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2D miR_HR1_12

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Results for Plag1

Z-value: 0.91

Motif logo

Transcription factors associated with Plag1

Gene Symbol Gene ID Gene Info
ENSMUSG00000003282.3 pleiomorphic adenoma gene 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Plag1mm10_v2_chr4_-_3938354_3938401-0.156.3e-01Click!

Activity profile of Plag1 motif

Sorted Z-values of Plag1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr2_-_144332146 1.68 ENSMUST00000037423.3
ovo-like 2 (Drosophila)
chr6_+_90619241 1.52 ENSMUST00000032177.8
solute carrier family 41, member 3
chr2_-_92024502 1.44 ENSMUST00000028663.4
cAMP responsive element binding protein 3-like 1
chr19_-_10457447 1.35 ENSMUST00000171400.2
leucine rich repeat containing 10B
chr2_-_144331695 1.33 ENSMUST00000103171.3
ovo-like 2 (Drosophila)
chr17_+_72918298 1.19 ENSMUST00000024857.6
limb-bud and heart
chr1_+_132880273 1.19 ENSMUST00000027706.3
leucine rich repeat protein 2, neuronal
chr17_-_24689901 1.12 ENSMUST00000007236.4
synaptogyrin 3
chr5_-_37717122 1.12 ENSMUST00000094836.4
serine/threonine kinase 32B
chr5_-_93045022 1.08 ENSMUST00000061328.5
sosondowah ankyrin repeat domain family member B
chrX_+_8271133 0.99 ENSMUST00000127103.1
ENSMUST00000115591.1
solute carrier family 38, member 5
chr8_+_105413614 0.97 ENSMUST00000109355.2
leucine rich repeat containing 36
chr1_-_84696182 0.94 ENSMUST00000049126.6
delta/notch-like EGF-related receptor
chr7_-_128237984 0.92 ENSMUST00000078816.3
RIKEN cDNA 9130023H24 gene
chr13_-_71963713 0.91 ENSMUST00000077337.8
Iroquois related homeobox 1 (Drosophila)
chr4_-_43046196 0.90 ENSMUST00000036462.5
family with sequence similarity 214, member B
chr18_+_9212856 0.89 ENSMUST00000041080.5
frizzled homolog 8 (Drosophila)
chr6_-_48445825 0.86 ENSMUST00000114561.2
zinc finger protein 467
chr4_+_41760454 0.85 ENSMUST00000108040.1
interleukin 11 receptor, alpha chain 1
chr15_-_75566811 0.85 ENSMUST00000065417.8
lymphocyte antigen 6 complex, locus H
chr6_-_124768330 0.84 ENSMUST00000135626.1
enolase 2, gamma neuronal
chr6_+_78380700 0.83 ENSMUST00000101272.1
regenerating islet-derived 3 alpha
chr7_+_4119556 0.83 ENSMUST00000079415.5
tweety homolog 1 (Drosophila)
chr15_-_32244632 0.82 ENSMUST00000181536.1
RIKEN cDNA 0610007N19
chr7_-_19749464 0.82 ENSMUST00000075447.7
ENSMUST00000108450.3
poliovirus receptor-related 2
chrX_-_59134421 0.79 ENSMUST00000033473.5
fibroblast growth factor 13
chr7_+_4119525 0.78 ENSMUST00000119661.1
ENSMUST00000129423.1
tweety homolog 1 (Drosophila)
chr12_-_84698769 0.77 ENSMUST00000095550.2
synapse differentiation inducing 1 like
chr17_+_24488773 0.76 ENSMUST00000024958.7
CASK interacting protein 1
chr3_-_90465858 0.75 ENSMUST00000029540.6
natriuretic peptide receptor 1
chr1_-_184033998 0.73 ENSMUST00000050306.5
RIKEN cDNA 1700056E22 gene
chr17_+_37045980 0.73 ENSMUST00000174456.1
gamma-aminobutyric acid (GABA) B receptor, 1
chr12_+_24651346 0.73 ENSMUST00000020982.5
Kruppel-like factor 11
chr6_-_48445678 0.73 ENSMUST00000114556.1
zinc finger protein 467
chr2_-_25621923 0.72 ENSMUST00000028308.4
ENSMUST00000142087.1
transmembrane protein 141
chr19_-_58455398 0.72 ENSMUST00000026076.7
glial cell line derived neurotrophic factor family receptor alpha 1
chr7_+_141079759 0.71 ENSMUST00000066873.4
ENSMUST00000163041.1
plakophilin 3
chr9_+_46012810 0.71 ENSMUST00000126865.1
SIK family kinase 3
chr11_-_120648104 0.71 ENSMUST00000026134.2
myeloid-associated differentiation marker-like 2
chr10_-_109010955 0.70 ENSMUST00000105276.1
ENSMUST00000064054.7
synaptotagmin I
chr4_+_108879063 0.69 ENSMUST00000106650.2
RAB3B, member RAS oncogene family
chr12_-_44210061 0.69 ENSMUST00000015049.3
DnaJ (Hsp40) homolog, subfamily B, member 9
chr6_-_83033422 0.68 ENSMUST00000089651.5
docking protein 1
chrX_+_52791179 0.67 ENSMUST00000101588.1
coiled-coil domain containing 160
chr17_+_23660477 0.67 ENSMUST00000062967.8
coiled-coil domain containing 64B
chr2_-_152830615 0.66 ENSMUST00000146380.1
ENSMUST00000134902.1
ENSMUST00000134357.1
ENSMUST00000109820.3
BCL2-like 1
chr1_-_174921813 0.66 ENSMUST00000055294.3
gremlin 2 homolog, cysteine knot superfamily (Xenopus laevis)
chr3_+_94693556 0.66 ENSMUST00000090848.3
ENSMUST00000173981.1
ENSMUST00000173849.1
ENSMUST00000174223.1
selenium binding protein 2
chr4_-_134704235 0.65 ENSMUST00000054096.6
ENSMUST00000038628.3
mannosidase, alpha, class 1C, member 1
chr4_-_133498538 0.65 ENSMUST00000125541.1
TMF1-regulated nuclear protein 1
chr7_+_19083842 0.64 ENSMUST00000032568.7
ENSMUST00000122999.1
ENSMUST00000108473.3
ENSMUST00000108474.1
dystrophia myotonica-protein kinase
chr19_-_58454580 0.64 ENSMUST00000129100.1
ENSMUST00000123957.1
glial cell line derived neurotrophic factor family receptor alpha 1
chr1_+_120340569 0.64 ENSMUST00000037286.8
complement component 1, q subcomponent-like 2
chr8_-_89044162 0.63 ENSMUST00000034090.6
sal-like 1 (Drosophila)
chr4_+_120854786 0.63 ENSMUST00000071093.2
regulating synaptic membrane exocytosis 3
chr16_-_20730544 0.63 ENSMUST00000076422.5
thrombopoietin
chr4_-_134227359 0.62 ENSMUST00000105878.2
ENSMUST00000055892.3
ENSMUST00000169381.1
cation channel, sperm associated 4
chr14_+_55854115 0.62 ENSMUST00000168479.1
NYN domain and retroviral integrase containing
chr14_-_8378753 0.61 ENSMUST00000022269.5
oncoprotein induced transcript 1
chr7_-_143460989 0.61 ENSMUST00000167912.1
ENSMUST00000037287.6
cyclin-dependent kinase inhibitor 1C (P57)
chr7_+_25306085 0.60 ENSMUST00000119703.1
ENSMUST00000108409.1
transmembrane protein 145
chr16_-_22439570 0.60 ENSMUST00000170393.1
ets variant gene 5
chr19_-_58454435 0.60 ENSMUST00000169850.1
glial cell line derived neurotrophic factor family receptor alpha 1
chr3_+_94933041 0.60 ENSMUST00000090839.5
selenium binding protein 1
chr10_-_127041513 0.60 ENSMUST00000116231.2
methyltransferase like 21B
chr4_+_137913471 0.59 ENSMUST00000151110.1
endothelin converting enzyme 1
chr6_+_28981490 0.59 ENSMUST00000164104.1
predicted gene 3294
chr13_+_96542727 0.59 ENSMUST00000077672.4
ENSMUST00000109444.2
collagen, type IV, alpha 3 (Goodpasture antigen) binding protein
chr7_-_4546567 0.59 ENSMUST00000065957.5
synaptotagmin V
chr16_-_32797413 0.59 ENSMUST00000115116.1
ENSMUST00000041123.8
mucin 20
chr11_-_102296618 0.59 ENSMUST00000107132.2
ENSMUST00000073234.2
ataxin 7-like 3
chr17_+_33919332 0.58 ENSMUST00000025161.7
TAP binding protein
chr9_+_121760000 0.58 ENSMUST00000093772.3
zinc finger protein 651
chr1_+_184034381 0.58 ENSMUST00000048655.7
dual specificity phosphatase 10
chr14_+_55853997 0.58 ENSMUST00000100529.3
NYN domain and retroviral integrase containing
chr9_+_109931458 0.58 ENSMUST00000072772.5
ENSMUST00000035055.8
microtubule-associated protein 4
chr2_-_165234689 0.57 ENSMUST00000065438.6
cadherin 22
chr6_-_52191695 0.56 ENSMUST00000101395.2
homeobox A4
chr5_-_136567242 0.56 ENSMUST00000175975.2
ENSMUST00000176216.2
ENSMUST00000176745.1
cut-like homeobox 1
chr6_-_48445373 0.56 ENSMUST00000114563.1
ENSMUST00000114558.1
ENSMUST00000101443.3
ENSMUST00000114564.1
zinc finger protein 467
chr7_-_81454751 0.55 ENSMUST00000098331.3
ENSMUST00000178892.1
cytoplasmic polyadenylation element binding protein 1
chr3_-_152210032 0.55 ENSMUST00000144950.1
DnaJ (Hsp40) homolog, subfamily B, member 4
chr7_-_27396542 0.53 ENSMUST00000108363.1
spectrin beta, non-erythrocytic 4
chr16_-_10785525 0.53 ENSMUST00000038099.4
suppressor of cytokine signaling 1
chr12_+_79130777 0.53 ENSMUST00000021550.6
arginase type II
chr11_-_100759942 0.53 ENSMUST00000107363.2
potassium voltage-gated channel, subfamily H (eag-related), member 4
chr5_+_30913398 0.52 ENSMUST00000031055.5
elastin microfibril interfacer 1
chr17_+_37046555 0.52 ENSMUST00000172789.1
gamma-aminobutyric acid (GABA) B receptor, 1
chr6_+_39381175 0.52 ENSMUST00000031986.4
RAB19, member RAS oncogene family
chr12_-_4841583 0.51 ENSMUST00000020964.5
FK506 binding protein 1b
chr11_-_102082464 0.51 ENSMUST00000100398.4
membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2)
chrX_-_56822308 0.51 ENSMUST00000135542.1
ENSMUST00000114766.1
MAP7 domain containing 3
chr9_+_114978507 0.51 ENSMUST00000183104.1
oxysterol binding protein-like 10
chr12_-_84876479 0.50 ENSMUST00000163189.1
ENSMUST00000110254.2
ENSMUST00000002073.6
latent transforming growth factor beta binding protein 2
chr4_+_120161206 0.50 ENSMUST00000030384.4
endothelin 2
chr11_+_115877497 0.50 ENSMUST00000144032.1
myosin XVB
chr17_-_35201996 0.50 ENSMUST00000167924.1
ENSMUST00000025263.8
tumor necrosis factor
chr7_-_46179929 0.50 ENSMUST00000033123.6
ATP-binding cassette, sub-family C (CFTR/MRP), member 8
chr11_+_96849863 0.50 ENSMUST00000018816.7
coatomer protein complex, subunit zeta 2
chr7_-_19023538 0.50 ENSMUST00000036018.5
forkhead box A3
chr15_-_75747922 0.49 ENSMUST00000062002.4
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein A (avian)
chr7_-_29156160 0.49 ENSMUST00000144795.1
ENSMUST00000134176.1
ENSMUST00000164589.1
ENSMUST00000136256.1
family with sequence similarity 98, member C
chr3_-_152210017 0.49 ENSMUST00000029669.3
DnaJ (Hsp40) homolog, subfamily B, member 4
chr4_-_148151878 0.49 ENSMUST00000105706.1
ENSMUST00000030858.7
ENSMUST00000134261.1
F-box protein 6
chr5_+_137030275 0.49 ENSMUST00000041543.8
VGF nerve growth factor inducible
chr17_+_37045963 0.49 ENSMUST00000025338.9
gamma-aminobutyric acid (GABA) B receptor, 1
chr9_+_64179289 0.48 ENSMUST00000034965.6
small nuclear RNA activating complex, polypeptide 5
chr7_-_27446599 0.48 ENSMUST00000011895.7
spectrin beta, non-erythrocytic 4
chr14_-_34374617 0.48 ENSMUST00000023826.4
synuclein, gamma
chr16_+_17561885 0.47 ENSMUST00000171002.1
ENSMUST00000023441.4
purinergic receptor P2X, ligand-gated ion channel, 6
chr4_-_57916283 0.47 ENSMUST00000063816.5
RIKEN cDNA D630039A03 gene
chr12_-_12940600 0.46 ENSMUST00000130990.1
v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)
chr8_-_25101985 0.46 ENSMUST00000128715.1
ENSMUST00000064883.6
pleckstrin homology domain-containing, family A (phosphoinositide binding specific) member 2
chr10_+_59221945 0.45 ENSMUST00000182161.1
sosondowah ankyrin repeat domain family member C
chr6_+_86526271 0.45 ENSMUST00000180896.1
RIKEN cDNA 1600020E01 gene
chr7_+_139894696 0.45 ENSMUST00000151421.1
ENSMUST00000053445.9
ENSMUST00000121839.1
kinase non-catalytic C-lobe domain (KIND) containing 1
chr2_-_152831112 0.45 ENSMUST00000128172.1
BCL2-like 1
chr10_+_75037066 0.44 ENSMUST00000147802.1
ENSMUST00000020391.5
RAB36, member RAS oncogene family
chr15_-_99528017 0.44 ENSMUST00000023750.7
Fas apoptotic inhibitory molecule 2
chr4_+_136247932 0.44 ENSMUST00000102533.4
ENSMUST00000143942.1
transcription elongation factor A (SII), 3
chr7_+_127712709 0.44 ENSMUST00000047393.5
cardiotrophin 1
chr11_+_43528759 0.44 ENSMUST00000050574.6
cyclin J-like
chrX_+_143664365 0.44 ENSMUST00000126592.1
ENSMUST00000156449.1
ENSMUST00000155215.1
ENSMUST00000112865.1
p21 protein (Cdc42/Rac)-activated kinase 3
chr3_+_107101551 0.43 ENSMUST00000038695.1
potassium voltage-gated channel, shaker-related subfamily, member 2
chr11_+_116280939 0.43 ENSMUST00000055872.2
galanin receptor 2
chr4_-_126968124 0.43 ENSMUST00000106108.2
zinc finger, MYM-type 4
chr5_-_120812506 0.42 ENSMUST00000117193.1
ENSMUST00000130045.1
2'-5' oligoadenylate synthetase 1C
chr4_-_70534904 0.42 ENSMUST00000107359.2
multiple EGF-like-domains 9
chr15_+_33083110 0.42 ENSMUST00000042167.9
carboxypeptidase Q
chr19_-_58455161 0.42 ENSMUST00000135730.1
ENSMUST00000152507.1
glial cell line derived neurotrophic factor family receptor alpha 1
chr6_-_116716888 0.42 ENSMUST00000056623.6
transmembrane protein 72
chr2_+_170731807 0.42 ENSMUST00000029075.4
docking protein 5
chr11_+_102665566 0.41 ENSMUST00000100378.3
predicted gene 1564
chr11_-_100414829 0.41 ENSMUST00000066489.6
leprecan-like 4
chr11_-_106160708 0.41 ENSMUST00000106875.1
LIM domain containing 2
chr18_-_24709348 0.41 ENSMUST00000067987.1
predicted gene 9955
chr15_-_100599983 0.41 ENSMUST00000073837.6
POU domain, class 6, transcription factor 1
chr4_+_130308595 0.40 ENSMUST00000070532.7
fatty acid binding protein 3, muscle and heart
chr7_-_44997221 0.40 ENSMUST00000152341.1
BCL2-like 12 (proline rich)
chr7_+_30169861 0.40 ENSMUST00000085668.4
predicted gene 5113
chr4_-_43669141 0.40 ENSMUST00000056474.6
family with sequence similarity 221, member B
chr15_-_76126538 0.40 ENSMUST00000054022.5
ENSMUST00000089654.3
cDNA sequence BC024139
chr16_+_23429133 0.40 ENSMUST00000038730.6
receptor transporter protein 1
chr1_-_156036473 0.40 ENSMUST00000097527.3
ENSMUST00000027738.7
torsin A interacting protein 1
chr2_-_144270852 0.39 ENSMUST00000110030.3
sorting nexin 5
chr4_+_132974102 0.39 ENSMUST00000030693.6
Gardner-Rasheed feline sarcoma viral (Fgr) oncogene homolog
chr7_+_5020561 0.39 ENSMUST00000085427.3
zinc finger protein 865
chr7_+_19094594 0.39 ENSMUST00000049454.5
sine oculis-related homeobox 5
chr10_+_69212634 0.39 ENSMUST00000020101.5
Rho-related BTB domain containing 1
chr1_-_173367638 0.39 ENSMUST00000005470.4
ENSMUST00000111220.1
cell adhesion molecule 3
chr18_-_58209926 0.39 ENSMUST00000025497.6
fibrillin 2
chr17_+_43568641 0.38 ENSMUST00000169694.1
phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
chr11_-_69369377 0.38 ENSMUST00000092971.6
ENSMUST00000108661.1
chromodomain helicase DNA binding protein 3
chr2_+_156840966 0.38 ENSMUST00000109564.1
TGFB-induced factor homeobox 2
chr4_+_131921771 0.38 ENSMUST00000094666.3
transmembrane protein 200B
chr11_-_72135721 0.38 ENSMUST00000108508.2
ENSMUST00000075258.6
PITPNM family member 3
chr10_+_69213084 0.38 ENSMUST00000163497.1
ENSMUST00000164212.1
ENSMUST00000067908.7
Rho-related BTB domain containing 1
chr5_-_24447587 0.37 ENSMUST00000127194.1
ENSMUST00000115033.1
ENSMUST00000123167.1
ENSMUST00000030799.8
transmembrane and ubiquitin-like domain containing 1
chr4_+_41762309 0.37 ENSMUST00000108042.2
interleukin 11 receptor, alpha chain 1
chr6_-_142507805 0.37 ENSMUST00000134191.1
ENSMUST00000032373.5
lactate dehydrogenase B
chr7_-_46099752 0.37 ENSMUST00000180081.1
potassium inwardly rectifying channel, subfamily J, member 11
chr10_-_77902467 0.37 ENSMUST00000057608.4
leucine rich repeat containing 3
chr5_+_114568016 0.37 ENSMUST00000043650.7
family with sequence similarity 222, member A
chr10_-_127195709 0.37 ENSMUST00000038217.7
ENSMUST00000130855.1
ENSMUST00000116229.1
ENSMUST00000144322.1
deltex 3 homolog (Drosophila)
chr11_+_85832551 0.36 ENSMUST00000000095.6
T-box 2
chr19_-_42431778 0.36 ENSMUST00000048630.6
cartilage acidic protein 1
chr11_+_78037959 0.36 ENSMUST00000073660.6
flotillin 2
chr12_+_80790532 0.36 ENSMUST00000068519.5
RIKEN cDNA 4933426M11 gene
chr7_-_29155717 0.36 ENSMUST00000153251.1
family with sequence similarity 98, member C
chr4_-_152477433 0.36 ENSMUST00000159186.1
ENSMUST00000162017.1
ENSMUST00000030768.2
potassium voltage-gated channel, shaker-related subfamily, beta member 2
chr4_+_43669266 0.36 ENSMUST00000107864.1
transmembrane protein 8B
chr11_+_78037931 0.36 ENSMUST00000072289.5
ENSMUST00000100784.2
flotillin 2
chr19_-_34166037 0.36 ENSMUST00000025686.7
ankyrin repeat domain 22
chr4_+_150927918 0.35 ENSMUST00000139826.1
ENSMUST00000116257.1
tumor necrosis factor receptor superfamily, member 9
chr3_+_126596951 0.35 ENSMUST00000106402.1
calcium/calmodulin-dependent protein kinase II, delta
chr5_-_136883115 0.35 ENSMUST00000057497.6
ENSMUST00000111103.1
collagen, type XXVI, alpha 1
chr5_-_34187670 0.35 ENSMUST00000042701.6
ENSMUST00000119171.1
Max dimerization protein 4
chr14_-_30626196 0.35 ENSMUST00000112210.3
ENSMUST00000112211.2
ENSMUST00000112208.1
protein kinase C, delta
chr9_+_46012822 0.35 ENSMUST00000120463.2
ENSMUST00000120247.1
SIK family kinase 3
chr18_-_38211957 0.35 ENSMUST00000159405.1
ENSMUST00000160721.1
protocadherin 1
chr17_+_34647187 0.35 ENSMUST00000173984.1
activating transcription factor 6 beta
chr7_+_35334175 0.35 ENSMUST00000032705.6
ENSMUST00000085556.3
rhophilin, Rho GTPase binding protein 2
chrX_-_44790146 0.34 ENSMUST00000115056.1
DDB1 and CUL4 associated factor 12-like 1
chr17_-_24209377 0.34 ENSMUST00000024931.4
netrin 3
chr7_+_45335256 0.34 ENSMUST00000085351.4
histidine rich calcium binding protein
chr3_+_96161981 0.34 ENSMUST00000054356.9
myotubularin related protein 11
chr18_+_74442500 0.34 ENSMUST00000074157.6
myosin VB
chrX_-_133981765 0.34 ENSMUST00000113297.2
ENSMUST00000174542.1
ENSMUST00000033608.8
ENSMUST00000113294.1
synaptotagmin-like 4
chr17_-_28350747 0.34 ENSMUST00000080572.7
ENSMUST00000156862.1
TEA domain family member 3
chr7_+_28766747 0.33 ENSMUST00000170068.1
ENSMUST00000072965.4
sirtuin 2
chr3_+_126596993 0.33 ENSMUST00000163226.1
ENSMUST00000066466.6
ENSMUST00000169051.1
calcium/calmodulin-dependent protein kinase II, delta
chr10_-_81600857 0.33 ENSMUST00000151858.1
ENSMUST00000142948.1
ENSMUST00000072020.2
transducin-like enhancer of split 6, homolog of Drosophila E(spl)
chr5_-_24351604 0.33 ENSMUST00000036092.7
potassium voltage-gated channel, subfamily H (eag-related), member 2
chr11_+_4218220 0.33 ENSMUST00000020699.3
GATS protein-like 3
chr7_-_5038427 0.33 ENSMUST00000062428.4
zinc finger protein 784
chr11_-_94474088 0.33 ENSMUST00000107786.1
ENSMUST00000107791.1
ENSMUST00000103166.2
ENSMUST00000107792.1
ENSMUST00000100561.3
ENSMUST00000107793.1
ENSMUST00000107788.1
ENSMUST00000107790.1
ENSMUST00000107789.1
ENSMUST00000107785.1
ENSMUST00000021234.8
calcium channel, voltage-dependent, T type, alpha 1G subunit
chr7_-_27355944 0.33 ENSMUST00000003857.6
Sh3kbp1 binding protein 1
chr11_-_72489904 0.32 ENSMUST00000045303.3
spinster homolog 2
chr16_-_34095983 0.32 ENSMUST00000114973.1
ENSMUST00000114964.1
kalirin, RhoGEF kinase
chr9_+_50752758 0.32 ENSMUST00000034562.7
crystallin, alpha B

Network of associatons between targets according to the STRING database.

First level regulatory network of Plag1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.8 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
0.3 0.9 GO:0035627 ER to Golgi ceramide transport(GO:0035621) ceramide transport(GO:0035627)
0.3 1.9 GO:0014053 negative regulation of gamma-aminobutyric acid secretion(GO:0014053)
0.3 1.1 GO:0046898 response to cycloheximide(GO:0046898)
0.2 0.5 GO:0002874 regulation of chronic inflammatory response to antigenic stimulus(GO:0002874)
0.2 0.7 GO:1903903 regulation of establishment of T cell polarity(GO:1903903)
0.2 0.9 GO:0072272 proximal/distal pattern formation involved in metanephric nephron development(GO:0072272)
0.2 0.7 GO:0060300 regulation of cytokine activity(GO:0060300)
0.2 0.9 GO:0038163 thrombopoietin-mediated signaling pathway(GO:0038163)
0.2 0.6 GO:0072038 mesenchymal stem cell maintenance involved in nephron morphogenesis(GO:0072038)
0.2 1.5 GO:0070278 extracellular matrix constituent secretion(GO:0070278)
0.2 0.6 GO:0034959 substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.2 1.3 GO:1904672 regulation of somatic stem cell population maintenance(GO:1904672)
0.2 0.5 GO:1903722 regulation of centriole elongation(GO:1903722)
0.2 0.7 GO:0051944 positive regulation of neurotransmitter uptake(GO:0051582) positive regulation of dopamine uptake involved in synaptic transmission(GO:0051586) positive regulation of catecholamine uptake involved in synaptic transmission(GO:0051944)
0.2 0.5 GO:1901079 positive regulation of relaxation of muscle(GO:1901079)
0.2 0.6 GO:0010958 regulation of amino acid import(GO:0010958)
0.2 0.6 GO:0014722 regulation of skeletal muscle contraction by calcium ion signaling(GO:0014722)
0.2 0.8 GO:0060697 positive regulation of phospholipid catabolic process(GO:0060697)
0.2 0.5 GO:0099548 retrograde trans-synaptic signaling by soluble gas(GO:0098923) trans-synaptic signaling by nitric oxide(GO:0099548)
0.2 1.1 GO:2001199 negative regulation of dendritic cell differentiation(GO:2001199)
0.1 1.2 GO:0015074 DNA integration(GO:0015074)
0.1 0.6 GO:0055071 cellular manganese ion homeostasis(GO:0030026) Golgi calcium ion homeostasis(GO:0032468) manganese ion homeostasis(GO:0055071)
0.1 0.4 GO:0001543 ovarian follicle rupture(GO:0001543)
0.1 1.5 GO:0010459 negative regulation of heart rate(GO:0010459)
0.1 0.5 GO:0070368 positive regulation of hepatocyte differentiation(GO:0070368)
0.1 0.1 GO:1902856 negative regulation of nonmotile primary cilium assembly(GO:1902856)
0.1 0.4 GO:0007521 muscle cell fate determination(GO:0007521)
0.1 0.7 GO:0002159 desmosome assembly(GO:0002159)
0.1 0.6 GO:0051012 microtubule sliding(GO:0051012)
0.1 0.7 GO:0035022 positive regulation of Rac protein signal transduction(GO:0035022)
0.1 0.8 GO:0045196 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.1 0.2 GO:1904431 positive regulation of t-circle formation(GO:1904431)
0.1 0.7 GO:0035166 post-embryonic hemopoiesis(GO:0035166)
0.1 0.2 GO:1904580 regulation of intracellular mRNA localization(GO:1904580)
0.1 0.5 GO:0090290 positive regulation of osteoclast proliferation(GO:0090290)
0.1 0.3 GO:0014055 acetylcholine secretion, neurotransmission(GO:0014055) regulation of acetylcholine secretion, neurotransmission(GO:0014056) regulation of sulfur amino acid metabolic process(GO:0031335) musculoskeletal movement, spinal reflex action(GO:0050883)
0.1 0.4 GO:2001245 regulation of phosphatidylcholine biosynthetic process(GO:2001245)
0.1 1.2 GO:0045591 positive regulation of regulatory T cell differentiation(GO:0045591)
0.1 0.6 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.1 0.5 GO:0006384 transcription initiation from RNA polymerase III promoter(GO:0006384)
0.1 0.5 GO:0034441 plasma lipoprotein particle oxidation(GO:0034441)
0.1 0.6 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.1 0.5 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.1 0.4 GO:2001183 negative regulation of interleukin-12 secretion(GO:2001183)
0.1 0.7 GO:1902746 regulation of lens fiber cell differentiation(GO:1902746)
0.1 0.3 GO:0032917 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.1 0.4 GO:1902608 regulation of large conductance calcium-activated potassium channel activity(GO:1902606) positive regulation of large conductance calcium-activated potassium channel activity(GO:1902608)
0.1 0.3 GO:0006208 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.1 0.3 GO:0071651 positive regulation of chemokine (C-C motif) ligand 5 production(GO:0071651)
0.1 0.3 GO:0060282 positive regulation of oocyte development(GO:0060282) negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428) negative regulation of defense response to bacterium(GO:1900425)
0.1 0.3 GO:0036258 multivesicular body assembly(GO:0036258)
0.1 0.5 GO:0021631 optic nerve morphogenesis(GO:0021631)
0.1 0.2 GO:0009992 cellular water homeostasis(GO:0009992)
0.1 0.3 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.1 0.2 GO:0032474 otolith morphogenesis(GO:0032474)
0.1 0.2 GO:1903406 regulation of sodium:potassium-exchanging ATPase activity(GO:1903406)
0.1 0.4 GO:0035581 sequestering of extracellular ligand from receptor(GO:0035581) protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694) extracellular regulation of signal transduction(GO:1900115) extracellular negative regulation of signal transduction(GO:1900116)
0.1 0.4 GO:0019244 lactate biosynthetic process from pyruvate(GO:0019244)
0.1 0.2 GO:0044313 protein K6-linked deubiquitination(GO:0044313)
0.1 0.2 GO:0002023 reduction of food intake in response to dietary excess(GO:0002023)
0.1 0.4 GO:0030886 negative regulation of myeloid dendritic cell activation(GO:0030886)
0.1 0.2 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.1 0.1 GO:0060672 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.1 0.7 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.1 0.7 GO:0005513 detection of calcium ion(GO:0005513)
0.1 0.7 GO:0071763 nuclear membrane organization(GO:0071763)
0.1 1.0 GO:0007220 Notch receptor processing(GO:0007220)
0.1 0.2 GO:0045660 positive regulation of neutrophil differentiation(GO:0045660)
0.1 0.2 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.1 1.0 GO:0015816 glycine transport(GO:0015816)
0.1 1.2 GO:0046697 decidualization(GO:0046697)
0.1 0.4 GO:0048861 leukemia inhibitory factor signaling pathway(GO:0048861)
0.1 0.1 GO:0097117 guanylate kinase-associated protein clustering(GO:0097117)
0.1 0.1 GO:2000830 vacuolar phosphate transport(GO:0007037) positive regulation of parathyroid hormone secretion(GO:2000830)
0.1 0.2 GO:1903348 positive regulation of bicellular tight junction assembly(GO:1903348)
0.1 0.2 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.1 0.2 GO:0007439 ectodermal digestive tract development(GO:0007439) embryonic ectodermal digestive tract development(GO:0048611)
0.1 0.2 GO:0030070 insulin processing(GO:0030070)
0.1 0.2 GO:0070093 negative regulation of glucagon secretion(GO:0070093) positive regulation of testosterone secretion(GO:2000845)
0.1 0.2 GO:0002426 immunoglobulin production in mucosal tissue(GO:0002426)
0.1 0.2 GO:1905051 regulation of base-excision repair(GO:1905051) positive regulation of base-excision repair(GO:1905053)
0.1 0.3 GO:0032439 endosome localization(GO:0032439)
0.1 0.3 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.1 0.2 GO:1904995 negative regulation of leukocyte tethering or rolling(GO:1903237) negative regulation of leukocyte adhesion to vascular endothelial cell(GO:1904995)
0.1 0.2 GO:0015766 disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.1 0.5 GO:0006590 thyroid hormone generation(GO:0006590)
0.1 0.2 GO:0072086 specification of loop of Henle identity(GO:0072086)
0.1 0.3 GO:0048069 eye pigmentation(GO:0048069)
0.1 0.2 GO:0003162 atrioventricular node development(GO:0003162)
0.1 0.7 GO:0019236 response to pheromone(GO:0019236)
0.1 0.6 GO:0061635 regulation of protein complex stability(GO:0061635)
0.1 0.3 GO:1905169 protein localization to phagocytic vesicle(GO:1905161) regulation of protein localization to phagocytic vesicle(GO:1905169) positive regulation of protein localization to phagocytic vesicle(GO:1905171)
0.1 0.3 GO:0002589 regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589)
0.1 0.9 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.1 0.5 GO:0070474 positive regulation of uterine smooth muscle contraction(GO:0070474)
0.1 0.2 GO:1900135 positive regulation of renin secretion into blood stream(GO:1900135)
0.0 0.3 GO:0014042 positive regulation of neuron maturation(GO:0014042)
0.0 0.6 GO:1990440 positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress(GO:1990440)
0.0 0.3 GO:1902998 regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.0 0.1 GO:0015680 intracellular copper ion transport(GO:0015680)
0.0 0.7 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.2 GO:0050651 dermatan sulfate proteoglycan biosynthetic process(GO:0050651)
0.0 0.2 GO:1903575 cornified envelope assembly(GO:1903575)
0.0 1.0 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.7 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 0.2 GO:0007525 somatic muscle development(GO:0007525)
0.0 0.3 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.0 0.2 GO:0071442 positive regulation of histone H3-K14 acetylation(GO:0071442)
0.0 0.4 GO:0006449 regulation of translational termination(GO:0006449)
0.0 0.2 GO:0021993 initiation of neural tube closure(GO:0021993)
0.0 0.3 GO:0021886 hypothalamus gonadotrophin-releasing hormone neuron differentiation(GO:0021886) hypothalamus gonadotrophin-releasing hormone neuron development(GO:0021888)
0.0 0.7 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.3 GO:0007021 tubulin complex assembly(GO:0007021)
0.0 0.1 GO:0043181 vacuolar sequestering(GO:0043181)
0.0 0.1 GO:1900186 negative regulation of clathrin-mediated endocytosis(GO:1900186)
0.0 0.1 GO:0071211 protein targeting to vacuole involved in autophagy(GO:0071211)
0.0 1.1 GO:0095500 acetylcholine receptor signaling pathway(GO:0095500) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
0.0 0.1 GO:0086098 angiotensin-activated signaling pathway involved in heart process(GO:0086098)
0.0 0.6 GO:0048012 hepatocyte growth factor receptor signaling pathway(GO:0048012)
0.0 0.3 GO:1903849 regulation of aorta morphogenesis(GO:1903847) positive regulation of aorta morphogenesis(GO:1903849)
0.0 0.3 GO:0036481 intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:0036481)
0.0 0.7 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.1 GO:0070625 zymogen granule exocytosis(GO:0070625)
0.0 0.4 GO:0042760 very long-chain fatty acid catabolic process(GO:0042760)
0.0 0.2 GO:0099525 presynaptic dense core granule exocytosis(GO:0099525)
0.0 0.2 GO:0042758 long-chain fatty acid catabolic process(GO:0042758) diacylglycerol catabolic process(GO:0046340)
0.0 0.0 GO:0090135 actin filament branching(GO:0090135)
0.0 0.2 GO:0042494 detection of bacterial lipoprotein(GO:0042494)
0.0 0.1 GO:0002913 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913) protein K29-linked ubiquitination(GO:0035519)
0.0 0.2 GO:0032349 positive regulation of aldosterone metabolic process(GO:0032346) positive regulation of aldosterone biosynthetic process(GO:0032349)
0.0 0.2 GO:0035279 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.0 0.4 GO:0021796 cerebral cortex regionalization(GO:0021796)
0.0 0.2 GO:0045416 mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906) positive regulation of interleukin-8 biosynthetic process(GO:0045416)
0.0 0.5 GO:0043084 penile erection(GO:0043084)
0.0 0.1 GO:0034165 positive regulation of toll-like receptor 9 signaling pathway(GO:0034165)
0.0 0.3 GO:0015705 iodide transport(GO:0015705)
0.0 0.5 GO:0010745 negative regulation of macrophage derived foam cell differentiation(GO:0010745)
0.0 0.1 GO:0070172 positive regulation of tooth mineralization(GO:0070172)
0.0 0.3 GO:0010572 positive regulation of platelet activation(GO:0010572)
0.0 0.5 GO:0021707 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0 0.1 GO:0032237 activation of store-operated calcium channel activity(GO:0032237) positive regulation of store-operated calcium channel activity(GO:1901341)
0.0 0.2 GO:0031659 positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle(GO:0031659)
0.0 0.4 GO:1900121 negative regulation of receptor binding(GO:1900121)
0.0 0.4 GO:0014842 regulation of skeletal muscle satellite cell proliferation(GO:0014842)
0.0 0.2 GO:0007199 G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger(GO:0007199)
0.0 0.2 GO:0090063 positive regulation of microtubule nucleation(GO:0090063)
0.0 0.2 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0 1.2 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.7 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.0 0.6 GO:0038092 nodal signaling pathway(GO:0038092)
0.0 0.2 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
0.0 0.5 GO:0014046 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.0 0.2 GO:0016557 peroxisome membrane biogenesis(GO:0016557) regulation of peroxisome size(GO:0044375)
0.0 0.2 GO:0032489 regulation of Cdc42 protein signal transduction(GO:0032489)
0.0 0.1 GO:0000733 DNA strand renaturation(GO:0000733)
0.0 0.1 GO:0060217 hemangioblast cell differentiation(GO:0060217)
0.0 0.1 GO:0032423 regulation of mismatch repair(GO:0032423)
0.0 0.3 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.0 0.8 GO:0010763 positive regulation of fibroblast migration(GO:0010763)
0.0 1.0 GO:0033198 response to ATP(GO:0033198)
0.0 0.1 GO:0016115 terpenoid catabolic process(GO:0016115)
0.0 1.6 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 0.3 GO:0060770 regulation of epithelial cell proliferation involved in prostate gland development(GO:0060768) negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.0 0.4 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.3 GO:0061368 behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.0 0.7 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.0 0.5 GO:0007263 nitric oxide mediated signal transduction(GO:0007263)
0.0 0.4 GO:2000773 negative regulation of cellular senescence(GO:2000773)
0.0 0.1 GO:0003358 noradrenergic neuron development(GO:0003358)
0.0 0.0 GO:0071440 regulation of histone H3-K14 acetylation(GO:0071440)
0.0 1.1 GO:0060351 cartilage development involved in endochondral bone morphogenesis(GO:0060351)
0.0 0.2 GO:0070423 nucleotide-binding oligomerization domain containing signaling pathway(GO:0070423) nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070431)
0.0 0.1 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091)
0.0 0.2 GO:1901029 negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
0.0 0.2 GO:0021912 regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification(GO:0021912)
0.0 0.1 GO:0002268 follicular dendritic cell activation(GO:0002266) follicular dendritic cell differentiation(GO:0002268)
0.0 0.1 GO:0072361 regulation of glycolytic process by regulation of transcription from RNA polymerase II promoter(GO:0072361) regulation of glycolytic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072362)
0.0 0.1 GO:0045575 basophil activation involved in immune response(GO:0002276) basophil activation(GO:0045575)
0.0 0.5 GO:0001502 cartilage condensation(GO:0001502)
0.0 0.2 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.0 0.1 GO:0007620 copulation(GO:0007620)
0.0 0.2 GO:0071028 nuclear RNA surveillance(GO:0071027) nuclear mRNA surveillance(GO:0071028)
0.0 0.2 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.0 0.3 GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.0 0.3 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.3 GO:0061577 calcium ion transmembrane transport via high voltage-gated calcium channel(GO:0061577)
0.0 0.7 GO:0048240 sperm capacitation(GO:0048240)
0.0 0.4 GO:0070995 NADPH oxidation(GO:0070995)
0.0 0.1 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.0 0.1 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
0.0 0.2 GO:0090166 Golgi disassembly(GO:0090166)
0.0 0.1 GO:2000449 regulation of CD8-positive, alpha-beta T cell extravasation(GO:2000449)
0.0 0.4 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.2 GO:0097647 positive regulation of protein glycosylation(GO:0060050) calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.0 0.2 GO:0006707 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.1 GO:2000224 regulation of testosterone biosynthetic process(GO:2000224)
0.0 0.2 GO:0031642 negative regulation of myelination(GO:0031642)
0.0 0.3 GO:0010881 regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion(GO:0010881)
0.0 0.1 GO:0002355 detection of tumor cell(GO:0002355)
0.0 0.2 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.0 0.3 GO:0044126 regulation of growth of symbiont in host(GO:0044126) modulation of growth of symbiont involved in interaction with host(GO:0044144)
0.0 0.1 GO:0042373 vitamin K metabolic process(GO:0042373)
0.0 0.2 GO:0050961 detection of temperature stimulus involved in sensory perception(GO:0050961) detection of temperature stimulus involved in sensory perception of pain(GO:0050965)
0.0 0.1 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.0 0.1 GO:0071718 sodium-independent icosanoid transport(GO:0071718)
0.0 0.1 GO:0048023 positive regulation of melanin biosynthetic process(GO:0048023) positive regulation of secondary metabolite biosynthetic process(GO:1900378)
0.0 0.1 GO:1904706 negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
0.0 0.0 GO:0043379 memory T cell differentiation(GO:0043379)
0.0 0.1 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.0 0.2 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.0 0.7 GO:1902042 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902042)
0.0 0.2 GO:0002087 regulation of respiratory gaseous exchange by neurological system process(GO:0002087)
0.0 0.2 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.3 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 0.0 GO:1904154 positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
0.0 0.2 GO:0045955 negative regulation of vesicle fusion(GO:0031339) negative regulation of calcium ion-dependent exocytosis(GO:0045955)
0.0 0.5 GO:0097435 fibril organization(GO:0097435)
0.0 0.2 GO:0071493 cellular response to UV-B(GO:0071493)
0.0 0.1 GO:0006788 heme oxidation(GO:0006788)
0.0 0.4 GO:0043306 positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.0 0.5 GO:0006907 pinocytosis(GO:0006907)
0.0 0.2 GO:0048505 regulation of timing of cell differentiation(GO:0048505)
0.0 0.1 GO:0015760 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 0.1 GO:0000393 spliceosomal conformational changes to generate catalytic conformation(GO:0000393)
0.0 0.1 GO:0051612 negative regulation of neurotransmitter uptake(GO:0051581) negative regulation of serotonin uptake(GO:0051612)
0.0 0.1 GO:0010226 response to lithium ion(GO:0010226) cellular response to lithium ion(GO:0071285)
0.0 0.6 GO:0016578 histone deubiquitination(GO:0016578)
0.0 0.2 GO:0052697 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.0 0.1 GO:0051461 positive regulation of corticotropin secretion(GO:0051461)
0.0 0.2 GO:0045072 regulation of interferon-gamma biosynthetic process(GO:0045072) positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.0 0.2 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.0 0.3 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.2 GO:2000467 positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.0 0.2 GO:0018095 protein polyglutamylation(GO:0018095)
0.0 0.0 GO:1901963 canonical Wnt signaling pathway involved in heart development(GO:0061316) canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation(GO:0061324) regulation of cell proliferation involved in outflow tract morphogenesis(GO:1901963)
0.0 0.3 GO:0099563 modification of synaptic structure(GO:0099563)
0.0 0.1 GO:0035973 aggrephagy(GO:0035973)
0.0 0.1 GO:0019085 early viral transcription(GO:0019085)
0.0 0.1 GO:0030091 protein repair(GO:0030091)
0.0 0.2 GO:0019367 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.0 0.3 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.0 0.2 GO:2000582 positive regulation of microtubule motor activity(GO:2000576) regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 0.3 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.0 GO:1904502 regulation of lipophagy(GO:1904502) positive regulation of lipophagy(GO:1904504)
0.0 0.1 GO:0090315 negative regulation of protein targeting to membrane(GO:0090315)
0.0 0.1 GO:0018076 N-terminal peptidyl-lysine acetylation(GO:0018076)
0.0 0.7 GO:0050873 brown fat cell differentiation(GO:0050873)
0.0 0.3 GO:0010225 response to UV-C(GO:0010225)
0.0 0.3 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.2 GO:0050774 negative regulation of dendrite morphogenesis(GO:0050774)
0.0 0.1 GO:0043249 erythrocyte maturation(GO:0043249)
0.0 0.0 GO:2000321 positive regulation of T-helper 17 cell differentiation(GO:2000321)
0.0 0.1 GO:0072674 multinuclear osteoclast differentiation(GO:0072674) osteoclast fusion(GO:0072675)
0.0 0.0 GO:1903416 response to glycoside(GO:1903416)
0.0 0.2 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.0 0.2 GO:0016998 cell wall macromolecule catabolic process(GO:0016998)
0.0 0.1 GO:1901339 regulation of store-operated calcium channel activity(GO:1901339)
0.0 0.6 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.1 GO:0003096 renal sodium ion transport(GO:0003096) renal sodium ion absorption(GO:0070294)
0.0 0.1 GO:0032225 regulation of synaptic transmission, dopaminergic(GO:0032225)
0.0 0.7 GO:0006505 GPI anchor metabolic process(GO:0006505)
0.0 0.1 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.0 0.0 GO:0042939 glutathione transport(GO:0034635) tripeptide transport(GO:0042939)
0.0 0.0 GO:0090283 regulation of protein glycosylation in Golgi(GO:0090283) negative regulation of protein glycosylation in Golgi(GO:0090285)
0.0 0.1 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.4 GO:0090662 ATP hydrolysis coupled proton transport(GO:0015991) ATP hydrolysis coupled transmembrane transport(GO:0090662)
0.0 0.2 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.0 0.4 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.1 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.1 GO:0034088 maintenance of sister chromatid cohesion(GO:0034086) maintenance of mitotic sister chromatid cohesion(GO:0034088)
0.0 0.5 GO:0001954 positive regulation of cell-matrix adhesion(GO:0001954)
0.0 0.0 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.0 0.1 GO:0072526 pyridine-containing compound catabolic process(GO:0072526)
0.0 0.2 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.0 0.0 GO:0021666 rhombomere formation(GO:0021594) rhombomere 3 formation(GO:0021660) rhombomere 5 morphogenesis(GO:0021664) rhombomere 5 formation(GO:0021666)
0.0 0.1 GO:0007042 lysosomal lumen acidification(GO:0007042)
0.0 0.2 GO:0046498 S-adenosylhomocysteine metabolic process(GO:0046498)
0.0 0.0 GO:1902953 positive regulation of ER to Golgi vesicle-mediated transport(GO:1902953)
0.0 0.1 GO:0045187 regulation of circadian sleep/wake cycle(GO:0042749) regulation of circadian sleep/wake cycle, sleep(GO:0045187)
0.0 0.8 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.3 GO:0034142 toll-like receptor 4 signaling pathway(GO:0034142)
0.0 0.5 GO:0046326 positive regulation of glucose import(GO:0046326)
0.0 0.6 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.2 GO:0015721 bile acid and bile salt transport(GO:0015721)
0.0 0.2 GO:0042297 vocal learning(GO:0042297) imitative learning(GO:0098596) observational learning(GO:0098597)
0.0 0.2 GO:1902187 negative regulation of viral release from host cell(GO:1902187)
0.0 0.0 GO:0009414 response to water deprivation(GO:0009414)
0.0 0.5 GO:0046676 negative regulation of insulin secretion(GO:0046676)
0.0 0.3 GO:0048013 ephrin receptor signaling pathway(GO:0048013)
0.0 0.2 GO:0030575 nuclear body organization(GO:0030575)
0.0 0.2 GO:0009247 glycolipid biosynthetic process(GO:0009247)
0.0 0.7 GO:0030433 ER-associated ubiquitin-dependent protein catabolic process(GO:0030433)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.6 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.4 1.9 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.3 0.9 GO:1990851 Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.2 0.8 GO:0002111 BRCA2-BRAF35 complex(GO:0002111)
0.2 0.7 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.2 0.7 GO:0005914 spot adherens junction(GO:0005914)
0.1 0.9 GO:0008091 spectrin(GO:0008091)
0.1 0.6 GO:1990769 proximal neuron projection(GO:1990769)
0.1 0.3 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.1 0.6 GO:0090498 extrinsic component of Golgi membrane(GO:0090498)
0.1 0.8 GO:0036128 CatSper complex(GO:0036128)
0.1 0.3 GO:0032783 ELL-EAF complex(GO:0032783)
0.1 1.0 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.1 0.8 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 0.6 GO:0097422 tubular endosome(GO:0097422)
0.1 0.5 GO:0031233 intrinsic component of external side of plasma membrane(GO:0031233)
0.1 2.0 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.1 0.8 GO:0033093 Weibel-Palade body(GO:0033093)
0.1 0.9 GO:0072687 meiotic spindle(GO:0072687)
0.1 1.0 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.1 0.9 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.1 0.2 GO:0005588 collagen type V trimer(GO:0005588)
0.1 0.6 GO:0042825 TAP complex(GO:0042825)
0.1 0.2 GO:0042584 chromaffin granule membrane(GO:0042584)
0.1 0.2 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.1 0.3 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 0.8 GO:0044322 endoplasmic reticulum quality control compartment(GO:0044322)
0.1 0.2 GO:1990923 PET complex(GO:1990923)
0.1 0.9 GO:0031045 dense core granule(GO:0031045)
0.1 0.2 GO:0097447 dendritic tree(GO:0097447)
0.0 0.4 GO:0097512 cardiac myofibril(GO:0097512)
0.0 1.2 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.3 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.2 GO:1990111 spermatoproteasome complex(GO:1990111)
0.0 1.0 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.1 GO:0036488 CHOP-C/EBP complex(GO:0036488)
0.0 0.5 GO:0090543 Flemming body(GO:0090543)
0.0 0.2 GO:0000221 vacuolar proton-transporting V-type ATPase, V1 domain(GO:0000221)
0.0 0.2 GO:1990745 EARP complex(GO:1990745)
0.0 0.2 GO:1903440 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.0 0.1 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.8 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.0 0.6 GO:0000124 SAGA complex(GO:0000124)
0.0 0.1 GO:0032585 multivesicular body membrane(GO:0032585)
0.0 0.1 GO:0033193 Lsd1/2 complex(GO:0033193)
0.0 0.5 GO:0030126 COPI vesicle coat(GO:0030126)
0.0 0.2 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.3 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.3 GO:0034366 spherical high-density lipoprotein particle(GO:0034366)
0.0 0.2 GO:0034361 very-low-density lipoprotein particle(GO:0034361) triglyceride-rich lipoprotein particle(GO:0034385)
0.0 0.1 GO:0033257 Bcl3/NF-kappaB2 complex(GO:0033257)
0.0 0.1 GO:0044218 other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
0.0 0.3 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.0 0.5 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 1.3 GO:0034704 calcium channel complex(GO:0034704)
0.0 0.3 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.4 GO:0005639 integral component of nuclear inner membrane(GO:0005639) intrinsic component of nuclear inner membrane(GO:0031229)
0.0 0.3 GO:0045179 apical cortex(GO:0045179)
0.0 0.1 GO:0005766 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0 0.3 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 0.2 GO:0000178 exosome (RNase complex)(GO:0000178)
0.0 1.3 GO:0030667 secretory granule membrane(GO:0030667)
0.0 0.1 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.1 GO:0002081 inner acrosomal membrane(GO:0002079) outer acrosomal membrane(GO:0002081)
0.0 0.4 GO:0001527 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.3 GO:0031105 septin complex(GO:0031105)
0.0 0.7 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.2 GO:0043083 synaptic cleft(GO:0043083)
0.0 3.7 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.1 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 1.8 GO:0005581 collagen trimer(GO:0005581)
0.0 0.9 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.4 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.1 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.0 2.6 GO:0031227 intrinsic component of endoplasmic reticulum membrane(GO:0031227)
0.0 0.0 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.0 0.2 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.1 GO:1990393 3M complex(GO:1990393)
0.0 0.3 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.2 GO:0033178 proton-transporting two-sector ATPase complex, catalytic domain(GO:0033178)
0.0 0.4 GO:0045095 keratin filament(GO:0045095)
0.0 0.2 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.2 GO:0033391 chromatoid body(GO:0033391)
0.0 0.2 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.1 GO:0044194 cytolytic granule(GO:0044194)
0.0 0.2 GO:0042581 specific granule(GO:0042581)
0.0 0.2 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.4 GO:0030904 retromer complex(GO:0030904)
0.0 0.7 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.1 GO:0097342 ripoptosome(GO:0097342)
0.0 0.1 GO:0044233 ER-mitochondrion membrane contact site(GO:0044233)
0.0 0.1 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 0.7 GO:0030672 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 0.1 GO:0097443 sorting endosome(GO:0097443)
0.0 0.1 GO:0001739 sex chromatin(GO:0001739)
0.0 0.6 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.1 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 0.2 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 0.1 GO:0071012 catalytic step 1 spliceosome(GO:0071012)
0.0 0.1 GO:0097542 ciliary tip(GO:0097542)
0.0 0.5 GO:0045171 intercellular bridge(GO:0045171)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.6 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.3 1.9 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.3 1.2 GO:0019970 interleukin-11 receptor activity(GO:0004921) interleukin-11 binding(GO:0019970)
0.2 1.0 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.2 0.7 GO:0030348 syntaxin-3 binding(GO:0030348)
0.1 0.9 GO:0097001 ceramide binding(GO:0097001)
0.1 0.6 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.1 0.6 GO:0070976 TIR domain binding(GO:0070976)
0.1 0.6 GO:0015410 manganese-transporting ATPase activity(GO:0015410)
0.1 1.1 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.1 0.5 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.1 0.5 GO:0031708 endothelin B receptor binding(GO:0031708)
0.1 0.5 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733)
0.1 1.3 GO:0008430 selenium binding(GO:0008430)
0.1 0.5 GO:0004517 nitric-oxide synthase activity(GO:0004517)
0.1 1.1 GO:0051434 BH3 domain binding(GO:0051434)
0.1 0.6 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.1 0.4 GO:0004966 galanin receptor activity(GO:0004966)
0.1 0.4 GO:0070573 metallodipeptidase activity(GO:0070573)
0.1 2.1 GO:0035497 cAMP response element binding(GO:0035497)
0.1 0.3 GO:0071936 coreceptor activity involved in Wnt signaling pathway(GO:0071936)
0.1 0.1 GO:0046870 cadmium ion binding(GO:0046870)
0.1 0.3 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.1 0.4 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
0.1 0.4 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.1 0.8 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 1.1 GO:0015187 glycine transmembrane transporter activity(GO:0015187)
0.1 0.5 GO:0042610 CD8 receptor binding(GO:0042610)
0.1 0.3 GO:0022865 transmembrane electron transfer carrier(GO:0022865)
0.1 0.5 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.1 0.3 GO:0004145 diamine N-acetyltransferase activity(GO:0004145)
0.1 0.9 GO:0036122 BMP binding(GO:0036122)
0.1 0.3 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739)
0.1 0.6 GO:0046979 TAP1 binding(GO:0046978) TAP2 binding(GO:0046979)
0.1 0.3 GO:0034618 arginine binding(GO:0034618)
0.1 0.3 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.1 0.3 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.1 0.2 GO:0050253 sterol esterase activity(GO:0004771) retinyl-palmitate esterase activity(GO:0050253)
0.1 0.4 GO:0031849 olfactory receptor binding(GO:0031849)
0.1 0.4 GO:0034988 Fc-gamma receptor I complex binding(GO:0034988)
0.1 0.5 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.1 0.4 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.1 0.3 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.1 0.7 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.1 0.2 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.1 0.2 GO:0004948 calcitonin receptor activity(GO:0004948)
0.1 0.2 GO:0070615 nucleosome-dependent ATPase activity(GO:0070615)
0.1 0.3 GO:0034041 lipid-transporting ATPase activity(GO:0034040) sterol-transporting ATPase activity(GO:0034041)
0.1 0.5 GO:0035381 extracellular ATP-gated cation channel activity(GO:0004931) ATP-gated ion channel activity(GO:0035381)
0.1 0.3 GO:0042806 fucose binding(GO:0042806)
0.1 0.6 GO:0034452 dynactin binding(GO:0034452)
0.1 0.6 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.1 0.2 GO:0015275 stretch-activated, cation-selective, calcium channel activity(GO:0015275)
0.1 0.2 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.1 0.3 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.1 0.2 GO:0008515 sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.1 0.2 GO:0019002 GMP binding(GO:0019002)
0.1 0.7 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.1 0.3 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.1 0.8 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.0 2.0 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.2 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.0 0.5 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.0 0.2 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.0 0.7 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.1 GO:0005550 pheromone binding(GO:0005550)
0.0 0.2 GO:0034584 piRNA binding(GO:0034584)
0.0 0.5 GO:0019855 calcium channel inhibitor activity(GO:0019855)
0.0 0.7 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.2 GO:1904288 BAT3 complex binding(GO:1904288)
0.0 0.3 GO:0016936 galactoside binding(GO:0016936)
0.0 0.7 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.4 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.2 GO:0017108 5'-flap endonuclease activity(GO:0017108)
0.0 0.3 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
0.0 1.0 GO:0031489 myosin V binding(GO:0031489)
0.0 0.4 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.0 2.0 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.1 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.0 0.5 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.3 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.6 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.7 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.1 GO:0004008 copper-exporting ATPase activity(GO:0004008) copper-transporting ATPase activity(GO:0043682)
0.0 0.2 GO:0034056 estrogen response element binding(GO:0034056)
0.0 0.2 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.8 GO:0000400 four-way junction DNA binding(GO:0000400)
0.0 0.1 GO:0004346 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.0 0.2 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 0.1 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.0 0.2 GO:0070051 fibrinogen binding(GO:0070051)
0.0 0.1 GO:0004090 carbonyl reductase (NADPH) activity(GO:0004090)
0.0 0.7 GO:0003756 protein disulfide isomerase activity(GO:0003756) intramolecular oxidoreductase activity, transposing S-S bonds(GO:0016864)
0.0 0.2 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.0 0.1 GO:0005093 Rab GDP-dissociation inhibitor activity(GO:0005093)
0.0 0.4 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.5 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 1.1 GO:0005112 Notch binding(GO:0005112)
0.0 1.0 GO:0043325 phosphatidylinositol-3,4-bisphosphate binding(GO:0043325)
0.0 0.6 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.2 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.2 GO:0051185 coenzyme transporter activity(GO:0051185)
0.0 0.1 GO:0035651 AP-3 adaptor complex binding(GO:0035651)
0.0 0.1 GO:0004464 leukotriene-C4 synthase activity(GO:0004464)
0.0 0.5 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.0 0.2 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.0 0.3 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.2 GO:0043426 MRF binding(GO:0043426)
0.0 0.1 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0 0.2 GO:0031543 peptidyl-proline dioxygenase activity(GO:0031543)
0.0 1.3 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.3 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.3 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.3 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.4 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.3 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.1 GO:0004698 calcium-dependent protein kinase C activity(GO:0004698)
0.0 0.4 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.2 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.3 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.2 GO:0000182 rDNA binding(GO:0000182)
0.0 0.2 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.0 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.0 0.1 GO:0097003 adipokinetic hormone receptor activity(GO:0097003)
0.0 0.1 GO:0036310 annealing helicase activity(GO:0036310)
0.0 0.1 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.0 0.2 GO:0019865 immunoglobulin binding(GO:0019865)
0.0 0.2 GO:0009922 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.0 0.3 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.1 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219) calcium-induced calcium release activity(GO:0048763)
0.0 0.3 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.1 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 0.4 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 1.1 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.2 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.0 0.1 GO:0086038 calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential(GO:0086038)
0.0 0.1 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.2 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.1 GO:0016401 palmitoyl-CoA oxidase activity(GO:0016401)
0.0 0.1 GO:0004392 heme oxygenase (decyclizing) activity(GO:0004392)
0.0 0.4 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 0.2 GO:0050733 RS domain binding(GO:0050733)
0.0 0.5 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.7 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.2 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.2 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.2 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.1 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517) chondroitin sulfotransferase activity(GO:0034481)
0.0 0.3 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.1 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.0 0.4 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.2 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.1 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.1 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.0 0.1 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.2 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.3 GO:0016917 GABA receptor activity(GO:0016917)
0.0 0.3 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.0 0.1 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.3 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.8 GO:0019209 kinase activator activity(GO:0019209)
0.0 0.0 GO:0001888 glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0001888)
0.0 0.1 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.0 0.1 GO:0031685 adenosine receptor binding(GO:0031685)
0.0 0.1 GO:0001094 TFIID-class transcription factor binding(GO:0001094)
0.0 0.1 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.1 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0 0.3 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.0 0.1 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.0 0.1 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 0.0 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.0 0.8 GO:0030507 spectrin binding(GO:0030507)
0.0 0.3 GO:0015248 sterol transporter activity(GO:0015248)
0.0 0.5 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.1 GO:0008525 phosphatidylcholine transporter activity(GO:0008525)
0.0 0.2 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.1 GO:0001972 retinoic acid binding(GO:0001972)
0.0 1.1 GO:0000149 SNARE binding(GO:0000149)
0.0 0.1 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 0.0 GO:0045322 unmethylated CpG binding(GO:0045322)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.1 0.3 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.1 3.0 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 2.2 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 1.8 PID IFNG PATHWAY IFN-gamma pathway
0.0 0.1 PID ER NONGENOMIC PATHWAY Plasma membrane estrogen receptor signaling
0.0 0.5 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.8 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 0.2 PID RAC1 PATHWAY RAC1 signaling pathway
0.0 1.0 SIG CD40PATHWAYMAP Genes related to CD40 signaling
0.0 0.7 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.6 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 1.4 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.3 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.7 PID AURORA A PATHWAY Aurora A signaling
0.0 0.6 PID PI3KCI PATHWAY Class I PI3K signaling events
0.0 1.4 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.3 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.6 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.9 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.5 PID FAS PATHWAY FAS (CD95) signaling pathway
0.0 0.4 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.2 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.5 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.8 PID ENDOTHELIN PATHWAY Endothelins
0.0 0.6 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.1 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.9 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 0.3 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 0.9 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.6 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 1.8 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.3 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.3 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 0.2 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.9 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1 0.7 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle
0.1 1.2 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.1 2.9 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.6 REACTOME DAG AND IP3 SIGNALING Genes involved in DAG and IP3 signaling
0.0 0.0 REACTOME POST NMDA RECEPTOR ACTIVATION EVENTS Genes involved in Post NMDA receptor activation events
0.0 0.7 REACTOME REGULATION OF IFNG SIGNALING Genes involved in Regulation of IFNG signaling
0.0 0.8 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.5 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 0.4 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.0 0.5 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.4 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.7 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.0 0.7 REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0 0.1 REACTOME ADP SIGNALLING THROUGH P2RY1 Genes involved in ADP signalling through P2Y purinoceptor 1
0.0 0.5 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.5 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.4 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.0 0.9 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells
0.0 0.3 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.0 1.1 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 1.1 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.9 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 1.0 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 0.2 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.7 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.2 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.8 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.2 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 2.0 REACTOME REGULATION OF INSULIN SECRETION Genes involved in Regulation of Insulin Secretion
0.0 0.2 REACTOME GRB2 SOS PROVIDES LINKAGE TO MAPK SIGNALING FOR INTERGRINS Genes involved in GRB2:SOS provides linkage to MAPK signaling for Intergrins
0.0 0.7 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.3 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.3 REACTOME PLATELET AGGREGATION PLUG FORMATION Genes involved in Platelet Aggregation (Plug Formation)
0.0 0.4 REACTOME PLATELET SENSITIZATION BY LDL Genes involved in Platelet sensitization by LDL
0.0 0.1 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 1.0 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.2 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.5 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 0.3 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.2 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0 0.5 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.3 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.2 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors
0.0 0.6 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.5 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.3 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.2 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.0 0.2 REACTOME RIP MEDIATED NFKB ACTIVATION VIA DAI Genes involved in RIP-mediated NFkB activation via DAI
0.0 0.1 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.2 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA
0.0 0.3 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.2 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 1.5 REACTOME TRANSPORT OF INORGANIC CATIONS ANIONS AND AMINO ACIDS OLIGOPEPTIDES Genes involved in Transport of inorganic cations/anions and amino acids/oligopeptides
0.0 0.9 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 0.2 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 0.1 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.1 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.2 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.2 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism