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2D miR_HR1_12

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Results for Spib

Z-value: 1.73

Motif logo

Transcription factors associated with Spib

Gene Symbol Gene ID Gene Info
ENSMUSG00000008193.7 Spi-B transcription factor (Spi-1/PU.1 related)

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Spibmm10_v2_chr7_-_44532064_445320780.234.7e-01Click!

Activity profile of Spib motif

Sorted Z-values of Spib motif

Promoter Log-likelihood Transcript Gene Gene Info
chr15_+_78325990 1.97 ENSMUST00000096355.3
colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)
chr1_-_173333503 1.92 ENSMUST00000038227.4
Duffy blood group, chemokine receptor
chr6_+_38918969 1.86 ENSMUST00000003017.6
thromboxane A synthase 1, platelet
chr7_-_3720382 1.84 ENSMUST00000078451.6
paired Ig-like receptor B
chr7_-_45238794 1.72 ENSMUST00000098461.1
ENSMUST00000107797.1
CD37 antigen
chr19_-_11081088 1.71 ENSMUST00000025636.6
membrane-spanning 4-domains, subfamily A, member 8A
chr2_+_24345305 1.69 ENSMUST00000114482.1
interleukin 1 receptor antagonist
chr7_-_45239108 1.69 ENSMUST00000033063.6
CD37 antigen
chr5_-_123141067 1.66 ENSMUST00000162697.1
ENSMUST00000160321.1
ENSMUST00000159637.1
expressed sequence AI480526
chr15_-_78305603 1.63 ENSMUST00000096356.3
colony stimulating factor 2 receptor, beta 2, low-affinity (granulocyte-macrophage)
chr5_-_134229581 1.63 ENSMUST00000111275.1
ENSMUST00000016094.6
ENSMUST00000144086.1
neutrophil cytosolic factor 1
chr7_-_45239041 1.61 ENSMUST00000131290.1
CD37 antigen
chr7_-_3845050 1.59 ENSMUST00000108615.3
ENSMUST00000119469.1
paired-Ig-like receptor A2
chr15_-_99705490 1.56 ENSMUST00000163472.2
predicted gene, 17349
chr6_+_129350237 1.55 ENSMUST00000065289.4
C-type lectin domain family 12, member a
chr2_+_91096744 1.53 ENSMUST00000132741.2
spleen focus forming virus (SFFV) proviral integration oncogene
chr9_+_21526144 1.53 ENSMUST00000086361.5
ENSMUST00000179459.1
ENSMUST00000173769.2
cDNA sequence AB124611
chr7_-_3898120 1.47 ENSMUST00000070639.7
predicted gene 14548
chr1_-_170976112 1.46 ENSMUST00000027966.7
ENSMUST00000081103.5
ENSMUST00000159688.1
Fc receptor, IgG, low affinity IIb
chr5_+_81021202 1.41 ENSMUST00000117253.1
ENSMUST00000120128.1
latrophilin 3
chr11_-_115062177 1.37 ENSMUST00000062787.7
CD300e antigen
chr15_-_66812593 1.36 ENSMUST00000100572.3
src-like adaptor
chr3_-_105932664 1.35 ENSMUST00000098758.2
RIKEN cDNA I830077J02 gene
chr12_-_86988676 1.30 ENSMUST00000095521.2
zinc finger, DHHC-type containing 22
chr11_+_11685909 1.28 ENSMUST00000065433.5
IKAROS family zinc finger 1
chr17_+_48232755 1.27 ENSMUST00000113251.3
ENSMUST00000048782.6
triggering receptor expressed on myeloid cells 1
chr6_+_122952515 1.26 ENSMUST00000117173.1
ENSMUST00000088468.4
C-type lectin domain family 4, member a3
chr9_+_56089962 1.25 ENSMUST00000059206.7
proline-serine-threonine phosphatase-interacting protein 1
chr11_+_70130329 1.23 ENSMUST00000041550.5
ENSMUST00000165951.1
macrophage galactose N-acetyl-galactosamine specific lectin 2
chr11_-_34783850 1.18 ENSMUST00000093193.5
ENSMUST00000101365.2
dedicator of cyto-kinesis 2
chr15_-_78572754 1.17 ENSMUST00000043214.6
RAS-related C3 botulinum substrate 2
chr14_+_75131499 1.16 ENSMUST00000125833.1
ENSMUST00000124499.1
lymphocyte cytosolic protein 1
chr16_-_36642742 1.15 ENSMUST00000135280.1
CD86 antigen
chr2_-_166155624 1.13 ENSMUST00000109249.2
sulfatase 2
chr5_-_137858034 1.13 ENSMUST00000110978.2
paired immunoglobin-like type 2 receptor beta 1
chr1_-_171059390 1.13 ENSMUST00000164044.1
ENSMUST00000169017.1
Fc receptor, IgG, low affinity III
chr11_-_70812539 1.12 ENSMUST00000074572.6
ENSMUST00000108534.2
SLP adaptor and CSK interacting membrane protein
chr11_+_82045705 1.09 ENSMUST00000021011.2
chemokine (C-C motif) ligand 7
chrX_-_106603677 1.08 ENSMUST00000113480.1
cysteinyl leukotriene receptor 1
chr11_+_46810792 1.07 ENSMUST00000068877.6
T cell immunoglobulin and mucin domain containing 4
chr6_+_29529277 1.06 ENSMUST00000163511.1
interferon regulatory factor 5
chr2_-_166155272 1.03 ENSMUST00000088086.3
sulfatase 2
chr6_-_136941694 0.99 ENSMUST00000032344.5
Rho, GDP dissociation inhibitor (GDI) beta
chr2_+_24345282 0.98 ENSMUST00000114485.2
interleukin 1 receptor antagonist
chr4_+_130913120 0.98 ENSMUST00000151698.1
lysosomal-associated protein transmembrane 5
chr16_-_22657165 0.94 ENSMUST00000089925.3
diacylglycerol kinase, gamma
chr5_+_149265035 0.93 ENSMUST00000130144.1
ENSMUST00000071130.3
arachidonate 5-lipoxygenase activating protein
chr16_+_5007283 0.92 ENSMUST00000184439.1
small integral membrane protein 22
chr15_-_83033294 0.92 ENSMUST00000100377.4
Nfat activating molecule with ITAM motif 1
chr15_+_103453782 0.91 ENSMUST00000047405.7
NCK associated protein 1 like
chr4_+_130913264 0.89 ENSMUST00000156225.1
ENSMUST00000156742.1
lysosomal-associated protein transmembrane 5
chr3_-_59210881 0.89 ENSMUST00000040622.1
purinergic receptor P2Y, G-protein coupled 13
chr1_-_170927567 0.88 ENSMUST00000046322.7
ENSMUST00000159171.1
Fc receptor-like A
chr2_+_145934800 0.88 ENSMUST00000138774.1
ENSMUST00000152515.1
ENSMUST00000130168.1
ENSMUST00000133433.1
ENSMUST00000118002.1
RIKEN cDNA 4930529M08 gene
chr1_-_171234290 0.87 ENSMUST00000079957.6
Fc receptor, IgE, high affinity I, gamma polypeptide
chr4_-_43454563 0.86 ENSMUST00000107926.1
CD72 antigen
chr14_+_67745229 0.85 ENSMUST00000111095.2
gonadotropin releasing hormone 1
chr11_+_70166623 0.84 ENSMUST00000102571.3
ENSMUST00000178945.1
ENSMUST00000000327.6
C-type lectin domain family 10, member A
chr7_-_126704179 0.80 ENSMUST00000106364.1
coronin, actin binding protein 1A
chr6_+_137410721 0.79 ENSMUST00000167002.1
protein tyrosine phosphatase, receptor type, O
chr12_+_98268626 0.78 ENSMUST00000075072.4
G-protein coupled receptor 65
chr8_+_72189613 0.78 ENSMUST00000072097.6
hematopoietic SH2 domain containing
chr6_-_124733121 0.78 ENSMUST00000112484.3
protein tyrosine phosphatase, non-receptor type 6
chr16_-_22439719 0.75 ENSMUST00000079601.6
ets variant gene 5
chr11_-_17008647 0.75 ENSMUST00000102881.3
pleckstrin
chr3_-_95142346 0.75 ENSMUST00000013851.3
tumor necrosis factor, alpha-induced protein 8-like 2
chr8_-_88636117 0.72 ENSMUST00000034087.7
sorting nexin 20
chr6_-_136941494 0.72 ENSMUST00000111892.1
Rho, GDP dissociation inhibitor (GDI) beta
chr13_+_30749226 0.72 ENSMUST00000021784.2
ENSMUST00000110307.1
interferon regulatory factor 4
chr9_+_124102110 0.71 ENSMUST00000168841.1
ENSMUST00000055918.6
chemokine (C-C motif) receptor 2
chr13_+_102693522 0.71 ENSMUST00000022124.3
ENSMUST00000171267.1
ENSMUST00000167144.1
ENSMUST00000170878.1
CD180 antigen
chr11_-_58330319 0.71 ENSMUST00000065533.2
predicted gene 9900
chr4_-_43454582 0.70 ENSMUST00000107925.1
CD72 antigen
chr8_+_94923687 0.70 ENSMUST00000153448.1
ENSMUST00000074570.3
ENSMUST00000166802.1
G protein-coupled receptor 114
chrX_+_109196750 0.69 ENSMUST00000139259.1
ENSMUST00000060013.3
predicted gene 6377
chr2_+_43555321 0.68 ENSMUST00000028223.2
kynureninase (L-kynurenine hydrolase)
chr17_+_57279094 0.68 ENSMUST00000169220.2
ENSMUST00000005889.9
ENSMUST00000112870.4
vav 1 oncogene
chr5_+_86071734 0.67 ENSMUST00000031171.7
signal transducing adaptor family member 1
chr13_+_20794119 0.66 ENSMUST00000021757.3
acyloxyacyl hydrolase
chr7_-_126704736 0.66 ENSMUST00000131415.1
coronin, actin binding protein 1A
chr10_+_51480632 0.64 ENSMUST00000102894.3
ENSMUST00000105482.1
ENSMUST00000105481.1
glycoprotein 49 A
leukocyte immunoglobulin-like receptor, subfamily B, member 4
chr1_-_130729249 0.64 ENSMUST00000171479.1
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 2
chr9_+_106222598 0.63 ENSMUST00000062241.9
toll-like receptor 9
chr7_-_126704522 0.63 ENSMUST00000135087.1
coronin, actin binding protein 1A
chr7_+_45705088 0.63 ENSMUST00000080885.3
D site albumin promoter binding protein
chr15_-_102524615 0.63 ENSMUST00000023814.7
neuropeptide FF-amide peptide precursor
chr1_+_171767123 0.62 ENSMUST00000015460.4
signaling lymphocytic activation molecule family member 1
chr1_+_16688405 0.62 ENSMUST00000026881.4
lymphocyte antigen 96
chr17_+_34240015 0.61 ENSMUST00000173764.1
histocompatibility 2, O region beta locus
chr16_-_36666067 0.61 ENSMUST00000089620.4
CD86 antigen
chr5_+_57718021 0.61 ENSMUST00000094783.3
ENSMUST00000068110.7
protocadherin 7
chr6_-_83121385 0.60 ENSMUST00000146328.1
ENSMUST00000113936.3
ENSMUST00000032111.4
WW domain binding protein 1
chr1_-_149961230 0.58 ENSMUST00000070200.8
phospholipase A2, group IVA (cytosolic, calcium-dependent)
chr10_+_75893398 0.58 ENSMUST00000009236.4
Der1-like domain family, member 3
chr5_-_24601961 0.57 ENSMUST00000030791.7
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
chr2_-_52558539 0.56 ENSMUST00000102760.3
ENSMUST00000102761.2
calcium channel, voltage-dependent, beta 4 subunit
chr17_-_35172608 0.55 ENSMUST00000173106.1
allograft inflammatory factor 1
chr3_-_89387132 0.54 ENSMUST00000107433.1
zinc finger and BTB domain containing 7B
chrX_-_48454152 0.53 ENSMUST00000114958.1
E74-like factor 4 (ets domain transcription factor)
chr2_+_145934776 0.51 ENSMUST00000126415.1
ENSMUST00000116398.1
RIKEN cDNA 4930529M08 gene
chr16_+_36934976 0.51 ENSMUST00000023531.8
hematopoietic cell specific Lyn substrate 1
chr7_+_43408187 0.51 ENSMUST00000005592.6
sialic acid binding Ig-like lectin G
chr3_+_106721672 0.51 ENSMUST00000098750.2
ENSMUST00000130105.1
ligand dependent nuclear receptor interacting factor 1
chr12_+_105784694 0.48 ENSMUST00000109901.2
ENSMUST00000168186.1
ENSMUST00000163473.1
ENSMUST00000170540.1
ENSMUST00000166735.1
ENSMUST00000170002.1
poly (A) polymerase alpha
chr3_+_106721893 0.48 ENSMUST00000106736.2
ENSMUST00000154973.1
ENSMUST00000131330.1
ENSMUST00000150513.1
ligand dependent nuclear receptor interacting factor 1
chr8_-_54529951 0.48 ENSMUST00000067476.8
signal peptidase complex subunit 3 homolog (S. cerevisiae)
chr1_-_170927540 0.48 ENSMUST00000162136.1
ENSMUST00000162887.1
Fc receptor-like A
chr7_+_99535439 0.48 ENSMUST00000098266.2
ENSMUST00000179755.1
arrestin, beta 1
chr5_-_116024475 0.46 ENSMUST00000111999.1
protein kinase, AMP-activated, beta 1 non-catalytic subunit
chr10_+_130322845 0.46 ENSMUST00000042586.8
thymocyte expressed, positive selection associated 1
chr2_+_120463566 0.45 ENSMUST00000028749.7
ENSMUST00000110721.1
calpain 3
chr12_-_78980758 0.45 ENSMUST00000174072.1
transmembrane protein 229B
chr17_-_46645128 0.45 ENSMUST00000003642.6
kinesin light chain 4
chr15_-_13173607 0.44 ENSMUST00000036439.4
cadherin 6
chr3_+_87435820 0.44 ENSMUST00000178261.1
ENSMUST00000049926.8
ENSMUST00000166297.1
Fc receptor-like 5
chr3_-_96293953 0.44 ENSMUST00000029748.3
Fc receptor, IgG, high affinity I
chr4_-_136886187 0.43 ENSMUST00000046384.8
complement component 1, q subcomponent, beta polypeptide
chr16_-_22657182 0.43 ENSMUST00000023578.7
diacylglycerol kinase, gamma
chr1_+_87620334 0.43 ENSMUST00000042275.8
ENSMUST00000168783.1
inositol polyphosphate-5-phosphatase D
chr9_+_124101944 0.42 ENSMUST00000171719.1
chemokine (C-C motif) receptor 2
chrX_+_42149534 0.42 ENSMUST00000127618.1
stromal antigen 2
chr19_-_40994133 0.42 ENSMUST00000117695.1
B cell linker
chr10_-_127121125 0.41 ENSMUST00000164259.1
ENSMUST00000080975.4
amplified in osteosarcoma
chrX_+_107089234 0.41 ENSMUST00000118666.1
ENSMUST00000053375.3
purinergic receptor P2Y, G-protein coupled 10
chr19_-_11336107 0.41 ENSMUST00000056035.2
ENSMUST00000067532.4
membrane-spanning 4-domains, subfamily A, member 7
chr7_-_29232478 0.40 ENSMUST00000085818.4
potassium inwardly-rectifying channel, subfamily K, member 6
chr7_-_80387935 0.40 ENSMUST00000080932.6
feline sarcoma oncogene
chr3_+_83766300 0.39 ENSMUST00000029625.7
secreted frizzled-related protein 2
chr17_+_20945311 0.39 ENSMUST00000007708.7
protein phosphatase 2 (formerly 2A), regulatory subunit A (PR 65), alpha isoform
chr11_+_44400060 0.38 ENSMUST00000102796.3
ENSMUST00000170513.1
interleukin 12b
chr2_+_22774081 0.38 ENSMUST00000014290.8
amyloid beta (A4) precursor protein-binding, family B, member 1 interacting protein
chr2_+_156840966 0.37 ENSMUST00000109564.1
TGFB-induced factor homeobox 2
chr6_-_30304513 0.37 ENSMUST00000094543.2
ENSMUST00000102993.3
ubiquitin-conjugating enzyme E2H
chr1_-_183297008 0.36 ENSMUST00000057062.5
BRO1 domain and CAAX motif containing
chr9_-_66919646 0.36 ENSMUST00000041139.7
RAB8B, member RAS oncogene family
chr2_+_14229390 0.36 ENSMUST00000028045.2
mannose receptor, C type 1
chr6_-_88518760 0.35 ENSMUST00000032168.5
Sec61 alpha 1 subunit (S. cerevisiae)
chrX_-_38456407 0.35 ENSMUST00000074913.5
ENSMUST00000016678.7
ENSMUST00000061755.8
lysosomal-associated membrane protein 2
chr4_-_136898803 0.35 ENSMUST00000046285.5
complement component 1, q subcomponent, alpha polypeptide
chr17_-_83846769 0.35 ENSMUST00000000687.7
3-hydroxyanthranilate 3,4-dioxygenase
chr18_-_6241486 0.34 ENSMUST00000025083.7
kinesin family member 5B
chr19_+_6399857 0.34 ENSMUST00000146601.1
ENSMUST00000150713.1
RAS, guanyl releasing protein 2
chr4_-_140581774 0.34 ENSMUST00000147426.1
ENSMUST00000105797.2
Rho guanine nucleotide exchange factor (GEF) 10-like
chr19_+_6399746 0.34 ENSMUST00000113468.1
RAS, guanyl releasing protein 2
chr4_-_109476666 0.33 ENSMUST00000030284.3
ring finger protein 11
chr11_+_46454921 0.33 ENSMUST00000020668.8
hepatitis A virus cellular receptor 2
chr13_-_104228833 0.33 ENSMUST00000022226.4
peptidylprolyl isomerase domain and WD repeat containing 1
chr4_-_136892867 0.33 ENSMUST00000046332.5
complement component 1, q subcomponent, C chain
chr8_-_71395794 0.33 ENSMUST00000049184.7
Usher syndrome 1C binding protein 1
chr11_+_46454957 0.33 ENSMUST00000109229.1
hepatitis A virus cellular receptor 2
chr14_+_58075115 0.33 ENSMUST00000074654.5
fibroblast growth factor 9
chr11_-_69685537 0.32 ENSMUST00000018896.7
tumor necrosis factor (ligand) superfamily, member 13
chr9_+_45079170 0.32 ENSMUST00000050020.6
adhesion molecule, interacts with CXADR antigen 1
chrX_+_20703906 0.32 ENSMUST00000033383.2
ubiquitin specific peptidase 11
chr13_-_13393592 0.32 ENSMUST00000021738.8
G protein-coupled receptor 137B
chr9_-_53706211 0.31 ENSMUST00000068449.3
RAB39, member RAS oncogene family
chr1_+_87620306 0.31 ENSMUST00000169754.1
inositol polyphosphate-5-phosphatase D
chr12_-_84361802 0.31 ENSMUST00000021659.1
ENSMUST00000065536.2
family with sequence similarity 161, member B
chr11_+_61653259 0.31 ENSMUST00000004959.2
GRB2-related adaptor protein
chrX_+_107816477 0.31 ENSMUST00000143975.1
ENSMUST00000144695.1
ENSMUST00000167154.1
family with sequence similarity 46, member D
chr19_+_46599081 0.31 ENSMUST00000138302.2
ENSMUST00000099376.4
WW domain binding protein 1 like
chr8_+_94745590 0.31 ENSMUST00000034231.3
chemokine (C-C motif) ligand 22
chr10_+_81393610 0.30 ENSMUST00000118206.1
RIKEN cDNA 2210404O07 gene
chr19_-_6084873 0.30 ENSMUST00000160977.1
ENSMUST00000159859.1
zinc finger like protein 1
chr5_-_25498748 0.30 ENSMUST00000173174.1
lysine (K)-specific methyltransferase 2C
chr11_+_87664274 0.30 ENSMUST00000092800.5
ring finger protein 43
chr4_-_154160632 0.29 ENSMUST00000105639.3
ENSMUST00000030896.8
transformation related protein 63 regulated like
chr7_-_127588595 0.29 ENSMUST00000072155.3
predicted gene 166
chr6_-_120822680 0.29 ENSMUST00000019354.8
ATPase, H+ transporting, lysosomal V1 subunit E1
chr3_-_87263518 0.28 ENSMUST00000090986.4
Fc receptor-like S, scavenger receptor
chr1_+_171682004 0.28 ENSMUST00000015499.7
ENSMUST00000068584.5
CD48 antigen
chr12_-_78861636 0.28 ENSMUST00000021536.7
ATPase, H+ transporting, lysosomal V1 subunit D
chr2_-_130424242 0.28 ENSMUST00000089581.4
PC-esterase domain containing 1A
chr1_-_156035891 0.28 ENSMUST00000126448.1
torsin A interacting protein 1
chr2_+_126034967 0.28 ENSMUST00000110442.1
fibroblast growth factor 7
chr17_-_56584585 0.27 ENSMUST00000075510.5
scaffold attachment factor B2
chrX_-_103981242 0.27 ENSMUST00000121153.1
ENSMUST00000070705.4
ring finger protein, LIM domain interacting
chr3_-_87263703 0.26 ENSMUST00000146512.1
Fc receptor-like S, scavenger receptor
chr13_-_103334429 0.26 ENSMUST00000167058.1
ENSMUST00000164111.1
microtubule associated serine/threonine kinase family member 4
chr11_-_107470699 0.26 ENSMUST00000103064.3
phosphatidylinositol transfer protein, cytoplasmic 1
chrX_+_20848543 0.26 ENSMUST00000001155.4
ENSMUST00000122312.1
ENSMUST00000120356.1
ENSMUST00000122850.1
v-raf murine sarcoma 3611 viral oncogene homolog
chr19_-_41385070 0.26 ENSMUST00000059672.7
phosphoinositide-3-kinase adaptor protein 1
chr2_-_91070283 0.26 ENSMUST00000111436.2
ENSMUST00000073575.5
solute carrier family 39 (metal ion transporter), member 13
chr2_+_43748802 0.25 ENSMUST00000112824.1
ENSMUST00000055776.7
Rho GTPase activating protein 15
chr9_+_65032722 0.25 ENSMUST00000167773.1
dipeptidylpeptidase 8
chr8_-_106573461 0.25 ENSMUST00000073722.5
predicted pseudogene 10073
chr19_+_4154606 0.25 ENSMUST00000061086.8
protein tyrosine phosphatase, receptor type, C polypeptide-associated protein
chr19_+_12460749 0.25 ENSMUST00000081035.7
macrophage expressed gene 1
chr3_-_33844255 0.24 ENSMUST00000029222.5
coiled-coil domain containing 39
chr12_-_64965496 0.24 ENSMUST00000021331.7
kelch-like 28
chr17_-_13052280 0.24 ENSMUST00000091648.2
G protein-coupled receptor 31, D17Leh66b region
chr19_+_47865543 0.24 ENSMUST00000120645.1
glutathione S-transferase omega 2
chr18_-_35215008 0.24 ENSMUST00000091636.3
leucine rich repeat transmembrane neuronal 2
chr15_+_58510037 0.24 ENSMUST00000161028.1
fer-1-like 6 (C. elegans)
chr3_+_135825648 0.23 ENSMUST00000180196.1
solute carrier family 39 (metal ion transporter), member 8
chr2_+_24386604 0.23 ENSMUST00000166388.1
pleckstrin and Sec7 domain containing 4
chr11_+_69991633 0.22 ENSMUST00000108592.1
gamma-aminobutyric acid receptor associated protein
chr19_+_47865767 0.22 ENSMUST00000056159.4
glutathione S-transferase omega 2
chr2_-_91070180 0.21 ENSMUST00000153367.1
ENSMUST00000079976.3
solute carrier family 39 (metal ion transporter), member 13
chr3_-_97868191 0.21 ENSMUST00000163531.2
phosphodiesterase 4D interacting protein (myomegalin)

Network of associatons between targets according to the STRING database.

First level regulatory network of Spib

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.6 GO:0002434 immune complex clearance(GO:0002434)
0.6 5.7 GO:0030886 negative regulation of myeloid dendritic cell activation(GO:0030886)
0.6 2.4 GO:0001805 type III hypersensitivity(GO:0001802) regulation of type III hypersensitivity(GO:0001803) positive regulation of type III hypersensitivity(GO:0001805)
0.6 1.8 GO:0002277 myeloid dendritic cell activation involved in immune response(GO:0002277)
0.6 1.8 GO:0002644 negative regulation of tolerance induction(GO:0002644)
0.5 1.6 GO:0001878 response to yeast(GO:0001878)
0.5 2.2 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.5 2.7 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.4 1.3 GO:0045660 positive regulation of neutrophil differentiation(GO:0045660)
0.4 1.5 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.3 2.1 GO:0032796 uropod organization(GO:0032796)
0.3 1.5 GO:0045347 negative regulation of MHC class II biosynthetic process(GO:0045347)
0.2 0.7 GO:0045074 interleukin-10 biosynthetic process(GO:0042091) interleukin-13 biosynthetic process(GO:0042231) regulation of interleukin-10 biosynthetic process(GO:0045074) positive regulation of interleukin-4 biosynthetic process(GO:0045404)
0.2 1.9 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.2 0.9 GO:0002540 leukotriene production involved in inflammatory response(GO:0002540)
0.2 0.7 GO:0010760 negative regulation of macrophage chemotaxis(GO:0010760) regulation of macrophage colony-stimulating factor signaling pathway(GO:1902226) regulation of response to macrophage colony-stimulating factor(GO:1903969) regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903972)
0.2 1.7 GO:1901164 negative regulation of trophoblast cell migration(GO:1901164)
0.2 1.3 GO:0070944 neutrophil mediated killing of bacterium(GO:0070944)
0.2 0.6 GO:0034165 positive regulation of interleukin-18 production(GO:0032741) positive regulation of toll-like receptor 9 signaling pathway(GO:0034165)
0.2 0.7 GO:0045659 regulation of neutrophil differentiation(GO:0045658) negative regulation of neutrophil differentiation(GO:0045659)
0.2 0.8 GO:2000354 regulation of ovarian follicle development(GO:2000354)
0.2 0.8 GO:0051902 negative regulation of mitochondrial depolarization(GO:0051902)
0.2 0.9 GO:0002248 connective tissue replacement involved in inflammatory response wound healing(GO:0002248)
0.2 0.6 GO:0002587 negative regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002587)
0.2 0.9 GO:0001866 NK T cell proliferation(GO:0001866)
0.2 0.5 GO:0070315 G1 to G0 transition involved in cell differentiation(GO:0070315)
0.2 0.8 GO:0070560 negative regulation of inositol phosphate biosynthetic process(GO:0010920) protein secretion by platelet(GO:0070560)
0.1 1.2 GO:0060753 regulation of mast cell chemotaxis(GO:0060753)
0.1 0.7 GO:0033277 abortive mitotic cell cycle(GO:0033277)
0.1 0.5 GO:0014900 regulation of muscle hyperplasia(GO:0014738) muscle hyperplasia(GO:0014900)
0.1 0.9 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.1 0.8 GO:0003105 negative regulation of glomerular filtration(GO:0003105)
0.1 0.4 GO:2000040 Wnt signaling pathway involved in somitogenesis(GO:0090244) regulation of planar cell polarity pathway involved in axis elongation(GO:2000040) negative regulation of planar cell polarity pathway involved in axis elongation(GO:2000041)
0.1 0.4 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754) meiotic cell cycle process involved in oocyte maturation(GO:1903537) regulation of meiotic cell cycle process involved in oocyte maturation(GO:1903538)
0.1 0.4 GO:0019442 tryptophan catabolic process to acetyl-CoA(GO:0019442)
0.1 0.8 GO:0098728 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.1 0.6 GO:0032497 detection of lipopolysaccharide(GO:0032497)
0.1 0.4 GO:0071211 protein targeting to vacuole involved in autophagy(GO:0071211)
0.1 0.3 GO:0002426 immunoglobulin production in mucosal tissue(GO:0002426)
0.1 0.6 GO:0003219 cardiac right ventricle formation(GO:0003219)
0.1 2.9 GO:0001773 myeloid dendritic cell activation(GO:0001773)
0.1 1.0 GO:1904153 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.1 0.6 GO:2001280 positive regulation of prostaglandin biosynthetic process(GO:0031394) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.1 0.3 GO:0061033 secretion by lung epithelial cell involved in lung growth(GO:0061033)
0.1 0.4 GO:0050859 negative regulation of B cell receptor signaling pathway(GO:0050859)
0.1 0.4 GO:0060075 regulation of resting membrane potential(GO:0060075)
0.1 0.5 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.1 0.5 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.1 0.5 GO:0090487 toxin catabolic process(GO:0009407) secondary metabolite catabolic process(GO:0090487)
0.1 0.6 GO:0070253 somatostatin secretion(GO:0070253)
0.1 1.1 GO:0071361 cellular response to ethanol(GO:0071361)
0.1 0.3 GO:1905150 stress granule disassembly(GO:0035617) plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386) regulation of voltage-gated sodium channel activity(GO:1905150)
0.1 1.0 GO:0032494 response to peptidoglycan(GO:0032494)
0.1 1.2 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.1 0.2 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.1 0.3 GO:0034154 toll-like receptor 7 signaling pathway(GO:0034154)
0.1 0.4 GO:0002291 T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:0002291)
0.1 0.6 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.1 0.2 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.1 0.2 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.1 0.4 GO:0039019 pronephric nephron development(GO:0039019)
0.1 0.3 GO:0046874 quinolinate metabolic process(GO:0046874)
0.1 0.5 GO:0035878 nail development(GO:0035878)
0.1 0.3 GO:1900095 regulation of dosage compensation by inactivation of X chromosome(GO:1900095)
0.1 0.6 GO:1903301 positive regulation of glucokinase activity(GO:0033133) positive regulation of hexokinase activity(GO:1903301)
0.1 0.6 GO:0019227 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.1 0.4 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.3 GO:0045650 negative regulation of macrophage differentiation(GO:0045650)
0.0 1.4 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.4 GO:0045046 peroxisomal membrane transport(GO:0015919) protein import into peroxisome membrane(GO:0045046)
0.0 0.9 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 1.2 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.0 0.1 GO:2000812 regulation of barbed-end actin filament capping(GO:2000812)
0.0 0.9 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
0.0 1.3 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.1 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.0 0.5 GO:0030238 male sex determination(GO:0030238)
0.0 0.2 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.0 1.1 GO:0002437 inflammatory response to antigenic stimulus(GO:0002437)
0.0 0.5 GO:0006465 signal peptide processing(GO:0006465)
0.0 0.3 GO:0071763 nuclear membrane organization(GO:0071763)
0.0 0.1 GO:0090383 phagosome acidification(GO:0090383)
0.0 0.1 GO:0010808 positive regulation of synaptic vesicle priming(GO:0010808)
0.0 0.1 GO:0035973 aggrephagy(GO:0035973)
0.0 0.7 GO:0045954 positive regulation of natural killer cell mediated cytotoxicity(GO:0045954)
0.0 0.2 GO:0010897 negative regulation of triglyceride catabolic process(GO:0010897)
0.0 0.1 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.0 0.8 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 0.2 GO:0002361 CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361)
0.0 0.3 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.0 0.2 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.4 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0 0.1 GO:0010847 regulation of chromatin assembly(GO:0010847)
0.0 0.4 GO:0038092 nodal signaling pathway(GO:0038092)
0.0 0.3 GO:0071501 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.0 0.4 GO:0071353 cellular response to interleukin-4(GO:0071353)
0.0 0.2 GO:0033299 secretion of lysosomal enzymes(GO:0033299)
0.0 0.0 GO:0002551 mast cell chemotaxis(GO:0002551) mast cell migration(GO:0097531)
0.0 0.1 GO:0061146 Peyer's patch morphogenesis(GO:0061146)
0.0 0.1 GO:0060124 negative regulation of cardiac muscle adaptation(GO:0010616) positive regulation of growth hormone secretion(GO:0060124)
0.0 0.2 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 0.1 GO:1990564 protein polyufmylation(GO:1990564) protein K69-linked ufmylation(GO:1990592)
0.0 0.3 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.7 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 0.1 GO:1902916 positive regulation of protein polyubiquitination(GO:1902916)
0.0 0.1 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.0 0.0 GO:0042539 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.0 1.1 GO:0050728 negative regulation of inflammatory response(GO:0050728)
0.0 0.4 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 3.9 GO:0019221 cytokine-mediated signaling pathway(GO:0019221)
0.0 0.3 GO:0098868 endochondral bone growth(GO:0003416) bone growth(GO:0098868)
0.0 0.1 GO:0045623 negative regulation of CD4-positive, alpha-beta T cell differentiation(GO:0043371) negative regulation of T-helper cell differentiation(GO:0045623)
0.0 0.0 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973) positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
0.0 0.1 GO:0033089 positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0036019 endolysosome(GO:0036019)
0.2 1.2 GO:0005826 actomyosin contractile ring(GO:0005826)
0.2 1.6 GO:0043020 NADPH oxidase complex(GO:0043020)
0.1 8.9 GO:0001772 immunological synapse(GO:0001772)
0.1 0.4 GO:0097636 platelet dense granule membrane(GO:0031088) intrinsic component of autophagosome membrane(GO:0097636) integral component of autophagosome membrane(GO:0097637)
0.1 0.8 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.1 0.6 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.1 0.7 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.1 1.3 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.1 0.6 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.1 1.7 GO:0001891 phagocytic cup(GO:0001891)
0.1 0.5 GO:0005787 signal peptidase complex(GO:0005787)
0.1 0.2 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.1 0.2 GO:0099631 postsynaptic endocytic zone cytoplasmic component(GO:0099631)
0.1 0.4 GO:0000835 ER ubiquitin ligase complex(GO:0000835) Hrd1p ubiquitin ligase complex(GO:0000836)
0.1 0.6 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.6 GO:0031209 SCAR complex(GO:0031209)
0.0 0.4 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.6 GO:0071564 npBAF complex(GO:0071564)
0.0 0.4 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.1 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.5 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.1 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.0 0.5 GO:0031143 pseudopodium(GO:0031143)
0.0 0.1 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.0 0.1 GO:0098831 presynaptic active zone cytoplasmic component(GO:0098831)
0.0 0.4 GO:0051286 cell tip(GO:0051286)
0.0 0.7 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 7.1 GO:0009897 external side of plasma membrane(GO:0009897)
0.0 0.3 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.3 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.2 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.2 GO:0017119 Golgi transport complex(GO:0017119)
0.0 1.1 GO:0005581 collagen trimer(GO:0005581)
0.0 0.2 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.1 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.0 0.2 GO:0000159 protein phosphatase type 2A complex(GO:0000159)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.7 GO:0045352 interleukin-1, Type II receptor binding(GO:0005151) interleukin-1 receptor antagonist activity(GO:0005152) interleukin-1 Type I receptor antagonist activity(GO:0045352) interleukin-1 Type II receptor antagonist activity(GO:0045353)
0.6 3.0 GO:0019770 IgG receptor activity(GO:0019770)
0.4 0.9 GO:0019864 IgG binding(GO:0019864)
0.4 2.2 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.4 1.1 GO:0035717 chemokine (C-C motif) ligand 7 binding(GO:0035717)
0.4 1.1 GO:0004974 leukotriene receptor activity(GO:0004974)
0.3 0.9 GO:0004051 arachidonate 5-lipoxygenase activity(GO:0004051)
0.3 1.1 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.3 1.6 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.2 0.7 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.2 1.7 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.2 0.5 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
0.2 0.5 GO:0050610 oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor(GO:0016672) oxidoreductase activity, acting on phosphorus or arsenic in donors(GO:0030613) oxidoreductase activity, acting on phosphorus or arsenic in donors, disulfide as acceptor(GO:0030614) glutathione dehydrogenase (ascorbate) activity(GO:0045174) methylarsonate reductase activity(GO:0050610)
0.1 1.5 GO:0051525 NFAT protein binding(GO:0051525)
0.1 0.6 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.1 0.7 GO:0051425 PTB domain binding(GO:0051425)
0.1 1.3 GO:0001608 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.1 2.1 GO:0032036 myosin heavy chain binding(GO:0032036)
0.1 1.4 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 0.4 GO:0016823 hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.1 0.6 GO:0045322 unmethylated CpG binding(GO:0045322)
0.1 0.7 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.1 0.6 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.1 0.6 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.1 0.5 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.1 1.2 GO:0042288 MHC class I protein binding(GO:0042288)
0.1 1.2 GO:0042608 T cell receptor binding(GO:0042608)
0.1 0.3 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.0 0.4 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.3 GO:0099609 microtubule lateral binding(GO:0099609)
0.0 1.4 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.4 GO:0030911 TPR domain binding(GO:0030911)
0.0 0.5 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.2 GO:0045131 pre-mRNA branch point binding(GO:0045131)
0.0 3.6 GO:0004896 cytokine receptor activity(GO:0004896)
0.0 0.5 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.0 0.2 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.0 0.6 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.0 0.6 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.4 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.5 GO:0031432 titin binding(GO:0031432)
0.0 0.2 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.0 0.9 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 1.6 GO:0016860 intramolecular oxidoreductase activity(GO:0016860)
0.0 0.6 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.1 GO:0071568 UFM1 transferase activity(GO:0071568)
0.0 0.2 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.8 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.5 GO:0005537 mannose binding(GO:0005537)
0.0 0.3 GO:0019825 oxygen binding(GO:0019825)
0.0 0.4 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.3 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.1 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 1.1 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.4 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 5.3 GO:0030246 carbohydrate binding(GO:0030246)
0.0 0.6 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.5 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.5 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.8 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.2 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.0 0.3 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0 0.6 GO:0016279 lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279)
0.0 0.1 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.2 GO:0052813 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0 1.0 GO:0042974 retinoic acid receptor binding(GO:0042974)
0.0 0.1 GO:0070287 ferritin receptor activity(GO:0070287)
0.0 0.6 GO:0003823 antigen binding(GO:0003823)
0.0 0.1 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.0 GO:0008384 IkappaB kinase activity(GO:0008384)
0.0 0.2 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 0.8 GO:0005179 hormone activity(GO:0005179)
0.0 1.3 GO:0097110 scaffold protein binding(GO:0097110)
0.0 0.6 GO:0050699 WW domain binding(GO:0050699)
0.0 0.1 GO:0003831 beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase activity(GO:0003831)
0.0 0.4 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.5 GO:0005109 frizzled binding(GO:0005109)
0.0 0.9 GO:0030295 protein kinase activator activity(GO:0030295)
0.0 0.3 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 0.3 GO:0005521 lamin binding(GO:0005521)
0.0 0.0 GO:0035827 rubidium ion transmembrane transporter activity(GO:0035827)
0.0 0.3 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.5 GO:0001784 phosphotyrosine binding(GO:0001784)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.1 3.7 PID BCR 5PATHWAY BCR signaling pathway
0.1 3.4 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.1 1.6 PID IL5 PATHWAY IL5-mediated signaling events
0.1 4.3 PID IL4 2PATHWAY IL4-mediated signaling events
0.1 2.5 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.1 2.6 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.1 2.5 PID IL1 PATHWAY IL1-mediated signaling events
0.0 0.6 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.8 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 1.1 PID ENDOTHELIN PATHWAY Endothelins
0.0 2.0 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.4 PID IL27 PATHWAY IL27-mediated signaling events
0.0 1.0 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 2.9 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 1.0 PID LKB1 PATHWAY LKB1 signaling events
0.0 0.5 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.4 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 1.4 PID PDGFRB PATHWAY PDGFR-beta signaling pathway
0.0 0.7 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 0.3 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.4 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.6 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.3 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.2 1.1 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.1 1.1 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.1 0.6 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.1 2.0 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.1 1.3 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.1 1.2 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.1 1.9 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.1 1.1 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.1 0.6 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.1 2.7 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.1 2.7 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.1 0.9 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.1 2.8 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.1 2.0 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.7 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 2.4 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 2.0 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 1.2 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 0.4 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 0.4 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.4 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.4 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 0.5 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.8 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 1.4 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.5 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 0.6 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.0 0.6 REACTOME ACTIVATED POINT MUTANTS OF FGFR2 Genes involved in Activated point mutants of FGFR2
0.0 0.8 REACTOME KINESINS Genes involved in Kinesins
0.0 0.5 REACTOME PROCESSING OF INTRONLESS PRE MRNAS Genes involved in Processing of Intronless Pre-mRNAs
0.0 0.5 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 2.5 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 1.1 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.3 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.0 1.6 REACTOME CELL SURFACE INTERACTIONS AT THE VASCULAR WALL Genes involved in Cell surface interactions at the vascular wall
0.0 0.4 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.1 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.3 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.7 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.3 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 0.5 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation