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2D miR_HR1_12

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Results for Nr6a1

Z-value: 0.53

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Transcription factors associated with Nr6a1

Gene Symbol Gene ID Gene Info
ENSMUSG00000063972.7 nuclear receptor subfamily 6, group A, member 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Nr6a1mm10_v2_chr2_-_38926217_38926454-0.382.3e-01Click!

Activity profile of Nr6a1 motif

Sorted Z-values of Nr6a1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr16_+_17276291 1.19 ENSMUST00000164950.1
ENSMUST00000159242.1
transmembrane protein 191C
chr16_+_17276337 1.14 ENSMUST00000159065.1
ENSMUST00000159494.1
ENSMUST00000159811.1
transmembrane protein 191C
chr9_+_87144285 0.99 ENSMUST00000113149.1
ENSMUST00000143779.1
ENSMUST00000179313.1
ENSMUST00000049457.7
ENSMUST00000153444.1
melanocortin 2 receptor accessory protein 2
chr15_+_31572179 0.66 ENSMUST00000161088.1
carboxymethylenebutenolidase-like (Pseudomonas)
chr6_+_42245907 0.63 ENSMUST00000031897.5
glutathione S-transferase kappa 1
chr9_-_96437434 0.58 ENSMUST00000070500.2
cDNA sequence BC043934
chr7_-_66427469 0.51 ENSMUST00000015278.7
aldehyde dehydrogenase family 1, subfamily A3
chrX_-_8018492 0.49 ENSMUST00000033503.2
glyoxalase domain containing 5
chr17_+_72918298 0.49 ENSMUST00000024857.6
limb-bud and heart
chr17_-_57228003 0.47 ENSMUST00000177046.1
ENSMUST00000024988.8
complement component 3
chr4_+_43632185 0.47 ENSMUST00000107874.2
natriuretic peptide receptor 2
chr7_+_16944645 0.44 ENSMUST00000094807.5
PNMA-like 2
chr4_-_45530330 0.42 ENSMUST00000061986.5
src homology 2 domain-containing transforming protein B
chr14_+_58072686 0.42 ENSMUST00000022545.7
fibroblast growth factor 9
chr2_-_127729872 0.41 ENSMUST00000028856.2
mal, T cell differentiation protein-like
chr5_-_5694559 0.39 ENSMUST00000115426.2
six transmembrane epithelial antigen of prostate 2
chr4_-_123904826 0.34 ENSMUST00000181292.1
predicted gene, 26606
chr16_+_10170216 0.34 ENSMUST00000121292.1
ribosomal protein L39-like
chr6_-_124636085 0.32 ENSMUST00000068797.2
predicted gene 5077
chr15_-_58364148 0.31 ENSMUST00000068515.7
annexin A13
chr5_-_137611372 0.31 ENSMUST00000054564.6
procollagen C-endopeptidase enhancer protein
chr5_-_5694024 0.30 ENSMUST00000115425.2
ENSMUST00000115427.1
ENSMUST00000115424.2
ENSMUST00000015797.4
six transmembrane epithelial antigen of prostate 2
chr9_+_73101836 0.29 ENSMUST00000172578.1
KH domain containing 3, subcortical maternal complex member
chr17_-_46645128 0.29 ENSMUST00000003642.6
kinesin light chain 4
chr5_-_137611429 0.28 ENSMUST00000031731.7
procollagen C-endopeptidase enhancer protein
chr16_+_10170228 0.27 ENSMUST00000044103.5
ribosomal protein L39-like
chr5_-_137610626 0.25 ENSMUST00000142675.1
procollagen C-endopeptidase enhancer protein
chr5_+_136987019 0.24 ENSMUST00000004968.4
procollagen-lysine, 2-oxoglutarate 5-dioxygenase 3
chr10_-_68541842 0.23 ENSMUST00000020103.2
RIKEN cDNA 1700040L02 gene
chr5_-_136986829 0.21 ENSMUST00000034953.7
ENSMUST00000085941.5
zinc finger, HIT domain containing 1
chr5_-_5694269 0.20 ENSMUST00000148333.1
six transmembrane epithelial antigen of prostate 2
chr11_-_69822144 0.19 ENSMUST00000045771.6
sperm maturation 1
chr5_-_108674753 0.19 ENSMUST00000119270.1
ENSMUST00000163328.1
ENSMUST00000136227.1
solute carrier family 26 (sulfate transporter), member 1
chr11_-_99244058 0.19 ENSMUST00000103132.3
ENSMUST00000038214.6
keratin 222
chr9_+_53301571 0.19 ENSMUST00000051014.1
exophilin 5
chr4_-_125065603 0.17 ENSMUST00000036383.3
dynein, axonemal, light intermediate polypeptide 1
chr4_-_134552122 0.17 ENSMUST00000060435.6
selenoprotein N, 1
chr9_-_119157055 0.17 ENSMUST00000010795.4
acetyl-Coenzyme A acyltransferase 1B
chr9_+_122805524 0.16 ENSMUST00000052740.7
T cell activation inhibitor, mitochondrial
chr1_+_82724909 0.16 ENSMUST00000073025.5
ENSMUST00000161648.1
ENSMUST00000160786.1
ENSMUST00000162003.1
mitochondrial fission factor
chr10_+_21978643 0.15 ENSMUST00000142174.1
ENSMUST00000164659.1
serum/glucocorticoid regulated kinase 1
chr4_-_139131058 0.14 ENSMUST00000143971.1
mitochondrial inner membrane organizing system 1
chr9_-_121839460 0.13 ENSMUST00000135986.2
coiled-coil domain containing 13
chr2_+_157424255 0.13 ENSMUST00000029175.7
ENSMUST00000092576.4
Rous sarcoma oncogene
chr4_-_82505274 0.13 ENSMUST00000050872.8
ENSMUST00000064770.2
nuclear factor I/B
chr17_+_33629078 0.12 ENSMUST00000166627.1
ENSMUST00000073570.5
ENSMUST00000170225.1
zinc finger protein 414
chr2_+_127425155 0.11 ENSMUST00000062211.3
ENSMUST00000110373.1
glycerol-3-phosphate acyltransferase 2, mitochondrial
chr4_+_138434647 0.10 ENSMUST00000044058.4
ENSMUST00000105813.1
ENSMUST00000105815.1
mitochondrial ubiquitin ligase activator of NFKB 1
chr7_-_145283915 0.10 ENSMUST00000058022.4
two pore segment channel 2
chr5_+_114175889 0.10 ENSMUST00000146841.1
acetyl-Coenzyme A carboxylase beta
chr9_+_50603892 0.08 ENSMUST00000044051.4
translocase of inner mitochondrial membrane 8B
chr7_+_128265675 0.08 ENSMUST00000118169.1
ENSMUST00000142841.1
solute carrier family 5 (sodium/glucose cotransporter), member 2
chr16_-_3718105 0.08 ENSMUST00000023180.7
ENSMUST00000100222.2
Mediterranean fever
chr6_+_135198034 0.07 ENSMUST00000130612.1
RIKEN cDNA 8430419L09 gene
chr2_+_176431829 0.06 ENSMUST00000172025.1
predicted gene 14435
chr13_+_25056004 0.06 ENSMUST00000036932.8
doublecortin domain containing 2a
chr2_+_172472512 0.05 ENSMUST00000029007.2
family with sequence similarity 209
chr2_+_173737492 0.05 ENSMUST00000067530.4
vesicle-associated membrane protein, associated protein B and C
chr10_-_79916912 0.05 ENSMUST00000045628.7
ENSMUST00000171416.1
R3H domain containing 4
chr6_+_135197977 0.05 ENSMUST00000111915.1
ENSMUST00000111916.1
RIKEN cDNA 8430419L09 gene
chr6_-_57535422 0.05 ENSMUST00000042766.3
protein phosphatase 1K (PP2C domain containing)
chr7_-_140881811 0.04 ENSMUST00000106048.3
ENSMUST00000147331.2
ENSMUST00000137710.1
sirtuin 3
chr19_-_5688149 0.04 ENSMUST00000068169.5
pecanex-like 3 (Drosophila)
chr11_+_6560183 0.04 ENSMUST00000109722.2
cerebral cavernous malformation 2
chr14_+_76488436 0.03 ENSMUST00000101618.2
TSC22 domain family, member 1
chr16_+_11322876 0.03 ENSMUST00000180792.1
sorting nexin 29
chr15_+_100038635 0.03 ENSMUST00000100203.3
DIP2 disco-interacting protein 2 homolog B (Drosophila)
chr2_+_32606946 0.03 ENSMUST00000113290.1
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
chr2_+_177768044 0.03 ENSMUST00000108942.3
predicted gene 14322
chr4_+_123904907 0.03 ENSMUST00000106202.3
c-myc binding protein
chr17_-_46831413 0.02 ENSMUST00000040624.5
GLTSCR1-like
chr1_+_151428612 0.02 ENSMUST00000065625.5
tRNA methyltransferase 1 like
chr7_+_133637686 0.02 ENSMUST00000128901.2
RIKEN cDNA 2700050L05 gene
chr6_+_71293765 0.02 ENSMUST00000114185.2
predicted gene 1070
chr1_+_171329015 0.02 ENSMUST00000111300.1
death effector domain-containing
chr6_-_129622685 0.02 ENSMUST00000032252.5
killer cell lectin-like receptor subfamily K, member 1
chr11_-_100770926 0.02 ENSMUST00000139341.1
ENSMUST00000017891.7
GH3 domain containing
chr4_-_82505749 0.02 ENSMUST00000107245.2
ENSMUST00000107246.1
nuclear factor I/B
chr7_+_133637543 0.02 ENSMUST00000051169.6
RIKEN cDNA 2700050L05 gene
chr9_+_98296556 0.02 ENSMUST00000035031.6
ENSMUST00000112935.1
nicotinamide nucleotide adenylyltransferase 3
chr14_+_78849171 0.02 ENSMUST00000040990.5
von Willebrand factor A domain containing 8
chr16_+_11322915 0.01 ENSMUST00000115814.3
sorting nexin 29
chrX_-_60147643 0.01 ENSMUST00000033478.4
ENSMUST00000101531.3
mcf.2 transforming sequence
chr14_-_121505247 0.01 ENSMUST00000088386.6
solute carrier family 15 (oligopeptide transporter), member 1
chr11_+_120677226 0.01 ENSMUST00000129644.2
ENSMUST00000151160.1
alveolar soft part sarcoma chromosome region, candidate 1 (human)
chr12_+_3807076 0.00 ENSMUST00000174817.1
DNA methyltransferase 3A
chr1_+_131970589 0.00 ENSMUST00000027695.6
solute carrier family 45, member 3
chr9_-_50603792 0.00 ENSMUST00000000175.4
succinate dehydrogenase complex, subunit D, integral membrane protein

Network of associatons between targets according to the STRING database.

First level regulatory network of Nr6a1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0060166 olfactory pit development(GO:0060166)
0.1 0.5 GO:0001970 positive regulation of activation of membrane attack complex(GO:0001970)
0.1 0.9 GO:0098706 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.1 0.9 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.1 0.5 GO:1904672 regulation of somatic stem cell population maintenance(GO:1904672)
0.1 0.2 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.1 0.4 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.0 0.2 GO:0019532 oxalate transport(GO:0019532)
0.0 0.1 GO:0046949 fatty-acyl-CoA biosynthetic process(GO:0046949) malonyl-CoA metabolic process(GO:2001293)
0.0 0.2 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.0 0.2 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
0.0 0.1 GO:0071608 macrophage inflammatory protein-1 alpha production(GO:0071608)
0.0 0.1 GO:0051902 negative regulation of mitochondrial depolarization(GO:0051902)
0.0 0.4 GO:0030238 male sex determination(GO:0030238)
0.0 0.1 GO:1904925 negative regulation of mitochondrial fusion(GO:0010637) negative regulation of defense response to virus by host(GO:0050689) regulation of chemokine (C-C motif) ligand 5 production(GO:0071649) positive regulation of macromitophagy(GO:1901526) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925)
0.0 0.2 GO:1900244 positive regulation of synaptic vesicle endocytosis(GO:1900244)
0.0 1.0 GO:0097009 energy homeostasis(GO:0097009)
0.0 0.1 GO:0044830 modulation by host of viral RNA genome replication(GO:0044830)
0.0 0.1 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
0.0 0.2 GO:0043402 glucocorticoid mediated signaling pathway(GO:0043402)
0.0 0.0 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.9 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.5 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.2 GO:0000812 Swr1 complex(GO:0000812)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0070996 type 1 melanocortin receptor binding(GO:0070996)
0.1 0.9 GO:0052851 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.1 0.5 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.1 0.5 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.1 0.2 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.0 0.4 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.3 GO:1901611 phosphatidylglycerol binding(GO:1901611)
0.0 0.6 GO:0015035 protein disulfide oxidoreductase activity(GO:0015035)
0.0 0.1 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.0 0.2 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.0 0.1 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.0 0.8 GO:0016504 peptidase activator activity(GO:0016504)
0.0 0.4 GO:0005104 fibroblast growth factor receptor binding(GO:0005104)
0.0 0.2 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.1 GO:0071253 connexin binding(GO:0071253)
0.0 0.2 GO:0003988 acetyl-CoA C-acyltransferase activity(GO:0003988)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.4 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.4 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.0 1.1 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.3 REACTOME KINESINS Genes involved in Kinesins