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2D miR_HR1_12

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Results for Mbd2

Z-value: 0.77

Motif logo

Transcription factors associated with Mbd2

Gene Symbol Gene ID Gene Info
ENSMUSG00000024513.10 methyl-CpG binding domain protein 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Mbd2mm10_v2_chr18_+_70568189_70568398-0.855.4e-04Click!

Activity profile of Mbd2 motif

Sorted Z-values of Mbd2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr4_+_137277489 2.16 ENSMUST00000045747.4
wingless-related MMTV integration site 4
chr5_+_30588078 1.93 ENSMUST00000066295.2
potassium channel, subfamily K, member 3
chr5_+_137288273 1.19 ENSMUST00000024099.4
ENSMUST00000085934.3
acetylcholinesterase
chr11_+_85832551 0.93 ENSMUST00000000095.6
T-box 2
chr13_-_34345174 0.87 ENSMUST00000040336.5
solute carrier family 22, member 23
chr2_+_157914618 0.86 ENSMUST00000109523.1
V-set and transmembrane domain containing 2-like
chr11_-_102296618 0.84 ENSMUST00000107132.2
ENSMUST00000073234.2
ataxin 7-like 3
chr2_+_28205648 0.82 ENSMUST00000102879.3
ENSMUST00000028177.4
olfactomedin 1
chr6_+_88198656 0.81 ENSMUST00000015197.7
GATA binding protein 2
chr11_-_69122589 0.79 ENSMUST00000180487.1
RIKEN cDNA 9130213A22 gene
chr6_-_4747157 0.78 ENSMUST00000090686.4
ENSMUST00000115579.1
ENSMUST00000115577.2
ENSMUST00000101677.3
ENSMUST00000004750.8
sarcoglycan, epsilon
chr1_-_74885322 0.78 ENSMUST00000159232.1
ENSMUST00000068631.3
FEV (ETS oncogene family)
chr11_-_119086221 0.77 ENSMUST00000026665.7
chromobox 4
chr15_-_75566608 0.75 ENSMUST00000163116.1
ENSMUST00000023241.5
lymphocyte antigen 6 complex, locus H
chr11_-_89302545 0.75 ENSMUST00000061728.3
noggin
chr11_-_94474088 0.74 ENSMUST00000107786.1
ENSMUST00000107791.1
ENSMUST00000103166.2
ENSMUST00000107792.1
ENSMUST00000100561.3
ENSMUST00000107793.1
ENSMUST00000107788.1
ENSMUST00000107790.1
ENSMUST00000107789.1
ENSMUST00000107785.1
ENSMUST00000021234.8
calcium channel, voltage-dependent, T type, alpha 1G subunit
chr1_+_74854954 0.73 ENSMUST00000160379.2
cyclin-dependent kinase 5, regulatory subunit 2 (p39)
chr17_+_83215271 0.70 ENSMUST00000170794.1
protein kinase domain containing, cytoplasmic
chr3_-_57847478 0.68 ENSMUST00000120289.1
ENSMUST00000066882.8
profilin 2
chr6_-_4747019 0.67 ENSMUST00000126151.1
ENSMUST00000133306.1
ENSMUST00000123907.1
sarcoglycan, epsilon
chr15_-_75566811 0.64 ENSMUST00000065417.8
lymphocyte antigen 6 complex, locus H
chr4_-_140246751 0.64 ENSMUST00000039331.8
immunoglobulin superfamily, member 21
chr4_+_149586432 0.62 ENSMUST00000105691.1
calsyntenin 1
chr16_+_20733104 0.60 ENSMUST00000115423.1
ENSMUST00000007171.6
chordin
chr6_-_72789240 0.59 ENSMUST00000069536.5
transcription factor 7 like 1 (T cell specific, HMG box)
chr15_-_75747922 0.59 ENSMUST00000062002.4
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein A (avian)
chr4_+_149586555 0.57 ENSMUST00000039144.6
calsyntenin 1
chr11_-_102447647 0.57 ENSMUST00000049057.4
family with sequence similarity 171, member A2
chr16_-_22163299 0.56 ENSMUST00000100052.4
insulin-like growth factor 2 mRNA binding protein 2
chr1_+_74601441 0.55 ENSMUST00000087183.4
ENSMUST00000148456.1
ENSMUST00000113694.1
serine/threonine kinase 36
chr13_-_52981027 0.54 ENSMUST00000071065.7
nuclear factor, interleukin 3, regulated
chr11_-_106160101 0.54 ENSMUST00000045923.3
LIM domain containing 2
chr2_-_180954676 0.53 ENSMUST00000148905.1
ENSMUST00000103053.3
ENSMUST00000108873.2
Na+/K+ transporting ATPase interacting 4
chr2_-_94406647 0.53 ENSMUST00000111237.2
ENSMUST00000094801.4
ENSMUST00000111238.1
tetratricopeptide repeat domain 17
chr2_+_28192971 0.51 ENSMUST00000113920.1
olfactomedin 1
chr6_-_72788952 0.51 ENSMUST00000114053.2
transcription factor 7 like 1 (T cell specific, HMG box)
chr1_-_74951651 0.50 ENSMUST00000164097.1
Indian hedgehog
chr12_-_79007276 0.49 ENSMUST00000056660.6
ENSMUST00000174721.1
transmembrane protein 229B
chr1_+_74601548 0.48 ENSMUST00000087186.4
serine/threonine kinase 36
chr7_-_70360593 0.46 ENSMUST00000032768.7
nuclear receptor subfamily 2, group F, member 2
chr17_+_57249450 0.45 ENSMUST00000019631.9
thyroid hormone receptor interactor 10
chr2_-_153529941 0.45 ENSMUST00000035346.7
RIKEN cDNA 8430427H17 gene
chr8_+_127063893 0.44 ENSMUST00000162309.1
par-3 (partitioning defective 3) homolog (C. elegans)
chr14_+_30715599 0.44 ENSMUST00000054230.4
Scm-like with four mbt domains 1
chr11_+_69765899 0.44 ENSMUST00000108640.1
ENSMUST00000108639.1
zinc finger and BTB domain containing 4
chr11_-_106159902 0.44 ENSMUST00000064545.4
LIM domain containing 2
chr2_+_28193093 0.43 ENSMUST00000100244.3
olfactomedin 1
chr4_-_151861762 0.43 ENSMUST00000097774.2
calmodulin binding transcription activator 1
chr9_-_44320229 0.43 ENSMUST00000065080.8
C2 calcium-dependent domain containing 2-like
chr18_-_16809233 0.42 ENSMUST00000025166.7
cadherin 2
chr11_+_57645417 0.42 ENSMUST00000066987.7
ENSMUST00000108846.1
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 10
chr18_-_25169007 0.42 ENSMUST00000115817.2
tubulin polyglutamylase complex subunit 2
chr11_+_69765970 0.42 ENSMUST00000108642.1
ENSMUST00000156932.1
zinc finger and BTB domain containing 4
chr11_-_96829959 0.42 ENSMUST00000081775.5
nuclear factor, erythroid derived 2,-like 1
chr4_+_152096719 0.42 ENSMUST00000105661.3
ENSMUST00000084115.3
pleckstrin homology domain containing, family G (with RhoGef domain) member 5
chr3_-_117868930 0.41 ENSMUST00000029639.5
sorting nexin 7
chr17_+_8801742 0.41 ENSMUST00000089085.2
phosphodiesterase 10A
chr4_-_120747248 0.40 ENSMUST00000030376.7
potassium voltage-gated channel, subfamily Q, member 4
chr4_-_151861698 0.40 ENSMUST00000049790.7
calmodulin binding transcription activator 1
chr2_+_78869009 0.39 ENSMUST00000028398.7
ubiquitin-conjugating enzyme E2E 3
chr2_-_173276526 0.38 ENSMUST00000036248.6
prostate transmembrane protein, androgen induced 1
chr11_-_61267177 0.38 ENSMUST00000066277.3
ENSMUST00000074127.7
ENSMUST00000108715.2
aldehyde dehydrogenase family 3, subfamily A2
chr6_+_125145235 0.38 ENSMUST00000119527.1
ENSMUST00000088276.6
ENSMUST00000051171.7
ENSMUST00000117675.1
intermediate filament family orphan 1
chr19_+_4097392 0.37 ENSMUST00000174514.1
ENSMUST00000174149.1
CDK2-associated protein 2
chr17_+_69417441 0.37 ENSMUST00000097289.2
RIKEN cDNA C030034I22 gene
chr15_+_87625214 0.37 ENSMUST00000068088.6
family with sequence similarity 19, member A5
chr9_-_107635330 0.37 ENSMUST00000055704.6
guanine nucleotide binding protein (G protein), alpha inhibiting 2
chr17_+_46161021 0.36 ENSMUST00000024748.7
ENSMUST00000172170.1
GTP binding protein 2
chr14_-_24245913 0.36 ENSMUST00000073687.6
ENSMUST00000090398.4
discs, large homolog 5 (Drosophila)
chr6_-_126740151 0.35 ENSMUST00000112242.1
potassium voltage-gated channel, shaker-related, subfamily, member 6
chr11_-_96829904 0.35 ENSMUST00000107657.1
nuclear factor, erythroid derived 2,-like 1
chr13_-_43480973 0.35 ENSMUST00000144326.2
RAN binding protein 9
chr14_+_45219993 0.35 ENSMUST00000146150.1
G protein-coupled receptor 137C
chr5_+_114568016 0.34 ENSMUST00000043650.7
family with sequence similarity 222, member A
chr15_-_31367527 0.34 ENSMUST00000076942.4
ENSMUST00000123325.1
ENSMUST00000110410.2
ankyrin repeat domain 33B
chr18_-_58209926 0.34 ENSMUST00000025497.6
fibrillin 2
chr4_+_42949814 0.34 ENSMUST00000037872.3
ENSMUST00000098112.2
DnaJ (Hsp40) homolog, subfamily B, member 5
chr5_+_115631902 0.34 ENSMUST00000031492.8
RAB35, member RAS oncogene family
chr11_-_30954080 0.33 ENSMUST00000073192.7
endoplasmic reticulum lectin 1
chr17_-_34031684 0.33 ENSMUST00000169397.1
solute carrier family 39 (zinc transporter), member 7
chr14_+_20707548 0.33 ENSMUST00000022358.7
zinc finger SWIM-type containing 8
chr11_-_120624973 0.33 ENSMUST00000106183.2
ENSMUST00000080202.5
sirtuin 7
chr4_+_133039482 0.33 ENSMUST00000105914.1
AT hook, DNA binding motif, containing 1
chr7_+_134670667 0.33 ENSMUST00000084488.4
dedicator of cytokinesis 1
chr6_-_120493807 0.32 ENSMUST00000178687.1
cat eye syndrome chromosome region, candidate 6
chr13_-_55362782 0.32 ENSMUST00000021940.7
lectin, mannose-binding 2
chr4_+_43669266 0.32 ENSMUST00000107864.1
transmembrane protein 8B
chr14_-_105896819 0.32 ENSMUST00000022709.4
sprouty homolog 2 (Drosophila)
chr1_+_135146782 0.31 ENSMUST00000027684.4
ADP-ribosylation factor-like 8A
chr2_+_156008045 0.31 ENSMUST00000006035.6
ERGIC and golgi 3
chr7_+_19176416 0.31 ENSMUST00000117338.1
echinoderm microtubule associated protein like 2
chr2_+_156008088 0.31 ENSMUST00000088650.4
ERGIC and golgi 3
chr2_+_152293828 0.31 ENSMUST00000028963.7
ENSMUST00000144252.1
TBC1 domain family, member 20
chr11_-_98053415 0.31 ENSMUST00000017544.2
SH3 and cysteine rich domain 2
chr2_+_6322621 0.31 ENSMUST00000114937.1
USP6 N-terminal like
chr11_+_104231390 0.31 ENSMUST00000106992.3
microtubule-associated protein tau
chr19_+_56722372 0.30 ENSMUST00000038949.4
adrenergic receptor, beta 1
chr12_-_72408934 0.30 ENSMUST00000078505.7
reticulon 1
chr7_+_99381495 0.30 ENSMUST00000037528.8
glycerophosphodiester phosphodiesterase domain containing 5
chr1_-_156035891 0.30 ENSMUST00000126448.1
torsin A interacting protein 1
chr4_+_129985098 0.29 ENSMUST00000106017.1
ENSMUST00000121049.1
brain-specific angiogenesis inhibitor 2
chr16_+_17797282 0.29 ENSMUST00000012161.3
scavenger receptor class F, member 2
chr2_-_180954620 0.29 ENSMUST00000139929.1
Na+/K+ transporting ATPase interacting 4
chr5_+_130222328 0.29 ENSMUST00000111298.4
transmembrane protein 248
chr17_+_44188564 0.29 ENSMUST00000024755.5
chloride intracellular channel 5
chr7_-_126082406 0.28 ENSMUST00000073935.5
GSG1-like
chr4_-_43669141 0.28 ENSMUST00000056474.6
family with sequence similarity 221, member B
chr8_+_127064022 0.28 ENSMUST00000160272.1
ENSMUST00000079777.5
ENSMUST00000162907.1
par-3 (partitioning defective 3) homolog (C. elegans)
chr8_-_90348343 0.27 ENSMUST00000109621.3
TOX high mobility group box family member 3
chr4_-_55532453 0.27 ENSMUST00000132746.1
ENSMUST00000107619.2
Kruppel-like factor 4 (gut)
chr18_-_80713062 0.27 ENSMUST00000170905.1
ENSMUST00000078049.4
nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1
chr1_+_75375271 0.26 ENSMUST00000087122.5
SPEG complex locus
chr3_-_117868821 0.26 ENSMUST00000167877.1
ENSMUST00000169812.1
sorting nexin 7
chrX_+_152144240 0.26 ENSMUST00000168786.1
ENSMUST00000112605.1
ENSMUST00000112604.1
IQ motif and Sec7 domain 2
chr12_+_35047180 0.26 ENSMUST00000048519.9
ENSMUST00000163677.1
sorting nexin 13
chr17_+_46681038 0.26 ENSMUST00000002845.6
male enhanced antigen 1
chr18_-_6490808 0.25 ENSMUST00000028100.6
ENSMUST00000050542.5
enhancer of polycomb homolog 1 (Drosophila)
chr15_-_103366763 0.25 ENSMUST00000023128.6
integrin alpha 5 (fibronectin receptor alpha)
chr11_-_96829483 0.25 ENSMUST00000167149.1
nuclear factor, erythroid derived 2,-like 1
chr10_-_80742211 0.25 ENSMUST00000020420.7
adaptor-related protein complex 3, delta 1 subunit
chr3_-_89773221 0.25 ENSMUST00000038450.1
RIKEN cDNA 4632404H12 gene
chr7_-_5038427 0.25 ENSMUST00000062428.4
zinc finger protein 784
chr15_+_74563738 0.25 ENSMUST00000170845.1
brain-specific angiogenesis inhibitor 1
chr11_-_50292302 0.25 ENSMUST00000059458.4
mastermind like 1 (Drosophila)
chr4_+_43669610 0.24 ENSMUST00000107866.1
transmembrane protein 8B
chr17_+_68837062 0.24 ENSMUST00000178545.1
transmembrane protein 200C
chr11_+_32642826 0.24 ENSMUST00000093205.6
ENSMUST00000076383.7
F-box and WD-40 domain protein 11
chr8_+_20550331 0.24 ENSMUST00000178451.1
predicted gene, 21092
chr17_-_29237759 0.24 ENSMUST00000137727.1
ENSMUST00000024805.7
copine V
chr4_-_139380374 0.24 ENSMUST00000181556.1
RIKEN cDNA 2700016F22 gene
chr1_-_36558214 0.24 ENSMUST00000154493.1
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4C
chr11_-_121354337 0.24 ENSMUST00000106110.3
ENSMUST00000136797.1
ENSMUST00000026173.6
WD repeat domain 45B
chr15_-_97831460 0.23 ENSMUST00000079838.7
ENSMUST00000118294.1
histone deacetylase 7
chr18_-_25168615 0.23 ENSMUST00000148255.1
tubulin polyglutamylase complex subunit 2
chr8_-_87959560 0.23 ENSMUST00000109655.2
zinc finger protein 423
chr19_-_4397052 0.23 ENSMUST00000075856.4
lysine (K)-specific demethylase 2A
chr9_+_61373219 0.23 ENSMUST00000162583.1
ENSMUST00000161993.1
ENSMUST00000160882.1
ENSMUST00000160724.1
ENSMUST00000162973.1
ENSMUST00000159050.1
transducin-like enhancer of split 3, homolog of Drosophila E(spl)
chr9_+_61373482 0.23 ENSMUST00000160541.1
ENSMUST00000161207.1
ENSMUST00000159630.1
transducin-like enhancer of split 3, homolog of Drosophila E(spl)
chr8_-_123254169 0.23 ENSMUST00000117643.1
VPS9 domain containing 1
chrX_+_151520655 0.23 ENSMUST00000112666.1
ENSMUST00000168501.1
ENSMUST00000112662.2
PHD finger protein 8
chr6_+_4747306 0.22 ENSMUST00000175823.1
ENSMUST00000176204.1
ENSMUST00000166678.1
paternally expressed 10
chr5_-_113015473 0.22 ENSMUST00000065167.4
adrenergic receptor kinase, beta 2
chr6_+_37870786 0.22 ENSMUST00000120428.1
ENSMUST00000031859.7
tripartite motif-containing 24
chr3_+_89164790 0.22 ENSMUST00000121212.2
ENSMUST00000152205.1
ENSMUST00000090927.5
ENSMUST00000148265.1
ENSMUST00000121931.1
CDC-like kinase 2
chr4_-_133339283 0.22 ENSMUST00000043305.7
WD and tetratricopeptide repeats 1
chr12_+_24572276 0.21 ENSMUST00000085553.5
grainyhead-like 1 (Drosophila)
chr2_-_152831665 0.21 ENSMUST00000156688.1
ENSMUST00000007803.5
BCL2-like 1
chr9_-_119578981 0.21 ENSMUST00000117911.1
ENSMUST00000120420.1
sodium channel, voltage-gated, type V, alpha
chr6_-_53820764 0.21 ENSMUST00000127748.2
TLR4 interactor with leucine-rich repeats
chr5_-_115272883 0.21 ENSMUST00000040555.8
ENSMUST00000112096.2
ENSMUST00000112097.1
ring finger protein 10
chr11_+_32642706 0.21 ENSMUST00000109366.1
F-box and WD-40 domain protein 11
chr4_-_155734627 0.21 ENSMUST00000178987.1
RIKEN cDNA 1500002C15 gene
chr9_-_121277160 0.21 ENSMUST00000051479.6
ENSMUST00000171923.1
unc-51-like kinase 4
chr7_-_45366714 0.20 ENSMUST00000107779.1
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 3
chr1_+_172148015 0.20 ENSMUST00000074144.5
DDB1 and CUL4 associated factor 8
chr1_+_91801453 0.20 ENSMUST00000007949.3
twist basic helix-loop-helix transcription factor 2
chr17_-_24895047 0.20 ENSMUST00000119848.1
ENSMUST00000121542.1
essential meiotic endonuclease 1 homolog 2 (S. pombe)
chr6_+_47454320 0.20 ENSMUST00000031697.8
cullin 1
chr15_+_97784355 0.20 ENSMUST00000117892.1
solute carrier family 48 (heme transporter), member 1
chr4_-_133339238 0.20 ENSMUST00000105906.1
WD and tetratricopeptide repeats 1
chr12_-_85339346 0.19 ENSMUST00000040992.7
NIMA (never in mitosis gene a)-related expressed kinase 9
chr10_-_8886033 0.19 ENSMUST00000015449.5
SAM and SH3 domain containing 1
chr19_-_36057340 0.19 ENSMUST00000164639.1
ENSMUST00000166074.1
ENSMUST00000099505.3
5-hydroxytryptamine (serotonin) receptor 7
chr19_+_9982694 0.19 ENSMUST00000025563.6
ferritin heavy chain 1
chr9_+_61373608 0.19 ENSMUST00000161689.1
transducin-like enhancer of split 3, homolog of Drosophila E(spl)
chr12_-_108179237 0.19 ENSMUST00000071095.7
SET domain containing 3
chr16_-_20426375 0.19 ENSMUST00000079158.6
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
chr19_+_10525244 0.18 ENSMUST00000038379.3
cleavage and polyadenylation specific factor 7
chr9_-_20976762 0.18 ENSMUST00000054197.5
sphingosine-1-phosphate receptor 2
chr8_+_27085520 0.18 ENSMUST00000178514.1
ENSMUST00000033876.7
G protein-coupled receptor 124
chr18_+_76241580 0.18 ENSMUST00000168423.1
ENSMUST00000091831.6
SMAD family member 2
chr3_+_28781305 0.18 ENSMUST00000060500.7
eukaryotic translation initiation factor 5A2
chr11_+_49244191 0.18 ENSMUST00000167400.1
ENSMUST00000081794.6
mannoside acetylglucosaminyltransferase 1
chr2_+_48814109 0.18 ENSMUST00000063886.3
activin receptor IIA
chr5_+_64803513 0.18 ENSMUST00000165536.1
Kruppel-like factor 3 (basic)
chr15_-_53346118 0.17 ENSMUST00000077273.2
exostoses (multiple) 1
chr5_-_122988533 0.17 ENSMUST00000086200.4
ENSMUST00000156474.1
lysine (K)-specific demethylase 2B
chr17_-_87265866 0.17 ENSMUST00000145895.1
ENSMUST00000129616.1
ENSMUST00000155904.1
ENSMUST00000151155.1
ENSMUST00000144236.1
ENSMUST00000024963.3
multiple coagulation factor deficiency 2
chr7_-_120982260 0.17 ENSMUST00000033169.8
cerebellar degeneration-related 2
chr17_+_24895116 0.16 ENSMUST00000043907.7
mitochondrial ribosomal protein S34
chr4_-_151861667 0.16 ENSMUST00000169423.2
calmodulin binding transcription activator 1
chr19_-_47464406 0.16 ENSMUST00000111800.2
ENSMUST00000081619.2
SH3 and PX domains 2A
chr17_-_46680870 0.16 ENSMUST00000165007.1
ENSMUST00000071841.5
kelch domain containing 3
chr9_+_80165013 0.16 ENSMUST00000035889.8
ENSMUST00000113268.1
myosin VI
chr16_-_10543028 0.16 ENSMUST00000184863.1
ENSMUST00000038281.5
dexamethasone-induced transcript
chr11_-_106920681 0.16 ENSMUST00000103067.3
SMAD specific E3 ubiquitin protein ligase 2
chr16_-_18629864 0.16 ENSMUST00000096987.5
septin 5
chr5_+_53998417 0.16 ENSMUST00000117661.2
ENSMUST00000071083.7
stromal interaction molecule 2
chr18_+_70568189 0.16 ENSMUST00000074058.4
ENSMUST00000114946.3
methyl-CpG binding domain protein 2
chr5_-_39644597 0.16 ENSMUST00000152057.1
heparan sulfate (glucosamine) 3-O-sulfotransferase 1
chr1_+_74391479 0.15 ENSMUST00000027367.7
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
chr2_+_117121374 0.15 ENSMUST00000028829.6
sprouty protein with EVH-1 domain 1, related sequence
chr15_+_89429560 0.15 ENSMUST00000168646.1
RIKEN cDNA C730034F03 gene
chr19_+_6241668 0.14 ENSMUST00000045351.6
autophagy related 2A
chr7_+_30231884 0.14 ENSMUST00000019882.9
polymerase (RNA) II (DNA directed) polypeptide I
chr4_+_155734800 0.14 ENSMUST00000147721.1
ENSMUST00000127188.2
transmembrane protein 240
chr17_-_47924460 0.14 ENSMUST00000113262.1
forkhead box P4
chr6_-_72899952 0.14 ENSMUST00000068697.8
potassium channel modulatory factor 1
chr11_+_104231573 0.14 ENSMUST00000132977.1
ENSMUST00000132245.1
ENSMUST00000100347.4
microtubule-associated protein tau
chr7_-_102250086 0.14 ENSMUST00000106923.1
ENSMUST00000098230.4
ras homolog gene family, member G

Network of associatons between targets according to the STRING database.

First level regulatory network of Mbd2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.2 GO:0072162 tertiary branching involved in mammary gland duct morphogenesis(GO:0060748) renal vesicle induction(GO:0072034) metanephric mesenchymal cell differentiation(GO:0072162) negative regulation of male gonad development(GO:2000019)
0.4 1.1 GO:0046022 regulation of transcription from RNA polymerase II promoter, mitotic(GO:0046021) positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022)
0.3 0.3 GO:0045896 regulation of transcription during mitosis(GO:0045896) positive regulation of transcription during mitosis(GO:0045897)
0.3 0.9 GO:0007521 muscle cell fate determination(GO:0007521)
0.3 1.0 GO:0007228 positive regulation of hh target transcription factor activity(GO:0007228)
0.2 0.5 GO:0016539 intein-mediated protein splicing(GO:0016539) protein splicing(GO:0030908)
0.2 0.7 GO:0060300 regulation of cytokine activity(GO:0060300)
0.2 1.0 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.2 1.2 GO:0008291 acetylcholine metabolic process(GO:0008291) acetate ester metabolic process(GO:1900619)
0.2 0.8 GO:0030222 eosinophil differentiation(GO:0030222)
0.2 0.7 GO:0021586 pons maturation(GO:0021586)
0.2 1.8 GO:0023041 neuronal signal transduction(GO:0023041)
0.1 1.9 GO:0030322 stabilization of membrane potential(GO:0030322)
0.1 0.5 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.1 0.4 GO:0006714 sesquiterpenoid metabolic process(GO:0006714)
0.1 0.6 GO:0021914 negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
0.1 0.7 GO:0003383 apical constriction(GO:0003383)
0.1 0.7 GO:0042997 negative regulation of Golgi to plasma membrane protein transport(GO:0042997) negative regulation of establishment of protein localization to plasma membrane(GO:0090005)
0.1 0.3 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.1 0.3 GO:0001997 positive regulation of the force of heart contraction by epinephrine-norepinephrine(GO:0001997) positive regulation of the force of heart contraction by chemical signal(GO:0003099) positive regulation of renin secretion into blood stream(GO:1900135)
0.1 0.3 GO:0035574 histone H4-K20 demethylation(GO:0035574)
0.1 0.4 GO:0032227 negative regulation of synaptic transmission, dopaminergic(GO:0032227)
0.1 0.6 GO:0036466 synaptic vesicle recycling via endosome(GO:0036466)
0.1 0.5 GO:0060849 regulation of transcription involved in lymphatic endothelial cell fate commitment(GO:0060849)
0.1 0.3 GO:0045415 negative regulation of interleukin-8 biosynthetic process(GO:0045415)
0.1 0.3 GO:0060854 patterning of lymph vessels(GO:0060854)
0.1 0.8 GO:0051611 regulation of serotonin uptake(GO:0051611)
0.1 0.2 GO:0003162 atrioventricular node development(GO:0003162)
0.1 0.2 GO:0001192 maintenance of transcriptional fidelity during DNA-templated transcription elongation(GO:0001192) maintenance of transcriptional fidelity during DNA-templated transcription elongation from RNA polymerase II promoter(GO:0001193)
0.1 0.7 GO:1900034 regulation of cellular response to heat(GO:1900034)
0.1 0.4 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.1 0.4 GO:1902897 regulation of postsynaptic density protein 95 clustering(GO:1902897)
0.1 0.3 GO:0071694 protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694)
0.1 1.8 GO:0095500 acetylcholine receptor signaling pathway(GO:0095500) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
0.1 0.2 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.1 0.2 GO:0051385 response to mineralocorticoid(GO:0051385)
0.1 0.4 GO:0016266 O-glycan processing(GO:0016266)
0.1 0.2 GO:0046881 positive regulation of follicle-stimulating hormone secretion(GO:0046881)
0.1 0.3 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.1 0.4 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.1 0.3 GO:0051387 negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.1 0.7 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.1 0.4 GO:0071896 protein localization to adherens junction(GO:0071896)
0.1 0.3 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.0 0.2 GO:0015886 heme transport(GO:0015886)
0.0 0.2 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.0 0.3 GO:0010968 regulation of microtubule nucleation(GO:0010968)
0.0 0.1 GO:1900175 zygotic specification of dorsal/ventral axis(GO:0007352) regulation of nodal signaling pathway involved in determination of left/right asymmetry(GO:1900145) regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900175) positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224) positive regulation of mesoderm development(GO:2000382)
0.0 0.2 GO:0021993 initiation of neural tube closure(GO:0021993)
0.0 0.5 GO:0042538 hyperosmotic salinity response(GO:0042538)
0.0 0.1 GO:1904100 regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
0.0 0.1 GO:2001160 regulation of histone H3-K79 methylation(GO:2001160)
0.0 0.1 GO:0006114 glycerol biosynthetic process(GO:0006114)
0.0 0.2 GO:0010626 negative regulation of Schwann cell proliferation(GO:0010626)
0.0 0.1 GO:2000742 anterior head development(GO:0097065) regulation of anterior head development(GO:2000742) positive regulation of anterior head development(GO:2000744)
0.0 0.1 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.0 0.3 GO:0070862 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.0 0.1 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.0 0.3 GO:0071763 nuclear membrane organization(GO:0071763)
0.0 0.1 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.2 GO:0032237 activation of store-operated calcium channel activity(GO:0032237)
0.0 0.2 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.0 0.2 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.0 0.2 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.0 0.2 GO:0033184 positive regulation of histone ubiquitination(GO:0033184)
0.0 0.8 GO:0016578 histone deubiquitination(GO:0016578)
0.0 0.6 GO:0007263 nitric oxide mediated signal transduction(GO:0007263)
0.0 0.2 GO:0072675 osteoclast fusion(GO:0072675)
0.0 0.2 GO:1903142 sphingosine-1-phosphate signaling pathway(GO:0003376) positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.0 0.1 GO:2001287 negative regulation of caveolin-mediated endocytosis(GO:2001287)
0.0 0.4 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.0 0.4 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.3 GO:1901250 regulation of lung goblet cell differentiation(GO:1901249) negative regulation of lung goblet cell differentiation(GO:1901250)
0.0 0.1 GO:2001137 positive regulation of endocytic recycling(GO:2001137)
0.0 0.4 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.0 0.1 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.0 0.4 GO:2000035 regulation of stem cell division(GO:2000035)
0.0 0.1 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.0 0.1 GO:1905051 regulation of base-excision repair(GO:1905051) positive regulation of base-excision repair(GO:1905053)
0.0 0.1 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.0 0.3 GO:0002024 diet induced thermogenesis(GO:0002024)
0.0 0.2 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.0 0.1 GO:0060596 mammary placode formation(GO:0060596)
0.0 0.1 GO:0003032 detection of oxygen(GO:0003032) cell migration involved in endocardial cushion formation(GO:0003273) cardiac jelly development(GO:1905072)
0.0 0.5 GO:0042347 negative regulation of NF-kappaB import into nucleus(GO:0042347)
0.0 0.1 GO:1900095 regulation of dosage compensation by inactivation of X chromosome(GO:1900095)
0.0 0.1 GO:0072362 regulation of glycolytic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072362)
0.0 0.2 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
0.0 0.2 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.2 GO:0002934 desmosome organization(GO:0002934)
0.0 0.1 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.0 0.3 GO:1900454 positive regulation of long term synaptic depression(GO:1900454)
0.0 0.4 GO:0044804 nucleophagy(GO:0044804)
0.0 0.1 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.1 GO:0001887 selenium compound metabolic process(GO:0001887) selenocysteine metabolic process(GO:0016259)
0.0 0.2 GO:0010838 positive regulation of keratinocyte proliferation(GO:0010838)
0.0 0.1 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.0 0.1 GO:0006646 phosphatidylethanolamine biosynthetic process(GO:0006646)
0.0 0.1 GO:0021960 anterior commissure morphogenesis(GO:0021960)
0.0 0.5 GO:0071353 cellular response to interleukin-4(GO:0071353)
0.0 0.2 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.0 0.3 GO:0071577 zinc II ion transmembrane transport(GO:0071577)
0.0 0.1 GO:0055099 response to high density lipoprotein particle(GO:0055099)
0.0 0.1 GO:2001184 positive regulation of interleukin-12 secretion(GO:2001184)
0.0 0.3 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.3 GO:0021895 cerebral cortex neuron differentiation(GO:0021895)
0.0 0.4 GO:0035767 endothelial cell chemotaxis(GO:0035767)
0.0 0.1 GO:0060178 regulation of exocyst localization(GO:0060178)
0.0 0.1 GO:0060689 cell differentiation involved in salivary gland development(GO:0060689)
0.0 1.2 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 0.2 GO:0071257 cellular response to electrical stimulus(GO:0071257)
0.0 0.2 GO:0048172 regulation of short-term neuronal synaptic plasticity(GO:0048172)
0.0 0.4 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.1 GO:0060836 lymphatic endothelial cell differentiation(GO:0060836)
0.0 0.0 GO:0061386 closure of optic fissure(GO:0061386)
0.0 0.1 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.2 GO:0022038 corpus callosum development(GO:0022038)
0.0 0.7 GO:0016925 protein sumoylation(GO:0016925)
0.0 0.2 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.0 0.4 GO:0035774 positive regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0035774)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0016533 cyclin-dependent protein kinase 5 holoenzyme complex(GO:0016533)
0.2 1.4 GO:0016012 sarcoglycan complex(GO:0016012)
0.1 0.4 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.1 1.2 GO:0043083 synaptic cleft(GO:0043083)
0.1 0.7 GO:0033269 internode region of axon(GO:0033269)
0.1 0.2 GO:0098830 presynaptic endosome(GO:0098830)
0.1 0.7 GO:0045298 tubulin complex(GO:0045298)
0.1 0.2 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.1 0.4 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.1 0.3 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.2 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.8 GO:0000124 SAGA complex(GO:0000124)
0.0 0.2 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.8 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.2 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.0 1.6 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.1 GO:0020018 ciliary pocket(GO:0020016) ciliary pocket membrane(GO:0020018)
0.0 0.2 GO:0005726 perichromatin fibrils(GO:0005726)
0.0 0.4 GO:0016342 catenin complex(GO:0016342)
0.0 0.2 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.1 GO:0030905 retromer, tubulation complex(GO:0030905)
0.0 0.3 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.1 GO:0071144 activin responsive factor complex(GO:0032444) SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.3 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.3 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.3 GO:0032279 asymmetric synapse(GO:0032279)
0.0 0.5 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.0 0.2 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.3 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.7 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.1 GO:0061574 ASAP complex(GO:0061574)
0.0 0.2 GO:0044754 autolysosome(GO:0044754)
0.0 0.2 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.4 GO:0051233 spindle midzone(GO:0051233)
0.0 0.2 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.0 0.3 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.0 GO:1990730 VCP-NSFL1C complex(GO:1990730)
0.0 0.2 GO:0031105 septin complex(GO:0031105)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.2 GO:0004104 cholinesterase activity(GO:0004104)
0.2 0.7 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.2 1.4 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.1 1.9 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.1 0.6 GO:0034056 estrogen response element binding(GO:0034056)
0.1 0.3 GO:0051380 norepinephrine binding(GO:0051380)
0.1 0.3 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.1 0.7 GO:0099609 microtubule lateral binding(GO:0099609)
0.1 0.3 GO:0001225 RNA polymerase II transcription coactivator binding(GO:0001225)
0.1 0.3 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739)
0.1 0.6 GO:0045545 syndecan binding(GO:0045545)
0.1 0.3 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.1 0.5 GO:0005113 patched binding(GO:0005113)
0.1 0.4 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.1 1.0 GO:0070742 C2H2 zinc finger domain binding(GO:0070742)
0.1 0.4 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.1 0.2 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.1 0.3 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.0 0.4 GO:0043559 insulin binding(GO:0043559)
0.0 0.2 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.2 GO:0045322 unmethylated CpG binding(GO:0045322)
0.0 0.2 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.0 2.8 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 1.8 GO:0005109 frizzled binding(GO:0005109)
0.0 0.3 GO:0017002 activin-activated receptor activity(GO:0017002)
0.0 0.9 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.1 GO:0004103 choline kinase activity(GO:0004103)
0.0 0.2 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.0 0.3 GO:0051434 BH3 domain binding(GO:0051434)
0.0 1.0 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.1 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.1 GO:0097003 adipokinetic hormone receptor activity(GO:0097003)
0.0 0.2 GO:0086006 voltage-gated sodium channel activity involved in cardiac muscle cell action potential(GO:0086006)
0.0 0.1 GO:0008967 phosphoglycolate phosphatase activity(GO:0008967)
0.0 0.5 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.4 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.2 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.1 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 0.2 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 0.2 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.1 GO:1990460 leptin receptor binding(GO:1990460)
0.0 0.1 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.0 0.7 GO:0019789 SUMO transferase activity(GO:0019789)
0.0 0.6 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.4 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.1 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.3 GO:0004579 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 1.5 GO:0005546 phosphatidylinositol-4,5-bisphosphate binding(GO:0005546)
0.0 1.0 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.2 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.1 GO:0047288 monosialoganglioside sialyltransferase activity(GO:0047288)
0.0 0.4 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 0.3 GO:0005537 mannose binding(GO:0005537)
0.0 0.1 GO:0070279 vitamin B6 binding(GO:0070279)
0.0 0.1 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.1 GO:0005072 transforming growth factor beta receptor, cytoplasmic mediator activity(GO:0005072)
0.0 0.2 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993) serotonin binding(GO:0051378)
0.0 0.1 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.0 1.5 GO:0008013 beta-catenin binding(GO:0008013)
0.0 0.2 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.0 0.4 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.2 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.2 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.1 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.0 0.3 GO:0005521 lamin binding(GO:0005521)
0.0 0.1 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.4 GO:0031683 G-protein beta/gamma-subunit complex binding(GO:0031683)
0.0 0.2 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 0.6 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 0.1 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.0 0.3 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.1 GO:0050733 RS domain binding(GO:0050733)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 0.4 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 2.8 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 0.6 PID S1P S1P2 PATHWAY S1P2 pathway
0.0 0.7 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.9 PID BMP PATHWAY BMP receptor signaling
0.0 1.3 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.3 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.7 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.2 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 0.3 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.6 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.3 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 0.4 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.3 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.4 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.5 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 0.6 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.4 PID HNF3A PATHWAY FOXA1 transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.9 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 1.1 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.7 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.5 REACTOME ADENYLATE CYCLASE INHIBITORY PATHWAY Genes involved in Adenylate cyclase inhibitory pathway
0.0 2.6 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.7 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.6 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.1 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.3 REACTOME SPRY REGULATION OF FGF SIGNALING Genes involved in Spry regulation of FGF signaling
0.0 1.3 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.2 REACTOME SEROTONIN RECEPTORS Genes involved in Serotonin receptors
0.0 0.3 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.0 0.3 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.8 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.3 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.8 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.2 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 0.3 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 0.4 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.4 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.4 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 0.2 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.1 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle