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2D miR_HR1_12

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Results for Zbtb12

Z-value: 0.47

Motif logo

Transcription factors associated with Zbtb12

Gene Symbol Gene ID Gene Info
ENSMUSG00000049823.8 zinc finger and BTB domain containing 12

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Zbtb12mm10_v2_chr17_+_34894515_34894573-0.821.1e-03Click!

Activity profile of Zbtb12 motif

Sorted Z-values of Zbtb12 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr14_-_13914478 1.05 ENSMUST00000144914.1
predicted gene 281
chr7_-_25539845 1.00 ENSMUST00000066503.7
ENSMUST00000064862.6
carcinoembryonic antigen-related cell adhesion molecule 2
chr7_+_24777172 0.89 ENSMUST00000038069.7
carcinoembryonic antigen-related cell adhesion molecule 10
chr7_-_25539950 0.80 ENSMUST00000044547.8
carcinoembryonic antigen-related cell adhesion molecule 2
chr11_+_54902743 0.75 ENSMUST00000082430.3
glutathione peroxidase 3
chr11_+_54902917 0.68 ENSMUST00000149324.1
glutathione peroxidase 3
chr3_+_27371351 0.66 ENSMUST00000057186.1
growth hormone secretagogue receptor
chr7_-_25477607 0.63 ENSMUST00000098669.1
ENSMUST00000098668.1
ENSMUST00000098666.2
carcinoembryonic antigen-related cell adhesion molecule 1
chr5_-_24447587 0.42 ENSMUST00000127194.1
ENSMUST00000115033.1
ENSMUST00000123167.1
ENSMUST00000030799.8
transmembrane and ubiquitin-like domain containing 1
chr5_+_30281377 0.38 ENSMUST00000101448.3
dynein regulatory complex subunit 1
chr18_-_46728342 0.34 ENSMUST00000035804.7
cysteine dioxygenase 1, cytosolic
chr17_-_28560704 0.31 ENSMUST00000114785.1
ENSMUST00000025062.3
colipase, pancreatic
chr15_-_82690499 0.30 ENSMUST00000100380.3
cytochrome P450, family 2, subfamily d, polypeptide 37, pseudogene
chr17_+_36942910 0.29 ENSMUST00000040498.5
ring finger protein 39
chr15_-_79546741 0.28 ENSMUST00000054014.7
DEAD (Asp-Glu-Ala-Asp) box polypeptide 17
chr17_-_15375969 0.27 ENSMUST00000014917.7
delta-like 1 (Drosophila)
chr11_+_69991061 0.26 ENSMUST00000018711.8
gamma-aminobutyric acid receptor associated protein
chrX_+_107792583 0.25 ENSMUST00000101292.2
family with sequence similarity 46, member D
chr14_+_34220028 0.25 ENSMUST00000119693.1
ENSMUST00000035351.5
synaptotagmin XV
chr17_-_32189457 0.24 ENSMUST00000087721.3
ENSMUST00000162117.1
epoxide hydrolase 3
chr7_-_127993831 0.24 ENSMUST00000033056.3
PYD and CARD domain containing
chr7_-_126976092 0.23 ENSMUST00000181859.1
RIKEN cDNA D830044I16 gene
chr7_+_100176663 0.23 ENSMUST00000178946.1
potassium voltage-gated channel, Isk-related subfamily, gene 3
chrX_+_94724569 0.22 ENSMUST00000101388.2
zinc finger, X-linked, duplicated B
chr4_+_43669266 0.21 ENSMUST00000107864.1
transmembrane protein 8B
chr4_-_43669141 0.21 ENSMUST00000056474.6
family with sequence similarity 221, member B
chr4_-_119173849 0.20 ENSMUST00000052715.4
ENSMUST00000179290.1
ENSMUST00000154226.1
zinc finger protein 691
chr18_+_70472406 0.19 ENSMUST00000114959.2
StAR-related lipid transfer (START) domain containing 6
chr17_+_17831004 0.18 ENSMUST00000172097.2
RIKEN cDNA 4930546H06 gene
chr2_+_43555321 0.18 ENSMUST00000028223.2
kynureninase (L-kynurenine hydrolase)
chr3_-_131344892 0.18 ENSMUST00000090246.4
ENSMUST00000126569.1
sphingomyelin synthase 2
chr5_+_92603039 0.17 ENSMUST00000050952.3
starch binding domain 1
chr11_+_102885160 0.17 ENSMUST00000100369.3
family with sequence similarity 187, member A
chr19_+_46573362 0.17 ENSMUST00000026011.6
sideroflexin 2
chr4_-_138624001 0.16 ENSMUST00000030533.5
von Willebrand factor A domain containing 5B1
chr17_+_36943025 0.16 ENSMUST00000173072.1
ring finger protein 39
chr4_-_10797807 0.16 ENSMUST00000146783.1
RIKEN cDNA 1700123O12 gene
chr15_+_82341179 0.16 ENSMUST00000050349.2
family with sequence similarity 109, member B
chr2_+_109692436 0.15 ENSMUST00000111050.3
brain derived neurotrophic factor
chr19_-_57182293 0.15 ENSMUST00000133369.1
actin-binding LIM protein 1
chr12_+_105784694 0.14 ENSMUST00000109901.2
ENSMUST00000168186.1
ENSMUST00000163473.1
ENSMUST00000170540.1
ENSMUST00000166735.1
ENSMUST00000170002.1
poly (A) polymerase alpha
chr19_-_46573059 0.14 ENSMUST00000026009.8
ADP-ribosylation factor-like 3
chr9_+_22411515 0.14 ENSMUST00000058868.7
RIKEN cDNA 9530077C05 gene
chr6_+_108065035 0.14 ENSMUST00000049246.6
SET domain without mariner transposase fusion
chr15_-_98898483 0.14 ENSMUST00000023737.4
desert hedgehog
chr6_+_90462562 0.13 ENSMUST00000032174.5
Kruppel-like factor 15
chr4_-_133633419 0.12 ENSMUST00000084238.4
zinc finger, DHHC domain containing 18
chr1_-_75232093 0.11 ENSMUST00000180101.1
RIKEN cDNA A630095N17 gene
chr17_+_79626669 0.11 ENSMUST00000086570.1
RIKEN cDNA 4921513D11 gene
chr11_+_49247462 0.10 ENSMUST00000109194.1
mannoside acetylglucosaminyltransferase 1
chr18_+_70472559 0.10 ENSMUST00000168249.2
StAR-related lipid transfer (START) domain containing 6
chr13_+_9276477 0.10 ENSMUST00000174552.1
DIP2 disco-interacting protein 2 homolog C (Drosophila)
chr11_+_109413917 0.09 ENSMUST00000055404.7
RIKEN cDNA 9930022D16 gene
chr7_-_141918481 0.09 ENSMUST00000151890.1
toll interacting protein
chr11_-_98545800 0.09 ENSMUST00000103141.3
IKAROS family zinc finger 3
chr15_+_89499598 0.09 ENSMUST00000109309.1
SH3/ankyrin domain gene 3
chr5_-_35679416 0.08 ENSMUST00000114233.2
HtrA serine peptidase 3
chr6_+_29398920 0.08 ENSMUST00000181464.1
ENSMUST00000180829.1
coiled-coil domain containing 136
chr3_+_5218546 0.07 ENSMUST00000026284.6
zinc finger homeodomain 4
chr15_-_99474696 0.06 ENSMUST00000040313.4
BCDIN3 domain containing
chr17_+_27909337 0.06 ENSMUST00000114842.1
ENSMUST00000025058.7
ENSMUST00000088027.5
ankyrin repeat and SAM domain containing 1
chr6_-_83527986 0.06 ENSMUST00000121731.1
actin, gamma 2, smooth muscle, enteric
chr3_-_130061553 0.06 ENSMUST00000168675.1
Sec24 related gene family, member B (S. cerevisiae)
chr6_+_37900477 0.06 ENSMUST00000120238.1
tripartite motif-containing 24
chr4_-_45489794 0.05 ENSMUST00000146236.1
src homology 2 domain-containing transforming protein B
chr11_-_59228162 0.05 ENSMUST00000163300.1
ENSMUST00000061242.7
ADP-ribosylation factor 1
chr11_-_50916136 0.05 ENSMUST00000116378.1
ENSMUST00000109128.1
zinc finger protein 2
chr1_+_69826986 0.05 ENSMUST00000065425.5
ENSMUST00000113940.2
sperm associated antigen 16
chr18_+_70472660 0.05 ENSMUST00000174118.1
StAR-related lipid transfer (START) domain containing 6
chr1_+_153891646 0.04 ENSMUST00000050660.4
transmembrane epididymal protein 1
chr3_+_5218589 0.03 ENSMUST00000177488.1
zinc finger homeodomain 4
chr5_+_67260696 0.03 ENSMUST00000161233.1
ENSMUST00000160352.1
transmembrane protein 33
chr14_+_79481164 0.03 ENSMUST00000040131.5
E74-like factor 1
chr11_-_59079710 0.03 ENSMUST00000133040.1
obscurin, cytoskeletal calmodulin and titin-interacting RhoGEF
chr17_+_27029259 0.02 ENSMUST00000053683.6
gametogenetin binding protein 1
chr4_+_32983417 0.01 ENSMUST00000084747.5
Ras-related GTP binding D
chr6_-_83527773 0.01 ENSMUST00000152029.1
actin, gamma 2, smooth muscle, enteric
chr18_+_70472621 0.01 ENSMUST00000164223.1
StAR-related lipid transfer (START) domain containing 6
chr3_+_5218516 0.01 ENSMUST00000175866.1
zinc finger homeodomain 4
chr14_+_26693267 0.01 ENSMUST00000022433.4
dynein, axonemal, heavy chain 12
chr5_+_95956916 0.01 ENSMUST00000023840.5
chemokine (C-X-C motif) ligand 13
chr16_-_20302358 0.01 ENSMUST00000048642.8
presenilin associated, rhomboid-like
chr9_+_5308828 0.00 ENSMUST00000162846.1
ENSMUST00000027012.7
caspase 4, apoptosis-related cysteine peptidase
chr5_+_122850186 0.00 ENSMUST00000031434.6
ring finger protein 34
chr8_-_45382198 0.00 ENSMUST00000093526.6
family with sequence similarity 149, member A
chr11_+_100441882 0.00 ENSMUST00000001599.3
ENSMUST00000107395.2
kelch-like 10
chr2_+_31759932 0.00 ENSMUST00000028190.6
c-abl oncogene 1, non-receptor tyrosine kinase

Network of associatons between targets according to the STRING database.

First level regulatory network of Zbtb12

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.8 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.2 0.7 GO:1904349 positive regulation of response to food(GO:0032097) positive regulation of appetite(GO:0032100) hindgut contraction(GO:0043133) regulation of hindgut contraction(GO:0043134) positive regulation of eating behavior(GO:1904000) positive regulation of small intestine smooth muscle contraction(GO:1904349)
0.2 0.6 GO:2000563 positive regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000563)
0.1 0.3 GO:0060846 arterial endothelial cell fate commitment(GO:0060844) blood vessel endothelial cell fate commitment(GO:0060846) endothelial cell fate specification(GO:0060847) Notch signaling pathway involved in arterial endothelial cell fate commitment(GO:0060853) blood vessel endothelial cell fate specification(GO:0097101)
0.1 0.2 GO:0002277 myeloid dendritic cell activation involved in immune response(GO:0002277) positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002582) positive regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002588)
0.1 1.4 GO:0042744 hydrogen peroxide catabolic process(GO:0042744)
0.1 0.3 GO:0033762 response to glucagon(GO:0033762)
0.1 0.2 GO:1902303 negative regulation of potassium ion export(GO:1902303)
0.0 0.1 GO:0061193 taste bud development(GO:0061193)
0.0 0.1 GO:0016539 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908)
0.0 0.1 GO:0019442 tryptophan catabolic process to acetyl-CoA(GO:0019442)
0.0 0.1 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.0 0.3 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.0 0.3 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.1 GO:1901187 regulation of ephrin receptor signaling pathway(GO:1901187)
0.0 0.2 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.4 GO:0060285 cilium or flagellum-dependent cell motility(GO:0001539) cilium-dependent cell motility(GO:0060285)
0.0 0.1 GO:1904717 regulation of AMPA glutamate receptor clustering(GO:1904717)
0.0 0.1 GO:0097212 cleavage furrow ingression(GO:0036090) lysosomal membrane organization(GO:0097212)
0.0 0.1 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.0 0.9 GO:0030317 sperm motility(GO:0030317)
0.0 0.3 GO:0032094 response to food(GO:0032094)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.4 GO:0042101 T cell receptor complex(GO:0042101)
0.1 0.2 GO:0097169 AIM2 inflammasome complex(GO:0097169)
0.0 0.0 GO:1990716 axonemal central apparatus(GO:1990716)
0.0 0.3 GO:0097225 sperm midpiece(GO:0097225)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.4 GO:0008430 selenium binding(GO:0008430)
0.1 2.4 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.1 0.2 GO:2001069 glycogen binding(GO:2001069)
0.0 0.1 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.0 0.2 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.1 GO:0016822 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.0 0.2 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.0 0.1 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.0 0.1 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.0 0.1 GO:0005113 patched binding(GO:0005113)
0.0 0.1 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.1 GO:0005150 interleukin-1, Type I receptor binding(GO:0005150)
0.0 0.3 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.3 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.3 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.7 GO:0017046 peptide hormone binding(GO:0017046)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.7 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0 0.2 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.3 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism