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2D miR_HR1_12

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Results for CCCUGAG

Z-value: 1.36

Motif logo

miRNA associated with seed CCCUGAG

NamemiRBASE accession
MIMAT0000135
MIMAT0000136
MIMAT0000609
MIMAT0025111
MIMAT0025144

Activity profile of CCCUGAG motif

Sorted Z-values of CCCUGAG motif

Promoter Log-likelihood Transcript Gene Gene Info
chr19_-_10457447 4.54 ENSMUST00000171400.2
leucine rich repeat containing 10B
chr11_+_61022560 2.33 ENSMUST00000089184.4
potassium inwardly-rectifying channel, subfamily J, member 12
chr3_-_129332713 2.29 ENSMUST00000029658.7
glutamyl aminopeptidase
chr13_+_89540636 1.81 ENSMUST00000022108.7
hyaluronan and proteoglycan link protein 1
chr4_+_118527229 1.75 ENSMUST00000030261.5
RIKEN cDNA 2610528J11 gene
chr7_-_79848191 1.75 ENSMUST00000107392.1
alanyl (membrane) aminopeptidase
chr10_-_61147659 1.56 ENSMUST00000092498.5
ENSMUST00000137833.1
ENSMUST00000155919.1
sphingosine phosphate lyase 1
chr14_-_110755100 1.54 ENSMUST00000078386.2
SLIT and NTRK-like family, member 6
chr18_-_10706688 1.47 ENSMUST00000002549.7
ENSMUST00000117726.1
ENSMUST00000117828.1
abhydrolase domain containing 3
chr17_+_72918298 1.40 ENSMUST00000024857.6
limb-bud and heart
chr9_+_57589442 1.35 ENSMUST00000053230.6
unc-51-like kinase 3
chr11_+_120530688 1.21 ENSMUST00000026119.7
glucagon receptor
chr10_+_112271123 1.20 ENSMUST00000092175.2
potassium voltage gated channel, Shaw-related subfamily, member 2
chr10_+_117629493 1.19 ENSMUST00000020399.5
carboxypeptidase M
chr3_+_138065052 1.15 ENSMUST00000163080.2
RIKEN cDNA 1110002E22 gene
chr2_+_130295148 1.13 ENSMUST00000110288.2
early B cell factor 4
chr11_+_43528759 1.12 ENSMUST00000050574.6
cyclin J-like
chr9_-_62537036 1.10 ENSMUST00000048043.5
coronin, actin binding protein, 2B
chr3_+_3508024 1.08 ENSMUST00000108393.1
ENSMUST00000017832.8
hepatocyte nuclear factor 4, gamma
chr3_+_27371351 1.05 ENSMUST00000057186.1
growth hormone secretagogue receptor
chr17_+_34931253 1.05 ENSMUST00000007253.5
neuraminidase 1
chr9_+_61372359 1.03 ENSMUST00000178113.1
ENSMUST00000159386.1
transducin-like enhancer of split 3, homolog of Drosophila E(spl)
chr6_-_72617000 1.03 ENSMUST00000070524.4
trans-golgi network protein
chr4_+_137862237 1.03 ENSMUST00000102518.3
endothelin converting enzyme 1
chr5_+_140607334 1.02 ENSMUST00000031555.1
LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr19_-_42752710 1.01 ENSMUST00000076505.3
pyridine nucleotide-disulphide oxidoreductase domain 2
chr14_+_30715599 0.96 ENSMUST00000054230.4
Scm-like with four mbt domains 1
chr19_-_17356631 0.95 ENSMUST00000174236.1
glucosaminyl (N-acetyl) transferase 1, core 2
chr17_+_35126316 0.94 ENSMUST00000061859.6
DNA segment, Chr 17, human D6S53E
chr12_-_78983476 0.94 ENSMUST00000070174.7
transmembrane protein 229B
chr5_-_34187670 0.92 ENSMUST00000042701.6
ENSMUST00000119171.1
Max dimerization protein 4
chr6_-_100287441 0.90 ENSMUST00000101118.2
RING1 and YY1 binding protein
chr3_-_27710413 0.89 ENSMUST00000046157.4
fibronectin type III domain containing 3B
chr6_+_122308684 0.85 ENSMUST00000007602.8
ENSMUST00000112610.1
mannose-6-phosphate receptor, cation dependent
chr12_+_80644212 0.84 ENSMUST00000085245.5
solute carrier family 39 (zinc transporter), member 9
chr12_-_83597140 0.84 ENSMUST00000048319.4
zinc finger, FYVE domain containing 1
chr11_+_95009852 0.84 ENSMUST00000055947.3
sterile alpha motif domain containing 14
chr5_-_147894804 0.83 ENSMUST00000118527.1
ENSMUST00000031655.3
ENSMUST00000138244.1
solute carrier family 46, member 3
chr17_-_56717681 0.79 ENSMUST00000164907.1
vimentin-type intermediate filament associated coiled-coil protein
chr4_-_118291340 0.79 ENSMUST00000049074.6
protein tyrosine phosphatase, receptor type, F
chr7_-_100371889 0.78 ENSMUST00000032963.8
protein phosphatase methylesterase 1
chr17_-_35188427 0.78 ENSMUST00000097336.4
leukocyte specific transcript 1
chr3_-_107518001 0.78 ENSMUST00000169449.1
ENSMUST00000029499.8
solute carrier family 6 (neurotransmitter transporter), member 17
chr11_-_100939357 0.78 ENSMUST00000092671.5
ENSMUST00000103114.1
signal transducer and activator of transcription 3
chr10_-_128525859 0.77 ENSMUST00000026427.6
extended synaptotagmin-like protein 1
chr11_-_106160101 0.77 ENSMUST00000045923.3
LIM domain containing 2
chr4_-_126533472 0.77 ENSMUST00000084289.4
argonaute RISC catalytic subunit 4
chrX_-_36645359 0.76 ENSMUST00000051906.6
A kinase (PRKA) anchor protein 17B
chr4_-_129227883 0.76 ENSMUST00000106051.1
expressed sequence C77080
chr12_+_71831064 0.76 ENSMUST00000085299.2
dishevelled associated activator of morphogenesis 1
chr15_-_71727815 0.75 ENSMUST00000022953.8
family with sequence similarity 135, member B
chr6_-_53820764 0.75 ENSMUST00000127748.2
TLR4 interactor with leucine-rich repeats
chr3_+_28781305 0.74 ENSMUST00000060500.7
eukaryotic translation initiation factor 5A2
chr2_+_91457501 0.73 ENSMUST00000028689.3
low density lipoprotein receptor-related protein 4
chr17_-_56218881 0.73 ENSMUST00000038794.4
dipeptidylpeptidase 9
chr7_+_80343091 0.73 ENSMUST00000032747.5
HD domain containing 3
chr6_+_108828633 0.72 ENSMUST00000089162.3
ER degradation enhancer, mannosidase alpha-like 1
chr3_+_108284089 0.71 ENSMUST00000102632.4
sortilin 1
chr1_-_106796687 0.70 ENSMUST00000094646.5
vacuolar protein sorting 4b (yeast)
chr2_-_118549668 0.70 ENSMUST00000090219.6
BCL2 modifying factor
chr15_+_99224976 0.70 ENSMUST00000041415.3
potassium voltage-gated channel, subfamily H (eag-related), member 3
chr8_-_70139197 0.70 ENSMUST00000075724.7
regulatory factor X-associated ankyrin-containing protein
chr5_-_113650390 0.69 ENSMUST00000047936.6
chemokine-like receptor 1
chr1_+_192190771 0.69 ENSMUST00000078470.5
ENSMUST00000110844.1
potassium voltage-gated channel, subfamily H (eag-related), member 1
chr11_+_75193783 0.68 ENSMUST00000102514.3
reticulon 4 receptor-like 1
chr6_-_31563978 0.67 ENSMUST00000026698.7
podocalyxin-like
chr6_-_126645784 0.67 ENSMUST00000055168.3
potassium voltage-gated channel, shaker-related subfamily, member 1
chr18_+_57354733 0.66 ENSMUST00000025490.8
proline-rich coiled-coil 1
chr16_-_20426375 0.66 ENSMUST00000079158.6
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
chr7_+_97081711 0.65 ENSMUST00000004622.5
growth factor receptor bound protein 2-associated protein 2
chr18_-_38211957 0.65 ENSMUST00000159405.1
ENSMUST00000160721.1
protocadherin 1
chr15_-_78120011 0.65 ENSMUST00000019290.2
calcium channel, voltage-dependent, gamma subunit 2
chr19_+_53677286 0.64 ENSMUST00000095969.3
ENSMUST00000164202.1
RNA binding motif protein 20
chr10_-_105574435 0.64 ENSMUST00000061506.8
transmembrane and tetratricopeptide repeat containing 2
chr4_-_114908892 0.63 ENSMUST00000068654.3
forkhead box D2
chr2_+_113327711 0.63 ENSMUST00000099576.2
formin 1
chr1_+_167001417 0.62 ENSMUST00000165874.1
family with sequence similarity 78, member B
chr4_-_89311021 0.62 ENSMUST00000097981.4
cyclin-dependent kinase inhibitor 2B (p15, inhibits CDK4)
chr11_+_98836775 0.62 ENSMUST00000107479.2
Rap guanine nucleotide exchange factor (GEF)-like 1
chr8_+_114133557 0.61 ENSMUST00000073521.5
ENSMUST00000066514.6
nudix (nucleoside diphosphate linked moiety X)-type motif 7
chr11_-_101119814 0.60 ENSMUST00000107295.3
family with sequence similarity 134, member C
chr19_-_5912834 0.59 ENSMUST00000136983.1
D4, zinc and double PHD fingers family 2
chr12_-_91849081 0.58 ENSMUST00000167466.1
ENSMUST00000021347.5
ENSMUST00000178462.1
sel-1 suppressor of lin-12-like (C. elegans)
chr9_-_58313189 0.58 ENSMUST00000061799.8
lysyl oxidase-like 1
chr15_-_31367527 0.58 ENSMUST00000076942.4
ENSMUST00000123325.1
ENSMUST00000110410.2
ankyrin repeat domain 33B
chr1_+_178319130 0.57 ENSMUST00000027781.6
COX20 Cox2 chaperone
chr13_+_31625802 0.57 ENSMUST00000042054.2
forkhead box F2
chr3_+_106547693 0.57 ENSMUST00000117469.1
ENSMUST00000067630.6
ENSMUST00000134396.1
ENSMUST00000144746.1
ENSMUST00000121034.1
ENSMUST00000029507.6
ENSMUST00000132923.1
ENSMUST00000151465.1
DNA-damage regulated autophagy modulator 2
chr12_-_15816762 0.57 ENSMUST00000020922.7
tribbles homolog 2 (Drosophila)
chr12_-_84970814 0.56 ENSMUST00000165886.1
ENSMUST00000167448.1
ENSMUST00000043169.7
apoptosis resistant E3 ubiquitin protein ligase 1
chr8_-_84237042 0.56 ENSMUST00000039480.5
zinc finger SWIM-type containing 4
chr4_-_119173849 0.56 ENSMUST00000052715.4
ENSMUST00000179290.1
ENSMUST00000154226.1
zinc finger protein 691
chr11_-_102819114 0.56 ENSMUST00000068933.5
gap junction protein, gamma 1
chr13_+_55593135 0.55 ENSMUST00000109905.3
transmembrane emp24 protein transport domain containing 9
chr9_-_26806384 0.55 ENSMUST00000162702.1
ENSMUST00000040398.7
ENSMUST00000066560.6
galactosidase, beta 1-like 2
chr12_-_59061425 0.55 ENSMUST00000021380.8
trafficking protein particle complex 6B
chr15_-_89140664 0.54 ENSMUST00000088827.6
mitogen-activated protein kinase 12
chr4_+_42949814 0.54 ENSMUST00000037872.3
ENSMUST00000098112.2
DnaJ (Hsp40) homolog, subfamily B, member 5
chr5_-_38561658 0.53 ENSMUST00000005234.9
WD repeat domain 1
chr7_+_97332311 0.53 ENSMUST00000054107.5
potassium channel tetramerisation domain containing 21
chr6_+_118066356 0.52 ENSMUST00000164960.1
RasGEF domain family, member 1A
chr7_-_19562377 0.52 ENSMUST00000058444.8
protein phosphatase 1, regulatory subunit 37
chr19_+_23758819 0.52 ENSMUST00000025830.7
amyloid beta (A4) precursor protein binding, family A, member 1
chr9_+_59750876 0.50 ENSMUST00000136740.1
ENSMUST00000135298.1
ENSMUST00000128341.1
myosin IXa
chr8_+_35587780 0.50 ENSMUST00000037666.5
malignant fibrous histiocytoma amplified sequence 1
chr11_-_103697898 0.49 ENSMUST00000021329.7
golgi SNAP receptor complex member 2
chr1_+_75142775 0.49 ENSMUST00000097694.4
family with sequence similarity 134, member A
chr10_+_79927039 0.49 ENSMUST00000019708.5
ENSMUST00000105377.1
AT rich interactive domain 3A (BRIGHT-like)
chr5_-_124032214 0.49 ENSMUST00000040967.7
vacuolar protein sorting 37B (yeast)
chr8_-_41133697 0.49 ENSMUST00000155055.1
ENSMUST00000059115.6
ENSMUST00000145860.1
mitochondrial tumor suppressor 1
chr12_-_108894116 0.48 ENSMUST00000109848.3
tryptophanyl-tRNA synthetase
chr12_+_24831583 0.48 ENSMUST00000110942.3
ENSMUST00000078902.6
membrane bound O-acyltransferase domain containing 2
chr9_+_45117813 0.48 ENSMUST00000170998.1
ENSMUST00000093855.3
sodium channel, voltage-gated, type II, beta
chr5_+_143235143 0.47 ENSMUST00000077485.4
ENSMUST00000032591.8
zinc finger protein 12
chr6_-_118197732 0.46 ENSMUST00000032201.5
ENSMUST00000088790.3
ret proto-oncogene
chr12_+_80790532 0.46 ENSMUST00000068519.5
RIKEN cDNA 4933426M11 gene
chr13_-_41487306 0.46 ENSMUST00000021794.6
neural precursor cell expressed, developmentally down-regulated gene 9
chr15_-_84447037 0.45 ENSMUST00000080751.2
RIKEN cDNA 1810041L15 gene
chr8_+_104101625 0.45 ENSMUST00000034339.8
cadherin 5
chrX_+_106920618 0.45 ENSMUST00000060576.7
lysophosphatidic acid receptor 4
chr1_-_40790642 0.45 ENSMUST00000039672.5
major facilitator superfamily domain containing 9
chr9_-_66919646 0.45 ENSMUST00000041139.7
RAB8B, member RAS oncogene family
chr15_+_95790831 0.45 ENSMUST00000071874.6
anoctamin 6
chr17_+_30901811 0.45 ENSMUST00000114574.1
glucagon-like peptide 1 receptor
chr11_+_69059750 0.44 ENSMUST00000051888.2
RIKEN cDNA 2310047M10 gene
chr11_+_102761402 0.43 ENSMUST00000103081.4
ENSMUST00000068150.5
a disintegrin and metallopeptidase domain 11
chr1_+_89070406 0.43 ENSMUST00000066279.4
SH3-domain binding protein 4
chr4_-_87230435 0.43 ENSMUST00000107157.2
solute carrier family 24 (sodium/potassium/calcium exchanger), member 2
chr19_-_6969746 0.43 ENSMUST00000025912.8
phospholipase C, beta 3
chr19_-_23448322 0.43 ENSMUST00000036069.6
MAM domain containing 2
chr13_-_59823072 0.43 ENSMUST00000071703.4
zinc finger, CCHC domain containing 6
chr2_-_12301914 0.43 ENSMUST00000028106.4
integrin alpha 8
chr11_-_51857624 0.42 ENSMUST00000020655.7
ENSMUST00000109090.1
PHD finger protein 15
chr5_-_151190154 0.42 ENSMUST00000062015.8
ENSMUST00000110483.2
StAR-related lipid transfer (START) domain containing 13
chr2_+_32876114 0.40 ENSMUST00000028135.8
family with sequence similarity 129, member B
chr4_-_46566432 0.40 ENSMUST00000030021.7
ENSMUST00000107757.1
coronin, actin binding protein 2A
chr17_+_73107982 0.40 ENSMUST00000130574.1
ENSMUST00000149064.1
ENSMUST00000067545.6
lysocardiolipin acyltransferase 1
chr6_-_21851914 0.40 ENSMUST00000134635.1
ENSMUST00000123116.1
ENSMUST00000120965.1
tetraspanin 12
chr9_+_108002501 0.39 ENSMUST00000035214.4
ENSMUST00000175874.1
inositol hexaphosphate kinase 1
chr19_+_40894692 0.39 ENSMUST00000050092.6
zinc finger protein 518A
chr14_-_118706180 0.39 ENSMUST00000036554.6
ENSMUST00000166646.1
ATP-binding cassette, sub-family C (CFTR/MRP), member 4
chr4_+_136310952 0.38 ENSMUST00000105850.1
ENSMUST00000148843.3
heterogeneous nuclear ribonucleoprotein R
chr14_-_40966807 0.38 ENSMUST00000047652.5
tetraspanin 14
chr6_+_83165920 0.38 ENSMUST00000077407.5
ENSMUST00000113913.1
ENSMUST00000130212.1
dynactin 1
chr1_+_191575721 0.38 ENSMUST00000045450.5
integrator complex subunit 7
chr14_+_31495065 0.37 ENSMUST00000022446.5
ELL associated factor 1
chr9_+_80165013 0.37 ENSMUST00000035889.8
ENSMUST00000113268.1
myosin VI
chr4_-_70534904 0.37 ENSMUST00000107359.2
multiple EGF-like-domains 9
chr5_-_67099235 0.37 ENSMUST00000012664.8
paired-like homeobox 2b
chr12_-_75177325 0.36 ENSMUST00000042299.2
potassium voltage-gated channel, subfamily H (eag-related), member 5
chr2_+_29802626 0.36 ENSMUST00000080065.2
solute carrier family 27 (fatty acid transporter), member 4
chr4_+_126753770 0.36 ENSMUST00000102607.3
ENSMUST00000047431.4
ENSMUST00000132660.1
expressed sequence AU040320
chr3_-_58692391 0.35 ENSMUST00000070368.7
seven in absentia 2
chr5_+_91517615 0.35 ENSMUST00000040576.9
prostate androgen-regulated mucin-like protein 1
chr5_+_77265454 0.35 ENSMUST00000080359.5
RE1-silencing transcription factor
chr5_-_125179155 0.35 ENSMUST00000111393.1
ENSMUST00000111394.1
ENSMUST00000111402.2
ENSMUST00000111398.1
nuclear receptor co-repressor 2
chr15_-_98763195 0.35 ENSMUST00000053183.9
ADP-ribosylation factor 3
chr1_-_157412576 0.35 ENSMUST00000078308.6
ENSMUST00000139470.1
RAS protein activator like 2
chr5_-_144965793 0.35 ENSMUST00000110677.1
ENSMUST00000085684.4
ENSMUST00000100461.2
SMAD specific E3 ubiquitin protein ligase 1
chr9_+_45138437 0.35 ENSMUST00000060125.5
sodium channel, type IV, beta
chr13_+_92611119 0.35 ENSMUST00000049488.7
serine incorporator 5
chr13_+_3634032 0.34 ENSMUST00000042288.6
ankyrin repeat and SOCS box-containing 13
chr7_+_27473761 0.34 ENSMUST00000068641.6
SERTA domain containing 3
chr8_+_4238733 0.34 ENSMUST00000110998.2
ENSMUST00000062686.4
mitogen-activated protein kinase kinase 7
chr2_+_38931975 0.34 ENSMUST00000057279.5
olfactomedin-like 2A
chr1_-_58586191 0.34 ENSMUST00000038372.7
ENSMUST00000097724.3
ENSMUST00000161000.1
ENSMUST00000161600.1
family with sequence similarity 126, member B
chr10_-_52382074 0.34 ENSMUST00000020008.8
ENSMUST00000105475.2
golgi associated PDZ and coiled-coil motif containing
chr10_+_42860348 0.33 ENSMUST00000063063.7
sex comb on midleg-like 4 (Drosophila)
chr6_-_82774448 0.33 ENSMUST00000000642.4
hexokinase 2
chr7_-_102065044 0.33 ENSMUST00000130074.1
ENSMUST00000131104.1
ENSMUST00000096639.5
ring finger protein 121
chr8_+_99416585 0.33 ENSMUST00000064349.5
RIKEN cDNA A330008L17 gene
chr11_-_60913775 0.32 ENSMUST00000019075.3
predicted gene, Gm16515
chr3_+_97901190 0.32 ENSMUST00000029476.2
ENSMUST00000122288.1
SEC22 vesicle trafficking protein homolog B (S. cerevisiae)
chr9_+_103112072 0.32 ENSMUST00000035155.6
RAB6B, member RAS oncogene family
chr14_+_65358661 0.32 ENSMUST00000066994.6
zinc finger protein 395
chr16_+_24393350 0.32 ENSMUST00000038053.6
LIM domain containing preferred translocation partner in lipoma
chr4_-_110287479 0.32 ENSMUST00000106598.1
ENSMUST00000102723.4
ENSMUST00000153906.1
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr18_-_66291770 0.31 ENSMUST00000130300.1
collagen and calcium binding EGF domains 1
chr9_+_58823512 0.31 ENSMUST00000034889.8
hyperpolarization-activated, cyclic nucleotide-gated K+ 4
chr3_+_88716838 0.31 ENSMUST00000029692.8
ENSMUST00000171645.1
Ras-like without CAAX 1
chr13_+_42301270 0.31 ENSMUST00000021796.7
endothelin 1
chr13_+_74350299 0.31 ENSMUST00000022063.7
coiled-coil domain containing 127
chr18_+_77185815 0.31 ENSMUST00000079618.4
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5
chr17_+_46161021 0.30 ENSMUST00000024748.7
ENSMUST00000172170.1
GTP binding protein 2
chr1_-_184999549 0.30 ENSMUST00000027929.4
MAP/microtubule affinity-regulating kinase 1
chr2_-_181599128 0.30 ENSMUST00000060173.8
sterile alpha motif domain containing 10
chr16_+_17233560 0.30 ENSMUST00000090190.5
ENSMUST00000115698.2
hypermethylated in cancer 2
chr19_+_44562841 0.30 ENSMUST00000040455.4
hypoxia-inducible factor 1, alpha subunit inhibitor
chr3_+_142530329 0.30 ENSMUST00000171263.1
ENSMUST00000045097.9
guanylate binding protein 7
chr17_-_73710415 0.30 ENSMUST00000112591.2
ENSMUST00000024858.5
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 14
chr16_+_5050012 0.29 ENSMUST00000052449.5
ubinuclein 1
chr10_-_8886033 0.29 ENSMUST00000015449.5
SAM and SH3 domain containing 1
chr2_+_152081529 0.28 ENSMUST00000064061.3
scratch homolog 2, zinc finger protein (Drosophila)
chr11_+_95712673 0.28 ENSMUST00000107717.1
zinc finger protein 652
chr12_+_32378692 0.28 ENSMUST00000172332.2
coiled-coil domain containing 71 like
chr4_-_119492563 0.28 ENSMUST00000049994.7
ribosomal modification protein rimK-like family member A
chr3_+_141465564 0.28 ENSMUST00000106236.2
ENSMUST00000075282.3
unc-5 homolog C (C. elegans)
chr11_-_90002881 0.27 ENSMUST00000020864.8
phosphatidylcholine transfer protein
chr11_-_4594750 0.27 ENSMUST00000109943.3
myotubularin related protein 3
chr15_+_76671615 0.27 ENSMUST00000037551.8
protein phosphatase 1, regulatory (inhibitor) subunit 16A

Network of associatons between targets according to the STRING database.

First level regulatory network of CCCUGAG

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0060005 vestibular reflex(GO:0060005)
0.5 2.3 GO:0002003 angiotensin maturation(GO:0002003)
0.4 1.1 GO:0043134 positive regulation of response to food(GO:0032097) positive regulation of appetite(GO:0032100) hindgut contraction(GO:0043133) regulation of hindgut contraction(GO:0043134) positive regulation of eating behavior(GO:1904000) positive regulation of small intestine smooth muscle contraction(GO:1904349)
0.3 1.0 GO:0010814 substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.3 1.8 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.2 0.7 GO:1904154 positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
0.2 0.7 GO:1903722 regulation of centriole elongation(GO:1903722)
0.2 0.7 GO:0050975 sensory perception of touch(GO:0050975)
0.2 1.0 GO:0007386 compartment pattern specification(GO:0007386)
0.2 0.8 GO:1902728 positive regulation of skeletal muscle satellite cell proliferation(GO:1902724) positive regulation of growth factor dependent skeletal muscle satellite cell proliferation(GO:1902728)
0.2 0.6 GO:0035964 COPI-coated vesicle budding(GO:0035964)
0.2 0.7 GO:1904395 positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395)
0.2 1.4 GO:1904672 regulation of somatic stem cell population maintenance(GO:1904672)
0.2 0.5 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.2 0.5 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.2 0.8 GO:0015803 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
0.2 0.5 GO:0035799 ureter maturation(GO:0035799)
0.2 0.6 GO:0033869 coenzyme A catabolic process(GO:0015938) nucleoside bisphosphate catabolic process(GO:0033869) ribonucleoside bisphosphate catabolic process(GO:0034031) purine nucleoside bisphosphate catabolic process(GO:0034034) acetyl-CoA catabolic process(GO:0046356)
0.1 1.0 GO:0006689 ganglioside catabolic process(GO:0006689) oligosaccharide catabolic process(GO:0009313)
0.1 0.4 GO:0070782 phosphatidylserine exposure on apoptotic cell surface(GO:0070782)
0.1 0.7 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.1 0.8 GO:0033762 response to glucagon(GO:0033762)
0.1 0.6 GO:0086053 AV node cell to bundle of His cell communication by electrical coupling(GO:0086053)
0.1 0.5 GO:0030043 actin filament fragmentation(GO:0030043)
0.1 0.8 GO:0051387 negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.1 0.7 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.1 0.4 GO:0021934 hindbrain tangential cell migration(GO:0021934)
0.1 0.3 GO:0071211 protein targeting to vacuole involved in autophagy(GO:0071211)
0.1 0.3 GO:0010360 negative regulation of anion channel activity(GO:0010360)
0.1 1.8 GO:0035814 negative regulation of renal sodium excretion(GO:0035814)
0.1 0.4 GO:0031161 phosphatidylinositol catabolic process(GO:0031161)
0.1 0.4 GO:2000721 positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721)
0.1 0.4 GO:0097498 endothelial tube lumen extension(GO:0097498)
0.1 1.6 GO:0030149 sphingolipid catabolic process(GO:0030149)
0.1 0.3 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.1 1.2 GO:1903818 positive regulation of voltage-gated potassium channel activity(GO:1903818)
0.1 0.3 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.1 0.5 GO:0046684 response to pyrethroid(GO:0046684)
0.1 0.1 GO:2000049 positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
0.1 0.4 GO:2000705 regulation of dense core granule biogenesis(GO:2000705)
0.1 0.3 GO:0072365 regulation of cellular ketone metabolic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072365)
0.1 0.5 GO:0072092 ureteric bud invasion(GO:0072092)
0.1 0.3 GO:1901526 positive regulation of macromitophagy(GO:1901526) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925)
0.1 0.3 GO:1901492 positive regulation of lymphangiogenesis(GO:1901492)
0.1 0.3 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.1 0.3 GO:0060585 regulation of prostaglandin-endoperoxide synthase activity(GO:0060584) positive regulation of prostaglandin-endoperoxide synthase activity(GO:0060585)
0.1 0.4 GO:0090063 positive regulation of microtubule nucleation(GO:0090063)
0.1 0.3 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.1 0.6 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.1 0.9 GO:0033299 secretion of lysosomal enzymes(GO:0033299)
0.1 0.2 GO:1902630 regulation of membrane hyperpolarization(GO:1902630)
0.1 0.3 GO:0009597 detection of virus(GO:0009597)
0.1 1.0 GO:0006895 Golgi to endosome transport(GO:0006895)
0.1 1.0 GO:0060352 cell adhesion molecule production(GO:0060352)
0.1 0.7 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.1 0.5 GO:1901552 blood vessel maturation(GO:0001955) positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.1 0.2 GO:0042663 regulation of endodermal cell fate specification(GO:0042663)
0.1 0.8 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.1 0.2 GO:0097155 fasciculation of sensory neuron axon(GO:0097155)
0.1 0.2 GO:1990743 protein sialylation(GO:1990743)
0.1 0.4 GO:0045046 peroxisomal membrane transport(GO:0015919) protein import into peroxisome membrane(GO:0045046)
0.1 0.1 GO:1904380 trimming of terminal mannose on B branch(GO:0036509) endoplasmic reticulum mannose trimming(GO:1904380)
0.1 0.2 GO:0070429 regulation of granuloma formation(GO:0002631) negative regulation of granuloma formation(GO:0002632) regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429) tolerance induction to lipopolysaccharide(GO:0072573)
0.1 0.2 GO:0045897 regulation of transcription during mitosis(GO:0045896) positive regulation of transcription during mitosis(GO:0045897)
0.1 0.2 GO:0002182 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
0.1 0.3 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.0 0.2 GO:1904953 Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation(GO:1904953)
0.0 0.3 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.0 0.2 GO:1903898 regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202) negative regulation of PERK-mediated unfolded protein response(GO:1903898)
0.0 0.2 GO:0072602 interleukin-4 secretion(GO:0072602)
0.0 0.2 GO:0010980 regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980) bile acid signaling pathway(GO:0038183)
0.0 0.5 GO:0060253 negative regulation of glial cell proliferation(GO:0060253)
0.0 0.7 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
0.0 0.7 GO:0060510 Type II pneumocyte differentiation(GO:0060510)
0.0 0.1 GO:0034224 cellular response to zinc ion starvation(GO:0034224)
0.0 0.4 GO:0042760 very long-chain fatty acid catabolic process(GO:0042760)
0.0 0.5 GO:0048681 negative regulation of axon regeneration(GO:0048681)
0.0 0.4 GO:0006020 inositol metabolic process(GO:0006020)
0.0 0.1 GO:0010536 positive regulation of activation of Janus kinase activity(GO:0010536)
0.0 0.4 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 1.4 GO:0010107 potassium ion import(GO:0010107)
0.0 0.2 GO:0006543 glutamine catabolic process(GO:0006543)
0.0 1.3 GO:0045879 negative regulation of smoothened signaling pathway(GO:0045879)
0.0 0.2 GO:0060011 Sertoli cell proliferation(GO:0060011)
0.0 0.2 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.0 0.1 GO:0060031 mediolateral intercalation(GO:0060031) planar cell polarity pathway involved in gastrula mediolateral intercalation(GO:0060775)
0.0 0.6 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 1.2 GO:0010758 regulation of macrophage chemotaxis(GO:0010758)
0.0 0.9 GO:0035518 histone H2A monoubiquitination(GO:0035518)
0.0 0.6 GO:0032693 negative regulation of interleukin-10 production(GO:0032693)
0.0 0.6 GO:0015812 gamma-aminobutyric acid secretion(GO:0014051) gamma-aminobutyric acid transport(GO:0015812)
0.0 0.8 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.0 0.3 GO:0032049 cardiolipin biosynthetic process(GO:0032049)
0.0 0.7 GO:0043306 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.0 0.4 GO:0071257 cellular response to electrical stimulus(GO:0071257)
0.0 0.1 GO:0045869 negative regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045869)
0.0 0.1 GO:0033078 extrathymic T cell differentiation(GO:0033078)
0.0 0.1 GO:0051684 maintenance of Golgi location(GO:0051684)
0.0 0.4 GO:0032310 prostaglandin secretion(GO:0032310)
0.0 0.1 GO:0090285 negative regulation of protein glycosylation in Golgi(GO:0090285)
0.0 0.7 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.1 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
0.0 0.4 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.0 0.1 GO:0044821 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.0 0.2 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0 0.1 GO:0060596 mammary placode formation(GO:0060596)
0.0 0.1 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
0.0 0.8 GO:0034142 toll-like receptor 4 signaling pathway(GO:0034142)
0.0 0.8 GO:0006829 zinc II ion transport(GO:0006829)
0.0 0.1 GO:0055099 response to high density lipoprotein particle(GO:0055099)
0.0 0.3 GO:0032274 gonadotropin secretion(GO:0032274)
0.0 0.1 GO:1903070 positive regulation of protein lipidation(GO:1903061) negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.0 0.4 GO:0061462 protein localization to lysosome(GO:0061462)
0.0 0.1 GO:1904996 positive regulation of leukocyte adhesion to vascular endothelial cell(GO:1904996)
0.0 0.9 GO:0046470 phosphatidylcholine metabolic process(GO:0046470)
0.0 0.1 GO:0021960 anterior commissure morphogenesis(GO:0021960)
0.0 0.2 GO:0060307 regulation of ventricular cardiac muscle cell membrane repolarization(GO:0060307)
0.0 0.8 GO:0006482 protein demethylation(GO:0006482) protein dealkylation(GO:0008214)
0.0 0.3 GO:0044406 adhesion of symbiont to host(GO:0044406)
0.0 0.7 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.1 GO:0035627 ER to Golgi ceramide transport(GO:0035621) ceramide transport(GO:0035627)
0.0 0.8 GO:0007257 activation of JUN kinase activity(GO:0007257)
0.0 0.1 GO:1902035 positive regulation of hematopoietic stem cell proliferation(GO:1902035)
0.0 0.5 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.0 0.3 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.2 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.0 0.2 GO:2000576 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 0.5 GO:0010842 retina layer formation(GO:0010842)
0.0 0.1 GO:0036315 cellular response to sterol(GO:0036315)
0.0 0.4 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.0 0.6 GO:0033120 positive regulation of RNA splicing(GO:0033120)
0.0 0.4 GO:0045823 positive regulation of heart contraction(GO:0045823)
0.0 0.4 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.0 1.2 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.2 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.0 0.2 GO:0048733 sebaceous gland development(GO:0048733)
0.0 0.2 GO:0051601 exocyst localization(GO:0051601)
0.0 0.1 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.0 0.1 GO:0045603 positive regulation of endothelial cell differentiation(GO:0045603)
0.0 0.6 GO:0045494 photoreceptor cell maintenance(GO:0045494)
0.0 0.1 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.0 0.2 GO:0051044 positive regulation of membrane protein ectodomain proteolysis(GO:0051044)
0.0 0.4 GO:0048596 embryonic camera-type eye morphogenesis(GO:0048596)
0.0 0.2 GO:0010172 embryonic body morphogenesis(GO:0010172)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 4.0 GO:0031983 vesicle lumen(GO:0031983)
0.3 0.8 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
0.1 1.3 GO:0033093 Weibel-Palade body(GO:0033093)
0.1 0.4 GO:0031088 platelet dense granule membrane(GO:0031088)
0.1 0.4 GO:0032783 ELL-EAF complex(GO:0032783)
0.1 0.6 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.1 0.8 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.1 0.3 GO:0098855 HCN channel complex(GO:0098855)
0.1 0.8 GO:0045098 type III intermediate filament(GO:0045098)
0.1 2.1 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.1 0.7 GO:0016600 flotillin complex(GO:0016600)
0.1 0.8 GO:0044232 organelle membrane contact site(GO:0044232)
0.1 0.5 GO:0000813 ESCRT I complex(GO:0000813)
0.1 0.6 GO:0098839 postsynaptic density membrane(GO:0098839)
0.0 0.1 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 0.4 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.5 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.6 GO:0090543 Flemming body(GO:0090543)
0.0 0.8 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.7 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 1.4 GO:0030904 retromer complex(GO:0030904)
0.0 0.8 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 0.4 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.0 0.1 GO:0034657 GID complex(GO:0034657)
0.0 0.5 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.7 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.2 GO:0071986 Ragulator complex(GO:0071986)
0.0 0.1 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 0.2 GO:1990909 Wnt signalosome(GO:1990909)
0.0 0.2 GO:0097443 sorting endosome(GO:0097443)
0.0 0.4 GO:0051286 cell tip(GO:0051286)
0.0 0.2 GO:0001651 dense fibrillar component(GO:0001651)
0.0 0.3 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.3 GO:0020005 symbiont-containing vacuole membrane(GO:0020005)
0.0 0.9 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 0.2 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 0.4 GO:0032039 integrator complex(GO:0032039)
0.0 0.2 GO:0070578 RISC-loading complex(GO:0070578)
0.0 2.2 GO:0030315 T-tubule(GO:0030315)
0.0 0.3 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.6 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.1 GO:0005927 muscle tendon junction(GO:0005927)
0.0 0.4 GO:0005922 connexon complex(GO:0005922)
0.0 0.6 GO:0090544 BAF-type complex(GO:0090544)
0.0 0.7 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.7 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.4 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.0 0.7 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 1.4 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 0.1 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.0 0.6 GO:0001917 photoreceptor inner segment(GO:0001917)
0.0 0.1 GO:0032584 growth cone membrane(GO:0032584)
0.0 0.2 GO:0000145 exocyst(GO:0000145)
0.0 0.3 GO:0042588 zymogen granule(GO:0042588)
0.0 0.6 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0004967 glucagon receptor activity(GO:0004967)
0.5 1.5 GO:0052739 phosphatidylserine 1-acylhydrolase activity(GO:0052739) 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.3 1.0 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.3 1.0 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.3 1.8 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.3 0.8 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.3 1.0 GO:0052796 exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997) exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.2 4.2 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.2 0.5 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.1 0.6 GO:0086077 gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling(GO:0086077)
0.1 0.7 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.1 0.6 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.1 0.7 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.1 0.8 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.1 0.6 GO:0004565 beta-galactosidase activity(GO:0004565)
0.1 1.2 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.1 0.4 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.1 1.6 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.1 0.8 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.1 1.6 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 0.4 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.1 0.3 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.1 0.7 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.1 0.4 GO:0000828 inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.1 0.8 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.1 0.3 GO:0031708 endothelin B receptor binding(GO:0031708)
0.1 0.3 GO:0005042 netrin receptor activity(GO:0005042)
0.1 0.3 GO:0008545 JUN kinase kinase activity(GO:0008545)
0.1 0.5 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.1 1.5 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.1 0.4 GO:0030911 TPR domain binding(GO:0030911)
0.1 0.2 GO:1902121 lithocholic acid binding(GO:1902121) D3 vitamins binding(GO:1902271)
0.1 0.2 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739)
0.1 0.3 GO:0071532 ankyrin repeat binding(GO:0071532)
0.1 0.7 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.8 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.2 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.0 0.3 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.7 GO:0019215 intermediate filament binding(GO:0019215)
0.0 0.3 GO:0008865 fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0 0.9 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.1 GO:0019981 interleukin-6 receptor activity(GO:0004915) interleukin-6 binding(GO:0019981)
0.0 0.4 GO:0015245 fatty acid transporter activity(GO:0015245)
0.0 0.9 GO:0005537 mannose binding(GO:0005537)
0.0 0.6 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.2 GO:0032450 maltose alpha-glucosidase activity(GO:0032450)
0.0 0.6 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.0 0.8 GO:0005328 neurotransmitter:sodium symporter activity(GO:0005328)
0.0 0.4 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.4 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.1 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.0 0.1 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.0 0.6 GO:0016641 oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor(GO:0016641)
0.0 0.5 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.6 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.7 GO:0004177 aminopeptidase activity(GO:0004177)
0.0 0.4 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.3 GO:0008525 phosphatidylcholine transporter activity(GO:0008525)
0.0 0.3 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.0 0.1 GO:0008142 oxysterol binding(GO:0008142)
0.0 0.1 GO:0004525 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.0 0.1 GO:0034711 inhibin binding(GO:0034711)
0.0 0.1 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.0 1.1 GO:0017046 peptide hormone binding(GO:0017046)
0.0 0.4 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.2 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.0 0.4 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 0.2 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.1 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.0 0.4 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.8 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.4 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.3 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.1 GO:0017040 ceramidase activity(GO:0017040)
0.0 1.6 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.3 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.1 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.0 0.6 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.0 0.2 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.3 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.1 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 2.4 GO:0051015 actin filament binding(GO:0051015)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.1 1.6 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 0.8 ST STAT3 PATHWAY STAT3 Pathway
0.0 0.5 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.9 PID E2F PATHWAY E2F transcription factor network
0.0 0.5 PID S1P S1P2 PATHWAY S1P2 pathway
0.0 0.4 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.2 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.4 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.5 PID ARF 3PATHWAY Arf1 pathway
0.0 0.7 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 1.0 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.2 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.3 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.7 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.3 PID ENDOTHELIN PATHWAY Endothelins
0.0 0.4 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.5 PID IL3 PATHWAY IL3-mediated signaling events
0.0 0.1 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 1.1 PID CXCR4 PATHWAY CXCR4-mediated signaling events
0.0 0.3 PID NETRIN PATHWAY Netrin-mediated signaling events
0.0 0.3 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.2 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.8 PID P75 NTR PATHWAY p75(NTR)-mediated signaling
0.0 0.8 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.2 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.4 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.1 0.8 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.1 1.4 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.1 0.8 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.1 1.5 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.1 0.2 REACTOME ENDOSOMAL VACUOLAR PATHWAY Genes involved in Endosomal/Vacuolar pathway
0.0 0.5 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.5 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.4 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.7 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 0.7 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.5 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 1.6 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.7 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 1.7 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors
0.0 0.4 REACTOME GAP JUNCTION TRAFFICKING Genes involved in Gap junction trafficking
0.0 1.1 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 1.0 REACTOME SPHINGOLIPID METABOLISM Genes involved in Sphingolipid metabolism
0.0 0.4 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.5 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 1.7 REACTOME TRANS GOLGI NETWORK VESICLE BUDDING Genes involved in trans-Golgi Network Vesicle Budding
0.0 1.3 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.5 REACTOME ACYL CHAIN REMODELLING OF PC Genes involved in Acyl chain remodelling of PC
0.0 0.6 REACTOME TRAFFICKING OF AMPA RECEPTORS Genes involved in Trafficking of AMPA receptors
0.0 1.4 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.5 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.2 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.3 REACTOME SIGNALLING TO P38 VIA RIT AND RIN Genes involved in Signalling to p38 via RIT and RIN
0.0 0.2 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.3 REACTOME REGULATION OF HYPOXIA INDUCIBLE FACTOR HIF BY OXYGEN Genes involved in Regulation of Hypoxia-inducible Factor (HIF) by Oxygen
0.0 0.5 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.2 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.7 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.4 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 0.3 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.3 REACTOME JNK C JUN KINASES PHOSPHORYLATION AND ACTIVATION MEDIATED BY ACTIVATED HUMAN TAK1 Genes involved in JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
0.0 0.3 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.5 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.4 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.1 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.3 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription