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2D miR_HR1_12

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Results for Isl2

Z-value: 0.82

Motif logo

Transcription factors associated with Isl2

Gene Symbol Gene ID Gene Info
ENSMUSG00000032318.6 insulin related protein 2 (islet 2)

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Isl2mm10_v2_chr9_+_55541148_55541209-0.441.5e-01Click!

Activity profile of Isl2 motif

Sorted Z-values of Isl2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chrX_+_164438039 2.09 ENSMUST00000033755.5
ankyrin repeat and SOCS box-containing 11
chr1_-_127840290 1.85 ENSMUST00000061512.2
mitogen-activated protein kinase kinase kinase 19
chr19_+_5474681 1.52 ENSMUST00000165485.1
ENSMUST00000166253.1
ENSMUST00000167371.1
ENSMUST00000167855.1
ENSMUST00000070118.7
epidermal growth factor-containing fibulin-like extracellular matrix protein 2
chr7_+_121083322 1.34 ENSMUST00000047025.8
ENSMUST00000170106.1
otoancorin
chr17_+_70561739 1.15 ENSMUST00000097288.2
discs, large (Drosophila) homolog-associated protein 1
chr17_+_17402672 0.98 ENSMUST00000115576.2
limb expression 1 homolog (chicken)
chr6_-_3399545 0.96 ENSMUST00000120087.3
sterile alpha motif domain containing 9-like
chr4_-_40722307 0.96 ENSMUST00000181475.1
predicted gene 6297
chr2_+_125136692 0.94 ENSMUST00000099452.2
cortexin 2
chr9_+_72958785 0.90 ENSMUST00000098567.2
ENSMUST00000034734.8
dyslexia susceptibility 1 candidate 1 homolog (human)
chr8_+_114133601 0.88 ENSMUST00000109109.1
nudix (nucleoside diphosphate linked moiety X)-type motif 7
chrX_-_139085230 0.85 ENSMUST00000152457.1
serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
chr4_+_110397661 0.83 ENSMUST00000106589.2
ENSMUST00000106587.2
ENSMUST00000106591.1
ENSMUST00000106592.1
ATP/GTP binding protein-like 4
chr4_+_102589687 0.80 ENSMUST00000097949.4
ENSMUST00000106901.1
phosphodiesterase 4B, cAMP specific
chr3_-_113574242 0.77 ENSMUST00000142505.2
amylase 1, salivary
chrX_-_139085211 0.76 ENSMUST00000033626.8
ENSMUST00000060824.3
serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
chr7_-_100656953 0.76 ENSMUST00000107046.1
ENSMUST00000107045.1
ENSMUST00000139708.1
pleckstrin homology domain containing, family B (evectins) member 1
chr4_-_42661893 0.75 ENSMUST00000108006.3
interleukin 11 receptor, alpha chain 2
chr8_+_114133635 0.75 ENSMUST00000147605.1
ENSMUST00000134593.1
nudix (nucleoside diphosphate linked moiety X)-type motif 7
chr11_+_5520652 0.75 ENSMUST00000063084.9
X-box binding protein 1
chr8_+_114133557 0.72 ENSMUST00000073521.5
ENSMUST00000066514.6
nudix (nucleoside diphosphate linked moiety X)-type motif 7
chr1_+_72284367 0.71 ENSMUST00000027380.5
ENSMUST00000141783.1
transmembrane protein 169
chr15_-_66560997 0.70 ENSMUST00000048372.5
transmembrane protein 71
chr4_-_111898695 0.69 ENSMUST00000102720.1
solute carrier family 5 (sodium/glucose cotransporter), member 9
chr9_-_119341390 0.66 ENSMUST00000139870.1
myeloid differentiation primary response gene 88
chr17_-_28560704 0.65 ENSMUST00000114785.1
ENSMUST00000025062.3
colipase, pancreatic
chr2_-_170602017 0.64 ENSMUST00000062355.1
RIKEN cDNA 4930470P17 gene
chr1_+_88211956 0.64 ENSMUST00000073049.6
UDP glucuronosyltransferase 1 family, polypeptide A1
chr10_+_75037066 0.63 ENSMUST00000147802.1
ENSMUST00000020391.5
RAB36, member RAS oncogene family
chr1_+_88055377 0.61 ENSMUST00000138182.1
ENSMUST00000113142.3
UDP glycosyltransferase 1 family, polypeptide A10
chr9_+_119102463 0.60 ENSMUST00000140326.1
ENSMUST00000165231.1
deleted in lung and esophageal cancer 1
chr11_-_80779989 0.58 ENSMUST00000041065.7
ENSMUST00000070997.5
myosin ID
chr10_+_69208546 0.55 ENSMUST00000164034.1
Rho-related BTB domain containing 1
chr6_-_83121385 0.53 ENSMUST00000146328.1
ENSMUST00000113936.3
ENSMUST00000032111.4
WW domain binding protein 1
chr2_+_69135799 0.53 ENSMUST00000041865.7
nitric oxide synthase trafficker
chr15_+_16778101 0.52 ENSMUST00000026432.6
cadherin 9
chr5_+_139378163 0.52 ENSMUST00000138631.1
ENSMUST00000053120.4
G protein-coupled receptor 146
RIKEN cDNA D830046C22 gene
chr10_+_116143881 0.51 ENSMUST00000105271.2
protein tyrosine phosphatase, receptor type, R
chr1_-_72874877 0.51 ENSMUST00000027377.8
insulin-like growth factor binding protein 5
chr4_+_3940747 0.51 ENSMUST00000119403.1
coiled-coil-helix-coiled-coil-helix domain containing 7
chr4_+_134102581 0.50 ENSMUST00000074690.4
ENSMUST00000070246.2
ENSMUST00000156750.1
UBX domain protein 11
chr1_+_156838915 0.49 ENSMUST00000111720.1
angiopoietin-like 1
chr13_+_67833235 0.48 ENSMUST00000060609.7
predicted gene 10037
chr10_+_75037291 0.48 ENSMUST00000139384.1
RAB36, member RAS oncogene family
chr6_-_136922169 0.47 ENSMUST00000032343.6
endoplasmic reticulum protein 27
chr19_+_45076105 0.47 ENSMUST00000026234.4
Kazal-type serine peptidase inhibitor domain 1
chr1_+_88055467 0.47 ENSMUST00000173325.1
UDP glycosyltransferase 1 family, polypeptide A10
chr5_+_66968559 0.46 ENSMUST00000127184.1
LIM and calponin homology domains 1
chr1_+_88070765 0.46 ENSMUST00000073772.4
UDP glucuronosyltransferase 1 family, polypeptide A9
chr12_+_109546409 0.45 ENSMUST00000143847.1
maternally expressed 3
chr5_+_66968961 0.45 ENSMUST00000132991.1
LIM and calponin homology domains 1
chr17_+_85028347 0.44 ENSMUST00000024944.7
solute carrier family 3, member 1
chr4_-_147642496 0.44 ENSMUST00000133006.1
ENSMUST00000037565.7
ENSMUST00000105720.1
RIKEN cDNA 2610305D13 gene
chr8_+_64947177 0.44 ENSMUST00000079896.7
ENSMUST00000026595.5
transmembrane protein 192
chr10_+_116966274 0.43 ENSMUST00000033651.3
RIKEN cDNA D630029K05 gene
chr2_+_22227503 0.41 ENSMUST00000044749.7
myosin IIIA
chr9_-_15301555 0.41 ENSMUST00000034414.8
RIKEN cDNA 4931406C07 gene
chr10_+_79996479 0.41 ENSMUST00000132517.1
ATP-binding cassette, sub-family A (ABC1), member 7
chr12_+_10390756 0.40 ENSMUST00000020947.5
retinol dehydrogenase 14 (all-trans and 9-cis)
chr3_-_75270073 0.39 ENSMUST00000039047.4
serine (or cysteine) peptidase inhibitor, clade I, member 2
chr6_+_78405148 0.39 ENSMUST00000023906.2
regenerating islet-derived 2
chr4_+_146161909 0.39 ENSMUST00000131932.1
zinc finger protein 600
chr16_-_48771956 0.39 ENSMUST00000170861.1
T cell receptor associated transmembrane adaptor 1
chr1_+_194619815 0.38 ENSMUST00000027952.5
plexin A2
chr4_+_147507600 0.38 ENSMUST00000063704.7
predicted gene 13152
chr15_+_84232030 0.38 ENSMUST00000023072.6
parvin, beta
chr4_-_94928820 0.37 ENSMUST00000107097.2
equatorin, sperm acrosome associated
chr9_+_108290433 0.36 ENSMUST00000035227.6
nicolin 1
chr3_-_67463828 0.36 ENSMUST00000058981.2
latexin
chr15_+_34453285 0.35 ENSMUST00000060894.7
cDNA sequence BC030476
chr8_+_25911670 0.34 ENSMUST00000120653.1
ENSMUST00000126226.1
potassium channel, subfamily U, member 1
chr6_-_115592571 0.34 ENSMUST00000112957.1
RIKEN cDNA 2510049J12 gene
chr13_-_12461432 0.33 ENSMUST00000143693.1
ENSMUST00000144283.1
ENSMUST00000099820.3
ENSMUST00000135166.1
lectin, galactose binding, soluble 8
chr5_+_90561102 0.33 ENSMUST00000094615.4
RIKEN cDNA 5830473C10 gene
chr4_+_147553277 0.33 ENSMUST00000139784.1
ENSMUST00000143885.1
ENSMUST00000081742.6
predicted gene 13154
chr1_+_46066738 0.33 ENSMUST00000069293.7
dynein, axonemal, heavy chain 7B
chr13_+_48513570 0.32 ENSMUST00000065465.1
RIKEN cDNA A830005F24 gene
chr1_-_121332571 0.31 ENSMUST00000071064.6
insulin induced gene 2
chr3_+_41742615 0.31 ENSMUST00000146165.1
ENSMUST00000119572.1
ENSMUST00000108065.2
ENSMUST00000120167.1
ENSMUST00000026867.7
ENSMUST00000026868.7
DNA segment, Chr 3, ERATO Doi 751, expressed
chrX_+_136245065 0.31 ENSMUST00000048687.4
WW domain binding protein 5
chr4_+_147492417 0.30 ENSMUST00000105721.2
predicted gene 13152
chr5_-_105051047 0.30 ENSMUST00000112718.4
guanylate-binding protein 8
chr11_-_49113757 0.29 ENSMUST00000060398.1
olfactory receptor 1396
chr8_+_121116163 0.29 ENSMUST00000054691.6
forkhead box C2
chr1_-_156034800 0.29 ENSMUST00000169241.1
torsin A interacting protein 1
chr11_+_83437678 0.28 ENSMUST00000037378.4
RIKEN cDNA 1700020L24 gene
chr4_-_94928789 0.28 ENSMUST00000030309.5
equatorin, sperm acrosome associated
chr17_-_56036546 0.28 ENSMUST00000003268.9
SH3-domain GRB2-like 1
chr9_-_113708209 0.27 ENSMUST00000111861.3
ENSMUST00000035086.6
programmed cell death 6 interacting protein
chr1_-_187215421 0.27 ENSMUST00000110945.3
ENSMUST00000183931.1
ENSMUST00000027908.6
spermatogenesis associated 17
chr10_-_109764840 0.26 ENSMUST00000163071.1
neuron navigator 3
chr6_-_42710036 0.26 ENSMUST00000045054.4
family with sequence similarity 115, member A
chr16_-_16829276 0.26 ENSMUST00000023468.5
sperm associated antigen 6
chr2_-_150255591 0.26 ENSMUST00000063463.5
predicted gene 21994
chr7_+_19119853 0.26 ENSMUST00000053109.3
F-box protein 46
chr14_+_27039001 0.26 ENSMUST00000035336.3
interleukin 17 receptor D
chrX_+_101383726 0.25 ENSMUST00000119190.1
gap junction protein, beta 1
chr7_-_6730412 0.25 ENSMUST00000051209.4
paternally expressed 3
chr17_+_66111529 0.25 ENSMUST00000072383.6
WAS protein family homolog
chr11_+_69838514 0.25 ENSMUST00000133967.1
ENSMUST00000094065.4
transmembrane protein 256
chr19_-_7966000 0.24 ENSMUST00000182102.1
ENSMUST00000075619.4
solute carrier family 22, member 27
chr4_-_147702553 0.24 ENSMUST00000117638.1
zinc finger protein 534
chrY_-_1245753 0.23 ENSMUST00000154004.1
ubiquitously transcribed tetratricopeptide repeat gene, Y chromosome
chr2_+_131491764 0.23 ENSMUST00000028806.5
ENSMUST00000110179.2
ENSMUST00000110189.2
ENSMUST00000110182.2
ENSMUST00000110183.2
ENSMUST00000110186.2
ENSMUST00000110188.1
spermine oxidase
chr7_-_126976092 0.23 ENSMUST00000181859.1
RIKEN cDNA D830044I16 gene
chr17_+_74489492 0.23 ENSMUST00000024873.6
Yip1 domain family, member 4
chr1_+_110099295 0.23 ENSMUST00000134301.1
cadherin 7, type 2
chr6_+_41302265 0.23 ENSMUST00000031913.4
trypsin 4
chr3_-_72967854 0.23 ENSMUST00000167334.1
sucrase isomaltase (alpha-glucosidase)
chr11_-_101278927 0.23 ENSMUST00000168089.1
ENSMUST00000017332.3
cytochrome C oxidase assembly factor 3
chr8_+_95703037 0.22 ENSMUST00000073139.7
ENSMUST00000080666.7
N-myc downstream regulated gene 4
chr9_+_119341294 0.22 ENSMUST00000039784.5
acetyl-Coenzyme A acyltransferase 1A
chr17_+_66111605 0.22 ENSMUST00000116556.2
WAS protein family homolog
chr4_-_86669492 0.22 ENSMUST00000149700.1
perilipin 2
chr17_+_26715644 0.22 ENSMUST00000062519.7
ENSMUST00000144221.1
ENSMUST00000142539.1
ENSMUST00000151681.1
CREB3 regulatory factor
chr4_+_146097312 0.22 ENSMUST00000105730.1
ENSMUST00000091878.5
predicted gene 13051
chr9_-_22117123 0.21 ENSMUST00000013966.6
elongation factor 1 homolog (ELF1, S. cerevisiae)
chr11_-_17953861 0.21 ENSMUST00000076661.6
Ewing's tumor-associated antigen 1
chr17_-_56005566 0.21 ENSMUST00000043785.6
signal transducing adaptor family member 2
chrX_-_75578188 0.21 ENSMUST00000033545.5
RAB39B, member RAS oncogene family
chr9_+_119341487 0.21 ENSMUST00000175743.1
ENSMUST00000176397.1
acetyl-Coenzyme A acyltransferase 1A
chr1_-_139858684 0.21 ENSMUST00000094489.3
complement factor H-related 2
chr5_-_118244861 0.21 ENSMUST00000117177.1
ENSMUST00000133372.1
ENSMUST00000154786.1
ENSMUST00000121369.1
ring finger protein, transmembrane 2
chr1_-_56969864 0.20 ENSMUST00000177424.1
special AT-rich sequence binding protein 2
chr13_-_67451585 0.20 ENSMUST00000057241.8
ENSMUST00000075255.5
zinc finger protein 874a
chr4_+_105157339 0.20 ENSMUST00000064139.7
phosphatidic acid phosphatase type 2B
chr12_-_84617326 0.20 ENSMUST00000021666.4
ATP-binding cassette, sub-family D (ALD), member 4
chr12_+_119443410 0.19 ENSMUST00000048880.6
metastasis associated in colon cancer 1
chrX_+_101449078 0.19 ENSMUST00000033674.5
integrin beta 1 binding protein 2
chr11_-_69237022 0.18 ENSMUST00000021259.2
ENSMUST00000108665.1
ENSMUST00000108664.1
guanylate cyclase 2e
chr11_-_98729374 0.18 ENSMUST00000126565.1
ENSMUST00000100500.2
ENSMUST00000017354.6
mediator complex subunit 24
chr14_-_64455903 0.18 ENSMUST00000067927.7
methionine sulfoxide reductase A
chr9_+_56418624 0.17 ENSMUST00000034879.3
high mobility group 20A
chr4_+_147021850 0.17 ENSMUST00000075775.5
reduced expression 2
chr11_+_94327984 0.17 ENSMUST00000107818.2
ENSMUST00000051221.6
ankyrin repeat domain 40
chr15_-_37459327 0.16 ENSMUST00000119730.1
ENSMUST00000120746.1
neurocalcin delta
chrX_-_150813637 0.16 ENSMUST00000112700.1
melanoma antigen, family D, 2
chr14_-_51195923 0.16 ENSMUST00000051274.1
angiogenin, ribonuclease A family, member 2
chr8_+_107031218 0.16 ENSMUST00000034388.9
vacuolar protein sorting 4a (yeast)
chr5_-_107875035 0.16 ENSMUST00000138111.1
ENSMUST00000112642.1
ecotropic viral integration site 5
chr10_+_101681487 0.15 ENSMUST00000179929.1
ENSMUST00000127504.1
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr9_-_102354685 0.15 ENSMUST00000035129.7
ENSMUST00000085169.5
Eph receptor B1
chr3_-_49757257 0.15 ENSMUST00000035931.7
protocadherin 18
chr2_+_62664279 0.14 ENSMUST00000028257.2
grancalcin
chr8_-_111338152 0.14 ENSMUST00000056157.7
ENSMUST00000120432.1
mixed lineage kinase domain-like
chr14_+_51129055 0.13 ENSMUST00000095923.3
ribonuclease, RNase A family, 6
chr6_+_65590382 0.13 ENSMUST00000114236.1
TNFAIP3 interacting protein 3
chr3_+_41563356 0.12 ENSMUST00000163764.1
PHD finger protein 17
chr1_+_190928492 0.11 ENSMUST00000066632.7
ENSMUST00000110899.1
angel homolog 2 (Drosophila)
chr1_+_44147847 0.11 ENSMUST00000027214.3
excision repair cross-complementing rodent repair deficiency, complementation group 5
chr3_+_103171655 0.11 ENSMUST00000005830.8
breast carcinoma amplified sequence 2
chrX_-_103981242 0.10 ENSMUST00000121153.1
ENSMUST00000070705.4
ring finger protein, LIM domain interacting
chr7_-_9953585 0.10 ENSMUST00000165611.1
vomeronasal 2, receptor 48
chr18_-_73754457 0.10 ENSMUST00000041138.2
elaC homolog 1 (E. coli)
chr10_-_85127977 0.10 ENSMUST00000050813.2
MTERF domain containing 3
chr10_-_61784014 0.10 ENSMUST00000020283.4
H2A histone family, member Y2
chr10_+_116964707 0.10 ENSMUST00000176050.1
ENSMUST00000176455.1
RIKEN cDNA D630029K05 gene
chr6_+_123262107 0.10 ENSMUST00000032240.2
C-type lectin domain family 4, member d
chr10_-_13324160 0.10 ENSMUST00000105545.4
phosphatase and actin regulator 2
chr9_-_7835255 0.10 ENSMUST00000074246.6
baculoviral IAP repeat-containing 2
chr13_-_105271039 0.09 ENSMUST00000069686.6
ring finger protein 180
chr3_-_67515487 0.09 ENSMUST00000178314.1
ENSMUST00000054825.4
retinoic acid receptor responder (tazarotene induced) 1
chr1_+_88306731 0.09 ENSMUST00000040210.7
transient receptor potential cation channel, subfamily M, member 8
chr5_-_69590783 0.09 ENSMUST00000173927.1
glucosamine-6-phosphate deaminase 2
chr8_-_9976294 0.09 ENSMUST00000095476.4
ligase IV, DNA, ATP-dependent
chr1_+_187215501 0.09 ENSMUST00000097443.3
ENSMUST00000065573.7
ENSMUST00000110943.2
ENSMUST00000044812.5
G patch domain containing 2
chr1_-_121332545 0.09 ENSMUST00000161068.1
insulin induced gene 2
chr4_-_88722454 0.08 ENSMUST00000094993.2
kelch-like 9
chrX_-_20931520 0.08 ENSMUST00000001156.7
complement factor properdin
chr10_+_102158858 0.08 ENSMUST00000138522.1
ENSMUST00000163753.1
ENSMUST00000138016.1
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr2_+_115581667 0.08 ENSMUST00000166472.1
ENSMUST00000110918.2
cDNA sequence BC052040
chr6_+_125049903 0.08 ENSMUST00000112413.1
proacrosin binding protein
chr6_-_129100903 0.08 ENSMUST00000032258.6
C-type lectin domain family 2, member e
chr4_+_146156824 0.08 ENSMUST00000168483.2
zinc finger protein 600
chr5_-_88675190 0.07 ENSMUST00000133532.1
ENSMUST00000150438.1
G-rich RNA sequence binding factor 1
chr1_-_187215454 0.07 ENSMUST00000183819.1
spermatogenesis associated 17
chr4_+_145510759 0.07 ENSMUST00000105742.1
ENSMUST00000136309.1
predicted gene 13225
chr9_-_40984460 0.07 ENSMUST00000180872.1
cytotoxic and regulatory T cell molecule
chr11_+_96286623 0.06 ENSMUST00000049352.7
homeobox B7
chr6_+_29859686 0.06 ENSMUST00000134438.1
S-adenosylhomocysteine hydrolase-like 2
chr5_-_3647806 0.06 ENSMUST00000119783.1
ENSMUST00000007559.8
GATA zinc finger domain containing 1
chr19_-_39740999 0.06 ENSMUST00000099472.3
cytochrome P450, family 2, subfamily c, polypeptide 68
chr11_+_58786139 0.06 ENSMUST00000076393.3
olfactory receptor 314
chr8_-_125492710 0.06 ENSMUST00000108775.1
signal-induced proliferation-associated 1 like 2
chr19_-_8131982 0.05 ENSMUST00000065651.4
solute carrier family 22, member 28
chr9_+_109816571 0.05 ENSMUST00000055821.5
serine peptidase inhibitor, Kazal type 8
chr4_+_139653538 0.05 ENSMUST00000030510.7
ENSMUST00000166773.1
taste receptor, type 1, member 2
chr16_+_11406618 0.04 ENSMUST00000122168.1
sorting nexin 29
chr10_-_127311740 0.04 ENSMUST00000037290.5
ENSMUST00000171564.1
methionine-tRNA synthetase
chr14_+_122034660 0.04 ENSMUST00000045976.6
translocase of inner mitochondrial membrane 8A2
chr3_-_62506970 0.04 ENSMUST00000029336.4
DEAH (Asp-Glu-Ala-His) box polypeptide 36
chr2_+_109917639 0.04 ENSMUST00000046548.7
ENSMUST00000111037.2
leucine-rich repeat-containing G protein-coupled receptor 4
chr2_+_157367594 0.04 ENSMUST00000081202.5
mannosidase, beta A, lysosomal-like
chr10_-_63927434 0.04 ENSMUST00000079279.3
predicted gene 10118
chr8_+_88118747 0.04 ENSMUST00000095214.3
CTD nuclear envelope phosphatase 1 regulatory subunit 1
chr4_-_14621805 0.03 ENSMUST00000042221.7
solute carrier family 26, member 7
chrX_+_164373363 0.03 ENSMUST00000033751.7
c-fos induced growth factor
chr5_+_105558858 0.03 ENSMUST00000153754.1
leucine rich repeat containing 8 family, member C
chr19_+_25406661 0.03 ENSMUST00000146647.1
KN motif and ankyrin repeat domains 1
chr4_-_14621494 0.02 ENSMUST00000149633.1
solute carrier family 26, member 7

Network of associatons between targets according to the STRING database.

First level regulatory network of Isl2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.4 GO:0033869 coenzyme A catabolic process(GO:0015938) nucleoside bisphosphate catabolic process(GO:0033869) ribonucleoside bisphosphate catabolic process(GO:0034031) purine nucleoside bisphosphate catabolic process(GO:0034034) acetyl-CoA catabolic process(GO:0046356)
0.5 1.6 GO:0033189 response to vitamin A(GO:0033189)
0.3 1.0 GO:0035470 positive regulation of vascular wound healing(GO:0035470)
0.2 0.8 GO:0035609 C-terminal protein deglutamylation(GO:0035609)
0.2 2.2 GO:0052697 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.2 0.7 GO:0072566 positive regulation of interleukin-23 production(GO:0032747) chemokine (C-X-C motif) ligand 1 production(GO:0072566) regulation of chemokine (C-X-C motif) ligand 1 production(GO:2000338)
0.1 1.1 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.1 0.4 GO:1901074 regulation of engulfment of apoptotic cell(GO:1901074)
0.1 0.7 GO:0060478 acrosomal vesicle exocytosis(GO:0060478)
0.1 0.5 GO:0014734 skeletal muscle hypertrophy(GO:0014734)
0.1 0.4 GO:0021934 hindbrain tangential cell migration(GO:0021934)
0.1 0.5 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.1 0.3 GO:0000912 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.1 1.2 GO:0070842 aggresome assembly(GO:0070842)
0.1 0.4 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.1 0.8 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1 0.3 GO:0002317 plasma cell differentiation(GO:0002317)
0.1 0.7 GO:1904659 glucose transmembrane transport(GO:1904659)
0.1 0.9 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 0.2 GO:0046208 spermine catabolic process(GO:0046208)
0.0 0.1 GO:0021631 optic nerve morphogenesis(GO:0021631)
0.0 0.1 GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.0 0.2 GO:1900170 prolactin signaling pathway(GO:0038161) negative regulation of glucocorticoid mediated signaling pathway(GO:1900170)
0.0 0.3 GO:0015747 urate transport(GO:0015747)
0.0 0.1 GO:1902524 positive regulation of protein K48-linked ubiquitination(GO:1902524) positive regulation of protein monoubiquitination(GO:1902527)
0.0 0.2 GO:0071557 histone H3-K27 demethylation(GO:0071557)
0.0 0.3 GO:0071763 nuclear membrane organization(GO:0071763)
0.0 0.2 GO:0009235 cobalamin metabolic process(GO:0009235)
0.0 1.0 GO:0097352 autophagosome maturation(GO:0097352)
0.0 0.4 GO:0060363 cranial suture morphogenesis(GO:0060363)
0.0 0.1 GO:0002355 detection of tumor cell(GO:0002355)
0.0 0.3 GO:0015868 purine ribonucleotide transport(GO:0015868)
0.0 0.3 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.0 0.1 GO:1900095 regulation of dosage compensation by inactivation of X chromosome(GO:1900095)
0.0 0.1 GO:0042780 tRNA 3'-end processing(GO:0042780)
0.0 0.2 GO:0070294 renal sodium ion absorption(GO:0070294)
0.0 0.1 GO:0038094 Fc-gamma receptor signaling pathway(GO:0038094)
0.0 0.4 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.0 0.5 GO:0008340 determination of adult lifespan(GO:0008340)
0.0 0.4 GO:0016048 detection of temperature stimulus(GO:0016048)
0.0 0.7 GO:0032094 response to food(GO:0032094)
0.0 0.4 GO:0042572 retinol metabolic process(GO:0042572)
0.0 0.2 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)
0.0 0.2 GO:2001135 regulation of endocytic recycling(GO:2001135)
0.0 0.1 GO:1901837 negative regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901837)
0.0 0.2 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.4 GO:0001967 suckling behavior(GO:0001967)
0.0 0.1 GO:0097680 double-strand break repair via classical nonhomologous end joining(GO:0097680)
0.0 0.2 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.0 0.0 GO:0071963 establishment or maintenance of cell polarity regulating cell shape(GO:0071963)
0.0 0.1 GO:0002756 MyD88-independent toll-like receptor signaling pathway(GO:0002756)
0.0 0.4 GO:0008206 bile acid metabolic process(GO:0008206)
0.0 0.0 GO:1900003 regulation of serine-type endopeptidase activity(GO:1900003) negative regulation of serine-type endopeptidase activity(GO:1900004) regulation of serine-type peptidase activity(GO:1902571) negative regulation of serine-type peptidase activity(GO:1902572)
0.0 0.0 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.0 0.2 GO:0033234 negative regulation of protein sumoylation(GO:0033234)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0002079 inner acrosomal membrane(GO:0002079) outer acrosomal membrane(GO:0002081)
0.1 0.5 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.1 0.4 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 0.6 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.8 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.4 GO:0090543 Flemming body(GO:0090543)
0.0 0.6 GO:0032433 filopodium tip(GO:0032433)
0.0 0.5 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.6 GO:0005790 smooth endoplasmic reticulum(GO:0005790)
0.0 0.1 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958) DNA ligase IV complex(GO:0032807)
0.0 0.1 GO:0001740 Barr body(GO:0001740)
0.0 0.4 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.3 GO:0005922 connexon complex(GO:0005922)
0.0 0.0 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.0 0.4 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.2 GO:0005662 DNA replication factor A complex(GO:0005662)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.4 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.2 0.7 GO:0070976 TIR domain binding(GO:0070976)
0.1 0.4 GO:0030226 apolipoprotein receptor activity(GO:0030226) apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.1 0.8 GO:0004556 alpha-amylase activity(GO:0004556)
0.1 0.3 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.1 0.4 GO:0008410 CoA-transferase activity(GO:0008410)
0.1 0.3 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.1 0.2 GO:0052901 polyamine oxidase activity(GO:0046592) spermine:oxygen oxidoreductase (spermidine-forming) activity(GO:0052901)
0.1 0.7 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.1 2.1 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.1 0.2 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.1 0.2 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.1 0.5 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.1 1.0 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.8 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0 0.2 GO:0071558 histone demethylase activity (H3-K27 specific)(GO:0071558)
0.0 0.3 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.1 GO:0098770 FBXO family protein binding(GO:0098770)
0.0 0.3 GO:1901702 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 0.2 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.4 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.7 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.4 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.8 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.4 GO:0008106 alcohol dehydrogenase (NADP+) activity(GO:0008106)
0.0 0.1 GO:0000405 bubble DNA binding(GO:0000405)
0.0 0.5 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 2.1 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.1 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.1 GO:0004342 glucosamine-6-phosphate deaminase activity(GO:0004342)
0.0 0.3 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.5 GO:0050699 WW domain binding(GO:0050699)
0.0 0.7 GO:0030331 estrogen receptor binding(GO:0030331)
0.0 0.3 GO:0005521 lamin binding(GO:0005521)
0.0 0.1 GO:0003909 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.7 PID HNF3A PATHWAY FOXA1 transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.1 0.8 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1 0.7 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.5 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.4 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.8 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.8 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.7 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0 0.4 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.5 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.0 0.3 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.4 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.2 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.2 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.4 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling