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2D miR_HR1_12

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Results for Thrb

Z-value: 0.41

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Transcription factors associated with Thrb

Gene Symbol Gene ID Gene Info
ENSMUSG00000021779.10 thyroid hormone receptor beta

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Thrbmm10_v2_chr14_+_17660956_176609630.195.5e-01Click!

Activity profile of Thrb motif

Sorted Z-values of Thrb motif

Promoter Log-likelihood Transcript Gene Gene Info
chr2_+_119167758 0.69 ENSMUST00000057454.3
GTP cyclohydrolase I feedback regulator
chr1_-_52499980 0.50 ENSMUST00000164747.1
Ngfi-A binding protein 1
chr2_+_152962485 0.41 ENSMUST00000099197.2
ENSMUST00000103155.3
tubulin tyrosine ligase-like family, member 9
chr3_+_67374091 0.37 ENSMUST00000077916.5
myeloid leukemia factor 1
chr14_-_7994563 0.36 ENSMUST00000026315.7
deoxyribonuclease 1-like 3
chr3_+_14863495 0.32 ENSMUST00000029076.4
carbonic anhydrase 3
chr3_+_67374116 0.31 ENSMUST00000061322.8
myeloid leukemia factor 1
chr16_-_17144415 0.30 ENSMUST00000115709.1
coiled-coil domain containing 116
chr7_+_101896817 0.29 ENSMUST00000143835.1
anaphase prompoting complex C subunit 15
chr15_-_103251465 0.26 ENSMUST00000133600.1
ENSMUST00000134554.1
ENSMUST00000156927.1
ENSMUST00000149111.1
ENSMUST00000132836.1
nuclear factor, erythroid derived 2
chr1_+_87214286 0.26 ENSMUST00000113231.3
eukaryotic translation initiation factor 4E member 2
chr5_+_108065696 0.25 ENSMUST00000172045.1
metal response element binding transcription factor 2
chr2_-_105399286 0.21 ENSMUST00000006128.6
reticulocalbin 1
chr7_+_25897620 0.21 ENSMUST00000072438.6
ENSMUST00000005477.5
cytochrome P450, family 2, subfamily b, polypeptide 10
chr9_+_44673227 0.20 ENSMUST00000034609.4
ENSMUST00000071219.5
trehalase (brush-border membrane glycoprotein)
chr17_+_56162477 0.20 ENSMUST00000077788.6
tumor necrosis factor, alpha-induced protein 8-like 1
chr10_+_81176631 0.20 ENSMUST00000047864.9
eukaryotic translation elongation factor 2
chr9_+_95857597 0.16 ENSMUST00000034980.7
ataxia telangiectasia and Rad3 related
chr7_-_105600103 0.14 ENSMUST00000033185.8
hemopexin
chr1_+_87213924 0.13 ENSMUST00000113230.1
ENSMUST00000123735.1
eukaryotic translation initiation factor 4E member 2
chr11_-_113709520 0.11 ENSMUST00000173655.1
ENSMUST00000100248.4
cleavage and polyadenylation specific factor 4-like
chr2_+_92382911 0.11 ENSMUST00000054316.2
ENSMUST00000111280.2
RIKEN cDNA 1700029I15 gene
chr16_+_36934976 0.11 ENSMUST00000023531.8
hematopoietic cell specific Lyn substrate 1
chr3_-_79842662 0.10 ENSMUST00000029568.1
transmembrane protein 144
chr3_+_101377074 0.10 ENSMUST00000043983.5
immunoglobulin superfamily, member 3
chr2_+_32363163 0.09 ENSMUST00000145635.1
CDKN1A interacting zinc finger protein 1
chr7_-_25005895 0.09 ENSMUST00000102858.3
ENSMUST00000080882.6
ATPase, Na+/K+ transporting, alpha 3 polypeptide
chr2_+_32363192 0.09 ENSMUST00000048964.7
ENSMUST00000113332.1
CDKN1A interacting zinc finger protein 1
chr11_-_58938851 0.09 ENSMUST00000094151.5
ring finger protein 187
chr2_+_32363004 0.08 ENSMUST00000132028.1
ENSMUST00000136079.1
CDKN1A interacting zinc finger protein 1
chr11_+_70459611 0.08 ENSMUST00000039093.3
zinc finger, MYND-type containing 15
chr6_-_38837224 0.06 ENSMUST00000160962.1
homeodomain interacting protein kinase 2
chr16_+_37916440 0.05 ENSMUST00000061274.7
G protein-coupled receptor 156
chr11_+_109485606 0.05 ENSMUST00000106697.1
arylsulfatase G
chr3_-_116712198 0.04 ENSMUST00000120120.1
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member 3
chr14_+_54476100 0.04 ENSMUST00000164766.1
ENSMUST00000164697.1
rad and gem related GTP binding protein 2
chr5_+_35814356 0.03 ENSMUST00000130233.1
actin-binding LIM protein 2
chr16_+_32419696 0.03 ENSMUST00000014220.8
ENSMUST00000080316.7
Tctex1 domain containing 2
chr18_+_77281958 0.02 ENSMUST00000096547.3
lipoxygenase homology domains 1
chr9_-_102626509 0.02 ENSMUST00000161645.1
ENSMUST00000162297.1
ENSMUST00000162655.1
centrosomal protein 63
chr5_+_108065742 0.02 ENSMUST00000081567.4
ENSMUST00000170319.1
ENSMUST00000112626.1
metal response element binding transcription factor 2
chr6_+_83237375 0.02 ENSMUST00000039212.7
ENSMUST00000113899.1
solute carrier family 4, sodium bicarbonate cotransporter, member 5
chr11_-_103344651 0.02 ENSMUST00000041385.7
Rho GTPase activating protein 27
chr11_-_113710017 0.02 ENSMUST00000018871.1
cleavage and polyadenylation specific factor 4-like
chr8_-_119501695 0.01 ENSMUST00000133821.1
ENSMUST00000036748.8
solute carrier family 38, member 8
chr9_+_102626278 0.01 ENSMUST00000038673.7
anaphase promoting complex subunit 13
chr19_-_38043559 0.01 ENSMUST00000041475.8
ENSMUST00000172095.2
myoferlin
chr13_+_30749226 0.01 ENSMUST00000021784.2
ENSMUST00000110307.1
interferon regulatory factor 4
chr15_-_100669496 0.00 ENSMUST00000182814.1
ENSMUST00000182068.1
bridging integrator 2
chrX_+_112311334 0.00 ENSMUST00000026599.3
ENSMUST00000113415.1
apolipoprotein O-like
chr10_+_87521920 0.00 ENSMUST00000142088.1
phenylalanine hydroxylase

Network of associatons between targets according to the STRING database.

First level regulatory network of Thrb

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0002318 myeloid progenitor cell differentiation(GO:0002318)
0.1 0.3 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.1 0.2 GO:1904882 telomerase catalytic core complex assembly(GO:1904868) regulation of telomerase catalytic core complex assembly(GO:1904882) positive regulation of telomerase catalytic core complex assembly(GO:1904884)
0.1 0.3 GO:0032298 positive regulation of DNA-dependent DNA replication initiation(GO:0032298)
0.1 0.2 GO:0005984 disaccharide metabolic process(GO:0005984)
0.0 0.1 GO:0015886 heme transport(GO:0015886)
0.0 0.2 GO:0042738 exogenous drug catabolic process(GO:0042738)
0.0 0.2 GO:2000767 positive regulation of cytoplasmic translation(GO:2000767)
0.0 0.3 GO:0034242 negative regulation of syncytium formation by plasma membrane fusion(GO:0034242)
0.0 0.4 GO:0010623 programmed cell death involved in cell development(GO:0010623)
0.0 0.3 GO:1903504 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.0 0.1 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0 0.5 GO:0001958 endochondral ossification(GO:0001958) replacement ossification(GO:0036075)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 GO:0005845 mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.0 0.7 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.7 GO:0097546 ciliary base(GO:0097546)
0.0 0.2 GO:0042788 polysomal ribosome(GO:0042788)
0.0 0.1 GO:0044326 dendritic spine neck(GO:0044326)
0.0 0.3 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.3 GO:0035098 ESC/E(Z) complex(GO:0035098)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.3 GO:0016151 nickel cation binding(GO:0016151)
0.0 0.2 GO:0032407 MutLalpha complex binding(GO:0032405) MutSalpha complex binding(GO:0032407)
0.0 0.7 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 0.2 GO:0008097 5S rRNA binding(GO:0008097)
0.0 0.2 GO:0008392 arachidonic acid epoxygenase activity(GO:0008392)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.0 0.7 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.2 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint