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2D miR_HR1_12

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Results for Epas1_Bcl3

Z-value: 2.38

Motif logo

Transcription factors associated with Epas1_Bcl3

Gene Symbol Gene ID Gene Info
ENSMUSG00000024140.9 endothelial PAS domain protein 1
ENSMUSG00000053175.10 B cell leukemia/lymphoma 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Epas1mm10_v2_chr17_+_86753900_867539140.342.8e-01Click!
Bcl3mm10_v2_chr7_-_19822698_19822776-0.097.9e-01Click!

Activity profile of Epas1_Bcl3 motif

Sorted Z-values of Epas1_Bcl3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_3357012 8.85 ENSMUST00000180719.1
predicted gene, 26520
chr14_-_60177482 6.27 ENSMUST00000140924.1
ATPase, aminophospholipid transporter-like, class I, type 8A, member 2
chr1_-_158958367 5.35 ENSMUST00000159861.2
pappalysin 2
chr6_-_129233969 5.33 ENSMUST00000181517.1
RIKEN cDNA 2310001H17 gene
chr1_-_174921813 4.83 ENSMUST00000055294.3
gremlin 2 homolog, cysteine knot superfamily (Xenopus laevis)
chr13_+_89540636 4.57 ENSMUST00000022108.7
hyaluronan and proteoglycan link protein 1
chr19_+_16956110 4.35 ENSMUST00000087689.4
prune homolog 2 (Drosophila)
chr11_+_34314757 4.12 ENSMUST00000165963.1
ENSMUST00000093192.3
family with sequence similarity 196, member B
chr5_-_134747241 4.11 ENSMUST00000015138.9
elastin
chrX_-_38252398 3.64 ENSMUST00000089056.3
ENSMUST00000089054.4
ENSMUST00000066498.7
transmembrane protein 255A
chr2_+_174760619 3.36 ENSMUST00000029030.2
endothelin 3
chr11_+_61022560 3.24 ENSMUST00000089184.4
potassium inwardly-rectifying channel, subfamily J, member 12
chr4_-_42661893 3.24 ENSMUST00000108006.3
interleukin 11 receptor, alpha chain 2
chr8_+_82863351 3.23 ENSMUST00000078525.5
ring finger protein 150
chr5_+_102481546 3.05 ENSMUST00000112854.1
Rho GTPase activating protein 24
chr2_+_169632996 3.01 ENSMUST00000109159.2
teashirt zinc finger family member 2
chrX_-_162159717 2.95 ENSMUST00000087085.3
Nance-Horan syndrome (human)
chr6_-_112946754 2.84 ENSMUST00000113169.2
SLIT-ROBO Rho GTPase activating protein 3
chr11_+_95010277 2.81 ENSMUST00000124735.1
sterile alpha motif domain containing 14
chr1_+_195017399 2.58 ENSMUST00000181273.1
RIKEN cDNA A330023F24 gene
chr6_+_40628824 2.53 ENSMUST00000071535.6
maltase-glucoamylase
chr7_-_140082489 2.46 ENSMUST00000026541.7
calcyon neuron-specific vesicular protein
chr6_-_129385497 2.44 ENSMUST00000032261.6
C-type lectin domain family 12, member B
chr17_-_28560704 2.44 ENSMUST00000114785.1
ENSMUST00000025062.3
colipase, pancreatic
chr4_+_137862237 2.32 ENSMUST00000102518.3
endothelin converting enzyme 1
chr4_-_132144486 2.26 ENSMUST00000056336.1
opioid receptor, delta 1
chr5_+_35757875 2.25 ENSMUST00000101280.3
ENSMUST00000054598.5
ENSMUST00000114205.1
ENSMUST00000114206.2
actin-binding LIM protein 2
chr1_+_75507077 2.22 ENSMUST00000037330.4
inhibin alpha
chr6_+_145145473 2.16 ENSMUST00000156849.1
ENSMUST00000132948.1
lymphoid-restricted membrane protein
chr13_-_92131494 2.13 ENSMUST00000099326.3
ENSMUST00000146492.1
RAS protein-specific guanine nucleotide-releasing factor 2
chr6_-_112947246 2.07 ENSMUST00000088373.4
SLIT-ROBO Rho GTPase activating protein 3
chr7_+_121392266 2.03 ENSMUST00000084628.3
heparan sulfate (glucosamine) 3-O-sulfotransferase 2
chr1_+_152399824 2.03 ENSMUST00000044311.8
collagen beta(1-O)galactosyltransferase 2
chr6_+_36388055 2.02 ENSMUST00000172278.1
cholinergic receptor, muscarinic 2, cardiac
chr1_-_90969644 1.97 ENSMUST00000130042.1
ENSMUST00000027529.5
RAB17, member RAS oncogene family
chr1_+_120340569 1.94 ENSMUST00000037286.8
complement component 1, q subcomponent-like 2
chr8_+_23153271 1.89 ENSMUST00000071588.6
NK6 homeobox 3
chr7_+_99535652 1.87 ENSMUST00000032995.8
ENSMUST00000162404.1
arrestin, beta 1
chr2_+_106695594 1.83 ENSMUST00000016530.7
metallophosphoesterase domain containing 2
chr9_-_121759788 1.81 ENSMUST00000181325.1
RIKEN cDNA E530011L22 gene
chr7_-_100656953 1.78 ENSMUST00000107046.1
ENSMUST00000107045.1
ENSMUST00000139708.1
pleckstrin homology domain containing, family B (evectins) member 1
chr10_+_102512216 1.77 ENSMUST00000055355.4
Ras association (RalGDS/AF-6) domain family (N-terminal) member 9
chr6_-_124768330 1.76 ENSMUST00000135626.1
enolase 2, gamma neuronal
chr5_-_30461902 1.75 ENSMUST00000133509.1
ENSMUST00000074171.6
ENSMUST00000114747.2
ENSMUST00000144125.1
otoferlin
chr6_+_47244359 1.75 ENSMUST00000060839.6
contactin associated protein-like 2
chr17_-_34882004 1.74 ENSMUST00000152417.1
ENSMUST00000146299.1
complement component 2 (within H-2S)
predicted gene 20547
chr19_+_23758819 1.74 ENSMUST00000025830.7
amyloid beta (A4) precursor protein binding, family A, member 1
chr9_+_66158206 1.72 ENSMUST00000034944.2
death-associated protein kinase 2
chr6_+_71199827 1.71 ENSMUST00000067492.7
fatty acid binding protein 1, liver
chr16_-_52454074 1.70 ENSMUST00000023312.7
activated leukocyte cell adhesion molecule
chr17_-_34882094 1.69 ENSMUST00000025230.8
complement component 2 (within H-2S)
chr5_+_81021202 1.67 ENSMUST00000117253.1
ENSMUST00000120128.1
latrophilin 3
chr6_-_84593810 1.67 ENSMUST00000077705.3
ENSMUST00000168003.2
cytochrome P450, family 26, subfamily b, polypeptide 1
chr5_+_81021583 1.64 ENSMUST00000121707.1
latrophilin 3
chr3_+_105452326 1.62 ENSMUST00000098761.3
potassium voltage-gated channel, Shal-related family, member 3
chr5_-_123141067 1.59 ENSMUST00000162697.1
ENSMUST00000160321.1
ENSMUST00000159637.1
expressed sequence AI480526
chr7_+_99535439 1.57 ENSMUST00000098266.2
ENSMUST00000179755.1
arrestin, beta 1
chr15_+_57694651 1.53 ENSMUST00000096430.4
zinc fingers and homeoboxes 2
chr10_-_5550636 1.52 ENSMUST00000041639.5
spectrin repeat containing, nuclear envelope 1
chr7_-_31054815 1.52 ENSMUST00000071697.4
ENSMUST00000108110.3
FXYD domain-containing ion transport regulator 1
chr8_+_62951361 1.51 ENSMUST00000119068.1
sparc/osteonectin, cwcv and kazal-like domains proteoglycan 3
chr7_-_100863373 1.48 ENSMUST00000142885.1
ENSMUST00000008462.3
RELT tumor necrosis factor receptor
chr3_-_97297778 1.48 ENSMUST00000181368.1
predicted gene, 17608
chr5_+_135168283 1.44 ENSMUST00000031692.5
B cell CLL/lymphoma 7B
chr5_+_64970069 1.43 ENSMUST00000031080.8
family with sequence similarity 114, member A1
chr2_-_172940299 1.41 ENSMUST00000009143.7
bone morphogenetic protein 7
chr12_+_79130777 1.39 ENSMUST00000021550.6
arginase type II
chr17_+_48932368 1.38 ENSMUST00000046254.2
leucine rich repeat and fibronectin type III domain containing 2
chr10_+_17796256 1.38 ENSMUST00000037964.6
taxilin beta
chr9_+_75410145 1.38 ENSMUST00000180533.1
ENSMUST00000180574.1
RIKEN cDNA 4933433G15 gene
chr10_+_127642975 1.38 ENSMUST00000092074.5
ENSMUST00000120279.1
signal transducer and activator of transcription 6
chrX_+_7842056 1.36 ENSMUST00000115667.3
ENSMUST00000115668.3
ENSMUST00000115665.1
OTU domain containing 5
chr11_+_114851814 1.34 ENSMUST00000053361.5
ENSMUST00000021071.7
ENSMUST00000136785.1
G protein-coupled receptor, family C, group 5, member C
chr2_+_119351222 1.33 ENSMUST00000028780.3
ChaC, cation transport regulator 1
chr6_+_124493101 1.32 ENSMUST00000049124.9
complement component 1, r subcomponent-like
chrX_+_53607987 1.31 ENSMUST00000063384.3
ENSMUST00000169626.1
CAAX box 1C
chr11_-_69695521 1.29 ENSMUST00000181261.1
tumor necrosis factor (ligand) superfamily, member 12
chr10_+_42860348 1.27 ENSMUST00000063063.7
sex comb on midleg-like 4 (Drosophila)
chr5_-_123140135 1.27 ENSMUST00000160099.1
expressed sequence AI480526
chr11_+_95009852 1.24 ENSMUST00000055947.3
sterile alpha motif domain containing 14
chr4_-_126325672 1.23 ENSMUST00000102616.1
tektin 2
chr15_-_3583191 1.23 ENSMUST00000069451.4
growth hormone receptor
chr11_+_98348404 1.20 ENSMUST00000078694.6
protein phosphatase 1, regulatory (inhibitor) subunit 1B
chrX_+_53607918 1.19 ENSMUST00000114827.1
CAAX box 1C
chr5_+_135168382 1.19 ENSMUST00000111187.3
ENSMUST00000111188.1
B cell CLL/lymphoma 7B
chr17_+_8525434 1.17 ENSMUST00000115722.1
phosphodiesterase 10A
chr5_+_30588078 1.16 ENSMUST00000066295.2
potassium channel, subfamily K, member 3
chr4_-_126325641 1.14 ENSMUST00000131113.1
tektin 2
chr7_-_27446599 1.11 ENSMUST00000011895.7
spectrin beta, non-erythrocytic 4
chr4_-_129239165 1.11 ENSMUST00000097873.3
expressed sequence C77080
chr3_+_134236483 1.11 ENSMUST00000181904.1
ENSMUST00000053048.9
CXXC finger 4
chr5_-_92505518 1.11 ENSMUST00000031377.7
scavenger receptor class B, member 2
chr19_+_5425121 1.11 ENSMUST00000159759.1
expressed sequence AI837181
chr11_+_69095217 1.10 ENSMUST00000101004.2
period circadian clock 1
chr14_-_70630149 1.07 ENSMUST00000022694.9
dematin actin binding protein
chr9_+_103008479 1.07 ENSMUST00000035148.6
solute carrier organic anion transporter family, member 2a1
chr6_+_128399766 1.05 ENSMUST00000001561.5
nuclear receptor interacting protein 2
chr15_-_3583146 1.04 ENSMUST00000110698.2
growth hormone receptor
chr9_+_89909775 1.03 ENSMUST00000034912.4
ENSMUST00000034909.4
RAS protein-specific guanine nucleotide-releasing factor 1
chr6_+_88724828 1.02 ENSMUST00000089449.2
monoglyceride lipase
chr6_-_72788952 1.02 ENSMUST00000114053.2
transcription factor 7 like 1 (T cell specific, HMG box)
chr6_+_91684061 1.01 ENSMUST00000032185.7
solute carrier family 6 (neurotransmitter transporter, taurine), member 6
chr9_+_48495345 1.01 ENSMUST00000048824.7
predicted gene 5617
chr4_+_123183722 1.00 ENSMUST00000152194.1
hippocalcin-like 4
chr17_+_8525369 0.98 ENSMUST00000115715.1
phosphodiesterase 10A
chr2_+_105127200 0.96 ENSMUST00000139585.1
Wilms tumor 1 homolog
chr11_+_105292637 0.96 ENSMUST00000100335.3
ENSMUST00000021038.4
mannose receptor, C type 2
chr4_+_86053887 0.96 ENSMUST00000107178.2
ENSMUST00000048885.5
ENSMUST00000141889.1
ENSMUST00000120678.1
ADAMTS-like 1
chr6_-_142964404 0.94 ENSMUST00000032421.3
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
chr14_+_118137101 0.94 ENSMUST00000022728.2
G protein-coupled receptor 180
chr1_+_109982710 0.93 ENSMUST00000112701.1
cadherin 7, type 2
chr2_+_135659625 0.93 ENSMUST00000134310.1
phospholipase C, beta 4
chr10_+_42860776 0.91 ENSMUST00000105494.1
sex comb on midleg-like 4 (Drosophila)
chr7_+_100607410 0.91 ENSMUST00000107048.1
ENSMUST00000032946.3
RAB6A, member RAS oncogene family
chr4_-_117872520 0.91 ENSMUST00000171052.1
ENSMUST00000166325.1
ENSMUST00000106422.2
coiled-coil domain containing 24
chr6_-_29179584 0.91 ENSMUST00000159200.1
proline-rich transmembrane protein 4
chr11_-_101785252 0.90 ENSMUST00000164750.1
ENSMUST00000107176.1
ENSMUST00000017868.6
ets variant gene 4 (E1A enhancer binding protein, E1AF)
chr3_+_28263563 0.90 ENSMUST00000160307.2
ENSMUST00000159680.2
ENSMUST00000160518.1
ENSMUST00000162485.1
ENSMUST00000159308.1
ENSMUST00000162777.1
ENSMUST00000161964.1
TRAF2 and NCK interacting kinase
chr11_+_97799565 0.89 ENSMUST00000043843.5
LIM and SH3 protein 1
chr14_+_55765956 0.89 ENSMUST00000057569.3
leukotriene B4 receptor 1
chr1_+_59912972 0.89 ENSMUST00000036540.5
family with sequence similarity 117, member B
chr8_+_85083269 0.88 ENSMUST00000034121.9
mannosidase 2, alpha B1
chr11_+_114851507 0.88 ENSMUST00000177952.1
G protein-coupled receptor, family C, group 5, member C
chr11_-_101894355 0.88 ENSMUST00000057054.7
mesenchyme homeobox 1
chrX_+_140664908 0.87 ENSMUST00000112990.1
ENSMUST00000112988.1
midline 2
chr13_-_94358818 0.86 ENSMUST00000059598.2
predicted gene 9776
chr6_+_83156401 0.86 ENSMUST00000032106.4
RIKEN cDNA 1700003E16 gene
chr7_-_141117772 0.84 ENSMUST00000067836.7
anoctamin 9
chr2_+_153345809 0.84 ENSMUST00000109790.1
additional sex combs like 1
chr7_+_100607660 0.84 ENSMUST00000098252.4
RAB6A, member RAS oncogene family
chrX_+_142681398 0.83 ENSMUST00000112889.1
ENSMUST00000101198.2
ENSMUST00000112891.1
ENSMUST00000087333.2
transmembrane protein 164
chr5_-_92083455 0.82 ENSMUST00000169094.1
ENSMUST00000167918.1
GTPase activating protein (SH3 domain) binding protein 2
chr2_-_118547541 0.82 ENSMUST00000110859.2
BCL2 modifying factor
chr6_+_88724489 0.81 ENSMUST00000113581.1
monoglyceride lipase
chr11_+_100859351 0.80 ENSMUST00000004145.7
ENSMUST00000133036.1
signal transducer and activator of transcription 5A
chr17_-_29237759 0.80 ENSMUST00000137727.1
ENSMUST00000024805.7
copine V
chr6_+_88724462 0.79 ENSMUST00000113582.1
monoglyceride lipase
chr10_-_127751707 0.79 ENSMUST00000079692.5
G protein-coupled receptor 182
chr12_-_86892540 0.79 ENSMUST00000181290.1
predicted gene, 26698
chr11_-_105944412 0.79 ENSMUST00000019734.4
ENSMUST00000184269.1
ENSMUST00000150563.1
cytochrome b-561
chr3_-_104818539 0.78 ENSMUST00000106774.1
ENSMUST00000106775.1
ENSMUST00000166979.1
ENSMUST00000136148.1
Moloney leukemia virus 10
chr11_+_97798995 0.78 ENSMUST00000143571.1
LIM and SH3 protein 1
chr12_+_4234023 0.78 ENSMUST00000179139.1
peptidyl-tRNA hydrolase domain containing 1
chr3_-_101836223 0.78 ENSMUST00000061831.4
mab-21-like 3 (C. elegans)
chr17_+_8849974 0.78 ENSMUST00000115720.1
phosphodiesterase 10A
chr11_-_97996171 0.77 ENSMUST00000042971.9
ADP-ribosylation factor-like 5C
chr1_-_75278345 0.77 ENSMUST00000039534.4
regulated endocrine-specific protein 18
chr17_-_57078490 0.77 ENSMUST00000011623.7
DENN/MADD domain containing 1C
chr7_-_6331235 0.76 ENSMUST00000127658.1
ENSMUST00000062765.7
zinc finger protein 583
chr5_-_137613759 0.76 ENSMUST00000155251.1
ENSMUST00000124693.1
procollagen C-endopeptidase enhancer protein
chr18_-_80713062 0.75 ENSMUST00000170905.1
ENSMUST00000078049.4
nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1
chr5_-_92083667 0.74 ENSMUST00000113127.3
GTPase activating protein (SH3 domain) binding protein 2
chr11_+_66911981 0.74 ENSMUST00000123434.2
phosphoinositide-interacting regulator of transient receptor potential channels
chr11_+_49244191 0.74 ENSMUST00000167400.1
ENSMUST00000081794.6
mannoside acetylglucosaminyltransferase 1
chr7_-_6155939 0.73 ENSMUST00000094870.1
zinc finger protein 787
chr11_+_69088490 0.73 ENSMUST00000021273.6
ENSMUST00000117780.1
vesicle-associated membrane protein 2
chr3_+_138742195 0.73 ENSMUST00000029800.2
tetraspanin 5
chr9_-_50727921 0.73 ENSMUST00000118707.1
ENSMUST00000034566.8
DIX domain containing 1
chr15_-_89477400 0.72 ENSMUST00000165199.1
arylsulfatase A
chr4_+_49059256 0.72 ENSMUST00000076670.2
RIKEN cDNA E130309F12 gene
chr5_+_146231211 0.72 ENSMUST00000161181.1
ENSMUST00000161652.1
ENSMUST00000031640.8
ENSMUST00000159467.1
cyclin-dependent kinase 8
chr11_+_100859492 0.72 ENSMUST00000107356.1
signal transducer and activator of transcription 5A
chr1_-_193241424 0.71 ENSMUST00000162842.1
ENSMUST00000160929.1
hydroxysteroid 11-beta dehydrogenase 1
chr15_+_75993756 0.71 ENSMUST00000089669.4
mitogen-activated protein kinase 15
chr3_-_94473591 0.71 ENSMUST00000029785.3
regulatory subunit of type II PKA R-subunit (RIIa) domain containing 1
chrX_+_69360294 0.70 ENSMUST00000033532.6
AF4/FMR2 family, member 2
chr18_+_76059458 0.70 ENSMUST00000167921.1
zinc finger and BTB domain containing 7C
chr9_-_102354685 0.70 ENSMUST00000035129.7
ENSMUST00000085169.5
Eph receptor B1
chr18_-_25753852 0.69 ENSMUST00000025117.6
ENSMUST00000115816.2
CUGBP, Elav-like family member 4
chr7_-_31055594 0.69 ENSMUST00000039909.6
FXYD domain-containing ion transport regulator 1
chr12_+_61523889 0.68 ENSMUST00000119481.1
ENSMUST00000055815.7
leucine rich repeat and fibronectin type III domain containing 5
chr19_+_6400523 0.66 ENSMUST00000146831.1
ENSMUST00000035716.8
ENSMUST00000138555.1
ENSMUST00000167240.1
RAS, guanyl releasing protein 2
chr11_-_105944128 0.65 ENSMUST00000184086.1
cytochrome b-561
chr2_+_119237531 0.65 ENSMUST00000110817.2
serine protease inhibitor, Kunitz type 1
chr13_+_112800923 0.64 ENSMUST00000070951.6
phosphatidic acid phosphatase type 2A
chr11_+_3983636 0.64 ENSMUST00000078757.1
galactose-3-O-sulfotransferase 1
chr11_+_71750680 0.63 ENSMUST00000021168.7
WSC domain containing 1
chr18_+_49979514 0.62 ENSMUST00000179937.1
tumor necrosis factor, alpha-induced protein 8
chr15_+_80173642 0.62 ENSMUST00000044970.6
mannoside acetylglucosaminyltransferase 3
chr9_+_61372359 0.61 ENSMUST00000178113.1
ENSMUST00000159386.1
transducin-like enhancer of split 3, homolog of Drosophila E(spl)
chr15_+_39745926 0.61 ENSMUST00000022913.4
dentrocyte expressed seven transmembrane protein
chr4_-_134535268 0.61 ENSMUST00000102550.3
mitochondrial fission regulator 1-like
chr2_-_63184253 0.60 ENSMUST00000075052.3
ENSMUST00000112454.1
potassium voltage-gated channel, subfamily H (eag-related), member 7
chr4_-_110292719 0.59 ENSMUST00000106601.1
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 4 (Hu antigen D)
chr5_+_33104219 0.59 ENSMUST00000011178.2
solute carrier family 5 (sodium/glucose cotransporter), member 1
chr7_+_43634718 0.58 ENSMUST00000032663.8
carcinoembryonic antigen-related cell adhesion molecule 18
chr18_-_38866702 0.58 ENSMUST00000115582.1
fibroblast growth factor 1
chr7_+_129257027 0.57 ENSMUST00000094018.4
phosphatidic acid phosphatase type 2 domain containing 1A
chr14_-_31577318 0.57 ENSMUST00000112027.2
collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase
chr9_-_21127346 0.57 ENSMUST00000001036.10
tyrosine kinase 2
chr7_+_31059342 0.57 ENSMUST00000039775.7
leucine-rich repeat LGI family, member 4
chr2_+_119237453 0.57 ENSMUST00000110816.1
serine protease inhibitor, Kunitz type 1
chr2_+_143546144 0.56 ENSMUST00000028905.9
proprotein convertase subtilisin/kexin type 2
chr11_+_28853189 0.56 ENSMUST00000020759.5
epidermal growth factor-containing fibulin-like extracellular matrix protein 1
chr18_+_49979427 0.56 ENSMUST00000148989.2
tumor necrosis factor, alpha-induced protein 8
chr2_+_119237351 0.56 ENSMUST00000028783.7
serine protease inhibitor, Kunitz type 1
chr7_-_141539784 0.56 ENSMUST00000118694.1
ENSMUST00000153191.1
ENSMUST00000166082.1
ENSMUST00000026586.6
chitinase domain containing 1
chr11_+_112782182 0.56 ENSMUST00000000579.2
SRY-box containing gene 9
chr7_+_110772604 0.56 ENSMUST00000005829.6
adenosine monophosphate deaminase 3
chr7_+_110768169 0.56 ENSMUST00000170374.1
adenosine monophosphate deaminase 3

Network of associatons between targets according to the STRING database.

First level regulatory network of Epas1_Bcl3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 4.8 GO:0060300 regulation of cytokine activity(GO:0060300)
0.8 2.3 GO:0010814 substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.8 5.3 GO:0061092 regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
0.6 2.4 GO:0002767 immune response-inhibiting cell surface receptor signaling pathway(GO:0002767)
0.6 3.4 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.6 1.7 GO:2000418 positive regulation of eosinophil migration(GO:2000418)
0.6 3.4 GO:0014826 regulation of systemic arterial blood pressure by endothelin(GO:0003100) vein smooth muscle contraction(GO:0014826)
0.6 1.7 GO:1902809 cornification(GO:0070268) regulation of skeletal muscle fiber differentiation(GO:1902809)
0.5 2.0 GO:0002415 immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
0.5 1.4 GO:0072299 negative regulation of metanephric glomerulus development(GO:0072299) negative regulation of metanephric glomerular mesangial cell proliferation(GO:0072302) regulation of metanephric ureteric bud development(GO:2001074) positive regulation of metanephric ureteric bud development(GO:2001076)
0.5 4.2 GO:0000255 allantoin metabolic process(GO:0000255)
0.5 1.4 GO:0090194 hyaluranon cable assembly(GO:0036118) negative regulation of glomerular mesangial cell proliferation(GO:0072125) negative regulation of glomerulus development(GO:0090194) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.5 1.4 GO:0035771 interleukin-4-mediated signaling pathway(GO:0035771)
0.5 2.3 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.5 2.3 GO:0007207 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.4 2.2 GO:0032277 negative regulation of gonadotropin secretion(GO:0032277) negative regulation of follicle-stimulating hormone secretion(GO:0046882)
0.4 1.7 GO:1905077 negative regulation of interleukin-17 secretion(GO:1905077)
0.4 3.4 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.4 2.6 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.4 2.2 GO:1903278 positive regulation of sodium ion export(GO:1903275) positive regulation of sodium ion export from cell(GO:1903278) positive regulation of inorganic anion transmembrane transport(GO:1903797)
0.4 1.1 GO:0035585 calcium-mediated signaling using extracellular calcium source(GO:0035585)
0.4 1.8 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.3 1.7 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.3 1.0 GO:0046021 regulation of transcription from RNA polymerase II promoter, mitotic(GO:0046021) positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022)
0.3 3.0 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.3 1.3 GO:0098795 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.3 1.2 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.3 0.8 GO:2001226 negative regulation of chloride transport(GO:2001226)
0.3 0.6 GO:0072190 ureter urothelium development(GO:0072190) ureter morphogenesis(GO:0072197)
0.3 1.4 GO:0010958 regulation of amino acid import(GO:0010958)
0.3 1.1 GO:0097167 circadian regulation of translation(GO:0097167)
0.3 1.5 GO:0090292 nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.2 0.7 GO:0060854 patterning of lymph vessels(GO:0060854)
0.2 0.7 GO:0006713 glucocorticoid catabolic process(GO:0006713)
0.2 0.9 GO:0061056 sclerotome development(GO:0061056)
0.2 0.8 GO:0035521 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.2 0.2 GO:0044830 modulation by host of viral RNA genome replication(GO:0044830)
0.2 0.7 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.2 2.0 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.2 0.5 GO:0048007 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.2 1.6 GO:0097623 potassium ion export across plasma membrane(GO:0097623)
0.2 1.3 GO:0098967 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.2 0.5 GO:1901079 positive regulation of relaxation of muscle(GO:1901079)
0.2 2.4 GO:0060294 inner dynein arm assembly(GO:0036159) cilium movement involved in cell motility(GO:0060294)
0.2 0.6 GO:0034241 positive regulation of macrophage fusion(GO:0034241)
0.1 0.9 GO:0007256 activation of JNKK activity(GO:0007256)
0.1 0.6 GO:0008582 regulation of synaptic growth at neuromuscular junction(GO:0008582)
0.1 0.4 GO:0061763 multivesicular body-lysosome fusion(GO:0061763)
0.1 2.3 GO:0014051 gamma-aminobutyric acid secretion(GO:0014051) gamma-aminobutyric acid transport(GO:0015812)
0.1 2.4 GO:0046069 cGMP catabolic process(GO:0046069)
0.1 0.6 GO:0030070 insulin processing(GO:0030070)
0.1 0.7 GO:0035063 nuclear speck organization(GO:0035063)
0.1 0.6 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.1 1.1 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.1 0.7 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
0.1 0.4 GO:0071211 protein targeting to vacuole involved in autophagy(GO:0071211)
0.1 0.4 GO:0002268 follicular dendritic cell activation(GO:0002266) follicular dendritic cell differentiation(GO:0002268)
0.1 0.9 GO:0033600 negative regulation of mammary gland epithelial cell proliferation(GO:0033600)
0.1 0.3 GO:0072199 mesenchymal cell proliferation involved in ureter development(GO:0072198) regulation of mesenchymal cell proliferation involved in ureter development(GO:0072199) positive regulation of mesenchymal cell proliferation involved in ureter development(GO:2000729)
0.1 0.4 GO:0045796 negative regulation of intestinal phytosterol absorption(GO:0010949) negative regulation of intestinal cholesterol absorption(GO:0045796) intestinal phytosterol absorption(GO:0060752) negative regulation of intestinal lipid absorption(GO:1904730)
0.1 1.3 GO:0006751 glutathione catabolic process(GO:0006751)
0.1 0.6 GO:0001951 intestinal D-glucose absorption(GO:0001951)
0.1 0.6 GO:0055095 lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096)
0.1 0.6 GO:0034436 glycoprotein transport(GO:0034436)
0.1 0.9 GO:0032264 IMP salvage(GO:0032264)
0.1 0.6 GO:1901509 regulation of endothelial tube morphogenesis(GO:1901509)
0.1 1.7 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.1 3.2 GO:2000310 regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310)
0.1 0.4 GO:2000182 regulation of progesterone biosynthetic process(GO:2000182)
0.1 0.9 GO:0006013 mannose metabolic process(GO:0006013)
0.1 0.5 GO:1903758 regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.1 0.4 GO:0036015 response to interleukin-3(GO:0036015) cellular response to interleukin-3(GO:0036016)
0.1 1.8 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.1 0.4 GO:0015855 nucleobase transport(GO:0015851) pyrimidine nucleobase transport(GO:0015855)
0.1 0.8 GO:0048102 autophagic cell death(GO:0048102)
0.1 0.5 GO:0010920 negative regulation of inositol phosphate biosynthetic process(GO:0010920) regulation of large conductance calcium-activated potassium channel activity(GO:1902606) positive regulation of large conductance calcium-activated potassium channel activity(GO:1902608)
0.1 2.5 GO:0048268 clathrin coat assembly(GO:0048268)
0.1 1.2 GO:0030322 stabilization of membrane potential(GO:0030322)
0.1 0.4 GO:0032423 regulation of mismatch repair(GO:0032423)
0.1 1.8 GO:0016082 synaptic vesicle priming(GO:0016082)
0.1 0.8 GO:0035372 protein localization to microtubule(GO:0035372)
0.1 0.3 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
0.1 2.4 GO:0032094 response to food(GO:0032094)
0.1 0.5 GO:0002553 histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553)
0.1 2.4 GO:0010107 potassium ion import(GO:0010107)
0.1 0.3 GO:0006788 heme oxidation(GO:0006788)
0.1 0.6 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.1 0.6 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.1 1.1 GO:0006622 protein targeting to lysosome(GO:0006622)
0.1 0.3 GO:0090063 positive regulation of microtubule nucleation(GO:0090063)
0.1 0.9 GO:0019236 response to pheromone(GO:0019236)
0.1 0.7 GO:0090394 negative regulation of excitatory postsynaptic potential(GO:0090394)
0.1 0.4 GO:0032227 negative regulation of synaptic transmission, dopaminergic(GO:0032227)
0.1 1.6 GO:0034063 stress granule assembly(GO:0034063)
0.1 0.2 GO:0001803 antibody-dependent cellular cytotoxicity(GO:0001788) type III hypersensitivity(GO:0001802) regulation of type III hypersensitivity(GO:0001803) positive regulation of type III hypersensitivity(GO:0001805)
0.1 0.2 GO:0003274 endocardial cushion fusion(GO:0003274) positive regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000563)
0.1 0.5 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.1 0.2 GO:0051122 hepoxilin metabolic process(GO:0051121) hepoxilin biosynthetic process(GO:0051122)
0.1 0.4 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.1 0.5 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.7 GO:1903025 regulation of RNA polymerase II regulatory region sequence-specific DNA binding(GO:1903025)
0.0 0.5 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.7 GO:0090209 negative regulation of triglyceride metabolic process(GO:0090209)
0.0 0.1 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.0 0.1 GO:0018199 peptidyl-glutamine modification(GO:0018199)
0.0 0.6 GO:0019370 glutathione biosynthetic process(GO:0006750) leukotriene biosynthetic process(GO:0019370)
0.0 0.2 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.0 0.5 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.0 1.2 GO:0048266 behavioral response to pain(GO:0048266)
0.0 0.7 GO:0015732 prostaglandin transport(GO:0015732)
0.0 0.5 GO:0051481 negative regulation of cytosolic calcium ion concentration(GO:0051481)
0.0 0.3 GO:0048711 positive regulation of astrocyte differentiation(GO:0048711)
0.0 0.4 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.0 0.3 GO:0035878 nail development(GO:0035878)
0.0 0.7 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.1 GO:0031394 positive regulation of prostaglandin biosynthetic process(GO:0031394) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.0 0.6 GO:0031987 locomotion involved in locomotory behavior(GO:0031987)
0.0 0.3 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.0 0.6 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.0 0.5 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.3 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 0.3 GO:0051798 positive regulation of hair follicle development(GO:0051798)
0.0 0.5 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.0 1.6 GO:0030857 negative regulation of epithelial cell differentiation(GO:0030857)
0.0 0.1 GO:1903553 positive regulation of extracellular exosome assembly(GO:1903553)
0.0 0.9 GO:0043267 negative regulation of potassium ion transport(GO:0043267)
0.0 1.0 GO:0015804 neutral amino acid transport(GO:0015804)
0.0 0.2 GO:0072189 ureter development(GO:0072189)
0.0 0.8 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 0.7 GO:1904355 positive regulation of telomere capping(GO:1904355)
0.0 0.7 GO:0007339 binding of sperm to zona pellucida(GO:0007339)
0.0 0.1 GO:2001184 positive regulation of interleukin-12 secretion(GO:2001184)
0.0 0.2 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.0 0.7 GO:0045747 positive regulation of Notch signaling pathway(GO:0045747)
0.0 2.6 GO:0043149 contractile actin filament bundle assembly(GO:0030038) stress fiber assembly(GO:0043149)
0.0 0.1 GO:0099550 trans-synaptic signalling, modulating synaptic transmission(GO:0099550)
0.0 1.4 GO:0002088 lens development in camera-type eye(GO:0002088)
0.0 2.4 GO:0007601 visual perception(GO:0007601)
0.0 0.6 GO:0042551 neuron maturation(GO:0042551)
0.0 1.5 GO:0007338 single fertilization(GO:0007338)
0.0 1.4 GO:0022900 electron transport chain(GO:0022900)
0.0 0.1 GO:0071233 response to leucine(GO:0043201) cellular response to leucine(GO:0071233)
0.0 0.2 GO:0070862 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.0 0.9 GO:0034605 cellular response to heat(GO:0034605)
0.0 0.3 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)
0.0 0.3 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 1.2 GO:0050830 defense response to Gram-positive bacterium(GO:0050830)
0.0 0.1 GO:0033564 Cdc42 protein signal transduction(GO:0032488) anterior/posterior axon guidance(GO:0033564)
0.0 0.9 GO:0007200 phospholipase C-activating G-protein coupled receptor signaling pathway(GO:0007200)
0.0 0.6 GO:0000266 mitochondrial fission(GO:0000266)
0.0 0.7 GO:0008542 visual learning(GO:0008542)
0.0 0.4 GO:0001829 trophectodermal cell differentiation(GO:0001829)
0.0 0.6 GO:0071277 cellular response to calcium ion(GO:0071277)
0.0 0.4 GO:1901998 toxin transport(GO:1901998)
0.0 0.0 GO:0051344 regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051342) negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.0 0.2 GO:0031069 hair follicle morphogenesis(GO:0031069)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 4.1 GO:0071953 elastic fiber(GO:0071953)
0.9 2.6 GO:0070195 growth hormone receptor complex(GO:0070195)
0.7 2.2 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.6 1.7 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.3 1.3 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032) synaptobrevin 2-SNAP-25-syntaxin-1a-complexin II complex(GO:0070033)
0.3 1.1 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.2 2.3 GO:0033093 Weibel-Palade body(GO:0033093)
0.2 1.1 GO:0043202 lysosomal lumen(GO:0043202)
0.2 1.8 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.2 3.4 GO:0031143 pseudopodium(GO:0031143)
0.2 1.8 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.2 1.1 GO:0008091 spectrin(GO:0008091)
0.2 0.8 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.1 0.4 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.1 1.5 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1 1.7 GO:0045179 apical cortex(GO:0045179)
0.1 0.4 GO:0043190 ATP-binding cassette (ABC) transporter complex(GO:0043190)
0.1 2.6 GO:0043196 varicosity(GO:0043196)
0.1 1.8 GO:0012510 trans-Golgi network transport vesicle membrane(GO:0012510)
0.1 1.8 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.1 1.0 GO:0042788 polysomal ribosome(GO:0042788)
0.1 0.5 GO:0030314 junctional membrane complex(GO:0030314)
0.1 0.3 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.1 1.9 GO:0005581 collagen trimer(GO:0005581)
0.1 0.7 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.1 1.6 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.1 2.0 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.1 1.7 GO:0042101 T cell receptor complex(GO:0042101)
0.1 2.3 GO:0032590 dendrite membrane(GO:0032590)
0.0 0.3 GO:0035749 myelin sheath adaxonal region(GO:0035749)
0.0 1.0 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.5 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.0 2.1 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.7 GO:0032433 filopodium tip(GO:0032433)
0.0 0.7 GO:0034385 very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.0 0.1 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.5 GO:0071564 npBAF complex(GO:0071564)
0.0 0.3 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.0 0.3 GO:0005869 dynactin complex(GO:0005869)
0.0 0.4 GO:0032156 septin cytoskeleton(GO:0032156)
0.0 2.4 GO:0036126 sperm flagellum(GO:0036126)
0.0 0.2 GO:0097208 alveolar lamellar body(GO:0097208)
0.0 1.8 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 2.0 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.1 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.0 0.5 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 7.3 GO:0005578 proteinaceous extracellular matrix(GO:0005578)
0.0 0.1 GO:0042583 chromaffin granule(GO:0042583)
0.0 0.7 GO:0016592 mediator complex(GO:0016592)
0.0 2.4 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 1.3 GO:0030315 T-tubule(GO:0030315)
0.0 1.2 GO:0001669 acrosomal vesicle(GO:0001669)
0.0 0.8 GO:0031519 PcG protein complex(GO:0031519)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.4 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
0.9 2.6 GO:0004903 growth hormone receptor activity(GO:0004903)
0.8 3.4 GO:0031708 endothelin B receptor binding(GO:0031708)
0.7 2.2 GO:0005118 sevenless binding(GO:0005118)
0.6 2.3 GO:0004985 opioid receptor activity(GO:0004985)
0.5 2.5 GO:0032450 maltose alpha-glucosidase activity(GO:0032450)
0.5 1.4 GO:0022865 transmembrane electron transfer carrier(GO:0022865)
0.5 2.3 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.4 2.9 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.4 1.2 GO:0031750 D3 dopamine receptor binding(GO:0031750) D5 dopamine receptor binding(GO:0031752)
0.3 1.0 GO:0030977 taurine binding(GO:0030977)
0.3 1.6 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.3 2.5 GO:0032051 clathrin light chain binding(GO:0032051)
0.3 0.9 GO:0004974 leukotriene receptor activity(GO:0004974)
0.3 1.3 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.2 0.7 GO:0001225 RNA polymerase II transcription coactivator binding(GO:0001225)
0.2 1.7 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.2 0.7 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.2 1.7 GO:1990380 Lys63-specific deubiquitinase activity(GO:0061578) Lys48-specific deubiquitinase activity(GO:1990380)
0.2 4.6 GO:0005540 hyaluronic acid binding(GO:0005540)
0.2 1.8 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.2 0.6 GO:0034189 very-low-density lipoprotein particle binding(GO:0034189) glycoprotein transporter activity(GO:0034437)
0.2 2.1 GO:0036122 BMP binding(GO:0036122)
0.2 0.8 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.2 0.6 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.2 0.7 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.2 0.5 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.2 1.4 GO:0010385 double-stranded methylated DNA binding(GO:0010385)
0.2 5.3 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.2 2.6 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.2 1.4 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.2 1.5 GO:0034711 inhibin binding(GO:0034711)
0.2 0.6 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733)
0.2 0.9 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.1 0.6 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.1 0.4 GO:0004698 calcium-dependent protein kinase C activity(GO:0004698)
0.1 2.4 GO:0030547 receptor inhibitor activity(GO:0030547)
0.1 0.6 GO:0004568 chitinase activity(GO:0004568)
0.1 0.4 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.1 1.8 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.1 1.1 GO:0015245 fatty acid transporter activity(GO:0015245)
0.1 0.4 GO:0015389 pyrimidine- and adenine-specific:sodium symporter activity(GO:0015389)
0.1 0.9 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 3.9 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.1 1.7 GO:0044548 S100 protein binding(GO:0044548)
0.1 1.5 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 3.0 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.1 2.0 GO:0034483 heparan sulfate sulfotransferase activity(GO:0034483)
0.1 1.7 GO:0001972 retinoic acid binding(GO:0001972)
0.1 0.6 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.1 0.5 GO:0055100 adiponectin binding(GO:0055100)
0.1 0.5 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.1 0.8 GO:0097642 calcitonin family receptor activity(GO:0097642)
0.1 0.5 GO:0004103 choline kinase activity(GO:0004103)
0.1 0.6 GO:0005131 growth hormone receptor binding(GO:0005131)
0.1 0.3 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.1 0.7 GO:0008046 axon guidance receptor activity(GO:0008046)
0.1 1.7 GO:0031489 myosin V binding(GO:0031489)
0.1 0.6 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.1 0.9 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.1 5.2 GO:0048365 Rac GTPase binding(GO:0048365)
0.1 1.5 GO:0005521 lamin binding(GO:0005521)
0.1 0.3 GO:0001640 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640)
0.1 0.9 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.1 1.1 GO:0004707 MAP kinase activity(GO:0004707)
0.1 0.9 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.1 0.4 GO:0031685 adenosine receptor binding(GO:0031685)
0.1 0.3 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.1 3.1 GO:0017022 myosin binding(GO:0017022)
0.0 1.2 GO:0070001 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 0.1 GO:0004052 arachidonate 12-lipoxygenase activity(GO:0004052)
0.0 0.5 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.0 0.2 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.0 1.5 GO:0005035 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.8 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 2.5 GO:0019003 GDP binding(GO:0019003)
0.0 0.9 GO:0004629 phosphatidylinositol phospholipase C activity(GO:0004435) phospholipase C activity(GO:0004629)
0.0 4.3 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.3 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.3 GO:0038132 neuregulin binding(GO:0038132)
0.0 0.4 GO:0002151 G-quadruplex RNA binding(GO:0002151)
0.0 0.2 GO:0019770 IgG receptor activity(GO:0019770)
0.0 0.8 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 1.2 GO:0008146 sulfotransferase activity(GO:0008146)
0.0 0.7 GO:0035613 RNA stem-loop binding(GO:0035613)
0.0 1.1 GO:0017091 AU-rich element binding(GO:0017091)
0.0 1.1 GO:0071837 HMG box domain binding(GO:0071837)
0.0 1.3 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 4.7 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.5 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 2.9 GO:0000979 RNA polymerase II core promoter sequence-specific DNA binding(GO:0000979)
0.0 0.3 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.3 GO:0048185 activin binding(GO:0048185)
0.0 0.5 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.0 0.8 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.8 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.4 GO:0070411 I-SMAD binding(GO:0070411)
0.0 2.9 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.3 GO:0004017 adenylate kinase activity(GO:0004017)
0.0 0.8 GO:0016504 peptidase activator activity(GO:0016504)
0.0 0.5 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.1 GO:0045545 syndecan binding(GO:0045545)
0.0 0.5 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 0.8 GO:0043028 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027) cysteine-type endopeptidase regulator activity involved in apoptotic process(GO:0043028)
0.0 0.7 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.0 GO:0036004 GAF domain binding(GO:0036004)
0.0 0.8 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.5 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.0 0.1 GO:0004065 arylsulfatase activity(GO:0004065)
0.0 0.1 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
0.0 2.3 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.1 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.4 GO:0017127 cholesterol transporter activity(GO:0017127)
0.0 0.7 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 2.1 GO:0004386 helicase activity(GO:0004386)
0.0 0.1 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 1.1 GO:0002020 protease binding(GO:0002020)
0.0 0.7 GO:0005518 collagen binding(GO:0005518)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 6.1 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.1 1.4 PID ALK2 PATHWAY ALK2 signaling events
0.1 0.6 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.1 0.3 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 2.1 ST G ALPHA S PATHWAY G alpha s Pathway
0.1 3.4 PID ARF6 PATHWAY Arf6 signaling events
0.1 1.7 PID IL5 PATHWAY IL5-mediated signaling events
0.1 1.1 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.1 1.4 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.0 3.6 PID ENDOTHELIN PATHWAY Endothelins
0.0 2.6 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 1.3 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 1.1 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 0.9 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.7 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 0.4 ST TUMOR NECROSIS FACTOR PATHWAY Tumor Necrosis Factor Pathway.
0.0 3.1 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 4.8 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.5 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 0.6 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.4 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.5 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.9 PID TNF PATHWAY TNF receptor signaling pathway
0.0 0.1 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 0.7 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.4 PID NOTCH PATHWAY Notch signaling pathway
0.0 0.6 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.5 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.3 5.3 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.3 3.4 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.2 4.2 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.2 1.5 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.2 1.7 REACTOME ROLE OF DCC IN REGULATING APOPTOSIS Genes involved in Role of DCC in regulating apoptosis
0.1 3.1 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.1 4.9 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.1 1.7 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.1 1.2 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.1 4.2 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.1 2.6 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1 5.3 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.1 2.9 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.1 3.1 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.1 2.8 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.1 1.7 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.1 0.7 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.1 2.3 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.1 1.9 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.1 0.7 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.1 0.6 REACTOME NOREPINEPHRINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Norepinephrine Neurotransmitter Release Cycle
0.1 2.6 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.1 2.7 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.1 0.9 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 0.9 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.6 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.0 1.7 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 1.8 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.8 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 1.0 REACTOME RAP1 SIGNALLING Genes involved in Rap1 signalling
0.0 1.2 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 5.4 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 1.4 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.6 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.0 1.5 REACTOME PLC BETA MEDIATED EVENTS Genes involved in PLC beta mediated events
0.0 0.5 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 1.4 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 1.1 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.5 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.0 0.6 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 4.9 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.5 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 1.5 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 2.4 REACTOME PPARA ACTIVATES GENE EXPRESSION Genes involved in PPARA Activates Gene Expression
0.0 1.0 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 0.5 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.2 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.4 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.4 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 1.2 REACTOME L1CAM INTERACTIONS Genes involved in L1CAM interactions
0.0 0.3 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.7 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.2 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.3 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.4 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.1 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.2 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.3 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.4 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules