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2D miR_HR1_12

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Results for Hnf4a

Z-value: 2.48

Motif logo

Transcription factors associated with Hnf4a

Gene Symbol Gene ID Gene Info
ENSMUSG00000017950.10 hepatic nuclear factor 4, alpha

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Hnf4amm10_v2_chr2_+_163547148_163547188-0.623.2e-02Click!

Activity profile of Hnf4a motif

Sorted Z-values of Hnf4a motif

Promoter Log-likelihood Transcript Gene Gene Info
chr3_+_122895072 8.26 ENSMUST00000023820.5
fatty acid binding protein 2, intestinal
chr9_+_46240696 4.66 ENSMUST00000034585.6
apolipoprotein A-IV
chr18_+_21072329 4.45 ENSMUST00000082235.4
meprin 1 beta
chr2_+_174760619 3.55 ENSMUST00000029030.2
endothelin 3
chr4_+_118527229 3.51 ENSMUST00000030261.5
RIKEN cDNA 2610528J11 gene
chr1_-_87101590 3.37 ENSMUST00000113270.2
alkaline phosphatase, intestinal
chr15_-_78855517 3.30 ENSMUST00000044584.4
lectin, galactose-binding, soluble 2
chr11_-_3931960 3.20 ENSMUST00000109990.1
ENSMUST00000020710.4
ENSMUST00000109989.3
ENSMUST00000109991.1
ENSMUST00000109993.2
transcobalamin 2
chr11_-_3931789 2.97 ENSMUST00000109992.1
ENSMUST00000109988.1
transcobalamin 2
chr6_+_71199827 2.80 ENSMUST00000067492.7
fatty acid binding protein 1, liver
chr3_+_60031754 2.68 ENSMUST00000029325.3
arylacetamide deacetylase (esterase)
chr2_+_174760781 2.66 ENSMUST00000140908.1
endothelin 3
chr16_+_33794008 2.64 ENSMUST00000115044.1
mucin 13, epithelial transmembrane
chr9_+_44673227 2.57 ENSMUST00000034609.4
ENSMUST00000071219.5
trehalase (brush-border membrane glycoprotein)
chr16_+_33794345 2.54 ENSMUST00000023520.6
mucin 13, epithelial transmembrane
chr2_+_173153048 2.46 ENSMUST00000029017.5
phosphoenolpyruvate carboxykinase 1, cytosolic
chr8_-_113848615 2.45 ENSMUST00000093113.4
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 18
chr11_+_115877497 2.38 ENSMUST00000144032.1
myosin XVB
chr12_+_7977640 2.37 ENSMUST00000171271.1
ENSMUST00000037811.6
ENSMUST00000037520.7
apolipoprotein B
chr15_+_102150502 2.36 ENSMUST00000023806.6
sterol O-acyltransferase 2
chr9_+_107975529 2.35 ENSMUST00000035216.4
ubiquitin-like modifier activating enzyme 7
chr19_+_39060998 2.28 ENSMUST00000087236.4
cytochrome P450, family 2, subfamily c, polypeptide 65
chr4_+_118526986 2.27 ENSMUST00000106367.1
RIKEN cDNA 2610528J11 gene
chr17_+_34377124 2.25 ENSMUST00000080254.5
butyrophilin-like 1
chr11_+_101367542 2.24 ENSMUST00000019469.2
glucose-6-phosphatase, catalytic
chr16_-_30310773 2.23 ENSMUST00000061190.6
glycoprotein 5 (platelet)
chr15_-_82794236 2.20 ENSMUST00000006094.4
cytochrome P450, family 2, subfamily d, polypeptide 26
chr7_+_29170345 2.13 ENSMUST00000033886.7
gametogenetin
chr15_+_10358525 2.12 ENSMUST00000110540.1
ENSMUST00000110541.1
ENSMUST00000110542.1
alanine-glyoxylate aminotransferase 2
chr15_+_10358556 2.12 ENSMUST00000022858.7
alanine-glyoxylate aminotransferase 2
chr11_+_70505244 2.09 ENSMUST00000019063.2
transmembrane 4 superfamily member 5
chr6_-_41636389 2.08 ENSMUST00000031902.5
transient receptor potential cation channel, subfamily V, member 6
chr7_+_29170204 2.07 ENSMUST00000098609.2
gametogenetin
chr2_-_25500613 2.04 ENSMUST00000040042.4
complement component 8, gamma polypeptide
chr15_+_99099412 2.03 ENSMUST00000061295.6
DnaJ (Hsp40) homolog, subfamily C, member 22
chr7_-_19676749 1.88 ENSMUST00000003074.9
apolipoprotein C-II
chr6_-_65144908 1.88 ENSMUST00000031982.4
hematopoietic prostaglandin D synthase
chr4_+_110397661 1.86 ENSMUST00000106589.2
ENSMUST00000106587.2
ENSMUST00000106591.1
ENSMUST00000106592.1
ATP/GTP binding protein-like 4
chr5_-_103977360 1.82 ENSMUST00000048118.8
hydroxysteroid (17-beta) dehydrogenase 13
chr12_+_58211772 1.76 ENSMUST00000110671.2
ENSMUST00000044299.2
somatostatin receptor 1
chr7_+_30493622 1.71 ENSMUST00000058280.6
ENSMUST00000133318.1
ENSMUST00000142575.1
ENSMUST00000131040.1
proline dehydrogenase (oxidase) 2
chr17_+_36898110 1.69 ENSMUST00000078438.4
tripartite motif-containing 31
chr7_+_143473736 1.66 ENSMUST00000052348.5
solute carrier family 22 (organic cation transporter), member 18
chr4_+_120854786 1.66 ENSMUST00000071093.2
regulating synaptic membrane exocytosis 3
chr17_-_35909626 1.63 ENSMUST00000141132.1
alpha tubulin acetyltransferase 1
chr1_-_136234113 1.62 ENSMUST00000120339.1
ENSMUST00000048668.8
RIKEN cDNA 5730559C18 gene
chr17_+_6705830 1.62 ENSMUST00000159880.1
synaptotagmin-like 3
chr4_-_126163470 1.61 ENSMUST00000097891.3
SH3 domain containing 21
chr16_-_22439719 1.60 ENSMUST00000079601.6
ets variant gene 5
chr19_-_39740999 1.59 ENSMUST00000099472.3
cytochrome P450, family 2, subfamily c, polypeptide 68
chr17_-_35910032 1.56 ENSMUST00000141662.1
ENSMUST00000056034.6
ENSMUST00000077494.6
ENSMUST00000149277.1
ENSMUST00000061052.5
alpha tubulin acetyltransferase 1
chr3_-_121815212 1.54 ENSMUST00000029770.5
ATP-binding cassette, sub-family D (ALD), member 3
chr18_+_69925466 1.54 ENSMUST00000043929.4
coiled-coil domain containing 68
chr18_+_69925542 1.52 ENSMUST00000080050.5
coiled-coil domain containing 68
chr16_-_45654083 1.50 ENSMUST00000036732.7
cDNA sequence, BC016579
chr7_-_45759527 1.49 ENSMUST00000075571.7
sulfotransferase family, cytosolic, 2B, member 1
chr12_+_109544498 1.45 ENSMUST00000126289.1
maternally expressed 3
chr4_+_41762309 1.44 ENSMUST00000108042.2
interleukin 11 receptor, alpha chain 1
chr2_-_59160644 1.43 ENSMUST00000077687.5
coiled-coil domain containing 148
chr8_-_71701796 1.43 ENSMUST00000034260.7
UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 3
chr2_-_77170592 1.43 ENSMUST00000164114.2
ENSMUST00000049544.7
coiled-coil domain containing 141
chr5_-_103977404 1.36 ENSMUST00000112803.2
hydroxysteroid (17-beta) dehydrogenase 13
chr4_+_110397764 1.35 ENSMUST00000097920.2
ENSMUST00000080744.6
ATP/GTP binding protein-like 4
chr11_-_3504766 1.35 ENSMUST00000044507.5
inositol polyphosphate 5-phosphatase J
chr6_+_125145235 1.34 ENSMUST00000119527.1
ENSMUST00000088276.6
ENSMUST00000051171.7
ENSMUST00000117675.1
intermediate filament family orphan 1
chr6_+_83156401 1.32 ENSMUST00000032106.4
RIKEN cDNA 1700003E16 gene
chr6_-_125380793 1.32 ENSMUST00000042647.6
pleckstrin homology domain containing, family G (with RhoGef domain) member 6
chr9_-_110989611 1.32 ENSMUST00000084922.5
receptor transporter protein 3
chr5_-_103977326 1.31 ENSMUST00000120320.1
hydroxysteroid (17-beta) dehydrogenase 13
chr15_-_102722120 1.29 ENSMUST00000171838.1
calcium binding and coiled coil domain 1
chr19_+_5088534 1.28 ENSMUST00000025811.4
Yip1 interacting factor homolog A (S. cerevisiae)
chr5_-_24447587 1.28 ENSMUST00000127194.1
ENSMUST00000115033.1
ENSMUST00000123167.1
ENSMUST00000030799.8
transmembrane and ubiquitin-like domain containing 1
chr7_+_28833975 1.28 ENSMUST00000066723.8
lectin, galactose binding, soluble 4
chr9_-_22002599 1.27 ENSMUST00000115336.2
ENSMUST00000044926.5
coiled-coil domain containing 151
chr2_-_119229849 1.26 ENSMUST00000110820.2
protein phosphatase 1, regulatory (inhibitor) subunit 14D
chr6_-_122602345 1.25 ENSMUST00000147760.1
ENSMUST00000112585.1
apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1
chr6_-_122602404 1.25 ENSMUST00000112586.1
apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1
chr3_+_118562129 1.22 ENSMUST00000039177.7
dihydropyrimidine dehydrogenase
chr4_+_152199805 1.21 ENSMUST00000105652.2
acyl-CoA thioesterase 7
chr7_-_19950729 1.20 ENSMUST00000043440.6
immunoglobulin superfamily, member 23
chr4_+_141746672 1.20 ENSMUST00000038161.4
agmatine ureohydrolase (agmatinase)
chr5_+_117120120 1.20 ENSMUST00000111978.1
TAO kinase 3
chr7_+_112953955 1.20 ENSMUST00000182858.1
Ras association (RalGDS/AF-6) domain family (N-terminal) member 10
chr11_-_61267177 1.18 ENSMUST00000066277.3
ENSMUST00000074127.7
ENSMUST00000108715.2
aldehyde dehydrogenase family 3, subfamily A2
chr17_-_91088726 1.16 ENSMUST00000072671.7
ENSMUST00000174331.1
ENSMUST00000161402.3
ENSMUST00000054059.8
neurexin I
chr5_+_19907502 1.15 ENSMUST00000101558.3
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr7_+_46847128 1.14 ENSMUST00000005051.4
lactate dehydrogenase A
chr15_-_102722150 1.14 ENSMUST00000023818.3
calcium binding and coiled coil domain 1
chrX_+_48623737 1.11 ENSMUST00000114936.1
solute carrier family 25 (mitochondrial carrier, brain), member 14
chr18_-_32036941 1.11 ENSMUST00000134663.1
myosin VIIB
chr2_-_27248335 1.11 ENSMUST00000139312.1
sarcosine dehydrogenase
chr12_+_59131286 1.11 ENSMUST00000176464.1
ENSMUST00000170992.2
ENSMUST00000176322.1
CTAGE family, member 5
chr2_-_127729872 1.09 ENSMUST00000028856.2
mal, T cell differentiation protein-like
chr3_+_107877227 1.08 ENSMUST00000037375.8
EPS8-like 3
chr12_+_59131473 1.08 ENSMUST00000177162.1
CTAGE family, member 5
chr5_+_114146525 1.08 ENSMUST00000102582.1
acetyl-Coenzyme A carboxylase beta
chr2_-_119229885 1.07 ENSMUST00000076084.5
protein phosphatase 1, regulatory (inhibitor) subunit 14D
chr19_+_39007019 1.05 ENSMUST00000025966.4
cytochrome P450, family 2, subfamily c, polypeptide 55
chr18_+_63708689 1.05 ENSMUST00000072726.5
WD repeat domain 7
chr5_-_5694559 1.05 ENSMUST00000115426.2
six transmembrane epithelial antigen of prostate 2
chr17_-_28486082 1.04 ENSMUST00000079413.3
FK506 binding protein 5
chr8_-_10928449 1.03 ENSMUST00000040608.3
RIKEN cDNA 3930402G23 gene
chr9_+_22003035 1.01 ENSMUST00000115331.2
ENSMUST00000003493.7
protein kinase C substrate 80K-H
chr19_-_11081088 1.01 ENSMUST00000025636.6
membrane-spanning 4-domains, subfamily A, member 8A
chr1_+_85894281 1.01 ENSMUST00000027425.9
integral membrane protein 2C
chr1_+_88055377 1.01 ENSMUST00000138182.1
ENSMUST00000113142.3
UDP glycosyltransferase 1 family, polypeptide A10
chr9_-_32344237 0.99 ENSMUST00000034533.5
potassium inwardly-rectifying channel, subfamily J, member 5
chr2_+_58755177 0.99 ENSMUST00000102755.3
uridine phosphorylase 2
chr3_-_104818224 0.99 ENSMUST00000002297.5
Moloney leukemia virus 10
chr10_+_70204675 0.98 ENSMUST00000020090.1
RIKEN cDNA 2310015B20 gene
chr9_+_118506226 0.97 ENSMUST00000084820.4
golgi autoantigen, golgin subfamily a, 4
chr3_+_89136133 0.95 ENSMUST00000047111.6
pyruvate kinase liver and red blood cell
chr4_+_126609818 0.94 ENSMUST00000097886.3
ENSMUST00000164362.1
RIKEN cDNA 5730409E04Rik gene
chr4_+_134397380 0.93 ENSMUST00000105870.1
platelet-activating factor acetylhydrolase 2
chr11_+_3895223 0.92 ENSMUST00000055931.4
ENSMUST00000109996.1
dual specificity phosphatase 18
chr19_+_8850785 0.92 ENSMUST00000096257.2
LRRN4 C-terminal like
chr7_+_30459713 0.91 ENSMUST00000006825.8
nephrosis 1, nephrin
chr10_-_127180579 0.91 ENSMUST00000095270.2
solute carrier family 26, member 10
chr11_+_101582236 0.91 ENSMUST00000039581.7
ENSMUST00000100403.2
ENSMUST00000107194.1
ENSMUST00000128614.1
transmembrane protein 106A
chr2_+_58754910 0.90 ENSMUST00000059102.6
uridine phosphorylase 2
chr14_-_63245219 0.88 ENSMUST00000118022.1
ENSMUST00000067417.3
GATA binding protein 4
chr7_-_67222412 0.88 ENSMUST00000181631.1
RIKEN cDNA 1700112J16 gene
chr5_-_5694024 0.86 ENSMUST00000115425.2
ENSMUST00000115427.1
ENSMUST00000115424.2
ENSMUST00000015797.4
six transmembrane epithelial antigen of prostate 2
chr17_+_34604262 0.86 ENSMUST00000174041.1
1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha)
chr5_+_90561102 0.85 ENSMUST00000094615.4
RIKEN cDNA 5830473C10 gene
chrX_-_16817339 0.84 ENSMUST00000040820.6
monoamine oxidase B
chr7_-_99695628 0.83 ENSMUST00000145381.1
solute carrier organic anion transporter family, member 2b1
chr3_-_67463828 0.82 ENSMUST00000058981.2
latexin
chr8_+_13026024 0.82 ENSMUST00000033820.3
coagulation factor VII
chr7_+_25268387 0.82 ENSMUST00000169392.1
capicua homolog (Drosophila)
chr3_-_84304762 0.81 ENSMUST00000107692.1
tripartite motif-containing 2
chr3_-_104818539 0.81 ENSMUST00000106774.1
ENSMUST00000106775.1
ENSMUST00000166979.1
ENSMUST00000136148.1
Moloney leukemia virus 10
chr8_+_13037308 0.81 ENSMUST00000063820.5
ENSMUST00000033821.4
coagulation factor X
chr4_+_131873608 0.81 ENSMUST00000053819.3
serine/arginine-rich splicing factor 4
chr10_-_20724696 0.80 ENSMUST00000170265.1
phosphodiesterase 7B
chr11_+_7197780 0.79 ENSMUST00000020704.7
insulin-like growth factor binding protein 1
chr1_-_24005608 0.79 ENSMUST00000027338.3
RIKEN cDNA 1110058L19 gene
chr19_-_45998479 0.78 ENSMUST00000045396.7
RIKEN cDNA 9130011E15 gene
chr7_-_135528645 0.78 ENSMUST00000053716.7
clarin 3
chr16_-_34095983 0.78 ENSMUST00000114973.1
ENSMUST00000114964.1
kalirin, RhoGEF kinase
chr11_+_58199556 0.76 ENSMUST00000035266.4
ENSMUST00000094169.4
ENSMUST00000168280.1
ENSMUST00000058704.8
interferon gamma induced GTPase
immunity-related GTPase family M member 2
chr11_-_23519181 0.75 ENSMUST00000020527.5
RIKEN cDNA 1700093K21 gene
chr1_-_82768449 0.75 ENSMUST00000027331.2
transmembrane 4 L six family member 20
chr7_-_25615874 0.74 ENSMUST00000098663.1
predicted gene 7092
chr10_-_128744014 0.74 ENSMUST00000026414.7
diacylglycerol kinase, alpha
chr3_+_89136572 0.73 ENSMUST00000107482.3
ENSMUST00000127058.1
pyruvate kinase liver and red blood cell
chr19_+_39113898 0.73 ENSMUST00000087234.2
cytochrome P450, family 2, subfamily c, polypeptide 66
chr12_+_37241729 0.72 ENSMUST00000160768.1
alkylglycerol monooxygenase
chr17_-_46645128 0.72 ENSMUST00000003642.6
kinesin light chain 4
chr2_+_158028481 0.71 ENSMUST00000103123.3
regulation of nuclear pre-mRNA domain containing 1B
chr13_-_64248495 0.71 ENSMUST00000109769.2
CDC14 cell division cycle 14B
chr1_+_88055467 0.71 ENSMUST00000173325.1
UDP glycosyltransferase 1 family, polypeptide A10
chr4_-_111898695 0.70 ENSMUST00000102720.1
solute carrier family 5 (sodium/glucose cotransporter), member 9
chr2_+_158028687 0.69 ENSMUST00000109518.1
ENSMUST00000029180.7
regulation of nuclear pre-mRNA domain containing 1B
chr3_-_10335650 0.68 ENSMUST00000078748.3
solute carrier family 10 (sodium/bile acid cotransporter family), member 5
chr5_-_5694269 0.66 ENSMUST00000148333.1
six transmembrane epithelial antigen of prostate 2
chr12_-_67222549 0.65 ENSMUST00000037181.8
MAM domain containing glycosylphosphatidylinositol anchor 2
chr19_+_46152505 0.65 ENSMUST00000026254.7
golgi-specific brefeldin A-resistance factor 1
chr1_+_193301953 0.64 ENSMUST00000016315.9
laminin, beta 3
chr17_-_34882004 0.64 ENSMUST00000152417.1
ENSMUST00000146299.1
complement component 2 (within H-2S)
predicted gene 20547
chr1_+_178319130 0.63 ENSMUST00000027781.6
COX20 Cox2 chaperone
chr7_-_99695572 0.63 ENSMUST00000137914.1
solute carrier organic anion transporter family, member 2b1
chr7_+_81114816 0.63 ENSMUST00000119083.1
solute carrier family 28 (sodium-coupled nucleoside transporter), member 1
chr4_-_138326234 0.61 ENSMUST00000105817.3
ENSMUST00000030536.6
PTEN induced putative kinase 1
chr11_+_55213783 0.61 ENSMUST00000108867.1
solute carrier family 36 (proton/amino acid symporter), member 1
chr17_-_15826521 0.60 ENSMUST00000170578.1
RGM domain family, member B
chr11_+_119314787 0.60 ENSMUST00000053245.6
caspase recruitment domain family, member 14
chr15_-_100424208 0.60 ENSMUST00000154331.1
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
chr4_-_94650092 0.59 ENSMUST00000107101.1
leucine rich repeat containing 19
chr11_+_78499087 0.58 ENSMUST00000017488.4
vitronectin
chr8_+_13037802 0.58 ENSMUST00000152034.1
ENSMUST00000128418.1
coagulation factor X
chr3_-_104818266 0.58 ENSMUST00000168015.1
Moloney leukemia virus 10
chr12_+_17690793 0.58 ENSMUST00000071858.3
hippocalcin-like 1
chr7_+_81114799 0.58 ENSMUST00000026820.4
solute carrier family 28 (sodium-coupled nucleoside transporter), member 1
chr10_-_128960965 0.57 ENSMUST00000026398.3
methyltransferase like 7B
chr13_+_64248649 0.56 ENSMUST00000181403.1
RIKEN cDNA 1810034E14 gene
chr2_-_13491900 0.56 ENSMUST00000091436.5
cubilin (intrinsic factor-cobalamin receptor)
chr10_+_79927330 0.54 ENSMUST00000105376.1
AT rich interactive domain 3A (BRIGHT-like)
chr4_-_132303331 0.53 ENSMUST00000040411.6
RAB42, member RAS oncogene family
chr4_+_136286061 0.53 ENSMUST00000069195.4
ENSMUST00000130658.1
zinc finger protein 46
chr17_-_73950172 0.53 ENSMUST00000024866.4
xanthine dehydrogenase
chr9_-_44288535 0.51 ENSMUST00000161354.1
ATP-binding cassette, sub-family G (WHITE), member 4
chr11_-_8664499 0.51 ENSMUST00000020695.6
tensin 3
chr16_-_34513944 0.50 ENSMUST00000151491.1
ENSMUST00000114960.2
kalirin, RhoGEF kinase
chrX_+_96455359 0.50 ENSMUST00000033553.7
hephaestin
chr12_+_59130767 0.49 ENSMUST00000175877.1
CTAGE family, member 5
chr19_+_46356880 0.48 ENSMUST00000086969.6
ENSMUST00000128455.1
transmembrane protein 180
chr16_-_17928136 0.47 ENSMUST00000003622.8
solute carrier family 25 (mitochondrial carrier, citrate transporter), member 1
chr8_+_12915879 0.47 ENSMUST00000110876.2
ENSMUST00000110879.2
mcf.2 transforming sequence-like
chr4_-_94650134 0.46 ENSMUST00000053419.2
leucine rich repeat containing 19
chrX_-_162565514 0.46 ENSMUST00000154424.1
RALBP1 associated Eps domain containing protein 2
chr7_-_31055594 0.46 ENSMUST00000039909.6
FXYD domain-containing ion transport regulator 1
chr4_-_83324239 0.45 ENSMUST00000048274.4
ENSMUST00000102823.3
tetratricopeptide repeat domain 39B
chrX_-_150814265 0.44 ENSMUST00000026302.6
ENSMUST00000129768.1
ENSMUST00000112699.2
melanoma antigen, family D, 2
chr2_+_25500750 0.44 ENSMUST00000015239.3
F-box and WD-40 domain protein 5
chr11_+_105967938 0.43 ENSMUST00000001963.7
angiotensin I converting enzyme (peptidyl-dipeptidase A) 1
chrX_+_10252305 0.43 ENSMUST00000049910.6
ornithine transcarbamylase
chr2_+_157456917 0.43 ENSMUST00000109529.1
Rous sarcoma oncogene
chr12_+_37241633 0.42 ENSMUST00000049874.7
alkylglycerol monooxygenase
chr12_+_59130994 0.41 ENSMUST00000177460.1
CTAGE family, member 5

Network of associatons between targets according to the STRING database.

First level regulatory network of Hnf4a

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 4.7 GO:0034443 regulation of lipoprotein oxidation(GO:0034442) negative regulation of lipoprotein oxidation(GO:0034443) multicellular organism lipid catabolic process(GO:0044240)
1.4 4.2 GO:0042851 glyoxylate catabolic process(GO:0009436) L-alanine metabolic process(GO:0042851)
1.1 6.7 GO:0015889 cobalamin transport(GO:0015889)
1.1 3.2 GO:0071929 alpha-tubulin acetylation(GO:0071929)
1.0 6.2 GO:0003100 regulation of systemic arterial blood pressure by endothelin(GO:0003100) vein smooth muscle contraction(GO:0014826)
0.8 2.5 GO:0006114 glycerol biosynthetic process(GO:0006114) positive regulation of transcription from RNA polymerase II promoter in response to acidic pH(GO:0061402)
0.8 3.2 GO:0035609 C-terminal protein deglutamylation(GO:0035609)
0.7 2.2 GO:0045062 extrathymic T cell selection(GO:0045062)
0.6 2.6 GO:0005984 disaccharide metabolic process(GO:0005984)
0.6 2.5 GO:0090365 regulation of mRNA modification(GO:0090365)
0.6 2.4 GO:0035279 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.6 1.7 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.5 1.5 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.5 1.5 GO:0071718 sodium-independent icosanoid transport(GO:0071718)
0.5 5.6 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.5 4.6 GO:0010898 positive regulation of triglyceride catabolic process(GO:0010898)
0.4 1.2 GO:0006210 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859) thymidine metabolic process(GO:0046104)
0.4 2.4 GO:0010886 positive regulation of cholesterol storage(GO:0010886)
0.4 1.2 GO:0006714 sesquiterpenoid metabolic process(GO:0006714)
0.4 1.9 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.4 2.2 GO:0015760 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.4 1.1 GO:1901052 sarcosine metabolic process(GO:1901052) sarcosine catabolic process(GO:1901053)
0.4 1.1 GO:2001293 fatty-acyl-CoA biosynthetic process(GO:0046949) malonyl-CoA metabolic process(GO:2001293)
0.4 1.4 GO:0030311 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.3 5.2 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.3 1.2 GO:0036115 medium-chain fatty-acyl-CoA catabolic process(GO:0036114) fatty-acyl-CoA catabolic process(GO:0036115) long-chain fatty-acyl-CoA catabolic process(GO:0036116) palmitic acid metabolic process(GO:1900533) palmitic acid biosynthetic process(GO:1900535)
0.3 2.7 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.3 1.2 GO:0015855 nucleobase transport(GO:0015851) pyrimidine nucleobase transport(GO:0015855)
0.3 1.2 GO:0008295 spermidine biosynthetic process(GO:0008295) putrescine biosynthetic process(GO:0009446)
0.3 1.5 GO:0000103 sulfate assimilation(GO:0000103)
0.3 2.4 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.3 0.9 GO:0061026 cardiac muscle tissue regeneration(GO:0061026) negative regulation of connective tissue replacement(GO:1905204)
0.3 1.7 GO:0042866 pyruvate biosynthetic process(GO:0042866)
0.3 1.6 GO:0098728 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.3 2.6 GO:0097461 ferric iron import into cell(GO:0097461) ferric iron import across plasma membrane(GO:0098706)
0.2 1.1 GO:0019244 lactate biosynthetic process from pyruvate(GO:0019244)
0.2 0.6 GO:0070973 COPI-coated vesicle budding(GO:0035964) protein localization to endoplasmic reticulum exit site(GO:0070973)
0.2 8.6 GO:0050892 intestinal absorption(GO:0050892)
0.2 0.8 GO:0010641 positive regulation of platelet-derived growth factor receptor signaling pathway(GO:0010641)
0.2 2.4 GO:0070423 nucleotide-binding oligomerization domain containing signaling pathway(GO:0070423) nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070431)
0.2 0.6 GO:0061302 smooth muscle cell-matrix adhesion(GO:0061302)
0.2 2.1 GO:1990035 parathyroid hormone secretion(GO:0035898) calcium ion import across plasma membrane(GO:0098703) calcium ion import into cell(GO:1990035)
0.2 1.7 GO:0061368 behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.2 4.4 GO:0010544 negative regulation of platelet activation(GO:0010544)
0.2 1.5 GO:0034379 very-low-density lipoprotein particle assembly(GO:0034379)
0.2 0.8 GO:0045915 positive regulation of catecholamine metabolic process(GO:0045915) positive regulation of dopamine metabolic process(GO:0045964)
0.2 1.0 GO:0098914 membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
0.2 0.5 GO:0015746 tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
0.2 1.1 GO:0031580 membrane raft polarization(GO:0001766) membrane raft distribution(GO:0031580)
0.2 0.6 GO:1903384 neuron intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:0036482) positive regulation of mitochondrial electron transport, NADH to ubiquinone(GO:1902958) regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway(GO:1903383) negative regulation of hydrogen peroxide-induced neuron intrinsic apoptotic signaling pathway(GO:1903384)
0.1 1.5 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.1 0.4 GO:2000170 positive regulation of peptidyl-cysteine S-nitrosylation(GO:2000170)
0.1 1.0 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.1 1.7 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.1 1.7 GO:0052696 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.1 0.5 GO:0009115 xanthine catabolic process(GO:0009115)
0.1 0.6 GO:2000427 positive regulation of apoptotic cell clearance(GO:2000427)
0.1 0.3 GO:0097155 fasciculation of sensory neuron axon(GO:0097155)
0.1 1.4 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.1 0.6 GO:1903797 positive regulation of inorganic anion transmembrane transport(GO:1903797)
0.1 0.6 GO:0015808 L-alanine transport(GO:0015808)
0.1 0.2 GO:0035963 response to interleukin-13(GO:0035962) cellular response to interleukin-13(GO:0035963)
0.1 0.3 GO:0032241 positive regulation of nucleobase-containing compound transport(GO:0032241)
0.1 1.3 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.1 2.0 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.1 0.4 GO:0051902 negative regulation of mitochondrial depolarization(GO:0051902)
0.1 0.5 GO:0016557 peroxisome membrane biogenesis(GO:0016557)
0.1 1.3 GO:0036158 outer dynein arm assembly(GO:0036158)
0.1 1.8 GO:0071392 cellular response to estradiol stimulus(GO:0071392)
0.1 4.5 GO:1901998 toxin transport(GO:1901998)
0.1 3.3 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.1 2.2 GO:0019369 arachidonic acid metabolic process(GO:0019369)
0.1 1.4 GO:0046697 decidualization(GO:0046697)
0.1 0.2 GO:1901668 regulation of superoxide dismutase activity(GO:1901668)
0.1 0.4 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.1 0.2 GO:0001193 maintenance of transcriptional fidelity during DNA-templated transcription elongation(GO:0001192) maintenance of transcriptional fidelity during DNA-templated transcription elongation from RNA polymerase II promoter(GO:0001193)
0.1 0.5 GO:0015747 urate transport(GO:0015747)
0.1 0.3 GO:2001045 closure of optic fissure(GO:0061386) negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.1 1.2 GO:0046485 ether lipid metabolic process(GO:0046485)
0.1 0.7 GO:1904668 mitotic spindle midzone assembly(GO:0051256) positive regulation of ubiquitin protein ligase activity(GO:1904668)
0.1 4.5 GO:0007566 embryo implantation(GO:0007566)
0.1 1.3 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.1 1.2 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.1 0.2 GO:0006553 lysine metabolic process(GO:0006553)
0.1 0.3 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.1 1.5 GO:0008340 determination of adult lifespan(GO:0008340)
0.1 0.1 GO:1904580 regulation of intracellular mRNA localization(GO:1904580)
0.1 0.9 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.1 0.9 GO:0008272 sulfate transport(GO:0008272)
0.1 0.4 GO:0070294 renal sodium ion absorption(GO:0070294)
0.1 1.6 GO:0015893 drug transport(GO:0015893)
0.1 0.8 GO:0050965 detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.1 0.2 GO:0006572 tyrosine catabolic process(GO:0006572)
0.1 0.3 GO:1902339 apoptotic process involved in mammary gland involution(GO:0060057) positive regulation of apoptotic process involved in mammary gland involution(GO:0060058) positive regulation of apoptotic process involved in morphogenesis(GO:1902339) regulation of mammary gland involution(GO:1903519) positive regulation of mammary gland involution(GO:1903521) positive regulation of apoptotic process involved in development(GO:1904747)
0.0 0.2 GO:2000210 positive regulation of anoikis(GO:2000210)
0.0 1.0 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.6 GO:0042761 very long-chain fatty acid biosynthetic process(GO:0042761)
0.0 0.9 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.0 0.1 GO:0045329 carnitine biosynthetic process(GO:0045329)
0.0 4.5 GO:0046889 positive regulation of lipid biosynthetic process(GO:0046889)
0.0 0.4 GO:0042053 regulation of dopamine metabolic process(GO:0042053)
0.0 0.6 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 1.0 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.9 GO:0044062 regulation of excretion(GO:0044062)
0.0 0.1 GO:0042450 arginine biosynthetic process via ornithine(GO:0042450)
0.0 0.4 GO:1904659 glucose transmembrane transport(GO:1904659)
0.0 0.1 GO:0048696 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339) regulation of collateral sprouting in absence of injury(GO:0048696)
0.0 0.2 GO:0032596 protein transport into membrane raft(GO:0032596)
0.0 1.6 GO:0021799 cerebral cortex radially oriented cell migration(GO:0021799)
0.0 0.2 GO:0090043 regulation of tubulin deacetylation(GO:0090043)
0.0 0.1 GO:0048014 Tie signaling pathway(GO:0048014)
0.0 0.8 GO:0048025 negative regulation of mRNA splicing, via spliceosome(GO:0048025)
0.0 0.1 GO:1900126 negative regulation of hyaluronan biosynthetic process(GO:1900126)
0.0 0.4 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.5 GO:0033344 cholesterol efflux(GO:0033344)
0.0 0.4 GO:0006825 copper ion transport(GO:0006825)
0.0 1.0 GO:0043001 Golgi to plasma membrane protein transport(GO:0043001)
0.0 1.3 GO:0048286 lung alveolus development(GO:0048286)
0.0 2.4 GO:0030518 intracellular steroid hormone receptor signaling pathway(GO:0030518)
0.0 1.4 GO:0051897 positive regulation of protein kinase B signaling(GO:0051897)
0.0 3.5 GO:0071772 response to BMP(GO:0071772) cellular response to BMP stimulus(GO:0071773)
0.0 0.3 GO:0043252 response to stilbenoid(GO:0035634) sodium-independent organic anion transport(GO:0043252)
0.0 0.2 GO:0045741 positive regulation of epidermal growth factor-activated receptor activity(GO:0045741)
0.0 2.3 GO:0035304 regulation of protein dephosphorylation(GO:0035304)
0.0 1.1 GO:0046426 negative regulation of JAK-STAT cascade(GO:0046426) negative regulation of STAT cascade(GO:1904893)
0.0 0.4 GO:0032292 myelination in peripheral nervous system(GO:0022011) peripheral nervous system axon ensheathment(GO:0032292)
0.0 0.4 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.5 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.0 0.6 GO:0033209 tumor necrosis factor-mediated signaling pathway(GO:0033209)
0.0 1.3 GO:0009166 nucleotide catabolic process(GO:0009166)
0.0 0.2 GO:0002360 T cell lineage commitment(GO:0002360)
0.0 0.1 GO:0046149 porphyrin-containing compound catabolic process(GO:0006787) tetrapyrrole catabolic process(GO:0033015) heme catabolic process(GO:0042167) pigment catabolic process(GO:0046149)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 11.1 GO:0045179 apical cortex(GO:0045179)
0.4 6.9 GO:0042627 chylomicron(GO:0042627)
0.4 3.2 GO:0097427 microtubule bundle(GO:0097427)
0.3 2.0 GO:0005579 membrane attack complex(GO:0005579)
0.2 1.9 GO:0045098 type III intermediate filament(GO:0045098)
0.2 3.6 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.2 1.4 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.2 0.6 GO:0005610 laminin-5 complex(GO:0005610)
0.1 0.6 GO:0043202 lysosomal lumen(GO:0043202)
0.1 0.6 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.1 4.1 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.1 0.6 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.1 1.1 GO:0035686 sperm fibrous sheath(GO:0035686)
0.1 0.8 GO:0020003 symbiont-containing vacuole(GO:0020003)
0.0 0.2 GO:1990130 Iml1 complex(GO:1990130)
0.0 4.1 GO:0005811 lipid particle(GO:0005811)
0.0 4.5 GO:0005814 centriole(GO:0005814)
0.0 0.1 GO:0031523 Myb complex(GO:0031523)
0.0 0.4 GO:0031931 TORC1 complex(GO:0031931)
0.0 0.8 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 1.7 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.9 GO:0031304 intrinsic component of mitochondrial inner membrane(GO:0031304)
0.0 0.4 GO:0097225 sperm midpiece(GO:0097225)
0.0 2.3 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 1.2 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 1.3 GO:0005882 intermediate filament(GO:0005882)
0.0 0.5 GO:0005779 integral component of peroxisomal membrane(GO:0005779)
0.0 1.1 GO:0009925 basal plasma membrane(GO:0009925)
0.0 2.6 GO:0005903 brush border(GO:0005903)
0.0 1.7 GO:0043198 dendritic shaft(GO:0043198)
0.0 1.8 GO:0016591 DNA-directed RNA polymerase II, holoenzyme(GO:0016591)
0.0 1.9 GO:0030176 integral component of endoplasmic reticulum membrane(GO:0030176)
0.0 1.4 GO:0030315 T-tubule(GO:0030315)
0.0 1.1 GO:0030136 clathrin-coated vesicle(GO:0030136)
0.0 0.1 GO:0000974 Prp19 complex(GO:0000974)
0.0 0.1 GO:0045298 tubulin complex(GO:0045298)
0.0 2.7 GO:0070382 exocytic vesicle(GO:0070382)
0.0 0.4 GO:0002102 podosome(GO:0002102)
0.0 0.7 GO:0005871 kinesin complex(GO:0005871)
0.0 0.4 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 3.4 GO:0009897 external side of plasma membrane(GO:0009897)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 12.6 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
1.6 6.2 GO:0031708 endothelin B receptor binding(GO:0031708)
1.0 3.0 GO:0033695 testosterone 16-alpha-hydroxylase activity(GO:0008390) oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.8 4.2 GO:0008453 alanine-glyoxylate transaminase activity(GO:0008453)
0.7 2.2 GO:0050309 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.7 6.7 GO:0031419 cobalamin binding(GO:0031419)
0.7 4.6 GO:0016936 galactoside binding(GO:0016936)
0.6 1.9 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.6 3.5 GO:0060228 phosphatidylcholine-sterol O-acyltransferase activator activity(GO:0060228)
0.6 3.4 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.6 1.7 GO:0004743 pyruvate kinase activity(GO:0004743)
0.5 1.4 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532) beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity(GO:0047223)
0.5 2.4 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.5 1.9 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.5 3.2 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.4 1.3 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.4 2.5 GO:0004126 cytidine deaminase activity(GO:0004126)
0.4 1.2 GO:0015389 pyrimidine- and adenine-specific:sodium symporter activity(GO:0015389)
0.4 1.2 GO:0050479 glyceryl-ether monooxygenase activity(GO:0050479)
0.4 1.9 GO:0004850 uridine phosphorylase activity(GO:0004850)
0.4 1.1 GO:0046997 sarcosine dehydrogenase activity(GO:0008480) oxidoreductase activity, acting on the CH-NH group of donors, flavin as acceptor(GO:0046997)
0.4 1.4 GO:0019970 interleukin-11 receptor activity(GO:0004921) interleukin-11 binding(GO:0019970)
0.4 1.8 GO:0004994 somatostatin receptor activity(GO:0004994)
0.3 1.0 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.3 2.6 GO:0052851 cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.3 2.4 GO:0035473 lipase binding(GO:0035473)
0.3 1.1 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.3 1.3 GO:0031849 olfactory receptor binding(GO:0031849)
0.2 3.3 GO:0070330 aromatase activity(GO:0070330)
0.2 1.6 GO:0008392 arachidonic acid epoxygenase activity(GO:0008392)
0.2 1.6 GO:0070699 type II activin receptor binding(GO:0070699)
0.2 1.1 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.2 0.6 GO:0005280 hydrogen:amino acid symporter activity(GO:0005280) L-tyrosine transmembrane transporter activity(GO:0005302)
0.2 1.2 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.2 1.2 GO:0002054 nucleobase binding(GO:0002054)
0.2 0.5 GO:0015137 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.2 1.2 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.1 2.7 GO:0004806 triglyceride lipase activity(GO:0004806)
0.1 1.5 GO:1990239 steroid hormone binding(GO:1990239)
0.1 2.0 GO:0019841 retinol binding(GO:0019841)
0.1 0.5 GO:0004854 xanthine dehydrogenase activity(GO:0004854) oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor(GO:0016726)
0.1 0.5 GO:0034040 lipid-transporting ATPase activity(GO:0034040) sterol-transporting ATPase activity(GO:0034041)
0.1 2.4 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.1 1.6 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 0.7 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.1 2.5 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.1 1.4 GO:0015125 bile acid transmembrane transporter activity(GO:0015125)
0.1 3.2 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 0.4 GO:0031711 tripeptidyl-peptidase activity(GO:0008240) peptidyl-dipeptidase activity(GO:0008241) bradykinin receptor binding(GO:0031711) metallodipeptidase activity(GO:0070573)
0.1 0.8 GO:0008131 primary amine oxidase activity(GO:0008131)
0.1 1.4 GO:0050700 CARD domain binding(GO:0050700)
0.1 1.1 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.1 3.4 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.1 0.9 GO:0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.1 1.2 GO:0097109 neuroligin family protein binding(GO:0097109)
0.1 0.8 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.1 0.6 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.1 0.3 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.1 0.3 GO:0042731 PH domain binding(GO:0042731)
0.1 0.9 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.1 0.5 GO:1901702 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.1 1.7 GO:0015238 drug transmembrane transporter activity(GO:0015238)
0.1 2.0 GO:0016645 oxidoreductase activity, acting on the CH-NH group of donors(GO:0016645)
0.1 0.8 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.1 0.5 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.1 0.2 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
0.1 0.8 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.1 1.7 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.1 0.2 GO:0015321 sodium-dependent phosphate transmembrane transporter activity(GO:0015321)
0.1 5.7 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.1 0.7 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 1.0 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.1 2.3 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.1 1.0 GO:0003841 1-acylglycerol-3-phosphate O-acyltransferase activity(GO:0003841)
0.0 1.7 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 1.2 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.4 GO:0071253 connexin binding(GO:0071253)
0.0 0.4 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.0 1.4 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.3 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
0.0 0.9 GO:0070410 co-SMAD binding(GO:0070410)
0.0 2.4 GO:0005518 collagen binding(GO:0005518)
0.0 0.3 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.0 0.3 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.1 GO:0016743 carboxyl- or carbamoyltransferase activity(GO:0016743)
0.0 0.5 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 2.1 GO:0017022 myosin binding(GO:0017022)
0.0 0.1 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.0 2.6 GO:0004553 hydrolase activity, hydrolyzing O-glycosyl compounds(GO:0004553)
0.0 0.8 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.6 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.1 GO:0099609 microtubule lateral binding(GO:0099609)
0.0 2.0 GO:0005262 calcium channel activity(GO:0005262)
0.0 0.3 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.3 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 2.7 GO:0044325 ion channel binding(GO:0044325)
0.0 0.0 GO:0009374 biotin binding(GO:0009374)
0.0 0.2 GO:0050897 cobalt ion binding(GO:0050897)
0.0 2.2 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.2 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.1 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 0.4 GO:0042605 peptide antigen binding(GO:0042605)
0.0 0.6 GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors(GO:0016627)
0.0 1.8 GO:0003774 motor activity(GO:0003774)
0.0 0.1 GO:0048018 receptor agonist activity(GO:0048018)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 6.9 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 2.0 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.1 6.6 PID ENDOTHELIN PATHWAY Endothelins
0.1 4.5 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 2.4 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.6 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 1.4 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 1.6 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 2.4 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 1.2 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 2.1 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 0.4 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 5.4 NABA ECM AFFILIATED Genes encoding proteins affiliated structurally or functionally to extracellular matrix proteins
0.0 0.8 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.0 0.6 PID ARF 3PATHWAY Arf1 pathway
0.0 0.9 PID NEPHRIN NEPH1 PATHWAY Nephrin/Neph1 signaling in the kidney podocyte
0.0 1.8 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.3 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 0.9 PID HES HEY PATHWAY Notch-mediated HES/HEY network
0.0 1.1 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.2 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.7 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.6 PID BMP PATHWAY BMP receptor signaling
0.0 0.3 ST ADRENERGIC Adrenergic Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.6 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.4 7.3 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.3 5.2 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.2 2.5 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.2 1.9 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.2 2.2 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.1 2.2 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.1 1.5 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 1.5 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.1 2.2 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.1 2.3 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.1 1.0 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.1 2.4 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.1 0.5 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.1 2.5 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.1 1.2 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.1 2.0 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.1 1.4 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.1 0.9 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.1 2.4 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.1 8.0 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.1 0.6 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 1.1 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.0 1.7 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.8 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 1.1 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 1.1 REACTOME FATTY ACYL COA BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis
0.0 1.6 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.0 1.3 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.4 REACTOME PECAM1 INTERACTIONS Genes involved in PECAM1 interactions
0.0 0.7 REACTOME KINESINS Genes involved in Kinesins
0.0 0.6 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 0.8 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 1.3 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.3 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 2.4 REACTOME G ALPHA Q SIGNALLING EVENTS Genes involved in G alpha (q) signalling events
0.0 0.8 REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM Genes involved in Transport of Mature Transcript to Cytoplasm
0.0 1.0 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 2.4 REACTOME MRNA PROCESSING Genes involved in mRNA Processing
0.0 0.2 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.5 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.6 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.6 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.0 0.9 REACTOME INTEGRATION OF ENERGY METABOLISM Genes involved in Integration of energy metabolism
0.0 0.1 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling