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2D miR_HR1_12

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Results for Evx2

Z-value: 0.34

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Transcription factors associated with Evx2

Gene Symbol Gene ID Gene Info
ENSMUSG00000001815.9 even-skipped homeobox 2

Activity profile of Evx2 motif

Sorted Z-values of Evx2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr6_+_122626410 0.35 ENSMUST00000049644.2
developmental pluripotency-associated 3
chr3_-_15575065 0.33 ENSMUST00000091319.4
signal-regulatory protein beta 1B
chr16_-_38800193 0.27 ENSMUST00000057767.4
uroplakin 1B
chr1_+_91801453 0.26 ENSMUST00000007949.3
twist basic helix-loop-helix transcription factor 2
chr2_+_91256813 0.26 ENSMUST00000144394.1
ENSMUST00000028694.5
ENSMUST00000168916.1
ENSMUST00000156919.1
protein kinase C and casein kinase substrate in neurons 3
chr11_-_100762928 0.24 ENSMUST00000107360.2
ENSMUST00000055083.3
hypocretin
chr13_+_51645232 0.23 ENSMUST00000075853.5
CDC28 protein kinase regulatory subunit 2
chr1_+_172555932 0.23 ENSMUST00000061835.3
V-set and immunoglobulin domain containing 8
chr2_+_91257323 0.20 ENSMUST00000111349.2
ENSMUST00000131711.1
protein kinase C and casein kinase substrate in neurons 3
chr1_+_36761847 0.18 ENSMUST00000027291.4
zeta-chain (TCR) associated protein kinase
chr14_-_59365410 0.18 ENSMUST00000161031.1
ENSMUST00000160425.1
PHD finger protein 11D
chr14_+_62292475 0.17 ENSMUST00000166879.1
ribonuclease H2, subunit B
chr2_+_119047116 0.14 ENSMUST00000152380.1
ENSMUST00000099542.2
cancer susceptibility candidate 5
chr15_-_9529868 0.14 ENSMUST00000003981.4
interleukin 7 receptor
chr19_-_5560570 0.13 ENSMUST00000025861.1
OVO homolog-like 1 (Drosophila)
chr2_-_155074447 0.12 ENSMUST00000137242.1
ENSMUST00000054607.9
S-adenosylhomocysteine hydrolase
chr4_-_132345686 0.11 ENSMUST00000030726.6
regulator of chromosome condensation 1
chr11_+_35121126 0.11 ENSMUST00000069837.3
slit homolog 3 (Drosophila)
chr2_+_119047129 0.10 ENSMUST00000153300.1
ENSMUST00000028799.5
cancer susceptibility candidate 5
chr4_-_132345715 0.10 ENSMUST00000084250.4
regulator of chromosome condensation 1
chr19_+_47067721 0.10 ENSMUST00000026027.5
TAF5 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr5_-_98030727 0.09 ENSMUST00000031281.9
anthrax toxin receptor 2
chr19_+_41933464 0.09 ENSMUST00000026154.7
zinc finger, DHHC domain containing 16
chr7_-_44257378 0.09 ENSMUST00000107945.1
ENSMUST00000118216.1
acid phosphatase, testicular
chr11_+_116843278 0.09 ENSMUST00000106370.3
methyltransferase like 23
chr11_-_120378692 0.08 ENSMUST00000026448.9
RIKEN cDNA 2310003H01 gene
chr16_-_45724600 0.08 ENSMUST00000096057.4
transgelin 3
chr9_+_47530173 0.07 ENSMUST00000114548.1
ENSMUST00000152459.1
ENSMUST00000143026.1
ENSMUST00000085909.2
ENSMUST00000114547.1
ENSMUST00000034581.3
cell adhesion molecule 1
chr7_-_143460989 0.07 ENSMUST00000167912.1
ENSMUST00000037287.6
cyclin-dependent kinase inhibitor 1C (P57)
chr11_+_116657106 0.06 ENSMUST00000116318.2
predicted gene 11744
chr14_-_59365465 0.06 ENSMUST00000095157.4
PHD finger protein 11D
chr15_-_58034289 0.06 ENSMUST00000100655.3
RIKEN cDNA 9130401M01 gene
chr10_+_70175011 0.06 ENSMUST00000156001.1
ENSMUST00000135607.1
coiled-coil domain containing 6
chr9_-_107679592 0.06 ENSMUST00000010205.7
guanine nucleotide binding protein, alpha transducing 1
chrM_+_7759 0.05 ENSMUST00000082407.1
ENSMUST00000082408.1
mitochondrially encoded ATP synthase 8
mitochondrially encoded ATP synthase 6
chr2_+_69822370 0.05 ENSMUST00000053087.3
kelch-like 23
chr11_-_65269941 0.04 ENSMUST00000102635.3
myocardin
chr5_-_84417359 0.04 ENSMUST00000113401.1
Eph receptor A5
chr8_-_35495487 0.04 ENSMUST00000033927.6
exoribonuclease 1
chr8_-_31168699 0.04 ENSMUST00000033983.4
MAK16 homolog (S. cerevisiae)
chr4_+_140701466 0.04 ENSMUST00000038893.5
ENSMUST00000138808.1
regulator of chromosome condensation 2
chr13_+_38204928 0.03 ENSMUST00000091641.5
ENSMUST00000178564.1
small nuclear ribonucleoprotein 48 (U11/U12)
chrM_+_10167 0.03 ENSMUST00000082414.1
mitochondrially encoded NADH dehydrogenase 4
chr16_-_42340595 0.03 ENSMUST00000102817.4
growth associated protein 43
chr17_-_47834682 0.03 ENSMUST00000066368.6
MyoD family inhibitor
chr18_+_24603952 0.03 ENSMUST00000025120.6
elongator acetyltransferase complex subunit 2
chr18_+_77332394 0.02 ENSMUST00000148341.1
lipoxygenase homology domains 1
chr2_-_150255591 0.02 ENSMUST00000063463.5
predicted gene 21994
chr2_+_154548888 0.02 ENSMUST00000045116.4
ENSMUST00000109709.3
RIKEN cDNA 1700003F12 gene
chr9_-_66514567 0.02 ENSMUST00000056890.8
F-box and leucine-rich repeat protein 22
chr11_-_113710017 0.02 ENSMUST00000018871.1
cleavage and polyadenylation specific factor 4-like
chr2_-_27475622 0.02 ENSMUST00000138693.1
ENSMUST00000113941.2
ENSMUST00000077737.6
bromodomain containing 3
chr3_+_121291725 0.02 ENSMUST00000039442.7
asparagine-linked glycosylation 14
chr3_-_130709419 0.02 ENSMUST00000043937.7
oligosaccharyltransferase complex subunit
chr11_-_113709520 0.02 ENSMUST00000173655.1
ENSMUST00000100248.4
cleavage and polyadenylation specific factor 4-like
chr1_-_184999549 0.02 ENSMUST00000027929.4
MAP/microtubule affinity-regulating kinase 1
chr6_+_116650674 0.01 ENSMUST00000067354.5
ENSMUST00000178241.1
RIKEN cDNA 8430408G22 gene
chr2_+_164613519 0.01 ENSMUST00000094346.2
WAP four-disulfide core domain 6B
chr19_-_41933276 0.01 ENSMUST00000075280.4
ENSMUST00000112123.2
exosome component 1
chr3_+_94837533 0.01 ENSMUST00000107270.2
pogo transposable element with ZNF domain
chr7_+_6222278 0.01 ENSMUST00000072662.5
ENSMUST00000155314.1
zinc finger and SCAN domain containing 5B
chr10_-_80701811 0.01 ENSMUST00000003438.9
MOB kinase activator 3A
chr10_-_8886033 0.01 ENSMUST00000015449.5
SAM and SH3 domain containing 1
chr18_-_24603791 0.00 ENSMUST00000070726.3
solute carrier family 39 (metal ion transporter), member 6
chr10_+_80264942 0.00 ENSMUST00000105362.1
ENSMUST00000105361.3
DAZ associated protein 1

Network of associatons between targets according to the STRING database.

First level regulatory network of Evx2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:1901535 regulation of DNA demethylation(GO:1901535) negative regulation of DNA demethylation(GO:1901536)
0.0 0.1 GO:0044771 meiotic cell cycle phase transition(GO:0044771) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.0 0.2 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.0 0.2 GO:0043366 beta selection(GO:0043366)
0.0 0.1 GO:0002439 chronic inflammatory response to antigenic stimulus(GO:0002439)
0.0 0.3 GO:0061303 cornea development in camera-type eye(GO:0061303)
0.0 0.1 GO:0042271 unidimensional cell growth(GO:0009826) susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.0 0.1 GO:0070100 negative regulation of chemokine-mediated signaling pathway(GO:0070100)
0.0 0.5 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.1 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.0 0.0 GO:2000724 regulation of phenotypic switching(GO:1900239) negative regulation of vascular associated smooth muscle cell migration(GO:1904753) regulation of cardiac vascular smooth muscle cell differentiation(GO:2000722) positive regulation of cardiac vascular smooth muscle cell differentiation(GO:2000724)
0.0 0.1 GO:0051342 sensory perception of umami taste(GO:0050917) regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 GO:0001940 male pronucleus(GO:0001940)
0.0 0.2 GO:0032299 ribonuclease H2 complex(GO:0032299)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.0 0.5 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 0.2 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.2 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0 0.1 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.1 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.0 GO:0071207 histone pre-mRNA stem-loop binding(GO:0071207)
0.0 0.2 GO:0005184 neuropeptide hormone activity(GO:0005184)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse