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2D miR_HR1_12

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Results for Hoxc10

Z-value: 0.41

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Transcription factors associated with Hoxc10

Gene Symbol Gene ID Gene Info
ENSMUSG00000022484.7 homeobox C10

Activity profile of Hoxc10 motif

Sorted Z-values of Hoxc10 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr7_-_30924169 0.41 ENSMUST00000074671.6
hepcidin antimicrobial peptide 2
chr2_+_163506808 0.37 ENSMUST00000143911.1
hepatic nuclear factor 4, alpha
chr7_-_73537621 0.33 ENSMUST00000172704.1
chromodomain helicase DNA binding protein 2
chr1_+_107511489 0.32 ENSMUST00000064916.2
serine (or cysteine) peptidase inhibitor, clade B, member 2
chr2_-_32387760 0.29 ENSMUST00000050785.8
lipocalin 2
chr14_-_37110087 0.27 ENSMUST00000179488.1
RIKEN cDNA 2610528A11 gene
chr1_+_66386968 0.24 ENSMUST00000145419.1
microtubule-associated protein 2
chr4_-_73790602 0.22 ENSMUST00000058292.6
ENSMUST00000102837.2
RAS and EF hand domain containing
chr1_+_159737510 0.19 ENSMUST00000111669.3
tenascin R
chr5_-_62765618 0.19 ENSMUST00000159470.1
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr2_-_25469742 0.17 ENSMUST00000114259.2
ENSMUST00000015234.6
prostaglandin D2 synthase (brain)
chr11_-_109472611 0.15 ENSMUST00000168740.1
solute carrier family 16 (monocarboxylic acid transporters), member 6
chr11_-_100146120 0.15 ENSMUST00000007317.7
keratin 19
chr14_+_13453937 0.14 ENSMUST00000153954.1
synaptoporin
chr4_-_137118135 0.13 ENSMUST00000154285.1
predicted gene 13001
chr10_+_88091070 0.13 ENSMUST00000048621.7
pro-melanin-concentrating hormone
chr2_-_25470031 0.13 ENSMUST00000114251.1
prostaglandin D2 synthase (brain)
chr1_+_191025350 0.13 ENSMUST00000181050.1
RIKEN cDNA A230020J21 gene
chr17_-_78684262 0.13 ENSMUST00000145480.1
striatin, calmodulin binding protein
chr1_-_144249134 0.13 ENSMUST00000172388.1
regulator of G-protein signaling 1
chr3_+_64081642 0.12 ENSMUST00000029406.4
vomeronasal 2, receptor 1
chr6_+_71199827 0.11 ENSMUST00000067492.7
fatty acid binding protein 1, liver
chr17_-_31144271 0.11 ENSMUST00000024826.7
trefoil factor 2 (spasmolytic protein 1)
chr2_-_129371131 0.10 ENSMUST00000028881.7
interleukin 1 beta
chr3_+_3634145 0.10 ENSMUST00000108394.1
hepatocyte nuclear factor 4, gamma
chr8_-_41016295 0.10 ENSMUST00000131965.1
mitochondrial tumor suppressor 1
chr9_+_50575273 0.10 ENSMUST00000059081.6
ENSMUST00000180021.1
interleukin 18
chr11_-_79504078 0.10 ENSMUST00000164465.2
oligodendrocyte myelin glycoprotein
chr1_-_97761538 0.09 ENSMUST00000171129.1
diphosphoinositol pentakisphosphate kinase 2
chr9_+_53771499 0.09 ENSMUST00000048670.8
solute carrier family 35, member F2
chr3_+_69222412 0.08 ENSMUST00000183126.1
ADP-ribosylation factor-like 14
chr1_+_60977898 0.08 ENSMUST00000027162.5
ENSMUST00000102827.3
inducible T cell co-stimulator
chr17_-_26199008 0.08 ENSMUST00000142410.1
ENSMUST00000120333.1
ENSMUST00000039113.7
protein disulfide isomerase associated 2
chr19_-_7341848 0.08 ENSMUST00000171393.1
MAP/microtubule affinity-regulating kinase 2
chr4_+_11758147 0.08 ENSMUST00000029871.5
ENSMUST00000108303.1
cadherin 17
chr15_+_81936753 0.07 ENSMUST00000038757.7
cold shock domain containing C2, RNA binding
chr10_+_52391606 0.07 ENSMUST00000067085.4
nephrocan
chr15_+_81936911 0.07 ENSMUST00000135663.1
cold shock domain containing C2, RNA binding
chr11_-_55607733 0.07 ENSMUST00000108853.1
ENSMUST00000075603.4
glycine receptor, alpha 1 subunit
chr9_-_37255730 0.07 ENSMUST00000115068.2
solute carrier family 37 (glycerol-3-phosphate transporter), member 2
chr3_-_63851251 0.07 ENSMUST00000162269.2
ENSMUST00000159676.2
ENSMUST00000175947.1
phospholipase C, eta 1
chr17_-_36190121 0.07 ENSMUST00000097329.3
ENSMUST00000025312.6
ENSMUST00000102675.3
histocompatibility 2, T region locus 3
chr3_-_88410295 0.07 ENSMUST00000056370.7
polyamine-modulated factor 1
chr13_-_18172540 0.07 ENSMUST00000184299.1
ENSMUST00000063256.5
POU domain, class 6, transcription factor 2
chr1_+_180111339 0.06 ENSMUST00000145181.1
CDC42 binding protein kinase alpha
chr1_+_63176818 0.06 ENSMUST00000129339.1
eukaryotic translation elongation factor 1 beta 2
chr1_-_86111970 0.06 ENSMUST00000027431.6
5-hydroxytryptamine (serotonin) receptor 2B
chr1_+_127729405 0.06 ENSMUST00000038006.6
amino carboxymuconate semialdehyde decarboxylase
chr1_-_149961230 0.05 ENSMUST00000070200.8
phospholipase A2, group IVA (cytosolic, calcium-dependent)
chr3_+_76074270 0.05 ENSMUST00000038364.8
follistatin-like 5
chr1_-_69108039 0.05 ENSMUST00000121473.1
v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)
chr2_+_80315461 0.05 ENSMUST00000028392.7
DnaJ (Hsp40) homolog, subfamily C, member 10
chrX_+_133908441 0.05 ENSMUST00000113304.1
sushi-repeat-containing protein, X-linked 2
chr8_-_111992258 0.05 ENSMUST00000034427.5
ENSMUST00000139820.1
adenosine deaminase, tRNA-specific 1
chr19_+_56548254 0.05 ENSMUST00000071423.5
NHL repeat containing 2
chr15_+_6422240 0.05 ENSMUST00000163082.1
disabled 2, mitogen-responsive phosphoprotein
chr1_-_63114255 0.04 ENSMUST00000153992.1
ENSMUST00000165066.1
ENSMUST00000172416.1
ENSMUST00000137511.1
INO80 complex subunit D
chr10_-_28986280 0.04 ENSMUST00000152363.1
ENSMUST00000015663.6
RIKEN cDNA 2310057J18 gene
chr15_+_16778101 0.04 ENSMUST00000026432.6
cadherin 9
chr4_+_144893127 0.04 ENSMUST00000142808.1
dehydrogenase/reductase (SDR family) member 3
chr12_+_59095653 0.04 ENSMUST00000021384.4
melanoma inhibitory activity 2
chr11_+_29463735 0.04 ENSMUST00000155854.1
coiled coil domain containing 88A
chrX_-_134541847 0.04 ENSMUST00000054213.4
translocase of inner mitochondrial membrane 8A1
chr17_-_90088343 0.04 ENSMUST00000173917.1
neurexin I
chr10_+_37139558 0.04 ENSMUST00000062667.3
RIKEN cDNA 5930403N24 gene
chr1_+_189728264 0.04 ENSMUST00000097442.2
protein tyrosine phosphatase, non-receptor type 14
chr15_+_100761741 0.04 ENSMUST00000023776.6
solute carrier family 4 (anion exchanger), member 8
chr3_-_146770218 0.03 ENSMUST00000106137.1
protein kinase, cAMP dependent, catalytic, beta
chr3_+_108591279 0.03 ENSMUST00000051145.8
ENSMUST00000139626.1
WD repeat domain 47
chr8_-_62123106 0.03 ENSMUST00000034052.6
ENSMUST00000034054.7
annexin A10
chr1_-_45503282 0.03 ENSMUST00000086430.4
collagen, type V, alpha 2
chr5_+_71699918 0.02 ENSMUST00000031122.7
gamma-aminobutyric acid (GABA) A receptor, subunit beta 1
chr1_+_179961110 0.02 ENSMUST00000076687.5
ENSMUST00000097450.3
CDC42 binding protein kinase alpha
chr1_-_63176653 0.02 ENSMUST00000027111.8
ENSMUST00000168099.2
NADH dehydrogenase (ubiquinone) Fe-S protein 1
chr5_-_62766153 0.02 ENSMUST00000076623.4
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr4_-_110290884 0.02 ENSMUST00000142722.1
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr10_-_49783259 0.02 ENSMUST00000105484.3
ENSMUST00000105486.1
ENSMUST00000079751.2
ENSMUST00000105485.1
glutamate receptor, ionotropic, kainate 2 (beta 2)
chr7_-_141435327 0.02 ENSMUST00000138865.1
solute carrier family 25 (mitochondrial carrier, glutamate), member 22
chr5_-_64932761 0.02 ENSMUST00000059349.4
toll-like receptor 1
chr19_-_50678642 0.02 ENSMUST00000072685.6
ENSMUST00000164039.2
VPS10 domain receptor protein SORCS 1
chr11_-_99993992 0.02 ENSMUST00000105049.1
keratin associated protein 17-1
chr14_+_26894557 0.02 ENSMUST00000090337.4
ENSMUST00000165929.2
ankyrin repeat and SOCS box-containing 14
chr18_-_42899294 0.02 ENSMUST00000117687.1
protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), beta isoform
chr19_-_56548122 0.01 ENSMUST00000026063.5
ENSMUST00000182276.1
DNA cross-link repair 1A, PSO2 homolog (S. cerevisiae)
chr13_-_107890059 0.01 ENSMUST00000105097.2
zinc finger SWIM-type containing 6
chr19_+_55894508 0.01 ENSMUST00000142291.1
transcription factor 7 like 2, T cell specific, HMG box
chr13_+_104287855 0.01 ENSMUST00000065766.6
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 6
chr2_+_130576170 0.01 ENSMUST00000028764.5
oxytocin
chr6_-_125165576 0.01 ENSMUST00000183272.1
ENSMUST00000182052.1
ENSMUST00000182277.1
glyceraldehyde-3-phosphate dehydrogenase
chr6_-_24168083 0.01 ENSMUST00000031713.8
solute carrier family 13 (sodium/sulfate symporters), member 1
chr11_+_94211431 0.01 ENSMUST00000041589.5
transducer of ErbB-2.1
chr18_+_20376723 0.01 ENSMUST00000076737.6
desmoglein 1 beta
chr2_-_32451396 0.01 ENSMUST00000028160.8
ENSMUST00000113310.2
solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 25
chrX_+_169685191 0.01 ENSMUST00000112104.1
ENSMUST00000112107.1
midline 1
chr12_+_105604091 0.01 ENSMUST00000041229.4
bradykinin receptor, beta 1
chr3_+_32436151 0.01 ENSMUST00000029201.7
phosphatidylinositol 3-kinase, catalytic, alpha polypeptide
chr6_-_124965248 0.01 ENSMUST00000129976.1
COP9 (constitutive photomorphogenic) homolog, subunit 7a (Arabidopsis thaliana)
chr7_-_30729505 0.01 ENSMUST00000006478.8
transmembrane protein 147
chr9_-_116175318 0.00 ENSMUST00000061101.4
ENSMUST00000035014.6
transforming growth factor, beta receptor II
chr14_+_54686171 0.00 ENSMUST00000038539.6
RIKEN cDNA 1700123O20 gene
chr15_+_21111452 0.00 ENSMUST00000075132.6
cadherin 12
chr3_+_31902507 0.00 ENSMUST00000119310.1
potassium large conductance calcium-activated channel, subfamily M, beta member 2
chr15_+_25773985 0.00 ENSMUST00000125667.1
myosin X
chr18_-_42899470 0.00 ENSMUST00000120632.1
protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), beta isoform

Network of associatons between targets according to the STRING database.

First level regulatory network of Hoxc10

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0042977 regulation of activation of JAK2 kinase activity(GO:0010534) activation of JAK2 kinase activity(GO:0042977) negative regulation of activation of JAK2 kinase activity(GO:1902569)
0.1 0.4 GO:0034760 negative regulation of iron ion transport(GO:0034757) negative regulation of iron ion transmembrane transport(GO:0034760)
0.1 0.3 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.0 0.3 GO:1901678 iron coordination entity transport(GO:1901678)
0.0 0.2 GO:0048686 regulation of sprouting of injured axon(GO:0048686) regulation of axon extension involved in regeneration(GO:0048690)
0.0 0.1 GO:0046005 positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
0.0 0.1 GO:0042231 interleukin-13 biosynthetic process(GO:0042231)
0.0 0.1 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.0 0.1 GO:0006127 glycerophosphate shuttle(GO:0006127)
0.0 0.1 GO:0033092 positive regulation of immature T cell proliferation in thymus(GO:0033092) negative regulation of adiponectin secretion(GO:0070164)
0.0 0.1 GO:0060455 negative regulation of gastric acid secretion(GO:0060455)
0.0 0.1 GO:0007208 phospholipase C-activating serotonin receptor signaling pathway(GO:0007208) positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.0 0.1 GO:0061026 cardiac muscle tissue regeneration(GO:0061026)
0.0 0.3 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.0 0.1 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.0 0.1 GO:2001280 positive regulation of prostaglandin biosynthetic process(GO:0031394) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0072534 perineuronal net(GO:0072534)
0.0 0.2 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.0 0.2 GO:1990357 terminal web(GO:1990357)
0.0 0.0 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 0.1 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.0 0.1 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0070540 stearic acid binding(GO:0070540)
0.1 0.3 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.0 0.2 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.0 0.1 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.0 0.1 GO:0030977 taurine binding(GO:0030977)
0.0 0.1 GO:0050429 calcium-dependent phospholipase C activity(GO:0050429)
0.0 0.1 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.0 0.1 GO:0052723 inositol hexakisphosphate kinase activity(GO:0000828) inositol hexakisphosphate 5-kinase activity(GO:0000832) inositol hexakisphosphate 1-kinase activity(GO:0052723) inositol hexakisphosphate 3-kinase activity(GO:0052724)
0.0 0.1 GO:0015526 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.0 0.2 GO:0046625 sphingolipid binding(GO:0046625)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells