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2D miR_HR1_12

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Results for Nfatc3

Z-value: 0.53

Motif logo

Transcription factors associated with Nfatc3

Gene Symbol Gene ID Gene Info
ENSMUSG00000031902.9 nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Nfatc3mm10_v2_chr8_+_106059562_106059623-0.029.6e-01Click!

Activity profile of Nfatc3 motif

Sorted Z-values of Nfatc3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr10_+_4611971 1.56 ENSMUST00000105590.1
ENSMUST00000067086.7
estrogen receptor 1 (alpha)
chr1_+_172698046 0.69 ENSMUST00000038495.3
C-reactive protein, pentraxin-related
chr5_+_110330697 0.64 ENSMUST00000112481.1
polymerase (DNA directed), epsilon
chr9_+_88327592 0.50 ENSMUST00000034992.6
5' nucleotidase, ecto
chr6_-_85513586 0.45 ENSMUST00000095759.3
early growth response 4
chr3_+_138217814 0.44 ENSMUST00000090171.5
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr1_-_164935522 0.44 ENSMUST00000027860.7
chemokine (C motif) ligand 1
chr5_-_103629279 0.43 ENSMUST00000031263.1
solute carrier family 10 (sodium/bile acid cotransporter family), member 6
chr1_+_91801453 0.41 ENSMUST00000007949.3
twist basic helix-loop-helix transcription factor 2
chr11_-_53634698 0.34 ENSMUST00000020650.1
interleukin 13
chr2_+_122637867 0.32 ENSMUST00000110512.3
expressed sequence AA467197
chr13_+_16014457 0.31 ENSMUST00000164993.1
inhibin beta-A
chr1_-_172895048 0.31 ENSMUST00000027824.5
serum amyloid P-component
chr6_+_21986438 0.30 ENSMUST00000115382.1
cadherin-like and PC-esterase domain containing 1
chr13_+_67863324 0.27 ENSMUST00000078471.5
cDNA sequence BC048507
chr2_+_122637844 0.27 ENSMUST00000047498.8
expressed sequence AA467197
chr8_-_122460666 0.26 ENSMUST00000006762.5
snail homolog 3 (Drosophila)
chr2_-_62573813 0.26 ENSMUST00000174234.1
ENSMUST00000000402.9
ENSMUST00000174448.1
fibroblast activation protein
chrX_+_71555918 0.26 ENSMUST00000072699.6
ENSMUST00000114582.2
ENSMUST00000015361.4
ENSMUST00000088874.3
high mobility group box 3
chr7_+_45621805 0.26 ENSMUST00000033100.4
izumo sperm-egg fusion 1
chr17_-_70851710 0.26 ENSMUST00000166395.2
TGFB-induced factor homeobox 1
chr2_-_121235689 0.25 ENSMUST00000142400.1
transformation related protein 53 binding protein 1
chr17_-_68004075 0.25 ENSMUST00000024840.5
Rho GTPase activating protein 28
chr1_-_180193653 0.24 ENSMUST00000159914.1
aarF domain containing kinase 3
chr5_-_88527841 0.24 ENSMUST00000087033.3
immunoglobulin joining chain
chr11_+_99047311 0.23 ENSMUST00000140772.1
insulin-like growth factor binding protein 4
chr17_-_35516780 0.23 ENSMUST00000160885.1
ENSMUST00000159009.1
ENSMUST00000161012.1
transcription factor 19
chr11_-_82179808 0.23 ENSMUST00000108189.2
ENSMUST00000021043.4
chemokine (C-C motif) ligand 1
chr12_+_91400990 0.23 ENSMUST00000021346.7
ENSMUST00000021343.6
thyroid stimulating hormone receptor
chr2_+_157560078 0.22 ENSMUST00000153739.2
ENSMUST00000173595.1
ENSMUST00000109526.1
ENSMUST00000173839.1
ENSMUST00000173041.1
ENSMUST00000173793.1
ENSMUST00000172487.1
ENSMUST00000088484.5
neuronatin
chr16_-_3718105 0.22 ENSMUST00000023180.7
ENSMUST00000100222.2
Mediterranean fever
chr12_-_69582985 0.22 ENSMUST00000058639.9
methyltransferase like 21D
chr4_+_48049080 0.21 ENSMUST00000153369.1
nuclear receptor subfamily 4, group A, member 3
chr9_+_64235201 0.21 ENSMUST00000039011.3
ubiquitin carboxyl-terminal esterase L4
chr15_+_8109313 0.21 ENSMUST00000163765.1
nucleoporin 155
chr1_+_55237177 0.21 ENSMUST00000061334.8
methionine-tRNA synthetase 2 (mitochondrial)
chr19_-_10101501 0.21 ENSMUST00000025567.7
fatty acid desaturase 2
chr18_+_73863672 0.21 ENSMUST00000134847.1
maestro
chr9_-_29963112 0.21 ENSMUST00000075069.4
neurotrimin
chr1_-_63214543 0.20 ENSMUST00000050536.7
G protein-coupled receptor 1
chr1_+_12718496 0.20 ENSMUST00000088585.3
sulfatase 1
chr9_-_58158498 0.20 ENSMUST00000168864.2
immunoglobulin superfamily containing leucine-rich repeat
chr8_-_84969740 0.19 ENSMUST00000109736.2
ENSMUST00000140561.1
ribonuclease H2, large subunit
chr6_+_21985903 0.19 ENSMUST00000137437.1
ENSMUST00000115383.2
cadherin-like and PC-esterase domain containing 1
chr2_+_3114220 0.19 ENSMUST00000072955.5
family with sequence similarity 171, member A1
chr17_-_45474839 0.18 ENSMUST00000024731.8
spermatogenesis associated, serine-rich 1
chr14_-_16575456 0.18 ENSMUST00000063750.6
retinoic acid receptor, beta
chr7_-_38227975 0.18 ENSMUST00000098513.4
pleckstrin homology domain containing, family F (with FYVE domain) member 1
chr11_-_35980473 0.18 ENSMUST00000018993.6
WW, C2 and coiled-coil domain containing 1
chr11_+_75656103 0.18 ENSMUST00000136935.1
myosin IC
chr11_-_83530505 0.18 ENSMUST00000035938.2
chemokine (C-C motif) ligand 5
chr10_+_7667503 0.18 ENSMUST00000040135.8
nucleoporin 43
chrX_-_7671341 0.17 ENSMUST00000033486.5
proteolipid protein 2
chr5_+_66676098 0.17 ENSMUST00000031131.9
ubiquitin carboxy-terminal hydrolase L1
chr3_-_75270073 0.17 ENSMUST00000039047.4
serine (or cysteine) peptidase inhibitor, clade I, member 2
chr3_+_7612702 0.17 ENSMUST00000181286.1
predicted gene, 16685
chr4_-_141239453 0.17 ENSMUST00000168138.1
RIKEN cDNA C630004L07 gene
chr1_+_162639148 0.17 ENSMUST00000028020.9
myocilin
chr3_-_86548268 0.17 ENSMUST00000077524.3
mab-21-like 2 (C. elegans)
chr3_-_101836223 0.17 ENSMUST00000061831.4
mab-21-like 3 (C. elegans)
chr4_-_82505749 0.16 ENSMUST00000107245.2
ENSMUST00000107246.1
nuclear factor I/B
chr16_-_4559720 0.16 ENSMUST00000005862.7
transcription factor AP4
chr18_-_15718046 0.16 ENSMUST00000053017.6
carbohydrate (N-acetylgalactosamine 4-0) sulfotransferase 9
chr2_+_61711694 0.15 ENSMUST00000028278.7
proteasome (prosome, macropain) 26S subunit, non-ATPase, 14
chr13_+_43370710 0.15 ENSMUST00000066804.4
sirtuin 5
chr17_+_34629533 0.15 ENSMUST00000015620.6
proline-rich transmembrane protein 1
chr11_+_115381906 0.14 ENSMUST00000053288.5
cerebellar degeneration-related protein 2-like
chr5_-_148392810 0.14 ENSMUST00000138257.1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr7_+_100494044 0.14 ENSMUST00000153287.1
uncoupling protein 2 (mitochondrial, proton carrier)
chr5_+_3343893 0.14 ENSMUST00000165117.1
cyclin-dependent kinase 6
chr2_+_86046451 0.14 ENSMUST00000079298.2
olfactory receptor 1034
chr12_-_31654767 0.14 ENSMUST00000020977.2
dihydrouridine synthase 4-like (S. cerevisiae)
chr10_+_82378593 0.14 ENSMUST00000165906.1
predicted gene 4924
chr9_-_71163224 0.14 ENSMUST00000074465.2
aquaporin 9
chr12_-_72917760 0.14 ENSMUST00000110489.2
RIKEN cDNA 4930447C04 gene
chr9_+_65265173 0.14 ENSMUST00000048762.1
cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
chr10_-_61476937 0.14 ENSMUST00000051330.4
RIKEN cDNA D830039M14 gene
chr7_+_100493795 0.14 ENSMUST00000129324.1
uncoupling protein 2 (mitochondrial, proton carrier)
chr16_-_75909272 0.13 ENSMUST00000114239.2
SAM domain, SH3 domain and nuclear localization signals, 1
chr3_+_94377432 0.13 ENSMUST00000107292.1
RAR-related orphan receptor gamma
chr8_+_46010596 0.13 ENSMUST00000110381.2
Lrp2 binding protein
chr3_+_94377505 0.13 ENSMUST00000098877.2
RAR-related orphan receptor gamma
chr17_-_70849644 0.13 ENSMUST00000134654.1
ENSMUST00000172229.1
ENSMUST00000127719.1
TGFB-induced factor homeobox 1
chr19_-_46327121 0.13 ENSMUST00000041391.4
ENSMUST00000096029.5
pleckstrin and Sec7 domain containing
chr14_-_54517353 0.13 ENSMUST00000023873.5
protein arginine N-methyltransferase 5
chr3_-_95995662 0.13 ENSMUST00000123006.1
pleckstrin homology domain containing, family O member 1
chr3_-_61365951 0.13 ENSMUST00000066298.2
RIKEN cDNA B430305J03 gene
chr19_+_41593363 0.13 ENSMUST00000099454.3
expressed sequence AI606181
chr10_+_23949516 0.13 ENSMUST00000045152.4
trace amine-associated receptor 3
chr19_+_53310495 0.13 ENSMUST00000003870.7
Max interacting protein 1
chrX_+_164506320 0.13 ENSMUST00000033756.2
ankyrin repeat and SOCS box-containing 9
chr17_+_34204080 0.12 ENSMUST00000138491.1
transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
chr5_+_53590215 0.12 ENSMUST00000037618.6
recombination signal binding protein for immunoglobulin kappa J region
chr11_-_79530569 0.12 ENSMUST00000103236.3
ENSMUST00000170799.1
ENSMUST00000170422.2
ecotropic viral integration site 2a
ecotropic viral integration site 2b
chr7_+_88278085 0.12 ENSMUST00000032779.5
ENSMUST00000128791.1
cathepsin C
chr2_+_93452796 0.12 ENSMUST00000099693.2
ENSMUST00000162565.1
ENSMUST00000163052.1
predicted gene 10804
chr11_+_59541568 0.12 ENSMUST00000079476.3
NLR family, pyrin domain containing 3
chr17_-_45592485 0.12 ENSMUST00000166119.1
solute carrier family 29 (nucleoside transporters), member 1
chr16_+_13986596 0.12 ENSMUST00000056521.5
ENSMUST00000118412.1
ENSMUST00000131608.1
RIKEN cDNA 2900011O08 gene
chr3_-_95995999 0.12 ENSMUST00000015889.3
pleckstrin homology domain containing, family O member 1
chr1_+_171214013 0.12 ENSMUST00000111328.1
nuclear receptor subfamily 1, group I, member 3
chr9_-_37255730 0.12 ENSMUST00000115068.2
solute carrier family 37 (glycerol-3-phosphate transporter), member 2
chr5_-_17835857 0.12 ENSMUST00000082367.6
CD36 antigen
chr10_-_111997204 0.12 ENSMUST00000074805.5
GLI pathogenesis-related 1 (glioma)
chr13_-_114388057 0.12 ENSMUST00000022286.6
NADH dehydrogenase (ubiquinone) Fe-S protein 4
chr11_-_77151925 0.11 ENSMUST00000130901.1
EF-hand calcium binding domain 5
chr8_-_107403197 0.11 ENSMUST00000003947.8
NAD(P)H dehydrogenase, quinone 1
chr16_+_43508118 0.11 ENSMUST00000114690.1
zinc finger and BTB domain containing 20
chr7_-_45830776 0.11 ENSMUST00000107723.2
ENSMUST00000131384.1
glutamate-rich WD repeat containing 1
chr15_-_77928925 0.11 ENSMUST00000109748.2
ENSMUST00000109747.2
ENSMUST00000100486.5
ENSMUST00000005487.5
thioredoxin 2
chr14_-_7994563 0.11 ENSMUST00000026315.7
deoxyribonuclease 1-like 3
chr9_+_34486125 0.11 ENSMUST00000183580.1
ENSMUST00000115148.2
RP24-225I21.1
kin of IRRE like 3 (Drosophila)
chr17_-_6961156 0.11 ENSMUST00000063683.6
T cell activation GTPase activating protein 1
chr7_+_46847128 0.11 ENSMUST00000005051.4
lactate dehydrogenase A
chr5_-_89457763 0.11 ENSMUST00000049209.8
group specific component
chr19_+_3282901 0.11 ENSMUST00000025745.3
ENSMUST00000025743.6
mitochondrial ribosomal protein L21
chr3_-_59130610 0.11 ENSMUST00000065220.6
ENSMUST00000091112.4
purinergic receptor P2Y, G-protein coupled, 14
chr17_+_47726834 0.11 ENSMUST00000024782.5
ENSMUST00000144955.1
progastricsin (pepsinogen C)
chrX_+_56963325 0.11 ENSMUST00000096431.3
G protein-coupled receptor 112
chr4_-_129578535 0.11 ENSMUST00000052835.8
family with sequence similarity 167, member B
chr17_-_45592569 0.10 ENSMUST00000163492.1
solute carrier family 29 (nucleoside transporters), member 1
chr2_+_84839395 0.10 ENSMUST00000146816.1
ENSMUST00000028469.7
solute carrier family 43, member 1
chr4_-_133872304 0.10 ENSMUST00000157067.2
ribosomal protein S6 kinase polypeptide 1
chr1_+_186967416 0.10 ENSMUST00000045108.1
DNA segment, Chr 1, Pasteur Institute 1
chr1_+_171225054 0.10 ENSMUST00000111321.1
ENSMUST00000005824.5
ENSMUST00000111320.1
ENSMUST00000111319.1
apolipoprotein A-II
chr2_-_25608447 0.10 ENSMUST00000058137.8
RAB, member of RAS oncogene family-like 6
chr9_+_7692086 0.10 ENSMUST00000018767.7
matrix metallopeptidase 7
chr7_+_130577334 0.10 ENSMUST00000059145.7
ENSMUST00000084513.4
transforming, acidic coiled-coil containing protein 2
chr5_-_67099235 0.10 ENSMUST00000012664.8
paired-like homeobox 2b
chr1_-_180193475 0.10 ENSMUST00000160482.1
ENSMUST00000170472.1
aarF domain containing kinase 3
chr7_-_70366735 0.09 ENSMUST00000089565.5
nuclear receptor subfamily 2, group F, member 2
chrX_-_48513518 0.09 ENSMUST00000114945.2
ENSMUST00000037349.7
apoptosis-inducing factor, mitochondrion-associated 1
chr3_-_33083016 0.09 ENSMUST00000078226.3
ENSMUST00000108224.1
peroxisomal biogenesis factor 5-like
chr1_-_171234290 0.09 ENSMUST00000079957.6
Fc receptor, IgE, high affinity I, gamma polypeptide
chrX_-_143827391 0.09 ENSMUST00000087316.5
calpain 6
chr7_-_80402743 0.09 ENSMUST00000122232.1
furin (paired basic amino acid cleaving enzyme)
chr7_-_120670256 0.09 ENSMUST00000033178.2
PDZ domain containing 9
chr6_+_108660772 0.09 ENSMUST00000163617.1
basic helix-loop-helix family, member e40
chr8_-_84104773 0.09 ENSMUST00000041367.7
DDB1 and CUL4 associated factor 15
chrX_+_134601271 0.09 ENSMUST00000050331.6
ENSMUST00000059297.5
heterogeneous nuclear ribonucleoprotein H2
chr16_+_43364145 0.09 ENSMUST00000148775.1
zinc finger and BTB domain containing 20
chrX_+_134601179 0.09 ENSMUST00000074950.4
ENSMUST00000113203.1
ENSMUST00000113202.1
heterogeneous nuclear ribonucleoprotein H2
chr13_+_37825975 0.09 ENSMUST00000138043.1
ras responsive element binding protein 1
chr9_-_37255403 0.09 ENSMUST00000161114.1
solute carrier family 37 (glycerol-3-phosphate transporter), member 2
chr5_+_53590453 0.09 ENSMUST00000113865.1
recombination signal binding protein for immunoglobulin kappa J region
chr5_+_21543525 0.09 ENSMUST00000035651.4
leucine rich repeat containing 17
chr2_-_119662756 0.09 ENSMUST00000028768.1
ENSMUST00000110801.1
ENSMUST00000110802.1
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 1
chr6_+_21986887 0.09 ENSMUST00000151315.1
cadherin-like and PC-esterase domain containing 1
chr11_+_70018728 0.09 ENSMUST00000018700.6
ENSMUST00000134376.2
discs, large homolog 4 (Drosophila)
chr12_+_37241729 0.09 ENSMUST00000160768.1
alkylglycerol monooxygenase
chr6_-_28831747 0.09 ENSMUST00000062304.5
leucine rich repeat containing 4
chr1_+_152807877 0.09 ENSMUST00000027754.6
neutrophil cytosolic factor 2
chr2_+_127909058 0.08 ENSMUST00000110344.1
acyl-Coenzyme A oxidase-like
chr1_-_106714217 0.08 ENSMUST00000112751.1
B cell leukemia/lymphoma 2
chr2_-_26964277 0.08 ENSMUST00000136710.1
ENSMUST00000064244.4
ENSMUST00000114020.3
REX4, RNA exonuclease 4 homolog (S. cerevisiae)
chr12_-_86079019 0.08 ENSMUST00000003687.6
transforming growth factor, beta 3
chr3_-_20275659 0.08 ENSMUST00000011607.5
carboxypeptidase B1 (tissue)
chr2_-_23155864 0.08 ENSMUST00000028119.6
microtubule associated serine/threonine kinase-like
chr11_-_99493112 0.08 ENSMUST00000006969.7
keratin 23
chr19_-_57360668 0.08 ENSMUST00000181921.1
RIKEN cDNA B230217O12 gene
chr2_-_62573905 0.08 ENSMUST00000102732.3
fibroblast activation protein
chr9_+_96258697 0.08 ENSMUST00000179416.1
transcription factor Dp 2
chr7_-_27181149 0.08 ENSMUST00000071986.6
ENSMUST00000121848.1
melanoma inhibitory activity
chr3_-_158562199 0.08 ENSMUST00000106044.1
leucine rich repeat containing 7
chr7_+_103979176 0.08 ENSMUST00000098185.1
olfactory receptor 635
chr7_-_127708886 0.08 ENSMUST00000061468.8
B cell CLL/lymphoma 7C
chr17_+_87975044 0.08 ENSMUST00000005503.3
mutS homolog 6 (E. coli)
chr18_-_35722330 0.08 ENSMUST00000133064.1
endothelial cell surface expressed chemotaxis and apoptosis regulator
chr14_-_55671873 0.08 ENSMUST00000163750.1
ENSMUST00000010520.8
neural precursor cell expressed, developmentally down-regulated gene 8
chr9_+_54951104 0.08 ENSMUST00000171900.1
proteasome (prosome, macropain) subunit, alpha type 4
chr11_+_96282529 0.08 ENSMUST00000125410.1
homeobox B8
chr3_-_152266320 0.08 ENSMUST00000046045.8
nexilin
chr10_+_107271827 0.08 ENSMUST00000020057.8
ENSMUST00000105280.3
lin-7 homolog A (C. elegans)
chr13_+_106947104 0.08 ENSMUST00000022203.8
DIM1 dimethyladenosine transferase 1-like (S. cerevisiae)
chr5_-_105343929 0.07 ENSMUST00000183149.1
guanylate binding protein 11
chr13_+_91461050 0.07 ENSMUST00000004094.8
ENSMUST00000042122.8
single-stranded DNA binding protein 2
chr11_-_3914664 0.07 ENSMUST00000109995.1
ENSMUST00000051207.1
solute carrier family 35, member E4
chr2_+_18677002 0.07 ENSMUST00000028071.6
Bmi1 polycomb ring finger oncogene
chr10_-_69212996 0.07 ENSMUST00000170048.1
RIKEN cDNA A930033H14 gene
chrX_+_112093496 0.07 ENSMUST00000130247.2
ENSMUST00000038546.6
testis expressed gene 16
chr13_-_99412816 0.07 ENSMUST00000180808.1
RIKEN cDNA 6430562O15 gene
chr10_-_34096507 0.07 ENSMUST00000069125.6
family with sequence similarity 26, member E
chr13_+_41655697 0.07 ENSMUST00000067176.8
predicted gene 5082
chr4_+_130047840 0.07 ENSMUST00000044565.8
ENSMUST00000132251.1
collagen, type XVI, alpha 1
chr2_+_155751117 0.07 ENSMUST00000029140.5
ENSMUST00000132608.1
protein C receptor, endothelial
chr1_+_153665274 0.07 ENSMUST00000152114.1
ENSMUST00000111812.1
regulator of G-protein signaling 8
chr7_+_110061702 0.07 ENSMUST00000084727.3
ENSMUST00000169638.2
zinc finger protein 143
chr18_+_4994600 0.07 ENSMUST00000140448.1
supervillin
chr6_-_136941694 0.07 ENSMUST00000032344.5
Rho, GDP dissociation inhibitor (GDI) beta
chr1_+_193301953 0.07 ENSMUST00000016315.9
laminin, beta 3
chr1_+_153652943 0.07 ENSMUST00000041776.5
regulator of G-protein signaling 8
chr10_+_25359798 0.07 ENSMUST00000053748.8
erythrocyte protein band 4.1-like 2
chr14_+_51884982 0.07 ENSMUST00000167984.1
methyltransferase like 17
chr18_-_4352944 0.07 ENSMUST00000025078.2
mitogen-activated protein kinase kinase kinase 8
chr3_+_84952146 0.07 ENSMUST00000029727.7
F-box and WD-40 domain protein 7
chr6_-_136875794 0.07 ENSMUST00000032342.1
matrix Gla protein
chr7_-_141655319 0.07 ENSMUST00000062451.7
mucin 6, gastric
chr4_-_11965699 0.07 ENSMUST00000108301.1
ENSMUST00000095144.3
ENSMUST00000108302.1
pyruvate dehyrogenase phosphatase catalytic subunit 1
chr7_-_99626936 0.07 ENSMUST00000178124.1
predicted gene 4980
chr10_+_90576872 0.07 ENSMUST00000182550.1
ENSMUST00000099364.5
ankyrin repeat and sterile alpha motif domain containing 1B

Network of associatons between targets according to the STRING database.

First level regulatory network of Nfatc3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.6 GO:0060523 Sertoli cell proliferation(GO:0060011) prostate epithelial cord elongation(GO:0060523)
0.2 0.6 GO:0045004 DNA replication proofreading(GO:0045004)
0.2 0.6 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
0.1 0.3 GO:0010716 regulation of collagen catabolic process(GO:0010710) negative regulation of extracellular matrix disassembly(GO:0010716)
0.1 0.7 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.1 0.3 GO:0033861 negative regulation of NAD(P)H oxidase activity(GO:0033861) regulation of complement-dependent cytotoxicity(GO:1903659) negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.1 0.4 GO:0006069 ethanol oxidation(GO:0006069)
0.1 0.1 GO:0002760 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) regulation of antimicrobial peptide production(GO:0002784) regulation of antibacterial peptide production(GO:0002786) positive regulation of antibacterial peptide production(GO:0002803)
0.1 0.3 GO:0052203 modulation by symbiont of host molecular function(GO:0052055) modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422)
0.1 0.3 GO:0032765 positive regulation of mast cell cytokine production(GO:0032765)
0.1 0.1 GO:0002780 antimicrobial peptide biosynthetic process(GO:0002777) antibacterial peptide biosynthetic process(GO:0002780)
0.1 0.2 GO:0090381 Notch signaling pathway involved in heart induction(GO:0003137) regulation of Notch signaling pathway involved in heart induction(GO:0035480) positive regulation of Notch signaling pathway involved in heart induction(GO:0035481) arterial endothelial cell fate commitment(GO:0060844) blood vessel endothelial cell fate commitment(GO:0060846) endothelial cell fate specification(GO:0060847) Notch signaling pathway involved in arterial endothelial cell fate commitment(GO:0060853) blood vessel lumenization(GO:0072554) regulation of heart induction(GO:0090381) blood vessel endothelial cell fate specification(GO:0097101) positive regulation of heart induction(GO:1901321)
0.1 0.2 GO:0036228 protein targeting to nuclear inner membrane(GO:0036228)
0.1 0.2 GO:0006127 glycerophosphate shuttle(GO:0006127)
0.1 0.3 GO:0060279 regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.1 0.3 GO:1904425 negative regulation of GTP binding(GO:1904425)
0.1 0.2 GO:0071608 macrophage inflammatory protein-1 alpha production(GO:0071608)
0.1 0.3 GO:0045578 negative regulation of B cell differentiation(GO:0045578)
0.0 0.2 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.0 0.1 GO:0010705 meiotic DNA double-strand break processing involved in reciprocal meiotic recombination(GO:0010705)
0.0 0.3 GO:0021730 trigeminal sensory nucleus development(GO:0021730) principal sensory nucleus of trigeminal nerve development(GO:0021740)
0.0 0.2 GO:0014734 skeletal muscle hypertrophy(GO:0014734)
0.0 0.5 GO:0009158 ribonucleoside monophosphate catabolic process(GO:0009158) purine ribonucleoside monophosphate catabolic process(GO:0009169)
0.0 0.1 GO:0046968 positive regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002591) peptide antigen transport(GO:0046968)
0.0 0.5 GO:0061303 cornea development in camera-type eye(GO:0061303)
0.0 0.1 GO:0070543 response to linoleic acid(GO:0070543)
0.0 0.2 GO:1904587 response to glycoprotein(GO:1904587)
0.0 0.1 GO:0003345 proepicardium cell migration involved in pericardium morphogenesis(GO:0003345)
0.0 0.1 GO:0021934 hindbrain tangential cell migration(GO:0021934)
0.0 0.2 GO:0007412 axon target recognition(GO:0007412)
0.0 0.1 GO:0090472 dibasic protein processing(GO:0090472)
0.0 0.1 GO:0015855 nucleobase transport(GO:0015851) pyrimidine nucleobase transport(GO:0015855)
0.0 0.1 GO:0033092 positive regulation of immature T cell proliferation in thymus(GO:0033092)
0.0 0.2 GO:0043137 DNA replication, removal of RNA primer(GO:0043137)
0.0 0.2 GO:0015862 uridine transport(GO:0015862)
0.0 0.1 GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302)
0.0 0.1 GO:2000321 positive regulation of T-helper 17 cell differentiation(GO:2000321)
0.0 0.1 GO:1903976 negative regulation of glial cell migration(GO:1903976)
0.0 0.3 GO:0072615 interleukin-17 secretion(GO:0072615)
0.0 0.1 GO:2000320 negative regulation of T-helper 17 type immune response(GO:2000317) negative regulation of T-helper 17 cell differentiation(GO:2000320)
0.0 0.2 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.0 0.1 GO:0046668 regulation of nitrogen utilization(GO:0006808) nitrogen utilization(GO:0019740) regulation of retinal cell programmed cell death(GO:0046668) positive regulation of skeletal muscle fiber development(GO:0048743)
0.0 0.1 GO:0003032 detection of oxygen(GO:0003032)
0.0 0.4 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.1 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.0 0.1 GO:0002436 immune complex clearance by monocytes and macrophages(GO:0002436) astrocyte chemotaxis(GO:0035700) regulation of immune complex clearance by monocytes and macrophages(GO:0090264) positive regulation of immune complex clearance by monocytes and macrophages(GO:0090265) negative regulation of eosinophil activation(GO:1902567) positive regulation of CD8-positive, alpha-beta T cell extravasation(GO:2000451) regulation of astrocyte chemotaxis(GO:2000458)
0.0 0.2 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.0 0.1 GO:1990868 response to chemokine(GO:1990868) cellular response to chemokine(GO:1990869)
0.0 0.1 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.0 0.2 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.0 0.1 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.0 0.3 GO:2000580 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 0.1 GO:0030091 protein repair(GO:0030091)
0.0 0.3 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.0 0.1 GO:0060849 regulation of transcription involved in lymphatic endothelial cell fate commitment(GO:0060849)
0.0 0.1 GO:0006113 fermentation(GO:0006113) lactate biosynthetic process from pyruvate(GO:0019244) glucose catabolic process to lactate(GO:0019659) glycolytic fermentation(GO:0019660) glucose catabolic process to lactate via pyruvate(GO:0019661)
0.0 0.1 GO:0034147 regulation of granuloma formation(GO:0002631) negative regulation of granuloma formation(GO:0002632) regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429) tolerance induction to lipopolysaccharide(GO:0072573)
0.0 0.1 GO:0006742 NADP catabolic process(GO:0006742)
0.0 0.1 GO:0002023 reduction of food intake in response to dietary excess(GO:0002023)
0.0 0.3 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.0 0.2 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.0 0.5 GO:0044342 type B pancreatic cell proliferation(GO:0044342)
0.0 0.1 GO:1904627 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.0 0.1 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 0.3 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.0 0.1 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.0 0.3 GO:0051451 myoblast migration(GO:0051451)
0.0 0.1 GO:0044330 canonical Wnt signaling pathway involved in positive regulation of wound healing(GO:0044330) lactic acid secretion(GO:0046722) regulation of metanephric cap mesenchymal cell proliferation(GO:0090095) positive regulation of metanephric cap mesenchymal cell proliferation(GO:0090096)
0.0 0.1 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.0 0.2 GO:0090026 positive regulation of monocyte chemotaxis(GO:0090026)
0.0 0.1 GO:0060591 chondroblast differentiation(GO:0060591)
0.0 0.1 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.0 0.0 GO:0071918 urea transmembrane transport(GO:0071918)
0.0 0.1 GO:0051096 positive regulation of helicase activity(GO:0051096)
0.0 0.2 GO:0006309 apoptotic DNA fragmentation(GO:0006309)
0.0 0.1 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.0 0.1 GO:2000402 negative regulation of lymphocyte migration(GO:2000402)
0.0 0.1 GO:0048539 bone marrow development(GO:0048539)
0.0 0.1 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560)
0.0 0.1 GO:0007213 G-protein coupled acetylcholine receptor signaling pathway(GO:0007213)
0.0 0.1 GO:1901837 negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901837)
0.0 0.0 GO:0030043 actin filament fragmentation(GO:0030043)
0.0 0.1 GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.0 0.1 GO:1901164 negative regulation of trophoblast cell migration(GO:1901164)
0.0 0.0 GO:0002669 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.6 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.1 0.6 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.1 0.3 GO:0043512 inhibin A complex(GO:0043512)
0.0 0.3 GO:0071438 invadopodium membrane(GO:0071438)
0.0 0.2 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.2 GO:0045160 myosin I complex(GO:0045160)
0.0 0.2 GO:0044611 nuclear pore inner ring(GO:0044611)
0.0 0.3 GO:0036194 muscle cell projection(GO:0036194) muscle cell projection membrane(GO:0036195)
0.0 0.2 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.0 0.6 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.1 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.1 GO:0005610 laminin-5 complex(GO:0005610)
0.0 0.1 GO:0072559 NLRP3 inflammasome complex(GO:0072559)
0.0 0.1 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.0 GO:0031417 NatC complex(GO:0031417)
0.0 0.2 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.1 GO:0042825 TAP complex(GO:0042825)
0.0 0.2 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.1 GO:0000801 central element(GO:0000801)
0.0 0.1 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
0.0 0.1 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.0 0.1 GO:0034709 methylosome(GO:0034709)
0.0 0.0 GO:0032021 NELF complex(GO:0032021)
0.0 0.2 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 0.2 GO:0035748 myelin sheath abaxonal region(GO:0035748)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798)
0.1 0.4 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.1 1.0 GO:0001849 complement component C1q binding(GO:0001849)
0.1 0.6 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.1 0.2 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.1 0.3 GO:0008142 oxysterol binding(GO:0008142)
0.1 0.2 GO:0015315 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.0 0.1 GO:0098770 FBXO family protein binding(GO:0098770)
0.0 0.3 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.0 0.1 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.0 0.3 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 0.2 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.0 0.3 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.0 0.2 GO:0004768 stearoyl-CoA 9-desaturase activity(GO:0004768)
0.0 0.2 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.1 GO:0070892 lipoteichoic acid receptor activity(GO:0070892)
0.0 0.1 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.0 0.1 GO:1902271 D3 vitamins binding(GO:1902271)
0.0 0.1 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.0 0.2 GO:0001537 N-acetylgalactosamine 4-O-sulfotransferase activity(GO:0001537)
0.0 0.2 GO:0015265 urea channel activity(GO:0015265)
0.0 0.3 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0 0.3 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.2 GO:0032027 myosin light chain binding(GO:0032027)
0.0 0.2 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0 0.1 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 0.1 GO:0035717 chemokine (C-C motif) ligand 7 binding(GO:0035717)
0.0 0.5 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.2 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.1 GO:0032137 guanine/thymine mispair binding(GO:0032137) single guanine insertion binding(GO:0032142)
0.0 0.1 GO:0008988 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179) rRNA (adenine-N6-)-methyltransferase activity(GO:0008988)
0.0 0.1 GO:0015433 peptide antigen-transporting ATPase activity(GO:0015433) tapasin binding(GO:0046980)
0.0 0.1 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
0.0 0.1 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0 0.1 GO:0019863 IgE binding(GO:0019863)
0.0 0.1 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.6 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.1 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.0 0.7 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.2 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.1 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.0 0.1 GO:0016649 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.0 0.1 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.0 0.1 GO:0003963 RNA-3'-phosphate cyclase activity(GO:0003963)
0.0 0.2 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.1 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.0 0.1 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.0 0.1 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.1 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.0 0.3 GO:0042923 neuropeptide binding(GO:0042923)
0.0 0.4 GO:0070410 co-SMAD binding(GO:0070410)
0.0 0.1 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.0 0.1 GO:0031404 chloride ion binding(GO:0031404)
0.0 0.1 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 0.1 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.0 0.0 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.0 0.1 GO:0097016 L27 domain binding(GO:0097016)
0.0 0.1 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.0 0.1 GO:0043426 MRF binding(GO:0043426)
0.0 0.2 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.1 GO:0031812 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.0 0.1 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.0 0.1 GO:0046972 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.1 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.1 0.3 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 1.6 PID FOXM1 PATHWAY FOXM1 transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.1 0.4 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.1 0.2 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.1 0.3 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.6 REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.0 0.4 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.5 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.3 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 1.8 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.1 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0 0.7 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.1 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 0.2 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.1 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.0 0.2 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.4 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0 0.4 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.1 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins