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2D miR_HR1_12

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Results for Tbx5

Z-value: 1.30

Motif logo

Transcription factors associated with Tbx5

Gene Symbol Gene ID Gene Info
ENSMUSG00000018263.8 T-box 5

Activity profile of Tbx5 motif

Sorted Z-values of Tbx5 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr7_+_79810727 4.29 ENSMUST00000107394.1
mesoderm posterior 2
chr11_+_120530688 4.26 ENSMUST00000026119.7
glucagon receptor
chr2_-_144331695 2.51 ENSMUST00000103171.3
ovo-like 2 (Drosophila)
chr2_-_144332146 2.36 ENSMUST00000037423.3
ovo-like 2 (Drosophila)
chr1_+_74601441 2.02 ENSMUST00000087183.4
ENSMUST00000148456.1
ENSMUST00000113694.1
serine/threonine kinase 36
chr8_-_105933832 1.99 ENSMUST00000034368.6
chymotrypsin-like
chr2_+_70562147 1.95 ENSMUST00000148210.1
glutamate decarboxylase 1
chr7_-_4546567 1.95 ENSMUST00000065957.5
synaptotagmin V
chr7_-_79793788 1.88 ENSMUST00000032760.5
mesoderm posterior 1
chr1_+_74601548 1.81 ENSMUST00000087186.4
serine/threonine kinase 36
chr9_-_44320229 1.77 ENSMUST00000065080.8
C2 calcium-dependent domain containing 2-like
chr7_-_100658394 1.74 ENSMUST00000138830.1
ENSMUST00000107044.3
ENSMUST00000116287.2
pleckstrin homology domain containing, family B (evectins) member 1
chr11_+_69965396 1.57 ENSMUST00000018713.6
claudin 7
chr4_+_58943575 1.56 ENSMUST00000107554.1
zinc finger with KRAB and SCAN domains 16
chr7_-_100658364 1.54 ENSMUST00000107043.1
pleckstrin homology domain containing, family B (evectins) member 1
chr7_-_140082246 1.46 ENSMUST00000166758.2
calcyon neuron-specific vesicular protein
chr3_+_126596951 1.45 ENSMUST00000106402.1
calcium/calmodulin-dependent protein kinase II, delta
chr17_+_24488773 1.44 ENSMUST00000024958.7
CASK interacting protein 1
chr16_+_17276291 1.36 ENSMUST00000164950.1
ENSMUST00000159242.1
transmembrane protein 191C
chr3_+_126596993 1.35 ENSMUST00000163226.1
ENSMUST00000066466.6
ENSMUST00000169051.1
calcium/calmodulin-dependent protein kinase II, delta
chr16_+_17276337 1.30 ENSMUST00000159065.1
ENSMUST00000159494.1
ENSMUST00000159811.1
transmembrane protein 191C
chr6_+_30639218 1.26 ENSMUST00000031806.9
carboxypeptidase A1, pancreatic
chr4_-_43045686 1.25 ENSMUST00000107956.1
ENSMUST00000107957.1
family with sequence similarity 214, member B
chr9_+_107580746 1.23 ENSMUST00000148440.1
hyaluronoglucosaminidase 3
chr2_+_4919004 1.22 ENSMUST00000027975.7
phytanoyl-CoA hydroxylase
chr3_-_90465858 1.20 ENSMUST00000029540.6
natriuretic peptide receptor 1
chr3_+_126597299 1.19 ENSMUST00000106400.2
ENSMUST00000106401.1
calcium/calmodulin-dependent protein kinase II, delta
chrX_+_41401304 1.17 ENSMUST00000076349.5
glutamate receptor, ionotropic, AMPA3 (alpha 3)
chr1_+_72284367 1.14 ENSMUST00000027380.5
ENSMUST00000141783.1
transmembrane protein 169
chr11_+_98348404 1.12 ENSMUST00000078694.6
protein phosphatase 1, regulatory (inhibitor) subunit 1B
chr16_+_93683184 1.10 ENSMUST00000039620.6
carbonyl reductase 3
chr19_+_54045182 1.10 ENSMUST00000036700.5
adrenergic receptor, alpha 2a
chr8_+_76902277 1.10 ENSMUST00000109912.1
ENSMUST00000128862.1
ENSMUST00000109911.1
nuclear receptor subfamily 3, group C, member 2
chr11_+_96929260 1.09 ENSMUST00000054311.5
ENSMUST00000107636.3
proline rich 15-like
chr4_+_43046014 1.08 ENSMUST00000180426.1
predicted gene, 26881
chr2_+_24186469 1.07 ENSMUST00000057567.2
interleukin 1 family, member 9
chr3_+_132085281 1.07 ENSMUST00000029665.5
dickkopf homolog 2 (Xenopus laevis)
chr11_+_110399115 1.07 ENSMUST00000020949.5
ENSMUST00000100260.1
mitogen-activated protein kinase kinase 6
chr9_+_107581296 1.06 ENSMUST00000040059.2
hyaluronoglucosaminidase 3
chr11_+_69095217 1.06 ENSMUST00000101004.2
period circadian clock 1
chr19_+_6341121 1.03 ENSMUST00000025897.6
ENSMUST00000130382.1
mitogen-activated protein kinase kinase kinase kinase 2
chrX_+_134295225 1.01 ENSMUST00000037687.7
transmembrane protein 35
chr6_+_55336424 1.00 ENSMUST00000004774.3
aquaporin 1
chr11_+_96929367 1.00 ENSMUST00000062172.5
proline rich 15-like
chr3_-_20275659 0.99 ENSMUST00000011607.5
carboxypeptidase B1 (tissue)
chr9_-_62537036 0.99 ENSMUST00000048043.5
coronin, actin binding protein, 2B
chr4_-_140665891 0.97 ENSMUST00000069623.5
Rho guanine nucleotide exchange factor (GEF) 10-like
chr7_+_113513829 0.96 ENSMUST00000033018.8
fatty acyl CoA reductase 1
chr3_+_127789872 0.95 ENSMUST00000054483.7
ENSMUST00000163775.1
TRAF-interacting protein with forkhead-associated domain
chr5_-_22344690 0.92 ENSMUST00000062372.7
ENSMUST00000161356.1
reelin
chr6_-_126166726 0.91 ENSMUST00000112244.2
ENSMUST00000050484.7
neurotrophin 3
chr13_-_56296551 0.91 ENSMUST00000021970.9
chemokine (C-X-C motif) ligand 14
chr11_+_53519725 0.91 ENSMUST00000108987.1
ENSMUST00000121334.1
ENSMUST00000117061.1
septin 8
chr14_-_57104693 0.90 ENSMUST00000055698.7
gap junction protein, beta 2
chr11_+_66911981 0.90 ENSMUST00000123434.2
phosphoinositide-interacting regulator of transient receptor potential channels
chr1_+_88134786 0.89 ENSMUST00000113134.1
ENSMUST00000140092.1
UDP glucuronosyltransferase 1 family, polypeptide A6A
chr7_-_19749464 0.88 ENSMUST00000075447.7
ENSMUST00000108450.3
poliovirus receptor-related 2
chr5_-_100719675 0.87 ENSMUST00000112908.1
ENSMUST00000045617.8
heparanase
chr13_-_62888282 0.85 ENSMUST00000092888.4
fructose bisphosphatase 1
chr5_-_116591811 0.85 ENSMUST00000076124.5
serine/arginine repetitive matrix 4
chr6_-_52012476 0.85 ENSMUST00000078214.5
src family associated phosphoprotein 2
chr13_-_99900645 0.84 ENSMUST00000022150.6
CART prepropeptide
chr17_-_31144271 0.83 ENSMUST00000024826.7
trefoil factor 2 (spasmolytic protein 1)
chr17_+_21383725 0.82 ENSMUST00000056107.4
ENSMUST00000162659.1
zinc finger protein 677
chrX_-_155623325 0.81 ENSMUST00000038665.5
patched domain containing 1
chrX_+_159840463 0.80 ENSMUST00000112451.1
ENSMUST00000112453.2
SH3-domain kinase binding protein 1
chr10_+_93641041 0.80 ENSMUST00000020204.4
netrin 4
chr10_+_86705811 0.77 ENSMUST00000061458.7
ENSMUST00000075632.6
cDNA sequence BC030307
chr4_+_84884366 0.75 ENSMUST00000102819.3
centlein, centrosomal protein
chr2_+_103970221 0.75 ENSMUST00000111140.2
ENSMUST00000111139.2
LIM domain only 2
chr11_+_116280939 0.75 ENSMUST00000055872.2
galanin receptor 2
chr9_+_108953578 0.75 ENSMUST00000112070.1
collagen, type VII, alpha 1
chr8_-_47675556 0.75 ENSMUST00000125536.1
inhibitor of growth family, member 2
chr4_+_84884418 0.73 ENSMUST00000169371.2
centlein, centrosomal protein
chr11_+_78188737 0.73 ENSMUST00000108322.2
RAB34, member of RAS oncogene family
chr11_+_45980309 0.72 ENSMUST00000049038.3
SRY-box containing gene 30
chr1_+_188953744 0.71 ENSMUST00000127077.1
Usher syndrome 2A (autosomal recessive, mild)
chr8_+_13037308 0.71 ENSMUST00000063820.5
ENSMUST00000033821.4
coagulation factor X
chrX_-_7740206 0.71 ENSMUST00000128289.1
coiled-coil domain containing 120
chr17_-_6948283 0.70 ENSMUST00000024572.9
radial spoke 3B homolog (Chlamydomonas)
chr6_-_52191695 0.68 ENSMUST00000101395.2
homeobox A4
chr18_-_38209762 0.67 ENSMUST00000057185.6
protocadherin 1
chr9_+_108953597 0.67 ENSMUST00000026740.5
collagen, type VII, alpha 1
chr6_-_52208694 0.67 ENSMUST00000062829.7
homeobox A6
chr6_+_125049952 0.66 ENSMUST00000088294.5
ENSMUST00000032481.7
proacrosin binding protein
chr11_+_87582201 0.65 ENSMUST00000133202.1
septin 4
chrX_+_105120361 0.65 ENSMUST00000033578.5
melanoma antigen, family E, 1
chr9_-_96437434 0.65 ENSMUST00000070500.2
cDNA sequence BC043934
chr11_+_70700606 0.65 ENSMUST00000137119.2
kinesin family member 1C
chr10_-_81600857 0.65 ENSMUST00000151858.1
ENSMUST00000142948.1
ENSMUST00000072020.2
transducin-like enhancer of split 6, homolog of Drosophila E(spl)
chr19_-_6235804 0.65 ENSMUST00000025695.9
protein phosphatase 2, regulatory subunit B (B56), beta isoform
chrX_+_169036610 0.64 ENSMUST00000087016.4
ENSMUST00000112129.1
ENSMUST00000112131.2
Rho GTPase activating protein 6
chr8_+_125669818 0.64 ENSMUST00000053078.3
microtubule-associated protein 10
chrX_+_41401128 0.63 ENSMUST00000115103.2
glutamate receptor, ionotropic, AMPA3 (alpha 3)
chr6_-_113343975 0.62 ENSMUST00000155543.1
ENSMUST00000032409.8
calcium/calmodulin-dependent protein kinase I
chr15_+_16778101 0.62 ENSMUST00000026432.6
cadherin 9
chr7_-_19023538 0.62 ENSMUST00000036018.5
forkhead box A3
chr17_+_72836678 0.60 ENSMUST00000045174.5
yippee-like 5 (Drosophila)
chr7_-_27396542 0.60 ENSMUST00000108363.1
spectrin beta, non-erythrocytic 4
chr17_+_32506446 0.60 ENSMUST00000165999.1
cytochrome P450, family 4, subfamily f, polypeptide 17
chr7_+_141461728 0.60 ENSMUST00000167491.1
ENSMUST00000165194.1
EF-hand calcium binding domain 4A
chr9_+_88581036 0.59 ENSMUST00000164661.2
tripartite motif-containing 43A
chr9_+_75232013 0.58 ENSMUST00000036555.6
myosin VC
chr3_+_75557530 0.57 ENSMUST00000161776.1
ENSMUST00000029423.8
serine (or cysteine) peptidase inhibitor, clade I, member 1
chr2_-_38926217 0.57 ENSMUST00000076275.4
ENSMUST00000142130.1
nuclear receptor subfamily 6, group A, member 1
chr9_+_74848437 0.56 ENSMUST00000161862.1
ENSMUST00000162089.1
ENSMUST00000160017.1
ENSMUST00000160950.1
predicted gene 16551
predicted gene 20649
chr7_+_113513854 0.54 ENSMUST00000067929.8
ENSMUST00000129087.1
ENSMUST00000164745.1
ENSMUST00000136158.1
fatty acyl CoA reductase 1
chr17_+_46681038 0.54 ENSMUST00000002845.6
male enhanced antigen 1
chr3_+_90062781 0.54 ENSMUST00000029551.2
RIKEN cDNA 1700094D03 gene
chr7_-_44849075 0.53 ENSMUST00000047085.8
TBC1 domain family, member 17
chr6_+_54681687 0.53 ENSMUST00000046276.6
RIKEN cDNA 2410066E13 gene
chr14_-_66009204 0.53 ENSMUST00000059970.7
gulonolactone (L-) oxidase
chr4_+_84884276 0.53 ENSMUST00000047023.6
centlein, centrosomal protein
chr14_+_65266701 0.52 ENSMUST00000169656.1
F-box protein 16
chr6_+_48395586 0.52 ENSMUST00000114571.1
ENSMUST00000114572.3
ENSMUST00000031815.5
KRAB-A domain containing 1
chr11_+_70700473 0.51 ENSMUST00000152618.2
ENSMUST00000102554.1
ENSMUST00000094499.4
ENSMUST00000072187.5
kinesin family member 1C
chr3_-_89402650 0.51 ENSMUST00000168325.1
ENSMUST00000057431.5
lens epithelial protein
chr11_+_72961163 0.51 ENSMUST00000108486.1
ENSMUST00000108484.1
ENSMUST00000021142.7
ENSMUST00000108485.2
ENSMUST00000163326.1
ATPase, Ca++ transporting, ubiquitous
chr4_-_41517326 0.51 ENSMUST00000030152.6
ENSMUST00000095126.4
RIKEN cDNA 1110017D15 gene
chr15_-_89425795 0.51 ENSMUST00000168376.1
carnitine palmitoyltransferase 1b, muscle
chr7_+_44748584 0.51 ENSMUST00000171821.1
vaccinia related kinase 3
chrX_-_59134421 0.50 ENSMUST00000033473.5
fibroblast growth factor 13
chr3_+_51483966 0.50 ENSMUST00000054387.6
RAB33B, member of RAS oncogene family
chr9_+_107547288 0.50 ENSMUST00000010188.7
zinc finger, MYND domain containing 10
chr7_+_44496588 0.50 ENSMUST00000107927.3
family with sequence similarity 71, member E1
chr11_+_85832551 0.49 ENSMUST00000000095.6
T-box 2
chr9_-_106199253 0.49 ENSMUST00000140761.1
protein phosphatase 1M
chr2_+_32608704 0.49 ENSMUST00000129165.1
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
chr7_-_24316590 0.49 ENSMUST00000108436.1
ENSMUST00000032673.8
zinc finger protein 94
chr11_-_96943945 0.48 ENSMUST00000107629.1
ENSMUST00000018803.5
pyridoxine 5'-phosphate oxidase
chr1_+_135324770 0.48 ENSMUST00000059352.2
leiomodin 1 (smooth muscle)
chr6_-_125380793 0.47 ENSMUST00000042647.6
pleckstrin homology domain containing, family G (with RhoGef domain) member 6
chr9_+_107400043 0.47 ENSMUST00000166799.1
ENSMUST00000170737.1
calcium channel, voltage-dependent, alpha 2/delta subunit 2
chr7_+_25301343 0.47 ENSMUST00000080288.3
proline rich 19
chr13_-_38036923 0.46 ENSMUST00000110233.1
ENSMUST00000074969.4
ENSMUST00000131066.1
cancer antigen 1
chr15_-_73707387 0.45 ENSMUST00000064166.4
G protein-coupled receptor 20
chr2_-_121806988 0.45 ENSMUST00000110592.1
FERM domain containing 5
chr1_+_93373874 0.45 ENSMUST00000058682.4
anoctamin 7
chr8_-_85119637 0.44 ENSMUST00000098550.3
zinc finger protein 791
chr7_-_141117772 0.44 ENSMUST00000067836.7
anoctamin 9
chr6_+_48395652 0.44 ENSMUST00000077093.4
KRAB-A domain containing 1
chr11_-_70220794 0.43 ENSMUST00000159867.1
solute carrier family 16 (monocarboxylic acid transporters), member 13
chr5_-_24329556 0.43 ENSMUST00000115098.2
potassium voltage-gated channel, subfamily H (eag-related), member 2
chr12_-_111377705 0.42 ENSMUST00000041965.3
CDC42 binding protein kinase beta
chr10_-_127751707 0.42 ENSMUST00000079692.5
G protein-coupled receptor 182
chr7_-_28379247 0.41 ENSMUST00000051241.5
zinc finger protein 36
chrX_+_20364481 0.41 ENSMUST00000033372.6
ENSMUST00000115391.1
ENSMUST00000115387.1
retinitis pigmentosa 2 homolog (human)
chr6_+_108828633 0.41 ENSMUST00000089162.3
ER degradation enhancer, mannosidase alpha-like 1
chr9_+_108991902 0.41 ENSMUST00000147989.1
ENSMUST00000051873.8
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
chr12_-_84773087 0.40 ENSMUST00000021668.8
Niemann Pick type C2
chr15_-_78803015 0.40 ENSMUST00000164826.1
caspase recruitment domain family, member 10
chr15_-_97767244 0.40 ENSMUST00000146620.1
Rap guanine nucleotide exchange factor (GEF) 3
chr18_+_61555308 0.39 ENSMUST00000165721.1
ENSMUST00000115246.2
ENSMUST00000166990.1
ENSMUST00000163205.1
ENSMUST00000170862.1
casein kinase 1, alpha 1
chr15_-_101869695 0.39 ENSMUST00000087996.5
keratin 77
chr14_+_55765956 0.39 ENSMUST00000057569.3
leukotriene B4 receptor 1
chr18_+_61555258 0.39 ENSMUST00000165123.1
casein kinase 1, alpha 1
chr3_+_130180882 0.39 ENSMUST00000106353.1
ENSMUST00000080335.4
collagen, type XXV, alpha 1
chr16_+_41532999 0.38 ENSMUST00000099761.3
limbic system-associated membrane protein
chr11_-_70220776 0.38 ENSMUST00000141290.1
solute carrier family 16 (monocarboxylic acid transporters), member 13
chr9_-_43239816 0.38 ENSMUST00000034512.5
OAF homolog (Drosophila)
chr15_-_89425856 0.38 ENSMUST00000109313.2
carnitine palmitoyltransferase 1b, muscle
chr11_-_84068766 0.38 ENSMUST00000018792.5
dual specificity phosphatase 14
chr6_-_91807424 0.38 ENSMUST00000162300.1
glutamate receptor interacting protein 2
chr11_+_95712673 0.37 ENSMUST00000107717.1
zinc finger protein 652
chrX_-_51205990 0.37 ENSMUST00000114876.2
muscleblind-like 3 (Drosophila)
chr5_+_17574726 0.37 ENSMUST00000169603.1
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C
chr4_-_133602168 0.37 ENSMUST00000057311.3
stratifin
chr7_-_19861299 0.36 ENSMUST00000014830.7
carcinoembryonic antigen-related cell adhesion molecule 16
chr1_-_156718894 0.36 ENSMUST00000086153.6
family with sequence similarity 20, member B
chr5_-_139819906 0.36 ENSMUST00000147328.1
transmembrane protein 184a
chr1_-_74601345 0.36 ENSMUST00000136078.1
ENSMUST00000132081.1
ENSMUST00000113721.1
ENSMUST00000027357.5
ring finger protein 25
chr1_+_132417409 0.35 ENSMUST00000045110.7
dual serine/threonine and tyrosine protein kinase
chr1_+_86045863 0.35 ENSMUST00000165824.1
RIKEN cDNA 2810459M11 gene
chr4_-_151108244 0.35 ENSMUST00000131948.1
calmodulin binding transcription activator 1
chr11_+_98383811 0.35 ENSMUST00000008021.2
titin-cap
chr10_-_128821576 0.35 ENSMUST00000026409.3
ORM1-like 2 (S. cerevisiae)
chr2_+_11642786 0.35 ENSMUST00000028111.4
interleukin 2 receptor, alpha chain
chr15_+_98634743 0.35 ENSMUST00000003442.7
calcium channel, voltage-dependent, beta 3 subunit
chr11_+_83852920 0.35 ENSMUST00000108113.1
HNF1 homeobox B
chr1_-_133921393 0.34 ENSMUST00000048432.5
proline arginine-rich end leucine-rich repeat
chr7_-_113369326 0.34 ENSMUST00000047091.7
ENSMUST00000119278.1
BTB (POZ) domain containing 10
chr11_+_78188422 0.33 ENSMUST00000002128.7
ENSMUST00000150941.1
RAB34, member of RAS oncogene family
chr17_+_47505073 0.33 ENSMUST00000183210.1
cyclin D3
chr9_-_95845215 0.33 ENSMUST00000093800.2
plastin 1 (I-isoform)
chr12_+_113014502 0.33 ENSMUST00000084891.4
phosphofurin acidic cluster sorting protein 2
chr10_-_29535857 0.32 ENSMUST00000092623.3
R-spondin 3 homolog (Xenopus laevis)
chr2_+_6322621 0.32 ENSMUST00000114937.1
USP6 N-terminal like
chr9_-_35558522 0.32 ENSMUST00000034612.5
DEAD (Asp-Glu-Ala-Asp) box polypeptide 25
chr17_-_64331817 0.32 ENSMUST00000172733.1
ENSMUST00000172818.1
praja 2, RING-H2 motif containing
chr5_-_145879857 0.32 ENSMUST00000035918.7
cytochrome P450, family 3, subfamily a, polypeptide 11
chr19_-_28963863 0.32 ENSMUST00000161813.1
RIKEN cDNA 4430402I18 gene
chr11_-_95076657 0.32 ENSMUST00000001548.7
integrin alpha 3
chr14_+_80000292 0.31 ENSMUST00000088735.3
olfactomedin 4
chr15_-_78468620 0.31 ENSMUST00000017086.3
transmembrane serine protease 6
chr11_-_72795801 0.30 ENSMUST00000079681.5
cytochrome b5 domain containing 2
chr15_+_76331288 0.30 ENSMUST00000172281.1
GPI anchor attachment protein 1
chr6_-_52158292 0.30 ENSMUST00000000964.5
ENSMUST00000120363.1
homeobox A1
chr7_+_44748640 0.30 ENSMUST00000165957.1
ENSMUST00000144515.2
vaccinia related kinase 3
chr2_+_27079371 0.30 ENSMUST00000091233.6
ADAMTS-like 2
chr6_-_56901870 0.30 ENSMUST00000101367.2
5'-nucleotidase, cytosolic III

Network of associatons between targets according to the STRING database.

First level regulatory network of Tbx5

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 6.2 GO:0008078 mesodermal cell migration(GO:0008078)
1.0 3.8 GO:0007228 positive regulation of hh target transcription factor activity(GO:0007228)
0.7 4.3 GO:0033762 response to glucagon(GO:0033762)
0.7 4.0 GO:0035022 positive regulation of Rac protein signal transduction(GO:0035022)
0.6 4.9 GO:0060214 endocardium formation(GO:0060214)
0.4 1.2 GO:0097089 methyl-branched fatty acid metabolic process(GO:0097089)
0.4 1.1 GO:1901662 phylloquinone metabolic process(GO:0042374) phylloquinone catabolic process(GO:0042376) quinone catabolic process(GO:1901662)
0.4 1.1 GO:0031959 mineralocorticoid receptor signaling pathway(GO:0031959)
0.3 1.0 GO:0035377 transepithelial water transport(GO:0035377)
0.3 2.3 GO:0030214 hyaluronan catabolic process(GO:0030214)
0.3 0.9 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.3 1.2 GO:0097477 lateral motor column neuron migration(GO:0097477)
0.3 1.1 GO:0005984 disaccharide metabolic process(GO:0005984)
0.3 1.1 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.3 0.8 GO:0070093 negative regulation of glucagon secretion(GO:0070093)
0.3 2.0 GO:0009449 gamma-aminobutyric acid biosynthetic process(GO:0009449)
0.3 1.1 GO:1901740 negative regulation of myoblast fusion(GO:1901740)
0.3 1.5 GO:0010025 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.2 1.1 GO:1905171 protein localization to phagocytic vesicle(GO:1905161) regulation of protein localization to phagocytic vesicle(GO:1905169) positive regulation of protein localization to phagocytic vesicle(GO:1905171)
0.2 1.1 GO:0097167 circadian regulation of translation(GO:0097167)
0.2 0.6 GO:0070368 positive regulation of hepatocyte differentiation(GO:0070368)
0.2 1.1 GO:0035625 receptor transactivation(GO:0035624) epidermal growth factor-activated receptor transactivation by G-protein coupled receptor signaling pathway(GO:0035625)
0.2 0.9 GO:0007403 glial cell fate determination(GO:0007403)
0.2 0.9 GO:0061589 calcium activated phosphatidylserine scrambling(GO:0061589)
0.2 0.5 GO:0007521 muscle cell fate determination(GO:0007521)
0.2 0.5 GO:0042823 pyridoxal phosphate biosynthetic process(GO:0042823)
0.2 0.8 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.2 0.8 GO:1902606 regulation of large conductance calcium-activated potassium channel activity(GO:1902606) positive regulation of large conductance calcium-activated potassium channel activity(GO:1902608)
0.1 2.0 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.1 0.7 GO:0048496 maintenance of organ identity(GO:0048496)
0.1 0.8 GO:0060455 negative regulation of gastric acid secretion(GO:0060455)
0.1 0.4 GO:1904580 regulation of polynucleotide adenylyltransferase activity(GO:1904245) regulation of intracellular mRNA localization(GO:1904580)
0.1 0.4 GO:1904154 positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
0.1 0.5 GO:0019853 L-ascorbic acid biosynthetic process(GO:0019853)
0.1 0.5 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
0.1 0.7 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.1 0.3 GO:0030241 skeletal muscle myosin thick filament assembly(GO:0030241) detection of muscle stretch(GO:0035995)
0.1 0.3 GO:1900060 negative regulation of ceramide biosynthetic process(GO:1900060)
0.1 0.3 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.1 0.4 GO:1902303 negative regulation of potassium ion export(GO:1902303)
0.1 0.4 GO:0045054 constitutive secretory pathway(GO:0045054)
0.1 0.4 GO:1904453 regulation of hydrogen:potassium-exchanging ATPase activity(GO:1904451) positive regulation of hydrogen:potassium-exchanging ATPase activity(GO:1904453)
0.1 0.3 GO:2000860 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.1 0.7 GO:0030382 sperm mitochondrion organization(GO:0030382)
0.1 0.3 GO:2000040 regulation of planar cell polarity pathway involved in axis elongation(GO:2000040) negative regulation of planar cell polarity pathway involved in axis elongation(GO:2000041)
0.1 0.3 GO:2000224 regulation of testosterone biosynthetic process(GO:2000224)
0.1 1.0 GO:1904424 regulation of GTP binding(GO:1904424)
0.1 1.1 GO:0032308 positive regulation of prostaglandin secretion(GO:0032308)
0.1 0.6 GO:0051835 positive regulation of synapse structural plasticity(GO:0051835)
0.1 1.0 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.1 0.3 GO:0061228 regulation of pronephros size(GO:0035565) mesonephros morphogenesis(GO:0061206) mesonephric nephron development(GO:0061215) mesonephric nephron morphogenesis(GO:0061228) mesenchymal stem cell maintenance involved in mesonephric nephron morphogenesis(GO:0061235) regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:0061295) negative regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:0061296) mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:1901146)
0.1 0.3 GO:0060466 inhibitory G-protein coupled receptor phosphorylation(GO:0002030) activation of meiosis involved in egg activation(GO:0060466)
0.1 1.6 GO:0032463 negative regulation of protein homooligomerization(GO:0032463)
0.1 0.3 GO:1902896 terminal web assembly(GO:1902896)
0.1 0.6 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
0.1 0.5 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.1 0.6 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.1 1.2 GO:0030828 positive regulation of cGMP biosynthetic process(GO:0030828)
0.1 0.9 GO:0052697 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.1 0.4 GO:0003350 pulmonary myocardium development(GO:0003350)
0.1 0.5 GO:0045200 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200) regulation of cardiac muscle cell action potential involved in regulation of contraction(GO:0098909)
0.1 0.2 GO:0003127 detection of nodal flow(GO:0003127) detection of endogenous stimulus(GO:0009726)
0.1 0.5 GO:0060024 rhythmic synaptic transmission(GO:0060024)
0.1 0.2 GO:0071544 diphosphoinositol polyphosphate catabolic process(GO:0071544)
0.1 0.4 GO:0060385 axonogenesis involved in innervation(GO:0060385)
0.1 0.4 GO:0018992 germ-line sex determination(GO:0018992)
0.1 0.4 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.1 0.2 GO:0040010 positive regulation of growth rate(GO:0040010)
0.1 0.2 GO:1900248 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
0.1 1.0 GO:0032516 positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.1 1.5 GO:0048268 clathrin coat assembly(GO:0048268)
0.1 0.6 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.1 0.3 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.1 0.3 GO:0021571 rhombomere 5 development(GO:0021571)
0.0 0.6 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.0 0.2 GO:0033364 mast cell secretory granule organization(GO:0033364)
0.0 0.3 GO:1904491 protein localization to ciliary transition zone(GO:1904491)
0.0 0.0 GO:1902941 regulation of voltage-gated chloride channel activity(GO:1902941) positive regulation of voltage-gated chloride channel activity(GO:1902943)
0.0 0.4 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.5 GO:0014824 artery smooth muscle contraction(GO:0014824)
0.0 0.1 GO:0002786 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) regulation of antimicrobial peptide production(GO:0002784) regulation of antibacterial peptide production(GO:0002786) positive regulation of antibacterial peptide production(GO:0002803)
0.0 1.0 GO:0006903 vesicle targeting(GO:0006903)
0.0 1.0 GO:0006991 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.0 1.8 GO:0001919 regulation of receptor recycling(GO:0001919)
0.0 0.2 GO:0032485 regulation of Ral protein signal transduction(GO:0032485)
0.0 0.5 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.1 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.0 0.8 GO:0021794 thalamus development(GO:0021794)
0.0 0.2 GO:0007343 egg activation(GO:0007343)
0.0 1.9 GO:0048488 synaptic vesicle endocytosis(GO:0048488)
0.0 0.3 GO:1904378 maintenance of unfolded protein(GO:0036506) tail-anchored membrane protein insertion into ER membrane(GO:0071816) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.0 1.8 GO:0035774 positive regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0035774)
0.0 0.2 GO:0045900 negative regulation of translational elongation(GO:0045900)
0.0 0.2 GO:0097343 ripoptosome assembly(GO:0097343) ripoptosome assembly involved in necroptotic process(GO:1901026)
0.0 0.6 GO:0016264 gap junction assembly(GO:0016264)
0.0 0.2 GO:0015015 protein sulfation(GO:0006477) heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.0 0.9 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.2 GO:0001575 globoside metabolic process(GO:0001575)
0.0 0.5 GO:0036159 outer dynein arm assembly(GO:0036158) inner dynein arm assembly(GO:0036159)
0.0 0.1 GO:0009730 detection of carbohydrate stimulus(GO:0009730) detection of hexose stimulus(GO:0009732) detection of monosaccharide stimulus(GO:0034287) detection of glucose(GO:0051594)
0.0 0.4 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.0 1.3 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.6 GO:0032252 secretory granule localization(GO:0032252)
0.0 0.4 GO:0071361 cellular response to ethanol(GO:0071361)
0.0 0.2 GO:0030886 negative regulation of myeloid dendritic cell activation(GO:0030886)
0.0 0.6 GO:0007202 activation of phospholipase C activity(GO:0007202)
0.0 0.9 GO:0048266 behavioral response to pain(GO:0048266)
0.0 0.4 GO:0032366 intracellular sterol transport(GO:0032366) intracellular cholesterol transport(GO:0032367)
0.0 0.1 GO:1903031 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.0 0.2 GO:0002826 negative regulation of T-helper 1 type immune response(GO:0002826)
0.0 0.3 GO:0097264 self proteolysis(GO:0097264)
0.0 0.3 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.0 0.5 GO:0048240 sperm capacitation(GO:0048240)
0.0 0.3 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.7 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.0 0.2 GO:0035095 behavioral response to nicotine(GO:0035095)
0.0 0.4 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 0.6 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.0 0.4 GO:0071545 inositol phosphate catabolic process(GO:0071545)
0.0 0.3 GO:0060481 lobar bronchus epithelium development(GO:0060481)
0.0 0.3 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.0 0.6 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.1 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.0 0.1 GO:0034154 toll-like receptor 7 signaling pathway(GO:0034154)
0.0 0.3 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.0 0.2 GO:0007288 sperm axoneme assembly(GO:0007288)
0.0 0.2 GO:0071318 cellular response to ATP(GO:0071318)
0.0 0.3 GO:0032897 negative regulation of viral transcription(GO:0032897)
0.0 0.2 GO:0014051 gamma-aminobutyric acid secretion(GO:0014051) gamma-aminobutyric acid transport(GO:0015812)
0.0 0.2 GO:0042119 neutrophil activation(GO:0042119)
0.0 0.3 GO:0044342 type B pancreatic cell proliferation(GO:0044342)
0.0 0.3 GO:0006691 leukotriene metabolic process(GO:0006691)
0.0 0.2 GO:0007271 synaptic transmission, cholinergic(GO:0007271)
0.0 0.3 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.0 0.3 GO:0060009 Sertoli cell development(GO:0060009)
0.0 0.3 GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
0.0 0.1 GO:1900113 regulation of histone H3-K9 trimethylation(GO:1900112) negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.0 0.4 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.3 GO:0010738 regulation of protein kinase A signaling(GO:0010738)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.8 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.4 1.9 GO:1990769 proximal neuron projection(GO:1990769)
0.3 1.0 GO:0032127 dense core granule membrane(GO:0032127)
0.2 0.6 GO:0060205 secretory granule lumen(GO:0034774) cytoplasmic membrane-bounded vesicle lumen(GO:0060205)
0.2 0.6 GO:0034667 integrin alpha3-beta1 complex(GO:0034667)
0.2 0.7 GO:1990696 USH2 complex(GO:1990696)
0.1 1.8 GO:0043083 synaptic cleft(GO:0043083)
0.1 4.6 GO:0043194 axon initial segment(GO:0043194)
0.1 0.7 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.1 0.4 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.1 0.4 GO:0097574 lateral part of cell(GO:0097574) basolateral part of cell(GO:1990794) rod bipolar cell terminal bouton(GO:1990795)
0.1 0.3 GO:0035339 SPOTS complex(GO:0035339)
0.1 0.7 GO:0002177 manchette(GO:0002177)
0.1 0.5 GO:0005796 Golgi lumen(GO:0005796)
0.1 1.0 GO:0030877 beta-catenin destruction complex(GO:0030877)
0.1 0.9 GO:0097449 astrocyte projection(GO:0097449)
0.1 1.6 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 0.3 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.1 2.0 GO:0060077 inhibitory synapse(GO:0060077)
0.0 1.2 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 1.5 GO:0005779 integral component of peroxisomal membrane(GO:0005779)
0.0 0.3 GO:1990357 terminal web(GO:1990357)
0.0 0.4 GO:0070578 RISC-loading complex(GO:0070578)
0.0 0.2 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 0.3 GO:0072379 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0 0.9 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.4 GO:0097227 sperm annulus(GO:0097227)
0.0 0.3 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.1 GO:1990590 ATF1-ATF4 transcription factor complex(GO:1990590)
0.0 3.2 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.7 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.6 GO:0097431 mitotic spindle pole(GO:0097431)
0.0 0.4 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.0 0.6 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.3 GO:0042581 specific granule(GO:0042581)
0.0 0.2 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.4 GO:0032426 stereocilium tip(GO:0032426)
0.0 0.5 GO:0034451 centriolar satellite(GO:0034451)
0.0 1.8 GO:0005581 collagen trimer(GO:0005581)
0.0 0.3 GO:0033391 chromatoid body(GO:0033391)
0.0 0.4 GO:0045095 keratin filament(GO:0045095)
0.0 1.1 GO:0045335 phagocytic vesicle(GO:0045335)
0.0 0.7 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.2 GO:0097542 ciliary tip(GO:0097542)
0.0 0.2 GO:0034704 calcium channel complex(GO:0034704)
0.0 1.7 GO:0005814 centriole(GO:0005814)
0.0 0.2 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.4 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.5 GO:0005865 striated muscle thin filament(GO:0005865)
0.0 0.2 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.1 GO:0014731 spectrin-associated cytoskeleton(GO:0014731)
0.0 0.1 GO:0000242 pericentriolar material(GO:0000242)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 4.3 GO:0004967 glucagon receptor activity(GO:0004967)
0.8 2.3 GO:0033906 hyaluronoglucuronidase activity(GO:0033906)
0.4 4.0 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.4 1.1 GO:0031750 D3 dopamine receptor binding(GO:0031750) D5 dopamine receptor binding(GO:0031752)
0.4 1.1 GO:0000253 3-keto sterol reductase activity(GO:0000253)
0.4 1.1 GO:0051380 norepinephrine binding(GO:0051380)
0.4 1.1 GO:0017082 mineralocorticoid receptor activity(GO:0017082)
0.3 1.5 GO:0080019 fatty-acyl-CoA reductase (alcohol-forming) activity(GO:0080019)
0.3 2.0 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.3 1.8 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.2 1.2 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.2 1.8 GO:0043559 insulin binding(GO:0043559)
0.2 0.8 GO:0004966 galanin receptor activity(GO:0004966)
0.2 0.9 GO:0070326 very-low-density lipoprotein particle receptor binding(GO:0070326)
0.2 1.5 GO:0032051 clathrin light chain binding(GO:0032051)
0.2 0.9 GO:0016416 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.2 1.0 GO:0015168 glycerol transmembrane transporter activity(GO:0015168)
0.1 1.1 GO:0039706 co-receptor binding(GO:0039706)
0.1 0.4 GO:0004974 leukotriene receptor activity(GO:0004974)
0.1 0.9 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.1 0.3 GO:0004911 interleukin-2 receptor activity(GO:0004911)
0.1 0.9 GO:0045545 syndecan binding(GO:0045545)
0.1 0.8 GO:0043237 laminin-1 binding(GO:0043237)
0.1 0.4 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.1 1.3 GO:0050308 sugar-phosphatase activity(GO:0050308)
0.1 0.3 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.1 2.3 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 0.3 GO:0050436 microfibril binding(GO:0050436)
0.1 0.2 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.1 0.4 GO:0000155 phosphorelay sensor kinase activity(GO:0000155) voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282)
0.1 0.8 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.1 1.2 GO:0031418 L-ascorbic acid binding(GO:0031418)
0.1 0.3 GO:0034235 GPI anchor binding(GO:0034235)
0.1 0.2 GO:0003680 AT DNA binding(GO:0003680)
0.1 1.1 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.1 0.8 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.1 0.5 GO:0008420 CTD phosphatase activity(GO:0008420)
0.1 0.5 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.1 0.8 GO:0005243 gap junction channel activity(GO:0005243)
0.1 1.1 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.4 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.3 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.0 0.4 GO:0097642 calcitonin family receptor activity(GO:0097642)
0.0 0.6 GO:0060229 phospholipase activator activity(GO:0016004) lipase activator activity(GO:0060229)
0.0 0.4 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 1.1 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.2 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 0.5 GO:0005523 tropomyosin binding(GO:0005523)
0.0 2.1 GO:0070888 E-box binding(GO:0070888)
0.0 1.1 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.2 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.0 0.7 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.2 GO:0008486 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.0 0.9 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.5 GO:0010181 FMN binding(GO:0010181)
0.0 0.4 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439)
0.0 0.5 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.2 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.3 GO:0031432 titin binding(GO:0031432)
0.0 0.2 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.0 0.2 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.0 0.4 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.2 GO:1990380 Lys63-specific deubiquitinase activity(GO:0061578) Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.6 GO:0008009 chemokine activity(GO:0008009)
0.0 0.9 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.2 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 1.9 GO:0005518 collagen binding(GO:0005518)
0.0 2.5 GO:1902936 phosphatidylinositol bisphosphate binding(GO:1902936)
0.0 0.6 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.4 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.3 GO:0070330 aromatase activity(GO:0070330)
0.0 11.1 GO:0001228 transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001228)
0.0 0.3 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 0.1 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.2 GO:0046790 virion binding(GO:0046790)
0.0 0.4 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.2 GO:0042166 acetylcholine binding(GO:0042166)
0.0 0.2 GO:0034711 inhibin binding(GO:0034711)
0.0 0.1 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.3 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.2 GO:0015245 fatty acid transporter activity(GO:0015245)
0.0 0.5 GO:0005245 voltage-gated calcium channel activity(GO:0005245)
0.0 1.8 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.1 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.1 GO:0004875 complement receptor activity(GO:0004875)
0.0 0.5 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.5 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 0.2 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.3 GO:0042813 Wnt-activated receptor activity(GO:0042813)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.6 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.1 1.1 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.1 4.6 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.1 1.1 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 2.2 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 0.4 PID ERBB1 DOWNSTREAM PATHWAY ErbB1 downstream signaling
0.0 1.3 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 1.1 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 1.5 PID REELIN PATHWAY Reelin signaling pathway
0.0 0.4 NABA COLLAGENS Genes encoding collagen proteins
0.0 2.3 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 1.1 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.4 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.9 PID MAPK TRK PATHWAY Trk receptor signaling mediated by the MAPK pathway
0.0 0.7 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.5 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.6 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.8 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 3.1 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.6 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.8 PID TNF PATHWAY TNF receptor signaling pathway
0.0 0.3 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.5 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 6.0 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.1 1.4 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.1 1.0 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.1 0.3 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.1 2.7 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.1 2.0 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.1 4.3 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors
0.1 2.0 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.1 0.7 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.8 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.9 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 1.0 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 1.6 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.8 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.3 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.9 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 0.6 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 1.0 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 0.4 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 1.1 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.5 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 0.4 REACTOME REGULATION OF INSULIN SECRETION BY GLUCAGON LIKE PEPTIDE1 Genes involved in Regulation of Insulin Secretion by Glucagon-like Peptide-1
0.0 0.8 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 1.7 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.8 REACTOME REGULATION OF INSULIN SECRETION Genes involved in Regulation of Insulin Secretion
0.0 0.2 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.2 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 1.7 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.7 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 1.1 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.2 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.0 0.3 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.2 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 0.7 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.6 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.3 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.0 0.8 REACTOME MUSCLE CONTRACTION Genes involved in Muscle contraction
0.0 0.1 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.2 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation