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2D miR_HR1_12

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Results for Neurog2

Z-value: 1.27

Motif logo

Transcription factors associated with Neurog2

Gene Symbol Gene ID Gene Info
ENSMUSG00000027967.7 neurogenin 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Neurog2mm10_v2_chr3_+_127633134_1276331400.745.6e-03Click!

Activity profile of Neurog2 motif

Sorted Z-values of Neurog2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr9_-_70421533 3.65 ENSMUST00000034742.6
cyclin B2
chr7_+_30458280 2.76 ENSMUST00000126297.1
nephrosis 1, nephrin
chr3_-_123236134 1.96 ENSMUST00000106427.1
ENSMUST00000106426.1
ENSMUST00000051443.5
synaptopodin 2
chr19_+_7268296 1.91 ENSMUST00000066646.4
REST corepressor 2
chr14_+_3825596 1.83 ENSMUST00000178256.1
predicted gene 3002
chr19_-_53371766 1.83 ENSMUST00000086887.1
predicted gene 10197
chr14_+_3667518 1.75 ENSMUST00000112801.3
predicted gene 3020
chr14_-_5801530 1.69 ENSMUST00000178414.1
predicted gene 3383
chr14_+_5164535 1.67 ENSMUST00000179659.1
predicted gene 3317
chr14_-_6266620 1.62 ENSMUST00000096172.5
predicted gene 3411
chr14_+_5517172 1.61 ENSMUST00000178220.1
predicted gene, 3488
chr14_-_5449039 1.60 ENSMUST00000180143.1
predicted gene 3194
chr9_+_26999668 1.58 ENSMUST00000039161.8
thymocyte nuclear protein 1
chr2_+_118772766 1.58 ENSMUST00000130293.1
ENSMUST00000061360.3
proline/histidine/glycine-rich 1
chr16_+_10835046 1.46 ENSMUST00000037913.8
RMI2, RecQ mediated genome instability 2, homolog (S. cerevisiae)
chr7_-_44748306 1.44 ENSMUST00000118162.1
ENSMUST00000140599.2
ENSMUST00000120798.1
zinc finger protein 473
chrX_-_111537947 1.43 ENSMUST00000132319.1
ENSMUST00000123951.1
ribosomal protein S6 kinase polypeptide 6
chr10_+_128232065 1.42 ENSMUST00000055539.4
ENSMUST00000105244.1
ENSMUST00000105243.2
ENSMUST00000125289.1
ENSMUST00000105242.1
timeless circadian clock 1
chr9_+_106281061 1.39 ENSMUST00000072206.6
POC1 centriolar protein homolog A (Chlamydomonas)
chr14_+_4871156 1.36 ENSMUST00000166410.2
predicted gene 3264
chr7_-_64392214 1.36 ENSMUST00000032735.5
M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein)
chr1_+_6730135 1.35 ENSMUST00000155921.1
suppression of tumorigenicity 18
chr4_+_155839675 1.34 ENSMUST00000141883.1
matrix-remodelling associated 8
chr4_+_11579647 1.24 ENSMUST00000180239.1
fibrinogen silencer binding protein
chr7_+_30699783 1.20 ENSMUST00000013227.7
RIKEN cDNA 2200002J24 gene
chr14_+_4430992 1.15 ENSMUST00000164603.1
ENSMUST00000166848.1
predicted gene 3173
chr9_+_66946057 1.14 ENSMUST00000040917.7
ENSMUST00000127896.1
ribosomal protein S27-like
chr9_+_108560422 1.14 ENSMUST00000081111.8
inosine 5'-phosphate dehydrogenase 2
chrX_+_36328353 1.13 ENSMUST00000016383.3
LON peptidase N-terminal domain and ring finger 3
chr1_-_74749221 1.11 ENSMUST00000081636.6
protein kinase, AMP-activated, gamma 3 non-catatlytic subunit
chr7_-_126704736 1.09 ENSMUST00000131415.1
coronin, actin binding protein 1A
chr14_+_4514758 1.08 ENSMUST00000112776.2
predicted gene 3173
chr14_-_6741430 1.04 ENSMUST00000100904.4
predicted gene 3636
chr7_-_126704816 1.03 ENSMUST00000032949.7
coronin, actin binding protein 1A
chr8_+_85492568 0.99 ENSMUST00000034136.5
glutamic pyruvate transaminase (alanine aminotransferase) 2
chr2_-_105399286 0.96 ENSMUST00000006128.6
reticulocalbin 1
chr8_+_122476196 0.94 ENSMUST00000146634.1
ENSMUST00000134127.1
cytosolic thiouridylase subunit 2 homolog (S. pombe)
chr11_-_75796048 0.93 ENSMUST00000021209.7
double C2, beta
chrX_+_56786527 0.92 ENSMUST00000144600.1
four and a half LIM domains 1
chr11_+_69015911 0.91 ENSMUST00000021278.7
ENSMUST00000161455.1
ENSMUST00000116359.2
CTS telomere maintenance complex component 1
chr16_+_16213318 0.86 ENSMUST00000162150.1
ENSMUST00000161342.1
ENSMUST00000039408.2
plakophilin 2
chr15_+_78913916 0.85 ENSMUST00000089378.4
pyridoxal (pyridoxine, vitamin B6) phosphatase
chr7_-_44748049 0.84 ENSMUST00000120074.1
zinc finger protein 473
chr1_-_155232710 0.81 ENSMUST00000035914.3
cDNA sequence BC034090
chr7_-_126704522 0.80 ENSMUST00000135087.1
coronin, actin binding protein 1A
chr3_-_107333289 0.78 ENSMUST00000061772.9
RNA binding motif protein 15
chr17_-_35969724 0.75 ENSMUST00000043757.8
ATP-binding cassette, sub-family F (GCN20), member 1
chr4_+_127172866 0.75 ENSMUST00000106094.2
discs, large (Drosophila) homolog-associated protein 3
chr14_+_3225315 0.73 ENSMUST00000178670.1
RIKEN cDNA D830030K20 gene
chr6_+_83034173 0.72 ENSMUST00000000707.2
ENSMUST00000101257.3
lysyl oxidase-like 3
chr9_-_71896047 0.70 ENSMUST00000184448.1
transcription factor 12
chr13_-_97747399 0.70 ENSMUST00000144993.1
RIKEN cDNA 5330416C01 gene
chr10_+_110920170 0.69 ENSMUST00000020403.5
cysteine and glycine-rich protein 2
chr2_+_69670100 0.69 ENSMUST00000100050.3
kelch-like 41
chr3_-_63899437 0.66 ENSMUST00000159188.1
ENSMUST00000177143.1
phospholipase C, eta 1
chr3_-_63851251 0.64 ENSMUST00000162269.2
ENSMUST00000159676.2
ENSMUST00000175947.1
phospholipase C, eta 1
chr4_+_9269285 0.64 ENSMUST00000038841.7
clavesin 1
chr2_+_127587214 0.63 ENSMUST00000028852.6
mitochondrial ribosomal protein S5
chr9_+_35669624 0.62 ENSMUST00000118254.1
prostate and testis expressed 2
chr11_-_97782377 0.62 ENSMUST00000128801.1
ribosomal protein L23
chr3_-_63899373 0.61 ENSMUST00000161052.2
phospholipase C, eta 1
chr8_+_122476143 0.61 ENSMUST00000116412.1
cytosolic thiouridylase subunit 2 homolog (S. pombe)
chr10_-_127522428 0.59 ENSMUST00000026470.4
serine hydroxymethyltransferase 2 (mitochondrial)
chr11_-_84916338 0.59 ENSMUST00000103195.4
zinc finger, HIT type 3
chr5_+_124483458 0.57 ENSMUST00000111453.1
small nuclear ribonucleoprotein 35 (U11/U12)
chr13_+_16014457 0.57 ENSMUST00000164993.1
inhibin beta-A
chr11_-_69920892 0.56 ENSMUST00000152589.1
ENSMUST00000108612.1
ENSMUST00000108611.1
eukaryotic translation initiation factor 5A
chr5_-_135962265 0.55 ENSMUST00000111150.1
scavenger receptor cysteine rich domain containing, group B (4 domains)
chr16_-_44333135 0.55 ENSMUST00000047446.6
SID1 transmembrane family, member 1
chrX_+_7579666 0.54 ENSMUST00000115740.1
ENSMUST00000115739.1
forkhead box P3
chr11_-_97782409 0.53 ENSMUST00000103146.4
ribosomal protein L23
chr18_-_7297901 0.53 ENSMUST00000081275.4
armadillo repeat containing 4
chr4_-_141598206 0.53 ENSMUST00000131317.1
ENSMUST00000006381.4
ENSMUST00000129602.1
filamin binding LIM protein 1
chr15_-_77970750 0.52 ENSMUST00000100484.4
eukaryotic translation initiation factor 3, subunit D
chr1_+_6730051 0.52 ENSMUST00000043578.6
ENSMUST00000131467.1
ENSMUST00000150761.1
ENSMUST00000151281.1
suppression of tumorigenicity 18
chr6_-_148831395 0.52 ENSMUST00000145960.1
importin 8
chr14_-_70167973 0.51 ENSMUST00000125300.1
PDZ and LIM domain 2
chr4_+_33078796 0.51 ENSMUST00000131920.1
gamma-aminobutyric acid (GABA) C receptor, subunit rho 2
chr7_+_30314810 0.51 ENSMUST00000054594.8
ENSMUST00000177078.1
ENSMUST00000176504.1
ENSMUST00000176304.1
spectrin repeat containing, nuclear envelope family member 4
chr2_+_24345282 0.49 ENSMUST00000114485.2
interleukin 1 receptor antagonist
chr2_-_80128834 0.48 ENSMUST00000102654.4
ENSMUST00000102655.3
phosphodiesterase 1A, calmodulin-dependent
chr1_+_150392794 0.47 ENSMUST00000124973.2
translocated promoter region
chr2_+_75832168 0.46 ENSMUST00000047232.7
ENSMUST00000111952.2
alkylglycerone phosphate synthase
chr2_-_132111440 0.46 ENSMUST00000128899.1
solute carrier family 23 (nucleobase transporters), member 2
chr5_-_135962275 0.45 ENSMUST00000054895.3
scavenger receptor cysteine rich domain containing, group B (4 domains)
chr4_-_82850721 0.45 ENSMUST00000139401.1
zinc finger, DHHC domain containing 21
chr12_-_73286698 0.44 ENSMUST00000116420.2
TRM5 tRNA methyltransferase 5
chr16_-_75909272 0.42 ENSMUST00000114239.2
SAM domain, SH3 domain and nuclear localization signals, 1
chr10_+_80142358 0.40 ENSMUST00000105366.1
ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit
chr14_+_3428103 0.40 ENSMUST00000178060.1
predicted gene 3005
chr10_+_80142295 0.40 ENSMUST00000003156.8
ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit
chr3_+_54156039 0.39 ENSMUST00000029311.6
transient receptor potential cation channel, subfamily C, member 4
chr1_+_15287259 0.39 ENSMUST00000175681.1
potassium voltage gated channel, Shab-related subfamily, member 2
chr19_+_37207528 0.38 ENSMUST00000024078.7
ENSMUST00000112391.1
membrane-associated ring finger (C3HC4) 5
chr8_+_85171322 0.38 ENSMUST00000076896.5
predicted gene 6531
chr5_+_124194894 0.38 ENSMUST00000159053.1
ENSMUST00000162577.1
predicted gene 16338
chr15_-_91191733 0.37 ENSMUST00000069511.6
ATP-binding cassette, sub-family D (ALD), member 2
chr6_+_51544513 0.37 ENSMUST00000179365.1
ENSMUST00000114439.1
sorting nexin 10
chr2_-_80129458 0.37 ENSMUST00000102653.1
phosphodiesterase 1A, calmodulin-dependent
chr2_-_79456750 0.35 ENSMUST00000041099.4
neurogenic differentiation 1
chr2_-_71367749 0.34 ENSMUST00000151937.1
solute carrier family 25 (mitochondrial carrier, Aralar), member 12
chr2_-_164473714 0.34 ENSMUST00000017864.2
transformation related protein 53 target 5
chr1_-_74304120 0.33 ENSMUST00000141560.1
transmembrane BAX inhibitor motif containing 1
chr7_-_101581161 0.33 ENSMUST00000063920.2
ADP-ribosyltransferase 2b
chr11_-_102365111 0.32 ENSMUST00000006749.9
solute carrier family 4 (anion exchanger), member 1
chr8_+_114439655 0.32 ENSMUST00000004756.7
ENSMUST00000109108.2
ENSMUST00000160862.1
ENSMUST00000109107.2
WW domain-containing oxidoreductase
chr11_+_120232921 0.32 ENSMUST00000122148.1
ENSMUST00000044985.7
BAH domain and coiled-coil containing 1
chr18_+_42511496 0.32 ENSMUST00000025375.7
transcription elongation regulator 1 (CA150)
chr5_-_108434373 0.32 ENSMUST00000049628.9
ENSMUST00000118632.1
ATP synthase, H+ transporting, mitochondrial F1F0 complex, subunit e
chrX_+_164373363 0.32 ENSMUST00000033751.7
c-fos induced growth factor
chr9_-_26999491 0.30 ENSMUST00000060513.7
ENSMUST00000120367.1
acyl-Coenzyme A dehydrogenase family, member 8
chr13_-_62607499 0.30 ENSMUST00000091563.4
RIKEN cDNA 6720489N17 gene
chr2_+_157737401 0.30 ENSMUST00000029178.6
catenin, beta like 1
chr14_+_47298260 0.30 ENSMUST00000166743.1
mitogen-activated protein kinase 1 interacting protein 1-like
chr7_-_28949670 0.29 ENSMUST00000148196.1
actinin alpha 4
chr7_+_28788955 0.29 ENSMUST00000059857.7
Ras and Rab interactor-like
chrX_+_56913421 0.29 ENSMUST00000168724.1
G protein-coupled receptor 112
chr11_-_101417615 0.28 ENSMUST00000070395.8
alanyl-tRNA synthetase domain containing 1
chr16_-_44332925 0.26 ENSMUST00000136381.1
SID1 transmembrane family, member 1
chr18_-_36454487 0.26 ENSMUST00000025204.5
prefoldin 1
chr8_+_94525067 0.25 ENSMUST00000098489.4
NLR family, CARD domain containing 5
chr16_+_57353093 0.25 ENSMUST00000159816.1
filamin A interacting protein 1-like
chr1_+_42697146 0.25 ENSMUST00000054883.2
POU domain, class 3, transcription factor 3
chr13_+_49544443 0.25 ENSMUST00000177948.1
ENSMUST00000021820.6
asporin
chr15_-_85811644 0.24 ENSMUST00000144067.1
ENSMUST00000134631.1
ENSMUST00000154814.1
ENSMUST00000071876.6
ENSMUST00000150995.1
cysteine rich, DPF motif domain containing 1
chr3_-_126998408 0.24 ENSMUST00000182764.1
ENSMUST00000044443.8
ankyrin 2, brain
chr2_+_163602331 0.23 ENSMUST00000152135.1
tocopherol (alpha) transfer protein-like
chr11_+_105994635 0.23 ENSMUST00000183675.1
ENSMUST00000184871.1
angiotensin I converting enzyme 3 precursor
angiotensin I converting enzyme (peptidyl-dipeptidase A) 3
chr17_-_34603675 0.23 ENSMUST00000015622.7
ring finger protein 5
chr14_+_3847027 0.23 ENSMUST00000112792.3
predicted gene 3033
chr15_-_76918010 0.23 ENSMUST00000048854.7
zinc finger protein 647
chr10_-_116549101 0.22 ENSMUST00000164088.1
CCR4-NOT transcription complex, subunit 2
chr11_-_69920581 0.22 ENSMUST00000108610.1
eukaryotic translation initiation factor 5A
chr16_+_43235856 0.22 ENSMUST00000146708.1
zinc finger and BTB domain containing 20
chr14_-_55713482 0.22 ENSMUST00000168729.1
ENSMUST00000178034.1
transglutaminase 1, K polypeptide
chr14_+_74732297 0.21 ENSMUST00000022573.10
ENSMUST00000175712.1
esterase D/formylglutathione hydrolase
chr1_-_161979636 0.21 ENSMUST00000162676.1
RIKEN cDNA 4930558K02 gene
chr5_+_32247351 0.21 ENSMUST00000101376.2
phospholipase B1
chrX_-_7188713 0.21 ENSMUST00000004428.7
chloride channel 5
chr8_-_106337987 0.20 ENSMUST00000067512.7
sphingomyelin phosphodiesterase 3, neutral
chr14_+_74732384 0.19 ENSMUST00000176957.1
esterase D/formylglutathione hydrolase
chr1_-_74304386 0.19 ENSMUST00000016309.9
transmembrane BAX inhibitor motif containing 1
chr16_+_32400506 0.19 ENSMUST00000115149.2
transmembrane 4 L six family member 19
chr1_-_74304345 0.18 ENSMUST00000113796.1
transmembrane BAX inhibitor motif containing 1
chr11_-_103938211 0.18 ENSMUST00000133774.2
ENSMUST00000149642.1
N-ethylmaleimide sensitive fusion protein
chr15_+_51877742 0.18 ENSMUST00000136129.1
UTP23, small subunit (SSU) processome component, homolog (yeast)
chr18_+_34759551 0.17 ENSMUST00000097622.3
family with sequence similarity 53, member C
chr11_+_66956620 0.16 ENSMUST00000150220.1
RIKEN cDNA 9130409J20 gene
chr17_+_46772635 0.16 ENSMUST00000071430.5
RIKEN cDNA 2310039H08 gene
chr6_+_147032528 0.16 ENSMUST00000036194.4
RAB15 effector protein
chr10_+_94147982 0.15 ENSMUST00000105290.2
nuclear receptor subfamily 2, group C, member 1
chr1_+_170277376 0.15 ENSMUST00000179976.1
SH2 domain protein 1B1
chr10_+_69706326 0.15 ENSMUST00000182992.1
ankyrin 3, epithelial
chr8_+_94838321 0.15 ENSMUST00000034234.8
ENSMUST00000159871.1
coenzyme Q9 homolog (yeast)
chr13_+_63282142 0.14 ENSMUST00000159152.1
RIKEN cDNA 2010111I01 gene
chr10_+_76562270 0.13 ENSMUST00000009259.4
ENSMUST00000105414.1
spermatogenesis and centriole associated 1 like
chr10_-_70655934 0.13 ENSMUST00000162144.1
ENSMUST00000162793.1
phytanoyl-CoA hydroxylase interacting protein-like
chr3_-_98457031 0.13 ENSMUST00000167753.1
predicted gene 4450
chr3_-_98509967 0.13 ENSMUST00000179429.1
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 4
chr2_-_163397946 0.13 ENSMUST00000017961.4
ENSMUST00000109425.2
junctophilin 2
chr10_+_56106883 0.13 ENSMUST00000063138.7
male-specific lethal 3-like 2 (Drosophila)
chr6_-_148831448 0.12 ENSMUST00000048418.7
importin 8
chr11_+_58954675 0.12 ENSMUST00000108817.3
ENSMUST00000047697.5
histone cluster 3, H2a
tripartite motif-containing 17
chr11_+_58778089 0.11 ENSMUST00000081533.2
olfactory receptor 315
chr6_+_115944936 0.10 ENSMUST00000037831.7
ENSMUST00000161617.1
ENSMUST00000161969.1
H1 histone family, member O, oocyte-specific
chr9_+_86743616 0.10 ENSMUST00000036426.6
protease, serine, 35
chrX_+_107148927 0.10 ENSMUST00000147521.1
ENSMUST00000167673.1
RIKEN cDNA A630033H20 gene
chr6_-_48708206 0.10 ENSMUST00000119315.1
ENSMUST00000053661.4
GTPase, IMAP family member 6
chr11_-_72550255 0.10 ENSMUST00000021154.6
spinster homolog 3
chr19_-_11856001 0.09 ENSMUST00000079875.3
olfactory receptor 1418
chr4_-_108301045 0.08 ENSMUST00000043616.6
zyg-ll family member B, cell cycle regulator
chr13_+_21180179 0.08 ENSMUST00000021761.5
tripartite motif-containing 27
chrX_-_75380041 0.07 ENSMUST00000114085.2
coagulation factor VIII
chr11_+_53433299 0.07 ENSMUST00000018382.6
growth differentiation factor 9
chr3_-_98564038 0.07 ENSMUST00000058728.5
predicted gene 10681
chr14_-_6874257 0.06 ENSMUST00000179374.1
ENSMUST00000178298.1
predicted gene 3629
predicted gene 3667
chr9_+_86743641 0.06 ENSMUST00000179574.1
protease, serine, 35
chr9_+_108662098 0.06 ENSMUST00000035222.5
solute carrier family 25 (mitochondrial carnitine/acylcarnitine translocase), member 20
chr8_+_8689666 0.05 ENSMUST00000179702.1
RIKEN cDNA B930078G14 gene
chr10_-_92164666 0.05 ENSMUST00000183123.1
ENSMUST00000182033.1
rhabdomyosarcoma 2 associated transcript (non-coding RNA)
chr15_+_51877429 0.05 ENSMUST00000137116.2
ENSMUST00000161651.1
ENSMUST00000059599.9
UTP23, small subunit (SSU) processome component, homolog (yeast)
chr8_+_25601591 0.05 ENSMUST00000155861.1
Wolf-Hirschhorn syndrome candidate 1-like 1 (human)
chr1_+_165763746 0.04 ENSMUST00000111432.3
cellular repressor of E1A-stimulated genes 1
chr4_+_42714926 0.04 ENSMUST00000178454.1
predicted gene, 21955
chr2_+_150190393 0.02 ENSMUST00000109929.2
predicted gene 14139
chr5_-_66618636 0.01 ENSMUST00000162382.1
ENSMUST00000160870.1
ENSMUST00000087256.5
ENSMUST00000160103.1
ENSMUST00000162349.1
amyloid beta (A4) precursor protein-binding, family B, member 2
chr9_-_60649793 0.01 ENSMUST00000053171.7
leucine rich repeat containing 49
chr2_+_137663424 0.01 ENSMUST00000134833.1
predicted gene 14064
chr5_-_35729276 0.01 ENSMUST00000070203.7
SH3 domain and tetratricopeptide repeats 1
chr2_+_57997884 0.01 ENSMUST00000112616.1
ENSMUST00000166729.1
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5
chr8_-_95294074 0.01 ENSMUST00000184103.1
cyclic nucleotide gated channel beta 1
chr12_+_108410625 0.00 ENSMUST00000109857.1
echinoderm microtubule associated protein like 1
chr9_-_49798905 0.00 ENSMUST00000114476.2
neural cell adhesion molecule 1
chr7_+_4925802 0.00 ENSMUST00000057612.7
scavenger receptor cysteine rich domain containing (5 domains)

Network of associatons between targets according to the STRING database.

First level regulatory network of Neurog2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.9 GO:0032796 uropod organization(GO:0032796)
0.5 1.4 GO:1904975 response to bleomycin(GO:1904975) cellular response to bleomycin(GO:1904976)
0.4 1.6 GO:0002143 tRNA wobble position uridine thiolation(GO:0002143)
0.3 1.3 GO:0060857 establishment of glial blood-brain barrier(GO:0060857)
0.3 1.0 GO:0042851 L-alanine metabolic process(GO:0042851)
0.3 0.9 GO:0034334 adherens junction maintenance(GO:0034334)
0.2 2.0 GO:2000298 regulation of Rho-dependent protein serine/threonine kinase activity(GO:2000298)
0.2 0.7 GO:2000328 regulation of T-helper 17 cell lineage commitment(GO:2000328)
0.2 1.4 GO:0003431 growth plate cartilage chondrocyte development(GO:0003431)
0.2 1.2 GO:0072717 cellular response to actinomycin D(GO:0072717)
0.2 2.3 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.2 1.1 GO:0006177 GMP biosynthetic process(GO:0006177)
0.2 0.9 GO:0042822 pyridoxal phosphate metabolic process(GO:0042822)
0.2 0.5 GO:0002362 CD4-positive, CD25-positive, alpha-beta regulatory T cell lineage commitment(GO:0002362) negative regulation of histone deacetylation(GO:0031064) positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032831) negative regulation of interferon-gamma biosynthetic process(GO:0045077)
0.2 0.7 GO:1902045 regulation of Fas signaling pathway(GO:1902044) negative regulation of Fas signaling pathway(GO:1902045)
0.2 0.5 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.2 0.5 GO:0006404 RNA import into nucleus(GO:0006404) mRNA export from nucleus in response to heat stress(GO:0031990) negative regulation of nucleobase-containing compound transport(GO:0032240) negative regulation of RNA export from nucleus(GO:0046832)
0.2 1.9 GO:2001269 positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269)
0.2 0.5 GO:0070904 L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904)
0.1 0.4 GO:1900864 mitochondrial tRNA modification(GO:0070900) mitochondrial RNA modification(GO:1900864)
0.1 0.6 GO:0006545 glycine biosynthetic process(GO:0006545)
0.1 0.8 GO:0045905 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.1 0.6 GO:0060278 regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.1 2.6 GO:0006978 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978)
0.1 0.9 GO:0048539 bone marrow development(GO:0048539) replicative senescence(GO:0090399)
0.1 0.4 GO:0046294 formaldehyde catabolic process(GO:0046294)
0.1 0.3 GO:1902396 protein localization to bicellular tight junction(GO:1902396)
0.1 0.3 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.1 0.8 GO:0033227 dsRNA transport(GO:0033227)
0.1 0.3 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.1 0.8 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.1 2.8 GO:0044062 regulation of excretion(GO:0044062)
0.1 0.4 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
0.1 3.6 GO:0043029 T cell homeostasis(GO:0043029)
0.1 0.3 GO:0019364 pyridine nucleotide catabolic process(GO:0019364)
0.1 0.3 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.1 0.2 GO:0072235 distal convoluted tubule development(GO:0072025) metanephric distal convoluted tubule development(GO:0072221) metanephric distal tubule development(GO:0072235)
0.1 0.5 GO:0003356 regulation of cilium movement(GO:0003352) regulation of cilium beat frequency(GO:0003356)
0.1 0.5 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.1 0.9 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.2 GO:0070171 negative regulation of tooth mineralization(GO:0070171)
0.0 0.7 GO:0031272 regulation of pseudopodium assembly(GO:0031272)
0.0 0.2 GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.0 0.9 GO:0031340 positive regulation of vesicle fusion(GO:0031340)
0.0 0.4 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000) very long-chain fatty acid catabolic process(GO:0042760)
0.0 0.5 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.5 GO:0033623 regulation of integrin activation(GO:0033623)
0.0 0.1 GO:0002767 immune response-inhibiting cell surface receptor signaling pathway(GO:0002767)
0.0 1.1 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.2 GO:0090154 positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.0 0.3 GO:0045345 MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343) positive regulation of MHC class I biosynthetic process(GO:0045345)
0.0 0.3 GO:2001241 positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241)
0.0 1.4 GO:0030490 maturation of SSU-rRNA(GO:0030490)
0.0 0.2 GO:0036371 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.0 0.1 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.0 0.4 GO:0015812 gamma-aminobutyric acid secretion(GO:0014051) gamma-aminobutyric acid transport(GO:0015812)
0.0 0.1 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
0.0 0.2 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0 0.3 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 0.4 GO:0090344 negative regulation of cell aging(GO:0090344)
0.0 0.2 GO:2000344 positive regulation of acrosome reaction(GO:2000344)
0.0 0.9 GO:0010972 negative regulation of G2/M transition of mitotic cell cycle(GO:0010972)
0.0 0.1 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376)
0.0 0.3 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.0 0.1 GO:2000870 regulation of progesterone secretion(GO:2000870)
0.0 0.4 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 1.3 GO:0033045 regulation of sister chromatid segregation(GO:0033045)
0.0 0.1 GO:0048386 positive regulation of retinoic acid receptor signaling pathway(GO:0048386)
0.0 0.2 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.0 0.3 GO:0014823 response to activity(GO:0014823)
0.0 0.1 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.0 0.4 GO:0050869 negative regulation of B cell activation(GO:0050869)
0.0 0.4 GO:0071539 protein localization to centrosome(GO:0071539)
0.0 0.1 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.2 GO:0031424 keratinization(GO:0031424)
0.0 0.1 GO:0015879 carnitine transport(GO:0015879)
0.0 0.2 GO:0033572 transferrin transport(GO:0033572)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0034457 Mpp10 complex(GO:0034457)
0.2 0.6 GO:0043512 inhibin A complex(GO:0043512)
0.2 2.8 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.1 0.6 GO:0070552 BRISC complex(GO:0070552)
0.1 2.9 GO:0032426 stereocilium tip(GO:0032426)
0.1 0.8 GO:0045261 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.1 0.9 GO:0000782 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.1 0.5 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.1 0.8 GO:0005642 annulate lamellae(GO:0005642)
0.1 0.5 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.1 1.0 GO:0031143 pseudopodium(GO:0031143)
0.1 1.1 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.1 0.6 GO:0000243 commitment complex(GO:0000243)
0.1 0.9 GO:0070938 contractile ring(GO:0070938)
0.0 0.7 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.4 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.0 2.3 GO:0015030 Cajal body(GO:0015030)
0.0 0.3 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 0.2 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 0.1 GO:0001674 female germ cell nucleus(GO:0001674)
0.0 0.3 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.5 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 0.5 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 2.0 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 0.3 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 1.1 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.3 GO:0000974 Prp19 complex(GO:0000974)
0.0 2.6 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.6 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.2 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 1.9 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.1 GO:0030314 junctional membrane complex(GO:0030314)
0.0 0.9 GO:0031201 SNARE complex(GO:0031201)
0.0 1.2 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.2 GO:0036513 Derlin-1 retrotranslocation complex(GO:0036513)
0.0 0.3 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 1.2 GO:0014704 intercalated disc(GO:0014704)
0.0 0.5 GO:0097546 ciliary base(GO:0097546)
0.0 1.4 GO:0005814 centriole(GO:0005814)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.9 GO:0050429 calcium-dependent phospholipase C activity(GO:0050429)
0.3 1.1 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.2 0.9 GO:0033883 pyridoxal phosphatase activity(GO:0033883)
0.2 1.9 GO:0008494 translation activator activity(GO:0008494)
0.2 0.6 GO:0004793 threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.2 3.4 GO:0032036 myosin heavy chain binding(GO:0032036)
0.2 0.5 GO:0008520 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.1 0.7 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.1 1.2 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.1 4.7 GO:0051393 alpha-actinin binding(GO:0051393)
0.1 0.8 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.1 0.4 GO:0018738 S-formylglutathione hydrolase activity(GO:0018738)
0.1 0.9 GO:0048101 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1 1.6 GO:0016783 sulfurtransferase activity(GO:0016783)
0.1 0.3 GO:0045352 interleukin-1, Type II receptor binding(GO:0005151) interleukin-1 receptor antagonist activity(GO:0005152) interleukin-1 Type I receptor antagonist activity(GO:0045352) interleukin-1 Type II receptor antagonist activity(GO:0045353)
0.1 0.3 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.1 0.3 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.1 0.6 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 1.1 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.1 0.2 GO:0050253 retinyl-palmitate esterase activity(GO:0050253)
0.1 0.9 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.1 0.4 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.0 0.8 GO:0017070 U6 snRNA binding(GO:0017070)
0.0 0.9 GO:0019215 intermediate filament binding(GO:0019215)
0.0 0.8 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.5 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.5 GO:0000339 RNA cap binding(GO:0000339)
0.0 1.0 GO:0008483 transaminase activity(GO:0008483)
0.0 0.7 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.2 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.0 0.2 GO:0001226 RNA polymerase II transcription corepressor binding(GO:0001226)
0.0 0.4 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.7 GO:0005123 death receptor binding(GO:0005123)
0.0 0.2 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.2 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.8 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.1 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.0 0.3 GO:0003956 NAD(P)+-protein-arginine ADP-ribosyltransferase activity(GO:0003956)
0.0 0.5 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.4 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.4 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.2 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 1.0 GO:0044390 ubiquitin-like protein conjugating enzyme binding(GO:0044390)
0.0 0.6 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.6 GO:0017069 snRNA binding(GO:0017069)
0.0 0.3 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.5 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.3 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.0 0.5 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487) dynein complex binding(GO:0070840)
0.0 0.1 GO:0015226 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.0 0.9 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.2 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.0 0.1 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0 0.2 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.3 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.7 GO:0001540 beta-amyloid binding(GO:0001540)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.4 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.1 3.6 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 2.8 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 0.3 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 1.2 PID P53 REGULATION PATHWAY p53 pathway
0.0 0.7 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 0.5 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.6 PID ALK1 PATHWAY ALK1 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.6 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.1 3.1 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.1 1.1 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.1 1.1 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.1 0.6 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.8 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.4 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 1.0 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 1.4 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS Genes involved in CREB phosphorylation through the activation of Ras
0.0 0.3 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.9 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.8 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.0 0.4 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.5 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.0 0.5 REACTOME ENOS ACTIVATION AND REGULATION Genes involved in eNOS activation and regulation
0.0 0.7 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.4 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.5 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.5 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.0 0.3 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.2 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 1.7 REACTOME 3 UTR MEDIATED TRANSLATIONAL REGULATION Genes involved in 3' -UTR-mediated translational regulation
0.0 0.2 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors