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2D miR_HR1_12

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Results for Fosb

Z-value: 0.59

Motif logo

Transcription factors associated with Fosb

Gene Symbol Gene ID Gene Info
ENSMUSG00000003545.2 FBJ osteosarcoma oncogene B

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Fosbmm10_v2_chr7_-_19310035_193100500.528.0e-02Click!

Activity profile of Fosb motif

Sorted Z-values of Fosb motif

Promoter Log-likelihood Transcript Gene Gene Info
chr10_+_88091070 1.41 ENSMUST00000048621.7
pro-melanin-concentrating hormone
chr7_-_4778141 1.29 ENSMUST00000094892.5
interleukin 11
chr5_-_24392012 1.25 ENSMUST00000059401.6
autophagy related 9B
chr3_-_88503187 0.80 ENSMUST00000120377.1
lamin A
chr9_+_7272514 0.78 ENSMUST00000015394.8
matrix metallopeptidase 13
chr8_-_41215146 0.76 ENSMUST00000034003.4
fibrinogen-like protein 1
chr3_-_88503331 0.70 ENSMUST00000029699.6
lamin A
chr5_-_21785115 0.70 ENSMUST00000115193.1
ENSMUST00000115192.1
ENSMUST00000115195.1
ENSMUST00000030771.5
DnaJ (Hsp40) homolog, subfamily C, member 2
chr1_-_12991109 0.69 ENSMUST00000115403.2
ENSMUST00000115402.1
solute carrier organic anion transporter family, member 5A1
chr2_+_167777467 0.69 ENSMUST00000139927.1
ENSMUST00000127441.1
predicted gene 14321
chr14_-_55758458 0.66 ENSMUST00000001497.7
cell death-inducing DNA fragmentation factor, alpha subunit-like effector B
chr17_-_45592485 0.60 ENSMUST00000166119.1
solute carrier family 29 (nucleoside transporters), member 1
chr11_-_99155067 0.56 ENSMUST00000103134.3
chemokine (C-C motif) receptor 7
chr17_-_45592262 0.56 ENSMUST00000164769.1
solute carrier family 29 (nucleoside transporters), member 1
chr1_+_40515362 0.49 ENSMUST00000027237.5
interleukin 18 receptor accessory protein
chrX_+_73675500 0.48 ENSMUST00000171398.1
solute carrier family 6 (neurotransmitter transporter, creatine), member 8
chr18_+_4994600 0.47 ENSMUST00000140448.1
supervillin
chr14_+_27622433 0.47 ENSMUST00000090302.5
ELKS/RAB6-interacting/CAST family member 2
chr7_+_127800844 0.46 ENSMUST00000106271.1
ENSMUST00000138432.1
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 7
chr15_+_102503722 0.46 ENSMUST00000096145.4
predicted gene 10337
chr17_+_47769191 0.39 ENSMUST00000160373.1
ENSMUST00000159641.1
transcription factor EB
chr11_-_70015346 0.39 ENSMUST00000018718.7
ENSMUST00000102574.3
acyl-Coenzyme A dehydrogenase, very long chain
chr2_-_25224653 0.37 ENSMUST00000043584.4
tubulin, beta 4B class IVB
chr18_+_40258361 0.37 ENSMUST00000091927.4
potassium channel tetramerisation domain containing 16
chr4_-_43558386 0.36 ENSMUST00000130353.1
talin 1
chr11_-_120630516 0.36 ENSMUST00000106181.1
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein G (avian)
chr17_+_35841491 0.35 ENSMUST00000082337.6
mediator of DNA damage checkpoint 1
chr9_-_109059216 0.34 ENSMUST00000112053.1
three prime repair exonuclease 1
chr11_-_3914664 0.34 ENSMUST00000109995.1
ENSMUST00000051207.1
solute carrier family 35, member E4
chr7_-_80401707 0.33 ENSMUST00000120753.1
furin (paired basic amino acid cleaving enzyme)
chr11_+_80428598 0.31 ENSMUST00000173938.1
ENSMUST00000017572.7
proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
chr9_+_78615501 0.28 ENSMUST00000093812.4
CD109 antigen
chr2_+_151572606 0.28 ENSMUST00000028950.8
syndecan binding protein (syntenin) 2
chr11_-_100397740 0.27 ENSMUST00000001592.8
ENSMUST00000107403.1
junction plakoglobin
chr10_-_86011833 0.26 ENSMUST00000105304.1
ENSMUST00000061699.5
BPI fold containing family C
chr1_+_165769392 0.26 ENSMUST00000040298.4
cellular repressor of E1A-stimulated genes 1
chr4_-_19922599 0.25 ENSMUST00000029900.5
ATPase, H+ transporting, lysosomal V0 subunit D2
chr17_+_78508063 0.25 ENSMUST00000024880.9
vitrin
chr17_+_35841668 0.24 ENSMUST00000174124.1
mediator of DNA damage checkpoint 1
chr11_-_69666062 0.24 ENSMUST00000108654.2
ENSMUST00000018918.5
CD68 antigen
chr1_+_86064619 0.23 ENSMUST00000027432.8
proteasome (prosome, macropain) 26S subunit, non-ATPase, 1
chr6_+_42349826 0.22 ENSMUST00000070635.6
zyxin
chr9_-_109059711 0.22 ENSMUST00000061973.4
three prime repair exonuclease 1
chr9_+_96259246 0.21 ENSMUST00000179065.1
ENSMUST00000165768.2
transcription factor Dp 2
chr11_-_69549108 0.21 ENSMUST00000108659.1
dynein, axonemal, heavy chain 2
chr19_-_32210969 0.21 ENSMUST00000151289.1
sphingomyelin synthase 1
chr11_-_109473598 0.20 ENSMUST00000070152.5
solute carrier family 16 (monocarboxylic acid transporters), member 6
chr12_+_83632208 0.20 ENSMUST00000048155.9
ENSMUST00000182618.1
ENSMUST00000183154.1
ENSMUST00000182036.1
ENSMUST00000182347.1
RNA binding motif protein 25
chr11_-_102365111 0.19 ENSMUST00000006749.9
solute carrier family 4 (anion exchanger), member 1
chr12_-_84194007 0.18 ENSMUST00000110294.1
ELM2 and Myb/SANT-like domain containing 1
chr2_+_30441831 0.18 ENSMUST00000131476.1
protein phosphatase 2A, regulatory subunit B (PR 53)
chr3_+_116878227 0.18 ENSMUST00000040260.6
ferric-chelate reductase 1
chr1_-_171240055 0.18 ENSMUST00000131286.1
NADH dehydrogenase (ubiquinone) Fe-S protein 2
chr9_-_32541589 0.17 ENSMUST00000016231.7
Friend leukemia integration 1
chr16_+_78930940 0.16 ENSMUST00000114216.1
ENSMUST00000069148.6
ENSMUST00000023568.7
chondrolectin
chr6_-_113934679 0.16 ENSMUST00000101044.2
ATPase, Ca++ transporting, plasma membrane 2
chr4_+_42158092 0.15 ENSMUST00000098122.2
predicted gene 13306
chr12_-_85288419 0.12 ENSMUST00000121930.1
acylphosphatase 1, erythrocyte (common) type
chr10_-_44458687 0.12 ENSMUST00000105490.2
PR domain containing 1, with ZNF domain
chr12_+_51690966 0.12 ENSMUST00000021338.8
adaptor-related protein complex AP-4, sigma 1
chr9_+_96258697 0.12 ENSMUST00000179416.1
transcription factor Dp 2
chr6_-_129533267 0.11 ENSMUST00000181594.1
RIKEN cDNA 1700101I11 gene
chr6_+_42350000 0.11 ENSMUST00000164375.1
zyxin
chr7_-_127946725 0.11 ENSMUST00000118755.1
ENSMUST00000094026.3
protease, serine, 36
chr11_-_43747963 0.10 ENSMUST00000048578.2
ENSMUST00000109278.1
tetratricopeptide repeat domain 1
chr11_+_77801325 0.10 ENSMUST00000151373.2
ENSMUST00000172303.2
ENSMUST00000130305.2
ENSMUST00000164334.1
ENSMUST00000092884.4
myosin XVIIIA
chr15_-_76014318 0.10 ENSMUST00000060807.5
family with sequence similarity 83, member H
chr2_-_45110241 0.09 ENSMUST00000177302.1
zinc finger E-box binding homeobox 2
chr5_-_62766153 0.09 ENSMUST00000076623.4
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr11_+_77801291 0.08 ENSMUST00000100794.3
myosin XVIIIA
chr7_-_105787567 0.08 ENSMUST00000144189.1
dachsous 1 (Drosophila)
chr17_-_35697971 0.08 ENSMUST00000146472.1
discoidin domain receptor family, member 1
chr11_+_4257557 0.08 ENSMUST00000066283.5
leukemia inhibitory factor
chr9_+_7347374 0.07 ENSMUST00000065079.5
ENSMUST00000005950.5
matrix metallopeptidase 12
chrX_+_96455359 0.07 ENSMUST00000033553.7
hephaestin
chr3_+_109573907 0.06 ENSMUST00000106576.2
vav 3 oncogene
chr11_-_99322943 0.06 ENSMUST00000038004.2
keratin 25
chr18_+_61639542 0.06 ENSMUST00000183083.1
ENSMUST00000183087.1
predicted gene, 20748
chr2_+_110721340 0.05 ENSMUST00000111016.2
mucin 15
chr19_+_4139799 0.05 ENSMUST00000096338.3
G protein-coupled receptor 152
chr19_+_5447692 0.05 ENSMUST00000025850.5
fos-like antigen 1
chr7_-_133782721 0.04 ENSMUST00000063669.1
DEAH (Asp-Glu-Ala-His) box polypeptide 32
chr2_+_110721587 0.04 ENSMUST00000111017.2
mucin 15
chr3_+_123267445 0.03 ENSMUST00000047923.7
Sec24 related gene family, member D (S. cerevisiae)
chr8_-_110039330 0.03 ENSMUST00000109222.2
carbohydrate (chondroitin 6/keratan) sulfotransferase 4
chr2_+_52038005 0.03 ENSMUST00000065927.5
tumor necrosis factor alpha induced protein 6
chr17_-_30612613 0.03 ENSMUST00000167624.1
ENSMUST00000024823.6
glyoxalase 1
chr7_+_128129536 0.02 ENSMUST00000033053.6
integrin alpha X
chr7_+_126776939 0.02 ENSMUST00000038614.5
ENSMUST00000170882.1
ENSMUST00000106359.1
ENSMUST00000106357.1
ENSMUST00000145762.1
ENSMUST00000132643.1
ENSMUST00000106356.1
yippee-like 3 (Drosophila)
chr2_+_156475803 0.02 ENSMUST00000029155.8
erythrocyte protein band 4.1-like 1
chr13_-_113663670 0.02 ENSMUST00000054650.4
heat shock protein 3
chrX_-_23266751 0.02 ENSMUST00000115316.2
kelch-like 13
chr13_+_15463837 0.01 ENSMUST00000110510.3
GLI-Kruppel family member GLI3
chr17_+_35049966 0.01 ENSMUST00000007257.9
chloride intracellular channel 1
chr9_+_44240668 0.01 ENSMUST00000092426.3
coiled-coil domain containing 153
chr18_+_42053692 0.00 ENSMUST00000074679.3
SH3 domain containing ring finger 2

Network of associatons between targets according to the STRING database.

First level regulatory network of Fosb

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0046005 positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
0.3 1.5 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.3 1.3 GO:0044805 late nucleophagy(GO:0044805)
0.2 0.8 GO:0090187 positive regulation of pancreatic juice secretion(GO:0090187)
0.2 0.6 GO:2000410 lymphocyte migration into lymphoid organs(GO:0097021) regulation of thymocyte migration(GO:2000410) positive regulation of thymocyte migration(GO:2000412) regulation of dendritic cell dendrite assembly(GO:2000547)
0.2 1.2 GO:0015862 uridine transport(GO:0015862)
0.2 0.5 GO:0015881 creatine transport(GO:0015881)
0.1 0.4 GO:1902477 defense response to bacterium, incompatible interaction(GO:0009816) regulation of defense response to bacterium, incompatible interaction(GO:1902477)
0.1 0.3 GO:0090472 dibasic protein processing(GO:0090472)
0.1 0.5 GO:0035754 B cell chemotaxis(GO:0035754)
0.1 0.3 GO:0072675 osteoclast fusion(GO:0072675)
0.0 0.2 GO:1903028 regulation of opsonization(GO:1903027) positive regulation of opsonization(GO:1903028)
0.0 0.4 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.3 GO:0071681 response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681)
0.0 0.4 GO:0042760 very long-chain fatty acid catabolic process(GO:0042760)
0.0 0.8 GO:0035634 response to stilbenoid(GO:0035634)
0.0 0.2 GO:0048840 otolith development(GO:0048840)
0.0 0.7 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.1 GO:0033078 extrathymic T cell differentiation(GO:0033078)
0.0 0.2 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.1 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
0.0 0.3 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.1 GO:0072108 positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis(GO:0072108)
0.0 0.1 GO:0021767 mammillary body development(GO:0021767) mammillary axonal complex development(GO:0061373) positive regulation of lens fiber cell differentiation(GO:1902748)
0.0 0.7 GO:2000279 negative regulation of DNA biosynthetic process(GO:2000279)
0.0 0.1 GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.0 1.3 GO:0046888 negative regulation of hormone secretion(GO:0046888)
0.0 0.6 GO:0035458 cellular response to interferon-beta(GO:0035458)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.5 GO:0005638 lamin filament(GO:0005638)
0.1 0.8 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.4 GO:0045298 tubulin complex(GO:0045298)
0.0 0.3 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 1.1 GO:0000407 pre-autophagosomal structure(GO:0000407)
0.0 0.3 GO:0071664 catenin-TCF7L2 complex(GO:0071664)
0.0 0.2 GO:0036156 inner dynein arm(GO:0036156)
0.0 0.2 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.3 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 0.2 GO:0031597 cytosolic proteasome complex(GO:0031597)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0005308 creatine transmembrane transporter activity(GO:0005308)
0.1 0.4 GO:0017099 very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099)
0.1 0.7 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.1 0.6 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.1 0.5 GO:0004908 interleukin-1 receptor activity(GO:0004908)
0.1 0.6 GO:0019957 C-C chemokine binding(GO:0019957)
0.1 0.2 GO:0030899 calcium-dependent ATPase activity(GO:0030899)
0.0 1.4 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.0 1.5 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.5 GO:0003854 3-beta-hydroxy-delta5-steroid dehydrogenase activity(GO:0003854)
0.0 0.2 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 1.2 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.0 0.1 GO:0003998 acylphosphatase activity(GO:0003998)
0.0 0.4 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.7 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.2 GO:0000293 ferric-chelate reductase activity(GO:0000293)
0.0 0.3 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.8 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.0 0.1 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
0.0 0.1 GO:1990254 keratin filament binding(GO:1990254)
0.0 0.3 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.3 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 0.2 GO:0005452 inorganic anion exchanger activity(GO:0005452)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.5 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.6 PID ATM PATHWAY ATM pathway
0.0 0.6 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.0 0.4 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 0.5 PID IL23 PATHWAY IL23-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 2.2 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.6 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 1.2 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.3 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.4 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 2.0 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.5 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)