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2D miR_HR1_12

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Results for Foxk1_Foxj1

Z-value: 0.97

Motif logo

Transcription factors associated with Foxk1_Foxj1

Gene Symbol Gene ID Gene Info
ENSMUSG00000056493.8 forkhead box K1
ENSMUSG00000034227.7 forkhead box J1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Foxk1mm10_v2_chr5_+_142401484_1424015320.519.0e-02Click!
Foxj1mm10_v2_chr11_-_116335384_1163353990.421.8e-01Click!

Activity profile of Foxk1_Foxj1 motif

Sorted Z-values of Foxk1_Foxj1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr4_-_117178726 3.36 ENSMUST00000153953.1
ENSMUST00000106436.1
kinesin family member 2C
chr1_+_130865669 2.43 ENSMUST00000038829.5
Fas apoptotic inhibitory molecule 3
chr3_+_159495408 2.38 ENSMUST00000120272.1
ENSMUST00000029825.7
ENSMUST00000106041.2
DEP domain containing 1a
chr7_+_140968028 1.82 ENSMUST00000106040.1
ENSMUST00000026564.8
interferon induced transmembrane protein 1
chr10_+_4611971 1.78 ENSMUST00000105590.1
ENSMUST00000067086.7
estrogen receptor 1 (alpha)
chrX_-_162964557 1.53 ENSMUST00000038769.2
S100 calcium binding protein G
chr5_+_30666886 1.48 ENSMUST00000144742.1
centromere protein A
chr8_-_84773381 1.20 ENSMUST00000109764.1
nuclear factor I/X
chr19_+_37376359 1.19 ENSMUST00000012587.3
kinesin family member 11
chr16_+_17146937 1.18 ENSMUST00000115706.1
ENSMUST00000069064.4
YdjC homolog (bacterial)
chr1_+_136467958 1.18 ENSMUST00000047817.6
kinesin family member 14
chr7_+_19518731 1.13 ENSMUST00000078908.4
NTPase, KAP family P-loop domain containing 1
chr14_-_57826128 1.03 ENSMUST00000022536.2
spindle and kinetochore associated complex subunit 3
chr12_-_84400851 1.02 ENSMUST00000117286.1
ectonucleoside triphosphate diphosphohydrolase 5
chrX_+_107089234 0.99 ENSMUST00000118666.1
ENSMUST00000053375.3
purinergic receptor P2Y, G-protein coupled 10
chr5_-_107687990 0.99 ENSMUST00000180428.1
predicted gene, 26692
chr7_+_141476374 0.99 ENSMUST00000117634.1
tetraspanin 4
chr3_-_100969644 0.98 ENSMUST00000076941.5
transcription termination factor, RNA polymerase II
chr4_-_43499608 0.96 ENSMUST00000136005.1
ENSMUST00000054538.6
Rho guanine nucleotide exchange factor (GEF) 39
chrY_+_90785442 0.95 ENSMUST00000177591.1
ENSMUST00000177671.1
ENSMUST00000179077.1
erythroid differentiation regulator 1
chr3_+_53488677 0.94 ENSMUST00000029307.3
stomatin (Epb7.2)-like 3
chr12_-_84400929 0.93 ENSMUST00000122194.1
ectonucleoside triphosphate diphosphohydrolase 5
chr8_-_53638945 0.88 ENSMUST00000047768.4
nei like 3 (E. coli)
chr2_+_119047116 0.86 ENSMUST00000152380.1
ENSMUST00000099542.2
cancer susceptibility candidate 5
chr5_+_150522599 0.84 ENSMUST00000044620.7
breast cancer 2
chr4_-_44710408 0.84 ENSMUST00000134968.2
ENSMUST00000173821.1
ENSMUST00000174319.1
ENSMUST00000173733.1
ENSMUST00000172866.1
ENSMUST00000165417.2
ENSMUST00000107825.2
ENSMUST00000102932.3
ENSMUST00000107827.2
ENSMUST00000107826.2
paired box gene 5
chr5_+_110330697 0.84 ENSMUST00000112481.1
polymerase (DNA directed), epsilon
chr10_+_88091070 0.83 ENSMUST00000048621.7
pro-melanin-concentrating hormone
chr5_-_135251209 0.81 ENSMUST00000062572.2
frizzled homolog 9 (Drosophila)
chrX_+_107088452 0.81 ENSMUST00000150494.1
purinergic receptor P2Y, G-protein coupled 10
chr19_+_53329413 0.76 ENSMUST00000025998.7
Max interacting protein 1
chr7_+_82175156 0.76 ENSMUST00000180243.1
SH3-domain GRB2-like 3
chr2_+_119047129 0.75 ENSMUST00000153300.1
ENSMUST00000028799.5
cancer susceptibility candidate 5
chr11_-_34833631 0.72 ENSMUST00000093191.2
spindle apparatus coiled-coil protein 1
chr1_-_179546261 0.71 ENSMUST00000027769.5
transcription factor B2, mitochondrial
chr10_-_41303171 0.69 ENSMUST00000043814.3
FIG4 homolog (S. cerevisiae)
chr8_-_70523085 0.68 ENSMUST00000137610.1
ENSMUST00000121623.1
ENSMUST00000093456.5
ENSMUST00000118850.1
KxDL motif containing 1
chr8_+_75109528 0.66 ENSMUST00000164309.1
minichromosome maintenance deficient 5, cell division cycle 46 (S. cerevisiae)
chr3_-_27896360 0.65 ENSMUST00000058077.3
transmembrane protein 212
chr8_-_41215146 0.64 ENSMUST00000034003.4
fibrinogen-like protein 1
chr2_-_176917518 0.63 ENSMUST00000108931.2
predicted gene 14296
chr4_-_82885148 0.62 ENSMUST00000048430.3
cerberus 1 homolog (Xenopus laevis)
chr7_+_78895903 0.62 ENSMUST00000107425.1
ENSMUST00000107421.1
ENSMUST00000107423.1
apoptosis enhancing nuclease
chr6_+_8520008 0.61 ENSMUST00000162567.1
ENSMUST00000161217.1
glucocorticoid induced transcript 1
chr4_+_11191354 0.59 ENSMUST00000170901.1
cyclin E2
chr14_+_3825596 0.59 ENSMUST00000178256.1
predicted gene 3002
chr14_+_3667518 0.58 ENSMUST00000112801.3
predicted gene 3020
chr14_+_5164535 0.57 ENSMUST00000179659.1
predicted gene 3317
chr13_+_119606650 0.57 ENSMUST00000178948.1
predicted gene, 21967
chr13_+_49682191 0.55 ENSMUST00000172254.1
isoleucine-tRNA synthetase
chr10_+_60106452 0.55 ENSMUST00000165024.2
sparc/osteonectin, cwcv and kazal-like domains proteoglycan 2
chr17_+_46496753 0.54 ENSMUST00000046497.6
2'-deoxynucleoside 5'-phosphate N-hydrolase 1
chr14_+_5517172 0.54 ENSMUST00000178220.1
predicted gene, 3488
chr14_-_6266620 0.53 ENSMUST00000096172.5
predicted gene 3411
chr1_+_164312879 0.52 ENSMUST00000086028.5
NME/NM23 family member 7
chr9_-_98601642 0.52 ENSMUST00000035034.8
mitochondrial ribosomal protein S22
chr11_+_46810792 0.52 ENSMUST00000068877.6
T cell immunoglobulin and mucin domain containing 4
chr1_+_164062070 0.51 ENSMUST00000097491.3
ENSMUST00000027871.7
selectin, lymphocyte
chr6_-_115037824 0.50 ENSMUST00000174848.1
ENSMUST00000032461.5
TAM41, mitochondrial translocator assembly and maintenance protein, homolog (S. cerevisiae)
chr3_+_67374116 0.48 ENSMUST00000061322.8
myeloid leukemia factor 1
chrX_+_56786527 0.48 ENSMUST00000144600.1
four and a half LIM domains 1
chr3_+_67374091 0.47 ENSMUST00000077916.5
myeloid leukemia factor 1
chr14_+_4871156 0.46 ENSMUST00000166410.2
predicted gene 3264
chr5_-_21785115 0.45 ENSMUST00000115193.1
ENSMUST00000115192.1
ENSMUST00000115195.1
ENSMUST00000030771.5
DnaJ (Hsp40) homolog, subfamily C, member 2
chr7_-_97417730 0.44 ENSMUST00000043077.7
thyroid hormone responsive
chr10_+_127677064 0.44 ENSMUST00000118612.1
ENSMUST00000048099.4
transmembrane protein 194
chr5_-_138172383 0.44 ENSMUST00000000505.9
minichromosome maintenance deficient 7 (S. cerevisiae)
chr2_+_176236860 0.42 ENSMUST00000166464.1
RIKEN cDNA 2210418O10 gene
chr3_+_94398517 0.42 ENSMUST00000050975.3
leucine rich repeat and Ig domain containing 4
chr14_+_4430992 0.41 ENSMUST00000164603.1
ENSMUST00000166848.1
predicted gene 3173
chr6_-_40999479 0.41 ENSMUST00000166306.1
predicted gene 2663
chr15_-_55548164 0.40 ENSMUST00000165356.1
mitochondrial ribosomal protein L13
chr6_-_129740484 0.40 ENSMUST00000050385.5
killer cell lectin-like receptor family I member 2
chr8_+_58912257 0.40 ENSMUST00000160055.1
cDNA sequence BC030500
chr1_+_34439851 0.39 ENSMUST00000027303.7
IMP4, U3 small nucleolar ribonucleoprotein, homolog (yeast)
chr14_-_8318023 0.39 ENSMUST00000120411.1
family with sequence similarity 107, member A
chr11_+_46235460 0.39 ENSMUST00000060185.2
fibronectin type III domain containing 9
chr14_+_4514758 0.39 ENSMUST00000112776.2
predicted gene 3173
chr17_-_26095487 0.39 ENSMUST00000025007.5
NME/NM23 nucleoside diphosphate kinase 4
chr6_-_112696604 0.38 ENSMUST00000113182.1
ENSMUST00000113180.1
ENSMUST00000068487.5
ENSMUST00000077088.4
RAD18 homolog (S. cerevisiae)
chr4_+_11558914 0.38 ENSMUST00000178703.1
ENSMUST00000095145.5
ENSMUST00000108306.2
ENSMUST00000070755.6
RAD54 homolog B (S. cerevisiae)
chr1_-_144177259 0.38 ENSMUST00000111941.1
ENSMUST00000052375.1
regulator of G-protein signaling 13
chr17_+_56613392 0.37 ENSMUST00000080492.5
ribosomal protein L36
chr14_-_6741430 0.36 ENSMUST00000100904.4
predicted gene 3636
chrX_+_102119447 0.36 ENSMUST00000113627.3
protein (peptidyl-prolyl cis/trans isomerase) NIMA-interacting, 4 (parvulin)
chr7_-_27985796 0.36 ENSMUST00000099111.3
zinc finger protein 850
chr13_+_43370710 0.36 ENSMUST00000066804.4
sirtuin 5
chr3_-_16006332 0.36 ENSMUST00000108347.2
predicted gene 5150
chr1_+_66386968 0.35 ENSMUST00000145419.1
microtubule-associated protein 2
chr9_+_5345450 0.35 ENSMUST00000151332.1
caspase 12
chr2_+_12924041 0.34 ENSMUST00000134794.1
ENSMUST00000028063.4
ENSMUST00000154269.1
ENSMUST00000114796.3
phosphotriesterase related
chr11_-_75348261 0.34 ENSMUST00000000767.5
ENSMUST00000092907.5
replication protein A1
chrX_+_9885622 0.34 ENSMUST00000067529.2
ENSMUST00000086165.3
synaptotagmin-like 5
chr3_+_129532386 0.34 ENSMUST00000071402.2
ELOVL family member 6, elongation of long chain fatty acids (yeast)
chr17_+_55749978 0.34 ENSMUST00000025004.6
EGF-like module containing, mucin-like, hormone receptor-like sequence 4
chr3_-_101287879 0.34 ENSMUST00000152321.1
CD2 antigen
chr10_-_62792243 0.34 ENSMUST00000020268.5
cell division cycle and apoptosis regulator 1
chr3_-_101287897 0.34 ENSMUST00000029456.4
CD2 antigen
chr15_-_50882806 0.33 ENSMUST00000184885.1
trichorhinophalangeal syndrome I (human)
chr12_-_71136611 0.33 ENSMUST00000021486.8
ENSMUST00000166120.1
translocase of inner mitochondrial membrane 9
chr1_+_171225054 0.32 ENSMUST00000111321.1
ENSMUST00000005824.5
ENSMUST00000111320.1
ENSMUST00000111319.1
apolipoprotein A-II
chr3_-_30793549 0.32 ENSMUST00000180833.1
RIKEN cDNA 4933429H19 gene
chr2_-_104028287 0.31 ENSMUST00000056170.3
RIKEN cDNA 4931422A03 gene
chr5_-_151651216 0.31 ENSMUST00000038131.9
replication factor C (activator 1) 3
chr18_+_4993795 0.31 ENSMUST00000153016.1
supervillin
chr1_+_34005872 0.31 ENSMUST00000182296.1
dystonin
chr1_-_138175238 0.31 ENSMUST00000182536.1
protein tyrosine phosphatase, receptor type, C
chr6_-_136941887 0.31 ENSMUST00000111891.1
Rho, GDP dissociation inhibitor (GDI) beta
chr19_-_9135603 0.31 ENSMUST00000049948.5
asparaginase like 1
chr2_-_64975762 0.31 ENSMUST00000156765.1
growth factor receptor bound protein 14
chr13_-_74376566 0.31 ENSMUST00000091481.2
zinc finger protein 72
chr6_+_79818031 0.31 ENSMUST00000179797.1
predicted gene, 20594
chr8_-_27202542 0.31 ENSMUST00000038174.6
glutamic-oxaloacetic transaminase 1-like 1
chr6_+_38534823 0.30 ENSMUST00000019833.4
RIKEN cDNA 1110001J03 gene
chr2_-_73452666 0.30 ENSMUST00000151939.1
WAS/WASL interacting protein family, member 1
chr1_-_138175283 0.30 ENSMUST00000182755.1
ENSMUST00000183262.1
ENSMUST00000027645.7
ENSMUST00000112036.2
ENSMUST00000182283.1
protein tyrosine phosphatase, receptor type, C
chr6_+_42264983 0.30 ENSMUST00000031895.6
caspase 2
chr17_-_12868126 0.30 ENSMUST00000089015.3
MAS1 oncogene
chr14_+_75131499 0.29 ENSMUST00000125833.1
ENSMUST00000124499.1
lymphocyte cytosolic protein 1
chr17_+_35194405 0.28 ENSMUST00000025262.5
lymphotoxin B
chr4_-_154097105 0.28 ENSMUST00000105643.1
ENSMUST00000133533.1
ENSMUST00000097762.4
transformation related protein 73
chr3_+_68584154 0.28 ENSMUST00000182997.1
schwannomin interacting protein 1
chr9_-_107872403 0.28 ENSMUST00000183035.1
RNA binding motif protein 6
chr19_+_11443573 0.28 ENSMUST00000035258.8
membrane-spanning 4-domains, subfamily A, member 4B
chr4_+_33209259 0.28 ENSMUST00000108159.1
serine/arginine-rich splicing factor 12
chr3_+_145987835 0.27 ENSMUST00000039517.6
synapse defective 1, Rho GTPase, homolog 2 (C. elegans)
chr16_-_76022266 0.27 ENSMUST00000114240.1
SAM domain, SH3 domain and nuclear localization signals, 1
chr13_+_4059565 0.27 ENSMUST00000041768.6
aldo-keto reductase family 1, member C14
chr16_-_15637277 0.27 ENSMUST00000023353.3
minichromosome maintenance deficient 4 homolog (S. cerevisiae)
chr17_+_35194502 0.27 ENSMUST00000173600.1
lymphotoxin B
chr10_+_39420009 0.27 ENSMUST00000157009.1
Fyn proto-oncogene
chr6_-_120357342 0.27 ENSMUST00000163827.1
coiled-coil domain containing 77
chr2_+_38511643 0.26 ENSMUST00000054234.3
ENSMUST00000112902.1
ENSMUST00000112895.1
NIMA (never in mitosis gene a)-related expressed kinase 6
chr18_+_67800101 0.26 ENSMUST00000025425.5
centrosomal protein 192
chr4_+_95579463 0.26 ENSMUST00000150830.1
ENSMUST00000134012.2
FGGY carbohydrate kinase domain containing
chr10_-_127522428 0.26 ENSMUST00000026470.4
serine hydroxymethyltransferase 2 (mitochondrial)
chr16_+_65815508 0.26 ENSMUST00000168064.1
vestigial like 3 (Drosophila)
chr1_-_63769267 0.26 ENSMUST00000027102.1
RIKEN cDNA 4933402D24 gene
chr14_+_75131101 0.26 ENSMUST00000143539.1
ENSMUST00000134114.1
lymphocyte cytosolic protein 1
chr3_+_138217814 0.26 ENSMUST00000090171.5
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr1_-_138175126 0.26 ENSMUST00000183301.1
protein tyrosine phosphatase, receptor type, C
chr1_-_119913162 0.25 ENSMUST00000037906.5
transmembrane protein 177
chr2_+_65620829 0.25 ENSMUST00000028377.7
sodium channel, voltage-gated, type II, alpha 1
chr15_-_77022632 0.25 ENSMUST00000019037.8
ENSMUST00000169226.1
myoglobin
chr4_-_45108038 0.25 ENSMUST00000107809.2
ENSMUST00000107808.2
ENSMUST00000107807.1
ENSMUST00000107810.2
translocase of outer mitochondrial membrane 5 homolog (yeast)
chr6_-_129533267 0.24 ENSMUST00000181594.1
RIKEN cDNA 1700101I11 gene
chr19_-_28011138 0.24 ENSMUST00000174850.1
regulatory factor X, 3 (influences HLA class II expression)
chr2_-_65567505 0.24 ENSMUST00000100069.2
sodium channel, voltage-gated, type III, alpha
chr3_+_58526303 0.24 ENSMUST00000138848.1
eukaryotic translation initiation factor 2A
chr19_-_28010995 0.24 ENSMUST00000172907.1
ENSMUST00000046898.9
regulatory factor X, 3 (influences HLA class II expression)
chr8_+_3567958 0.24 ENSMUST00000136592.1
RIKEN cDNA C330021F23 gene
chr3_-_30599863 0.24 ENSMUST00000047630.6
actin related protein T3
chr12_-_103443653 0.24 ENSMUST00000055071.8
interferon, alpha-inducible protein 27 like 2A
chr17_+_34092340 0.23 ENSMUST00000025192.7
histocompatibility 2, O region alpha locus
chr2_-_151009364 0.23 ENSMUST00000109896.1
ninein-like
chr5_+_136038496 0.23 ENSMUST00000062606.6
uroplakin 3B
chr8_-_39642669 0.23 ENSMUST00000026021.6
ENSMUST00000170091.1
macrophage scavenger receptor 1
chr1_-_75046639 0.23 ENSMUST00000152855.1
nonhomologous end-joining factor 1
chr5_+_62813823 0.23 ENSMUST00000170704.1
predicted gene, 17384
chr13_+_60602182 0.23 ENSMUST00000044083.7
death associated protein kinase 1
chr4_-_87806276 0.23 ENSMUST00000148059.1
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr1_-_85270543 0.23 ENSMUST00000093506.5
ENSMUST00000064341.8
RIKEN cDNA C130026I21 gene
chr9_+_65361049 0.23 ENSMUST00000147185.1
predicted gene 514
chr16_-_19706365 0.23 ENSMUST00000081880.5
lysosomal-associated membrane protein 3
chr15_-_97020322 0.22 ENSMUST00000166223.1
solute carrier family 38, member 4
chr2_-_17460610 0.22 ENSMUST00000145492.1
nebulette
chr8_+_66386292 0.22 ENSMUST00000039540.5
ENSMUST00000110253.2
membrane-associated ring finger (C3HC4) 1
chr16_-_36666067 0.22 ENSMUST00000089620.4
CD86 antigen
chr1_-_58504946 0.22 ENSMUST00000027198.5
origin recognition complex, subunit 2
chr19_+_44992127 0.22 ENSMUST00000179305.1
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
chr9_+_123806468 0.22 ENSMUST00000049810.7
chemokine (C-X-C motif) receptor 6
chr18_+_40256960 0.21 ENSMUST00000096572.1
RIKEN cDNA 2900055J20 gene
chr3_-_10208569 0.21 ENSMUST00000029041.4
fatty acid binding protein 4, adipocyte
chr8_+_20136455 0.21 ENSMUST00000179299.1
ENSMUST00000096485.4
predicted gene, 21811
chr10_+_18469958 0.21 ENSMUST00000162891.1
ENSMUST00000100054.3
NHS-like 1
chr11_+_98026695 0.21 ENSMUST00000092425.4
ribosomal protein L19
chr4_-_129662442 0.21 ENSMUST00000003828.4
karyopherin (importin) alpha 6
chr10_-_127030813 0.21 ENSMUST00000040560.4
Ts translation elongation factor, mitochondrial
chr15_+_76343504 0.21 ENSMUST00000023210.6
cytochrome c-1
chr4_+_135911808 0.21 ENSMUST00000068830.3
cannabinoid receptor 2 (macrophage)
chr1_+_45311538 0.21 ENSMUST00000087883.6
collagen, type III, alpha 1
chrX_+_71364745 0.21 ENSMUST00000114601.1
ENSMUST00000146213.1
ENSMUST00000015358.1
myotubularin related protein 1
chr8_+_93810832 0.21 ENSMUST00000034198.8
ENSMUST00000125716.1
guanine nucleotide binding protein, alpha O
chr2_-_80128834 0.20 ENSMUST00000102654.4
ENSMUST00000102655.3
phosphodiesterase 1A, calmodulin-dependent
chr2_+_68117713 0.20 ENSMUST00000112346.2
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1
chr10_+_127705170 0.20 ENSMUST00000079590.5
myosin IA
chr6_-_86765866 0.20 ENSMUST00000113675.1
annexin A4
chr8_+_70673198 0.20 ENSMUST00000034311.8
LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr10_-_127030789 0.20 ENSMUST00000120547.1
ENSMUST00000152054.1
Ts translation elongation factor, mitochondrial
chr8_-_107588392 0.20 ENSMUST00000044106.4
proteasome (prosome, macropain) 26S subunit, non-ATPase, 7
chr10_-_30600662 0.20 ENSMUST00000019927.6
tRNA methyltransferase 11
chr18_-_43373248 0.20 ENSMUST00000118043.1
dihydropyrimidinase-like 3
chr1_+_10056922 0.20 ENSMUST00000149214.1
centrosome and spindle pole associated protein 1
chr15_+_78406777 0.20 ENSMUST00000169133.1
mercaptopyruvate sulfurtransferase
chr13_-_14613017 0.20 ENSMUST00000015816.3
mitochondrial ribosomal protein L32
chr11_-_3266377 0.20 ENSMUST00000020741.5
developmentally regulated GTP binding protein 1
chr18_-_74961252 0.19 ENSMUST00000066532.4
lipase, endothelial
chrX_+_56872543 0.19 ENSMUST00000153784.1
G protein-coupled receptor 112
chr13_+_4574075 0.19 ENSMUST00000021628.3
aldo-keto reductase family 1, member C21
chr4_-_62470868 0.19 ENSMUST00000135811.1
ENSMUST00000120095.1
ENSMUST00000030087.7
ENSMUST00000107452.1
ENSMUST00000155522.1
WD repeat domain 31

Network of associatons between targets according to the STRING database.

First level regulatory network of Foxk1_Foxj1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 3.4 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.4 1.2 GO:0033624 negative regulation of integrin activation(GO:0033624)
0.3 1.8 GO:0060011 Sertoli cell proliferation(GO:0060011) prostate epithelial cord elongation(GO:0060523)
0.3 0.8 GO:0090172 microtubule cytoskeleton organization involved in homologous chromosome segregation(GO:0090172)
0.3 0.8 GO:0045004 DNA replication proofreading(GO:0045004)
0.3 0.8 GO:0046005 positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
0.3 0.8 GO:1990523 bone regeneration(GO:1990523)
0.2 0.6 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
0.2 0.9 GO:0002378 immunoglobulin biosynthetic process(GO:0002378) regulation of hematopoietic stem cell migration(GO:2000471) positive regulation of hematopoietic stem cell migration(GO:2000473)
0.2 0.6 GO:1900108 sequestering of BMP in extracellular matrix(GO:0035582) negative regulation of nodal signaling pathway(GO:1900108)
0.1 2.2 GO:0071459 protein localization to chromosome, centromeric region(GO:0071459)
0.1 1.2 GO:0046602 regulation of mitotic centrosome separation(GO:0046602)
0.1 0.5 GO:0060830 ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
0.1 0.2 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.1 0.3 GO:1903538 meiotic cell cycle process involved in oocyte maturation(GO:1903537) regulation of meiotic cell cycle process involved in oocyte maturation(GO:1903538)
0.1 0.4 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.1 0.3 GO:0006532 aspartate biosynthetic process(GO:0006532)
0.1 0.5 GO:0002069 columnar/cuboidal epithelial cell maturation(GO:0002069) positive regulation of type B pancreatic cell development(GO:2000078)
0.1 0.7 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.1 0.9 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
0.1 0.2 GO:0007208 phospholipase C-activating serotonin receptor signaling pathway(GO:0007208) positive regulation of phosphatidylinositol biosynthetic process(GO:0010513)
0.1 0.3 GO:0046340 diacylglycerol catabolic process(GO:0046340)
0.1 0.7 GO:0031642 negative regulation of myelination(GO:0031642)
0.1 0.2 GO:0002644 negative regulation of tolerance induction(GO:0002644)
0.1 1.9 GO:0051084 'de novo' posttranslational protein folding(GO:0051084)
0.1 0.7 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.1 1.6 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.1 0.3 GO:1902951 negative regulation of dendritic spine maintenance(GO:1902951)
0.1 0.3 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.1 0.3 GO:0006069 ethanol oxidation(GO:0006069)
0.1 1.1 GO:0021707 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.1 0.5 GO:0032049 cardiolipin biosynthetic process(GO:0032049)
0.1 0.2 GO:0015671 oxygen transport(GO:0015671)
0.1 0.6 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.1 0.5 GO:0009162 deoxyribonucleoside monophosphate metabolic process(GO:0009162)
0.1 0.2 GO:0002587 negative regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002587)
0.1 0.4 GO:2000483 negative regulation of interleukin-8 secretion(GO:2000483)
0.1 0.8 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.1 0.2 GO:1904760 myofibroblast differentiation(GO:0036446) regulation of myofibroblast differentiation(GO:1904760)
0.1 0.2 GO:2000686 regulation of rubidium ion transmembrane transporter activity(GO:2000686)
0.1 0.3 GO:1902167 cerebrospinal fluid secretion(GO:0033326) positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902167)
0.1 1.0 GO:0006353 DNA-templated transcription, termination(GO:0006353)
0.1 0.7 GO:1902715 positive regulation of interferon-gamma secretion(GO:1902715)
0.1 0.3 GO:0006545 glycine biosynthetic process(GO:0006545) L-serine biosynthetic process(GO:0006564)
0.0 0.1 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.0 0.2 GO:0010986 regulation of high-density lipoprotein particle clearance(GO:0010982) positive regulation of lipoprotein particle clearance(GO:0010986)
0.0 0.2 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
0.0 0.0 GO:0002408 myeloid dendritic cell chemotaxis(GO:0002408)
0.0 0.1 GO:0002223 stimulatory C-type lectin receptor signaling pathway(GO:0002223)
0.0 1.6 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.0 1.0 GO:0021670 lateral ventricle development(GO:0021670)
0.0 0.3 GO:0009068 asparagine metabolic process(GO:0006528) aspartate family amino acid catabolic process(GO:0009068)
0.0 0.1 GO:0000715 nucleotide-excision repair, DNA damage recognition(GO:0000715)
0.0 0.5 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.2 GO:0046684 response to pyrethroid(GO:0046684)
0.0 1.3 GO:0006270 DNA replication initiation(GO:0006270)
0.0 0.2 GO:1990928 response to amino acid starvation(GO:1990928)
0.0 0.1 GO:1902071 regulation of hypoxia-inducible factor-1alpha signaling pathway(GO:1902071)
0.0 0.4 GO:0006228 UTP biosynthetic process(GO:0006228)
0.0 0.3 GO:1901164 negative regulation of trophoblast cell migration(GO:1901164)
0.0 0.1 GO:0015755 fructose transport(GO:0015755)
0.0 0.3 GO:0010886 positive regulation of cholesterol storage(GO:0010886)
0.0 0.1 GO:0015766 disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.0 0.3 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.0 0.2 GO:0042776 response to glucagon(GO:0033762) mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 0.2 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.0 0.4 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 0.3 GO:0044791 modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
0.0 0.1 GO:1903027 regulation of opsonization(GO:1903027) positive regulation of opsonization(GO:1903028)
0.0 0.2 GO:0019346 homoserine metabolic process(GO:0009092) transsulfuration(GO:0019346)
0.0 0.1 GO:1902045 regulation of Fas signaling pathway(GO:1902044) negative regulation of Fas signaling pathway(GO:1902045)
0.0 0.2 GO:0071475 cellular hyperosmotic salinity response(GO:0071475)
0.0 0.2 GO:0042904 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0 0.3 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.1 GO:0090232 positive regulation of spindle checkpoint(GO:0090232)
0.0 0.6 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.0 0.6 GO:0035634 response to stilbenoid(GO:0035634)
0.0 0.4 GO:0019321 pentose metabolic process(GO:0019321)
0.0 0.4 GO:0032740 positive regulation of interleukin-17 production(GO:0032740)
0.0 0.5 GO:0016540 protein autoprocessing(GO:0016540)
0.0 0.1 GO:0002282 microglial cell activation involved in immune response(GO:0002282)
0.0 0.2 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.0 0.1 GO:2000304 positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.0 0.1 GO:0035995 detection of muscle stretch(GO:0035995)
0.0 0.1 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.0 1.2 GO:0006284 base-excision repair(GO:0006284)
0.0 0.1 GO:2001168 regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168)
0.0 0.2 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.2 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0 0.1 GO:0060931 sinoatrial node cell development(GO:0060931)
0.0 0.3 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977)
0.0 0.4 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 0.1 GO:0003032 detection of oxygen(GO:0003032)
0.0 0.2 GO:2000002 negative regulation of DNA damage checkpoint(GO:2000002)
0.0 0.4 GO:0007202 activation of phospholipase C activity(GO:0007202)
0.0 0.0 GO:0002760 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) regulation of antimicrobial peptide production(GO:0002784) regulation of antibacterial peptide production(GO:0002786) positive regulation of antibacterial peptide production(GO:0002803)
0.0 0.1 GO:0090274 estrous cycle(GO:0044849) positive regulation of somatostatin secretion(GO:0090274)
0.0 0.2 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.4 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.5 GO:0090023 positive regulation of neutrophil chemotaxis(GO:0090023)
0.0 0.4 GO:0051984 positive regulation of chromosome segregation(GO:0051984)
0.0 0.2 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.0 0.5 GO:0050872 white fat cell differentiation(GO:0050872)
0.0 0.2 GO:0042126 nitrate metabolic process(GO:0042126)
0.0 0.2 GO:0097475 motor neuron migration(GO:0097475)
0.0 0.2 GO:0045759 negative regulation of synaptic transmission, GABAergic(GO:0032229) negative regulation of action potential(GO:0045759)
0.0 0.1 GO:0097401 synaptic vesicle lumen acidification(GO:0097401)
0.0 0.1 GO:0000414 regulation of histone H3-K36 methylation(GO:0000414)
0.0 0.1 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 0.1 GO:0090472 dibasic protein processing(GO:0090472)
0.0 0.1 GO:0007521 muscle cell fate determination(GO:0007521)
0.0 0.2 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
0.0 0.1 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.0 GO:0046985 positive regulation of hemoglobin biosynthetic process(GO:0046985)
0.0 0.2 GO:0071447 cellular response to hydroperoxide(GO:0071447)
0.0 0.4 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.0 0.1 GO:1990401 embryonic lung development(GO:1990401)
0.0 0.4 GO:0010866 regulation of triglyceride biosynthetic process(GO:0010866)
0.0 0.1 GO:0002159 desmosome assembly(GO:0002159) response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681)
0.0 0.1 GO:0010808 positive regulation of synaptic vesicle priming(GO:0010808)
0.0 0.0 GO:0002430 complement receptor mediated signaling pathway(GO:0002430)
0.0 0.1 GO:0015889 cobalamin transport(GO:0015889)
0.0 0.1 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.0 0.1 GO:0051581 negative regulation of neurotransmitter uptake(GO:0051581) negative regulation of serotonin uptake(GO:0051612)
0.0 0.1 GO:1990253 cellular response to leucine starvation(GO:1990253)
0.0 0.2 GO:0016188 synaptic vesicle maturation(GO:0016188)
0.0 0.4 GO:0008340 determination of adult lifespan(GO:0008340)
0.0 0.1 GO:0006071 glycerol metabolic process(GO:0006071)
0.0 0.0 GO:0030450 regulation of complement activation, classical pathway(GO:0030450)
0.0 0.2 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.1 GO:0060051 negative regulation of protein glycosylation(GO:0060051)
0.0 0.0 GO:0046984 regulation of hemoglobin biosynthetic process(GO:0046984)
0.0 0.2 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.9 GO:0035019 somatic stem cell population maintenance(GO:0035019)
0.0 0.3 GO:0008210 estrogen metabolic process(GO:0008210)
0.0 0.3 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.0 0.5 GO:0030071 regulation of mitotic metaphase/anaphase transition(GO:0030071)
0.0 0.7 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.0 0.4 GO:0010667 negative regulation of cardiac muscle cell apoptotic process(GO:0010667)
0.0 0.4 GO:2000279 negative regulation of DNA biosynthetic process(GO:2000279)
0.0 0.0 GO:0070318 positive regulation of G0 to G1 transition(GO:0070318)
0.0 0.1 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.0 0.0 GO:0097309 cap1 mRNA methylation(GO:0097309)
0.0 0.3 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 0.2 GO:0035455 response to interferon-alpha(GO:0035455)
0.0 1.2 GO:0031110 regulation of microtubule polymerization or depolymerization(GO:0031110)
0.0 0.0 GO:2000210 positive regulation of anoikis(GO:2000210)
0.0 0.3 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.0 GO:0009794 regulation of mitotic cell cycle, embryonic(GO:0009794) mitotic cell cycle, embryonic(GO:0045448)
0.0 0.1 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.0 0.1 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.1 GO:1901844 regulation of cell communication by electrical coupling involved in cardiac conduction(GO:1901844)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.7 GO:0000939 condensed chromosome inner kinetochore(GO:0000939)
0.3 1.8 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.2 0.6 GO:0097135 cyclin E2-CDK2 complex(GO:0097135)
0.2 0.8 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.1 1.8 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.1 0.4 GO:0034457 Mpp10 complex(GO:0034457)
0.1 1.4 GO:0042555 MCM complex(GO:0042555)
0.1 3.3 GO:0035371 microtubule plus-end(GO:0035371)
0.1 0.2 GO:0097232 lamellar body membrane(GO:0097232) alveolar lamellar body membrane(GO:0097233)
0.1 0.3 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.1 0.3 GO:0014802 terminal cisterna(GO:0014802)
0.1 0.3 GO:0070552 BRISC complex(GO:0070552)
0.1 0.3 GO:0005663 DNA replication factor C complex(GO:0005663)
0.1 0.3 GO:0031673 H zone(GO:0031673)
0.1 0.2 GO:0071797 LUBAC complex(GO:0071797)
0.0 0.1 GO:0042585 germinal vesicle(GO:0042585)
0.0 0.4 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.0 0.2 GO:0032807 DNA ligase IV complex(GO:0032807)
0.0 1.2 GO:0000800 lateral element(GO:0000800)
0.0 0.2 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.0 1.2 GO:0051233 spindle midzone(GO:0051233)
0.0 0.6 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.4 GO:0000243 commitment complex(GO:0000243)
0.0 0.6 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.1 GO:0071942 XPC complex(GO:0071942)
0.0 0.2 GO:1990111 spermatoproteasome complex(GO:1990111)
0.0 0.7 GO:0031527 filopodium membrane(GO:0031527)
0.0 0.2 GO:0030062 mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.0 0.2 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.4 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.3 GO:0005688 U6 snRNP(GO:0005688)
0.0 0.2 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 1.1 GO:0097546 ciliary base(GO:0097546)
0.0 0.8 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.3 GO:0001673 male germ cell nucleus(GO:0001673)
0.0 0.3 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.2 GO:0031415 NatA complex(GO:0031415)
0.0 1.1 GO:0005876 spindle microtubule(GO:0005876)
0.0 0.3 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.0 0.2 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750)
0.0 2.1 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.3 GO:0016589 NURF complex(GO:0016589)
0.0 0.1 GO:1990923 PET complex(GO:1990923)
0.0 0.1 GO:0033503 HULC complex(GO:0033503)
0.0 0.5 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.2 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.2 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.2 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.1 GO:0098831 presynaptic active zone cytoplasmic component(GO:0098831)
0.0 0.7 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.6 GO:0042645 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.0 0.3 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.3 GO:0005838 proteasome regulatory particle(GO:0005838)
0.0 0.1 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.0 0.2 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.7 GO:0031970 mitochondrial intermembrane space(GO:0005758) organelle envelope lumen(GO:0031970)
0.0 0.1 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.0 0.8 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.1 GO:0071664 catenin-TCF7L2 complex(GO:0071664)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.8 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798)
0.4 1.9 GO:0004382 guanosine-diphosphatase activity(GO:0004382)
0.2 0.7 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.2 1.5 GO:0005499 vitamin D binding(GO:0005499)
0.2 0.8 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.2 0.6 GO:0016015 morphogen activity(GO:0016015)
0.2 3.3 GO:0051010 microtubule plus-end binding(GO:0051010)
0.2 0.2 GO:1902121 lithocholic acid binding(GO:1902121)
0.2 0.6 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
0.2 0.7 GO:0043515 kinetochore binding(GO:0043515)
0.2 0.9 GO:0000405 bubble DNA binding(GO:0000405)
0.2 0.5 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.1 0.4 GO:0019150 D-ribulokinase activity(GO:0019150)
0.1 0.7 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.1 0.4 GO:0030519 snoRNP binding(GO:0030519)
0.1 0.8 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.1 1.3 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1 0.3 GO:0004069 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069)
0.1 0.4 GO:0003681 bent DNA binding(GO:0003681)
0.1 0.3 GO:0004793 threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.1 0.3 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.1 0.3 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
0.1 0.4 GO:0000403 Y-form DNA binding(GO:0000403)
0.1 0.4 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.1 2.2 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.1 0.4 GO:1990932 5.8S rRNA binding(GO:1990932)
0.1 0.9 GO:0003688 DNA replication origin binding(GO:0003688)
0.1 0.2 GO:0030156 benzodiazepine receptor binding(GO:0030156)
0.1 0.2 GO:0005344 oxygen transporter activity(GO:0005344)
0.1 0.2 GO:0008940 nitrate reductase activity(GO:0008940)
0.1 0.2 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.1 0.2 GO:0004774 succinate-CoA ligase activity(GO:0004774)
0.1 0.4 GO:0015616 DNA translocase activity(GO:0015616)
0.1 0.4 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1 0.3 GO:0042610 CD8 receptor binding(GO:0042610)
0.1 0.2 GO:0035827 rubidium ion transmembrane transporter activity(GO:0035827)
0.1 0.2 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.1 0.2 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.0 0.3 GO:0001595 angiotensin receptor activity(GO:0001595)
0.0 0.3 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.0 0.4 GO:1901612 cardiolipin binding(GO:1901612)
0.0 0.2 GO:0004832 valine-tRNA ligase activity(GO:0004832)
0.0 0.6 GO:0097153 cysteine-type endopeptidase activity involved in apoptotic process(GO:0097153)
0.0 0.4 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.0 0.1 GO:0005275 amine transmembrane transporter activity(GO:0005275)
0.0 0.2 GO:0042731 PH domain binding(GO:0042731)
0.0 0.2 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.0 0.2 GO:0004792 thiosulfate sulfurtransferase activity(GO:0004792)
0.0 0.3 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 1.1 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.0 0.2 GO:0019958 C-X-C chemokine binding(GO:0019958)
0.0 0.1 GO:0015154 sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.0 0.8 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.2 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.3 GO:0102338 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.1 GO:0019237 centromeric DNA binding(GO:0019237)
0.0 0.9 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 1.5 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.3 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.5 GO:0051861 glycolipid binding(GO:0051861)
0.0 0.3 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.0 0.1 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.0 0.2 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.0 0.1 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.5 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.1 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.0 0.3 GO:0008242 omega peptidase activity(GO:0008242)
0.0 0.5 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds(GO:0016799)
0.0 0.2 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993) serotonin binding(GO:0051378)
0.0 0.7 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.2 GO:0003909 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0 0.4 GO:0017081 chloride channel regulator activity(GO:0017081)
0.0 1.7 GO:0003823 antigen binding(GO:0003823)
0.0 0.5 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.1 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.0 0.1 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 0.1 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316)
0.0 0.4 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.7 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.1 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.6 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.1 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.2 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.1 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.0 0.4 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.4 GO:0042287 MHC protein binding(GO:0042287)
0.0 0.1 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.0 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0 0.1 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.0 0.1 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 0.1 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.0 0.2 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.0 0.2 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.1 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.0 0.1 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.2 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 0.2 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.0 0.0 GO:0005124 scavenger receptor binding(GO:0005124)
0.0 0.0 GO:0036033 mediator complex binding(GO:0036033)
0.0 0.3 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.2 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.3 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 0.8 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 2.0 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.2 GO:0017166 vinculin binding(GO:0017166)
0.0 0.0 GO:0004974 leukotriene receptor activity(GO:0004974)
0.0 0.1 GO:0047391 alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.0 0.1 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.8 PID AURORA B PATHWAY Aurora B signaling
0.1 0.6 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 2.2 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 0.5 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.8 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 1.1 PID ATR PATHWAY ATR signaling pathway
0.0 1.5 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 0.6 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.0 0.4 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 0.6 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.4 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 1.0 PID P73PATHWAY p73 transcription factor network
0.0 1.1 PID CMYB PATHWAY C-MYB transcription factor network
0.0 0.2 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.5 REACTOME KINESINS Genes involved in Kinesins
0.1 1.5 REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.1 1.1 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.1 1.4 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.1 1.0 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1 3.1 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.1 0.8 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.1 2.5 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.7 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.3 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 1.8 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.0 0.5 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.7 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.2 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.0 0.3 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.2 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0 0.5 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.2 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.2 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.2 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.0 1.0 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.3 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.0 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.0 0.4 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.1 REACTOME GLOBAL GENOMIC NER GG NER Genes involved in Global Genomic NER (GG-NER)
0.0 0.1 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.3 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.1 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.3 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.0 0.3 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.2 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.4 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.1 REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.0 0.2 REACTOME TRNA AMINOACYLATION Genes involved in tRNA Aminoacylation
0.0 0.2 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules