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2D miR_HR1_12

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Results for Fos

Z-value: 0.63

Motif logo

Transcription factors associated with Fos

Gene Symbol Gene ID Gene Info
ENSMUSG00000021250.7 FBJ osteosarcoma oncogene

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Fosmm10_v2_chr12_+_85473883_854738960.078.2e-01Click!

Activity profile of Fos motif

Sorted Z-values of Fos motif

Promoter Log-likelihood Transcript Gene Gene Info
chr7_-_45920830 1.54 ENSMUST00000164119.1
epithelial membrane protein 3
chr6_+_49036518 1.06 ENSMUST00000031840.7
glycoprotein (transmembrane) nmb
chr2_+_13573927 0.83 ENSMUST00000141365.1
ENSMUST00000028062.2
vimentin
chr1_+_107511416 0.82 ENSMUST00000009356.4
serine (or cysteine) peptidase inhibitor, clade B, member 2
chr13_-_56296551 0.79 ENSMUST00000021970.9
chemokine (C-X-C motif) ligand 14
chr1_+_107511489 0.79 ENSMUST00000064916.2
serine (or cysteine) peptidase inhibitor, clade B, member 2
chr6_+_65590382 0.79 ENSMUST00000114236.1
TNFAIP3 interacting protein 3
chr9_+_7445822 0.75 ENSMUST00000034497.6
matrix metallopeptidase 3
chr6_+_7555053 0.70 ENSMUST00000090679.2
ENSMUST00000184986.1
tachykinin 1
chr10_+_97482350 0.68 ENSMUST00000163448.2
decorin
chr19_+_53460610 0.63 ENSMUST00000180442.1
RIKEN cDNA 4833407H14 gene
chr6_+_124996681 0.58 ENSMUST00000032479.4
PILR alpha associated neural protein
chr2_+_24336846 0.58 ENSMUST00000114487.2
interleukin 1 receptor antagonist
chr5_+_30013141 0.54 ENSMUST00000026845.7
interleukin 6
chr9_+_7347374 0.49 ENSMUST00000065079.5
ENSMUST00000005950.5
matrix metallopeptidase 12
chr16_+_32400506 0.46 ENSMUST00000115149.2
transmembrane 4 L six family member 19
chr11_+_82045705 0.46 ENSMUST00000021011.2
chemokine (C-C motif) ligand 7
chr14_+_65968483 0.42 ENSMUST00000022616.6
clusterin
chr9_+_69453620 0.39 ENSMUST00000034756.8
ENSMUST00000123470.1
annexin A2
chr14_-_54712139 0.36 ENSMUST00000064290.6
CCAAT/enhancer binding protein (C/EBP), epsilon
chr2_-_29253001 0.36 ENSMUST00000071201.4
netrin G2
chr7_+_30763750 0.36 ENSMUST00000165887.1
ENSMUST00000085691.4
ENSMUST00000085688.4
ENSMUST00000054427.6
dermokine
chr9_-_106476372 0.35 ENSMUST00000123555.1
ENSMUST00000125850.1
poly (ADP-ribose) polymerase family, member 3
chr2_+_91257323 0.35 ENSMUST00000111349.2
ENSMUST00000131711.1
protein kinase C and casein kinase substrate in neurons 3
chr4_+_42158092 0.34 ENSMUST00000098122.2
predicted gene 13306
chr8_-_25091341 0.34 ENSMUST00000125466.1
pleckstrin homology domain-containing, family A (phosphoinositide binding specific) member 2
chr6_-_122856151 0.34 ENSMUST00000042081.8
complement component 3a receptor 1
chr10_-_76725978 0.34 ENSMUST00000001147.4
collagen, type VI, alpha 1
chr7_+_30776394 0.33 ENSMUST00000041703.7
dermokine
chr7_-_126594941 0.33 ENSMUST00000058429.5
interleukin 27
chr11_-_100261021 0.32 ENSMUST00000080893.6
keratin 17
chr7_+_139834148 0.32 ENSMUST00000026548.7
G protein-coupled receptor 123
chr7_-_4970961 0.31 ENSMUST00000144863.1
predicted gene 1078
chr7_+_128129536 0.31 ENSMUST00000033053.6
integrin alpha X
chr10_+_128790903 0.31 ENSMUST00000026411.6
matrix metallopeptidase 19
chr6_+_135362931 0.30 ENSMUST00000032330.9
epithelial membrane protein 1
chr2_+_69380431 0.30 ENSMUST00000063690.3
dehydrogenase/reductase (SDR family) member 9
chr17_-_57194170 0.29 ENSMUST00000005976.6
tumor necrosis factor (ligand) superfamily, member 14
chr11_-_69666062 0.27 ENSMUST00000108654.2
ENSMUST00000018918.5
CD68 antigen
chr3_-_10208569 0.26 ENSMUST00000029041.4
fatty acid binding protein 4, adipocyte
chr7_-_31042078 0.26 ENSMUST00000162116.1
ENSMUST00000159924.1
ENSMUST00000159753.1
ENSMUST00000160689.1
ENSMUST00000162733.1
ENSMUST00000162087.1
ENSMUST00000009831.7
FXYD domain-containing ion transport regulator 5
chr3_+_100825452 0.26 ENSMUST00000054791.7
V-set domain containing T cell activation inhibitor 1
chr7_+_27486910 0.26 ENSMUST00000008528.7
SERTA domain containing 1
chr11_-_99155067 0.26 ENSMUST00000103134.3
chemokine (C-C motif) receptor 7
chr12_+_10369967 0.26 ENSMUST00000118657.1
ENSMUST00000143739.1
ENSMUST00000002456.8
5'-nucleotidase, cytosolic IB
chr2_-_102451792 0.25 ENSMUST00000099678.3
four jointed box 1 (Drosophila)
chr2_-_34958129 0.25 ENSMUST00000172159.1
TNF receptor-associated factor 1
chr8_+_4226827 0.25 ENSMUST00000053035.6
leucine rich repeat containing 8 family, member E
chr11_+_95842668 0.25 ENSMUST00000100532.3
ENSMUST00000036088.4
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2
chr1_+_171559186 0.25 ENSMUST00000004829.7
CD244 natural killer cell receptor 2B4
chr1_+_74125535 0.24 ENSMUST00000080167.4
ENSMUST00000127134.1
RUN and FYVE domain containing 4
chr9_-_106476590 0.24 ENSMUST00000112479.2
poly (ADP-ribose) polymerase family, member 3
chr11_+_116533257 0.24 ENSMUST00000154034.1
sphingosine kinase 1
chr11_-_106973090 0.24 ENSMUST00000150366.1
predicted gene 11707
chr12_+_80518990 0.24 ENSMUST00000021558.6
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 16
chr9_+_108953578 0.23 ENSMUST00000112070.1
collagen, type VII, alpha 1
chr16_-_29946499 0.23 ENSMUST00000181968.1
predicted gene, 26569
chr7_-_142372342 0.23 ENSMUST00000059223.8
interferon induced transmembrane protein 10
chr3_-_95739544 0.23 ENSMUST00000153026.1
ENSMUST00000123143.1
ENSMUST00000137912.1
ENSMUST00000029753.6
ENSMUST00000131376.1
ENSMUST00000117507.2
ENSMUST00000128885.1
ENSMUST00000147217.1
extracellular matrix protein 1
chr7_-_142372210 0.23 ENSMUST00000084412.5
interferon induced transmembrane protein 10
chr10_-_128298084 0.23 ENSMUST00000026449.1
interleukin 23, alpha subunit p19
chr11_+_95842283 0.22 ENSMUST00000107714.2
ENSMUST00000107711.1
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2
chr19_+_5877794 0.22 ENSMUST00000145200.1
ENSMUST00000025732.7
ENSMUST00000125114.1
ENSMUST00000155697.1
solute carrier family 25, member 45
chr13_+_95696851 0.22 ENSMUST00000022182.4
coagulation factor II (thrombin) receptor-like 2
chr6_+_29529277 0.22 ENSMUST00000163511.1
interferon regulatory factor 5
chr19_+_8850785 0.22 ENSMUST00000096257.2
LRRN4 C-terminal like
chr15_-_103366763 0.22 ENSMUST00000023128.6
integrin alpha 5 (fibronectin receptor alpha)
chr11_+_116531744 0.22 ENSMUST00000106387.2
ENSMUST00000100201.3
sphingosine kinase 1
chr14_-_41185188 0.21 ENSMUST00000077136.3
surfactant associated protein D
chr7_+_24370255 0.21 ENSMUST00000171904.1
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr4_-_133602168 0.21 ENSMUST00000057311.3
stratifin
chr2_+_52038005 0.21 ENSMUST00000065927.5
tumor necrosis factor alpha induced protein 6
chr2_+_25395866 0.21 ENSMUST00000028328.2
ectonucleoside triphosphate diphosphohydrolase 2
chr7_+_92741603 0.21 ENSMUST00000032879.7
RAB30, member RAS oncogene family
chr7_-_143502515 0.20 ENSMUST00000010904.4
pleckstrin homology-like domain, family A, member 2
chr3_+_102469918 0.20 ENSMUST00000106925.2
ENSMUST00000035952.3
nerve growth factor
chrX_-_7740206 0.20 ENSMUST00000128289.1
coiled-coil domain containing 120
chr7_-_31041777 0.20 ENSMUST00000161805.1
FXYD domain-containing ion transport regulator 5
chrX_-_167209149 0.20 ENSMUST00000112176.1
thymosin, beta 4, X chromosome
chr7_-_126369543 0.20 ENSMUST00000032997.6
linker for activation of T cells
chr6_+_53573364 0.20 ENSMUST00000047450.7
cAMP responsive element binding protein 5
chr19_+_8989277 0.20 ENSMUST00000092955.3
ENSMUST00000092956.2
AHNAK nucleoprotein (desmoyokin)
chr6_-_129507107 0.20 ENSMUST00000183258.1
ENSMUST00000182784.1
ENSMUST00000032265.6
ENSMUST00000162815.1
oxidized low density lipoprotein (lectin-like) receptor 1
chr4_-_127358124 0.20 ENSMUST00000046498.2
gap junction protein, beta 5
chr9_+_108953597 0.20 ENSMUST00000026740.5
collagen, type VII, alpha 1
chr3_+_109573907 0.19 ENSMUST00000106576.2
vav 3 oncogene
chr6_+_42349826 0.19 ENSMUST00000070635.6
zyxin
chr9_+_7692086 0.19 ENSMUST00000018767.7
matrix metallopeptidase 7
chrX_-_134583114 0.18 ENSMUST00000113213.1
ENSMUST00000033617.6
Bruton agammaglobulinemia tyrosine kinase
chr19_-_58455903 0.17 ENSMUST00000131877.1
glial cell line derived neurotrophic factor family receptor alpha 1
chr14_-_70177668 0.17 ENSMUST00000022681.4
PDZ and LIM domain 2
chr3_-_92485886 0.16 ENSMUST00000054599.7
small proline-rich protein 1A
chr17_+_47769191 0.16 ENSMUST00000160373.1
ENSMUST00000159641.1
transcription factor EB
chr1_-_155527083 0.16 ENSMUST00000097531.2
predicted gene 5532
chr11_-_97150025 0.16 ENSMUST00000118375.1
TBK1 binding protein 1
chr7_-_29248375 0.16 ENSMUST00000032808.4
RIKEN cDNA 2200002D01 gene
chr5_-_24392012 0.15 ENSMUST00000059401.6
autophagy related 9B
chr16_-_44558864 0.15 ENSMUST00000023370.4
biregional cell adhesion molecule-related/down-regulated by oncogenes (Cdon) binding protein
chrX_-_143827391 0.15 ENSMUST00000087316.5
calpain 6
chr9_-_119977250 0.15 ENSMUST00000035101.7
cysteine-serine-rich nuclear protein 1
chr19_-_34166037 0.15 ENSMUST00000025686.7
ankyrin repeat domain 22
chr2_-_36105271 0.15 ENSMUST00000112960.1
ENSMUST00000112967.5
ENSMUST00000112963.1
LIM homeobox protein 6
chr1_+_131962941 0.15 ENSMUST00000177943.1
solute carrier family 45, member 3
chr7_+_44816364 0.15 ENSMUST00000118125.1
interleukin 4 induced 1
chr7_+_110772604 0.15 ENSMUST00000005829.6
adenosine monophosphate deaminase 3
chr15_-_102257449 0.15 ENSMUST00000043172.8
retinoic acid receptor, gamma
chr11_-_23519181 0.14 ENSMUST00000020527.5
RIKEN cDNA 1700093K21 gene
chr9_+_78615501 0.14 ENSMUST00000093812.4
CD109 antigen
chr6_-_129533267 0.14 ENSMUST00000181594.1
RIKEN cDNA 1700101I11 gene
chr5_+_100846130 0.13 ENSMUST00000112887.1
ENSMUST00000031255.8
1-acylglycerol-3-phosphate O-acyltransferase 9
chr13_-_62858364 0.13 ENSMUST00000021907.7
fructose bisphosphatase 2
chr2_+_164948219 0.13 ENSMUST00000017881.2
matrix metallopeptidase 9
chr10_-_19015347 0.13 ENSMUST00000019997.4
tumor necrosis factor, alpha-induced protein 3
chr7_+_126776939 0.13 ENSMUST00000038614.5
ENSMUST00000170882.1
ENSMUST00000106359.1
ENSMUST00000106357.1
ENSMUST00000145762.1
ENSMUST00000132643.1
ENSMUST00000106356.1
yippee-like 3 (Drosophila)
chr16_-_44558879 0.13 ENSMUST00000114634.1
biregional cell adhesion molecule-related/down-regulated by oncogenes (Cdon) binding protein
chr3_+_55461758 0.13 ENSMUST00000070418.4
doublecortin-like kinase 1
chr16_+_78930940 0.13 ENSMUST00000114216.1
ENSMUST00000069148.6
ENSMUST00000023568.7
chondrolectin
chr9_+_51213683 0.12 ENSMUST00000034554.7
POU domain, class 2, associating factor 1
chr15_-_9529868 0.12 ENSMUST00000003981.4
interleukin 7 receptor
chr1_-_22805994 0.12 ENSMUST00000097808.4
regulating synaptic membrane exocytosis 1
chr14_-_33185066 0.12 ENSMUST00000061753.8
ENSMUST00000130509.2
WD repeat and FYVE domain containing 4
chr8_+_122282117 0.12 ENSMUST00000054052.8
zinc finger protein, multitype 1
chrX_+_133908441 0.12 ENSMUST00000113304.1
sushi-repeat-containing protein, X-linked 2
chr8_+_88289028 0.12 ENSMUST00000171456.1
adenylate cyclase 7
chr1_+_186967416 0.12 ENSMUST00000045108.1
DNA segment, Chr 1, Pasteur Institute 1
chr2_-_77703252 0.11 ENSMUST00000171063.1
zinc finger protein 385B
chr7_+_126584937 0.11 ENSMUST00000039522.6
apolipoprotein B receptor
chr9_+_7272514 0.11 ENSMUST00000015394.8
matrix metallopeptidase 13
chr7_-_105482197 0.11 ENSMUST00000047040.2
protein kinase C, delta binding protein
chrX_+_112615301 0.11 ENSMUST00000122805.1
zinc finger protein 711
chr17_+_70561739 0.11 ENSMUST00000097288.2
discs, large (Drosophila) homolog-associated protein 1
chr4_-_43040279 0.11 ENSMUST00000107958.1
ENSMUST00000107959.1
ENSMUST00000152846.1
family with sequence similarity 214, member B
chr2_+_118663235 0.10 ENSMUST00000099557.3
p21 protein (Cdc42/Rac)-activated kinase 6
chr5_+_100846364 0.10 ENSMUST00000092990.3
ENSMUST00000145612.1
1-acylglycerol-3-phosphate O-acyltransferase 9
chr2_-_164404606 0.10 ENSMUST00000109359.1
ENSMUST00000109358.1
ENSMUST00000103103.3
matrilin 4
chr7_+_67647405 0.10 ENSMUST00000032774.8
ENSMUST00000107471.1
tetratricopeptide repeat domain 23
chr3_+_14641722 0.10 ENSMUST00000029071.8
carbonic anhydrase 13
chr3_+_138217814 0.10 ENSMUST00000090171.5
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr17_+_12119274 0.10 ENSMUST00000024594.2
1-acylglycerol-3-phosphate O-acyltransferase 4 (lysophosphatidic acid acyltransferase, delta)
chrX_+_98149666 0.10 ENSMUST00000052837.7
androgen receptor
chr9_-_96752653 0.10 ENSMUST00000062899.3
RIKEN cDNA E030011O05 gene
chr1_+_17601893 0.10 ENSMUST00000088476.2
peptidase inhibitor 15
chr14_-_12345847 0.09 ENSMUST00000022262.4
Fez family zinc finger 2
chr13_-_65205716 0.09 ENSMUST00000037372.7
NLR family, pyrin domain containing 4F
chr6_-_113434757 0.09 ENSMUST00000113091.1
cell death-inducing DFFA-like effector c
chr1_+_59516264 0.09 ENSMUST00000114243.1
predicted gene 973
chr11_-_100207507 0.09 ENSMUST00000007272.7
keratin 14
chr5_-_62766153 0.09 ENSMUST00000076623.4
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr9_+_106499967 0.09 ENSMUST00000164965.1
ENSMUST00000085114.5
IQ motif containing F1
chr15_+_102503722 0.09 ENSMUST00000096145.4
predicted gene 10337
chr7_-_102250086 0.09 ENSMUST00000106923.1
ENSMUST00000098230.4
ras homolog gene family, member G
chr6_+_42350000 0.09 ENSMUST00000164375.1
zyxin
chr16_-_4880284 0.09 ENSMUST00000037843.6
UBA-like domain containing 1
chr5_+_34999070 0.09 ENSMUST00000114280.1
regulator of G-protein signaling 12
chr1_-_33907721 0.09 ENSMUST00000115161.1
ENSMUST00000062289.8
BEN domain containing 6
chr13_+_15463837 0.08 ENSMUST00000110510.3
GLI-Kruppel family member GLI3
chrX_-_147429189 0.08 ENSMUST00000033646.2
interleukin 13 receptor, alpha 2
chr4_-_140665891 0.08 ENSMUST00000069623.5
Rho guanine nucleotide exchange factor (GEF) 10-like
chr4_-_133212480 0.08 ENSMUST00000052090.8
G-protein coupled receptor 3
chr18_+_42053648 0.08 ENSMUST00000072008.4
SH3 domain containing ring finger 2
chr11_-_51650813 0.08 ENSMUST00000142721.1
ENSMUST00000156835.1
ENSMUST00000001080.9
NEDD4 binding protein 3
chr10_+_21993890 0.08 ENSMUST00000092673.4
serum/glucocorticoid regulated kinase 1
chr18_+_42053692 0.08 ENSMUST00000074679.3
SH3 domain containing ring finger 2
chr15_+_84669565 0.08 ENSMUST00000171460.1
proline rich 5 (renal)
chr10_+_80930071 0.08 ENSMUST00000015456.8
growth arrest and DNA-damage-inducible 45 beta
chr14_-_21748610 0.08 ENSMUST00000075040.2
ENSMUST00000183943.1
dual specificity phosphatase 13
chr9_+_44240668 0.08 ENSMUST00000092426.3
coiled-coil domain containing 153
chrX_+_6415736 0.08 ENSMUST00000143641.3
shroom family member 4
chr1_-_10719898 0.08 ENSMUST00000035577.6
carboxypeptidase A6
chr15_-_97767798 0.07 ENSMUST00000129223.2
ENSMUST00000126854.2
ENSMUST00000135080.1
Rap guanine nucleotide exchange factor (GEF) 3
chr6_+_4755327 0.07 ENSMUST00000176551.1
paternally expressed 10
chr7_+_127244511 0.07 ENSMUST00000052509.4
zinc finger protein 771
chr6_-_124769548 0.07 ENSMUST00000149652.1
ENSMUST00000112476.1
ENSMUST00000004378.8
enolase 2, gamma neuronal
chr10_-_128498676 0.07 ENSMUST00000026428.3
myosin, light polypeptide 6B
chr5_+_34999046 0.07 ENSMUST00000114281.1
regulator of G-protein signaling 12
chr17_-_44814649 0.07 ENSMUST00000113571.3
runt related transcription factor 2
chr11_+_78188422 0.07 ENSMUST00000002128.7
ENSMUST00000150941.1
RAB34, member of RAS oncogene family
chr11_+_97018733 0.07 ENSMUST00000107622.1
trans-acting transcription factor 6
chr7_+_141079759 0.07 ENSMUST00000066873.4
ENSMUST00000163041.1
plakophilin 3
chr6_-_35326123 0.07 ENSMUST00000051176.7
family with sequence similarity 180, member A
chr19_+_46305682 0.07 ENSMUST00000111881.2
nuclear factor of kappa light polypeptide gene enhancer in B cells 2, p49/p100
chr2_-_45110336 0.07 ENSMUST00000028229.6
ENSMUST00000152232.1
zinc finger E-box binding homeobox 2
chr1_+_40515362 0.06 ENSMUST00000027237.5
interleukin 18 receptor accessory protein
chr19_+_5050807 0.06 ENSMUST00000025818.6
Ras and Rab interactor 1
chr14_+_34310727 0.06 ENSMUST00000022322.9
glutamate dehydrogenase 1
chr6_+_17463749 0.06 ENSMUST00000115443.1
met proto-oncogene
chr2_-_45110241 0.06 ENSMUST00000177302.1
zinc finger E-box binding homeobox 2
chr10_-_42583628 0.06 ENSMUST00000019938.4
nuclear receptor subfamily 2, group E, member 1
chr4_+_150927918 0.06 ENSMUST00000139826.1
ENSMUST00000116257.1
tumor necrosis factor receptor superfamily, member 9
chr16_-_97962581 0.06 ENSMUST00000113734.2
ENSMUST00000052089.7
ENSMUST00000063605.7
zinc finger and BTB domain containing 21
chr6_+_95117740 0.06 ENSMUST00000032107.7
ENSMUST00000119582.1
kelch repeat and BTB (POZ) domain containing 8
chr2_+_103411682 0.06 ENSMUST00000164172.1
E74-like factor 5
chr17_-_47834682 0.06 ENSMUST00000066368.6
MyoD family inhibitor
chr6_-_122282810 0.06 ENSMUST00000032207.8
killer cell lectin-like receptor subfamily G, member 1
chr16_+_35770382 0.06 ENSMUST00000023555.4
Hspb associated protein 1
chr2_+_30078584 0.06 ENSMUST00000045246.7
protein kinase N3
chr2_+_61711694 0.06 ENSMUST00000028278.7
proteasome (prosome, macropain) 26S subunit, non-ATPase, 14
chr8_-_61591130 0.06 ENSMUST00000135439.1
ENSMUST00000121200.1
palladin, cytoskeletal associated protein
chr10_-_44004846 0.06 ENSMUST00000020017.8
absent in melanoma 1
chr17_+_75178911 0.06 ENSMUST00000112514.1
latent transforming growth factor beta binding protein 1

Network of associatons between targets according to the STRING database.

First level regulatory network of Fos

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:2000852 corticosterone secretion(GO:0035934) regulation of corticosterone secretion(GO:2000852)
0.2 1.1 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.2 0.8 GO:2000503 positive regulation of natural killer cell chemotaxis(GO:2000503)
0.2 0.6 GO:1990166 protein localization to site of double-strand break(GO:1990166)
0.2 0.7 GO:1903575 cornified envelope assembly(GO:1903575)
0.2 0.8 GO:0036135 Schwann cell migration(GO:0036135) regulation of Schwann cell migration(GO:1900147)
0.1 0.3 GO:2000410 regulation of thymocyte migration(GO:2000410) positive regulation of thymocyte migration(GO:2000412)
0.1 0.2 GO:0071661 granzyme B production(GO:0071613) regulation of granzyme B production(GO:0071661) positive regulation of granzyme B production(GO:0071663)
0.1 0.3 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.1 0.7 GO:1900747 negative regulation of vascular endothelial growth factor signaling pathway(GO:1900747)
0.1 1.8 GO:0032060 bleb assembly(GO:0032060)
0.1 0.6 GO:0044359 modulation of molecular function in other organism(GO:0044359) negative regulation of molecular function in other organism(GO:0044362) negative regulation of molecular function in other organism involved in symbiotic interaction(GO:0052204) modulation of molecular function in other organism involved in symbiotic interaction(GO:0052205) negative regulation by host of symbiont molecular function(GO:0052405) modification by host of symbiont molecular function(GO:0052428)
0.1 0.5 GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.1 0.8 GO:0002756 MyD88-independent toll-like receptor signaling pathway(GO:0002756)
0.1 0.5 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.1 0.2 GO:2000328 regulation of memory T cell differentiation(GO:0043380) regulation of T-helper 17 cell lineage commitment(GO:2000328)
0.1 0.7 GO:0010727 negative regulation of hydrogen peroxide metabolic process(GO:0010727)
0.1 0.4 GO:1902847 regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.1 0.3 GO:0002461 tolerance induction dependent upon immune response(GO:0002461)
0.1 0.1 GO:0046351 disaccharide biosynthetic process(GO:0046351)
0.1 0.2 GO:0002777 antimicrobial peptide biosynthetic process(GO:0002777) antibacterial peptide biosynthetic process(GO:0002780)
0.1 0.2 GO:0002343 peripheral B cell selection(GO:0002343) B cell affinity maturation(GO:0002344)
0.1 0.1 GO:0035793 positive regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:0035793) regulation of metanephric mesenchymal cell migration by platelet-derived growth factor receptor-beta signaling pathway(GO:1900238) positive regulation of metanephric mesenchymal cell migration(GO:2000591)
0.0 0.1 GO:0015770 disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.0 0.1 GO:0002631 regulation of granuloma formation(GO:0002631) negative regulation of granuloma formation(GO:0002632) regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070425) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429) negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070433) tolerance induction to lipopolysaccharide(GO:0072573)
0.0 0.3 GO:0042904 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0 0.6 GO:0071361 cellular response to ethanol(GO:0071361)
0.0 0.2 GO:0090214 spongiotrophoblast layer developmental growth(GO:0090214)
0.0 0.2 GO:0021853 cerebral cortex GABAergic interneuron migration(GO:0021853) interneuron migration(GO:1904936)
0.0 0.2 GO:0009816 defense response to bacterium, incompatible interaction(GO:0009816) regulation of defense response to bacterium, incompatible interaction(GO:1902477)
0.0 0.2 GO:0003430 growth plate cartilage chondrocyte growth(GO:0003430)
0.0 1.3 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.0 0.7 GO:0031424 keratinization(GO:0031424)
0.0 0.4 GO:0045078 regulation of interferon-gamma biosynthetic process(GO:0045072) positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.0 0.2 GO:1905161 protein localization to phagocytic vesicle(GO:1905161) regulation of protein localization to phagocytic vesicle(GO:1905169) positive regulation of protein localization to phagocytic vesicle(GO:1905171)
0.0 0.1 GO:0060748 positive regulation of integrin biosynthetic process(GO:0045726) lateral sprouting involved in mammary gland duct morphogenesis(GO:0060599) tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.0 0.3 GO:1900042 interleukin-4 secretion(GO:0072602) positive regulation of interleukin-2 secretion(GO:1900042)
0.0 0.2 GO:0044805 late nucleophagy(GO:0044805)
0.0 0.1 GO:0010808 positive regulation of synaptic vesicle priming(GO:0010808)
0.0 0.1 GO:0072675 osteoclast fusion(GO:0072675)
0.0 0.1 GO:0090187 positive regulation of pancreatic juice secretion(GO:0090187)
0.0 0.1 GO:1904451 regulation of hydrogen:potassium-exchanging ATPase activity(GO:1904451) positive regulation of hydrogen:potassium-exchanging ATPase activity(GO:1904453)
0.0 0.1 GO:0038032 termination of G-protein coupled receptor signaling pathway(GO:0038032)
0.0 0.2 GO:0009137 purine nucleoside diphosphate catabolic process(GO:0009137) purine ribonucleoside diphosphate catabolic process(GO:0009181)
0.0 0.1 GO:0006069 ethanol oxidation(GO:0006069)
0.0 0.1 GO:1902093 positive regulation of sperm motility(GO:1902093)
0.0 0.3 GO:0071285 cellular response to lithium ion(GO:0071285)
0.0 0.1 GO:0002266 follicular dendritic cell activation(GO:0002266) follicular dendritic cell differentiation(GO:0002268)
0.0 0.3 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.1 GO:0061373 mammillary body development(GO:0021767) mammillary axonal complex development(GO:0061373) positive regulation of lens fiber cell differentiation(GO:1902748)
0.0 0.1 GO:2001183 negative regulation of interleukin-12 secretion(GO:2001183)
0.0 0.1 GO:0001712 ectodermal cell fate commitment(GO:0001712)
0.0 0.0 GO:1902724 positive regulation of skeletal muscle satellite cell proliferation(GO:1902724) positive regulation of growth factor dependent skeletal muscle satellite cell proliferation(GO:1902728)
0.0 0.4 GO:0030574 collagen catabolic process(GO:0030574)
0.0 0.2 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
0.0 0.1 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.0 0.2 GO:0050862 positive regulation of T cell receptor signaling pathway(GO:0050862)
0.0 0.1 GO:0032264 purine nucleotide salvage(GO:0032261) IMP salvage(GO:0032264)
0.0 0.1 GO:2000774 positive regulation of cellular senescence(GO:2000774)
0.0 0.0 GO:0071336 regulation of hair follicle cell proliferation(GO:0071336)
0.0 0.2 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0 0.1 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.0 0.3 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.3 GO:0070208 protein heterotrimerization(GO:0070208)
0.0 0.0 GO:0032792 negative regulation of CREB transcription factor activity(GO:0032792) negative regulation of determination of dorsal identity(GO:2000016)
0.0 0.1 GO:0021776 optic nerve morphogenesis(GO:0021631) smoothened signaling pathway involved in ventral spinal cord interneuron specification(GO:0021775) smoothened signaling pathway involved in spinal cord motor neuron cell fate specification(GO:0021776) mammary gland specification(GO:0060594)
0.0 0.1 GO:0002159 desmosome assembly(GO:0002159)
0.0 0.1 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.1 GO:0006538 glutamate catabolic process(GO:0006538)
0.0 0.2 GO:0006968 cellular defense response(GO:0006968)
0.0 0.1 GO:0021764 amygdala development(GO:0021764)
0.0 0.2 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.0 0.0 GO:0030043 actin filament fragmentation(GO:0030043)
0.0 0.0 GO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.0 0.1 GO:0060591 chondroblast differentiation(GO:0060591)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.1 0.4 GO:1990667 PCSK9-AnxA2 complex(GO:1990667)
0.1 0.8 GO:0045098 type III intermediate filament(GO:0045098)
0.0 0.7 GO:0098644 complex of collagen trimers(GO:0098644)
0.0 0.4 GO:0097418 neurofibrillary tangle(GO:0097418)
0.0 0.1 GO:0038045 large latent transforming growth factor-beta complex(GO:0038045)
0.0 0.1 GO:0005914 spot adherens junction(GO:0005914)
0.0 0.1 GO:0097574 lateral part of cell(GO:0097574) basolateral part of cell(GO:1990794) rod bipolar cell terminal bouton(GO:1990795)
0.0 0.1 GO:0098831 presynaptic active zone cytoplasmic component(GO:0098831)
0.0 0.1 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.0 0.1 GO:0005927 muscle tendon junction(GO:0005927)
0.0 0.0 GO:0036488 CHOP-C/EBP complex(GO:0036488)
0.0 0.6 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.2 GO:0001533 cornified envelope(GO:0001533)
0.0 1.0 GO:0005581 collagen trimer(GO:0005581)
0.0 0.5 GO:0008305 integrin complex(GO:0008305)
0.0 0.0 GO:1990590 ATF1-ATF4 transcription factor complex(GO:1990590)
0.0 0.0 GO:0070436 Grb2-EGFR complex(GO:0070436)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0045352 interleukin-1, Type II receptor binding(GO:0005151) interleukin-1 receptor antagonist activity(GO:0005152) interleukin-1 Type I receptor antagonist activity(GO:0045352) interleukin-1 Type II receptor antagonist activity(GO:0045353)
0.2 0.8 GO:1990254 keratin filament binding(GO:1990254)
0.1 1.1 GO:0045545 syndecan binding(GO:0045545)
0.1 0.5 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.1 0.4 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.1 0.4 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.1 0.6 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.1 0.5 GO:0017050 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.1 0.5 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.1 0.2 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.1 0.2 GO:0015057 thrombin receptor activity(GO:0015057)
0.1 0.2 GO:0030280 structural constituent of epidermis(GO:0030280)
0.1 0.2 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.1 0.2 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.0 0.1 GO:0008506 sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.0 0.1 GO:0001716 L-amino-acid oxidase activity(GO:0001716)
0.0 0.3 GO:0004875 complement receptor activity(GO:0004875)
0.0 0.3 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.3 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 0.4 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.3 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.1 GO:0050436 microfibril binding(GO:0050436)
0.0 0.8 GO:0008009 chemokine activity(GO:0008009)
0.0 0.7 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.0 0.2 GO:0043262 adenosine-diphosphatase activity(GO:0043262)
0.0 2.0 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.1 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.0 0.2 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 0.1 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 1.0 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.4 GO:0051787 misfolded protein binding(GO:0051787)
0.0 0.1 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.3 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.1 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.3 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.2 GO:0097493 structural molecule activity conferring elasticity(GO:0097493)
0.0 0.2 GO:0042288 MHC class I protein binding(GO:0042288)
0.0 0.0 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.0 0.1 GO:0070728 leucine binding(GO:0070728)
0.0 0.1 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.8 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.6 ST STAT3 PATHWAY STAT3 Pathway
0.0 0.1 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 0.5 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 0.5 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.7 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.7 PID AURORA B PATHWAY Aurora B signaling
0.0 0.2 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 0.3 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.0 0.2 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.3 PID IL23 PATHWAY IL23-mediated signaling events
0.0 0.3 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.7 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 0.3 PID IL27 PATHWAY IL27-mediated signaling events
0.0 0.3 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.2 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.6 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 1.1 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.8 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.3 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.1 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.7 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.7 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0 0.2 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.3 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.2 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.0 0.1 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.8 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 1.0 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors