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2D miR_HR1_12

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Results for Klf13

Z-value: 1.49

Motif logo

Transcription factors associated with Klf13

Gene Symbol Gene ID Gene Info
ENSMUSG00000052040.9 Kruppel-like factor 13

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Klf13mm10_v2_chr7_-_63938862_63938933-0.913.2e-05Click!

Activity profile of Klf13 motif

Sorted Z-values of Klf13 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr11_+_69964758 5.74 ENSMUST00000108597.1
ENSMUST00000060651.5
ENSMUST00000108596.1
claudin 7
chr11_+_69965396 5.02 ENSMUST00000018713.6
claudin 7
chr4_-_117133953 2.74 ENSMUST00000076859.5
polo-like kinase 3
chr13_-_49215978 2.61 ENSMUST00000048946.6
RIKEN cDNA 1110007C09 gene
chr11_+_101665541 2.39 ENSMUST00000039388.2
ADP-ribosylation factor-like 4D
chr11_+_67025144 2.28 ENSMUST00000079077.5
ENSMUST00000061786.5
transmembrane protein 220
chr7_+_80246529 2.03 ENSMUST00000107381.1
tubulin tyrosine ligase-like family, member 13
chr17_-_35909626 1.83 ENSMUST00000141132.1
alpha tubulin acetyltransferase 1
chr5_-_115158169 1.81 ENSMUST00000053271.5
ENSMUST00000112121.1
malectin
chr5_+_35757875 1.80 ENSMUST00000101280.3
ENSMUST00000054598.5
ENSMUST00000114205.1
ENSMUST00000114206.2
actin-binding LIM protein 2
chr4_-_43040279 1.73 ENSMUST00000107958.1
ENSMUST00000107959.1
ENSMUST00000152846.1
family with sequence similarity 214, member B
chr7_+_80246375 1.72 ENSMUST00000058266.6
tubulin tyrosine ligase-like family, member 13
chr4_+_136143497 1.68 ENSMUST00000008016.2
inhibitor of DNA binding 3
chr17_-_35910032 1.49 ENSMUST00000141662.1
ENSMUST00000056034.6
ENSMUST00000077494.6
ENSMUST00000149277.1
ENSMUST00000061052.5
alpha tubulin acetyltransferase 1
chr12_+_108334341 1.40 ENSMUST00000021684.4
cytochrome P450, family 46, subfamily a, polypeptide 1
chr9_+_75410145 1.35 ENSMUST00000180533.1
ENSMUST00000180574.1
RIKEN cDNA 4933433G15 gene
chr17_-_87282771 1.33 ENSMUST00000161759.1
RIKEN cDNA 4833418N02 gene
chr11_-_119040905 1.27 ENSMUST00000026663.7
chromobox 8
chr11_+_116532441 1.26 ENSMUST00000106386.1
ENSMUST00000145737.1
ENSMUST00000155102.1
ENSMUST00000063446.6
sphingosine kinase 1
chr5_+_35757951 1.24 ENSMUST00000114204.1
ENSMUST00000129347.1
actin-binding LIM protein 2
chr4_-_142015056 1.20 ENSMUST00000105780.1
forkhead-associated (FHA) phosphopeptide binding domain 1
chr7_-_27178835 1.16 ENSMUST00000093040.6
RAB4B, member RAS oncogene family
chr6_+_83794974 1.13 ENSMUST00000037376.7
N-acetylglucosamine kinase
chr7_-_16874845 1.12 ENSMUST00000181501.1
RIKEN cDNA 9330104G04 gene
chr10_-_62340514 1.12 ENSMUST00000099691.4
hexokinase 1
chr9_-_18473559 1.05 ENSMUST00000034647.4
zinc finger protein 558
chr6_+_83795205 1.04 ENSMUST00000113850.1
N-acetylglucosamine kinase
chr4_-_150008977 1.03 ENSMUST00000030830.3
hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
chr17_-_87282793 1.02 ENSMUST00000146560.2
RIKEN cDNA 4833418N02 gene
chr14_+_122107038 1.02 ENSMUST00000026624.4
transmembrane 9 superfamily member 2
chr12_-_79172609 1.02 ENSMUST00000055262.6
vesicle transport through interaction with t-SNAREs 1B
chr5_+_135689036 0.97 ENSMUST00000005651.6
ENSMUST00000122113.1
P450 (cytochrome) oxidoreductase
chr8_-_94876269 0.96 ENSMUST00000046461.7
docking protein 4
chr3_+_106721893 0.95 ENSMUST00000106736.2
ENSMUST00000154973.1
ENSMUST00000131330.1
ENSMUST00000150513.1
ligand dependent nuclear receptor interacting factor 1
chr3_+_106721672 0.95 ENSMUST00000098750.2
ENSMUST00000130105.1
ligand dependent nuclear receptor interacting factor 1
chr6_+_83795022 0.94 ENSMUST00000113851.1
N-acetylglucosamine kinase
chr14_-_47189406 0.93 ENSMUST00000089959.6
GTP cyclohydrolase 1
chr14_+_122107119 0.92 ENSMUST00000171318.1
transmembrane 9 superfamily member 2
chr8_-_71558871 0.92 ENSMUST00000052072.6
transmembrane protein 221
chr11_-_76399107 0.84 ENSMUST00000021204.3
nucleoredoxin
chr2_-_170131156 0.83 ENSMUST00000063710.6
zinc finger protein 217
chr2_+_32288244 0.82 ENSMUST00000113377.1
ENSMUST00000100194.2
golgi autoantigen, golgin subfamily a, 2
chr9_+_88581036 0.80 ENSMUST00000164661.2
tripartite motif-containing 43A
chr3_+_61002786 0.78 ENSMUST00000029331.1
purinergic receptor P2Y, G-protein coupled 1
chr7_-_30563184 0.77 ENSMUST00000043898.6
presenilin enhancer 2 homolog (C. elegans)
chr7_+_19181159 0.76 ENSMUST00000120595.1
ENSMUST00000048502.8
echinoderm microtubule associated protein like 2
chr2_+_167538192 0.75 ENSMUST00000052631.7
snail homolog 1 (Drosophila)
chr2_+_120977017 0.72 ENSMUST00000067582.7
transmembrane protein 62
chr10_-_127211528 0.69 ENSMUST00000013970.7
phosphatidylinositol-5-phosphate 4-kinase, type II, gamma
chr1_-_161876656 0.68 ENSMUST00000048377.5
SUN domain containing ossification factor
chr7_+_5020376 0.66 ENSMUST00000076251.4
zinc finger protein 865
chr2_-_26445175 0.62 ENSMUST00000114082.2
ENSMUST00000091252.4
SEC16 homolog A (S. cerevisiae)
chr1_-_36445248 0.60 ENSMUST00000125304.1
ENSMUST00000115011.1
lectin, mannose-binding 2-like
chr5_-_38220400 0.60 ENSMUST00000114113.1
ENSMUST00000094833.3
zinc finger and BTB domain containing 49
chr4_+_140906344 0.56 ENSMUST00000030765.6
peptidyl arginine deiminase, type II
chr19_+_56722372 0.56 ENSMUST00000038949.4
adrenergic receptor, beta 1
chr1_+_128244122 0.54 ENSMUST00000027592.3
UBX domain protein 4
chrX_-_150813637 0.53 ENSMUST00000112700.1
melanoma antigen, family D, 2
chr16_+_4726357 0.51 ENSMUST00000154117.1
ENSMUST00000004172.8
heme oxygenase (decycling) 2
chr7_+_5020561 0.50 ENSMUST00000085427.3
zinc finger protein 865
chr14_-_118706180 0.48 ENSMUST00000036554.6
ENSMUST00000166646.1
ATP-binding cassette, sub-family C (CFTR/MRP), member 4
chr19_+_46761578 0.48 ENSMUST00000077666.4
ENSMUST00000099373.4
cyclin M2
chr10_-_40257648 0.48 ENSMUST00000019982.7
general transcription factor IIIC, polypeptide 6, alpha
chr3_+_145924303 0.48 ENSMUST00000029842.7
B cell leukemia/lymphoma 10
chr2_-_24935054 0.47 ENSMUST00000132074.1
arrestin domain containing 1
chr19_+_44931119 0.45 ENSMUST00000096053.3
family with sequence similarity 178, member A
chr11_-_59787636 0.45 ENSMUST00000125307.1
phospholipase D family, member 6
chr18_-_46597299 0.45 ENSMUST00000036030.7
transmembrane emp24 protein transport domain containing 7
chr9_-_75409951 0.45 ENSMUST00000049355.10
mitogen-activated protein kinase 6
chr7_-_16614937 0.45 ENSMUST00000171937.1
ENSMUST00000075845.4
glucocorticoid receptor DNA binding factor 1
chr18_-_46597480 0.45 ENSMUST00000151189.1
transmembrane emp24 protein transport domain containing 7
chr9_-_31211805 0.44 ENSMUST00000072634.7
ENSMUST00000079758.7
amyloid beta (A4) precursor-like protein 2
chr5_-_137741601 0.44 ENSMUST00000119498.1
ENSMUST00000061789.7
neuronal tyrosine-phosphorylated phosphoinositide 3-kinase adaptor 1
chr8_+_84949860 0.43 ENSMUST00000121880.1
retbindin
chr5_-_138264013 0.43 ENSMUST00000161604.1
ENSMUST00000163268.1
cDNA sequence BC037034
cDNA sequence BC037034
chr5_-_139736291 0.42 ENSMUST00000044642.10
MICAL-like 2
chr19_-_5610038 0.39 ENSMUST00000113641.2
K(lysine) acetyltransferase 5
chr10_-_44458715 0.38 ENSMUST00000039174.4
PR domain containing 1, with ZNF domain
chr5_-_138263942 0.38 ENSMUST00000048421.7
ENSMUST00000164203.1
cDNA sequence BC037034
cDNA sequence BC037034
chr4_-_119422355 0.37 ENSMUST00000106316.1
ENSMUST00000030385.6
phosphopantothenoylcysteine synthetase
chr2_-_73892619 0.36 ENSMUST00000112007.1
ENSMUST00000112016.2
activating transcription factor 2
chr2_-_73892588 0.35 ENSMUST00000154456.1
ENSMUST00000090802.4
ENSMUST00000055833.5
activating transcription factor 2
chr4_-_116807574 0.33 ENSMUST00000030451.3
target of EGR1, member 1 (nuclear)
chr6_-_82652856 0.33 ENSMUST00000160281.1
ENSMUST00000095786.5
polymerase (DNA-directed), epsilon 4 (p12 subunit)
chr12_+_102469123 0.32 ENSMUST00000179218.1
golgi autoantigen, golgin subfamily a, 5
chr9_+_57697612 0.29 ENSMUST00000034865.4
cytochrome P450, family 1, subfamily a, polypeptide 1
chr17_+_56717759 0.28 ENSMUST00000002452.6
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 11
chr17_+_34564268 0.27 ENSMUST00000015612.7
notch 4
chr18_+_67343564 0.26 ENSMUST00000025404.8
cell death-inducing DNA fragmentation factor, alpha subunit-like effector A
chr9_-_78587968 0.26 ENSMUST00000117645.1
ENSMUST00000119213.1
ENSMUST00000052441.5
solute carrier family 17 (anion/sugar transporter), member 5
chr8_+_83608175 0.25 ENSMUST00000005620.8
DnaJ (Hsp40) homolog, subfamily B, member 1
chr2_-_73892530 0.24 ENSMUST00000136958.1
ENSMUST00000112010.2
ENSMUST00000128531.1
ENSMUST00000112017.1
activating transcription factor 2
chr5_-_137502402 0.24 ENSMUST00000111035.1
ENSMUST00000031728.4
processing of precursor 7, ribonuclease P family, (S. cerevisiae)
chr12_-_14152038 0.23 ENSMUST00000020926.6
family with sequence similarity 84, member A
chr7_-_144582392 0.22 ENSMUST00000033394.7
Fas (TNFRSF6)-associated via death domain
chr2_-_35200923 0.22 ENSMUST00000028238.8
ENSMUST00000113025.1
RAB14, member RAS oncogene family
chr16_+_22920222 0.21 ENSMUST00000023587.4
ENSMUST00000116625.2
fetuin beta
chr8_+_3631109 0.20 ENSMUST00000004745.8
syntaxin binding protein 2
chr4_-_116807532 0.19 ENSMUST00000106455.1
target of EGR1, member 1 (nuclear)
chr7_-_122021143 0.19 ENSMUST00000033160.8
golgi associated, gamma adaptin ear containing, ARF binding protein 2
chr5_-_137741102 0.18 ENSMUST00000149512.1
neuronal tyrosine-phosphorylated phosphoinositide 3-kinase adaptor 1
chr2_-_24935148 0.17 ENSMUST00000102935.3
ENSMUST00000133934.1
ENSMUST00000028349.7
arrestin domain containing 1
chr1_-_74600564 0.17 ENSMUST00000127938.1
ENSMUST00000154874.1
ring finger protein 25
chr7_+_25619404 0.15 ENSMUST00000077338.5
ENSMUST00000085953.3
ATP5S-like
chr8_+_69832633 0.14 ENSMUST00000131637.2
ENSMUST00000081503.6
pre B cell leukemia homeobox 4
chr1_+_164796723 0.14 ENSMUST00000027861.4
dermatopontin
chr15_-_64922290 0.13 ENSMUST00000023007.5
adenylate cyclase 8
chr8_-_36249292 0.12 ENSMUST00000065297.5
LON peptidase N-terminal domain and ring finger 1
chr4_-_135272798 0.11 ENSMUST00000037099.8
chloride intracellular channel 4 (mitochondrial)
chr14_+_54426902 0.10 ENSMUST00000010550.7
mitochondrial ribosomal protein L52
chr7_+_30563298 0.08 ENSMUST00000043273.9
ENSMUST00000163654.1
ENSMUST00000166510.1
ENSMUST00000163482.1
ENSMUST00000166257.1
ENSMUST00000163464.1
ENSMUST00000171850.1
ENSMUST00000168931.1
U2 small nuclear RNA auxiliary factor 1-like 4
chr1_-_195092242 0.08 ENSMUST00000162650.1
ENSMUST00000160817.1
ENSMUST00000162614.1
ENSMUST00000016637.6
CD46 antigen, complement regulatory protein
chr14_-_76010863 0.07 ENSMUST00000088922.4
general transcription factor IIF, polypeptide 2
chr19_-_42129043 0.06 ENSMUST00000018965.3
arginine vasopressin-induced 1
chr8_-_71486037 0.06 ENSMUST00000093450.4
anoctamin 8
chr6_+_71293765 0.03 ENSMUST00000114185.2
predicted gene 1070
chr10_-_24712133 0.02 ENSMUST00000105520.1
ectonucleotide pyrophosphatase/phosphodiesterase 1
chr17_+_87282880 0.01 ENSMUST00000041110.5
ENSMUST00000125875.1
tetratricopeptide repeat domain 7

Network of associatons between targets according to the STRING database.

First level regulatory network of Klf13

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.3 GO:0071929 alpha-tubulin acetylation(GO:0071929)
0.6 10.8 GO:0032463 negative regulation of protein homooligomerization(GO:0032463)
0.4 3.1 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.4 3.6 GO:0090166 Golgi disassembly(GO:0090166)
0.3 0.8 GO:0032962 positive regulation of inositol trisphosphate biosynthetic process(GO:0032962)
0.2 1.0 GO:0043602 nitrate catabolic process(GO:0043602) nitric oxide catabolic process(GO:0046210) cellular organohalogen metabolic process(GO:0090345) cellular organofluorine metabolic process(GO:0090346)
0.2 0.9 GO:0014916 regulation of lung blood pressure(GO:0014916)
0.2 1.3 GO:0019371 cyclooxygenase pathway(GO:0019371)
0.2 0.9 GO:0032915 positive regulation of transforming growth factor beta2 production(GO:0032915)
0.2 0.8 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.2 0.6 GO:0036414 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.2 0.6 GO:1900135 positive regulation of the force of heart contraction by epinephrine-norepinephrine(GO:0001997) positive regulation of the force of heart contraction by chemical signal(GO:0003099) positive regulation of renin secretion into blood stream(GO:1900135)
0.2 1.1 GO:0006735 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.2 0.5 GO:0008358 oocyte construction(GO:0007308) oocyte axis specification(GO:0007309) oocyte anterior/posterior axis specification(GO:0007314) pole plasm assembly(GO:0007315) maternal determination of anterior/posterior axis, embryo(GO:0008358) P granule organization(GO:0030719)
0.1 0.5 GO:0006788 heme oxidation(GO:0006788)
0.1 1.4 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.1 0.8 GO:0010968 regulation of microtubule nucleation(GO:0010968)
0.1 1.0 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.1 0.3 GO:0009804 coumarin metabolic process(GO:0009804) dibenzo-p-dioxin metabolic process(GO:0018894)
0.1 0.5 GO:0002906 mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906)
0.1 0.2 GO:2000451 positive regulation of CD8-positive, alpha-beta T cell extravasation(GO:2000451)
0.1 0.4 GO:0033078 extrathymic T cell differentiation(GO:0033078)
0.1 0.7 GO:2000786 positive regulation of autophagosome assembly(GO:2000786)
0.1 0.5 GO:0070294 renal sodium ion absorption(GO:0070294)
0.1 1.9 GO:0032967 positive regulation of collagen biosynthetic process(GO:0032967)
0.1 1.7 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.1 1.0 GO:0006098 pentose-phosphate shunt(GO:0006098)
0.1 0.8 GO:0007220 Notch receptor processing(GO:0007220)
0.0 0.5 GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.0 0.3 GO:1903847 regulation of aorta morphogenesis(GO:1903847) positive regulation of aorta morphogenesis(GO:1903849)
0.0 0.3 GO:0010890 positive regulation of sequestering of triglyceride(GO:0010890)
0.0 0.5 GO:0032310 prostaglandin secretion(GO:0032310)
0.0 0.3 GO:0090084 negative regulation of inclusion body assembly(GO:0090084)
0.0 0.1 GO:0043380 regulation of memory T cell differentiation(GO:0043380)
0.0 0.3 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0 0.5 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.4 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.4 GO:0071392 cellular response to estradiol stimulus(GO:0071392)
0.0 0.4 GO:0006878 suckling behavior(GO:0001967) cellular copper ion homeostasis(GO:0006878)
0.0 0.2 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.0 0.2 GO:0045176 Golgi to endosome transport(GO:0006895) apical protein localization(GO:0045176)
0.0 0.8 GO:0045454 cell redox homeostasis(GO:0045454)
0.0 0.5 GO:0006383 transcription from RNA polymerase III promoter(GO:0006383)
0.0 0.6 GO:0007029 endoplasmic reticulum organization(GO:0007029)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 10.8 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.4 3.3 GO:0097427 microtubule bundle(GO:0097427)
0.2 0.5 GO:0031088 platelet dense granule membrane(GO:0031088)
0.1 0.4 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.1 1.1 GO:0000137 Golgi cis cisterna(GO:0000137)
0.1 0.8 GO:0070765 gamma-secretase complex(GO:0070765)
0.1 0.4 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.1 1.3 GO:0035102 PRC1 complex(GO:0035102)
0.1 1.2 GO:0032593 insulin-responsive compartment(GO:0032593)
0.1 0.5 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.1 0.3 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.1 0.3 GO:0099522 region of cytosol(GO:0099522) postsynaptic cytosol(GO:0099524)
0.1 0.5 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.0 1.0 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 1.1 GO:0097228 sperm principal piece(GO:0097228)
0.0 0.2 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.0 0.2 GO:0070820 cytolytic granule(GO:0044194) tertiary granule(GO:0070820)
0.0 0.2 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.0 3.0 GO:0005795 Golgi stack(GO:0005795)
0.0 0.6 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.4 GO:0032156 septin cytoskeleton(GO:0032156)
0.0 0.9 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.1 GO:0002079 inner acrosomal membrane(GO:0002079)
0.0 0.1 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.0 0.9 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 1.9 GO:0000784 nuclear chromosome, telomeric region(GO:0000784)
0.0 0.5 GO:0015030 Cajal body(GO:0015030)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 3.1 GO:0045127 N-acetylglucosamine kinase activity(GO:0045127)
0.5 3.3 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.3 1.0 GO:0047936 glucose 1-dehydrogenase [NAD(P)] activity(GO:0047936)
0.3 0.8 GO:0031686 A1 adenosine receptor binding(GO:0031686)
0.2 1.0 GO:0016708 nitric oxide dioxygenase activity(GO:0008941) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor(GO:0016708) iron-cytochrome-c reductase activity(GO:0047726)
0.2 0.7 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.2 0.6 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.2 0.6 GO:0051380 norepinephrine binding(GO:0051380)
0.2 1.3 GO:0017050 sphinganine kinase activity(GO:0008481) D-erythro-sphingosine kinase activity(GO:0017050)
0.2 0.9 GO:0019238 cyclohydrolase activity(GO:0019238)
0.1 0.8 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.1 1.1 GO:0019158 fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.1 0.5 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.1 1.0 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.1 0.8 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.1 1.0 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.1 0.9 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 0.2 GO:0035877 death effector domain binding(GO:0035877)
0.0 0.2 GO:0030348 syntaxin-3 binding(GO:0030348)
0.0 1.7 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.0 0.6 GO:0046030 inositol-polyphosphate 5-phosphatase activity(GO:0004445) inositol trisphosphate phosphatase activity(GO:0046030)
0.0 0.5 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.0 0.5 GO:0015245 fatty acid transporter activity(GO:0015245)
0.0 1.9 GO:0042974 retinoic acid receptor binding(GO:0042974)
0.0 1.7 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.5 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 2.7 GO:0002039 p53 binding(GO:0002039)
0.0 0.4 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.5 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 0.1 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.0 0.2 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 4.1 GO:0016874 ligase activity(GO:0016874)
0.0 0.6 GO:0001223 transcription coactivator binding(GO:0001223)
0.0 0.2 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.4 GO:0031005 filamin binding(GO:0031005)
0.0 9.7 GO:0005198 structural molecule activity(GO:0005198)
0.0 0.8 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.4 GO:0043274 phospholipase binding(GO:0043274)
0.0 0.2 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.3 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.0 0.4 GO:1990841 promoter-specific chromatin binding(GO:1990841)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.3 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 0.8 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 0.5 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.9 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 2.3 PID P73PATHWAY p73 transcription factor network
0.0 1.0 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.8 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 1.1 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 10.8 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.2 1.4 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.1 1.8 REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.1 0.3 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.1 0.8 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.1 0.8 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.1 0.9 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.9 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.4 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 1.3 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 1.1 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.0 0.2 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.6 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.3 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.5 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling
0.0 0.5 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.5 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport