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2D miR_HR1_12

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Results for Pou4f1_Pou6f1

Z-value: 0.81

Motif logo

Transcription factors associated with Pou4f1_Pou6f1

Gene Symbol Gene ID Gene Info
ENSMUSG00000048349.8 POU domain, class 4, transcription factor 1
ENSMUSG00000009739.10 POU domain, class 6, transcription factor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Pou6f1mm10_v2_chr15_-_100599983_1006000390.846.2e-04Click!
Pou4f1mm10_v2_chr14_-_104467984_104468041-0.402.0e-01Click!

Activity profile of Pou4f1_Pou6f1 motif

Sorted Z-values of Pou4f1_Pou6f1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr16_-_22439570 2.17 ENSMUST00000170393.1
ets variant gene 5
chr16_-_22439719 1.78 ENSMUST00000079601.6
ets variant gene 5
chr15_-_100599983 1.53 ENSMUST00000073837.6
POU domain, class 6, transcription factor 1
chr3_+_60081861 1.28 ENSMUST00000029326.5
succinate receptor 1
chr1_-_158814469 1.14 ENSMUST00000161589.2
pappalysin 2
chr2_-_93452679 1.07 ENSMUST00000111257.1
ENSMUST00000145553.1
CD82 antigen
chr11_-_100939540 1.02 ENSMUST00000127638.1
signal transducer and activator of transcription 3
chr15_-_100599864 1.02 ENSMUST00000177247.2
ENSMUST00000177505.2
POU domain, class 6, transcription factor 1
chr19_+_32619997 0.93 ENSMUST00000025833.6
3'-phosphoadenosine 5'-phosphosulfate synthase 2
chr6_+_96115249 0.86 ENSMUST00000075080.5
family with sequence similarity 19, member A1
chr11_+_29718563 0.84 ENSMUST00000060992.5
reticulon 4
chr1_-_60043087 0.83 ENSMUST00000027172.6
islet cell autoantigen 1-like
chr13_-_18382041 0.83 ENSMUST00000139064.2
ENSMUST00000175703.2
POU domain, class 6, transcription factor 2
chr4_-_42168603 0.83 ENSMUST00000098121.3
predicted gene 13305
chr8_+_12984246 0.82 ENSMUST00000110873.3
ENSMUST00000173006.1
ENSMUST00000145067.1
mcf.2 transforming sequence-like
chr11_+_46404720 0.80 ENSMUST00000063166.5
family with sequence similarity 71, member B
chr11_-_100939457 0.76 ENSMUST00000138438.1
signal transducer and activator of transcription 3
chr18_+_37504264 0.76 ENSMUST00000052179.6
protocadherin beta 20
chr16_+_5007283 0.75 ENSMUST00000184439.1
small integral membrane protein 22
chr11_-_100939357 0.73 ENSMUST00000092671.5
ENSMUST00000103114.1
signal transducer and activator of transcription 3
chrX_-_163761323 0.70 ENSMUST00000059320.2
ring finger protein 138, retrogene 1
chr5_-_108795352 0.67 ENSMUST00000004943.1
transmembrane emp24 protein transport domain containing
chr17_+_6673610 0.66 ENSMUST00000097430.2
synaptotagmin-like 3
chr5_-_30461902 0.65 ENSMUST00000133509.1
ENSMUST00000074171.6
ENSMUST00000114747.2
ENSMUST00000144125.1
otoferlin
chr4_+_102254993 0.65 ENSMUST00000106908.2
phosphodiesterase 4B, cAMP specific
chr11_-_73324616 0.65 ENSMUST00000021119.2
aspartoacylase
chr16_-_29946499 0.64 ENSMUST00000181968.1
predicted gene, 26569
chr11_+_93098404 0.58 ENSMUST00000107859.1
ENSMUST00000042943.6
ENSMUST00000107861.1
ENSMUST00000107858.2
carbonic anhydrase 10
chr13_+_42681513 0.57 ENSMUST00000149235.1
phosphatase and actin regulator 1
chr4_+_41569775 0.56 ENSMUST00000102963.3
dynein, axonemal, intermediate chain 1
chr6_+_80018877 0.55 ENSMUST00000147663.1
ENSMUST00000128718.1
ENSMUST00000126005.1
ENSMUST00000133918.1
leucine rich repeat transmembrane neuronal 4
chr6_-_36811361 0.54 ENSMUST00000101534.1
pleiotrophin
chr7_-_45370559 0.54 ENSMUST00000003971.7
lin-7 homolog B (C. elegans)
chr6_-_131313827 0.54 ENSMUST00000049150.1
serine/threonine/tyrosine kinase 1
chr9_-_58201705 0.53 ENSMUST00000163200.1
ENSMUST00000165276.1
immunoglobulin superfamily containing leucine-rich repeat 2
chr9_-_58202281 0.53 ENSMUST00000163897.1
immunoglobulin superfamily containing leucine-rich repeat 2
chr11_+_93099284 0.52 ENSMUST00000092780.3
ENSMUST00000107863.2
carbonic anhydrase 10
chr16_+_5007306 0.52 ENSMUST00000178155.2
ENSMUST00000184256.1
ENSMUST00000185147.1
small integral membrane protein 22
chr2_+_84734050 0.52 ENSMUST00000090729.2
yippee-like 4 (Drosophila)
chr2_-_35100677 0.50 ENSMUST00000045776.4
ENSMUST00000113050.3
expressed sequence AI182371
chr14_+_25983005 0.49 ENSMUST00000049793.8
double homeobox B-like 1
chr13_-_64129305 0.48 ENSMUST00000099441.4
solute carrier family 35, member D2
chr15_-_75894474 0.48 ENSMUST00000023237.6
nicotinate phosphoribosyltransferase domain containing 1
chr9_-_26802563 0.47 ENSMUST00000162252.1
galactosidase, beta 1-like 2
chrX_+_99042581 0.47 ENSMUST00000036606.7
START domain containing 8
chr12_-_59061425 0.46 ENSMUST00000021380.8
trafficking protein particle complex 6B
chr17_+_85028347 0.45 ENSMUST00000024944.7
solute carrier family 3, member 1
chr6_+_80019008 0.45 ENSMUST00000126399.1
ENSMUST00000136421.1
leucine rich repeat transmembrane neuronal 4
chr17_-_36032682 0.45 ENSMUST00000102678.4
histocompatibility 2, T region locus 23
chr11_-_99244058 0.45 ENSMUST00000103132.3
ENSMUST00000038214.6
keratin 222
chr10_+_34483400 0.44 ENSMUST00000019913.7
ENSMUST00000170771.1
fyn-related kinase
chr6_+_125009113 0.43 ENSMUST00000054553.4
zinc finger protein 384
chr9_-_101034892 0.43 ENSMUST00000035116.5
propionyl Coenzyme A carboxylase, beta polypeptide
chr8_+_69300776 0.42 ENSMUST00000078257.6
RIKEN cDNA D130040H23 gene
chr9_-_101034857 0.41 ENSMUST00000142676.1
ENSMUST00000149322.1
propionyl Coenzyme A carboxylase, beta polypeptide
chr3_-_113574758 0.40 ENSMUST00000106540.1
amylase 1, salivary
chr11_+_98348404 0.39 ENSMUST00000078694.6
protein phosphatase 1, regulatory (inhibitor) subunit 1B
chr19_-_33392255 0.39 ENSMUST00000096114.5
ENSMUST00000163093.1
renalase, FAD-dependent amine oxidase
chr11_+_66911981 0.39 ENSMUST00000123434.2
phosphoinositide-interacting regulator of transient receptor potential channels
chr4_+_102589687 0.39 ENSMUST00000097949.4
ENSMUST00000106901.1
phosphodiesterase 4B, cAMP specific
chr4_+_152338619 0.39 ENSMUST00000030775.5
ENSMUST00000164662.1
chromodomain helicase DNA binding protein 5
chr8_-_64987646 0.39 ENSMUST00000095295.1
tripartite motif-containing 75
chr2_+_176230177 0.39 ENSMUST00000135430.1
RIKEN cDNA 2210418O10 gene
chr19_+_4081565 0.38 ENSMUST00000159593.1
calcium binding protein 2
chr6_+_42245907 0.38 ENSMUST00000031897.5
glutathione S-transferase kappa 1
chr14_+_26122609 0.38 ENSMUST00000100810.6
doubl homeobox B-like 2
chr1_-_180996145 0.37 ENSMUST00000154133.1
epoxide hydrolase 1, microsomal
chr7_-_30195046 0.37 ENSMUST00000001845.5
calpain, small subunit 1
chr12_+_58211772 0.37 ENSMUST00000110671.2
ENSMUST00000044299.2
somatostatin receptor 1
chr1_+_88166004 0.34 ENSMUST00000097659.4
UDP glucuronosyltransferase 1 family, polypeptide A5
chr9_+_38752796 0.33 ENSMUST00000074740.2
olfactory receptor 920
chr19_-_40187277 0.32 ENSMUST00000051846.6
cytochrome P450, family 2, subfamily c, polypeptide 70
chr15_-_98831498 0.31 ENSMUST00000168846.1
protein kinase, AMP-activated, gamma 1 non-catalytic subunit
chr11_+_3983636 0.31 ENSMUST00000078757.1
galactose-3-O-sulfotransferase 1
chr3_-_146108047 0.31 ENSMUST00000160285.1
WD repeat domain 63
chr3_+_28263205 0.31 ENSMUST00000159236.2
TRAF2 and NCK interacting kinase
chr10_-_125328957 0.30 ENSMUST00000063318.2
solute carrier family 16 (monocarboxylic acid transporters), member 7
chr11_+_75193783 0.30 ENSMUST00000102514.3
reticulon 4 receptor-like 1
chr11_+_3983704 0.30 ENSMUST00000063004.7
galactose-3-O-sulfotransferase 1
chr5_+_20702129 0.30 ENSMUST00000101556.4
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr9_+_113812547 0.29 ENSMUST00000166734.2
ENSMUST00000111838.2
ENSMUST00000163895.2
CLIP associating protein 2
chr11_-_50841546 0.29 ENSMUST00000109133.1
ENSMUST00000109134.1
ENSMUST00000049625.1
zinc finger protein 879
chr10_-_42478280 0.29 ENSMUST00000151747.1
lactation elevated 1
chr7_-_24333959 0.28 ENSMUST00000069562.4
tescalcin-like
chrX_-_59166080 0.28 ENSMUST00000119306.1
fibroblast growth factor 13
chr7_+_46847128 0.26 ENSMUST00000005051.4
lactate dehydrogenase A
chr14_+_26262258 0.26 ENSMUST00000100804.4
double homeobox B-like 3
chr5_-_137786681 0.26 ENSMUST00000132726.1
methylphosphate capping enzyme
chr6_+_125009232 0.26 ENSMUST00000112428.1
zinc finger protein 384
chr4_-_110287479 0.25 ENSMUST00000106598.1
ENSMUST00000102723.4
ENSMUST00000153906.1
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr1_-_24005608 0.25 ENSMUST00000027338.3
RIKEN cDNA 1110058L19 gene
chr10_-_64090265 0.25 ENSMUST00000105439.1
leucine rich repeat transmembrane neuronal 3
chr18_-_32036941 0.25 ENSMUST00000134663.1
myosin VIIB
chr3_-_86999284 0.25 ENSMUST00000063869.5
ENSMUST00000029717.2
CD1d1 antigen
chr4_-_138326234 0.24 ENSMUST00000105817.3
ENSMUST00000030536.6
PTEN induced putative kinase 1
chr11_+_87664549 0.24 ENSMUST00000121782.2
ring finger protein 43
chr6_+_125009261 0.24 ENSMUST00000112427.1
zinc finger protein 384
chr9_-_124311750 0.23 ENSMUST00000177714.1
RIKEN cDNA 2010315B03 gene
chr6_+_97991776 0.23 ENSMUST00000043628.6
microphthalmia-associated transcription factor
chr4_-_3938354 0.23 ENSMUST00000003369.3
pleiomorphic adenoma gene 1
chr5_-_70842617 0.23 ENSMUST00000031119.1
gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1
chr15_+_100870670 0.23 ENSMUST00000082209.6
sodium channel, voltage-gated, type VIII, alpha
chr2_-_168734236 0.23 ENSMUST00000109175.2
ATPase, class II, type 9A
chr4_+_150853919 0.23 ENSMUST00000073600.2
ERBB receptor feedback inhibitor 1
chr4_+_43384332 0.23 ENSMUST00000136360.1
RUN and SH3 domain containing 2
chr17_-_6621267 0.23 ENSMUST00000115772.3
transmembrane protein 181C, pseudogene
chr10_+_119992962 0.21 ENSMUST00000154238.1
glutamate receptor interacting protein 1
chr4_-_123904826 0.21 ENSMUST00000181292.1
predicted gene, 26606
chr10_-_29144194 0.21 ENSMUST00000070359.2
predicted gene 9996
chr5_-_137786651 0.21 ENSMUST00000031740.9
methylphosphate capping enzyme
chr18_+_56432116 0.21 ENSMUST00000070166.5
GRAM domain containing 3
chr6_+_41458923 0.21 ENSMUST00000031910.7
protease, serine, 1 (trypsin 1)
chr9_-_78109020 0.20 ENSMUST00000001402.7
f-box protein 9
chr8_-_25091341 0.20 ENSMUST00000125466.1
pleckstrin homology domain-containing, family A (phosphoinositide binding specific) member 2
chr10_-_24101951 0.20 ENSMUST00000170267.1
trace amine-associated receptor 8C
chr19_-_46672883 0.20 ENSMUST00000026012.7
cytochrome P450, family 17, subfamily a, polypeptide 1
chr10_+_26772477 0.20 ENSMUST00000039557.7
Rho GTPase activating protein 18
chr5_+_137350101 0.20 ENSMUST00000061244.8
Eph receptor B4
chr5_+_137350371 0.20 ENSMUST00000166239.1
ENSMUST00000111054.1
Eph receptor B4
chr5_-_44101668 0.19 ENSMUST00000087441.4
ENSMUST00000074113.6
prominin 1
chr18_+_59062282 0.19 ENSMUST00000165666.2
RIKEN cDNA A730017C20 gene
chr9_+_54538984 0.19 ENSMUST00000060242.5
ENSMUST00000118413.1
SH2 domain containing 7
chr1_+_180101144 0.19 ENSMUST00000133890.1
CDC42 binding protein kinase alpha
chr18_-_37020679 0.19 ENSMUST00000097612.2
predicted gene 10545
chr12_+_10390756 0.18 ENSMUST00000020947.5
retinol dehydrogenase 14 (all-trans and 9-cis)
chr13_+_104287855 0.18 ENSMUST00000065766.6
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 6
chr4_-_119190005 0.18 ENSMUST00000138395.1
ENSMUST00000156746.1
erythroblast membrane-associated protein
chr18_+_59062462 0.18 ENSMUST00000058633.2
ENSMUST00000175897.1
ENSMUST00000118510.1
ENSMUST00000175830.1
RIKEN cDNA A730017C20 gene
chr5_+_137350162 0.17 ENSMUST00000111055.2
Eph receptor B4
chr8_+_106935720 0.17 ENSMUST00000047425.3
syntrophin, basic 2
chr14_+_27000362 0.17 ENSMUST00000035433.8
homeobox gene expressed in ES cells
chr4_+_154964117 0.17 ENSMUST00000030931.4
ENSMUST00000070953.4
pantothenate kinase 4
chr8_-_83332416 0.17 ENSMUST00000177594.1
ENSMUST00000053902.3
ELMO/CED-12 domain containing 2
chr8_+_70539675 0.17 ENSMUST00000093454.6
elongation factor RNA polymerase II
chrX_+_106027259 0.16 ENSMUST00000113557.1
ATPase, Cu++ transporting, alpha polypeptide
chr1_+_179961110 0.16 ENSMUST00000076687.5
ENSMUST00000097450.3
CDC42 binding protein kinase alpha
chr12_+_59095653 0.16 ENSMUST00000021384.4
melanoma inhibitory activity 2
chr7_-_110061319 0.16 ENSMUST00000098110.2
expressed sequence AA474408
chr17_-_32917048 0.16 ENSMUST00000054174.7
cytochrome P450, family 4, subfamily f, polypeptide 14
chr14_+_21750525 0.16 ENSMUST00000022292.3
sterile alpha motif domain containing 8
chr13_+_75089826 0.16 ENSMUST00000022075.4
proprotein convertase subtilisin/kexin type 1
chr8_+_10006656 0.16 ENSMUST00000033892.7
tumor necrosis factor (ligand) superfamily, member 13b
chr5_-_39644634 0.15 ENSMUST00000053116.6
heparan sulfate (glucosamine) 3-O-sulfotransferase 1
chrX_+_106027300 0.15 ENSMUST00000055941.6
ATPase, Cu++ transporting, alpha polypeptide
chr18_+_7868823 0.15 ENSMUST00000171042.1
ENSMUST00000166378.1
ENSMUST00000074919.4
WW domain containing adaptor with coiled-coil
chr15_+_81811414 0.15 ENSMUST00000023024.7
thyrotroph embryonic factor
chr15_+_18818895 0.15 ENSMUST00000166873.2
cadherin 10
chr2_-_174346712 0.14 ENSMUST00000168292.1
predicted gene, 20721
chr17_-_32917320 0.14 ENSMUST00000179434.1
cytochrome P450, family 4, subfamily f, polypeptide 14
chr14_-_30353468 0.14 ENSMUST00000112249.1
calcium channel, voltage-dependent, L type, alpha 1D subunit
chr1_-_134955908 0.14 ENSMUST00000045665.6
ENSMUST00000086444.4
ENSMUST00000112163.1
protein phosphatase 1, regulatory (inhibitor) subunit 12B
chr6_+_41392356 0.14 ENSMUST00000049079.7
predicted gene 5771
chr2_+_69380431 0.14 ENSMUST00000063690.3
dehydrogenase/reductase (SDR family) member 9
chr18_-_35498856 0.14 ENSMUST00000025215.8
endoplasmic reticulum chaperone SIL1 homolog (S. cerevisiae)
chr18_-_36726730 0.14 ENSMUST00000061829.6
CD14 antigen
chr6_-_41314700 0.14 ENSMUST00000064324.5
trypsin 5
chr1_+_180945898 0.14 ENSMUST00000160508.1
ENSMUST00000160536.1
transmembrane protein 63a
chr15_-_58214882 0.14 ENSMUST00000022986.6
F-box protein 32
chr5_-_44102032 0.13 ENSMUST00000171543.1
prominin 1
chr7_-_28962265 0.13 ENSMUST00000068045.7
actinin alpha 4
chr10_-_112928974 0.13 ENSMUST00000099276.2
ataxin 7-like 3B
chr12_+_59129720 0.13 ENSMUST00000175912.1
ENSMUST00000176892.1
CTAGE family, member 5
chr1_-_132390301 0.13 ENSMUST00000132435.1
transmembrane and coiled-coil domains 2
chr10_-_42478488 0.13 ENSMUST00000041024.8
lactation elevated 1
chr3_-_96708524 0.13 ENSMUST00000029742.5
ENSMUST00000171249.1
nudix (nucleoside diphosphate linked moiety X)-type motif 17
chr8_-_117082449 0.13 ENSMUST00000098375.4
ENSMUST00000109093.2
polycystic kidney disease 1 like 2
chr7_-_133702515 0.13 ENSMUST00000153698.1
uroporphyrinogen III synthase
chr5_-_138619751 0.12 ENSMUST00000085852.4
ENSMUST00000110905.2
zinc finger protein 68
chr7_-_84679346 0.12 ENSMUST00000069537.2
ENSMUST00000178385.1
zinc finger, AN1-type domain 6
chr12_+_59129757 0.12 ENSMUST00000069430.8
ENSMUST00000177370.1
CTAGE family, member 5
chr1_-_166002591 0.12 ENSMUST00000111429.4
ENSMUST00000176800.1
POU domain, class 2, transcription factor 1
chr13_-_38960846 0.12 ENSMUST00000021870.4
solute carrier family 35, member B3
chr10_+_29143996 0.12 ENSMUST00000092629.2
SOGA family member 3
chr10_+_7589885 0.12 ENSMUST00000130590.1
ENSMUST00000135907.1
low density lipoprotein receptor-related protein 11
chr7_+_64185459 0.12 ENSMUST00000177102.2
ENSMUST00000107519.1
ENSMUST00000137650.1
ENSMUST00000032737.5
ENSMUST00000107515.1
ENSMUST00000144996.1
transient receptor potential cation channel, subfamily M, member 1
chr9_-_103222063 0.12 ENSMUST00000170904.1
transferrin
chr1_-_133661318 0.11 ENSMUST00000179598.1
ENSMUST00000027736.6
zinc finger, BED domain containing 6
zinc finger CCCH type containing 11A
chr10_-_56228636 0.11 ENSMUST00000099739.3
TBC1 domain family, member 32
chr10_+_5593718 0.11 ENSMUST00000051809.8
myc target 1
chr8_-_67974567 0.11 ENSMUST00000098696.3
ENSMUST00000038959.9
ENSMUST00000093469.4
pleckstrin and Sec7 domain containing 3
chr2_+_152669461 0.11 ENSMUST00000125366.1
ENSMUST00000109825.1
ENSMUST00000089059.2
ENSMUST00000079247.3
histocompatibility 13
chr10_+_7589788 0.10 ENSMUST00000134346.1
ENSMUST00000019931.5
low density lipoprotein receptor-related protein 11
chr14_-_79247296 0.10 ENSMUST00000161649.1
zinc finger protein 957
chr3_-_57575907 0.10 ENSMUST00000120977.1
WW domain containing transcription regulator 1
chr13_-_102958084 0.10 ENSMUST00000099202.3
ENSMUST00000172264.1
microtubule associated serine/threonine kinase family member 4
chr11_-_42182924 0.10 ENSMUST00000020707.5
ENSMUST00000132971.1
gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1
chr6_+_86404257 0.10 ENSMUST00000095752.2
ENSMUST00000130967.1
cytotoxic granule-associated RNA binding protein 1
chr19_-_7966000 0.10 ENSMUST00000182102.1
ENSMUST00000075619.4
solute carrier family 22, member 27
chr17_+_66111529 0.10 ENSMUST00000072383.6
WAS protein family homolog
chr2_+_82053222 0.10 ENSMUST00000047527.7
zinc finger protein 804A
chr11_-_4594750 0.10 ENSMUST00000109943.3
myotubularin related protein 3
chr8_-_87472576 0.09 ENSMUST00000034076.8
cerebellin 1 precursor protein
chr2_+_93452796 0.09 ENSMUST00000099693.2
ENSMUST00000162565.1
ENSMUST00000163052.1
predicted gene 10804
chr5_+_121802230 0.09 ENSMUST00000162995.1
ataxin 2
chr10_-_62899118 0.09 ENSMUST00000174189.1
tet methylcytosine dioxygenase 1
chr13_-_65205716 0.09 ENSMUST00000037372.7
NLR family, pyrin domain containing 4F
chr7_-_28962223 0.09 ENSMUST00000127210.1
actinin alpha 4
chr7_-_99980431 0.09 ENSMUST00000080817.4
ring finger protein 169
chr1_+_180109192 0.09 ENSMUST00000143176.1
ENSMUST00000135056.1
CDC42 binding protein kinase alpha
chr2_-_77519565 0.09 ENSMUST00000111830.2
zinc finger protein 385B

Network of associatons between targets according to the STRING database.

First level regulatory network of Pou4f1_Pou6f1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 3.9 GO:0098728 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.6 2.5 GO:1902724 positive regulation of skeletal muscle satellite cell proliferation(GO:1902724) positive regulation of growth factor dependent skeletal muscle satellite cell proliferation(GO:1902728)
0.2 0.9 GO:0000103 sulfate assimilation(GO:0000103)
0.2 0.7 GO:0042414 epinephrine metabolic process(GO:0042414)
0.1 0.8 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.1 0.5 GO:1904395 positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395)
0.1 0.6 GO:2000523 regulation of T cell costimulation(GO:2000523) positive regulation of T cell costimulation(GO:2000525)
0.1 0.5 GO:0002489 antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway(GO:0002488) antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent(GO:0002489) positive regulation of CD8-positive, alpha-beta T cell proliferation(GO:2000566)
0.1 0.3 GO:0072139 glomerular parietal epithelial cell differentiation(GO:0072139)
0.1 0.5 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.1 0.6 GO:0006083 acetate metabolic process(GO:0006083)
0.1 0.4 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.1 1.0 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1 0.2 GO:0045404 positive regulation of interleukin-4 biosynthetic process(GO:0045404) antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.1 0.3 GO:1901475 pyruvate transmembrane transport(GO:1901475)
0.1 0.2 GO:1902396 protein localization to bicellular tight junction(GO:1902396)
0.1 1.3 GO:1901629 regulation of presynaptic membrane organization(GO:1901629)
0.1 0.2 GO:1903384 neuron intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:0036482) positive regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902958) regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway(GO:1903383) negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway(GO:1903384)
0.1 0.2 GO:0009414 response to water deprivation(GO:0009414)
0.1 0.3 GO:0019244 lactate biosynthetic process from pyruvate(GO:0019244)
0.1 0.2 GO:0031296 B cell costimulation(GO:0031296)
0.1 0.3 GO:0007256 activation of JNKK activity(GO:0007256)
0.0 0.2 GO:1904970 brush border assembly(GO:1904970)
0.0 0.4 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.0 0.3 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0 0.1 GO:0071725 response to triacyl bacterial lipopeptide(GO:0071725) cellular response to triacyl bacterial lipopeptide(GO:0071727)
0.0 0.4 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.2 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.0 0.3 GO:0045196 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.0 0.2 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.0 0.2 GO:0042536 negative regulation of tumor necrosis factor biosynthetic process(GO:0042536) negative regulation of cardiac muscle hypertrophy in response to stress(GO:1903243)
0.0 0.1 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.0 0.1 GO:1904211 membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211)
0.0 0.1 GO:0014854 response to inactivity(GO:0014854) response to muscle inactivity(GO:0014870) response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.0 0.4 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.0 0.5 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 0.1 GO:0006780 uroporphyrinogen III biosynthetic process(GO:0006780)
0.0 0.1 GO:0071894 histone H2B conserved C-terminal lysine ubiquitination(GO:0071894)
0.0 0.3 GO:0052696 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.0 0.3 GO:0035562 negative regulation of chromatin binding(GO:0035562)
0.0 0.4 GO:0034312 diol biosynthetic process(GO:0034312)
0.0 0.6 GO:0016082 synaptic vesicle priming(GO:0016082)
0.0 0.2 GO:0030916 otic vesicle formation(GO:0030916)
0.0 0.2 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.3 GO:0048681 negative regulation of axon regeneration(GO:0048681)
0.0 0.1 GO:0048880 sensory system development(GO:0048880)
0.0 0.8 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.0 0.1 GO:0042939 glutathione transport(GO:0034635) tripeptide transport(GO:0042939)
0.0 0.3 GO:0042448 progesterone metabolic process(GO:0042448)
0.0 0.2 GO:1902004 positive regulation of beta-amyloid formation(GO:1902004)
0.0 0.7 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.1 GO:0072307 metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
0.0 0.2 GO:0044336 canonical Wnt signaling pathway involved in negative regulation of apoptotic process(GO:0044336)
0.0 0.1 GO:0023016 signal transduction by trans-phosphorylation(GO:0023016)
0.0 0.4 GO:0040023 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.0 0.1 GO:0045014 carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
0.0 0.1 GO:0035106 operant conditioning(GO:0035106)
0.0 0.1 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.0 0.1 GO:0090310 negative regulation of methylation-dependent chromatin silencing(GO:0090310)
0.0 1.0 GO:0045773 positive regulation of axon extension(GO:0045773)
0.0 0.1 GO:0097460 positive regulation of oligodendrocyte progenitor proliferation(GO:0070447) ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
0.0 0.1 GO:0030046 parallel actin filament bundle assembly(GO:0030046)
0.0 0.5 GO:0033006 regulation of mast cell activation involved in immune response(GO:0033006) regulation of mast cell degranulation(GO:0043304)
0.0 0.0 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.0 0.4 GO:0048266 behavioral response to pain(GO:0048266)
0.0 0.2 GO:0060252 positive regulation of glial cell proliferation(GO:0060252)
0.0 0.2 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.0 GO:0015851 nucleobase transport(GO:0015851) pyrimidine nucleobase transport(GO:0015855)
0.0 0.1 GO:0015747 urate transport(GO:0015747)
0.0 0.3 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.1 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.1 0.3 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.1 0.3 GO:0071914 prominosome(GO:0071914)
0.1 0.7 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.0 1.0 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.5 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.5 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 0.8 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 0.1 GO:0035841 new growing cell tip(GO:0035841)
0.0 0.5 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.2 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 1.0 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.1 GO:0098553 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.0 0.1 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.3 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.3 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.4 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.3 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.3 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.1 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.2 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.1 GO:0097165 nuclear stress granule(GO:0097165)
0.0 0.2 GO:0031143 pseudopodium(GO:0031143)
0.0 0.1 GO:1990712 dense body(GO:0097433) HFE-transferrin receptor complex(GO:1990712)
0.0 2.0 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 2.0 GO:0090575 RNA polymerase II transcription factor complex(GO:0090575)
0.0 0.7 GO:0019897 extrinsic component of plasma membrane(GO:0019897)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0004658 propionyl-CoA carboxylase activity(GO:0004658)
0.3 2.5 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.2 0.6 GO:0019807 aspartoacylase activity(GO:0019807)
0.2 0.5 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.2 0.6 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733)
0.1 0.4 GO:0031752 D3 dopamine receptor binding(GO:0031750) D5 dopamine receptor binding(GO:0031752)
0.1 0.3 GO:0052871 tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871)
0.1 0.4 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
0.1 0.5 GO:0004565 beta-galactosidase activity(GO:0004565)
0.1 0.5 GO:0097016 L27 domain binding(GO:0097016)
0.1 0.3 GO:0043682 copper-exporting ATPase activity(GO:0004008) copper-transporting ATPase activity(GO:0043682)
0.1 0.3 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.1 0.4 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.1 0.4 GO:0004994 somatostatin receptor activity(GO:0004994)
0.1 0.3 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.1 0.4 GO:0071723 lipopeptide binding(GO:0071723)
0.1 0.4 GO:0004556 alpha-amylase activity(GO:0004556)
0.1 0.5 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.0 0.9 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.8 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.3 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 0.1 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.0 0.7 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.5 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.0 0.3 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.0 0.2 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.1 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.0 0.2 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.4 GO:0005549 odorant binding(GO:0005549)
0.0 0.4 GO:0008392 arachidonic acid epoxygenase activity(GO:0008392)
0.0 0.2 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.0 0.7 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.6 GO:0005003 ephrin receptor activity(GO:0005003)
0.0 0.9 GO:0070566 adenylyltransferase activity(GO:0070566)
0.0 0.1 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.0 1.0 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.2 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.1 GO:0004335 galactokinase activity(GO:0004335)
0.0 0.1 GO:0015182 L-asparagine transmembrane transporter activity(GO:0015182)
0.0 0.2 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.3 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.1 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.0 0.3 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.0 0.3 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.1 GO:0086007 voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007)
0.0 0.5 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 0.6 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.1 GO:0072510 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.0 0.0 GO:0001032 RNA polymerase III type 3 promoter DNA binding(GO:0001032)
0.0 1.0 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.4 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.1 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.7 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.2 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.1 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.2 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.2 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.0 0.1 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.2 GO:0008106 alcohol dehydrogenase (NADP+) activity(GO:0008106)
0.0 0.2 GO:0031402 sodium ion binding(GO:0031402)
0.0 0.3 GO:0015020 glucuronosyltransferase activity(GO:0015020)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 6.3 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.5 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.8 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 0.6 PID EPHRINB REV PATHWAY Ephrin B reverse signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.5 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.1 0.9 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 1.1 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.8 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.3 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 1.2 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.3 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.2 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 0.3 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.2 REACTOME PEPTIDE HORMONE BIOSYNTHESIS Genes involved in Peptide hormone biosynthesis
0.0 0.6 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.5 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.3 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.0 0.2 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.6 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.5 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.1 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 0.5 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane