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2D miR_HR1_12

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Results for Xbp1_Creb3l1

Z-value: 2.97

Motif logo

Transcription factors associated with Xbp1_Creb3l1

Gene Symbol Gene ID Gene Info
ENSMUSG00000020484.12 X-box binding protein 1
ENSMUSG00000027230.9 cAMP responsive element binding protein 3-like 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Creb3l1mm10_v2_chr2_-_92024502_920245290.922.6e-05Click!
Xbp1mm10_v2_chr11_+_5520652_55206590.881.8e-04Click!

Activity profile of Xbp1_Creb3l1 motif

Sorted Z-values of Xbp1_Creb3l1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr7_-_45092130 13.91 ENSMUST00000148175.1
reticulocalbin 3, EF-hand calcium binding domain
chr7_-_45092198 13.30 ENSMUST00000140449.1
ENSMUST00000117546.1
ENSMUST00000019683.3
reticulocalbin 3, EF-hand calcium binding domain
chr7_-_45091713 8.72 ENSMUST00000141576.1
reticulocalbin 3, EF-hand calcium binding domain
chr15_+_79516396 6.00 ENSMUST00000010974.7
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 3
chr3_+_93520473 5.25 ENSMUST00000029515.4
S100 calcium binding protein A11 (calgizzarin)
chr2_+_180725263 5.03 ENSMUST00000094218.3
solute carrier family 17, member 9
chr18_+_57354733 4.97 ENSMUST00000025490.8
proline-rich coiled-coil 1
chr15_-_32244632 4.52 ENSMUST00000181536.1
RIKEN cDNA 0610007N19
chr9_+_72925622 3.77 ENSMUST00000038489.5
pygopus 1
chr19_+_11965817 3.71 ENSMUST00000025590.9
oxysterol binding protein
chr5_+_113735782 3.61 ENSMUST00000065698.5
FIC domain containing
chr5_+_137288273 3.27 ENSMUST00000024099.4
ENSMUST00000085934.3
acetylcholinesterase
chr7_+_35555367 3.26 ENSMUST00000181932.1
RIKEN cDNA B230322F03 gene
chr6_-_54593139 3.21 ENSMUST00000046520.6
FK506 binding protein 14
chr5_+_92137896 3.07 ENSMUST00000031355.6
USO1 vesicle docking factor
chr10_-_128400448 3.03 ENSMUST00000167859.1
solute carrier family 39 (metal ion transporter), member 5
chr19_+_8741669 3.01 ENSMUST00000176314.1
ENSMUST00000073430.7
ENSMUST00000175901.1
syntaxin 5A
chr10_+_91082940 2.85 ENSMUST00000020150.3
IKBKB interacting protein
chr19_+_8741473 2.81 ENSMUST00000177373.1
ENSMUST00000010254.9
syntaxin 5A
chr4_-_118544010 2.78 ENSMUST00000128098.1
transmembrane protein 125
chr3_-_27710413 2.71 ENSMUST00000046157.4
fibronectin type III domain containing 3B
chr8_+_70302518 2.41 ENSMUST00000066469.7
coatomer protein complex, subunit epsilon
chr19_+_8741413 2.38 ENSMUST00000176381.1
syntaxin 5A
chr11_+_69095217 2.13 ENSMUST00000101004.2
period circadian clock 1
chr4_+_43562672 2.07 ENSMUST00000167751.1
ENSMUST00000132631.1
cAMP responsive element binding protein 3
chr2_-_168742100 2.05 ENSMUST00000109177.1
ATPase, class II, type 9A
chr6_-_126740151 2.05 ENSMUST00000112242.1
potassium voltage-gated channel, shaker-related, subfamily, member 6
chr9_-_104063049 2.01 ENSMUST00000035166.5
ubiquitin-like modifier activating enzyme 5
chr2_+_150786735 2.00 ENSMUST00000045441.7
brain glycogen phosphorylase
chr8_+_70302761 1.99 ENSMUST00000150968.1
coatomer protein complex, subunit epsilon
chr10_+_91083036 1.95 ENSMUST00000020149.5
IKBKB interacting protein
chr4_-_129640691 1.92 ENSMUST00000084264.5
taxilin alpha
chr4_-_114908892 1.87 ENSMUST00000068654.3
forkhead box D2
chrX_+_73787002 1.87 ENSMUST00000166518.1
signal sequence receptor, delta
chr6_+_70844499 1.86 ENSMUST00000034093.8
ENSMUST00000162950.1
eukaryotic translation initiation factor 2 alpha kinase 3
chr4_-_155653184 1.86 ENSMUST00000030937.1
matrix metallopeptidase 23
chr17_-_34031684 1.84 ENSMUST00000169397.1
solute carrier family 39 (zinc transporter), member 7
chr12_+_51377560 1.81 ENSMUST00000021335.5
Sec1 family domain containing 1
chr17_-_34031544 1.80 ENSMUST00000025186.8
solute carrier family 39 (zinc transporter), member 7
chr13_-_37994111 1.79 ENSMUST00000021864.6
signal sequence receptor, alpha
chr6_-_52204415 1.77 ENSMUST00000048794.6
homeobox A5
chr10_+_61680302 1.76 ENSMUST00000020285.8
SAR1 gene homolog A (S. cerevisiae)
chr5_+_64970069 1.75 ENSMUST00000031080.8
family with sequence similarity 114, member A1
chrX_+_73787062 1.73 ENSMUST00000002090.2
signal sequence receptor, delta
chr15_-_57892358 1.68 ENSMUST00000022993.5
Der1-like domain family, member 1
chr17_-_34031644 1.66 ENSMUST00000171872.1
solute carrier family 39 (zinc transporter), member 7
chr11_-_108343917 1.66 ENSMUST00000059595.4
protein kinase C, alpha
chr16_-_36874806 1.63 ENSMUST00000075946.5
ELL associated factor 2
chr18_+_51117754 1.62 ENSMUST00000116639.2
proline rich 16
chr5_+_143403819 1.61 ENSMUST00000110731.2
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2
chr14_+_20674311 1.61 ENSMUST00000048657.8
Sec24 related gene family, member C (S. cerevisiae)
chr16_+_36875119 1.60 ENSMUST00000135406.1
ENSMUST00000114812.1
ENSMUST00000134616.1
ENSMUST00000023534.6
golgi autoantigen, golgin subfamily b, macrogolgin 1
golgi autoantigen, golgin subfamily b, macrogolgin 1
chr1_-_183369529 1.57 ENSMUST00000069922.5
melanoma inhibitory activity 3
chr13_-_55415166 1.57 ENSMUST00000054146.3
profilin 3
chr5_+_30869623 1.54 ENSMUST00000114716.1
transmembrane protein 214
chr17_-_26199008 1.53 ENSMUST00000142410.1
ENSMUST00000120333.1
ENSMUST00000039113.7
protein disulfide isomerase associated 2
chr7_+_139212974 1.53 ENSMUST00000016124.8
leucine rich repeat containing 27
chr19_+_5088534 1.51 ENSMUST00000025811.4
Yip1 interacting factor homolog A (S. cerevisiae)
chr9_-_103202113 1.50 ENSMUST00000035157.8
signal recognition particle receptor, B subunit
chr10_+_42761483 1.48 ENSMUST00000019937.4
SEC63-like (S. cerevisiae)
chr12_-_36042476 1.44 ENSMUST00000020896.8
tetraspanin 13
chr11_-_86807624 1.43 ENSMUST00000018569.7
DEAH (Asp-Glu-Ala-His) box polypeptide 40
chr12_+_13269111 1.42 ENSMUST00000042953.8
neuroblastoma amplified sequence
chr2_+_70661556 1.40 ENSMUST00000112201.1
ENSMUST00000028509.4
ENSMUST00000133432.1
ENSMUST00000112205.1
golgi reassembly stacking protein 2
chr5_+_30869579 1.39 ENSMUST00000046349.7
transmembrane protein 214
chr3_-_97767916 1.37 ENSMUST00000045243.8
phosphodiesterase 4D interacting protein (myomegalin)
chr1_-_13589717 1.36 ENSMUST00000027068.4
translocating chain-associating membrane protein 1
chr4_+_137594140 1.32 ENSMUST00000105840.1
ENSMUST00000055131.6
ENSMUST00000105839.1
ENSMUST00000105838.1
ubiquitin specific peptidase 48
chr3_+_96697100 1.32 ENSMUST00000107077.3
protein inhibitor of activated STAT 3
chrX_+_56454871 1.32 ENSMUST00000039374.2
ENSMUST00000101553.2
DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B
chr6_-_4086914 1.32 ENSMUST00000049166.4
blocked early in transport 1 homolog (S. cerevisiae)
chr6_-_88518760 1.31 ENSMUST00000032168.5
Sec61 alpha 1 subunit (S. cerevisiae)
chr3_-_108562153 1.29 ENSMUST00000106622.2
transmembrane protein 167B
chr7_-_122067263 1.29 ENSMUST00000033159.3
glutamyl-tRNA synthetase 2 (mitochondrial)(putative)
chr7_+_116504409 1.28 ENSMUST00000183175.1
nucleobindin 2
chr17_-_64331817 1.28 ENSMUST00000172733.1
ENSMUST00000172818.1
praja 2, RING-H2 motif containing
chr5_-_115158169 1.26 ENSMUST00000053271.5
ENSMUST00000112121.1
malectin
chr7_+_116504363 1.26 ENSMUST00000032895.8
nucleobindin 2
chr14_-_79301623 1.24 ENSMUST00000022595.7
regulator of cell cycle
chr6_+_88084473 1.24 ENSMUST00000032143.6
ribophorin I
chr9_+_57560934 1.23 ENSMUST00000045791.9
secretory carrier membrane protein 2
chr3_-_108086590 1.21 ENSMUST00000102638.1
ENSMUST00000102637.1
adenosine monophosphate deaminase 2
chr15_-_102136225 1.20 ENSMUST00000154032.1
SPRY domain containing 3
chr4_-_132144486 1.20 ENSMUST00000056336.1
opioid receptor, delta 1
chr16_-_11134624 1.15 ENSMUST00000038424.7
thioredoxin domain containing 11
chr9_+_104063376 1.14 ENSMUST00000120854.1
acyl-Coenzyme A dehydrogenase family, member 11
chr10_+_41519493 1.11 ENSMUST00000019962.8
CD164 antigen
chr5_+_110176640 1.11 ENSMUST00000112512.1
golgi autoantigen, golgin subfamily a, 3
chr7_+_139213003 1.11 ENSMUST00000156768.1
leucine rich repeat containing 27
chr11_-_96916448 1.10 ENSMUST00000103152.4
CDK5 regulatory subunit associated protein 3
chr2_-_91070180 1.09 ENSMUST00000153367.1
ENSMUST00000079976.3
solute carrier family 39 (metal ion transporter), member 13
chr2_-_144011202 1.08 ENSMUST00000016072.5
ENSMUST00000037875.5
ribosome binding protein 1
chr6_+_87042838 1.08 ENSMUST00000113658.1
ENSMUST00000113657.1
ENSMUST00000113655.1
ENSMUST00000032057.7
glutamine fructose-6-phosphate transaminase 1
chr11_-_20741580 1.07 ENSMUST00000035350.5
aftiphilin
chr14_-_60086832 1.07 ENSMUST00000080368.5
ATPase, aminophospholipid transporter-like, class I, type 8A, member 2
chr17_+_29490812 1.04 ENSMUST00000024811.6
proviral integration site 1
chr4_+_43441939 1.04 ENSMUST00000060864.6
testis specific protein kinase 1
chr2_-_91070283 1.00 ENSMUST00000111436.2
ENSMUST00000073575.5
solute carrier family 39 (metal ion transporter), member 13
chrX_-_155623325 1.00 ENSMUST00000038665.5
patched domain containing 1
chr10_-_24101951 0.99 ENSMUST00000170267.1
trace amine-associated receptor 8C
chr11_-_72796028 0.95 ENSMUST00000156294.1
cytochrome b5 domain containing 2
chr4_-_151861698 0.94 ENSMUST00000049790.7
calmodulin binding transcription activator 1
chr11_-_68853119 0.94 ENSMUST00000018880.7
nuclear distribution gene E-like homolog 1 (A. nidulans)
chr4_-_151861762 0.92 ENSMUST00000097774.2
calmodulin binding transcription activator 1
chr6_+_29348069 0.92 ENSMUST00000173216.1
ENSMUST00000031779.10
ENSMUST00000090481.7
calumenin
chr5_-_35679416 0.91 ENSMUST00000114233.2
HtrA serine peptidase 3
chr2_+_155133501 0.91 ENSMUST00000029126.8
ENSMUST00000109685.1
itchy, E3 ubiquitin protein ligase
chr3_+_96697076 0.91 ENSMUST00000162778.2
ENSMUST00000064900.9
protein inhibitor of activated STAT 3
chr4_-_134000857 0.90 ENSMUST00000105887.1
ENSMUST00000012262.5
ENSMUST00000144668.1
ENSMUST00000105889.3
dehydrodolichyl diphosphate synthase
chr11_-_96916366 0.89 ENSMUST00000144731.1
ENSMUST00000127048.1
CDK5 regulatory subunit associated protein 3
chr13_-_55321928 0.89 ENSMUST00000035242.7
RAB24, member RAS oncogene family
chr3_+_123267445 0.88 ENSMUST00000047923.7
Sec24 related gene family, member D (S. cerevisiae)
chr11_-_96916407 0.88 ENSMUST00000130774.1
CDK5 regulatory subunit associated protein 3
chr3_-_65392579 0.88 ENSMUST00000029414.5
signal sequence receptor, gamma
chr4_-_129641060 0.87 ENSMUST00000046425.9
ENSMUST00000133803.1
taxilin alpha
chr19_+_8898090 0.87 ENSMUST00000096246.3
alpha glucosidase 2 alpha neutral subunit
chr2_-_155692317 0.87 ENSMUST00000103140.4
transient receptor potential cation channel, subfamily C, member 4 associated protein
chr9_-_44767792 0.85 ENSMUST00000034607.9
archain 1
chr4_-_43000451 0.84 ENSMUST00000030164.7
valosin containing protein
chr1_-_93478785 0.83 ENSMUST00000170883.1
high density lipoprotein (HDL) binding protein
chr12_-_59011996 0.81 ENSMUST00000021375.5
SEC23A (S. cerevisiae)
chr7_-_121035096 0.80 ENSMUST00000065740.2
predicted gene 9905
chr14_-_75754475 0.79 ENSMUST00000049168.7
component of oligomeric golgi complex 3
chr3_-_108562349 0.78 ENSMUST00000090546.5
transmembrane protein 167B
chr1_+_119526125 0.77 ENSMUST00000183952.1
Transmembrane protein 185B
chr5_+_110176868 0.77 ENSMUST00000139611.1
ENSMUST00000031477.8
golgi autoantigen, golgin subfamily a, 3
chr7_+_122067164 0.77 ENSMUST00000033158.4
ubiquitin family domain containing 1
chr11_-_72795801 0.76 ENSMUST00000079681.5
cytochrome b5 domain containing 2
chr6_-_82774448 0.73 ENSMUST00000000642.4
hexokinase 2
chr10_+_85102627 0.73 ENSMUST00000095383.4
expressed sequence AI597468
chr2_-_39065505 0.72 ENSMUST00000039165.8
golgi autoantigen, golgin subfamily a, 1
chr11_+_54100924 0.69 ENSMUST00000093107.5
ENSMUST00000019050.5
ENSMUST00000174616.1
ENSMUST00000129499.1
ENSMUST00000126840.1
procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha II polypeptide
chr7_-_127393604 0.68 ENSMUST00000165495.1
ENSMUST00000106303.2
ENSMUST00000074249.6
RIKEN cDNA E430018J23 gene
chr12_+_59130767 0.66 ENSMUST00000175877.1
CTAGE family, member 5
chrX_+_56346390 0.65 ENSMUST00000101560.3
zinc finger protein 449
chr15_+_23036449 0.65 ENSMUST00000164787.1
cadherin 18
chr12_+_69184158 0.63 ENSMUST00000060579.8
mannoside acetylglucosaminyltransferase 2
chr19_+_46761578 0.63 ENSMUST00000077666.4
ENSMUST00000099373.4
cyclin M2
chr3_-_65392546 0.62 ENSMUST00000119896.1
signal sequence receptor, gamma
chr16_-_11134601 0.60 ENSMUST00000118362.1
ENSMUST00000118679.1
thioredoxin domain containing 11
chr5_+_124540695 0.59 ENSMUST00000060226.4
transmembrane emp24 domain trafficking protein 2
chr5_-_72559599 0.58 ENSMUST00000074948.4
ENSMUST00000087216.5
nuclear transcription factor, X-box binding-like 1
chr5_+_144190284 0.57 ENSMUST00000060747.7
basic helix-loop-helix family, member a15
chr4_-_11386679 0.56 ENSMUST00000043781.7
ENSMUST00000108310.1
epithelial splicing regulatory protein 1
chr7_+_28693032 0.56 ENSMUST00000151227.1
ENSMUST00000108281.1
F-box protein 27
chr8_+_25720054 0.55 ENSMUST00000068916.8
ENSMUST00000139836.1
phosphatidic acid phosphatase type 2 domain containing 1B
chr10_-_78753046 0.55 ENSMUST00000105383.2
coiled-coil domain containing 105
chr13_+_73937799 0.54 ENSMUST00000099384.2
bromodomain containing 9
chr11_-_20741447 0.54 ENSMUST00000177543.1
aftiphilin
chr13_+_81657732 0.53 ENSMUST00000049055.6
LysM, putative peptidoglycan-binding, domain containing 3
chr19_-_6909599 0.51 ENSMUST00000173091.1
peroxiredoxin 5
chr16_+_52031549 0.51 ENSMUST00000114471.1
Casitas B-lineage lymphoma b
chr2_+_121140407 0.49 ENSMUST00000028702.3
ENSMUST00000110665.1
adenosine deaminase-like
chr17_-_47833169 0.48 ENSMUST00000131971.1
ENSMUST00000129360.1
ENSMUST00000113280.1
ENSMUST00000132125.1
MyoD family inhibitor
chr4_-_151861667 0.48 ENSMUST00000169423.2
calmodulin binding transcription activator 1
chr4_-_43562397 0.48 ENSMUST00000030187.7
talin 1
chr4_-_11386757 0.47 ENSMUST00000108313.1
ENSMUST00000108311.2
epithelial splicing regulatory protein 1
chr10_-_24092320 0.47 ENSMUST00000092654.2
trace amine-associated receptor 8B
chr17_-_51831884 0.47 ENSMUST00000124222.1
special AT-rich sequence binding protein 1
chr2_-_121140371 0.46 ENSMUST00000099486.2
leucine carboxyl methyltransferase 2
chr8_+_108714644 0.46 ENSMUST00000043896.8
zinc finger homeobox 3
chr11_-_69948145 0.46 ENSMUST00000179298.1
ENSMUST00000018710.6
ENSMUST00000135437.1
ENSMUST00000141837.2
ENSMUST00000142500.1
solute carrier family 2 (facilitated glucose transporter), member 4
chr19_-_41263931 0.45 ENSMUST00000025989.8
transmembrane 9 superfamily member 3
chr7_+_100706623 0.45 ENSMUST00000107042.1
family with sequence similarity 168, member A
chr17_-_47833256 0.44 ENSMUST00000152455.1
ENSMUST00000035375.7
MyoD family inhibitor
chr11_-_68853019 0.44 ENSMUST00000108672.1
nuclear distribution gene E-like homolog 1 (A. nidulans)
chr17_-_25861456 0.43 ENSMUST00000079461.8
ENSMUST00000176923.1
WD repeat domain 90
chr6_-_72958465 0.43 ENSMUST00000114050.1
thymosin, beta 10
chr8_+_71367210 0.43 ENSMUST00000019169.7
unconventional SNARE in the ER 1 homolog (S. cerevisiae)
chr19_+_6276725 0.42 ENSMUST00000025684.3
EH-domain containing 1
chr13_-_100833369 0.41 ENSMUST00000067246.4
solute carrier family 30 (zinc transporter), member 5
chr7_-_126799134 0.40 ENSMUST00000087566.4
aldolase A, fructose-bisphosphate
chr5_+_76974683 0.40 ENSMUST00000101087.3
ENSMUST00000120550.1
signal recognition particle 72
chr7_-_127387113 0.40 ENSMUST00000164345.1
ENSMUST00000049052.3
RIKEN cDNA 9130019O22 gene
chr17_+_34032071 0.39 ENSMUST00000174299.1
ENSMUST00000173554.1
retinoid X receptor beta
chr7_-_81992277 0.38 ENSMUST00000026096.7
basonuclin 1
chr9_+_44379490 0.37 ENSMUST00000066601.6
hypoxia up-regulated 1
chr1_+_172082509 0.36 ENSMUST00000135192.1
coatomer protein complex subunit alpha
chr2_+_121140498 0.36 ENSMUST00000119031.1
ENSMUST00000110662.2
adenosine deaminase-like
chr17_-_35201996 0.36 ENSMUST00000167924.1
ENSMUST00000025263.8
tumor necrosis factor
chr5_+_124541296 0.36 ENSMUST00000124529.1
transmembrane emp24 domain trafficking protein 2
chr1_-_172082757 0.36 ENSMUST00000003550.4
nicastrin
chr9_-_21091974 0.34 ENSMUST00000115487.1
ribonucleoprotein, PTB-binding 1
chr17_-_56183887 0.34 ENSMUST00000019723.7
DNA segment, Chr 17, Wayne State University 104, expressed
chr4_+_44756553 0.33 ENSMUST00000107824.2
zinc finger, CCHC domain containing 7
chr11_-_100970887 0.32 ENSMUST00000060792.5
polymerase I and transcript release factor
chr4_-_129640959 0.32 ENSMUST00000132217.1
ENSMUST00000130017.1
ENSMUST00000154105.1
taxilin alpha
chr14_+_26638237 0.32 ENSMUST00000112318.3
ADP-ribosylation factor 4
chr2_+_164497518 0.32 ENSMUST00000103101.4
ENSMUST00000117066.1
phosphatidylinositol glycan anchor biosynthesis, class T
chr11_-_59228162 0.31 ENSMUST00000163300.1
ENSMUST00000061242.7
ADP-ribosylation factor 1
chr8_+_71366848 0.30 ENSMUST00000110053.2
ENSMUST00000110054.1
ENSMUST00000139541.1
unconventional SNARE in the ER 1 homolog (S. cerevisiae)
chr10_+_24076500 0.30 ENSMUST00000051133.5
trace amine-associated receptor 8A
chr3_+_89246397 0.29 ENSMUST00000168900.1
keratinocyte associated protein 2
chr6_-_72958097 0.28 ENSMUST00000114049.1
thymosin, beta 10
chr19_-_5771376 0.26 ENSMUST00000025890.8
SCY1-like 1 (S. cerevisiae)
chr1_+_92910758 0.26 ENSMUST00000027487.8
arginyl aminopeptidase (aminopeptidase B)-like 1
chr19_+_8819401 0.26 ENSMUST00000096753.3
heterogeneous nuclear ribonucleoprotein U-like 2
chr5_+_120431770 0.26 ENSMUST00000031591.7
LIM homeobox protein 5
chr9_+_44379536 0.26 ENSMUST00000161318.1
ENSMUST00000160902.1
hypoxia up-regulated 1
chrX_+_20658326 0.25 ENSMUST00000089217.4
ubiquitin-like modifier activating enzyme 1

Network of associatons between targets according to the STRING database.

First level regulatory network of Xbp1_Creb3l1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 7.6 GO:0006621 protein retention in ER lumen(GO:0006621)
1.0 3.0 GO:0034224 cellular response to zinc ion starvation(GO:0034224)
1.0 12.6 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.8 2.5 GO:0070093 negative regulation of glucagon secretion(GO:0070093) positive regulation of testosterone secretion(GO:2000845)
0.7 2.1 GO:0006990 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990) establishment of viral latency(GO:0019043) release from viral latency(GO:0019046)
0.7 3.3 GO:0008291 acetylcholine metabolic process(GO:0008291) acetate ester metabolic process(GO:1900619)
0.6 1.8 GO:0060574 bronchiole development(GO:0060435) intestinal epithelial cell maturation(GO:0060574)
0.5 4.9 GO:0071569 protein ufmylation(GO:0071569)
0.5 6.6 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.4 2.1 GO:0097167 circadian regulation of translation(GO:0097167)
0.4 1.2 GO:0003331 regulation of extracellular matrix constituent secretion(GO:0003330) positive regulation of extracellular matrix constituent secretion(GO:0003331)
0.4 1.7 GO:0010360 negative regulation of anion channel activity(GO:0010360) regulation of dense core granule biogenesis(GO:2000705)
0.4 7.4 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.3 1.9 GO:0070417 negative regulation of translation in response to stress(GO:0032055) cellular response to cold(GO:0070417)
0.3 0.9 GO:0035519 protein K29-linked ubiquitination(GO:0035519)
0.3 1.4 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.3 0.9 GO:0021691 cerebellar Purkinje cell layer maturation(GO:0021691)
0.3 0.8 GO:0006154 adenosine catabolic process(GO:0006154)
0.3 0.8 GO:0042726 flavin-containing compound metabolic process(GO:0042726)
0.2 1.2 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.2 2.8 GO:0060628 regulation of ER to Golgi vesicle-mediated transport(GO:0060628)
0.2 0.7 GO:1905053 regulation of base-excision repair(GO:1905051) positive regulation of base-excision repair(GO:1905053)
0.2 1.3 GO:0039019 pronephric nephron development(GO:0039019)
0.2 1.1 GO:0006041 glucosamine metabolic process(GO:0006041)
0.2 0.6 GO:0031590 wybutosine metabolic process(GO:0031590) wybutosine biosynthetic process(GO:0031591)
0.2 8.6 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.2 3.8 GO:0007289 spermatid nucleus differentiation(GO:0007289)
0.2 4.1 GO:0044144 regulation of growth of symbiont in host(GO:0044126) modulation of growth of symbiont involved in interaction with host(GO:0044144)
0.2 1.3 GO:0070127 tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.2 2.7 GO:0060510 Type II pneumocyte differentiation(GO:0060510)
0.2 0.5 GO:0060785 regulation of apoptosis involved in tissue homeostasis(GO:0060785)
0.2 2.4 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.2 0.5 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.2 1.2 GO:0032261 purine nucleotide salvage(GO:0032261) IMP salvage(GO:0032264)
0.1 1.6 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.1 0.7 GO:1904925 negative regulation of mitochondrial membrane permeability(GO:0035795) positive regulation of macromitophagy(GO:1901526) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925)
0.1 0.4 GO:2001137 positive regulation of endocytic recycling(GO:2001137)
0.1 5.0 GO:1903146 regulation of mitophagy(GO:1903146)
0.1 1.0 GO:2000138 positive regulation of cell proliferation involved in heart morphogenesis(GO:2000138)
0.1 0.5 GO:0002669 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.1 2.2 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.1 1.7 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.1 1.0 GO:0032525 somite rostral/caudal axis specification(GO:0032525)
0.1 0.7 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.1 0.8 GO:0016093 polyprenol metabolic process(GO:0016093)
0.1 0.6 GO:1903297 regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903297) negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903298) intrinsic apoptotic signaling pathway in response to hypoxia(GO:1990144)
0.1 1.6 GO:0045793 positive regulation of cell size(GO:0045793)
0.1 0.3 GO:0021937 cerebellar Purkinje cell-granule cell precursor cell signaling involved in regulation of granule cell precursor cell proliferation(GO:0021937)
0.1 1.5 GO:1902175 regulation of oxidative stress-induced intrinsic apoptotic signaling pathway(GO:1902175)
0.1 0.5 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.1 0.2 GO:0072272 proximal/distal pattern formation involved in metanephric nephron development(GO:0072272)
0.1 1.1 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.1 0.3 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.0 1.0 GO:0021794 thalamus development(GO:0021794)
0.0 1.2 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.0 0.9 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.4 GO:0061088 sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
0.0 1.3 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 0.9 GO:0060707 trophoblast giant cell differentiation(GO:0060707)
0.0 1.5 GO:0010259 multicellular organism aging(GO:0010259)
0.0 0.4 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.6 GO:0048312 mitochondrial calcium ion transport(GO:0006851) intracellular distribution of mitochondria(GO:0048312)
0.0 0.6 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.0 0.2 GO:0006177 GMP biosynthetic process(GO:0006177)
0.0 0.2 GO:0032596 protein transport into membrane raft(GO:0032596)
0.0 0.5 GO:0015693 magnesium ion transport(GO:0015693)
0.0 1.5 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.0 0.4 GO:0007220 Notch receptor processing(GO:0007220)
0.0 0.5 GO:0043374 CD8-positive, alpha-beta T cell differentiation(GO:0043374)
0.0 1.9 GO:0061077 chaperone-mediated protein folding(GO:0061077)
0.0 1.6 GO:0032233 positive regulation of actin filament bundle assembly(GO:0032233)
0.0 0.5 GO:0044381 glucose import in response to insulin stimulus(GO:0044381)
0.0 1.1 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.3 GO:0018195 peptidyl-arginine modification(GO:0018195)
0.0 0.2 GO:0003085 negative regulation of systemic arterial blood pressure(GO:0003085)
0.0 0.2 GO:2000653 regulation of genetic imprinting(GO:2000653)
0.0 0.9 GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway(GO:0030512)
0.0 1.4 GO:0007030 Golgi organization(GO:0007030)
0.0 0.1 GO:2000680 regulation of rubidium ion transport(GO:2000680)
0.0 0.4 GO:0055012 ventricular cardiac muscle cell differentiation(GO:0055012)
0.0 1.3 GO:0016579 protein deubiquitination(GO:0016579)
0.0 5.5 GO:0007283 spermatogenesis(GO:0007283)
0.0 0.1 GO:0043982 histone H4-K5 acetylation(GO:0043981) histone H4-K8 acetylation(GO:0043982)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0032783 ELL-EAF complex(GO:0032783)
0.5 1.4 GO:0070939 Dsl1p complex(GO:0070939)
0.4 6.3 GO:0030126 COPI vesicle coat(GO:0030126)
0.4 1.6 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.4 3.2 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.4 8.1 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.4 1.9 GO:0090498 extrinsic component of Golgi membrane(GO:0090498)
0.3 0.8 GO:1990730 VCP-NSFL1C complex(GO:1990730)
0.3 3.3 GO:0043083 synaptic cleft(GO:0043083)
0.2 0.4 GO:0020018 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.2 1.1 GO:0071256 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.2 2.6 GO:0017119 Golgi transport complex(GO:0017119)
0.2 9.5 GO:0031201 SNARE complex(GO:0031201)
0.2 3.9 GO:0005797 Golgi medial cisterna(GO:0005797)
0.2 0.7 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.2 1.4 GO:0060053 neurofilament cytoskeleton(GO:0060053)
0.1 1.3 GO:0030137 COPI-coated vesicle(GO:0030137)
0.1 1.5 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.1 1.6 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.1 3.2 GO:0005801 cis-Golgi network(GO:0005801)
0.1 1.5 GO:0030134 ER to Golgi transport vesicle(GO:0030134)
0.1 0.9 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.1 0.3 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.1 0.4 GO:0070765 gamma-secretase complex(GO:0070765)
0.0 2.9 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 1.2 GO:0032590 dendrite membrane(GO:0032590)
0.0 1.3 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 65.3 GO:0005783 endoplasmic reticulum(GO:0005783)
0.0 0.5 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.6 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.1 GO:0097487 multivesicular body, internal vesicle(GO:0097487)
0.0 0.5 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.1 GO:0072487 MSL complex(GO:0072487)
0.0 0.4 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 2.4 GO:0055037 recycling endosome(GO:0055037)
0.0 0.9 GO:0005776 autophagosome(GO:0005776)
0.0 2.0 GO:0043679 axon terminus(GO:0043679)
0.0 3.6 GO:0016323 basolateral plasma membrane(GO:0016323)
0.0 12.8 GO:0005794 Golgi apparatus(GO:0005794)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.9 7.6 GO:0046923 ER retention sequence binding(GO:0046923)
0.8 3.3 GO:0004104 cholinesterase activity(GO:0004104)
0.7 2.1 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.6 1.7 GO:0004698 calcium-dependent protein kinase C activity(GO:0004698)
0.5 1.6 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.5 2.0 GO:0008184 glycogen phosphorylase activity(GO:0008184)
0.5 1.9 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.4 1.1 GO:0017099 very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099)
0.3 10.8 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.3 1.2 GO:0004985 opioid receptor activity(GO:0004985)
0.3 1.4 GO:0070012 oligopeptidase activity(GO:0070012)
0.2 2.2 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.2 1.8 GO:0001594 trace-amine receptor activity(GO:0001594)
0.2 0.8 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.2 8.2 GO:0005484 SNAP receptor activity(GO:0005484)
0.2 0.5 GO:0072541 peroxynitrite reductase activity(GO:0072541)
0.2 2.3 GO:0008641 small protein activating enzyme activity(GO:0008641)
0.2 0.6 GO:0003880 protein C-terminal carboxyl O-methyltransferase activity(GO:0003880)
0.2 1.2 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 3.7 GO:0015248 sterol transporter activity(GO:0015248)
0.1 1.5 GO:0004576 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.1 3.6 GO:0070566 adenylyltransferase activity(GO:0070566)
0.1 3.1 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.1 2.4 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.1 2.0 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 0.9 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.1 1.9 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1 10.2 GO:0000149 SNARE binding(GO:0000149)
0.1 0.7 GO:0008865 fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.1 0.5 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.1 1.0 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.1 1.7 GO:0042288 MHC class I protein binding(GO:0042288)
0.1 1.5 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.1 0.6 GO:0005047 signal recognition particle binding(GO:0005047)
0.1 2.2 GO:0019789 SUMO transferase activity(GO:0019789)
0.1 0.9 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.1 1.3 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.1 2.9 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 0.8 GO:0004000 adenosine deaminase activity(GO:0004000)
0.1 0.5 GO:0030274 LIM domain binding(GO:0030274)
0.1 4.8 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.1 0.9 GO:0004659 prenyltransferase activity(GO:0004659)
0.1 0.3 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.1 33.0 GO:0005509 calcium ion binding(GO:0005509)
0.1 0.4 GO:0030375 thyroid hormone receptor coactivator activity(GO:0030375)
0.1 0.4 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 1.5 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 1.1 GO:0008483 transaminase activity(GO:0008483)
0.0 0.2 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.0 1.6 GO:0030276 clathrin binding(GO:0030276)
0.0 2.0 GO:0070888 E-box binding(GO:0070888)
0.0 0.5 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.9 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 1.2 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.3 GO:0016004 phospholipase activator activity(GO:0016004) lipase activator activity(GO:0060229)
0.0 2.8 GO:0008565 protein transporter activity(GO:0008565)
0.0 1.1 GO:0016875 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.0 0.7 GO:0003785 actin monomer binding(GO:0003785)
0.0 1.4 GO:0003724 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004)
0.0 1.9 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 1.7 GO:0020037 heme binding(GO:0020037)
0.0 0.2 GO:0034046 poly(G) binding(GO:0034046)
0.0 0.1 GO:0043996 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)
0.0 0.1 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 1.3 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 0.3 GO:0070006 metalloaminopeptidase activity(GO:0070006)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.2 ST JAK STAT PATHWAY Jak-STAT Pathway
0.1 3.9 PID ARF 3PATHWAY Arf1 pathway
0.1 2.1 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.1 2.1 ST G ALPHA S PATHWAY G alpha s Pathway
0.1 1.7 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 1.0 PID IL5 PATHWAY IL5-mediated signaling events
0.0 2.9 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 3.8 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 1.8 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 1.7 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 1.0 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.5 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 0.4 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 4.7 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 1.0 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.5 PID CASPASE PATHWAY Caspase cascade in apoptosis

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 6.1 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.4 8.8 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.3 15.2 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.2 3.2 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.2 1.7 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1 2.1 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.1 0.9 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.1 3.3 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.1 1.7 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.1 3.7 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.1 1.9 REACTOME PERK REGULATED GENE EXPRESSION Genes involved in PERK regulated gene expression
0.1 3.1 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.1 1.1 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 1.0 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 2.0 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 2.1 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 1.0 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 4.7 REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.0 0.5 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.4 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.4 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.0 0.6 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0 0.6 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.7 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.0 1.4 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 1.4 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.5 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.3 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.2 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis