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2D miR_HR1_12

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Results for Sox1

Z-value: 0.48

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Transcription factors associated with Sox1

Gene Symbol Gene ID Gene Info
ENSMUSG00000096014.1 SRY (sex determining region Y)-box 1

Activity profile of Sox1 motif

Sorted Z-values of Sox1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr7_-_127890918 1.10 ENSMUST00000121394.1
protease, serine, 53
chrX_+_164162167 0.62 ENSMUST00000131543.1
angiotensin I converting enzyme (peptidyl-dipeptidase A) 2
chr9_-_108305941 0.41 ENSMUST00000044725.7
T cell leukemia translocation altered gene
chr6_+_37530173 0.41 ENSMUST00000040987.7
aldo-keto reductase family 1, member D1
chr17_+_34263209 0.37 ENSMUST00000040828.5
histocompatibility 2, class II antigen A, beta 1
chr2_+_84798828 0.37 ENSMUST00000102642.2
ENSMUST00000150325.1
ubiquitin-conjugating enzyme E2L 6
chr8_+_13159135 0.36 ENSMUST00000033824.6
lysosomal-associated membrane protein 1
chr9_+_44326804 0.35 ENSMUST00000054708.3
dolichyl-phosphate (UDP-N-acetylglucosamine) acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase)
chr8_+_83165348 0.32 ENSMUST00000034145.4
TBC1 domain family, member 9
chr8_-_88636117 0.31 ENSMUST00000034087.7
sorting nexin 20
chr17_-_47692466 0.29 ENSMUST00000113300.1
prickle homolog 4 (Drosophila)
chr17_-_34287770 0.28 ENSMUST00000174751.1
ENSMUST00000040655.6
histocompatibility 2, class II antigen A, alpha
chr19_-_8218832 0.28 ENSMUST00000113298.2
solute carrier family 22. member 29
chr7_+_80343091 0.26 ENSMUST00000032747.5
HD domain containing 3
chr15_-_75048837 0.24 ENSMUST00000179762.1
ENSMUST00000065408.9
lymphocyte antigen 6 complex, locus C1
chr4_-_120747248 0.23 ENSMUST00000030376.7
potassium voltage-gated channel, subfamily Q, member 4
chr11_-_68853119 0.21 ENSMUST00000018880.7
nuclear distribution gene E-like homolog 1 (A. nidulans)
chr15_-_74997634 0.20 ENSMUST00000023248.6
lymphocyte antigen 6 complex, locus A
chrX_+_74297097 0.20 ENSMUST00000019231.5
ENSMUST00000147900.1
ENSMUST00000147275.1
ENSMUST00000114171.3
ATPase, H+ transporting, lysosomal accessory protein 1
chr7_+_41633531 0.19 ENSMUST00000100275.3
ENSMUST00000131180.1
ENSMUST00000140964.1
ENSMUST00000045720.7
ENSMUST00000098508.2
zinc finger protein 788
chr4_+_136357423 0.19 ENSMUST00000182167.1
predicted gene, 17388
chr5_-_109691041 0.19 ENSMUST00000092720.3
RIKEN cDNA 5430403G16 gene
chr17_-_33033367 0.19 ENSMUST00000087654.4
zinc finger protein 763
chr17_+_47737030 0.18 ENSMUST00000086932.3
transcription factor EB
chr18_+_37496997 0.18 ENSMUST00000059571.5
protocadherin beta 19
chr13_+_42301270 0.16 ENSMUST00000021796.7
endothelin 1
chr9_+_124121534 0.16 ENSMUST00000111442.1
ENSMUST00000171499.2
chemokine (C-C motif) receptor 5
chr11_-_69878018 0.15 ENSMUST00000178597.1
transmembrane protein 95
chr7_-_46919915 0.14 ENSMUST00000143413.1
ENSMUST00000014546.8
tumor susceptibility gene 101
chr1_+_109983737 0.12 ENSMUST00000172005.1
cadherin 7, type 2
chr13_-_95478655 0.11 ENSMUST00000022186.3
S100 calcium binding protein, zeta
chr5_+_21186267 0.11 ENSMUST00000036031.8
gamma-secretase activating protein
chr1_+_171895664 0.10 ENSMUST00000097466.2
predicted gene 10521
chr11_-_68853019 0.09 ENSMUST00000108672.1
nuclear distribution gene E-like homolog 1 (A. nidulans)
chr1_-_195131536 0.09 ENSMUST00000075451.6
complement component (3b/4b) receptor 1-like
chr9_+_123767211 0.09 ENSMUST00000166236.1
ENSMUST00000111454.2
ENSMUST00000168910.1
chemokine (C-C motif) receptor 9
chrX_+_112600526 0.06 ENSMUST00000113409.1
zinc finger protein 711
chr10_-_18785011 0.05 ENSMUST00000055107.6
predicted gene 4922
chr6_+_117841174 0.05 ENSMUST00000112859.1
ENSMUST00000137224.1
ENSMUST00000164472.1
ENSMUST00000112861.1
ENSMUST00000035638.8
zinc finger protein 637
chr2_-_84650760 0.03 ENSMUST00000111691.1
catenin (cadherin associated protein), delta 1
chr17_-_66594592 0.02 ENSMUST00000024914.2
thymocyte selection associated family member 3
chr2_-_84650714 0.01 ENSMUST00000111697.2
ENSMUST00000111670.2
ENSMUST00000111696.1
ENSMUST00000111678.1
ENSMUST00000111690.1
ENSMUST00000111695.1
ENSMUST00000111677.1
ENSMUST00000111698.1
ENSMUST00000099941.2
ENSMUST00000111676.1
ENSMUST00000111694.1
ENSMUST00000111675.1
ENSMUST00000111689.1
ENSMUST00000111687.1
ENSMUST00000111692.1
ENSMUST00000111685.1
ENSMUST00000111686.1
ENSMUST00000111688.1
ENSMUST00000111693.1
ENSMUST00000111684.1
catenin (cadherin associated protein), delta 1
chr2_+_34406845 0.01 ENSMUST00000124443.1
ENSMUST00000113124.1
mitogen-activated protein kinase associated protein 1
chr4_-_131937165 0.00 ENSMUST00000155990.1
erythrocyte protein band 4.1

Network of associatons between targets according to the STRING database.

First level regulatory network of Sox1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0015827 aromatic amino acid transport(GO:0015801) tryptophan transport(GO:0015827)
0.1 0.4 GO:0002343 peripheral B cell selection(GO:0002343) B cell affinity maturation(GO:0002344)
0.1 0.4 GO:0043323 positive regulation of natural killer cell degranulation(GO:0043323)
0.1 0.4 GO:0072675 osteoclast fusion(GO:0072675)
0.1 0.2 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.0 0.3 GO:0019348 dolichol metabolic process(GO:0019348)
0.0 0.4 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.2 GO:1902477 defense response to bacterium, incompatible interaction(GO:0009816) regulation of defense response to bacterium, incompatible interaction(GO:1902477)
0.0 0.1 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.0 0.2 GO:0060585 regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.0 0.2 GO:0032227 negative regulation of synaptic transmission, dopaminergic(GO:0032227)
0.0 0.4 GO:0006707 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.2 GO:0060139 positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation of apoptotic process by virus(GO:0060139)
0.0 0.3 GO:0015747 urate transport(GO:0015747)
0.0 0.3 GO:0030397 membrane disassembly(GO:0030397) nuclear envelope disassembly(GO:0051081)
0.0 0.1 GO:0002304 gamma-delta intraepithelial T cell differentiation(GO:0002304) CD8-positive, gamma-delta intraepithelial T cell differentiation(GO:0002305)
0.0 0.3 GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.0 0.1 GO:0045916 negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0044194 cytolytic granule(GO:0044194)
0.1 0.7 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.3 GO:0060053 neurofilament cytoskeleton(GO:0060053)
0.0 0.2 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.0 0.2 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.1 GO:0000813 ESCRT I complex(GO:0000813)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0033765 steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765)
0.1 0.6 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.1 0.3 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.1 0.4 GO:0042296 ISG15 transferase activity(GO:0042296)
0.1 0.3 GO:0070012 oligopeptidase activity(GO:0070012)
0.0 0.2 GO:0031708 endothelin B receptor binding(GO:0031708)
0.0 0.4 GO:1990405 protein antigen binding(GO:1990405)
0.0 0.3 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 0.2 GO:0019957 C-C chemokine binding(GO:0019957)
0.0 0.1 GO:0046790 virion binding(GO:0046790)
0.0 0.2 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.1 GO:0016493 C-C chemokine receptor activity(GO:0016493)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.0 0.4 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.1 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.3 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein