP-activated, beta 1 non-catalytic subunit
chr13_-_41487306 0.27 ENSMUST00000021794.6
neural precursor cell expressed, developmentally down-regulated gene 9
chr4_+_141793612 0.27 ENSMUST00000097805.4
ENSMUST00000030747.4
ENSMUST00000153094.1
caspase 9
chr8_-_35826435 0.27 ENSMUST00000060128.5
claudin 23
chr7_+_16843049 0.27 ENSMUST00000086104.4
protein kinase D2
chr1_-_37865040 0.27 ENSMUST00000041815.8
testis specific 10
chr19_+_42255704 0.26 ENSMUST00000087123.5
golgi autoantigen, golgin subfamily a, 7B
chr12_+_109549157 0.26 ENSMUST00000128458.1
ENSMUST00000150851.1
maternally expressed 3
chr11_-_69060483 0.26 ENSMUST00000101007.2
RIKEN cDNA 9330160F10 gene
chr11_+_103103051 0.26 ENSMUST00000152971.1
acyl-Coenzyme A binding domain containing 4
chr7_-_45136391 0.26 ENSMUST00000146760.1
FMS-like tyrosine kinase 3 ligand
chr11_+_74830920 0.26 ENSMUST00000000291.2
max binding protein
chr12_+_109747903 0.26 ENSMUST00000183084.1
ENSMUST00000182300.1
miRNA containing gene
chr7_+_28440927 0.26 ENSMUST00000078845.6
glia maturation factor, gamma
chr4_+_134102581 0.26 ENSMUST00000074690.4
ENSMUST00000070246.2
ENSMUST00000156750.1
UBX domain protein 11
chr11_+_73177083 0.26 ENSMUST00000040687.5
Tax1 (human T cell leukemia virus type I) binding protein 3
chr18_+_74065102 0.26 ENSMUST00000066583.1
predicted gene 9925
chr9_+_74861888 0.26 ENSMUST00000056006.9
one cut domain, family member 1
chr14_-_30607808 0.26 ENSMUST00000112207.1
ENSMUST00000112206.1
ENSMUST00000112202.1
ENSMUST00000112203.1
protein kinase C, delta
chr2_-_13793793 0.26 ENSMUST00000003509.8
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 6
chr6_+_125552948 0.26 ENSMUST00000112254.1
ENSMUST00000112253.1
ENSMUST00000001995.7
Von Willebrand factor homolog
chr7_+_99535652 0.26 ENSMUST00000032995.8
ENSMUST00000162404.1
arrestin, beta 1
chr11_+_117308135 0.25 ENSMUST00000153668.1
septin 9
chr7_-_3845050 0.25 ENSMUST00000108615.3
ENSMUST00000119469.1
paired-Ig-like receptor A2
chr4_-_156050465 0.25 ENSMUST00000184684.1
tubulin tyrosine ligase-like family, member 10
chr3_+_102469918 0.25 ENSMUST00000106925.2
ENSMUST00000035952.3
nerve growth factor
chr15_-_78803015 0.25 ENSMUST00000164826.1
caspase recruitment domain family, member 10
chr12_+_35992900 0.25 ENSMUST00000020898.5
anterior gradient 2
chr12_-_69790660 0.25 ENSMUST00000021377.4
cyclin-dependent kinase-like 1 (CDC2-related kinase)
chr1_+_88134786 0.25 ENSMUST00000113134.1
ENSMUST00000140092.1
UDP glucuronosyltransferase 1 family, polypeptide A6A
chr2_-_66568312 0.25 ENSMUST00000112354.1
sodium channel, voltage-gated, type IX, alpha
chr8_+_4226827 0.24 ENSMUST00000053035.6
leucine rich repeat containing 8 family, member E
chr5_-_136883115 0.24 ENSMUST00000057497.6
ENSMUST00000111103.1
collagen, type XXVI, alpha 1
chr2_+_32288317 0.24 ENSMUST00000131712.1
ENSMUST00000133113.1
ENSMUST00000081670.6
ENSMUST00000147707.1
ENSMUST00000129193.1
golgi autoantigen, golgin subfamily a, 2
chr2_+_91202885 0.24 ENSMUST00000150403.1
ENSMUST00000002172.7
ENSMUST00000155418.1
acid phosphatase 2, lysosomal
chr3_+_27182965 0.24 ENSMUST00000046515.8
neutral cholesterol ester hydrolase 1
chr8_+_45975514 0.24 ENSMUST00000034051.6
UFM1-specific peptidase 2
chr8_-_22476809 0.24 ENSMUST00000163774.1
ENSMUST00000033935.8
small integral membrane protein 19
chr7_+_28441026 0.24 ENSMUST00000135686.1
glia maturation factor, gamma

Network of associatons between targets according to the STRING database.

First level regulatory network of Esr1

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.5 GO:0033869 coenzyme A catabolic process(GO:0015938) nucleoside bisphosphate catabolic process(GO:0033869) ribonucleoside bisphosphate catabolic process(GO:0034031) purine nucleoside bisphosphate catabolic process(GO:0034034) acetyl-CoA catabolic process(GO:0046356)
0.3 1.7 GO:0002835 negative regulation of response to tumor cell(GO:0002835) negative regulation of immune response to tumor cell(GO:0002838)
0.3 0.8 GO:0061090 positive regulation of sequestering of zinc ion(GO:0061090)
0.2 0.8 GO:0002767 immune response-inhibiting cell surface receptor signaling pathway(GO:0002767)
0.2 1.1 GO:0032439 endosome localization(GO:0032439)
0.2 0.4 GO:2001293 malonyl-CoA metabolic process(GO:2001293)
0.2 0.7 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.2 0.5 GO:0071846 actin filament debranching(GO:0071846)
0.2 0.5 GO:0006216 cytidine catabolic process(GO:0006216) cytidine deamination(GO:0009972) cytidine metabolic process(GO:0046087)
0.2 0.5 GO:1900620 acetylcholine biosynthetic process(GO:0008292) acetate ester biosynthetic process(GO:1900620)
0.2 0.6 GO:1900533 medium-chain fatty-acyl-CoA catabolic process(GO:0036114) fatty-acyl-CoA catabolic process(GO:0036115) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
0.1 0.4 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241)
0.1 0.6 GO:0072566 chemokine (C-X-C motif) ligand 1 production(GO:0072566) regulation of chemokine (C-X-C motif) ligand 1 production(GO:2000338)
0.1 0.7 GO:0033277 abortive mitotic cell cycle(GO:0033277)
0.1 0.6 GO:0060697 positive regulation of phospholipid catabolic process(GO:0060697)
0.1 0.6 GO:0019244 lactate biosynthetic process from pyruvate(GO:0019244)
0.1 0.5 GO:0080154 regulation of fertilization(GO:0080154)
0.1 0.1 GO:0035995 detection of muscle stretch(GO:0035995)
0.1 0.4 GO:0071449 cellular response to lipid hydroperoxide(GO:0071449)
0.1 0.3 GO:0019859 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859) thymidine metabolic process(GO:0046104)
0.1 0.3 GO:1901074 regulation of engulfment of apoptotic cell(GO:1901074)
0.1 0.3 GO:0070093 negative regulation of glucagon secretion(GO:0070093)
0.1 0.6 GO:0038161 prolactin signaling pathway(GO:0038161)
0.1 0.6 GO:0018094 protein polyglycylation(GO:0018094)
0.1 0.3 GO:0034959 substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.1 0.2 GO:2000563 positive regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000563)
0.1 0.2 GO:2000850 negative regulation of corticosteroid hormone secretion(GO:2000847) negative regulation of glucocorticoid secretion(GO:2000850)
0.1 0.4 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.1 0.8 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.1 0.4 GO:0000103 sulfate assimilation(GO:0000103)
0.1 0.2 GO:1903371 regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.1 0.7 GO:1901727 positive regulation of histone deacetylase activity(GO:1901727)
0.1 0.3 GO:0044778 meiotic DNA integrity checkpoint(GO:0044778)
0.1 0.3 GO:0090467 L-arginine import(GO:0043091) arginine import(GO:0090467)
0.1 0.4 GO:0070459 prolactin secretion(GO:0070459)
0.1 0.6 GO:0090306 spindle assembly involved in meiosis(GO:0090306)
0.1 0.3 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.1 0.2 GO:0035585 calcium-mediated signaling using extracellular calcium source(GO:0035585)
0.1 0.3 GO:1901475 pyruvate transmembrane transport(GO:1901475)
0.1 0.3 GO:1902303 negative regulation of potassium ion export(GO:1902303)
0.1 0.2 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
0.1 0.4 GO:0060455 negative regulation of gastric acid secretion(GO:0060455)
0.1 0.2 GO:1903896 positive regulation of IRE1-mediated unfolded protein response(GO:1903896)
0.1 0.3 GO:0035359 negative regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035359)
0.1 0.5 GO:1900122 positive regulation of receptor binding(GO:1900122)
0.1 0.3 GO:0009597 detection of virus(GO:0009597)
0.1 0.4 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.1 0.7 GO:0052697 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.1 0.2 GO:0048807 female genitalia morphogenesis(GO:0048807)
0.1 0.2 GO:1990743 protein sialylation(GO:1990743)
0.1 0.5 GO:0014052 regulation of gamma-aminobutyric acid secretion(GO:0014052)
0.1 0.4 GO:1903142 positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.1 0.3 GO:0014063 negative regulation of serotonin secretion(GO:0014063)
0.1 0.6 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.1 0.5 GO:0035878 nail development(GO:0035878)
0.1 0.2 GO:0006566 threonine metabolic process(GO:0006566)
0.1 0.2 GO:0090481 pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.1 0.6 GO:0030432 peristalsis(GO:0030432)
0.1 0.3 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.1 0.4 GO:2000346 negative regulation of hepatocyte proliferation(GO:2000346)
0.1 0.4 GO:1901029 negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
0.1 0.2 GO:1901052 sarcosine metabolic process(GO:1901052) sarcosine catabolic process(GO:1901053)
0.0 0.2 GO:0070295 renal water absorption(GO:0070295)
0.0 0.1 GO:0000715 nucleotide-excision repair, DNA damage recognition(GO:0000715)
0.0 0.2 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.0 0.4 GO:0008228 opsonization(GO:0008228)
0.0 0.6 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.0 0.3 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0 0.2 GO:0010360 negative regulation of anion channel activity(GO:0010360)
0.0 0.2 GO:0038165 oncostatin-M-mediated signaling pathway(GO:0038165)
0.0 0.9 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.0 0.1 GO:1903632 positive regulation of aminoacyl-tRNA ligase activity(GO:1903632)
0.0 0.1 GO:0007356 thorax and anterior abdomen determination(GO:0007356) negative regulation of metanephric glomerulus development(GO:0072299) negative regulation of metanephric glomerular mesangial cell proliferation(GO:0072302) regulation of metanephric ureteric bud development(GO:2001074) positive regulation of metanephric ureteric bud development(GO:2001076)
0.0 0.2 GO:0034769 basement membrane disassembly(GO:0034769)
0.0 0.1 GO:0098976 excitatory chemical synaptic transmission(GO:0098976) positive regulation of AMPA glutamate receptor clustering(GO:1904719)
0.0 0.4 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.0 0.1 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.0 0.3 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.0 0.2 GO:0031587 positive regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0031587) positive regulation of neurotrophin production(GO:0032901)
0.0 0.1 GO:0015755 fructose transport(GO:0015755)
0.0 0.2 GO:0016115 terpenoid catabolic process(GO:0016115)
0.0 0.3 GO:0014042 positive regulation of neuron maturation(GO:0014042)
0.0 0.2 GO:0060598 dichotomous subdivision of terminal units involved in mammary gland duct morphogenesis(GO:0060598)
0.0 0.1 GO:0045415 negative regulation of interleukin-8 biosynthetic process(GO:0045415)
0.0 0.1 GO:0048611 ectodermal digestive tract development(GO:0007439) embryonic ectodermal digestive tract development(GO:0048611)
0.0 0.5 GO:1903818 positive regulation of voltage-gated potassium channel activity(GO:1903818)
0.0 0.3 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0 0.2 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.0 0.1 GO:0006780 uroporphyrinogen III biosynthetic process(GO:0006780)
0.0 0.2 GO:0044375 regulation of peroxisome size(GO:0044375)
0.0 0.9 GO:0050907 detection of chemical stimulus involved in sensory perception(GO:0050907)
0.0 0.6 GO:0035814 negative regulation of renal sodium excretion(GO:0035814)
0.0 0.1 GO:1903575 cornified envelope assembly(GO:1903575)
0.0 0.2 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.0 0.4 GO:2000009 negative regulation of protein localization to cell surface(GO:2000009)
0.0 0.2 GO:0097411 hypoxia-inducible factor-1alpha signaling pathway(GO:0097411)
0.0 0.9 GO:0050909 sensory perception of taste(GO:0050909)
0.0 0.1 GO:1904566 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.0 0.1 GO:0071718 sodium-independent icosanoid transport(GO:0071718)
0.0 0.1 GO:1900149 positive regulation of Schwann cell migration(GO:1900149)
0.0 0.2 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0 0.2 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.0 0.3 GO:0061002 negative regulation of dendritic spine morphogenesis(GO:0061002)
0.0 0.3 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.7 GO:0048712 negative regulation of astrocyte differentiation(GO:0048712)
0.0 0.2 GO:0002024 diet induced thermogenesis(GO:0002024)
0.0 0.1 GO:2000321 positive regulation of T-helper 17 cell differentiation(GO:2000321)
0.0 0.1 GO:0060785 regulation of apoptosis involved in tissue homeostasis(GO:0060785)
0.0 0.1 GO:0003127 detection of nodal flow(GO:0003127) detection of endogenous stimulus(GO:0009726)
0.0 0.6 GO:0061436 establishment of skin barrier(GO:0061436)
0.0 0.1 GO:0099526 presynaptic signal transduction(GO:0098928) presynapse to nucleus signaling pathway(GO:0099526)
0.0 0.3 GO:2000671 regulation of motor neuron apoptotic process(GO:2000671)
0.0 0.1 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.0 0.2 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.0 0.6 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 0.2 GO:0071294 cellular response to zinc ion(GO:0071294)
0.0 0.2 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.0 0.2 GO:0048102 autophagic cell death(GO:0048102)
0.0 0.1 GO:0035106 operant conditioning(GO:0035106)
0.0 0.4 GO:0098719 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 1.3 GO:0097009 energy homeostasis(GO:0097009)
0.0 0.2 GO:0015747 urate transport(GO:0015747)
0.0 0.2 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.0 0.1 GO:0032916 evasion or tolerance of host defenses by virus(GO:0019049) positive regulation of transforming growth factor beta3 production(GO:0032916) avoidance of host defenses(GO:0044413) evasion or tolerance of host defenses(GO:0044415) avoidance of defenses of other organism involved in symbiotic interaction(GO:0051832) evasion or tolerance of defenses of other organism involved in symbiotic interaction(GO:0051834)
0.0 0.2 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.0 0.1 GO:0090649 response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.0 0.4 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.3 GO:0042435 indole-containing compound biosynthetic process(GO:0042435)
0.0 0.5 GO:0007289 spermatid nucleus differentiation(GO:0007289)
0.0 0.1 GO:0006742 NADP catabolic process(GO:0006742)
0.0 0.1 GO:0015801 aromatic amino acid transport(GO:0015801) tryptophan transport(GO:0015827)
0.0 0.2 GO:0071318 cellular response to ATP(GO:0071318)
0.0 0.0 GO:0006532 aspartate biosynthetic process(GO:0006532)
0.0 0.1 GO:0038163 endomitotic cell cycle(GO:0007113) thrombopoietin-mediated signaling pathway(GO:0038163) positive regulation of male germ cell proliferation(GO:2000256)
0.0 0.3 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.1 GO:1901252 regulation of intracellular transport of viral material(GO:1901252)
0.0 0.2 GO:0046959 habituation(GO:0046959)
0.0 0.1 GO:0021660 rhombomere formation(GO:0021594) rhombomere 3 formation(GO:0021660) rhombomere 5 morphogenesis(GO:0021664) rhombomere 5 formation(GO:0021666)
0.0 0.2 GO:0051533 positive regulation of NFAT protein import into nucleus(GO:0051533)
0.0 0.1 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.0 0.1 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.0 0.5 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 0.2 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
0.0 0.1 GO:0001923 B-1 B cell differentiation(GO:0001923)
0.0 0.1 GO:0090370 negative regulation of cholesterol efflux(GO:0090370)
0.0 0.0 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.0 0.0 GO:0060167 regulation of adenosine receptor signaling pathway(GO:0060167) positive regulation of adenosine receptor signaling pathway(GO:0060168)
0.0 0.3 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.2 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.0 0.1 GO:0003134 BMP signaling pathway involved in heart induction(GO:0003130) endodermal-mesodermal cell signaling(GO:0003133) endodermal-mesodermal cell signaling involved in heart induction(GO:0003134)
0.0 0.2 GO:0090141 positive regulation of mitochondrial fission(GO:0090141)
0.0 0.1 GO:0072086 specification of loop of Henle identity(GO:0072086)
0.0 0.2 GO:0097646 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.0 0.4 GO:0033008 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.0 0.2 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.1 GO:0002175 protein localization to paranode region of axon(GO:0002175)
0.0 0.1 GO:0019695 choline metabolic process(GO:0019695)
0.0 0.1 GO:0060060 post-embryonic retina morphogenesis in camera-type eye(GO:0060060)
0.0 0.1 GO:0090024 negative regulation of granulocyte chemotaxis(GO:0071623) negative regulation of neutrophil chemotaxis(GO:0090024)
0.0 0.1 GO:0043181 vacuolar sequestering(GO:0043181)
0.0 0.1 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.0 GO:0036135 Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)
0.0 0.3 GO:0021794 thalamus development(GO:0021794)
0.0 0.1 GO:0023016 signal transduction by trans-phosphorylation(GO:0023016)
0.0 0.0 GO:0006713 glucocorticoid catabolic process(GO:0006713)
0.0 0.1 GO:0072282 metanephric nephron tubule morphogenesis(GO:0072282)
0.0 0.6 GO:0006904 vesicle docking involved in exocytosis(GO:0006904)
0.0 0.3 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.1 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
0.0 0.1 GO:0035999 tetrahydrofolate interconversion(GO:0035999)
0.0 0.1 GO:0030916 otic vesicle formation(GO:0030916)
0.0 0.1 GO:0001955 blood vessel maturation(GO:0001955)
0.0 0.3 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.3 GO:0071549 cellular response to dexamethasone stimulus(GO:0071549)
0.0 0.1 GO:0000098 sulfur amino acid catabolic process(GO:0000098)
0.0 0.0 GO:0046122 deoxyribonucleoside catabolic process(GO:0046121) purine deoxyribonucleoside metabolic process(GO:0046122)
0.0 0.1 GO:0086073 bundle of His cell-Purkinje myocyte adhesion involved in cell communication(GO:0086073)
0.0 0.1 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
0.0 0.3 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.1 GO:0030423 targeting of mRNA for destruction involved in RNA interference(GO:0030423)
0.0 0.6 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.1 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.0 0.2 GO:0060314 regulation of ryanodine-sensitive calcium-release channel activity(GO:0060314)
0.0 0.1 GO:0042997 negative regulation of Golgi to plasma membrane protein transport(GO:0042997) negative regulation of establishment of protein localization to plasma membrane(GO:0090005)
0.0 0.1 GO:0032290 peripheral nervous system myelin formation(GO:0032290)
0.0 0.3 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0 0.1 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.0 0.1 GO:1904715 negative regulation of chaperone-mediated autophagy(GO:1904715)
0.0 0.1 GO:1904659 glucose transmembrane transport(GO:1904659)
0.0 0.1 GO:0015817 histidine transport(GO:0015817)
0.0 0.1 GO:1905146 lysosomal protein catabolic process(GO:1905146)
0.0 0.1 GO:0006538 glutamate catabolic process(GO:0006538)
0.0 0.3 GO:0008340 determination of adult lifespan(GO:0008340)
0.0 0.3 GO:0019369 arachidonic acid metabolic process(GO:0019369)
0.0 0.1 GO:0045779 negative regulation of bone resorption(GO:0045779)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:1902636 kinociliary basal body(GO:1902636)
0.1 0.4 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.1 1.1 GO:0045179 apical cortex(GO:0045179)
0.1 0.7 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.1 0.3 GO:0043293 apoptosome(GO:0043293)
0.1 0.2 GO:0034666 integrin alpha2-beta1 complex(GO:0034666)
0.1 0.2 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.1 0.2 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.1 0.1 GO:0044753 amphisome(GO:0044753)
0.1 0.7 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.1 0.5 GO:0033093 Weibel-Palade body(GO:0033093)
0.1 0.9 GO:0035686 sperm fibrous sheath(GO:0035686)
0.1 0.6 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 1.1 GO:0031528 microvillus membrane(GO:0031528)
0.0 0.4 GO:0031983 vesicle lumen(GO:0031983)
0.0 0.3 GO:0030896 checkpoint clamp complex(GO:0030896)
0.0 0.6 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.0 0.1 GO:0030905 retromer, tubulation complex(GO:0030905)
0.0 0.1 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.0 0.1 GO:0098855 HCN channel complex(GO:0098855)
0.0 0.1 GO:0071942 XPC complex(GO:0071942)
0.0 0.1 GO:0031417 NatC complex(GO:0031417)
0.0 0.1 GO:0072534 perineuronal net(GO:0072534)
0.0 0.2 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.0 0.3 GO:0044754 autolysosome(GO:0044754)
0.0 0.3 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.3 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.1 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.0 0.4 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.6 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.2 GO:1903439 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.0 0.2 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.1 GO:0097454 Schwann cell microvillus(GO:0097454)
0.0 0.5 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.1 GO:1990745 EARP complex(GO:1990745)
0.0 0.3 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.4 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.3 GO:0031105 septin complex(GO:0031105)
0.0 0.4 GO:0000145 exocyst(GO:0000145)
0.0 0.4 GO:0034706 sodium channel complex(GO:0034706)
0.0 0.1 GO:0072559 NLRP3 inflammasome complex(GO:0072559)
0.0 0.1 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.0 0.4 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.1 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.5 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.0 0.1 GO:0071144 SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.2 GO:0044294 dendritic growth cone(GO:0044294)
0.0 0.2 GO:0000812 Swr1 complex(GO:0000812)
0.0 0.2 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.1 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.0 0.1 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 0.2 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.0 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.0 0.3 GO:0042611 MHC protein complex(GO:0042611)
0.0 0.5 GO:0030119 AP-type membrane coat adaptor complex(GO:0030119)
0.0 2.5 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 0.1 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.4 GO:0005865 striated muscle thin filament(GO:0005865)
0.0 0.2 GO:0031143 pseudopodium(GO:0031143)
0.0 0.2 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.3 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0070996 type 1 melanocortin receptor binding(GO:0070996)
0.3 1.5 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.2 0.9 GO:0070976 TIR domain binding(GO:0070976)
0.2 0.9 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.2 0.6 GO:0070737 protein-glycine ligase activity, elongating(GO:0070737)
0.2 0.7 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.2 0.6 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.1 0.4 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.1 0.6 GO:0004994 somatostatin receptor activity(GO:0004994)
0.1 0.6 GO:0004925 prolactin receptor activity(GO:0004925)
0.1 0.3 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.1 0.4 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.1 0.3 GO:0034188 apolipoprotein receptor activity(GO:0030226) apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.1 0.6 GO:0002046 opsin binding(GO:0002046)
0.1 0.3 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.1 0.3 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
0.1 0.7 GO:0019198 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1 0.5 GO:0004126 cytidine deaminase activity(GO:0004126)
0.1 0.4 GO:0070012 oligopeptidase activity(GO:0070012)
0.1 0.2 GO:0004923 leukemia inhibitory factor receptor activity(GO:0004923)
0.1 0.3 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.1 0.2 GO:0019002 GMP binding(GO:0019002)
0.1 0.2 GO:0004771 sterol esterase activity(GO:0004771)
0.1 0.2 GO:0004793 threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.1 0.4 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.1 0.3 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.1 0.2 GO:0015275 stretch-activated, cation-selective, calcium channel activity(GO:0015275)
0.1 0.5 GO:0033265 choline transmembrane transporter activity(GO:0015220) choline binding(GO:0033265)
0.1 0.6 GO:0046790 virion binding(GO:0046790)
0.1 0.2 GO:0005128 erythropoietin receptor binding(GO:0005128)
0.1 0.6 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.1 0.1 GO:0030549 acetylcholine receptor activator activity(GO:0030549)
0.1 0.4 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.1 0.3 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.1 0.2 GO:0004985 opioid receptor activity(GO:0004985)
0.1 0.2 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.1 0.2 GO:0004977 melanocortin receptor activity(GO:0004977)
0.1 0.2 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.1 0.3 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.1 0.2 GO:0008480 sarcosine dehydrogenase activity(GO:0008480) oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997)
0.1 0.3 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.5 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.3 GO:0002054 nucleobase binding(GO:0002054)
0.0 0.2 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0 0.1 GO:0004698 calcium-dependent protein kinase C activity(GO:0004698)
0.0 0.2 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656) procollagen-proline dioxygenase activity(GO:0019798)
0.0 1.4 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.6 GO:0036042 long-chain fatty acyl-CoA binding(GO:0036042)
0.0 0.3 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.4 GO:1990239 steroid hormone binding(GO:1990239)
0.0 0.7 GO:0070330 aromatase activity(GO:0070330)
0.0 0.2 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.3 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.7 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.1 GO:0001132 RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly(GO:0001129) RNA polymerase II transcription factor activity, TBP-class protein binding(GO:0001132)
0.0 0.4 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.2 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.0 0.5 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 1.3 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.6 GO:0070403 NAD+ binding(GO:0070403)
0.0 0.5 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.0 0.4 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.2 GO:0031849 olfactory receptor binding(GO:0031849)
0.0 0.1 GO:1990460 leptin receptor binding(GO:1990460)
0.0 0.1 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.7 GO:0045125 bioactive lipid receptor activity(GO:0045125)
0.0 0.2 GO:0015288 porin activity(GO:0015288)
0.0 0.3 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 0.3 GO:0009881 photoreceptor activity(GO:0009881)
0.0 0.4 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.2 GO:0048039 ubiquinone binding(GO:0048039)
0.0 0.2 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.1 GO:0072541 peroxynitrite reductase activity(GO:0072541)
0.0 0.3 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.2 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.0 0.1 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.0 0.2 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.0 0.2 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.2 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0 0.4 GO:0016918 retinal binding(GO:0016918) retinol binding(GO:0019841)
0.0 0.3 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.2 GO:0003993 acid phosphatase activity(GO:0003993)
0.0 0.5 GO:0051400 BH domain binding(GO:0051400)
0.0 0.2 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.0 0.2 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.1 GO:0016880 acid-ammonia (or amide) ligase activity(GO:0016880)
0.0 0.2 GO:0097643 amylin receptor activity(GO:0097643)
0.0 0.3 GO:0019865 immunoglobulin binding(GO:0019865)
0.0 0.3 GO:0042301 phosphate ion binding(GO:0042301)
0.0 0.1 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.0 0.4 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.0 GO:0031711 bradykinin receptor binding(GO:0031711)
0.0 0.2 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 0.2 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
0.0 0.1 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.0 0.1 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.0 0.3 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.1 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.3 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.2 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.0 0.6 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.1 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.0 0.7 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.1 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.0 0.3 GO:0008641 small protein activating enzyme activity(GO:0008641)
0.0 0.1 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.0 0.1 GO:0015173 aromatic amino acid transmembrane transporter activity(GO:0015173)
0.0 0.1 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.0 0.5 GO:0043295 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.0 0.6 GO:0005272 sodium channel activity(GO:0005272)
0.0 0.1 GO:0001729 ceramide kinase activity(GO:0001729)
0.0 0.3 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.4 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.3 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.1 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.2 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.1 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0 0.1 GO:0008525 phosphatidylcholine transporter activity(GO:0008525)
0.0 0.7 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.0 0.2 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.3 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.2 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
0.0 0.1 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 0.2 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.0 GO:0047522 13-prostaglandin reductase activity(GO:0036132) 15-oxoprostaglandin 13-oxidase activity(GO:0047522)
0.0 0.1 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.0 0.1 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.0 0.3 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.1 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.0 0.1 GO:0001847 opsonin receptor activity(GO:0001847)
0.0 0.1 GO:0015254 glycerol channel activity(GO:0015254)
0.0 0.2 GO:0008417 fucosyltransferase activity(GO:0008417)
0.0 0.1 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.0 0.3 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.1 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.0 GO:0016501 prostacyclin receptor activity(GO:0016501)
0.0 0.1 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.0 0.1 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 2.1 GO:0008236 serine-type peptidase activity(GO:0008236) serine hydrolase activity(GO:0017171)
0.0 0.1 GO:0005290 L-histidine transmembrane transporter activity(GO:0005290)
0.0 0.1 GO:0004630 phospholipase D activity(GO:0004630)
0.0 0.1 GO:0030267 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.0 0.1 GO:0030547 receptor inhibitor activity(GO:0030547)
0.0 0.1 GO:0046972 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.0 0.3 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 0.0 GO:0050252 retinol O-fatty-acyltransferase activity(GO:0050252)
0.0 0.1 GO:0000268 peroxisome targeting sequence binding(GO:0000268)
0.0 0.2 GO:0015923 mannosidase activity(GO:0015923)
0.0 0.5 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.0 GO:0031687 A2A adenosine receptor binding(GO:0031687)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.6 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 1.2 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 1.5 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.3 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 0.2 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 0.3 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.4 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.4 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.6 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 0.7 PID ERBB1 RECEPTOR PROXIMAL PATHWAY EGF receptor (ErbB1) signaling pathway
0.0 0.4 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.3 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.1 1.4 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.1 0.9 REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES Genes involved in p75NTR recruits signalling complexes
0.1 0.7 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.1 0.8 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.4 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.4 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 0.7 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.5 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0 0.5 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.4 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.5 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.6 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.4 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.7 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 0.7 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 0.3 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.2 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.3 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 0.3 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.1 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.4 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 0.5 REACTOME SHC1 EVENTS IN EGFR SIGNALING Genes involved in SHC1 events in EGFR signaling
0.0 1.4 REACTOME AQUAPORIN MEDIATED TRANSPORT Genes involved in Aquaporin-mediated transport
0.0 0.3 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.2 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.1 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.0 0.3 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.3 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.3 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.3 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.3 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 0.2 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.6 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.3 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.4 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.1 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.3 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.2 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0 0.3 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.3 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA