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2D miR_HR1_12

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Results for Nrf1

Z-value: 6.16

Motif logo

Transcription factors associated with Nrf1

Gene Symbol Gene ID Gene Info
ENSMUSG00000058440.8 nuclear respiratory factor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Nrf1mm10_v2_chr6_+_30047979_300480490.946.4e-06Click!

Activity profile of Nrf1 motif

Sorted Z-values of Nrf1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr11_-_40733373 22.25 ENSMUST00000020579.8
hyaluronan mediated motility receptor (RHAMM)
chr12_-_11265768 14.47 ENSMUST00000166117.1
Gen homolog 1, endonuclease (Drosophila)
chr16_-_90727329 11.70 ENSMUST00000099554.4
MIS18 kinetochore protein homolog A (S. pombe)
chr8_-_70234097 11.37 ENSMUST00000130319.1
armadillo repeat containing 6
chr8_+_122568001 11.32 ENSMUST00000006760.2
chromatin licensing and DNA replication factor 1
chr1_-_191575534 10.65 ENSMUST00000027933.5
denticleless homolog (Drosophila)
chr5_+_106964319 10.59 ENSMUST00000031221.5
ENSMUST00000117196.2
ENSMUST00000076467.6
cell division cycle 7 (S. cerevisiae)
chr11_-_11808923 10.50 ENSMUST00000109664.1
ENSMUST00000150714.1
ENSMUST00000047689.4
ENSMUST00000171938.1
ENSMUST00000171080.1
fidgetin-like 1
chr9_-_22389113 10.26 ENSMUST00000040912.7
anillin, actin binding protein
chr6_-_126939524 9.67 ENSMUST00000144954.1
ENSMUST00000112221.1
ENSMUST00000112220.1
RAD51 associated protein 1
chr3_-_54735001 8.96 ENSMUST00000153224.1
exosome component 8
chr6_+_66535390 8.72 ENSMUST00000116605.1
MAD2 mitotic arrest deficient-like 1
chr11_-_33163072 8.72 ENSMUST00000093201.6
ENSMUST00000101375.4
ENSMUST00000109354.3
ENSMUST00000075641.3
nucleophosmin 1
chr16_-_4003750 8.68 ENSMUST00000171658.1
ENSMUST00000171762.1
SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae)
chr5_-_77310049 8.61 ENSMUST00000047860.8
nitric oxide associated 1
chr2_-_172370506 8.53 ENSMUST00000109139.1
ENSMUST00000028997.7
ENSMUST00000109140.3
aurora kinase A
chr17_-_24251382 8.33 ENSMUST00000115390.3
cyclin F
chr2_+_157560078 8.27 ENSMUST00000153739.2
ENSMUST00000173595.1
ENSMUST00000109526.1
ENSMUST00000173839.1
ENSMUST00000173041.1
ENSMUST00000173793.1
ENSMUST00000172487.1
ENSMUST00000088484.5
neuronatin
chr6_+_66535418 8.20 ENSMUST00000101343.1
MAD2 mitotic arrest deficient-like 1
chr7_-_140787826 8.17 ENSMUST00000026553.4
synaptonemal complex central element protein 1
chr2_-_157007039 8.10 ENSMUST00000103129.2
ENSMUST00000103130.1
DSN1, MIND kinetochore complex component, homolog (S. cerevisiae)
chr18_-_74207771 6.93 ENSMUST00000040188.8
ENSMUST00000177604.1
spindle and kinetochore associated complex subunit 1
chr3_+_79629074 6.73 ENSMUST00000029388.8
RIKEN cDNA 4930579G24 gene
chr7_+_80294450 6.66 ENSMUST00000163812.2
ENSMUST00000047558.7
ENSMUST00000174199.1
ENSMUST00000173824.1
ENSMUST00000174172.1
protein regulator of cytokinesis 1
chr13_-_68582087 6.56 ENSMUST00000045827.4
5-methyltetrahydrofolate-homocysteine methyltransferase reductase
chr2_-_127133909 6.53 ENSMUST00000110387.3
non-SMC condensin I complex, subunit H
chr2_-_157007015 6.47 ENSMUST00000146413.1
DSN1, MIND kinetochore complex component, homolog (S. cerevisiae)
chr14_-_57826128 6.34 ENSMUST00000022536.2
spindle and kinetochore associated complex subunit 3
chrX_+_134308084 6.32 ENSMUST00000081064.5
ENSMUST00000101251.1
ENSMUST00000129782.1
centromere protein I
chr17_-_53689266 6.30 ENSMUST00000024736.7
shugoshin-like 1 (S. pombe)
chr7_+_18991245 6.15 ENSMUST00000130268.1
ENSMUST00000059331.8
ENSMUST00000131087.1
Myb-related transcription factor, partner of profilin
chr15_+_88751649 6.12 ENSMUST00000041297.8
zinc finger, BED domain containing 4
chr17_-_35897073 6.10 ENSMUST00000150056.1
ENSMUST00000156817.1
ENSMUST00000146451.1
ENSMUST00000148482.1
RIKEN cDNA 2310061I04 gene
chr12_-_110696248 6.04 ENSMUST00000124156.1
heat shock protein 90, alpha (cytosolic), class A member 1
chr13_-_55329723 6.04 ENSMUST00000021941.7
Max dimerization protein 3
chr7_+_44816088 5.97 ENSMUST00000057195.9
ENSMUST00000107891.1
nucleoporin 62
chr10_-_80855187 5.85 ENSMUST00000035775.8
LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr8_+_71406003 5.85 ENSMUST00000119976.1
ENSMUST00000120725.1
ankyrin repeat and LEM domain containing 1
chr8_-_70234401 5.84 ENSMUST00000019679.5
armadillo repeat containing 6
chr17_-_46202576 5.82 ENSMUST00000024749.7
polymerase (DNA directed), eta (RAD 30 related)
chr13_+_51645232 5.81 ENSMUST00000075853.5
CDC28 protein kinase regulatory subunit 2
chr17_+_26917091 5.72 ENSMUST00000078961.4
kinesin family member C5B
chr3_-_36571952 5.63 ENSMUST00000029270.3
cyclin A2
chr10_-_5805412 5.60 ENSMUST00000019907.7
F-box protein 5
chr17_-_71526819 5.54 ENSMUST00000024851.9
NDC80 homolog, kinetochore complex component (S. cerevisiae)
chr8_-_22185758 5.50 ENSMUST00000046916.7
cytoskeleton associated protein 2
chr10_+_128232065 5.50 ENSMUST00000055539.4
ENSMUST00000105244.1
ENSMUST00000105243.2
ENSMUST00000125289.1
ENSMUST00000105242.1
timeless circadian clock 1
chr11_+_40733936 5.49 ENSMUST00000127382.1
NudC domain containing 2
chr7_+_24507057 5.47 ENSMUST00000071361.6
zinc finger protein 428
chrX_+_159414572 5.36 ENSMUST00000112471.2
MAP7 domain containing 2
chr2_+_119047116 5.33 ENSMUST00000152380.1
ENSMUST00000099542.2
cancer susceptibility candidate 5
chr17_+_56304313 5.32 ENSMUST00000113035.1
ENSMUST00000113039.2
ENSMUST00000142387.1
ubiquitin-like, containing PHD and RING finger domains, 1
chr19_+_41911851 5.19 ENSMUST00000011896.6
phosphoglycerate mutase 1
chr17_-_35897371 5.18 ENSMUST00000148721.1
RIKEN cDNA 2310061I04 gene
chr12_-_110696289 5.16 ENSMUST00000021698.6
heat shock protein 90, alpha (cytosolic), class A member 1
chr17_-_35516780 5.15 ENSMUST00000160885.1
ENSMUST00000159009.1
ENSMUST00000161012.1
transcription factor 19
chr19_-_5964132 5.15 ENSMUST00000025752.7
ENSMUST00000165143.1
polymerase (DNA directed), alpha 2
chr10_+_80855275 5.07 ENSMUST00000035597.8
signal peptide peptidase like 2B
chr15_-_31601506 4.85 ENSMUST00000161266.1
chaperonin containing Tcp1, subunit 5 (epsilon)
chr11_-_102925086 4.77 ENSMUST00000021311.9
kinesin family member 18B
chr11_-_69921329 4.74 ENSMUST00000108613.3
ENSMUST00000043419.3
ENSMUST00000070996.4
eukaryotic translation initiation factor 5A
chr15_-_98881255 4.62 ENSMUST00000024518.9
Ras homolog enriched in brain like 1
chr2_+_119047129 4.58 ENSMUST00000153300.1
ENSMUST00000028799.5
cancer susceptibility candidate 5
chr7_+_24507122 4.54 ENSMUST00000177205.1
zinc finger protein 428
chr2_-_128943985 4.54 ENSMUST00000028866.8
zinc finger CCCH type containing 8
chr11_-_34833631 4.52 ENSMUST00000093191.2
spindle apparatus coiled-coil protein 1
chr7_+_24507006 4.52 ENSMUST00000176880.1
zinc finger protein 428
chr3_+_104638658 4.51 ENSMUST00000046212.1
solute carrier family 16 (monocarboxylic acid transporters), member 1
chr7_+_24507099 4.49 ENSMUST00000177228.1
zinc finger protein 428
chr9_+_55326913 4.46 ENSMUST00000085754.3
ENSMUST00000034862.4
expressed sequence AI118078
chr11_-_86544754 4.40 ENSMUST00000138810.1
ENSMUST00000058286.2
ENSMUST00000154617.1
ribosomal protein S6 kinase, polypeptide 1
chr12_+_78861693 4.40 ENSMUST00000071230.7
eukaryotic translation initiation factor 2, subunit 1 alpha
chrX_-_102157065 4.40 ENSMUST00000056904.2
excision repair cross-complementing rodent repair deficiency complementation group 6 like
chr9_-_106656081 4.37 ENSMUST00000023959.7
glutamate receptor, metabotropic 2
chr11_+_40733639 4.36 ENSMUST00000020578.4
NudC domain containing 2
chr3_-_108722281 4.36 ENSMUST00000029482.9
G-protein signalling modulator 2 (AGS3-like, C. elegans)
chr10_+_81070035 4.30 ENSMUST00000005057.6
thimet oligopeptidase 1
chr15_-_51991679 4.26 ENSMUST00000022927.9
RAD21 homolog (S. pombe)
chr2_-_153015331 4.23 ENSMUST00000028972.8
p53 and DNA damage regulated 1
chr3_+_40800013 4.21 ENSMUST00000026858.5
ENSMUST00000170825.1
polo-like kinase 4
chr9_-_106447584 4.20 ENSMUST00000171678.1
ENSMUST00000048685.6
ENSMUST00000171925.1
abhydrolase domain containing 14A
chr4_-_120570252 4.14 ENSMUST00000030381.7
cytidine 5'-triphosphate synthase
chr15_-_99651580 4.10 ENSMUST00000171908.1
ENSMUST00000171702.1
ENSMUST00000109581.2
ENSMUST00000169810.1
ENSMUST00000023756.5
Rac GTPase-activating protein 1
chr15_-_31601786 4.08 ENSMUST00000022842.8
chaperonin containing Tcp1, subunit 5 (epsilon)
chr12_-_110696332 4.07 ENSMUST00000094361.4
heat shock protein 90, alpha (cytosolic), class A member 1
chr17_+_34894515 4.06 ENSMUST00000052778.8
zinc finger and BTB domain containing 12
chr7_-_122132844 4.03 ENSMUST00000106469.1
ENSMUST00000063587.6
ENSMUST00000106468.1
ENSMUST00000130149.1
ENSMUST00000098068.3
partner and localizer of BRCA2
chr3_+_40800054 4.02 ENSMUST00000168287.1
polo-like kinase 4
chr10_-_63244135 4.00 ENSMUST00000054837.3
RIKEN cDNA 1700120B22 gene
chr16_+_18498768 4.00 ENSMUST00000167778.1
ENSMUST00000139625.1
ENSMUST00000149035.1
ENSMUST00000090086.4
ENSMUST00000115601.1
ENSMUST00000147739.1
ENSMUST00000146673.1
guanine nucleotide binding protein (G protein), beta polypeptide 1-like
predicted gene 16314
chr15_-_94543472 3.99 ENSMUST00000134061.1
ENSMUST00000049151.3
pseudouridylate synthase 7 homolog (S. cerevisiae)-like
chr3_-_69044697 3.99 ENSMUST00000136512.1
ENSMUST00000143454.1
ENSMUST00000107802.1
tripartite motif-containing 59
chr9_+_110132015 3.91 ENSMUST00000088716.5
ENSMUST00000111969.1
ENSMUST00000035057.7
ENSMUST00000111966.1
ENSMUST00000111968.1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1
chr18_+_80206775 3.91 ENSMUST00000145963.1
ENSMUST00000025464.7
ENSMUST00000125127.1
ENSMUST00000025463.7
thioredoxin-like 4A
predicted gene 16286
chr8_+_116921735 3.87 ENSMUST00000034205.4
centromere protein N
chr3_+_69004969 3.83 ENSMUST00000136502.1
ENSMUST00000107803.1
structural maintenance of chromosomes 4
chr2_+_32236579 3.81 ENSMUST00000036473.9
protein-O-mannosyltransferase 1
chr10_-_41809607 3.80 ENSMUST00000019951.9
centrosomal protein 57-like 1
chr15_+_103240405 3.79 ENSMUST00000036004.9
ENSMUST00000087351.7
heterogeneous nuclear ribonucleoprotein A1
chr9_-_21760275 3.77 ENSMUST00000098942.4
SPC24, NDC80 kinetochore complex component, homolog (S. cerevisiae)
chr15_-_76477269 3.75 ENSMUST00000023217.9
block of proliferation 1
chr6_-_148946146 3.74 ENSMUST00000132696.1
family with sequence similarity 60, member A
chr16_-_37654408 3.73 ENSMUST00000023514.3
NADH dehydrogenase (ubiquinone) 1 beta subcomplex 4
chr14_-_56778301 3.72 ENSMUST00000022507.5
ENSMUST00000163924.1
paraspeckle protein 1
chr3_+_69004711 3.71 ENSMUST00000042901.8
structural maintenance of chromosomes 4
chr9_-_20952838 3.70 ENSMUST00000004202.9
DNA methyltransferase (cytosine-5) 1
chr7_+_126862431 3.70 ENSMUST00000132808.1
HIRA interacting protein 3
chr13_-_24761861 3.69 ENSMUST00000006898.3
ENSMUST00000110382.2
geminin
chr10_+_20347788 3.69 ENSMUST00000169712.1
mitochondrial fission regulator 2
chrX_-_111463149 3.67 ENSMUST00000096348.3
ENSMUST00000113428.2
ribosomal protein S6 kinase polypeptide 6
chr4_+_55350043 3.66 ENSMUST00000030134.8
RAD23b homolog (S. cerevisiae)
chr13_-_69611421 3.65 ENSMUST00000091514.5
steroid 5 alpha-reductase 1
chr10_+_71347829 3.64 ENSMUST00000118381.1
ENSMUST00000121446.1
inositol polyphosphate multikinase
chr4_+_107367757 3.63 ENSMUST00000139560.1
NDC1 transmembrane nucleoporin
chr17_+_83350925 3.61 ENSMUST00000096766.4
ENSMUST00000112363.2
ENSMUST00000049503.8
echinoderm microtubule associated protein like 4
chr2_-_157135112 3.60 ENSMUST00000139263.1
SAM domain and HD domain, 1
chr8_-_126475062 3.60 ENSMUST00000170518.1
predicted gene, 17296
chr8_+_88137844 3.60 ENSMUST00000034079.7
ENSMUST00000121949.1
HEAT repeat containing 3
chrX_-_93632113 3.58 ENSMUST00000006856.2
polymerase (DNA directed), alpha 1
chr13_-_14613017 3.57 ENSMUST00000015816.3
mitochondrial ribosomal protein L32
chr12_+_11265867 3.56 ENSMUST00000020931.5
structural maintenance of chromosomes 6
chr11_+_115564434 3.55 ENSMUST00000021085.4
nucleoporin 85
chr9_+_106477269 3.48 ENSMUST00000047721.8
RRP9, small subunit (SSU) processome component, homolog (yeast)
chr11_+_101119938 3.43 ENSMUST00000043680.8
tubulin, gamma 1
chr4_-_132353605 3.36 ENSMUST00000155129.1
regulator of chromosome condensation 1
chrX_-_111463043 3.35 ENSMUST00000065976.5
ribosomal protein S6 kinase polypeptide 6
chr14_-_47276790 3.33 ENSMUST00000111792.1
ENSMUST00000111791.1
ENSMUST00000111790.1
WD repeat and HMG-box DNA binding protein 1
chr2_+_167062934 3.33 ENSMUST00000125674.1
RIKEN cDNA 1500012F01 gene
chr12_+_113156403 3.33 ENSMUST00000049271.8
RIKEN cDNA 4930427A07 gene
chr18_+_80206887 3.32 ENSMUST00000127234.1
predicted gene 16286
chr4_+_11558914 3.30 ENSMUST00000178703.1
ENSMUST00000095145.5
ENSMUST00000108306.2
ENSMUST00000070755.6
RAD54 homolog B (S. cerevisiae)
chr4_+_150236685 3.30 ENSMUST00000150175.1
enolase 1, alpha non-neuron
chr6_-_88627422 3.29 ENSMUST00000120933.2
ENSMUST00000169512.1
kelch repeat and BTB (POZ) domain containing 12
chr17_-_75551838 3.28 ENSMUST00000112507.3
family with sequence similarity 98, member A
chr7_+_24547150 3.27 ENSMUST00000063249.8
X-ray repair complementing defective repair in Chinese hamster cells 1
chrX_-_111463103 3.26 ENSMUST00000137712.2
ribosomal protein S6 kinase polypeptide 6
chr13_+_68582213 3.26 ENSMUST00000051784.8
FAST kinase domains 3
chr8_-_35495487 3.25 ENSMUST00000033927.6
exoribonuclease 1
chr5_+_129846980 3.24 ENSMUST00000171300.1
sulfatase modifying factor 2
chr17_+_66123520 3.24 ENSMUST00000163605.2
DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11
chr12_+_116405397 3.20 ENSMUST00000084828.3
non-SMC condensin II complex, subunit G2
chr14_+_70545251 3.19 ENSMUST00000047218.3
receptor accessory protein 4
chr11_+_86544982 3.19 ENSMUST00000108030.2
ENSMUST00000020821.3
ENSMUST00000069503.6
ENSMUST00000167178.2
tubulin, delta 1
chr4_-_155761042 3.18 ENSMUST00000030903.5
ATPase family, AAA domain containing 3A
chr9_-_53248106 3.18 ENSMUST00000065630.6
DEAD (Asp-Glu-Ala-Asp) box polypeptide 10
chr1_+_139422196 3.18 ENSMUST00000039867.7
zinc finger and BTB domain containing 41 homolog
chr17_-_28622479 3.17 ENSMUST00000130643.1
serine/arginine-rich protein specific kinase 1
chr7_+_45897429 3.17 ENSMUST00000140243.1
transmembrane protein 143
chr3_-_89418287 3.17 ENSMUST00000029679.3
CDC28 protein kinase 1b
chr13_-_74062262 3.16 ENSMUST00000036456.6
centrosomal protein 72
chr7_-_45896677 3.15 ENSMUST00000039049.7
synaptogyrin 4
chr14_+_101653967 3.15 ENSMUST00000002289.6
ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)
chr5_+_121397936 3.15 ENSMUST00000042163.8
N(alpha)-acetyltransferase 25, NatB auxiliary subunit
chrX_+_75096039 3.12 ENSMUST00000131155.1
ENSMUST00000132000.1
dyskeratosis congenita 1, dyskerin
chr1_+_55237177 3.11 ENSMUST00000061334.8
methionine-tRNA synthetase 2 (mitochondrial)
chr6_+_86365673 3.11 ENSMUST00000071492.7
family with sequence similarity 136, member A
chr19_-_47050823 3.10 ENSMUST00000026032.5
polycomb group ring finger 6
chr4_-_150909428 3.08 ENSMUST00000128075.1
ENSMUST00000105674.1
ENSMUST00000105673.1
Parkinson disease (autosomal recessive, early onset) 7
chr8_-_116921365 3.08 ENSMUST00000128304.1
COX assembly mitochondrial protein 2
chr11_-_69921190 3.06 ENSMUST00000108607.1
eukaryotic translation initiation factor 5A
chr13_+_24831661 3.06 ENSMUST00000038039.2
tyrosyl-DNA phosphodiesterase 2
chr10_+_71347736 3.06 ENSMUST00000079252.6
inositol polyphosphate multikinase
chr17_-_25727364 3.06 ENSMUST00000170070.1
ENSMUST00000048054.7
CTF18, chromosome transmission fidelity factor 18
chr10_-_80406811 3.06 ENSMUST00000020372.5
ubiquinol-cytochrome c reductase, complex III subunit XI
chr10_-_127288851 3.05 ENSMUST00000156208.1
ENSMUST00000026476.6
methyl-CpG binding domain protein 6
chr10_-_127288999 3.04 ENSMUST00000119078.1
methyl-CpG binding domain protein 6
chr4_+_123016590 3.00 ENSMUST00000102649.3
tRNA isopentenyltransferase 1
chr6_+_42264983 2.99 ENSMUST00000031895.6
caspase 2
chrX_-_48513518 2.98 ENSMUST00000114945.2
ENSMUST00000037349.7
apoptosis-inducing factor, mitochondrion-associated 1
chr10_-_117792663 2.97 ENSMUST00000167943.1
ENSMUST00000064848.5
nucleoporin 107
chr14_+_73142863 2.97 ENSMUST00000171767.1
ENSMUST00000163533.1
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
chr9_+_108936648 2.97 ENSMUST00000026743.8
ubiquinol-cytochrome c reductase core protein 1
chr7_+_140137559 2.96 ENSMUST00000036977.8
mitochondrial GTPase 1 homolog (S. cerevisiae)
chr2_-_146511899 2.93 ENSMUST00000131824.1
Ral GTPase activating protein, alpha subunit 2 (catalytic)
chr18_-_73815392 2.93 ENSMUST00000025439.3
malic enzyme 2, NAD(+)-dependent, mitochondrial
chr14_+_8080315 2.90 ENSMUST00000023924.3
ribonuclease P 14 subunit
chr4_-_86612009 2.88 ENSMUST00000125481.1
ENSMUST00000070607.7
HAUS augmin-like complex, subunit 6
chr17_-_31512253 2.88 ENSMUST00000166626.1
WD repeat domain 4
chr13_-_25020289 2.87 ENSMUST00000021772.2
MRS2 magnesium homeostasis factor homolog (S. cerevisiae)
chr11_-_69980468 2.87 ENSMUST00000143175.1
elongator acetyltransferase complex subunit 5
chr4_+_150236816 2.85 ENSMUST00000080926.6
enolase 1, alpha non-neuron
chr17_-_48432723 2.82 ENSMUST00000046549.3
apolipoprotein B mRNA editing enzyme, catalytic polypeptide 2
chr7_-_45896656 2.81 ENSMUST00000120299.1
synaptogyrin 4
chr10_+_63100156 2.81 ENSMUST00000044059.3
atonal homolog 7 (Drosophila)
chr13_+_76098734 2.81 ENSMUST00000091466.3
tetratricopeptide repeat domain 37
chr10_-_82623190 2.81 ENSMUST00000183363.1
ENSMUST00000079648.5
ENSMUST00000185168.1
RIKEN cDNA 1190007I07 gene
chr12_+_86678685 2.81 ENSMUST00000021681.3
vasohibin 1
chr11_+_77930800 2.80 ENSMUST00000093995.3
ENSMUST00000000646.7
seizure related gene 6
chr10_-_80039674 2.80 ENSMUST00000004786.9
polymerase (RNA) II (DNA directed) polypeptide E
chr1_-_86359455 2.78 ENSMUST00000027438.6
nucleolin
chr1_+_45795485 2.77 ENSMUST00000147308.1
WD repeat domain 75
chr16_-_45742888 2.76 ENSMUST00000128348.1
ENSMUST00000066983.6
abhydrolase domain containing 10
chr17_+_46202740 2.74 ENSMUST00000087031.5
exportin 5
chr16_+_94370786 2.74 ENSMUST00000147046.1
ENSMUST00000149885.1
ENSMUST00000127667.1
ENSMUST00000119131.1
ENSMUST00000145883.1
tetratricopeptide repeat domain 3
chr2_+_24949747 2.73 ENSMUST00000028350.3
zinc finger, MYND domain containing 19
chr11_+_98026695 2.72 ENSMUST00000092425.4
ribosomal protein L19
chr7_-_35647441 2.69 ENSMUST00000118501.1
programmed cell death 5
chr7_+_97371604 2.68 ENSMUST00000098300.4
asparagine-linked glycosylation 8 (alpha-1,3-glucosyltransferase)
chr12_-_108275409 2.67 ENSMUST00000136175.1
coiled-coil domain containing 85C
chr1_-_131138232 2.66 ENSMUST00000016670.7
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 3

Network of associatons between targets according to the STRING database.

First level regulatory network of Nrf1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
4.2 38.2 GO:0090267 positive regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090267)
4.2 12.5 GO:0000448 cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000448)
3.8 15.3 GO:0051316 attachment of spindle microtubules to kinetochore involved in meiotic chromosome segregation(GO:0051316)
3.8 11.3 GO:0071163 DNA replication preinitiation complex assembly(GO:0071163)
3.5 14.1 GO:0007056 spindle assembly involved in female meiosis(GO:0007056)
3.3 9.9 GO:1904170 regulation of bleb assembly(GO:1904170)
3.0 9.0 GO:0034473 U1 snRNA 3'-end processing(GO:0034473) U5 snRNA 3'-end processing(GO:0034476)
2.9 17.7 GO:0045583 regulation of cytotoxic T cell differentiation(GO:0045583) positive regulation of cytotoxic T cell differentiation(GO:0045585)
2.9 8.7 GO:1904975 response to bleomycin(GO:1904975) cellular response to bleomycin(GO:1904976)
2.9 8.7 GO:1904431 positive regulation of t-circle formation(GO:1904431)
2.6 10.6 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
2.2 6.5 GO:2000373 regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000371) positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000373)
2.1 6.3 GO:1903198 glycolate metabolic process(GO:0009441) enzyme active site formation via L-cysteine sulfinic acid(GO:0018323) primary alcohol biosynthetic process(GO:0034309) cellular response to glyoxal(GO:0036471) glycolate biosynthetic process(GO:0046295) negative regulation of TRAIL-activated apoptotic signaling pathway(GO:1903122) regulation of pyrroline-5-carboxylate reductase activity(GO:1903167) positive regulation of pyrroline-5-carboxylate reductase activity(GO:1903168) regulation of tyrosine 3-monooxygenase activity(GO:1903176) positive regulation of tyrosine 3-monooxygenase activity(GO:1903178) L-dopa metabolic process(GO:1903184) L-dopa biosynthetic process(GO:1903185) glyoxal metabolic process(GO:1903189) regulation of L-dopa biosynthetic process(GO:1903195) positive regulation of L-dopa biosynthetic process(GO:1903197) regulation of L-dopa decarboxylase activity(GO:1903198) positive regulation of L-dopa decarboxylase activity(GO:1903200) positive regulation of cellular amino acid biosynthetic process(GO:2000284)
2.0 14.2 GO:0046601 positive regulation of centriole replication(GO:0046601)
2.0 11.7 GO:0045905 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
1.9 11.7 GO:0061641 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
1.8 5.4 GO:0033566 gamma-tubulin complex localization(GO:0033566)
1.8 1.8 GO:0090172 microtubule cytoskeleton organization involved in homologous chromosome segregation(GO:0090172)
1.6 6.3 GO:0045950 negative regulation of mitotic recombination(GO:0045950)
1.5 4.6 GO:1903644 regulation of chaperone-mediated protein folding(GO:1903644)
1.5 3.0 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973)
1.4 7.2 GO:0017198 N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
1.4 5.8 GO:0006203 dGTP catabolic process(GO:0006203) dATP catabolic process(GO:0046061)
1.4 18.6 GO:0019985 translesion synthesis(GO:0019985)
1.4 4.2 GO:0016078 tRNA catabolic process(GO:0016078)
1.4 9.8 GO:0010032 meiotic chromosome condensation(GO:0010032)
1.4 8.4 GO:0090070 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
1.4 2.8 GO:2000232 regulation of rRNA processing(GO:2000232)
1.4 4.1 GO:0070843 misfolded protein transport(GO:0070843) polyubiquitinated protein transport(GO:0070844) polyubiquitinated misfolded protein transport(GO:0070845) Hsp90 deacetylation(GO:0070846)
1.3 5.3 GO:0090309 positive regulation of methylation-dependent chromatin silencing(GO:0090309)
1.3 1.3 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
1.3 5.0 GO:1904851 positive regulation of establishment of protein localization to telomere(GO:1904851)
1.2 2.4 GO:0043096 purine nucleobase salvage(GO:0043096)
1.2 3.6 GO:0006272 leading strand elongation(GO:0006272)
1.2 8.3 GO:0000320 re-entry into mitotic cell cycle(GO:0000320)
1.2 3.6 GO:0000722 telomere maintenance via recombination(GO:0000722)
1.2 4.7 GO:0045903 positive regulation of translational fidelity(GO:0045903)
1.2 13.0 GO:1904869 protein localization to nuclear body(GO:1903405) protein localization to Cajal body(GO:1904867) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871) protein localization to nucleoplasm(GO:1990173)
1.2 8.1 GO:1902031 regulation of NADP metabolic process(GO:1902031)
1.1 4.6 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
1.1 3.4 GO:1904098 regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
1.1 3.3 GO:1903632 positive regulation of aminoacyl-tRNA ligase activity(GO:1903632)
1.1 7.7 GO:0006290 pyrimidine dimer repair(GO:0006290)
1.1 4.4 GO:1904776 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
1.1 3.3 GO:0000715 nucleotide-excision repair, DNA damage recognition(GO:0000715)
1.1 3.3 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
1.1 3.2 GO:0007084 mitotic nuclear envelope reassembly(GO:0007084)
1.1 6.4 GO:1902659 regulation of glucose mediated signaling pathway(GO:1902659) positive regulation of glucose mediated signaling pathway(GO:1902661)
1.0 3.1 GO:0002842 positive regulation of T cell mediated immune response to tumor cell(GO:0002842)
1.0 5.1 GO:0051031 tRNA transport(GO:0051031)
1.0 3.0 GO:0000915 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
1.0 2.9 GO:0002276 basophil activation involved in immune response(GO:0002276)
1.0 2.9 GO:2000812 regulation of barbed-end actin filament capping(GO:2000812)
1.0 3.9 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
1.0 6.8 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.9 5.7 GO:0036123 histone H3-K9 dimethylation(GO:0036123)
0.9 6.6 GO:0000098 sulfur amino acid catabolic process(GO:0000098)
0.9 2.8 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
0.9 2.8 GO:0044337 canonical Wnt signaling pathway involved in positive regulation of apoptotic process(GO:0044337)
0.9 2.8 GO:0019389 glucuronoside metabolic process(GO:0019389)
0.9 2.7 GO:0099578 regulation of translation at synapse, modulating synaptic transmission(GO:0099547) regulation of translation at postsynapse, modulating synaptic transmission(GO:0099578) positive regulation of intracellular transport of viral material(GO:1901254)
0.9 4.4 GO:0031125 rRNA 3'-end processing(GO:0031125)
0.9 2.7 GO:0016132 brassinosteroid metabolic process(GO:0016131) brassinosteroid biosynthetic process(GO:0016132)
0.9 2.6 GO:1902990 mitotic telomere maintenance via semi-conservative replication(GO:1902990)
0.9 5.2 GO:0045876 positive regulation of sister chromatid cohesion(GO:0045876)
0.8 2.5 GO:0009051 pentose-phosphate shunt, oxidative branch(GO:0009051)
0.8 3.4 GO:0035609 C-terminal protein deglutamylation(GO:0035609)
0.8 3.3 GO:0070829 heterochromatin maintenance(GO:0070829)
0.8 2.5 GO:0071929 alpha-tubulin acetylation(GO:0071929)
0.8 2.4 GO:1904751 positive regulation of protein localization to nucleolus(GO:1904751)
0.8 8.1 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.8 10.3 GO:0036297 interstrand cross-link repair(GO:0036297)
0.8 4.6 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.8 3.8 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.8 0.8 GO:0032056 positive regulation of translation in response to stress(GO:0032056)
0.8 4.5 GO:0035879 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
0.7 0.7 GO:1904430 negative regulation of t-circle formation(GO:1904430)
0.7 8.7 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.7 3.6 GO:0010636 positive regulation of mitochondrial fusion(GO:0010636)
0.7 4.3 GO:0006545 glycine biosynthetic process(GO:0006545)
0.7 9.7 GO:2000381 negative regulation of mesoderm development(GO:2000381)
0.7 2.7 GO:1900368 regulation of RNA interference(GO:1900368)
0.7 2.7 GO:0099527 postsynapse to nucleus signaling pathway(GO:0099527)
0.7 2.7 GO:0032805 positive regulation of low-density lipoprotein particle receptor catabolic process(GO:0032805)
0.7 4.6 GO:0070458 detoxification of nitrogen compound(GO:0051410) cellular detoxification of nitrogen compound(GO:0070458)
0.6 5.2 GO:0033313 meiotic cell cycle checkpoint(GO:0033313)
0.6 4.4 GO:0048633 positive regulation of skeletal muscle tissue growth(GO:0048633)
0.6 1.9 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.6 25.2 GO:0010257 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.6 2.4 GO:0001835 blastocyst hatching(GO:0001835) hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.6 1.1 GO:0035983 response to trichostatin A(GO:0035983) cellular response to trichostatin A(GO:0035984)
0.6 1.1 GO:0071707 immunoglobulin heavy chain V-D-J recombination(GO:0071707)
0.6 4.4 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.6 1.7 GO:0006285 base-excision repair, AP site formation(GO:0006285)
0.5 3.8 GO:0060623 regulation of chromosome condensation(GO:0060623)
0.5 4.3 GO:0098762 meiotic prophase I(GO:0007128) prophase(GO:0051324) meiotic cell cycle phase(GO:0098762) meiosis I cell cycle phase(GO:0098764)
0.5 2.7 GO:0051105 regulation of DNA ligation(GO:0051105) positive regulation of DNA ligation(GO:0051106)
0.5 1.6 GO:0071169 establishment of protein localization to chromatin(GO:0071169)
0.5 5.7 GO:0090308 regulation of methylation-dependent chromatin silencing(GO:0090308)
0.5 4.1 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.5 5.7 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.5 1.5 GO:0007172 signal complex assembly(GO:0007172)
0.5 2.0 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.5 2.0 GO:0046125 pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.5 10.5 GO:0034508 centromere complex assembly(GO:0034508)
0.5 1.5 GO:0042780 tRNA 3'-end processing(GO:0042780) mitochondrial tRNA processing(GO:0090646)
0.5 2.0 GO:0075525 viral translational termination-reinitiation(GO:0075525)
0.5 2.0 GO:0032053 ciliary basal body organization(GO:0032053)
0.5 2.0 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.5 4.4 GO:0038203 TORC2 signaling(GO:0038203)
0.5 0.5 GO:0032253 dense core granule localization(GO:0032253) dense core granule transport(GO:1901950) regulation of dense core granule transport(GO:1904809) positive regulation of dense core granule transport(GO:1904811)
0.5 2.4 GO:0014886 transition between slow and fast fiber(GO:0014886)
0.5 2.4 GO:0006741 NADP biosynthetic process(GO:0006741)
0.5 3.9 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.5 1.9 GO:0042822 pyridoxal phosphate metabolic process(GO:0042822)
0.5 1.4 GO:0009173 UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.5 0.5 GO:0043634 polyadenylation-dependent RNA catabolic process(GO:0043633) polyadenylation-dependent ncRNA catabolic process(GO:0043634)
0.5 4.7 GO:0034501 protein localization to kinetochore(GO:0034501)
0.5 4.2 GO:0000479 endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000479)
0.5 1.9 GO:0060331 negative regulation of response to interferon-gamma(GO:0060331) negative regulation of interferon-gamma-mediated signaling pathway(GO:0060336)
0.5 6.5 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.5 1.4 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.5 1.4 GO:0048298 regulation of isotype switching to IgA isotypes(GO:0048296) positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.5 1.8 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
0.5 1.8 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.4 2.2 GO:0032957 inositol trisphosphate metabolic process(GO:0032957)
0.4 4.0 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.4 3.5 GO:1905216 positive regulation of RNA binding(GO:1905216)
0.4 1.3 GO:0006435 threonyl-tRNA aminoacylation(GO:0006435)
0.4 1.8 GO:0045040 protein import into mitochondrial outer membrane(GO:0045040)
0.4 3.9 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.4 0.9 GO:0018171 peptidyl-cysteine oxidation(GO:0018171)
0.4 2.1 GO:0070535 histone H2A K63-linked ubiquitination(GO:0070535)
0.4 1.7 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.4 1.3 GO:2000793 left ventricular cardiac muscle tissue morphogenesis(GO:0003220) positive regulation of follicle-stimulating hormone secretion(GO:0046881) cell proliferation involved in heart valve development(GO:2000793)
0.4 2.9 GO:0036265 RNA (guanine-N7)-methylation(GO:0036265)
0.4 1.6 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.4 1.6 GO:0060025 regulation of synaptic activity(GO:0060025)
0.4 1.2 GO:0044313 protein K6-linked deubiquitination(GO:0044313) protein K27-linked deubiquitination(GO:1990167)
0.4 2.8 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.4 1.2 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.4 4.4 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.4 2.7 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.4 2.3 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
0.4 3.1 GO:0016576 histone dephosphorylation(GO:0016576)
0.4 3.8 GO:1902036 regulation of hematopoietic stem cell differentiation(GO:1902036)
0.4 2.3 GO:0000469 cleavage involved in rRNA processing(GO:0000469)
0.4 3.4 GO:0036093 germ cell proliferation(GO:0036093)
0.4 1.5 GO:0002949 tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.4 9.1 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.4 0.8 GO:0009446 putrescine biosynthetic process(GO:0009446)
0.4 3.4 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.4 1.1 GO:0046168 glycerol-3-phosphate catabolic process(GO:0046168)
0.4 1.1 GO:2000584 regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583) negative regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000584)
0.4 1.5 GO:0006529 asparagine biosynthetic process(GO:0006529)
0.4 1.1 GO:0006528 asparagine metabolic process(GO:0006528)
0.4 1.1 GO:1902949 positive regulation of tau-protein kinase activity(GO:1902949)
0.4 0.7 GO:0060844 Notch signaling pathway involved in heart induction(GO:0003137) regulation of Notch signaling pathway involved in heart induction(GO:0035480) positive regulation of Notch signaling pathway involved in heart induction(GO:0035481) arterial endothelial cell fate commitment(GO:0060844) blood vessel endothelial cell fate commitment(GO:0060846) endothelial cell fate specification(GO:0060847) Notch signaling pathway involved in arterial endothelial cell fate commitment(GO:0060853) regulation of heart induction(GO:0090381) blood vessel endothelial cell fate specification(GO:0097101) positive regulation of heart induction(GO:1901321)
0.4 2.9 GO:0006271 DNA strand elongation involved in DNA replication(GO:0006271)
0.4 0.4 GO:0048239 negative regulation of DNA recombination at telomere(GO:0048239) regulation of DNA recombination at telomere(GO:0072695)
0.4 2.5 GO:2000767 positive regulation of cytoplasmic translation(GO:2000767)
0.4 1.1 GO:0016598 protein arginylation(GO:0016598)
0.4 1.4 GO:0071930 negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930)
0.4 2.8 GO:0016554 cytidine to uridine editing(GO:0016554)
0.3 0.7 GO:1900157 regulation of bone mineralization involved in bone maturation(GO:1900157)
0.3 8.0 GO:0006270 DNA replication initiation(GO:0006270)
0.3 2.7 GO:0009452 7-methylguanosine RNA capping(GO:0009452) RNA capping(GO:0036260)
0.3 1.3 GO:0044376 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.3 1.0 GO:0032377 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.3 1.0 GO:0000460 maturation of 5.8S rRNA(GO:0000460)
0.3 6.0 GO:0001522 pseudouridine synthesis(GO:0001522)
0.3 2.6 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.3 1.7 GO:2000210 positive regulation of anoikis(GO:2000210)
0.3 7.9 GO:0043457 regulation of cellular respiration(GO:0043457)
0.3 4.9 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.3 4.6 GO:0070673 response to interleukin-18(GO:0070673)
0.3 1.3 GO:0051315 attachment of mitotic spindle microtubules to kinetochore(GO:0051315)
0.3 4.1 GO:0006241 CTP biosynthetic process(GO:0006241) CTP metabolic process(GO:0046036)
0.3 1.0 GO:0019230 proprioception(GO:0019230)
0.3 1.6 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.3 8.1 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.3 0.3 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.3 0.9 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
0.3 1.5 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.3 0.6 GO:0021508 floor plate formation(GO:0021508)
0.3 1.2 GO:0010635 regulation of mitochondrial fusion(GO:0010635) negative regulation of mitochondrial fusion(GO:0010637)
0.3 8.2 GO:0010569 regulation of double-strand break repair via homologous recombination(GO:0010569)
0.3 1.8 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.3 3.0 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977)
0.3 3.9 GO:0006337 nucleosome disassembly(GO:0006337)
0.3 2.1 GO:0032790 ribosome disassembly(GO:0032790)
0.3 0.9 GO:0051935 amino acid neurotransmitter reuptake(GO:0051933) glutamate reuptake(GO:0051935)
0.3 3.0 GO:0008298 intracellular mRNA localization(GO:0008298)
0.3 1.2 GO:0071267 L-methionine biosynthetic process from methylthioadenosine(GO:0019509) amino acid salvage(GO:0043102) L-methionine salvage(GO:0071267)
0.3 1.2 GO:0043504 mitochondrial DNA repair(GO:0043504)
0.3 0.9 GO:0060830 ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830)
0.3 5.5 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.3 1.7 GO:0000056 ribosomal small subunit export from nucleus(GO:0000056)
0.3 0.6 GO:0051329 interphase(GO:0051325) mitotic interphase(GO:0051329)
0.3 3.1 GO:0031571 mitotic G1 DNA damage checkpoint(GO:0031571)
0.3 1.7 GO:0060178 regulation of exocyst localization(GO:0060178)
0.3 1.4 GO:0006450 regulation of translational fidelity(GO:0006450)
0.3 0.8 GO:1990859 cellular response to endothelin(GO:1990859)
0.3 3.6 GO:0006702 androgen biosynthetic process(GO:0006702)
0.3 3.3 GO:0016926 protein desumoylation(GO:0016926)
0.3 4.4 GO:0006490 oligosaccharide-lipid intermediate biosynthetic process(GO:0006490)
0.3 1.4 GO:0042117 monocyte activation(GO:0042117)
0.3 0.6 GO:0061738 late endosomal microautophagy(GO:0061738)
0.3 3.5 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.3 1.1 GO:0033750 ribosomal subunit export from nucleus(GO:0000054) ribosome localization(GO:0033750) establishment of ribosome localization(GO:0033753)
0.3 1.9 GO:0006362 transcription elongation from RNA polymerase I promoter(GO:0006362)
0.3 1.3 GO:0070127 tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.3 0.5 GO:0008616 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.3 0.8 GO:1904779 regulation of protein localization to centrosome(GO:1904779)
0.3 3.5 GO:0031581 hemidesmosome assembly(GO:0031581)
0.3 3.4 GO:0000212 meiotic spindle organization(GO:0000212)
0.3 2.8 GO:0009438 methylglyoxal metabolic process(GO:0009438)
0.3 2.0 GO:0030300 regulation of intestinal cholesterol absorption(GO:0030300)
0.3 1.5 GO:0071484 cellular response to light intensity(GO:0071484) cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473)
0.2 12.2 GO:0000245 spliceosomal complex assembly(GO:0000245)
0.2 0.7 GO:0051661 maintenance of centrosome location(GO:0051661)
0.2 14.7 GO:0007019 microtubule depolymerization(GO:0007019)
0.2 1.0 GO:0070542 response to fatty acid(GO:0070542)
0.2 0.7 GO:0061354 hypophysis morphogenesis(GO:0048850) cervix development(GO:0060067) lateral sprouting involved in mammary gland duct morphogenesis(GO:0060599) planar cell polarity pathway involved in outflow tract morphogenesis(GO:0061347) planar cell polarity pathway involved in ventricular septum morphogenesis(GO:0061348) planar cell polarity pathway involved in cardiac right atrium morphogenesis(GO:0061349) planar cell polarity pathway involved in cardiac muscle tissue morphogenesis(GO:0061350) planar cell polarity pathway involved in pericardium morphogenesis(GO:0061354) regulation of cell proliferation in midbrain(GO:1904933)
0.2 1.7 GO:0010993 regulation of ubiquitin homeostasis(GO:0010993) free ubiquitin chain polymerization(GO:0010994)
0.2 0.2 GO:0060399 positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.2 0.7 GO:0031296 B cell costimulation(GO:0031296)
0.2 1.6 GO:0000972 transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000972)
0.2 0.9 GO:1903061 positive regulation of protein lipidation(GO:1903061)
0.2 2.8 GO:0021554 optic nerve development(GO:0021554)
0.2 0.7 GO:0008612 peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.2 1.4 GO:0060075 regulation of resting membrane potential(GO:0060075)
0.2 2.5 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.2 6.8 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.2 1.1 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.2 0.7 GO:0050847 progesterone receptor signaling pathway(GO:0050847)
0.2 10.0 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.2 11.7 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.2 0.9 GO:1902172 keratinocyte apoptotic process(GO:0097283) regulation of keratinocyte apoptotic process(GO:1902172)
0.2 1.3 GO:0090261 positive regulation of inclusion body assembly(GO:0090261)
0.2 2.4 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.2 0.7 GO:0072697 protein localization to cell cortex(GO:0072697)
0.2 0.4 GO:0090365 regulation of mRNA modification(GO:0090365)
0.2 0.7 GO:1901300 positive regulation of hydrogen peroxide-mediated programmed cell death(GO:1901300)
0.2 1.1 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
0.2 1.7 GO:0006265 DNA topological change(GO:0006265)
0.2 1.1 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.2 1.1 GO:0006538 glutamate catabolic process(GO:0006538)
0.2 1.3 GO:0019720 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720)
0.2 0.6 GO:0016256 N-glycan processing to lysosome(GO:0016256)
0.2 1.3 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.2 1.7 GO:1990035 calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.2 4.1 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.2 0.8 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.2 6.4 GO:0016572 histone phosphorylation(GO:0016572)
0.2 1.4 GO:0035356 cellular triglyceride homeostasis(GO:0035356)
0.2 1.4 GO:1903350 response to dopamine(GO:1903350) cellular response to dopamine(GO:1903351)
0.2 1.2 GO:0006102 isocitrate metabolic process(GO:0006102)
0.2 1.2 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.2 3.8 GO:0032516 positive regulation of phosphoprotein phosphatase activity(GO:0032516)
0.2 1.2 GO:0007258 JUN phosphorylation(GO:0007258)
0.2 1.6 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.2 6.7 GO:0010259 multicellular organism aging(GO:0010259)
0.2 1.6 GO:0071816 tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.2 1.4 GO:0046349 amino sugar biosynthetic process(GO:0046349)
0.2 2.9 GO:0051131 chaperone-mediated protein complex assembly(GO:0051131)
0.2 1.2 GO:1990928 response to amino acid starvation(GO:1990928)
0.2 0.8 GO:0008295 spermidine biosynthetic process(GO:0008295)
0.2 0.9 GO:1990034 calcium ion export from cell(GO:1990034)
0.2 3.0 GO:0051823 regulation of synapse structural plasticity(GO:0051823)
0.2 0.6 GO:0061537 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.2 2.1 GO:0000002 mitochondrial genome maintenance(GO:0000002)
0.2 1.5 GO:0000012 single strand break repair(GO:0000012)
0.2 1.9 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.2 1.8 GO:0051292 nuclear pore complex assembly(GO:0051292)
0.2 1.5 GO:0071168 protein localization to chromatin(GO:0071168)
0.2 0.7 GO:0072321 chaperone-mediated protein transport(GO:0072321)
0.2 3.3 GO:0071173 mitotic spindle assembly checkpoint(GO:0007094) spindle assembly checkpoint(GO:0071173)
0.2 0.4 GO:0090151 establishment of protein localization to mitochondrial membrane(GO:0090151)
0.2 0.9 GO:0006348 chromatin silencing at telomere(GO:0006348)
0.2 0.5 GO:0010701 positive regulation of norepinephrine secretion(GO:0010701)
0.2 1.1 GO:0001514 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.2 0.7 GO:0035247 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919) histone arginine methylation(GO:0034969) peptidyl-arginine N-methylation(GO:0035246) peptidyl-arginine omega-N-methylation(GO:0035247)
0.2 1.7 GO:0045719 negative regulation of glycogen biosynthetic process(GO:0045719)
0.2 1.0 GO:0060339 negative regulation of type I interferon-mediated signaling pathway(GO:0060339)
0.2 1.4 GO:0051490 negative regulation of filopodium assembly(GO:0051490)
0.2 8.2 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.2 0.7 GO:0021776 smoothened signaling pathway involved in ventral spinal cord interneuron specification(GO:0021775) smoothened signaling pathway involved in spinal cord motor neuron cell fate specification(GO:0021776)
0.2 0.8 GO:0045541 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.2 0.5 GO:0009113 purine nucleobase biosynthetic process(GO:0009113)
0.2 1.0 GO:0042997 negative regulation of Golgi to plasma membrane protein transport(GO:0042997) negative regulation of establishment of protein localization to plasma membrane(GO:0090005)
0.2 2.2 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.2 2.0 GO:0060213 regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060211) positive regulation of nuclear-transcribed mRNA poly(A) tail shortening(GO:0060213)
0.2 0.5 GO:0035511 oxidative DNA demethylation(GO:0035511)
0.2 0.6 GO:0051697 protein delipidation(GO:0051697)
0.2 0.5 GO:0001302 replicative cell aging(GO:0001302)
0.2 0.6 GO:0097298 regulation of nucleus size(GO:0097298)
0.2 0.8 GO:0033140 negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140)
0.2 1.0 GO:0031441 negative regulation of mRNA 3'-end processing(GO:0031441) negative regulation of mRNA polyadenylation(GO:1900364)
0.2 0.9 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.2 0.6 GO:0051643 endoplasmic reticulum localization(GO:0051643)
0.2 0.6 GO:2001245 negative regulation of phospholipid biosynthetic process(GO:0071072) regulation of phosphatidylcholine biosynthetic process(GO:2001245)
0.2 0.5 GO:0097402 neuroblast migration(GO:0097402)
0.2 0.9 GO:0051418 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.2 0.5 GO:0010730 negative regulation of hydrogen peroxide biosynthetic process(GO:0010730)
0.2 3.2 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.2 0.8 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
0.2 0.3 GO:0036090 cleavage furrow ingression(GO:0036090)
0.2 0.5 GO:0098974 postsynaptic actin cytoskeleton organization(GO:0098974)
0.2 0.9 GO:0006020 inositol metabolic process(GO:0006020)
0.2 0.6 GO:0070537 histone H2A K63-linked deubiquitination(GO:0070537)
0.2 0.5 GO:0035627 ER to Golgi ceramide transport(GO:0035621) ceramide transport(GO:0035627)
0.2 0.6 GO:0051122 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.1 0.6 GO:0044597 polyketide metabolic process(GO:0030638) aminoglycoside antibiotic metabolic process(GO:0030647) daunorubicin metabolic process(GO:0044597) doxorubicin metabolic process(GO:0044598)
0.1 4.3 GO:0032958 inositol phosphate biosynthetic process(GO:0032958)
0.1 3.0 GO:0044065 regulation of respiratory system process(GO:0044065)
0.1 4.6 GO:0038202 TORC1 signaling(GO:0038202)
0.1 1.0 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.1 1.2 GO:0033262 regulation of nuclear cell cycle DNA replication(GO:0033262)
0.1 1.0 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.1 0.4 GO:2000978 negative regulation of forebrain neuron differentiation(GO:2000978)
0.1 2.3 GO:0051900 regulation of mitochondrial depolarization(GO:0051900)
0.1 1.9 GO:0043248 proteasome assembly(GO:0043248)
0.1 7.6 GO:0051703 social behavior(GO:0035176) intraspecies interaction between organisms(GO:0051703)
0.1 3.9 GO:0032786 positive regulation of DNA-templated transcription, elongation(GO:0032786)
0.1 1.1 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.1 2.4 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.1 0.9 GO:1904668 positive regulation of ubiquitin protein ligase activity(GO:1904668)
0.1 4.5 GO:0006414 translational elongation(GO:0006414)
0.1 0.4 GO:0043097 pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
0.1 1.7 GO:1903423 positive regulation of synaptic vesicle recycling(GO:1903423)
0.1 0.6 GO:0016240 autophagosome docking(GO:0016240)
0.1 0.7 GO:0051561 positive regulation of mitochondrial calcium ion concentration(GO:0051561)
0.1 1.4 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.1 0.4 GO:1903294 regulation of glutamate secretion, neurotransmission(GO:1903294) positive regulation of glutamate secretion, neurotransmission(GO:1903296)
0.1 0.8 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.1 1.2 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.1 1.2 GO:0018344 protein geranylgeranylation(GO:0018344)
0.1 4.2 GO:1990542 mitochondrial transmembrane transport(GO:1990542)
0.1 1.1 GO:0021785 branchiomotor neuron axon guidance(GO:0021785)
0.1 0.9 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.1 0.7 GO:0070813 hydrogen sulfide metabolic process(GO:0070813)
0.1 3.4 GO:0051290 protein heterotetramerization(GO:0051290)
0.1 1.5 GO:0051310 metaphase plate congression(GO:0051310)
0.1 0.5 GO:0051204 protein insertion into mitochondrial membrane(GO:0051204)
0.1 2.8 GO:0090036 regulation of protein kinase C signaling(GO:0090036)
0.1 0.4 GO:0042706 eye photoreceptor cell fate commitment(GO:0042706) photoreceptor cell fate commitment(GO:0046552) camera-type eye photoreceptor cell fate commitment(GO:0060220)
0.1 0.5 GO:0002183 cytoplasmic translational initiation(GO:0002183)
0.1 0.5 GO:0010286 heat acclimation(GO:0010286)
0.1 0.4 GO:0002036 regulation of L-glutamate transport(GO:0002036)
0.1 21.4 GO:0002244 hematopoietic progenitor cell differentiation(GO:0002244)
0.1 0.9 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.1 1.3 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.1 0.3 GO:2000825 positive regulation of androgen receptor activity(GO:2000825)
0.1 0.9 GO:0001880 Mullerian duct regression(GO:0001880)
0.1 6.8 GO:0000380 alternative mRNA splicing, via spliceosome(GO:0000380)
0.1 0.5 GO:0070213 protein auto-ADP-ribosylation(GO:0070213)
0.1 0.6 GO:0072368 regulation of lipid transport by negative regulation of transcription from RNA polymerase II promoter(GO:0072368)
0.1 1.2 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.1 15.4 GO:0000377 RNA splicing, via transesterification reactions(GO:0000375) RNA splicing, via transesterification reactions with bulged adenosine as nucleophile(GO:0000377) mRNA splicing, via spliceosome(GO:0000398)
0.1 0.5 GO:1903966 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.1 11.2 GO:0006352 DNA-templated transcription, initiation(GO:0006352)
0.1 3.0 GO:0070918 dsRNA fragmentation(GO:0031050) production of miRNAs involved in gene silencing by miRNA(GO:0035196) production of small RNA involved in gene silencing by RNA(GO:0070918)
0.1 1.9 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.1 0.9 GO:0060216 definitive hemopoiesis(GO:0060216)
0.1 0.6 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.1 1.3 GO:0006353 DNA-templated transcription, termination(GO:0006353)
0.1 1.1 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.1 0.9 GO:0016180 snRNA processing(GO:0016180)
0.1 1.5 GO:0046548 retinal rod cell development(GO:0046548)
0.1 0.4 GO:0021812 neuronal-glial interaction involved in cerebral cortex radial glia guided migration(GO:0021812)
0.1 0.3 GO:0098928 presynaptic signal transduction(GO:0098928) presynapse to nucleus signaling pathway(GO:0099526)
0.1 0.8 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.1 5.6 GO:0031110 regulation of microtubule polymerization or depolymerization(GO:0031110)
0.1 4.5 GO:0050850 positive regulation of calcium-mediated signaling(GO:0050850)
0.1 0.9 GO:0061635 regulation of protein complex stability(GO:0061635)
0.1 0.3 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.1 1.0 GO:1901096 regulation of autophagosome maturation(GO:1901096)
0.1 0.6 GO:0015015 heparan sulfate proteoglycan biosynthetic process, enzymatic modification(GO:0015015)
0.1 2.6 GO:0014047 glutamate secretion(GO:0014047)
0.1 1.8 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.1 3.6 GO:0006400 tRNA modification(GO:0006400)
0.1 3.1 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.1 8.3 GO:0042254 ribosome biogenesis(GO:0042254)
0.1 1.4 GO:0035646 endosome to melanosome transport(GO:0035646) endosome to pigment granule transport(GO:0043485) pigment granule maturation(GO:0048757)
0.1 0.9 GO:0006346 methylation-dependent chromatin silencing(GO:0006346)
0.1 1.8 GO:0098902 regulation of membrane depolarization during action potential(GO:0098902)
0.1 0.7 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.1 2.9 GO:0000070 mitotic sister chromatid segregation(GO:0000070)
0.1 1.4 GO:0070193 synaptonemal complex organization(GO:0070193)
0.1 0.2 GO:0043974 histone H3-K27 acetylation(GO:0043974) regulation of histone H3-K27 acetylation(GO:1901674)
0.1 1.8 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.1 0.9 GO:0042136 neurotransmitter biosynthetic process(GO:0042136)
0.1 0.7 GO:0016266 O-glycan processing(GO:0016266)
0.1 0.5 GO:0051571 positive regulation of histone H3-K4 methylation(GO:0051571)
0.1 1.8 GO:0030262 cellular component disassembly involved in execution phase of apoptosis(GO:0006921) apoptotic nuclear changes(GO:0030262)
0.1 0.7 GO:1902514 regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1902514)
0.1 1.9 GO:0007099 centriole replication(GO:0007099)
0.1 3.1 GO:0042755 eating behavior(GO:0042755)
0.1 0.3 GO:0042271 susceptibility to natural killer cell mediated cytotoxicity(GO:0042271)
0.1 0.3 GO:0061156 pulmonary artery morphogenesis(GO:0061156)
0.1 0.6 GO:0010566 regulation of ketone biosynthetic process(GO:0010566)
0.1 1.2 GO:0061029 eyelid development in camera-type eye(GO:0061029)
0.1 0.4 GO:0070178 D-serine metabolic process(GO:0070178)
0.1 9.3 GO:0045333 cellular respiration(GO:0045333)
0.1 1.0 GO:0009303 rRNA transcription(GO:0009303)
0.1 0.7 GO:0042989 sequestering of actin monomers(GO:0042989)
0.1 1.3 GO:0015809 arginine transport(GO:0015809)
0.1 0.6 GO:0060693 regulation of branching involved in salivary gland morphogenesis(GO:0060693)
0.1 0.8 GO:1905206 positive regulation of hydrogen peroxide-induced cell death(GO:1905206)
0.1 0.8 GO:0042756 drinking behavior(GO:0042756)
0.1 1.1 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.1 0.7 GO:1901503 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.1 0.9 GO:0051444 negative regulation of ubiquitin-protein transferase activity(GO:0051444)
0.1 0.5 GO:0010996 response to auditory stimulus(GO:0010996)
0.1 0.5 GO:2000819 regulation of nucleotide-excision repair(GO:2000819)
0.1 2.4 GO:0014003 oligodendrocyte development(GO:0014003)
0.1 0.4 GO:0051013 microtubule severing(GO:0051013)
0.1 0.6 GO:2000288 positive regulation of myoblast proliferation(GO:2000288)
0.1 0.9 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.1 1.8 GO:2000191 regulation of fatty acid transport(GO:2000191)
0.1 1.0 GO:0040001 establishment of mitotic spindle localization(GO:0040001)
0.1 0.2 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.1 0.2 GO:0042275 error-free postreplication DNA repair(GO:0042275)
0.1 0.9 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.1 1.3 GO:0060259 regulation of feeding behavior(GO:0060259)
0.1 0.4 GO:0090394 negative regulation of excitatory postsynaptic potential(GO:0090394)
0.1 0.3 GO:0032486 Rap protein signal transduction(GO:0032486)
0.1 0.7 GO:0055003 cardiac myofibril assembly(GO:0055003)
0.1 0.4 GO:0007182 common-partner SMAD protein phosphorylation(GO:0007182)
0.1 2.0 GO:0044342 type B pancreatic cell proliferation(GO:0044342)
0.1 0.3 GO:0010529 regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529)
0.1 1.3 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.1 0.1 GO:1901407 regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901407)
0.1 3.4 GO:0051225 spindle assembly(GO:0051225)
0.1 1.3 GO:0001516 prostaglandin biosynthetic process(GO:0001516) prostanoid biosynthetic process(GO:0046457)
0.1 0.1 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.1 2.4 GO:0051865 protein autoubiquitination(GO:0051865)
0.1 0.7 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.1 1.4 GO:0045116 protein neddylation(GO:0045116)
0.1 1.3 GO:0008033 tRNA processing(GO:0008033)
0.1 0.6 GO:0051205 protein insertion into membrane(GO:0051205)
0.1 0.4 GO:0034141 positive regulation of toll-like receptor 3 signaling pathway(GO:0034141)
0.1 0.2 GO:1900034 regulation of cellular response to heat(GO:1900034)
0.1 2.7 GO:0006801 superoxide metabolic process(GO:0006801)
0.1 0.8 GO:0031017 exocrine pancreas development(GO:0031017)
0.1 1.0 GO:0048745 smooth muscle tissue development(GO:0048745)
0.1 0.3 GO:0051026 chiasma assembly(GO:0051026)
0.1 0.9 GO:0070544 histone H3-K36 demethylation(GO:0070544)
0.1 2.4 GO:0048286 lung alveolus development(GO:0048286)
0.1 0.3 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.1 0.5 GO:0033147 negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.1 0.8 GO:0071420 cellular response to histamine(GO:0071420)
0.1 1.9 GO:0000724 double-strand break repair via homologous recombination(GO:0000724) recombinational repair(GO:0000725)
0.1 0.2 GO:1902047 polyamine transmembrane transport(GO:1902047) regulation of polyamine transmembrane transport(GO:1902267)
0.1 1.8 GO:0006611 protein export from nucleus(GO:0006611)
0.1 0.2 GO:1903147 negative regulation of mitophagy(GO:1903147)
0.1 2.3 GO:0048246 macrophage chemotaxis(GO:0048246)
0.1 1.6 GO:1902108 regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902108)
0.1 0.2 GO:1902528 regulation of protein linear polyubiquitination(GO:1902528) positive regulation of protein linear polyubiquitination(GO:1902530)
0.1 0.2 GO:0060671 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.1 1.0 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.1 1.7 GO:2001022 positive regulation of response to DNA damage stimulus(GO:2001022)
0.1 0.7 GO:0015781 pyrimidine nucleotide-sugar transport(GO:0015781)
0.1 0.6 GO:0019359 nicotinamide nucleotide biosynthetic process(GO:0019359)
0.1 0.2 GO:0015886 heme transport(GO:0015886)
0.1 0.8 GO:0016558 protein import into peroxisome matrix(GO:0016558)
0.1 0.5 GO:0070986 left/right axis specification(GO:0070986)
0.0 0.7 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 0.0 GO:2000049 positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
0.0 5.6 GO:0071229 cellular response to acid chemical(GO:0071229)
0.0 2.1 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 0.4 GO:0071157 negative regulation of cell cycle arrest(GO:0071157)
0.0 0.2 GO:0070072 vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 1.0 GO:1900449 regulation of glutamate receptor signaling pathway(GO:1900449)
0.0 1.2 GO:0034308 primary alcohol metabolic process(GO:0034308)
0.0 0.4 GO:0046541 saliva secretion(GO:0046541)
0.0 1.6 GO:0001662 behavioral fear response(GO:0001662)
0.0 2.7 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.0 0.5 GO:0008535 respiratory chain complex IV assembly(GO:0008535)
0.0 0.4 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.3 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.0 0.2 GO:0008300 isoprenoid catabolic process(GO:0008300)
0.0 2.5 GO:0006334 nucleosome assembly(GO:0006334)
0.0 0.3 GO:0071880 adenylate cyclase-activating adrenergic receptor signaling pathway(GO:0071880)
0.0 0.6 GO:0033273 response to vitamin(GO:0033273)
0.0 0.2 GO:0050915 sensory perception of sour taste(GO:0050915)
0.0 0.2 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.0 1.2 GO:0008156 negative regulation of DNA replication(GO:0008156)
0.0 0.8 GO:0045540 regulation of cholesterol biosynthetic process(GO:0045540)
0.0 0.6 GO:0006750 glutathione biosynthetic process(GO:0006750)
0.0 1.1 GO:0006302 double-strand break repair(GO:0006302)
0.0 0.5 GO:0046855 inositol phosphate dephosphorylation(GO:0046855)
0.0 1.1 GO:0035690 cellular response to drug(GO:0035690)
0.0 0.5 GO:0010867 positive regulation of triglyceride biosynthetic process(GO:0010867)
0.0 0.3 GO:0006013 mannose metabolic process(GO:0006013)
0.0 0.4 GO:0045176 apical protein localization(GO:0045176)
0.0 0.5 GO:0000281 mitotic cytokinesis(GO:0000281)
0.0 1.9 GO:0032729 positive regulation of interferon-gamma production(GO:0032729)
0.0 0.1 GO:0043928 exonucleolytic nuclear-transcribed mRNA catabolic process involved in deadenylation-dependent decay(GO:0043928)
0.0 0.3 GO:0006360 transcription from RNA polymerase I promoter(GO:0006360)
0.0 0.2 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0 0.2 GO:0036120 cellular response to platelet-derived growth factor stimulus(GO:0036120)
0.0 0.3 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.4 GO:0042135 neurotransmitter catabolic process(GO:0042135)
0.0 0.1 GO:2000474 opioid receptor signaling pathway(GO:0038003) regulation of opioid receptor signaling pathway(GO:2000474)
0.0 0.6 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.6 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 0.1 GO:0035563 positive regulation of chromatin binding(GO:0035563)
0.0 0.4 GO:0046500 S-adenosylmethionine metabolic process(GO:0046500)
0.0 0.9 GO:0021696 cerebellar cortex morphogenesis(GO:0021696)
0.0 0.6 GO:0030513 positive regulation of BMP signaling pathway(GO:0030513)
0.0 0.2 GO:0098792 xenophagy(GO:0098792)
0.0 0.8 GO:0007528 neuromuscular junction development(GO:0007528)
0.0 0.2 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.0 0.3 GO:0010884 positive regulation of lipid storage(GO:0010884)
0.0 0.5 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.0 0.7 GO:0007520 myoblast fusion(GO:0007520)
0.0 0.2 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.2 GO:0060148 positive regulation of posttranscriptional gene silencing(GO:0060148)
0.0 0.1 GO:0071800 podosome assembly(GO:0071800)
0.0 0.2 GO:0007398 ectoderm development(GO:0007398)
0.0 0.1 GO:0046326 positive regulation of glucose import(GO:0046326)
0.0 0.2 GO:0006656 phosphatidylcholine biosynthetic process(GO:0006656)
0.0 2.3 GO:0006457 protein folding(GO:0006457)
0.0 0.5 GO:0032728 positive regulation of interferon-beta production(GO:0032728)
0.0 0.9 GO:0006413 translational initiation(GO:0006413)
0.0 0.2 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 0.5 GO:0031929 TOR signaling(GO:0031929)
0.0 0.2 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.2 GO:0055070 copper ion homeostasis(GO:0055070)
0.0 0.2 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.0 0.1 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.0 0.2 GO:1900078 positive regulation of cellular response to insulin stimulus(GO:1900078)
0.0 0.1 GO:0051560 mitochondrial calcium ion homeostasis(GO:0051560)
0.0 0.2 GO:0007097 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.0 0.1 GO:0002710 negative regulation of T cell mediated immunity(GO:0002710)
0.0 0.6 GO:0006757 glycolytic process(GO:0006096) ATP generation from ADP(GO:0006757)
0.0 0.0 GO:0002302 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
3.6 14.6 GO:0000939 nuclear MIS12/MIND complex(GO:0000818) condensed chromosome inner kinetochore(GO:0000939)
3.6 10.8 GO:0042585 germinal vesicle(GO:0042585)
3.5 17.4 GO:0097226 sperm mitochondrial sheath(GO:0097226)
3.3 6.5 GO:0000799 nuclear condensin complex(GO:0000799)
2.4 14.7 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
1.9 13.0 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
1.8 5.4 GO:0005673 transcription factor TFIIE complex(GO:0005673)
1.8 23.3 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
1.8 10.7 GO:0005826 actomyosin contractile ring(GO:0005826)
1.7 8.7 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
1.7 8.7 GO:0048476 Holliday junction resolvase complex(GO:0048476)
1.6 4.9 GO:0031074 nucleocytoplasmic shuttling complex(GO:0031074)
1.6 17.7 GO:0005642 annulate lamellae(GO:0005642)
1.5 4.6 GO:0035061 interchromatin granule(GO:0035061)
1.5 10.7 GO:0000796 condensin complex(GO:0000796)
1.5 10.7 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
1.4 11.5 GO:0031415 NatA complex(GO:0031415)
1.4 8.2 GO:0098536 deuterosome(GO:0098536)
1.3 5.0 GO:0090661 box H/ACA telomerase RNP complex(GO:0090661)
1.2 13.3 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
1.1 8.0 GO:0001652 granular component(GO:0001652)
1.1 4.4 GO:0097450 astrocyte end-foot(GO:0097450)
1.1 7.7 GO:0033588 Elongator holoenzyme complex(GO:0033588)
1.0 8.2 GO:0001940 male pronucleus(GO:0001940)
1.0 5.1 GO:0071556 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.9 9.5 GO:0070545 PeBoW complex(GO:0070545)
0.9 2.8 GO:0055087 Ski complex(GO:0055087)
0.9 13.0 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.9 5.5 GO:0000235 astral microtubule(GO:0000235)
0.9 8.2 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.9 3.7 GO:0071942 XPC complex(GO:0071942)
0.9 8.2 GO:0000801 central element(GO:0000801)
0.9 4.5 GO:0001651 dense fibrillar component(GO:0001651)
0.9 2.7 GO:1990667 PCSK9-AnxA2 complex(GO:1990667)
0.8 4.1 GO:0097149 centralspindlin complex(GO:0097149)
0.8 4.1 GO:0031414 N-terminal protein acetyltransferase complex(GO:0031414)
0.8 8.9 GO:0070938 contractile ring(GO:0070938)
0.8 7.1 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.8 3.1 GO:0019034 viral replication complex(GO:0019034)
0.8 7.8 GO:0031080 nuclear pore outer ring(GO:0031080)
0.8 8.4 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.8 3.8 GO:0031262 Ndc80 complex(GO:0031262)
0.7 5.8 GO:0042382 paraspeckles(GO:0042382)
0.7 2.0 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.6 2.5 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.6 4.4 GO:0071204 histone pre-mRNA 3'end processing complex(GO:0071204)
0.6 1.9 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.6 4.4 GO:0097255 R2TP complex(GO:0097255)
0.6 4.9 GO:0070652 HAUS complex(GO:0070652)
0.6 3.0 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.6 6.0 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.6 4.2 GO:0005664 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.6 5.9 GO:0016272 prefoldin complex(GO:0016272)
0.6 1.8 GO:0033186 CAF-1 complex(GO:0033186)
0.6 27.9 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.6 3.5 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.6 4.6 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.6 2.9 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.6 6.7 GO:1990635 proximal dendrite(GO:1990635)
0.6 2.2 GO:0070552 BRISC complex(GO:0070552)
0.5 3.3 GO:0070522 ERCC4-ERCC1 complex(GO:0070522)
0.5 3.3 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.5 7.6 GO:0010369 chromocenter(GO:0010369)
0.5 5.4 GO:0032797 SMN complex(GO:0032797)
0.5 0.5 GO:1990257 piccolo-bassoon transport vesicle(GO:1990257)
0.5 5.9 GO:0031931 TORC1 complex(GO:0031931)
0.5 3.7 GO:0005827 polar microtubule(GO:0005827)
0.5 1.6 GO:0031251 PAN complex(GO:0031251)
0.5 2.1 GO:0032021 NELF complex(GO:0032021)
0.5 8.0 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.5 2.9 GO:0000798 nuclear cohesin complex(GO:0000798)
0.5 5.3 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.5 2.4 GO:0034719 pICln-Sm protein complex(GO:0034715) SMN-Sm protein complex(GO:0034719)
0.5 4.2 GO:0000243 commitment complex(GO:0000243)
0.5 6.0 GO:0071004 U2-type prespliceosome(GO:0071004)
0.5 9.3 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.4 3.1 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.4 55.5 GO:0000776 kinetochore(GO:0000776)
0.4 1.3 GO:0001939 female pronucleus(GO:0001939)
0.4 2.2 GO:0031523 Myb complex(GO:0031523)
0.4 6.0 GO:0001741 XY body(GO:0001741)
0.4 25.9 GO:0000775 chromosome, centromeric region(GO:0000775)
0.4 1.7 GO:0030681 ribonuclease P complex(GO:0030677) multimeric ribonuclease P complex(GO:0030681)
0.4 2.9 GO:0005726 perichromatin fibrils(GO:0005726)
0.4 1.7 GO:0005688 U6 snRNP(GO:0005688)
0.4 6.6 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.4 1.6 GO:0045251 mitochondrial electron transfer flavoprotein complex(GO:0017133) electron transfer flavoprotein complex(GO:0045251)
0.4 1.2 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.4 1.6 GO:1902636 kinociliary basal body(GO:1902636)
0.4 1.1 GO:0017109 glutamate-cysteine ligase complex(GO:0017109)
0.4 1.1 GO:0035101 FACT complex(GO:0035101)
0.4 1.8 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.4 3.7 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750)
0.3 1.4 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.3 2.0 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.3 1.7 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.3 1.0 GO:0098833 presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835)
0.3 4.0 GO:0042555 MCM complex(GO:0042555)
0.3 2.7 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.3 1.0 GO:0031533 mRNA cap methyltransferase complex(GO:0031533)
0.3 3.3 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.3 1.6 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.3 2.0 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.3 2.3 GO:0089701 U2AF(GO:0089701)
0.3 41.8 GO:0015934 large ribosomal subunit(GO:0015934)
0.3 2.9 GO:0032300 mismatch repair complex(GO:0032300)
0.3 0.6 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.3 0.9 GO:0000923 equatorial microtubule organizing center(GO:0000923)
0.3 1.5 GO:0000408 EKC/KEOPS complex(GO:0000408)
0.3 3.6 GO:0070852 cell body fiber(GO:0070852)
0.3 4.2 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.3 1.2 GO:0008274 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.3 1.2 GO:1903349 omegasome membrane(GO:1903349)
0.3 2.9 GO:0045120 pronucleus(GO:0045120)
0.3 1.2 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.3 2.9 GO:0042788 polysomal ribosome(GO:0042788)
0.3 0.6 GO:0033061 DNA recombinase mediator complex(GO:0033061)
0.3 1.7 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.3 3.7 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.3 0.5 GO:0031021 interphase microtubule organizing center(GO:0031021)
0.3 1.3 GO:0032444 activin responsive factor complex(GO:0032444)
0.3 1.8 GO:0005686 U2 snRNP(GO:0005686)
0.2 12.9 GO:0022626 cytosolic ribosome(GO:0022626)
0.2 9.4 GO:0005761 organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761)
0.2 1.2 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.2 2.9 GO:0044666 MLL3/4 complex(GO:0044666)
0.2 0.7 GO:0070069 cytochrome complex(GO:0070069)
0.2 4.1 GO:0031229 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.2 3.3 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.2 2.1 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.2 2.1 GO:0061574 ASAP complex(GO:0061574)
0.2 1.4 GO:0033010 paranodal junction(GO:0033010)
0.2 8.5 GO:0000791 euchromatin(GO:0000791)
0.2 1.1 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.2 4.4 GO:0005640 nuclear outer membrane(GO:0005640)
0.2 1.1 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.2 2.0 GO:0000439 core TFIIH complex(GO:0000439)
0.2 1.7 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.2 13.0 GO:0005643 nuclear pore(GO:0005643)
0.2 0.6 GO:0042642 actomyosin, myosin complex part(GO:0042642)
0.2 6.0 GO:0030992 intraciliary transport particle B(GO:0030992)
0.2 0.8 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.2 0.6 GO:0070531 BRCA1-A complex(GO:0070531)
0.2 3.2 GO:0035102 PRC1 complex(GO:0035102)
0.2 2.8 GO:0000930 gamma-tubulin complex(GO:0000930)
0.2 2.9 GO:0008385 IkappaB kinase complex(GO:0008385)
0.2 1.9 GO:0038201 TOR complex(GO:0038201)
0.2 3.2 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.2 8.4 GO:0045171 intercellular bridge(GO:0045171)
0.2 2.6 GO:0042575 DNA polymerase complex(GO:0042575)
0.2 2.4 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.2 2.4 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.2 8.5 GO:0030684 preribosome(GO:0030684)
0.2 0.7 GO:0036449 microtubule minus-end(GO:0036449)
0.2 8.4 GO:0016235 aggresome(GO:0016235)
0.2 0.7 GO:0043564 Ku70:Ku80 complex(GO:0043564)
0.2 0.9 GO:0044327 dendritic spine head(GO:0044327)
0.2 14.1 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.2 3.0 GO:0016580 Sin3 complex(GO:0016580)
0.2 0.3 GO:0001405 presequence translocase-associated import motor(GO:0001405)
0.2 2.4 GO:0071011 precatalytic spliceosome(GO:0071011)
0.2 2.7 GO:0032039 integrator complex(GO:0032039)
0.2 2.3 GO:0046540 U4/U6 x U5 tri-snRNP complex(GO:0046540)
0.2 5.3 GO:0070469 respiratory chain(GO:0070469)
0.2 0.5 GO:0071595 Nem1-Spo7 phosphatase complex(GO:0071595)
0.2 0.9 GO:0071141 SMAD protein complex(GO:0071141)
0.2 2.0 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.2 3.1 GO:0030056 hemidesmosome(GO:0030056)
0.1 0.4 GO:0005607 laminin-2 complex(GO:0005607)
0.1 1.5 GO:0034518 mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.1 0.7 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.1 0.9 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.1 0.7 GO:1990130 Iml1 complex(GO:1990130)
0.1 1.1 GO:0035145 exon-exon junction complex(GO:0035145)
0.1 1.1 GO:0035748 myelin sheath abaxonal region(GO:0035748)
0.1 3.6 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 2.8 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.1 1.8 GO:0000153 cytoplasmic ubiquitin ligase complex(GO:0000153)
0.1 0.5 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032) synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
0.1 0.4 GO:0044317 rod spherule(GO:0044317)
0.1 0.7 GO:0097361 CIA complex(GO:0097361)
0.1 0.5 GO:0098799 outer mitochondrial membrane protein complex(GO:0098799)
0.1 0.4 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.1 2.1 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.1 10.9 GO:0031594 neuromuscular junction(GO:0031594)
0.1 2.7 GO:0035267 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.1 1.4 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.1 0.4 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.1 2.7 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.1 2.4 GO:0005865 striated muscle thin filament(GO:0005865)
0.1 1.2 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.1 4.4 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.1 4.5 GO:0099738 cell cortex region(GO:0099738)
0.1 0.7 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.1 0.7 GO:0070847 core mediator complex(GO:0070847)
0.1 1.9 GO:0031045 dense core granule(GO:0031045)
0.1 0.4 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.1 2.0 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.1 0.6 GO:0005652 nuclear lamina(GO:0005652)
0.1 0.6 GO:0032437 cuticular plate(GO:0032437)
0.1 0.4 GO:1990075 periciliary membrane compartment(GO:1990075)
0.1 0.5 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.1 0.8 GO:0001673 male germ cell nucleus(GO:0001673)
0.1 0.7 GO:0000782 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.1 3.2 GO:0002102 podosome(GO:0002102)
0.1 0.9 GO:0016600 flotillin complex(GO:0016600)
0.1 64.6 GO:0005730 nucleolus(GO:0005730)
0.1 1.1 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.1 1.7 GO:0015030 Cajal body(GO:0015030)
0.1 0.5 GO:0000781 chromosome, telomeric region(GO:0000781)
0.1 0.8 GO:0031616 spindle pole centrosome(GO:0031616)
0.1 0.2 GO:0005869 dynactin complex(GO:0005869)
0.1 1.3 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.1 3.7 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 0.3 GO:0071547 piP-body(GO:0071547)
0.1 1.4 GO:0000145 exocyst(GO:0000145)
0.1 0.6 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.1 3.9 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.1 2.3 GO:0043034 costamere(GO:0043034)
0.1 0.8 GO:0031209 SCAR complex(GO:0031209)
0.1 1.0 GO:0097225 sperm midpiece(GO:0097225)
0.1 2.0 GO:0032153 cell division site(GO:0032153) cell division site part(GO:0032155)
0.1 2.7 GO:0000118 histone deacetylase complex(GO:0000118)
0.1 2.1 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.1 0.4 GO:0071012 catalytic step 1 spliceosome(GO:0071012)
0.1 0.4 GO:0030061 mitochondrial crista(GO:0030061)
0.1 1.2 GO:0097440 apical dendrite(GO:0097440)
0.1 4.8 GO:0016528 sarcoplasm(GO:0016528)
0.1 1.3 GO:0001917 photoreceptor inner segment(GO:0001917)
0.1 0.3 GO:0097422 tubular endosome(GO:0097422)
0.1 3.7 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.1 1.0 GO:0005680 anaphase-promoting complex(GO:0005680)
0.1 1.0 GO:0035686 sperm fibrous sheath(GO:0035686)
0.1 2.1 GO:0030131 clathrin adaptor complex(GO:0030131)
0.1 0.2 GO:0072379 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.1 4.4 GO:0017053 transcriptional repressor complex(GO:0017053)
0.1 4.8 GO:0005759 mitochondrial matrix(GO:0005759)
0.1 2.6 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.0 0.4 GO:0061617 MICOS complex(GO:0061617)
0.0 0.6 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.7 GO:0036038 MKS complex(GO:0036038)
0.0 0.2 GO:0043601 replisome(GO:0030894) nuclear replisome(GO:0043601)
0.0 1.0 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.7 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.8 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 0.8 GO:0005840 ribosome(GO:0005840)
0.0 0.8 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 1.1 GO:0032592 integral component of mitochondrial membrane(GO:0032592)
0.0 2.2 GO:0016605 PML body(GO:0016605)
0.0 9.3 GO:0016607 nuclear speck(GO:0016607)
0.0 2.4 GO:0042734 presynaptic membrane(GO:0042734)
0.0 2.7 GO:0030175 filopodium(GO:0030175)
0.0 0.3 GO:0097433 dense body(GO:0097433)
0.0 4.7 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 0.2 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.2 GO:0000214 tRNA-intron endonuclease complex(GO:0000214)
0.0 3.6 GO:0000151 ubiquitin ligase complex(GO:0000151)
0.0 0.3 GO:0042587 glycogen granule(GO:0042587)
0.0 0.6 GO:0002080 acrosomal membrane(GO:0002080)
0.0 0.2 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.0 0.3 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.2 GO:1990909 Wnt signalosome(GO:1990909)
0.0 1.1 GO:0000794 condensed nuclear chromosome(GO:0000794)
0.0 0.1 GO:0005675 holo TFIIH complex(GO:0005675)
0.0 0.3 GO:0030665 clathrin-coated vesicle membrane(GO:0030665)
0.0 0.7 GO:0060170 ciliary membrane(GO:0060170)
0.0 1.1 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.1 GO:0030132 clathrin coat of coated pit(GO:0030132)
0.0 1.3 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 0.1 GO:0045252 dihydrolipoyl dehydrogenase complex(GO:0045240) oxoglutarate dehydrogenase complex(GO:0045252)
0.0 1.1 GO:0005811 lipid particle(GO:0005811)
0.0 0.6 GO:0005681 spliceosomal complex(GO:0005681)
0.0 17.9 GO:0005739 mitochondrion(GO:0005739)
0.0 3.1 GO:0000228 nuclear chromosome(GO:0000228)
0.0 0.7 GO:0000786 nucleosome(GO:0000786)
0.0 0.6 GO:0000502 proteasome complex(GO:0000502)
0.0 0.1 GO:0048786 presynaptic active zone(GO:0048786)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
3.0 8.9 GO:0051765 inositol tetrakisphosphate kinase activity(GO:0051765)
2.9 17.4 GO:0002135 CTP binding(GO:0002135)
2.9 23.2 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
2.2 9.0 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
2.1 6.3 GO:0036470 tyrosine 3-monooxygenase activator activity(GO:0036470) L-dopa decarboxylase activator activity(GO:0036478)
1.8 10.8 GO:0044547 DNA topoisomerase binding(GO:0044547)
1.7 5.2 GO:0004619 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
1.6 9.7 GO:1990932 5.8S rRNA binding(GO:1990932)
1.6 9.5 GO:1990189 peptide-serine-N-acetyltransferase activity(GO:1990189)
1.5 4.6 GO:0010698 acetyltransferase activator activity(GO:0010698)
1.5 13.5 GO:0043023 ribosomal large subunit binding(GO:0043023)
1.5 4.4 GO:0004711 ribosomal protein S6 kinase activity(GO:0004711)
1.5 4.4 GO:0071207 histone pre-mRNA stem-loop binding(GO:0071207)
1.2 3.6 GO:0047751 3-oxo-5-alpha-steroid 4-dehydrogenase activity(GO:0003865) cholestenone 5-alpha-reductase activity(GO:0047751)
1.2 2.4 GO:0097677 STAT family protein binding(GO:0097677)
1.1 26.2 GO:0005540 hyaluronic acid binding(GO:0005540)
1.1 3.2 GO:0017108 5'-flap endonuclease activity(GO:0017108)
1.0 4.1 GO:0003883 CTP synthase activity(GO:0003883)
1.0 4.1 GO:0004427 inorganic diphosphatase activity(GO:0004427)
1.0 4.1 GO:0042903 tubulin deacetylase activity(GO:0042903)
1.0 9.1 GO:1990948 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
1.0 6.0 GO:0051425 PTB domain binding(GO:0051425)
1.0 2.9 GO:0004470 malic enzyme activity(GO:0004470) malate dehydrogenase (decarboxylating) (NAD+) activity(GO:0004471) malate dehydrogenase (decarboxylating) (NADP+) activity(GO:0004473)
1.0 4.9 GO:0031493 nucleosomal histone binding(GO:0031493)
1.0 2.9 GO:0008176 tRNA (guanine-N7-)-methyltransferase activity(GO:0008176)
1.0 9.5 GO:0001055 RNA polymerase II activity(GO:0001055)
0.9 4.7 GO:0043515 kinetochore binding(GO:0043515)
0.9 8.5 GO:0035174 histone serine kinase activity(GO:0035174)
0.9 7.4 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.9 8.2 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.9 2.7 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.9 3.5 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.9 2.7 GO:0034189 very-low-density lipoprotein particle binding(GO:0034189)
0.9 2.7 GO:0009918 sterol delta7 reductase activity(GO:0009918) 7-dehydrocholesterol reductase activity(GO:0047598)
0.9 7.8 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.8 13.4 GO:0017070 U6 snRNA binding(GO:0017070)
0.8 22.5 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.8 3.3 GO:0001884 pyrimidine nucleoside binding(GO:0001884)
0.8 5.8 GO:0032554 purine deoxyribonucleotide binding(GO:0032554)
0.8 2.4 GO:0003963 RNA-3'-phosphate cyclase activity(GO:0003963)
0.8 2.3 GO:0009383 rRNA (cytosine-C5-)-methyltransferase activity(GO:0009383)
0.8 4.5 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.7 2.2 GO:0008732 threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.7 2.2 GO:0000171 ribonuclease MRP activity(GO:0000171)
0.7 5.2 GO:0016428 tRNA (cytosine-5-)-methyltransferase activity(GO:0016428)
0.7 5.0 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.7 3.6 GO:0016649 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.7 4.2 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.7 2.7 GO:0035851 Krueppel-associated box domain binding(GO:0035851)
0.6 5.2 GO:0034511 U3 snoRNA binding(GO:0034511)
0.6 2.5 GO:0017057 6-phosphogluconolactonase activity(GO:0017057)
0.6 5.1 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.6 7.6 GO:0003958 NADPH-hemoprotein reductase activity(GO:0003958)
0.6 6.3 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.6 2.5 GO:0019237 centromeric DNA binding(GO:0019237)
0.6 1.9 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.6 2.5 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.6 1.8 GO:0023025 MHC class Ib protein complex binding(GO:0023025) MHC class Ib protein binding, via antigen binding groove(GO:0023030)
0.6 1.8 GO:0004816 asparagine-tRNA ligase activity(GO:0004816)
0.6 0.6 GO:0032138 single base insertion or deletion binding(GO:0032138)
0.6 1.7 GO:0097100 supercoiled DNA binding(GO:0097100)
0.6 2.9 GO:1990188 euchromatin binding(GO:1990188)
0.6 4.6 GO:0043199 sulfate binding(GO:0043199)
0.6 5.2 GO:0009008 DNA-methyltransferase activity(GO:0009008)
0.6 3.4 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.6 1.7 GO:0016532 superoxide dismutase copper chaperone activity(GO:0016532)
0.6 1.7 GO:0004492 methylmalonyl-CoA decarboxylase activity(GO:0004492)
0.6 3.9 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.6 13.4 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.6 1.7 GO:0015275 stretch-activated, cation-selective, calcium channel activity(GO:0015275)
0.5 4.4 GO:0001640 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640)
0.5 3.3 GO:0032356 oxidized DNA binding(GO:0032356) 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.5 0.5 GO:0051430 corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.5 1.6 GO:0001002 polymerase III regulatory region sequence-specific DNA binding(GO:0000992) RNA polymerase III type 1 promoter sequence-specific DNA binding(GO:0001002) RNA polymerase III type 2 promoter sequence-specific DNA binding(GO:0001003)
0.5 3.1 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.5 1.5 GO:0061711 N(6)-L-threonylcarbamoyladenine synthase(GO:0061711)
0.5 2.5 GO:0000150 recombinase activity(GO:0000150)
0.5 1.5 GO:0070137 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.5 0.5 GO:0032137 guanine/thymine mispair binding(GO:0032137)
0.5 2.4 GO:0002060 purine nucleobase binding(GO:0002060)
0.5 0.5 GO:0008169 C-methyltransferase activity(GO:0008169)
0.5 2.4 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.5 3.3 GO:0015616 DNA translocase activity(GO:0015616)
0.5 3.8 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.5 2.8 GO:0004126 cytidine deaminase activity(GO:0004126)
0.5 3.3 GO:0051880 G-quadruplex DNA binding(GO:0051880)
0.5 4.6 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.5 0.9 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.5 1.8 GO:0004832 valine-tRNA ligase activity(GO:0004832)
0.4 3.6 GO:1901612 cardiolipin binding(GO:1901612)
0.4 1.3 GO:0004829 threonine-tRNA ligase activity(GO:0004829)
0.4 1.8 GO:0002151 G-quadruplex RNA binding(GO:0002151)
0.4 0.9 GO:0051538 3 iron, 4 sulfur cluster binding(GO:0051538)
0.4 2.6 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.4 6.4 GO:0001164 RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.4 1.7 GO:0000700 mismatch base pair DNA N-glycosylase activity(GO:0000700) uracil DNA N-glycosylase activity(GO:0004844) deaminated base DNA N-glycosylase activity(GO:0097506)
0.4 1.6 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.4 1.2 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.4 4.4 GO:0070990 snRNP binding(GO:0070990)
0.4 6.0 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.4 4.4 GO:0102338 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.4 2.0 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.4 7.4 GO:0003746 translation elongation factor activity(GO:0003746)
0.4 1.1 GO:0004357 glutamate-cysteine ligase activity(GO:0004357)
0.4 1.1 GO:0016530 metallochaperone activity(GO:0016530)
0.4 1.5 GO:0004066 asparagine synthase (glutamine-hydrolyzing) activity(GO:0004066)
0.4 1.9 GO:0004849 uridine kinase activity(GO:0004849)
0.4 3.9 GO:0033170 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.4 1.8 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.3 8.4 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.3 30.3 GO:0003697 single-stranded DNA binding(GO:0003697)
0.3 2.0 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.3 2.7 GO:0004526 ribonuclease P activity(GO:0004526)
0.3 1.4 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.3 3.0 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.3 1.0 GO:0004482 mRNA (guanine-N7-)-methyltransferase activity(GO:0004482)
0.3 2.6 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.3 2.0 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.3 19.9 GO:0003743 translation initiation factor activity(GO:0003743)
0.3 1.6 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.3 9.4 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.3 5.5 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.3 9.6 GO:0043015 gamma-tubulin binding(GO:0043015)
0.3 3.2 GO:0016886 ligase activity, forming phosphoric ester bonds(GO:0016886)
0.3 0.9 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.3 6.6 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.3 0.9 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
0.3 1.2 GO:0004663 Rab geranylgeranyltransferase activity(GO:0004663)
0.3 9.1 GO:0070840 dynein complex binding(GO:0070840)
0.3 2.7 GO:0051011 microtubule minus-end binding(GO:0051011)
0.3 1.2 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.3 10.3 GO:0017091 AU-rich element binding(GO:0017091)
0.3 5.5 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.3 26.5 GO:0051082 unfolded protein binding(GO:0051082)
0.3 4.0 GO:1990226 histone methyltransferase binding(GO:1990226)
0.3 2.8 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.3 0.3 GO:0045503 dynein light chain binding(GO:0045503)
0.3 1.6 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.3 5.8 GO:0031698 beta-2 adrenergic receptor binding(GO:0031698)
0.3 1.1 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.3 1.8 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.3 1.8 GO:0000339 RNA cap binding(GO:0000339)
0.3 1.0 GO:0003998 acylphosphatase activity(GO:0003998)
0.3 6.5 GO:0004812 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.3 2.8 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.2 2.5 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.2 1.0 GO:0015266 protein channel activity(GO:0015266)
0.2 6.2 GO:0070064 proline-rich region binding(GO:0070064)
0.2 5.9 GO:0017160 Ral GTPase binding(GO:0017160)
0.2 2.4 GO:0003688 DNA replication origin binding(GO:0003688)
0.2 1.4 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.2 1.2 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.2 2.3 GO:0004521 endoribonuclease activity(GO:0004521)
0.2 1.6 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.2 36.0 GO:0003735 structural constituent of ribosome(GO:0003735)
0.2 0.7 GO:0008158 hedgehog receptor activity(GO:0008158)
0.2 1.6 GO:0008312 7S RNA binding(GO:0008312)
0.2 0.9 GO:0003681 bent DNA binding(GO:0003681)
0.2 1.1 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.2 1.6 GO:0015288 porin activity(GO:0015288)
0.2 1.7 GO:0031749 D2 dopamine receptor binding(GO:0031749)
0.2 1.2 GO:0008494 translation activator activity(GO:0008494)
0.2 0.8 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.2 0.6 GO:0004052 arachidonate 12-lipoxygenase activity(GO:0004052)
0.2 1.2 GO:0097001 ceramide binding(GO:0097001)
0.2 0.4 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
0.2 2.7 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.2 13.1 GO:0019894 kinesin binding(GO:0019894)
0.2 17.4 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.2 1.1 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.2 5.2 GO:1900750 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.2 4.9 GO:0016675 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.2 0.7 GO:1902379 chemoattractant activity involved in axon guidance(GO:1902379)
0.2 1.3 GO:0032184 SUMO polymer binding(GO:0032184)
0.2 1.6 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.2 6.6 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.2 1.1 GO:0070728 leucine binding(GO:0070728)
0.2 0.5 GO:0004487 methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
0.2 0.8 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.2 2.5 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.2 1.3 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.2 0.5 GO:0051747 cytosine C-5 DNA demethylase activity(GO:0051747)
0.2 0.5 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.2 0.3 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.2 0.6 GO:0017095 heparan sulfate 6-O-sulfotransferase activity(GO:0017095)
0.2 1.7 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.2 0.5 GO:0070122 isopeptidase activity(GO:0070122) ubiquitin-like protein-specific isopeptidase activity(GO:0070138) SUMO-specific isopeptidase activity(GO:0070140)
0.2 0.6 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.2 1.4 GO:0016929 SUMO-specific protease activity(GO:0016929)
0.2 1.7 GO:0042162 telomeric DNA binding(GO:0042162)
0.2 3.2 GO:0008143 poly(A) binding(GO:0008143)
0.2 1.2 GO:0044388 small protein activating enzyme binding(GO:0044388)
0.2 0.5 GO:0019776 Atg8 ligase activity(GO:0019776)
0.1 0.4 GO:0031403 lithium ion binding(GO:0031403)
0.1 1.0 GO:0061665 SUMO ligase activity(GO:0061665)
0.1 6.3 GO:0003684 damaged DNA binding(GO:0003684)
0.1 1.5 GO:0008379 thioredoxin peroxidase activity(GO:0008379)
0.1 0.7 GO:0008097 5S rRNA binding(GO:0008097)
0.1 2.7 GO:0001222 transcription corepressor binding(GO:0001222)
0.1 0.7 GO:0035241 protein-arginine omega-N monomethyltransferase activity(GO:0035241) histone methyltransferase activity (H4-R3 specific)(GO:0044020)
0.1 2.1 GO:0001056 RNA polymerase III activity(GO:0001056)
0.1 2.3 GO:0070628 proteasome binding(GO:0070628)
0.1 1.7 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.1 0.5 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.1 2.3 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.1 0.8 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.1 2.5 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.1 0.5 GO:0032896 palmitoyl-CoA 9-desaturase activity(GO:0032896)
0.1 0.4 GO:0036361 racemase and epimerase activity, acting on amino acids and derivatives(GO:0016855) racemase activity, acting on amino acids and derivatives(GO:0036361) amino-acid racemase activity(GO:0047661)
0.1 1.0 GO:0000182 rDNA binding(GO:0000182)
0.1 8.2 GO:0043021 ribonucleoprotein complex binding(GO:0043021)
0.1 0.6 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.1 0.6 GO:0042979 ornithine decarboxylase regulator activity(GO:0042979)
0.1 3.4 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 1.1 GO:0008649 rRNA methyltransferase activity(GO:0008649)
0.1 2.5 GO:0000049 tRNA binding(GO:0000049)
0.1 0.8 GO:1990405 protein antigen binding(GO:1990405)
0.1 4.3 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 1.3 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.1 1.2 GO:0015377 cation:chloride symporter activity(GO:0015377)
0.1 0.6 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.1 2.4 GO:0016279 lysine N-methyltransferase activity(GO:0016278) protein-lysine N-methyltransferase activity(GO:0016279)
0.1 1.3 GO:0016783 sulfurtransferase activity(GO:0016783)
0.1 1.2 GO:0016866 intramolecular transferase activity(GO:0016866)
0.1 0.7 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.1 0.7 GO:0031419 cobalamin binding(GO:0031419)
0.1 0.3 GO:0031127 galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127)
0.1 2.4 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.1 2.1 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.1 6.4 GO:0004004 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004)
0.1 0.6 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.1 0.7 GO:0001851 complement component C3b binding(GO:0001851)
0.1 0.5 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.1 1.6 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.1 0.4 GO:0004483 mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483)
0.1 0.2 GO:0004774 succinate-CoA ligase activity(GO:0004774)
0.1 2.3 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.1 6.7 GO:0004386 helicase activity(GO:0004386)
0.1 8.4 GO:0036459 thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.1 0.6 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.1 0.6 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.1 0.7 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.1 1.9 GO:0030332 cyclin binding(GO:0030332)
0.1 1.4 GO:0070402 NADPH binding(GO:0070402)
0.1 1.1 GO:0008242 omega peptidase activity(GO:0008242)
0.1 0.9 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.1 0.6 GO:0019211 phosphatase activator activity(GO:0019211)
0.1 1.1 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.1 1.6 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.1 0.9 GO:0017151 DEAD/H-box RNA helicase binding(GO:0017151)
0.1 1.6 GO:0016805 dipeptidase activity(GO:0016805)
0.1 1.9 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.1 0.6 GO:0016936 galactoside binding(GO:0016936)
0.1 0.8 GO:0030274 LIM domain binding(GO:0030274)
0.1 3.5 GO:0042169 SH2 domain binding(GO:0042169)
0.1 0.6 GO:0009374 biotin binding(GO:0009374)
0.1 0.5 GO:0032036 myosin heavy chain binding(GO:0032036)
0.1 2.1 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.1 0.7 GO:0015165 pyrimidine nucleotide-sugar transmembrane transporter activity(GO:0015165)
0.1 1.6 GO:0003951 NAD+ kinase activity(GO:0003951)
0.1 1.1 GO:0008173 RNA methyltransferase activity(GO:0008173)
0.1 1.0 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.1 0.5 GO:0001515 opioid peptide activity(GO:0001515)
0.1 0.4 GO:0043208 glycosphingolipid binding(GO:0043208)
0.1 0.3 GO:0034584 piRNA binding(GO:0034584)
0.1 1.5 GO:0036002 pre-mRNA binding(GO:0036002)
0.1 2.8 GO:0016831 carboxy-lyase activity(GO:0016831)
0.1 0.6 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.1 1.2 GO:0004622 lysophospholipase activity(GO:0004622)
0.1 0.3 GO:0034452 dynactin binding(GO:0034452)
0.1 0.9 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.1 0.2 GO:0016742 hydroxymethyl-, formyl- and related transferase activity(GO:0016742)
0.1 3.1 GO:0017080 sodium channel regulator activity(GO:0017080)
0.1 75.4 GO:0003723 RNA binding(GO:0003723)
0.1 1.7 GO:0051393 alpha-actinin binding(GO:0051393)
0.1 0.4 GO:0039706 co-receptor binding(GO:0039706)
0.1 2.4 GO:0004519 endonuclease activity(GO:0004519)
0.1 1.1 GO:0017049 GTP-Rho binding(GO:0017049)
0.1 2.9 GO:0097472 cyclin-dependent protein kinase activity(GO:0097472)
0.1 1.0 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.1 1.2 GO:0016780 phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.1 0.7 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.1 0.4 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.1 1.2 GO:0097602 cullin family protein binding(GO:0097602)
0.1 0.4 GO:0005499 vitamin D binding(GO:0005499)
0.1 0.9 GO:0032454 histone demethylase activity (H3-K9 specific)(GO:0032454)
0.1 0.2 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.1 0.9 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0 0.9 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 2.1 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.6 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.0 0.3 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.0 0.3 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.5 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 1.0 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.0 0.6 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.7 GO:0001106 RNA polymerase II transcription corepressor activity(GO:0001106)
0.0 0.9 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 2.6 GO:0008565 protein transporter activity(GO:0008565)
0.0 0.4 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.1 GO:0097003 adipokinetic hormone receptor activity(GO:0097003)
0.0 0.3 GO:0015037 peptide disulfide oxidoreductase activity(GO:0015037)
0.0 0.1 GO:0016898 D-lactate dehydrogenase (cytochrome) activity(GO:0004458) oxidoreductase activity, acting on the CH-OH group of donors, cytochrome as acceptor(GO:0016898)
0.0 2.0 GO:0015485 cholesterol binding(GO:0015485)
0.0 1.0 GO:0016878 acid-thiol ligase activity(GO:0016878)
0.0 3.7 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.5 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 1.8 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.0 0.1 GO:0016748 succinyltransferase activity(GO:0016748)
0.0 0.2 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.0 1.2 GO:0035064 methylated histone binding(GO:0035064)
0.0 1.6 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 0.4 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.6 GO:0005234 extracellular-glutamate-gated ion channel activity(GO:0005234)
0.0 0.6 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 1.1 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.6 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 1.3 GO:0030507 spectrin binding(GO:0030507)
0.0 0.3 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.6 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.0 11.9 GO:0004674 protein serine/threonine kinase activity(GO:0004674)
0.0 0.1 GO:0034602 oxoglutarate dehydrogenase (NAD+) activity(GO:0034602)
0.0 6.5 GO:0001227 transcriptional repressor activity, RNA polymerase II transcription regulatory region sequence-specific binding(GO:0001227)
0.0 2.1 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.3 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.3 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds(GO:0016799)
0.0 0.1 GO:0031800 type 3 metabotropic glutamate receptor binding(GO:0031800)
0.0 0.2 GO:0016308 1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0 5.0 GO:0061630 ubiquitin protein ligase activity(GO:0061630) ubiquitin-like protein ligase activity(GO:0061659)
0.0 0.2 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 0.7 GO:0005272 sodium channel activity(GO:0005272)
0.0 0.8 GO:0032947 protein complex scaffold(GO:0032947)
0.0 0.1 GO:0031996 thioesterase binding(GO:0031996)
0.0 3.5 GO:0004842 ubiquitin-protein transferase activity(GO:0004842)
0.0 0.2 GO:0015114 phosphate ion transmembrane transporter activity(GO:0015114)
0.0 1.7 GO:0005516 calmodulin binding(GO:0005516)
0.0 0.3 GO:0046965 retinoid X receptor binding(GO:0046965)
0.0 0.2 GO:0019825 oxygen binding(GO:0019825)
0.0 0.2 GO:0043531 ADP binding(GO:0043531)
0.0 0.3 GO:0005112 Notch binding(GO:0005112)
0.0 0.1 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.4 1.4 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
1.1 54.8 PID AURORA B PATHWAY Aurora B signaling
1.0 17.4 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.5 29.4 PID PLK1 PATHWAY PLK1 signaling events
0.4 1.8 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.4 6.7 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.4 3.1 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.2 0.2 PID MYC PATHWAY C-MYC pathway
0.2 3.8 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.2 15.4 PID TELOMERASE PATHWAY Regulation of Telomerase
0.2 22.8 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.2 6.3 PID ATR PATHWAY ATR signaling pathway
0.2 5.0 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.2 7.8 PID ATM PATHWAY ATM pathway
0.2 2.8 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.2 2.3 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.2 4.1 PID FANCONI PATHWAY Fanconi anemia pathway
0.2 7.6 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.1 4.0 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.1 6.5 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.1 0.9 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.1 1.2 PID BARD1 PATHWAY BARD1 signaling events
0.1 9.6 PID NOTCH PATHWAY Notch signaling pathway
0.1 5.0 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.1 0.3 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.1 4.1 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.1 4.3 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.1 5.2 PID E2F PATHWAY E2F transcription factor network
0.1 5.6 PID P53 REGULATION PATHWAY p53 pathway
0.1 1.0 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.1 0.9 PID ALK2 PATHWAY ALK2 signaling events
0.1 1.1 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.1 1.3 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.1 2.0 PID CD40 PATHWAY CD40/CD40L signaling
0.1 0.9 PID IL23 PATHWAY IL23-mediated signaling events
0.1 2.6 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.1 4.7 PID MTOR 4PATHWAY mTOR signaling pathway
0.1 3.4 PID HDAC CLASSI PATHWAY Signaling events mediated by HDAC Class I
0.1 2.3 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.1 1.1 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.1 0.4 PID AVB3 INTEGRIN PATHWAY Integrins in angiogenesis
0.1 0.9 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.1 0.5 PID S1P S1P2 PATHWAY S1P2 pathway
0.1 0.8 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.1 3.5 PID CMYB PATHWAY C-MYB transcription factor network
0.1 3.5 PID REG GR PATHWAY Glucocorticoid receptor regulatory network
0.1 4.3 PID AR PATHWAY Coregulation of Androgen receptor activity
0.1 2.3 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.1 0.8 PID CDC42 PATHWAY CDC42 signaling events
0.1 1.9 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 1.4 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.2 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.0 0.5 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 1.5 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.3 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.4 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.8 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.4 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 0.4 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 0.2 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.7 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 0.6 PID P73PATHWAY p73 transcription factor network
0.0 0.2 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.4 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 22.2 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
1.4 20.4 REACTOME ASSOCIATION OF LICENSING FACTORS WITH THE PRE REPLICATIVE COMPLEX Genes involved in Association of licensing factors with the pre-replicative complex
1.2 12.4 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
1.1 2.2 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
1.1 10.9 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
1.0 20.1 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.9 92.5 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.8 4.5 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.7 7.7 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.7 15.1 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.6 14.6 REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX Genes involved in Activation of the pre-replicative complex
0.6 10.6 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.6 13.0 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.5 5.9 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.5 16.6 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.5 17.0 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.5 4.1 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.5 26.4 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.5 5.8 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.5 20.5 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.5 6.1 REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.5 3.6 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.4 11.7 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.4 31.2 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.4 4.5 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.4 3.2 REACTOME SCFSKP2 MEDIATED DEGRADATION OF P27 P21 Genes involved in SCF(Skp2)-mediated degradation of p27/p21
0.4 3.0 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.4 2.2 REACTOME ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S Genes involved in Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
0.4 3.3 REACTOME FORMATION OF INCISION COMPLEX IN GG NER Genes involved in Formation of incision complex in GG-NER
0.4 5.3 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.4 5.3 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.3 8.6 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.3 2.1 REACTOME TRANSPORT OF MATURE MRNA DERIVED FROM AN INTRONLESS TRANSCRIPT Genes involved in Transport of Mature mRNA Derived from an Intronless Transcript
0.3 5.4 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.3 1.1 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.3 18.8 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.3 6.6 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.3 18.3 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.3 2.5 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.2 4.5 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.2 10.9 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.2 10.8 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.2 13.7 REACTOME MITOTIC G2 G2 M PHASES Genes involved in Mitotic G2-G2/M phases
0.2 5.1 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.2 10.4 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS Genes involved in CREB phosphorylation through the activation of Ras
0.2 12.7 REACTOME DNA REPAIR Genes involved in DNA Repair
0.2 5.2 REACTOME TRNA AMINOACYLATION Genes involved in tRNA Aminoacylation
0.2 4.1 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.2 1.7 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.2 3.2 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.2 2.3 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.2 2.7 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.2 0.5 REACTOME GASTRIN CREB SIGNALLING PATHWAY VIA PKC AND MAPK Genes involved in Gastrin-CREB signalling pathway via PKC and MAPK
0.2 2.2 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.2 15.6 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.2 3.0 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.2 3.8 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1 2.6 REACTOME P130CAS LINKAGE TO MAPK SIGNALING FOR INTEGRINS Genes involved in p130Cas linkage to MAPK signaling for integrins
0.1 2.3 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.1 2.6 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.1 3.9 REACTOME SYNTHESIS OF VERY LONG CHAIN FATTY ACYL COAS Genes involved in Synthesis of very long-chain fatty acyl-CoAs
0.1 0.6 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.1 0.4 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.1 1.6 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.1 5.3 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.1 2.3 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.1 3.7 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.1 1.7 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.1 0.9 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.1 1.2 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.1 0.9 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.1 1.2 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.1 1.9 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.1 3.1 REACTOME TGF BETA RECEPTOR SIGNALING ACTIVATES SMADS Genes involved in TGF-beta receptor signaling activates SMADs
0.1 1.4 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.1 0.6 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.1 4.7 REACTOME TRANSLATION Genes involved in Translation
0.1 2.7 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.1 0.7 REACTOME INTEGRATION OF PROVIRUS Genes involved in Integration of provirus
0.1 5.4 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.1 2.0 REACTOME RNA POL I TRANSCRIPTION Genes involved in RNA Polymerase I Transcription
0.1 0.4 REACTOME INFLUENZA LIFE CYCLE Genes involved in Influenza Life Cycle
0.1 1.0 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 1.3 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.1 2.2 REACTOME LATE PHASE OF HIV LIFE CYCLE Genes involved in Late Phase of HIV Life Cycle
0.1 1.6 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.1 1.1 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1 2.4 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.1 1.9 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.1 0.7 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.1 1.6 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.1 0.8 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.1 0.7 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.1 0.8 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.2 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.3 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.5 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.0 0.1 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.5 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 0.5 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.7 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 1.0 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.5 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0 0.9 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.3 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 0.8 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.6 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 0.6 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.8 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.4 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.5 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 0.6 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.8 REACTOME TRIGLYCERIDE BIOSYNTHESIS Genes involved in Triglyceride Biosynthesis
0.0 0.1 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.0 0.8 REACTOME INHIBITION OF INSULIN SECRETION BY ADRENALINE NORADRENALINE Genes involved in Inhibition of Insulin Secretion by Adrenaline/Noradrenaline
0.0 0.4 REACTOME KINESINS Genes involved in Kinesins
0.0 0.2 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.1 REACTOME SIGNALING BY EGFR IN CANCER Genes involved in Signaling by EGFR in Cancer
0.0 0.2 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.1 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.2 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC