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2D miR_HR1_12

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Results for Gmeb1

Z-value: 0.29

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Transcription factors associated with Gmeb1

Gene Symbol Gene ID Gene Info
ENSMUSG00000028901.7 glucocorticoid modulatory element binding protein 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Gmeb1mm10_v2_chr4_-_132261521_1322615720.519.4e-02Click!

Activity profile of Gmeb1 motif

Sorted Z-values of Gmeb1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr6_+_113531675 0.42 ENSMUST00000036340.5
ENSMUST00000101051.2
Fanconi anemia, complementation group D2
chr11_-_40733373 0.39 ENSMUST00000020579.8
hyaluronan mediated motility receptor (RHAMM)
chr2_-_157007015 0.37 ENSMUST00000146413.1
DSN1, MIND kinetochore complex component, homolog (S. cerevisiae)
chr15_+_99074968 0.37 ENSMUST00000039665.6
trophinin associated protein
chr2_-_157007039 0.30 ENSMUST00000103129.2
ENSMUST00000103130.1
DSN1, MIND kinetochore complex component, homolog (S. cerevisiae)
chr3_+_40800054 0.30 ENSMUST00000168287.1
polo-like kinase 4
chr1_+_175880775 0.29 ENSMUST00000039725.6
exonuclease 1
chr8_-_123949201 0.28 ENSMUST00000044795.7
nucleoporin 133
chr3_+_40800013 0.25 ENSMUST00000026858.5
ENSMUST00000170825.1
polo-like kinase 4
chr3_+_127553462 0.20 ENSMUST00000043108.4
RIKEN cDNA 4930422G04 gene
chr15_-_58135047 0.18 ENSMUST00000038194.3
ATPase family, AAA domain containing 2
chr2_+_75659253 0.15 ENSMUST00000111964.1
ENSMUST00000111962.1
ENSMUST00000111961.1
ENSMUST00000164947.2
ENSMUST00000090792.4
heterogeneous nuclear ribonucleoprotein A3
chr17_+_84511832 0.14 ENSMUST00000047206.5
pleckstrin homology domain containing, family H (with MyTH4 domain) member 2
chr7_+_35397046 0.13 ENSMUST00000079414.5
centrosomal protein 89
chr19_-_40588374 0.13 ENSMUST00000175932.1
ENSMUST00000176955.1
ENSMUST00000149476.2
aldehyde dehydrogenase 18 family, member A1
chr19_-_44135816 0.11 ENSMUST00000026218.5
CWF19-like 1, cell cycle control (S. pombe)
chr8_+_26119611 0.11 ENSMUST00000140819.1
ring finger protein 170
chr11_-_6626030 0.11 ENSMUST00000000394.7
ENSMUST00000136682.1
transforming growth factor beta regulated gene 4
chr11_+_86544982 0.11 ENSMUST00000108030.2
ENSMUST00000020821.3
ENSMUST00000069503.6
ENSMUST00000167178.2
tubulin, delta 1
chr6_-_87672142 0.11 ENSMUST00000032130.2
ENSMUST00000065997.2
aprataxin and PNKP like factor
chrX_+_150588223 0.10 ENSMUST00000153221.1
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr19_-_40588338 0.09 ENSMUST00000176939.1
aldehyde dehydrogenase 18 family, member A1
chr19_-_40588453 0.09 ENSMUST00000025979.6
aldehyde dehydrogenase 18 family, member A1
chr4_-_40269778 0.09 ENSMUST00000042575.6
topoisomerase I binding, arginine/serine-rich
chr15_+_102073773 0.09 ENSMUST00000169681.1
eukaryotic translation initiation factor 4B
chr17_+_83350925 0.06 ENSMUST00000096766.4
ENSMUST00000112363.2
ENSMUST00000049503.8
echinoderm microtubule associated protein like 4
chr5_+_93206518 0.06 ENSMUST00000031330.4
RIKEN cDNA 2010109A12 gene
chr4_+_55350043 0.06 ENSMUST00000030134.8
RAD23b homolog (S. cerevisiae)
chr4_-_126202583 0.06 ENSMUST00000106142.1
ENSMUST00000169403.1
ENSMUST00000130334.1
thyroid hormone receptor associated protein 3
chr8_+_23139157 0.05 ENSMUST00000174435.1
ankyrin 1, erythroid
chr17_-_56626872 0.05 ENSMUST00000047226.8
lon peptidase 1, mitochondrial
chr10_-_81378459 0.05 ENSMUST00000140901.1
fizzy/cell division cycle 20 related 1 (Drosophila)
chr3_-_127553233 0.05 ENSMUST00000029588.5
La ribonucleoprotein domain family, member 7
chr4_+_88779850 0.05 ENSMUST00000179425.1
predicted gene 13272
chr12_-_31654767 0.04 ENSMUST00000020977.2
dihydrouridine synthase 4-like (S. cerevisiae)
chr11_-_97782377 0.04 ENSMUST00000128801.1
ribosomal protein L23
chr7_-_111082997 0.04 ENSMUST00000161051.1
ENSMUST00000160132.1
ENSMUST00000106666.3
ENSMUST00000162415.1
eukaryotic translation initiation factor 4, gamma 2
chr14_+_32085804 0.04 ENSMUST00000170600.1
ENSMUST00000168986.1
ENSMUST00000169649.1
oxidoreductase NAD-binding domain containing 1
chr7_+_101663705 0.04 ENSMUST00000106998.1
ClpB caseinolytic peptidase B
chr8_+_23139064 0.03 ENSMUST00000033947.8
ankyrin 1, erythroid
chr11_+_22990519 0.03 ENSMUST00000173867.1
ENSMUST00000020562.4
chaperonin containing Tcp1, subunit 4 (delta)
chr11_-_74724670 0.03 ENSMUST00000021091.8
platelet-activating factor acetylhydrolase, isoform 1b, subunit 1
chr19_+_46075842 0.03 ENSMUST00000165017.1
nucleolar and coiled-body phosphoprotein 1
chr8_-_45333189 0.03 ENSMUST00000095328.4
cytochrome P450, family 4, subfamily v, polypeptide 3
chr3_+_138143483 0.03 ENSMUST00000162864.1
tRNA methyltransferase 10A
chr5_-_93206428 0.03 ENSMUST00000144514.1
cyclin I
chr11_-_97782409 0.03 ENSMUST00000103146.4
ribosomal protein L23
chr11_-_86544754 0.03 ENSMUST00000138810.1
ENSMUST00000058286.2
ENSMUST00000154617.1
ribosomal protein S6 kinase, polypeptide 1
chr7_-_83884289 0.03 ENSMUST00000094216.3
mesoderm development candidate 1
chr19_-_41981119 0.03 ENSMUST00000026168.2
ENSMUST00000171561.1
MMS19 (MET18 S. cerevisiae)
chr6_-_128424883 0.03 ENSMUST00000001559.8
integrin alpha FG-GAP repeat containing 2
chr11_-_7213897 0.03 ENSMUST00000020702.4
ENSMUST00000135887.2
insulin-like growth factor binding protein 3
chr18_+_23954668 0.03 ENSMUST00000060762.4
zinc finger protein 397
chr7_+_101663633 0.02 ENSMUST00000001884.7
ClpB caseinolytic peptidase B
chr7_+_30321740 0.02 ENSMUST00000098585.3
RIKEN cDNA E130208F15 gene
chr11_-_113751309 0.02 ENSMUST00000106616.1
CDC42 effector protein (Rho GTPase binding) 4
chr1_-_160212864 0.02 ENSMUST00000014370.5
calcyclin binding protein
chr3_+_138143429 0.02 ENSMUST00000040321.6
tRNA methyltransferase 10A
chrX_-_7898864 0.02 ENSMUST00000154552.1
polyglutamine binding protein 1
chr11_-_53980296 0.02 ENSMUST00000076493.4
solute carrier family 22 (organic cation transporter), member 21
chr11_+_40733639 0.02 ENSMUST00000020578.4
NudC domain containing 2
chr4_+_128727585 0.02 ENSMUST00000106079.3
ENSMUST00000133439.1
polyhomeotic-like 2 (Drosophila)
chr11_-_83302586 0.01 ENSMUST00000176374.1
peroxisomal biogenesis factor 12
chr12_+_4917376 0.01 ENSMUST00000045664.5
ATPase family, AAA domain containing 2B
chr18_+_36559972 0.01 ENSMUST00000134146.1
ankyrin repeat and KH domain containing 1
chr11_+_69914179 0.01 ENSMUST00000057884.5
G protein pathway suppressor 2
chr11_+_97315716 0.01 ENSMUST00000019026.3
ENSMUST00000132168.1
mitochondrial ribosomal protein L45
chr5_-_93206489 0.01 ENSMUST00000058550.8
cyclin I
chr15_-_81399594 0.01 ENSMUST00000023039.8
suppression of tumorigenicity 13
chr19_-_7217549 0.01 ENSMUST00000039758.4
cytochrome c oxidase subunit VIIIa
chr4_-_126202757 0.01 ENSMUST00000080919.5
thyroid hormone receptor associated protein 3
chr8_-_25016901 0.01 ENSMUST00000084035.5
a disintegrin and metallopeptidase domain 9 (meltrin gamma)
chr4_-_72200833 0.01 ENSMUST00000102848.2
ENSMUST00000072695.6
ENSMUST00000107337.1
ENSMUST00000074216.7
transducin-like enhancer of split 1, homolog of Drosophila E(spl)
chr9_-_45906837 0.00 ENSMUST00000161203.1
ENSMUST00000058720.5
ENSMUST00000160699.1
ring finger protein 214
chr8_-_25016743 0.00 ENSMUST00000084032.5
a disintegrin and metallopeptidase domain 9 (meltrin gamma)
chr14_+_20694956 0.00 ENSMUST00000048016.1
fucosyltransferase 11
chr1_+_82316452 0.00 ENSMUST00000027322.7
rhomboid domain containing 1
chr4_-_135353126 0.00 ENSMUST00000030613.4
ENSMUST00000131373.1
serine/arginine repetitive matrix 1

Network of associatons between targets according to the STRING database.

First level regulatory network of Gmeb1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0051316 attachment of spindle microtubules to kinetochore involved in meiotic chromosome segregation(GO:0051316)
0.1 0.3 GO:0006592 ornithine biosynthetic process(GO:0006592)
0.1 0.5 GO:0098535 positive regulation of centriole replication(GO:0046601) de novo centriole assembly(GO:0098535)
0.0 0.4 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.0 0.3 GO:0000972 transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972)
0.0 0.3 GO:0016446 somatic hypermutation of immunoglobulin genes(GO:0016446)
0.0 0.1 GO:0000715 nucleotide-excision repair, DNA damage recognition(GO:0000715)
0.0 0.1 GO:0051106 regulation of DNA ligation(GO:0051105) positive regulation of DNA ligation(GO:0051106)
0.0 0.2 GO:0031936 negative regulation of chromatin silencing(GO:0031936)
0.0 0.1 GO:0072717 cellular response to actinomycin D(GO:0072717)
0.0 0.1 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0000818 nuclear MIS12/MIND complex(GO:0000818) condensed chromosome inner kinetochore(GO:0000939)
0.1 0.5 GO:0098536 deuterosome(GO:0098536)
0.0 0.1 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.0 0.3 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.1 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.1 GO:0071942 XPC complex(GO:0071942)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0019202 glutamate 5-kinase activity(GO:0004349) glutamate-5-semialdehyde dehydrogenase activity(GO:0004350) delta1-pyrroline-5-carboxylate synthetase activity(GO:0017084) amino acid kinase activity(GO:0019202)
0.1 0.3 GO:0008309 double-stranded DNA exodeoxyribonuclease activity(GO:0008309)
0.0 0.1 GO:0051033 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.0 0.4 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.5 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 0.0 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.0 0.1 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.0 0.1 GO:0070095 fructose-6-phosphate binding(GO:0070095)
0.0 0.1 GO:0033592 RNA strand annealing activity(GO:0033592)
0.0 0.3 GO:0017056 structural constituent of nuclear pore(GO:0017056)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 PID BARD1 PATHWAY BARD1 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.4 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.3 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)