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2D miR_HR1_12

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Results for Tead3_Tead4

Z-value: 1.67

Motif logo

Transcription factors associated with Tead3_Tead4

Gene Symbol Gene ID Gene Info
ENSMUSG00000002249.11 TEA domain family member 3
ENSMUSG00000030353.9 TEA domain family member 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Tead4mm10_v2_chr6_-_128300738_128300823-0.352.7e-01Click!
Tead3mm10_v2_chr17_-_28350747_283508200.293.7e-01Click!

Activity profile of Tead3_Tead4 motif

Sorted Z-values of Tead3_Tead4 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_+_171155512 4.39 ENSMUST00000111334.1
myelin protein zero
chr7_-_34133215 4.01 ENSMUST00000038537.8
WT1-interacting protein
chr10_+_24595434 3.24 ENSMUST00000020171.5
connective tissue growth factor
chr10_+_24595623 3.03 ENSMUST00000176228.1
ENSMUST00000129142.1
connective tissue growth factor
chr2_+_119351222 2.85 ENSMUST00000028780.3
ChaC, cation transport regulator 1
chr17_+_47436731 2.01 ENSMUST00000150819.2
expressed sequence AI661453
chr9_-_96437434 1.90 ENSMUST00000070500.2
cDNA sequence BC043934
chr5_+_66968416 1.88 ENSMUST00000038188.7
LIM and calponin homology domains 1
chr2_+_25456830 1.73 ENSMUST00000114265.2
ENSMUST00000102918.2
chloride intracellular channel 3
chr17_-_57000018 1.72 ENSMUST00000002740.2
persephin
chr17_+_47436615 1.60 ENSMUST00000037701.6
expressed sequence AI661453
chr3_-_129755305 1.57 ENSMUST00000029653.2
epidermal growth factor
chr6_-_37442095 1.56 ENSMUST00000041093.5
cAMP responsive element binding protein 3-like 2
chr18_+_23415400 1.52 ENSMUST00000115832.2
ENSMUST00000047954.7
dystrobrevin alpha
chr10_-_78591945 1.50 ENSMUST00000040580.6
synapse defective 1, Rho GTPase, homolog 1 (C. elegans)
chr2_+_19658055 1.47 ENSMUST00000052168.4
OTU domain containing 1
chrX_+_164438039 1.47 ENSMUST00000033755.5
ankyrin repeat and SOCS box-containing 11
chr16_+_30008657 1.46 ENSMUST00000181485.1
RIKEN cDNA 4632428C04 gene
chr6_+_88724667 1.40 ENSMUST00000163271.1
monoglyceride lipase
chr5_+_117363513 1.39 ENSMUST00000111959.1
WD repeat and SOCS box-containing 2
chr1_+_189728264 1.39 ENSMUST00000097442.2
protein tyrosine phosphatase, non-receptor type 14
chr6_+_125320633 1.35 ENSMUST00000176655.1
ENSMUST00000176110.1
sodium channel, nonvoltage-gated 1 alpha
chr14_-_57746044 1.34 ENSMUST00000173990.1
ENSMUST00000022531.7
large tumor suppressor 2
chr3_+_125404292 1.32 ENSMUST00000144344.1
N-deacetylase/N-sulfotransferase (heparin glucosaminyl) 4
chr3_+_125404072 1.22 ENSMUST00000173932.1
N-deacetylase/N-sulfotransferase (heparin glucosaminyl) 4
chr8_+_123186235 1.17 ENSMUST00000019422.4
dipeptidase 1 (renal)
chr15_+_78842632 1.16 ENSMUST00000059619.1
CDC42 effector protein (Rho GTPase binding) 1
chr1_-_72874877 1.16 ENSMUST00000027377.8
insulin-like growth factor binding protein 5
chr13_+_112464070 1.10 ENSMUST00000183663.1
ENSMUST00000184311.1
ENSMUST00000183886.1
interleukin 6 signal transducer
chr16_-_42340595 1.07 ENSMUST00000102817.4
growth associated protein 43
chr14_+_30879257 1.07 ENSMUST00000040715.6
musculoskeletal, embryonic nuclear protein 1
chr6_+_88724828 1.07 ENSMUST00000089449.2
monoglyceride lipase
chr7_-_31054815 1.04 ENSMUST00000071697.4
ENSMUST00000108110.3
FXYD domain-containing ion transport regulator 1
chr2_-_164857542 1.04 ENSMUST00000109316.1
ENSMUST00000156255.1
ENSMUST00000128110.1
ENSMUST00000109317.3
phospholipid transfer protein
chr10_-_22820126 1.03 ENSMUST00000049930.7
transcription factor 21
chr9_+_38752796 1.03 ENSMUST00000074740.2
olfactory receptor 920
chr11_+_70700606 1.01 ENSMUST00000137119.2
kinesin family member 1C
chr9_+_107299152 1.01 ENSMUST00000171568.1
cytokine inducible SH2-containing protein
chr10_-_5069044 0.97 ENSMUST00000095899.3
spectrin repeat containing, nuclear envelope 1
chr2_+_30595037 0.94 ENSMUST00000102853.3
CSA-conditional, T cell activation-dependent protein
chr7_-_132317198 0.93 ENSMUST00000080215.5
carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15
chr12_-_86884808 0.92 ENSMUST00000038422.6
interferon regulatory factor 2 binding protein-like
chr3_-_129332713 0.92 ENSMUST00000029658.7
glutamyl aminopeptidase
chr8_-_123894736 0.92 ENSMUST00000034453.4
actin, alpha 1, skeletal muscle
chr10_+_93641041 0.92 ENSMUST00000020204.4
netrin 4
chr2_-_31810580 0.92 ENSMUST00000057407.2
pyroglutamylated RFamide peptide
chr16_-_36784924 0.91 ENSMUST00000168279.1
ENSMUST00000164579.1
ENSMUST00000023616.2
solute carrier family 15 (H+/peptide transporter), member 2
chr6_-_128124312 0.91 ENSMUST00000127105.1
tetraspanin 9
chr15_+_31572179 0.91 ENSMUST00000161088.1
carboxymethylenebutenolidase-like (Pseudomonas)
chr12_-_86988676 0.90 ENSMUST00000095521.2
zinc finger, DHHC-type containing 22
chr2_-_181671622 0.90 ENSMUST00000054491.5
SRY-box containing gene 18
chr2_-_164857671 0.88 ENSMUST00000059954.7
phospholipid transfer protein
chr4_-_43558386 0.87 ENSMUST00000130353.1
talin 1
chr8_+_121950492 0.87 ENSMUST00000093078.6
ENSMUST00000170857.1
ENSMUST00000026354.8
ENSMUST00000174753.1
ENSMUST00000172511.1
BTG3 associated nuclear protein
chr8_+_84415348 0.86 ENSMUST00000121390.1
ENSMUST00000122053.1
calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
chr6_+_135065651 0.86 ENSMUST00000050104.7
G protein-coupled receptor, family C, group 5, member A
chr11_+_70700473 0.83 ENSMUST00000152618.2
ENSMUST00000102554.1
ENSMUST00000094499.4
ENSMUST00000072187.5
kinesin family member 1C
chr8_-_84237042 0.82 ENSMUST00000039480.5
zinc finger SWIM-type containing 4
chr2_+_160880642 0.81 ENSMUST00000109456.2
lipin 3
chr6_+_72636244 0.80 ENSMUST00000101278.2
predicted gene 15401
chr5_+_66968559 0.78 ENSMUST00000127184.1
LIM and calponin homology domains 1
chr7_-_4164442 0.78 ENSMUST00000140410.1
ENSMUST00000143825.1
CDC42 effector protein (Rho GTPase binding) 5
chr7_-_4164796 0.77 ENSMUST00000076831.6
CDC42 effector protein (Rho GTPase binding) 5
chr16_-_34095983 0.77 ENSMUST00000114973.1
ENSMUST00000114964.1
kalirin, RhoGEF kinase
chr19_-_34255325 0.77 ENSMUST00000039631.8
actin, alpha 2, smooth muscle, aorta
chr12_+_59095653 0.76 ENSMUST00000021384.4
melanoma inhibitory activity 2
chr11_+_87581041 0.76 ENSMUST00000018544.5
ENSMUST00000063156.4
ENSMUST00000107960.1
septin 4
chr17_-_27728889 0.75 ENSMUST00000167489.1
ENSMUST00000138970.1
ENSMUST00000114870.1
ENSMUST00000025054.2
SAM pointed domain containing ets transcription factor
chr13_-_113046357 0.74 ENSMUST00000022282.3
glutathione peroxidase 8 (putative)
chr11_-_115813621 0.74 ENSMUST00000041684.4
ENSMUST00000156812.1
CASK-interacting protein 2
chr8_+_54954728 0.73 ENSMUST00000033915.7
glycoprotein m6a
chr7_-_19698206 0.71 ENSMUST00000172808.1
ENSMUST00000174191.1
apolipoprotein E
chr10_+_39612934 0.71 ENSMUST00000019987.6
TRAF3 interacting protein 2
chr11_-_100939540 0.71 ENSMUST00000127638.1
signal transducer and activator of transcription 3
chr3_-_103737995 0.71 ENSMUST00000029440.8
olfactomedin-like 3
chr8_-_105966038 0.71 ENSMUST00000116429.2
ENSMUST00000034370.9
solute carrier family 12, member 4
chr6_+_80018877 0.69 ENSMUST00000147663.1
ENSMUST00000128718.1
ENSMUST00000126005.1
ENSMUST00000133918.1
leucine rich repeat transmembrane neuronal 4
chr17_-_47691403 0.69 ENSMUST00000152214.1
ENSMUST00000113299.1
prickle homolog 4 (Drosophila)
predicted gene 21981
chr18_+_50053282 0.66 ENSMUST00000148159.2
tumor necrosis factor, alpha-induced protein 8
chr17_-_24209377 0.66 ENSMUST00000024931.4
netrin 3
chr1_-_173333503 0.66 ENSMUST00000038227.4
Duffy blood group, chemokine receptor
chr8_-_94918012 0.65 ENSMUST00000077955.5
coiled-coil domain containing 102A
chrX_+_72987339 0.65 ENSMUST00000164800.1
ENSMUST00000114546.2
zinc finger protein 185
chr18_+_60911757 0.65 ENSMUST00000040359.5
arylsulfatase i
chr14_+_70890099 0.65 ENSMUST00000022699.8
glial cell line derived neurotrophic factor family receptor alpha 2
chr3_-_90695706 0.64 ENSMUST00000069960.5
ENSMUST00000117167.1
S100 calcium binding protein A9 (calgranulin B)
chr7_+_51880312 0.64 ENSMUST00000145049.1
growth arrest specific 2
chr6_+_80019008 0.62 ENSMUST00000126399.1
ENSMUST00000136421.1
leucine rich repeat transmembrane neuronal 4
chr10_-_41709297 0.61 ENSMUST00000019955.9
ENSMUST00000099932.3
coiled-coil domain containing 162
chr1_-_126830632 0.61 ENSMUST00000112583.1
ENSMUST00000094609.3
NCK-associated protein 5
chr14_-_30943275 0.61 ENSMUST00000006704.8
ENSMUST00000163118.1
inter-alpha trypsin inhibitor, heavy chain 1
chr11_-_69880971 0.61 ENSMUST00000050555.3
potassium channel tetramerisation domain containing 11
chr9_-_15627897 0.60 ENSMUST00000045513.6
coiled-coil domain containing 67
chr1_-_153186447 0.60 ENSMUST00000027753.6
laminin, gamma 2
chr15_-_53346118 0.60 ENSMUST00000077273.2
exostoses (multiple) 1
chrX_+_101376359 0.59 ENSMUST00000119080.1
gap junction protein, beta 1
chr19_-_57197556 0.59 ENSMUST00000099294.2
actin-binding LIM protein 1
chr11_-_100970887 0.58 ENSMUST00000060792.5
polymerase I and transcript release factor
chr7_-_27181149 0.57 ENSMUST00000071986.6
ENSMUST00000121848.1
melanoma inhibitory activity
chr11_-_32222233 0.57 ENSMUST00000150381.1
ENSMUST00000144902.1
ENSMUST00000020524.8
rhomboid family 1 (Drosophila)
chr2_+_20519776 0.57 ENSMUST00000114604.2
ENSMUST00000066509.3
enhancer trap locus 4
chr17_-_47010513 0.56 ENSMUST00000113337.2
ENSMUST00000113335.2
ubiquitin protein ligase E3 component n-recognin 2
chr18_+_50030977 0.56 ENSMUST00000145726.1
ENSMUST00000128377.1
tumor necrosis factor, alpha-induced protein 8
chr7_+_141468776 0.55 ENSMUST00000058746.5
CD151 antigen
chr6_+_47244359 0.55 ENSMUST00000060839.6
contactin associated protein-like 2
chr5_+_90518932 0.54 ENSMUST00000113179.2
ENSMUST00000128740.1
afamin
chr15_+_98632220 0.53 ENSMUST00000109150.1
calcium channel, voltage-dependent, beta 3 subunit
chr11_-_100939457 0.53 ENSMUST00000138438.1
signal transducer and activator of transcription 3
chr14_+_30715599 0.53 ENSMUST00000054230.4
Scm-like with four mbt domains 1
chr5_-_108795352 0.53 ENSMUST00000004943.1
transmembrane emp24 protein transport domain containing
chr10_-_53694823 0.52 ENSMUST00000171807.1
family with sequence similarity 184, member A
chr11_+_78188737 0.51 ENSMUST00000108322.2
RAB34, member of RAS oncogene family
chr11_-_100939357 0.51 ENSMUST00000092671.5
ENSMUST00000103114.1
signal transducer and activator of transcription 3
chr15_-_79254737 0.51 ENSMUST00000039752.3
solute carrier family 16 (monocarboxylic acid transporters), member 8
chr3_+_88364548 0.51 ENSMUST00000147948.1
ENSMUST00000147991.1
progestin and adipoQ receptor family member VI
chr8_+_14911663 0.50 ENSMUST00000084207.5
ENSMUST00000161162.1
ENSMUST00000110800.2
Rho guanine nucleotide exchange factor (GEF) 10
chr8_+_45507768 0.50 ENSMUST00000067065.7
ENSMUST00000098788.3
ENSMUST00000067107.7
ENSMUST00000171337.2
ENSMUST00000138049.1
ENSMUST00000141039.1
sorbin and SH3 domain containing 2
chr11_-_60913775 0.50 ENSMUST00000019075.3
predicted gene, Gm16515
chr3_-_84220853 0.50 ENSMUST00000154152.1
ENSMUST00000107693.2
ENSMUST00000107695.2
tripartite motif-containing 2
chr3_-_116423930 0.50 ENSMUST00000106491.2
CDC14 cell division cycle 14A
chr11_+_98412461 0.50 ENSMUST00000058295.5
v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)
chr11_+_78188806 0.49 ENSMUST00000056241.5
RAB34, member of RAS oncogene family
chr6_+_37530173 0.48 ENSMUST00000040987.7
aldo-keto reductase family 1, member D1
chr11_-_101170327 0.48 ENSMUST00000123864.1
pleckstrin homology domain containing, family H (with MyTH4 domain) member 3
chr1_-_136234113 0.48 ENSMUST00000120339.1
ENSMUST00000048668.8
RIKEN cDNA 5730559C18 gene
chr9_+_109095427 0.48 ENSMUST00000072093.6
plexin B1
chr7_-_19698383 0.47 ENSMUST00000173739.1
apolipoprotein E
chr4_+_42949814 0.47 ENSMUST00000037872.3
ENSMUST00000098112.2
DnaJ (Hsp40) homolog, subfamily B, member 5
chr10_+_5593718 0.46 ENSMUST00000051809.8
myc target 1
chr17_-_15375969 0.46 ENSMUST00000014917.7
delta-like 1 (Drosophila)
chr9_+_50752758 0.46 ENSMUST00000034562.7
crystallin, alpha B
chr15_-_42676967 0.45 ENSMUST00000022921.5
angiopoietin 1
chr12_+_76533540 0.45 ENSMUST00000075249.4
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr17_-_34214459 0.45 ENSMUST00000121995.1
predicted gene 15821
chr11_+_100415722 0.45 ENSMUST00000107400.2
FK506 binding protein 10
chr4_-_126163470 0.44 ENSMUST00000097891.3
SH3 domain containing 21
chr3_-_116424007 0.44 ENSMUST00000090464.4
CDC14 cell division cycle 14A
chr11_+_116853752 0.44 ENSMUST00000021173.7
major facilitator superfamily domain containing 11
chrX_+_20848543 0.43 ENSMUST00000001155.4
ENSMUST00000122312.1
ENSMUST00000120356.1
ENSMUST00000122850.1
v-raf murine sarcoma 3611 viral oncogene homolog
chr13_-_74807913 0.43 ENSMUST00000065629.4
calpastatin
chr17_+_48932368 0.43 ENSMUST00000046254.2
leucine rich repeat and fibronectin type III domain containing 2
chr11_-_54028090 0.42 ENSMUST00000020586.6
solute carrier family 22 (organic cation transporter), member 4
chr11_+_87664274 0.42 ENSMUST00000092800.5
ring finger protein 43
chr5_-_30960326 0.42 ENSMUST00000074840.5
prolactin regulatory element binding
chr15_-_3979432 0.42 ENSMUST00000022791.8
F-box protein 4
chr6_-_142507805 0.42 ENSMUST00000134191.1
ENSMUST00000032373.5
lactate dehydrogenase B
chr3_-_145649970 0.42 ENSMUST00000029846.3
cysteine rich protein 61
chr17_+_47593444 0.41 ENSMUST00000182209.1
cyclin D3
chr2_+_32288244 0.41 ENSMUST00000113377.1
ENSMUST00000100194.2
golgi autoantigen, golgin subfamily a, 2
chr11_+_78188422 0.41 ENSMUST00000002128.7
ENSMUST00000150941.1
RAB34, member of RAS oncogene family
chr17_-_28350747 0.40 ENSMUST00000080572.7
ENSMUST00000156862.1
TEA domain family member 3
chr4_+_94739518 0.40 ENSMUST00000071168.5
endothelial-specific receptor tyrosine kinase
chr17_-_28350600 0.40 ENSMUST00000114799.1
TEA domain family member 3
chr15_-_102136225 0.40 ENSMUST00000154032.1
SPRY domain containing 3
chr6_+_115675983 0.39 ENSMUST00000068960.9
RIKEN cDNA D830050J10 gene
chr3_+_89831352 0.38 ENSMUST00000050401.5
src homology 2 domain-containing transforming protein E
chr11_+_99047311 0.38 ENSMUST00000140772.1
insulin-like growth factor binding protein 4
chr5_-_30960236 0.38 ENSMUST00000088063.2
prolactin regulatory element binding
chr1_+_51289106 0.38 ENSMUST00000051572.6
serum deprivation response
chr2_-_26092149 0.38 ENSMUST00000114159.2
nucleus accumbens associated 2, BEN and BTB (POZ) domain containing
chr11_+_77462325 0.37 ENSMUST00000102493.1
coronin 6
chr4_-_43584386 0.37 ENSMUST00000107884.2
microseminoprotein, prostate associated
chr4_-_45012093 0.37 ENSMUST00000131991.1
zinc finger and BTB domain containing 5
chrX_+_155262443 0.37 ENSMUST00000026324.9
acyl-CoA thioesterase 9
chr1_+_135324770 0.37 ENSMUST00000059352.2
leiomodin 1 (smooth muscle)
chr19_-_23448322 0.36 ENSMUST00000036069.6
MAM domain containing 2
chrX_+_101254528 0.36 ENSMUST00000062000.4
forkhead box O4
chr9_-_96752822 0.36 ENSMUST00000152594.1
zinc finger and BTB domain containing 38
chr9_-_58158498 0.36 ENSMUST00000168864.2
immunoglobulin superfamily containing leucine-rich repeat
chr4_-_139968026 0.36 ENSMUST00000105031.2
kelch domain containing 7A
chr13_+_55152640 0.36 ENSMUST00000005452.5
fibroblast growth factor receptor 4
chr19_-_36119833 0.36 ENSMUST00000025718.8
ankyrin repeat domain 1 (cardiac muscle)
chr5_-_66151323 0.36 ENSMUST00000131838.1
RNA binding motif protein 47
chr11_+_100415697 0.36 ENSMUST00000001595.3
FK506 binding protein 10
chr8_-_122551316 0.36 ENSMUST00000067252.7
piezo-type mechanosensitive ion channel component 1
chr16_+_87553313 0.36 ENSMUST00000026700.7
Map3k7 C-terminal like
chr2_-_32775330 0.35 ENSMUST00000161089.1
ENSMUST00000066478.2
ENSMUST00000161950.1
tetratricopeptide repeat domain 16
chr8_-_36613937 0.35 ENSMUST00000033923.7
deleted in liver cancer 1
chr5_-_32133045 0.35 ENSMUST00000031308.6
predicted gene 10463
chr14_-_101729690 0.35 ENSMUST00000066461.3
predicted gene 9922
chr15_+_30172570 0.34 ENSMUST00000081728.5
catenin (cadherin associated protein), delta 2
chr6_-_90716489 0.34 ENSMUST00000101153.3
IQ motif and Sec7 domain 1
chr9_-_15627910 0.33 ENSMUST00000152377.1
ENSMUST00000115593.3
coiled-coil domain containing 67
chr2_+_91457501 0.33 ENSMUST00000028689.3
low density lipoprotein receptor-related protein 4
chr2_-_18048347 0.33 ENSMUST00000066885.5
SKI/DACH domain containing 1
chr19_+_46152505 0.32 ENSMUST00000026254.7
golgi-specific brefeldin A-resistance factor 1
chr19_-_57197435 0.32 ENSMUST00000111550.1
actin-binding LIM protein 1
chr4_+_57568144 0.32 ENSMUST00000102904.3
paralemmin 2
chr9_+_44101722 0.32 ENSMUST00000161703.1
ENSMUST00000161381.1
ENSMUST00000034654.7
membrane-type frizzled-related protein
chr5_+_77265454 0.31 ENSMUST00000080359.5
RE1-silencing transcription factor
chr19_+_42045792 0.31 ENSMUST00000172244.1
ENSMUST00000081714.4
4-hydroxy-2-oxoglutarate aldolase 1
chr9_-_107605295 0.31 ENSMUST00000102529.3
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3B
chr10_+_21992216 0.31 ENSMUST00000150089.1
ENSMUST00000100036.3
serum/glucocorticoid regulated kinase 1
chr2_-_69789568 0.31 ENSMUST00000094942.3
coiled-coil domain containing 173
chr4_+_98546710 0.30 ENSMUST00000102792.3
InaD-like (Drosophila)
chr11_-_115808068 0.30 ENSMUST00000132780.1
CASK-interacting protein 2
chr10_-_89533550 0.30 ENSMUST00000105297.1
nuclear receptor subfamily 1, group H, member 4
chr11_+_87664549 0.30 ENSMUST00000121782.2
ring finger protein 43
chr4_+_49059256 0.29 ENSMUST00000076670.2
RIKEN cDNA E130309F12 gene
chr1_-_157256682 0.29 ENSMUST00000134543.1
RAS protein activator like 2

Network of associatons between targets according to the STRING database.

First level regulatory network of Tead3_Tead4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.6 6.3 GO:0070318 positive regulation of G0 to G1 transition(GO:0070318)
0.4 1.8 GO:1902728 positive regulation of skeletal muscle satellite cell proliferation(GO:1902724) positive regulation of growth factor dependent skeletal muscle satellite cell proliferation(GO:1902728)
0.4 1.2 GO:1903002 regulation of lipid transport across blood brain barrier(GO:1903000) positive regulation of lipid transport across blood brain barrier(GO:1903002)
0.4 1.6 GO:0007262 STAT protein import into nucleus(GO:0007262)
0.4 1.9 GO:0042360 vitamin E metabolic process(GO:0042360)
0.4 1.1 GO:0070104 negative regulation of interleukin-6-mediated signaling pathway(GO:0070104)
0.4 2.5 GO:0035331 negative regulation of hippo signaling(GO:0035331)
0.4 2.5 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.3 1.0 GO:0060435 branchiomeric skeletal muscle development(GO:0014707) bronchiole development(GO:0060435) metanephric mesenchymal cell differentiation(GO:0072162) metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277)
0.3 4.4 GO:0045217 cell-cell junction maintenance(GO:0045217)
0.3 1.3 GO:0001827 inner cell mass cell fate commitment(GO:0001827)
0.3 1.5 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.3 0.9 GO:0048866 stem cell fate specification(GO:0048866)
0.3 1.2 GO:0014734 skeletal muscle hypertrophy(GO:0014734)
0.3 0.9 GO:0050883 regulation of sulfur amino acid metabolic process(GO:0031335) musculoskeletal movement, spinal reflex action(GO:0050883)
0.3 1.4 GO:1905171 protein localization to phagocytic vesicle(GO:1905161) regulation of protein localization to phagocytic vesicle(GO:1905169) positive regulation of protein localization to phagocytic vesicle(GO:1905171)
0.3 0.8 GO:0048209 regulation of vesicle targeting, to, from or within Golgi(GO:0048209)
0.3 2.8 GO:0006751 glutathione catabolic process(GO:0006751)
0.2 1.1 GO:0048014 Tie signaling pathway(GO:0048014)
0.2 0.6 GO:0070488 neutrophil aggregation(GO:0070488)
0.2 2.7 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.2 0.9 GO:0002003 angiotensin maturation(GO:0002003)
0.2 0.9 GO:0035426 extracellular matrix-cell signaling(GO:0035426)
0.2 0.9 GO:0042938 dipeptide transport(GO:0042938)
0.2 1.1 GO:1902732 positive regulation of chondrocyte proliferation(GO:1902732)
0.2 1.0 GO:1903797 positive regulation of sodium ion export(GO:1903275) positive regulation of sodium ion export from cell(GO:1903278) positive regulation of inorganic anion transmembrane transport(GO:1903797)
0.2 1.0 GO:0090292 nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.2 0.5 GO:0097101 negative regulation of auditory receptor cell differentiation(GO:0045608) arterial endothelial cell fate commitment(GO:0060844) blood vessel endothelial cell fate commitment(GO:0060846) endothelial cell fate specification(GO:0060847) Notch signaling pathway involved in arterial endothelial cell fate commitment(GO:0060853) blood vessel endothelial cell fate specification(GO:0097101)
0.2 0.8 GO:2000065 negative regulation of aldosterone metabolic process(GO:0032345) negative regulation of aldosterone biosynthetic process(GO:0032348) negative regulation of cortisol biosynthetic process(GO:2000065)
0.1 0.3 GO:1904252 negative regulation of bile acid biosynthetic process(GO:0070858) negative regulation of bile acid metabolic process(GO:1904252)
0.1 0.6 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.1 1.1 GO:0016198 axon choice point recognition(GO:0016198)
0.1 0.9 GO:0030240 skeletal muscle thin filament assembly(GO:0030240)
0.1 0.4 GO:1900477 negative regulation of G1/S transition of mitotic cell cycle by negative regulation of transcription from RNA polymerase II promoter(GO:1900477)
0.1 0.5 GO:0044849 estrous cycle(GO:0044849)
0.1 0.4 GO:0061144 alveolar secondary septum development(GO:0061144)
0.1 0.5 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.1 0.2 GO:1904580 regulation of intracellular mRNA localization(GO:1904580)
0.1 0.8 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.1 0.5 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.1 0.3 GO:0035964 COPI-coated vesicle budding(GO:0035964) protein localization to endoplasmic reticulum exit site(GO:0070973)
0.1 0.2 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.1 0.8 GO:0030382 sperm mitochondrion organization(GO:0030382)
0.1 0.3 GO:0009436 glyoxylate catabolic process(GO:0009436)
0.1 0.6 GO:0015014 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process(GO:0015014)
0.1 0.9 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.1 1.6 GO:1901629 regulation of presynaptic membrane organization(GO:1901629)
0.1 0.3 GO:1902396 protein localization to bicellular tight junction(GO:1902396)
0.1 0.4 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.1 0.8 GO:0061366 behavioral response to chemical pain(GO:0061366) behavioral response to formalin induced pain(GO:0061368)
0.1 0.3 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.1 0.4 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.1 0.4 GO:0019244 lactate biosynthetic process from pyruvate(GO:0019244)
0.1 0.4 GO:0060591 chondroblast differentiation(GO:0060591)
0.1 0.2 GO:0072034 renal vesicle induction(GO:0072034)
0.1 0.5 GO:0007021 tubulin complex assembly(GO:0007021)
0.1 0.6 GO:0007406 negative regulation of neuroblast proliferation(GO:0007406)
0.1 0.3 GO:0003219 cardiac right ventricle formation(GO:0003219)
0.1 0.4 GO:0015879 carnitine transport(GO:0015879)
0.1 1.2 GO:0050667 homocysteine metabolic process(GO:0050667)
0.1 0.7 GO:0060576 positive regulation of cell fate commitment(GO:0010455) intestinal epithelial cell development(GO:0060576)
0.1 0.2 GO:2000729 positive regulation of mesenchymal cell proliferation involved in ureter development(GO:2000729)
0.1 0.9 GO:0046543 development of secondary female sexual characteristics(GO:0046543)
0.1 0.5 GO:0072307 metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
0.1 1.5 GO:0001946 lymphangiogenesis(GO:0001946)
0.1 0.6 GO:0015868 purine ribonucleotide transport(GO:0015868)
0.1 0.4 GO:0090306 spindle assembly involved in meiosis(GO:0090306)
0.1 0.8 GO:0055059 asymmetric neuroblast division(GO:0055059)
0.1 0.2 GO:0042125 protein glycosylation at cell surface(GO:0033575) protein galactosylation at cell surface(GO:0033580) protein galactosylation(GO:0042125)
0.1 0.2 GO:0051387 negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.1 0.3 GO:1903367 positive regulation of fear response(GO:1903367) positive regulation of behavioral fear response(GO:2000987)
0.1 0.2 GO:1902896 terminal web assembly(GO:1902896)
0.1 0.3 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.1 0.3 GO:0032804 negative regulation of low-density lipoprotein particle receptor catabolic process(GO:0032804)
0.1 0.5 GO:0006707 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.1 0.1 GO:1904685 positive regulation of metalloendopeptidase activity(GO:1904685)
0.0 0.2 GO:0016095 polyprenol catabolic process(GO:0016095)
0.0 0.4 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
0.0 0.2 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.0 0.9 GO:0007175 negative regulation of epidermal growth factor-activated receptor activity(GO:0007175)
0.0 0.1 GO:0032241 positive regulation of nucleobase-containing compound transport(GO:0032241)
0.0 0.3 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.0 0.2 GO:0010360 negative regulation of anion channel activity(GO:0010360)
0.0 1.8 GO:0006890 retrograde vesicle-mediated transport, Golgi to ER(GO:0006890)
0.0 0.4 GO:0035878 nail development(GO:0035878)
0.0 0.5 GO:0070423 nucleotide-binding oligomerization domain containing signaling pathway(GO:0070423) nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070431)
0.0 1.9 GO:0055078 sodium ion homeostasis(GO:0055078)
0.0 0.1 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0 0.3 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.6 GO:0033141 positive regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033141)
0.0 1.3 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.0 0.2 GO:0060178 regulation of exocyst localization(GO:0060178)
0.0 0.2 GO:1901668 regulation of superoxide dismutase activity(GO:1901668)
0.0 1.0 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.5 GO:0061577 calcium ion transmembrane transport via high voltage-gated calcium channel(GO:0061577)
0.0 1.0 GO:0060259 regulation of feeding behavior(GO:0060259)
0.0 0.3 GO:1990504 dense core granule exocytosis(GO:1990504)
0.0 0.1 GO:1905053 regulation of base-excision repair(GO:1905051) positive regulation of base-excision repair(GO:1905053)
0.0 0.2 GO:0010572 positive regulation of platelet activation(GO:0010572)
0.0 0.2 GO:0060125 negative regulation of growth hormone secretion(GO:0060125)
0.0 0.2 GO:1903847 regulation of aorta morphogenesis(GO:1903847) positive regulation of aorta morphogenesis(GO:1903849)
0.0 1.0 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.9 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.0 0.4 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.4 GO:2000675 negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.0 0.7 GO:0002230 positive regulation of defense response to virus by host(GO:0002230)
0.0 0.2 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
0.0 0.4 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.0 0.1 GO:0035522 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.0 0.9 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.1 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.0 0.4 GO:0035994 response to muscle stretch(GO:0035994)
0.0 0.1 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.0 0.8 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.1 GO:2000721 positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721)
0.0 0.2 GO:0033631 cell-cell adhesion mediated by integrin(GO:0033631)
0.0 0.1 GO:0003220 left ventricular cardiac muscle tissue morphogenesis(GO:0003220)
0.0 0.2 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0 0.2 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.8 GO:0019432 triglyceride biosynthetic process(GO:0019432)
0.0 0.3 GO:0070886 positive regulation of calcineurin-NFAT signaling cascade(GO:0070886)
0.0 0.1 GO:0097201 negative regulation of transcription from RNA polymerase II promoter in response to stress(GO:0097201)
0.0 0.8 GO:0055090 acylglycerol homeostasis(GO:0055090) triglyceride homeostasis(GO:0070328)
0.0 1.3 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 0.4 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.0 0.0 GO:0060836 lymphatic endothelial cell differentiation(GO:0060836)
0.0 0.1 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.0 0.1 GO:0046946 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.0 1.6 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.0 0.2 GO:1900025 negative regulation of substrate adhesion-dependent cell spreading(GO:1900025)
0.0 0.5 GO:0035329 hippo signaling(GO:0035329)
0.0 0.2 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.0 0.2 GO:0090336 negative regulation of granulocyte differentiation(GO:0030853) positive regulation of brown fat cell differentiation(GO:0090336)
0.0 0.1 GO:0002266 follicular dendritic cell activation(GO:0002266) follicular dendritic cell differentiation(GO:0002268)
0.0 0.2 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.0 0.1 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.0 0.5 GO:0032011 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 1.0 GO:0032611 interleukin-1 beta production(GO:0032611)
0.0 0.6 GO:0051491 positive regulation of filopodium assembly(GO:0051491)
0.0 0.2 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.8 GO:0001658 branching involved in ureteric bud morphogenesis(GO:0001658)
0.0 0.2 GO:0014067 negative regulation of phosphatidylinositol 3-kinase signaling(GO:0014067)
0.0 0.6 GO:0007520 myoblast fusion(GO:0007520)
0.0 0.2 GO:0034389 lipid particle organization(GO:0034389)
0.0 0.5 GO:0051180 vitamin transport(GO:0051180)
0.0 0.8 GO:0019319 hexose biosynthetic process(GO:0019319)
0.0 0.4 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 0.1 GO:0060283 negative regulation of oocyte development(GO:0060283) negative regulation of oocyte maturation(GO:1900194)
0.0 0.1 GO:0071340 skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
0.0 0.4 GO:0010737 protein kinase A signaling(GO:0010737)
0.0 0.1 GO:0072189 ureter development(GO:0072189)
0.0 0.2 GO:0038092 nodal signaling pathway(GO:0038092)
0.0 0.0 GO:1901252 regulation of intracellular transport of viral material(GO:1901252)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.2 1.2 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.2 0.6 GO:0005607 laminin-2 complex(GO:0005607)
0.2 0.8 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.1 7.2 GO:0005801 cis-Golgi network(GO:0005801)
0.1 1.2 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.1 2.5 GO:0043196 varicosity(GO:0043196)
0.1 0.3 GO:1990667 PCSK9-AnxA2 complex(GO:1990667)
0.1 0.9 GO:0031983 vesicle lumen(GO:0031983)
0.1 0.3 GO:0032280 symmetric synapse(GO:0032280)
0.1 1.0 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.1 1.0 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1 1.7 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.1 0.7 GO:0097227 sperm annulus(GO:0097227)
0.1 1.5 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.1 1.1 GO:0031527 filopodium membrane(GO:0031527)
0.1 1.6 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.1 1.3 GO:0034706 sodium channel complex(GO:0034706)
0.1 0.5 GO:1990454 L-type voltage-gated calcium channel complex(GO:1990454)
0.0 0.5 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.0 2.5 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.5 GO:0043219 lateral loop(GO:0043219)
0.0 1.5 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.1 GO:0034271 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.0 4.2 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 0.2 GO:1990130 Iml1 complex(GO:1990130)
0.0 3.6 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 0.2 GO:1990357 terminal web(GO:1990357)
0.0 0.6 GO:0005922 connexon complex(GO:0005922)
0.0 0.3 GO:0016600 flotillin complex(GO:0016600)
0.0 1.8 GO:0005871 kinesin complex(GO:0005871)
0.0 0.2 GO:0061689 tricellular tight junction(GO:0061689)
0.0 0.1 GO:0033269 internode region of axon(GO:0033269)
0.0 0.3 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.0 0.3 GO:0030130 clathrin coat of trans-Golgi network vesicle(GO:0030130)
0.0 0.2 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 1.2 GO:0031985 Golgi cisterna(GO:0031985)
0.0 0.4 GO:0071564 npBAF complex(GO:0071564)
0.0 0.1 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.0 0.3 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.1 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.2 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.0 0.2 GO:0099634 postsynaptic specialization membrane(GO:0099634)
0.0 0.1 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.2 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 2.3 GO:0032432 actin filament bundle(GO:0032432)
0.0 0.1 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.4 GO:0090568 NuRD complex(GO:0016581) CHD-type complex(GO:0090545) nuclear transcriptional repressor complex(GO:0090568)
0.0 0.6 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.2 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.2 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.2 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.2 GO:0044754 autolysosome(GO:0044754)
0.0 0.6 GO:0044295 axonal growth cone(GO:0044295)
0.0 2.7 GO:0044798 nuclear transcription factor complex(GO:0044798)
0.0 1.0 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 1.4 GO:0005604 basement membrane(GO:0005604)
0.0 2.5 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.1 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.8 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.4 1.2 GO:0046911 metal chelating activity(GO:0046911)
0.4 1.1 GO:0004923 interleukin-6 receptor activity(GO:0004915) leukemia inhibitory factor receptor activity(GO:0004923) interleukin-6 binding(GO:0019981)
0.4 2.5 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.3 0.9 GO:0050656 3'-phosphoadenosine 5'-phosphosulfate binding(GO:0050656)
0.3 0.9 GO:0042936 dipeptide transporter activity(GO:0042936)
0.3 1.2 GO:0070573 metallodipeptidase activity(GO:0070573)
0.3 8.6 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.2 0.6 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.2 0.6 GO:0050508 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0050508)
0.2 0.5 GO:0008431 vitamin E binding(GO:0008431)
0.2 1.8 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.2 0.7 GO:0033765 steroid dehydrogenase activity, acting on the CH-CH group of donors(GO:0033765)
0.2 0.5 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.2 2.5 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 0.8 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.1 1.1 GO:0035727 lysophosphatidic acid binding(GO:0035727)
0.1 0.3 GO:0038132 neuregulin binding(GO:0038132)
0.1 1.3 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.1 0.9 GO:0043237 laminin-1 binding(GO:0043237)
0.1 2.4 GO:0017049 GTP-Rho binding(GO:0017049)
0.1 0.4 GO:0015199 amino-acid betaine transmembrane transporter activity(GO:0015199) carnitine transmembrane transporter activity(GO:0015226)
0.1 0.4 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.1 0.6 GO:0070728 leucine binding(GO:0070728)
0.1 0.3 GO:0004619 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.1 0.4 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.1 0.7 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.1 1.5 GO:0017166 vinculin binding(GO:0017166)
0.1 0.5 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.1 0.3 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.1 0.6 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.1 1.0 GO:0005549 odorant binding(GO:0005549)
0.1 0.3 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.1 1.6 GO:0035497 cAMP response element binding(GO:0035497)
0.1 0.5 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.1 0.4 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.1 1.7 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 1.1 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.1 0.4 GO:0008381 mechanically-gated ion channel activity(GO:0008381) mechanically gated channel activity(GO:0022833)
0.1 0.3 GO:0038181 bile acid receptor activity(GO:0038181)
0.1 0.2 GO:0042015 interleukin-20 binding(GO:0042015)
0.1 1.2 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.1 0.8 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.1 0.8 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.0 1.6 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.5 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 1.1 GO:0017160 Ral GTPase binding(GO:0017160)
0.0 0.4 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.0 0.9 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.4 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.6 GO:0005243 gap junction channel activity(GO:0005243)
0.0 1.0 GO:0005521 lamin binding(GO:0005521)
0.0 0.2 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.0 0.2 GO:0047276 N-acetyllactosaminide 3-alpha-galactosyltransferase activity(GO:0047276)
0.0 1.0 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 0.2 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.5 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.5 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 0.3 GO:0034711 inhibin binding(GO:0034711)
0.0 0.9 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.4 GO:0038191 neuropilin binding(GO:0038191)
0.0 0.5 GO:0030957 Tat protein binding(GO:0030957)
0.0 0.8 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.3 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 2.6 GO:0005254 chloride channel activity(GO:0005254)
0.0 0.7 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 1.0 GO:0050681 androgen receptor binding(GO:0050681)
0.0 1.2 GO:0043027 cysteine-type endopeptidase inhibitor activity involved in apoptotic process(GO:0043027)
0.0 0.3 GO:0032050 clathrin heavy chain binding(GO:0032050)
0.0 0.8 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.1 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.0 0.4 GO:0004869 cysteine-type endopeptidase inhibitor activity(GO:0004869)
0.0 0.1 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.0 1.5 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 0.2 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 1.8 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.6 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.9 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.2 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.2 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.0 0.1 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.0 0.2 GO:0043495 protein anchor(GO:0043495)
0.0 0.2 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.2 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.0 0.2 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.3 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.2 GO:0044548 S100 protein binding(GO:0044548)
0.0 1.9 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.1 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.3 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 1.6 GO:0008083 growth factor activity(GO:0008083)
0.0 0.6 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.8 ST STAT3 PATHWAY STAT3 Pathway
0.1 7.2 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.1 2.2 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.1 1.0 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 1.1 PID IL27 PATHWAY IL27-mediated signaling events
0.0 1.3 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 1.2 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.8 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.4 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.0 1.1 PID RHOA PATHWAY RhoA signaling pathway
0.0 0.6 PID ARF 3PATHWAY Arf1 pathway
0.0 1.1 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.3 PID AP1 PATHWAY AP-1 transcription factor network
0.0 0.1 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 0.1 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 1.8 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.4 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.0 0.7 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.7 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 0.4 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 0.5 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.3 PID ARF6 PATHWAY Arf6 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.9 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.2 7.8 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.1 3.1 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 2.0 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1 1.5 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 0.6 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.1 2.1 REACTOME GRB2 EVENTS IN ERBB2 SIGNALING Genes involved in GRB2 events in ERBB2 signaling
0.1 1.6 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.1 1.2 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.1 1.1 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.1 0.9 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.1 3.1 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.9 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.7 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.0 0.4 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.0 0.9 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.8 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.5 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 24 HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 24-hydroxycholesterol
0.0 0.6 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.1 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.4 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 1.0 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.0 0.4 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.0 1.0 REACTOME NETRIN1 SIGNALING Genes involved in Netrin-1 signaling
0.0 0.3 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.2 REACTOME ANDROGEN BIOSYNTHESIS Genes involved in Androgen biosynthesis
0.0 0.6 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.6 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.7 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.3 REACTOME DOWNREGULATION OF ERBB2 ERBB3 SIGNALING Genes involved in Downregulation of ERBB2:ERBB3 signaling
0.0 0.8 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.5 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.2 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0 0.6 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 0.9 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 1.0 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.3 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.5 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.4 REACTOME HS GAG BIOSYNTHESIS Genes involved in HS-GAG biosynthesis
0.0 1.6 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors