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2D miR_HR1_12

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Results for Nr4a2

Z-value: 0.82

Motif logo

Transcription factors associated with Nr4a2

Gene Symbol Gene ID Gene Info
ENSMUSG00000026826.7 nuclear receptor subfamily 4, group A, member 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Nr4a2mm10_v2_chr2_-_57124003_57124071-0.801.7e-03Click!

Activity profile of Nr4a2 motif

Sorted Z-values of Nr4a2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr2_-_129699833 3.81 ENSMUST00000028883.5
prodynorphin
chr11_-_109722214 1.81 ENSMUST00000020938.7
family with sequence similarity 20, member A
chr17_+_70522083 1.47 ENSMUST00000148486.1
ENSMUST00000133717.1
discs, large (Drosophila) homolog-associated protein 1
chr2_+_30595037 1.10 ENSMUST00000102853.3
CSA-conditional, T cell activation-dependent protein
chr6_+_96113146 1.03 ENSMUST00000122120.1
family with sequence similarity 19, member A1
chr3_+_89436699 0.95 ENSMUST00000038942.3
ENSMUST00000130858.1
pre B cell leukemia transcription factor interacting protein 1
chr9_+_108392820 0.93 ENSMUST00000035234.4
RIKEN cDNA 1700102P08 gene
chr9_-_22002599 0.93 ENSMUST00000115336.2
ENSMUST00000044926.5
coiled-coil domain containing 151
chr5_-_67099235 0.84 ENSMUST00000012664.8
paired-like homeobox 2b
chr3_+_89436736 0.83 ENSMUST00000146630.1
ENSMUST00000145753.1
pre B cell leukemia transcription factor interacting protein 1
chr17_+_69439326 0.80 ENSMUST00000169935.1
RIKEN cDNA A330050F15 gene
chr5_+_102845007 0.77 ENSMUST00000070000.4
Rho GTPase activating protein 24
chr13_-_92131494 0.75 ENSMUST00000099326.3
ENSMUST00000146492.1
RAS protein-specific guanine nucleotide-releasing factor 2
chr7_+_4119556 0.74 ENSMUST00000079415.5
tweety homolog 1 (Drosophila)
chr7_+_4119525 0.73 ENSMUST00000119661.1
ENSMUST00000129423.1
tweety homolog 1 (Drosophila)
chr10_-_20725023 0.72 ENSMUST00000020165.7
phosphodiesterase 7B
chr2_+_132781278 0.64 ENSMUST00000028826.3
chromogranin B
chr2_-_59160644 0.61 ENSMUST00000077687.5
coiled-coil domain containing 148
chr7_+_102267795 0.60 ENSMUST00000033289.4
stromal interaction molecule 1
chr3_-_108086590 0.60 ENSMUST00000102638.1
ENSMUST00000102637.1
adenosine monophosphate deaminase 2
chr16_-_20426322 0.58 ENSMUST00000115547.2
ENSMUST00000096199.4
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
chr6_-_138422898 0.57 ENSMUST00000161450.1
ENSMUST00000163024.1
ENSMUST00000162185.1
LIM domain only 3
chr3_-_20275659 0.56 ENSMUST00000011607.5
carboxypeptidase B1 (tissue)
chr1_-_124045247 0.55 ENSMUST00000112603.2
dipeptidylpeptidase 10
chr19_+_43782181 0.51 ENSMUST00000026208.4
ATP-binding cassette, sub-family C (CFTR/MRP), member 2
chr9_+_22003035 0.51 ENSMUST00000115331.2
ENSMUST00000003493.7
protein kinase C substrate 80K-H
chr13_+_74121435 0.50 ENSMUST00000036208.6
solute carrier family 9 (sodium/hydrogen exchanger), member 3
chr10_-_42478280 0.50 ENSMUST00000151747.1
lactation elevated 1
chr17_-_35909626 0.50 ENSMUST00000141132.1
alpha tubulin acetyltransferase 1
chr8_-_84044982 0.50 ENSMUST00000061923.4
relaxin 3
chr1_-_87573825 0.49 ENSMUST00000068681.5
neuronal guanine nucleotide exchange factor
chr16_-_20426375 0.49 ENSMUST00000079158.6
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
chr15_+_54952939 0.47 ENSMUST00000181704.1
predicted gene, 26684
chr5_-_137613759 0.43 ENSMUST00000155251.1
ENSMUST00000124693.1
procollagen C-endopeptidase enhancer protein
chr1_+_182409162 0.42 ENSMUST00000117245.1
transformation related protein 53 binding protein 2
chr19_-_45998479 0.42 ENSMUST00000045396.7
RIKEN cDNA 9130011E15 gene
chr8_-_13494479 0.42 ENSMUST00000033828.5
growth arrest specific 6
chr16_+_8830093 0.42 ENSMUST00000023150.5
RIKEN cDNA 1810013L24 gene
chr19_-_32061438 0.41 ENSMUST00000096119.4
N-acylsphingosine amidohydrolase 2
chr11_+_70657687 0.41 ENSMUST00000134087.1
ENSMUST00000170716.1
enolase 3, beta muscle
chr5_+_52363925 0.41 ENSMUST00000101208.4
superoxide dismutase 3, extracellular
chr15_-_42676967 0.40 ENSMUST00000022921.5
angiopoietin 1
chr7_+_105554360 0.39 ENSMUST00000046983.8
sphingomyelin phosphodiesterase 1, acid lysosomal
chr17_-_35910032 0.38 ENSMUST00000141662.1
ENSMUST00000056034.6
ENSMUST00000077494.6
ENSMUST00000149277.1
ENSMUST00000061052.5
alpha tubulin acetyltransferase 1
chr11_-_61494173 0.37 ENSMUST00000101085.2
ENSMUST00000079080.6
ENSMUST00000108714.1
mitogen-activated protein kinase 7
chr7_-_100514800 0.37 ENSMUST00000054923.7
DnaJ (Hsp40) related, subfamily B, member 13
chr7_-_141429433 0.35 ENSMUST00000124444.1
cell cycle exit and neuronal differentiation 1
chr3_-_144932523 0.33 ENSMUST00000098549.3
expressed sequence AI747448
chr15_+_35296090 0.33 ENSMUST00000022952.4
odd-skipped related 2
chr5_-_66151903 0.32 ENSMUST00000167950.1
RNA binding motif protein 47
chr4_+_136357423 0.32 ENSMUST00000182167.1
predicted gene, 17388
chr6_+_92091378 0.31 ENSMUST00000113460.1
nuclear receptor subfamily 2, group C, member 2
chr11_-_79504078 0.31 ENSMUST00000164465.2
oligodendrocyte myelin glycoprotein
chr9_+_118506226 0.31 ENSMUST00000084820.4
golgi autoantigen, golgin subfamily a, 4
chr9_+_98864767 0.31 ENSMUST00000167951.1
RIKEN cDNA 2410012M07 gene
chr5_+_63649335 0.31 ENSMUST00000159584.1
RIKEN cDNA 3110047P20 gene
chr2_+_61593125 0.31 ENSMUST00000112494.1
TRAF family member-associated Nf-kappa B activator
chr4_-_42528175 0.30 ENSMUST00000180201.1
predicted gene 13298
chr2_+_61593077 0.30 ENSMUST00000112495.1
ENSMUST00000112501.2
TRAF family member-associated Nf-kappa B activator
chr10_+_42502197 0.30 ENSMUST00000105499.1
sorting nexin 3
chr5_-_31202215 0.29 ENSMUST00000176245.1
ENSMUST00000177310.1
ENSMUST00000114590.1
zinc finger protein 513
chr19_+_46152505 0.29 ENSMUST00000026254.7
golgi-specific brefeldin A-resistance factor 1
chr4_-_42853888 0.27 ENSMUST00000107979.1
predicted gene 12429
chr8_-_64733534 0.26 ENSMUST00000141021.1
sterol-C4-methyl oxidase-like
chr4_-_141623799 0.25 ENSMUST00000038661.7
solute carrier family 25, member 34
chr1_-_167393826 0.25 ENSMUST00000028005.2
microsomal glutathione S-transferase 3
chr7_-_141429351 0.25 ENSMUST00000164387.1
ENSMUST00000137488.1
ENSMUST00000084436.3
cell cycle exit and neuronal differentiation 1
chr11_-_100822525 0.25 ENSMUST00000107358.2
signal transducer and activator of transcription 5B
chr9_-_32344237 0.24 ENSMUST00000034533.5
potassium inwardly-rectifying channel, subfamily J, member 5
chr11_-_69948145 0.23 ENSMUST00000179298.1
ENSMUST00000018710.6
ENSMUST00000135437.1
ENSMUST00000141837.2
ENSMUST00000142500.1
solute carrier family 2 (facilitated glucose transporter), member 4
chr1_+_167618246 0.23 ENSMUST00000111380.1
retinoid X receptor gamma
chr7_-_19950729 0.22 ENSMUST00000043440.6
immunoglobulin superfamily, member 23
chr10_-_20724696 0.20 ENSMUST00000170265.1
phosphodiesterase 7B
chr2_-_73892619 0.20 ENSMUST00000112007.1
ENSMUST00000112016.2
activating transcription factor 2
chrX_+_160768179 0.20 ENSMUST00000112368.2
retinoschisis (X-linked, juvenile) 1 (human)
chr2_-_73892588 0.20 ENSMUST00000154456.1
ENSMUST00000090802.4
ENSMUST00000055833.5
activating transcription factor 2
chr15_-_89425856 0.19 ENSMUST00000109313.2
carnitine palmitoyltransferase 1b, muscle
chr10_-_42478488 0.19 ENSMUST00000041024.8
lactation elevated 1
chr8_+_104847061 0.19 ENSMUST00000055052.5
carboxylesterase 2C
chr15_-_68363139 0.18 ENSMUST00000175699.1
predicted gene 20732
chr16_-_44139630 0.17 ENSMUST00000137557.1
ENSMUST00000147025.1
ATPase, H+ transporting, lysosomal V1 subunit A
chr11_+_121702591 0.16 ENSMUST00000125580.1
meteorin, glial cell differentiation regulator-like
chr5_-_67099045 0.16 ENSMUST00000174251.1
paired-like homeobox 2b
chr17_-_43667015 0.16 ENSMUST00000024705.4
solute carrier family 25, member 27
chr9_-_64737684 0.16 ENSMUST00000171100.1
ENSMUST00000167569.1
ENSMUST00000004892.6
ENSMUST00000172298.1
RAB11a, member RAS oncogene family
chr3_+_122895072 0.16 ENSMUST00000023820.5
fatty acid binding protein 2, intestinal
chr8_+_68880491 0.15 ENSMUST00000015712.8
lipoprotein lipase
chr17_+_47737030 0.15 ENSMUST00000086932.3
transcription factor EB
chr11_+_70657196 0.15 ENSMUST00000157027.1
ENSMUST00000072841.5
ENSMUST00000108548.1
ENSMUST00000126241.1
enolase 3, beta muscle
chr13_-_17805093 0.15 ENSMUST00000042365.7
cyclin-dependent kinase 13
chr2_-_13491900 0.15 ENSMUST00000091436.5
cubilin (intrinsic factor-cobalamin receptor)
chr18_+_65582390 0.15 ENSMUST00000169679.1
ENSMUST00000183326.1
zinc finger protein 532
chr15_-_89425795 0.14 ENSMUST00000168376.1
carnitine palmitoyltransferase 1b, muscle
chr11_+_96323253 0.14 ENSMUST00000093944.3
homeobox B3
chr5_-_66151323 0.14 ENSMUST00000131838.1
RNA binding motif protein 47
chr2_+_173153048 0.14 ENSMUST00000029017.5
phosphoenolpyruvate carboxykinase 1, cytosolic
chr2_-_73892530 0.14 ENSMUST00000136958.1
ENSMUST00000112010.2
ENSMUST00000128531.1
ENSMUST00000112017.1
activating transcription factor 2
chr1_-_24100306 0.13 ENSMUST00000027337.8
family with sequence similarity 135, member A
chr3_+_95134088 0.12 ENSMUST00000066386.5
LysM, putative peptidoglycan-binding, domain containing 1
chr3_-_95133989 0.12 ENSMUST00000172572.2
ENSMUST00000173462.2
sodium channel modifier 1
chr18_+_36664060 0.12 ENSMUST00000036765.7
eukaryotic translation initiation factor 4E binding protein 3
chr19_-_8405060 0.12 ENSMUST00000064507.5
ENSMUST00000120540.1
ENSMUST00000096269.4
solute carrier family 22, member 30
chr1_+_57845534 0.11 ENSMUST00000169772.1
spermatogenesis associated, serine-rich 2-like
chr12_+_4082574 0.10 ENSMUST00000020986.7
DnaJ (Hsp40) homolog, subfamily C, member 27
chr9_-_64737623 0.10 ENSMUST00000169058.1
RAB11a, member RAS oncogene family
chr5_-_121527186 0.10 ENSMUST00000152270.1
MAP kinase-activated protein kinase 5
chr16_-_44139196 0.09 ENSMUST00000063661.6
ENSMUST00000114666.2
ATPase, H+ transporting, lysosomal V1 subunit A
chr4_-_36136463 0.08 ENSMUST00000098151.2
leucine rich repeat and Ig domain containing 2
chr19_+_3767953 0.08 ENSMUST00000113970.1
suppressor of variegation 4-20 homolog 1 (Drosophila)
chrX_+_152233228 0.08 ENSMUST00000112588.2
ENSMUST00000082177.6
lysine (K)-specific demethylase 5C
chr18_+_86711059 0.08 ENSMUST00000068423.3
cerebellin 2 precursor protein
chr3_-_88027465 0.08 ENSMUST00000005014.2
hyaluronan and proteoglycan link protein 2
chr7_+_125603420 0.08 ENSMUST00000033000.6
interleukin 21 receptor
chr2_+_144033059 0.08 ENSMUST00000037722.2
ENSMUST00000110032.1
barrier to autointegration factor 2
chr2_+_79707780 0.08 ENSMUST00000090760.2
ENSMUST00000040863.4
ENSMUST00000111780.2
protein phosphatase 1, regulatory (inhibitor) subunit 1C
chr2_-_26237368 0.07 ENSMUST00000036187.8
quiescin Q6 sulfhydryl oxidase 2
chr10_+_53337686 0.07 ENSMUST00000046221.6
ENSMUST00000163319.1
phospholamban
chr2_+_105668888 0.07 ENSMUST00000111086.4
ENSMUST00000111087.3
paired box gene 6
chr19_+_36554661 0.07 ENSMUST00000169036.2
ENSMUST00000047247.5
HECT domain containing 2
chr6_-_59024470 0.07 ENSMUST00000089860.5
family with sequence similarity 13, member A
chr2_+_105668935 0.06 ENSMUST00000142772.1
paired box gene 6
chr4_+_102760135 0.06 ENSMUST00000066824.7
SH3-domain GRB2-like (endophilin) interacting protein 1
chr4_+_150914562 0.05 ENSMUST00000135169.1
tumor necrosis factor receptor superfamily, member 9
chr4_+_99955715 0.04 ENSMUST00000102783.4
phosphoglucomutase 2
chr19_+_3768112 0.04 ENSMUST00000005518.9
ENSMUST00000113967.1
ENSMUST00000152935.1
ENSMUST00000176262.1
ENSMUST00000176407.1
ENSMUST00000176926.1
ENSMUST00000176512.1
suppressor of variegation 4-20 homolog 1 (Drosophila)
chr4_+_102760294 0.04 ENSMUST00000072481.5
ENSMUST00000156596.1
ENSMUST00000080728.6
ENSMUST00000106882.2
SH3-domain GRB2-like (endophilin) interacting protein 1
chr9_-_42461414 0.04 ENSMUST00000066179.7
tubulin folding cofactor E-like
chrX_+_49463926 0.03 ENSMUST00000130558.1
Rho GTPase activating protein 36
chr11_-_70656467 0.03 ENSMUST00000131642.1
predicted gene 12319
chr6_-_99096196 0.03 ENSMUST00000175886.1
forkhead box P1
chr18_+_57142782 0.02 ENSMUST00000139892.1
multiple EGF-like-domains 10
chrX_+_160768013 0.02 ENSMUST00000033650.7
retinoschisis (X-linked, juvenile) 1 (human)
chr10_-_117224480 0.02 ENSMUST00000020382.6
YEATS domain containing 4
chr6_+_113697050 0.02 ENSMUST00000089018.4
TatD DNase domain containing 2
chr2_+_158794807 0.01 ENSMUST00000029186.7
ENSMUST00000109478.2
ENSMUST00000156893.1
DEAH (Asp-Glu-Ala-His) box polypeptide 35
chr8_-_119840522 0.01 ENSMUST00000168698.1
ENSMUST00000034285.6
coactosin-like 1 (Dictyostelium)
chr6_-_125236996 0.00 ENSMUST00000032486.6
CD27 antigen
chr2_-_101621033 0.00 ENSMUST00000090513.4
RIKEN cDNA B230118H07 gene

Network of associatons between targets according to the STRING database.

First level regulatory network of Nr4a2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0021934 hindbrain tangential cell migration(GO:0021934)
0.3 0.9 GO:0071929 alpha-tubulin acetylation(GO:0071929)
0.2 2.4 GO:0070166 enamel mineralization(GO:0070166)
0.2 0.6 GO:0021933 radial glia guided migration of cerebellar granule cell(GO:0021933) negative regulation of cerebellar granule cell precursor proliferation(GO:0021941)
0.2 0.6 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.1 0.4 GO:0030210 heparin biosynthetic process(GO:0030210)
0.1 0.4 GO:0070375 ERK5 cascade(GO:0070375)
0.1 1.5 GO:0070842 aggresome assembly(GO:0070842)
0.1 0.4 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.1 0.5 GO:0032915 positive regulation of transforming growth factor beta2 production(GO:0032915)
0.1 0.4 GO:0003104 positive regulation of glomerular filtration(GO:0003104)
0.1 0.3 GO:2000642 intralumenal vesicle formation(GO:0070676) negative regulation of early endosome to late endosome transport(GO:2000642)
0.1 0.3 GO:0035964 COPI-coated vesicle budding(GO:0035964) protein localization to endoplasmic reticulum exit site(GO:0070973)
0.1 0.8 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.1 0.3 GO:0036022 limb joint morphogenesis(GO:0036022) embryonic skeletal limb joint morphogenesis(GO:0036023)
0.1 0.6 GO:0032264 IMP salvage(GO:0032264)
0.1 0.5 GO:0015722 canalicular bile acid transport(GO:0015722)
0.1 0.4 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.1 0.3 GO:0010796 regulation of multivesicular body size(GO:0010796)
0.1 0.9 GO:0036158 outer dynein arm assembly(GO:0036158)
0.1 3.8 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.1 0.2 GO:0036367 adaptation of rhodopsin mediated signaling(GO:0016062) light adaption(GO:0036367)
0.0 0.5 GO:0061002 negative regulation of dendritic spine morphogenesis(GO:0061002)
0.0 0.1 GO:0006114 glycerol biosynthetic process(GO:0006114) positive regulation of transcription from RNA polymerase II promoter in response to acidic pH(GO:0061402)
0.0 0.5 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.2 GO:0046544 development of secondary male sexual characteristics(GO:0046544) response to interleukin-15(GO:0070672)
0.0 0.2 GO:0051562 negative regulation of mitochondrial calcium ion concentration(GO:0051562)
0.0 0.5 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.2 GO:0009816 defense response to bacterium, incompatible interaction(GO:0009816) regulation of defense response to bacterium, incompatible interaction(GO:1902477)
0.0 0.2 GO:1990573 membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914) potassium ion import across plasma membrane(GO:1990573)
0.0 0.2 GO:0055095 lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096)
0.0 1.5 GO:1902476 chloride transmembrane transport(GO:1902476)
0.0 0.1 GO:0021917 pancreatic A cell development(GO:0003322) forebrain-midbrain boundary formation(GO:0021905) somatic motor neuron fate commitment(GO:0021917) regulation of transcription from RNA polymerase II promoter involved in somatic motor neuron fate commitment(GO:0021918) sensory neuron migration(GO:1904937)
0.0 0.1 GO:0015889 cobalamin transport(GO:0015889)
0.0 0.5 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.1 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
0.0 0.3 GO:2000507 positive regulation of energy homeostasis(GO:2000507)
0.0 0.4 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.0 0.1 GO:0008065 establishment of blood-nerve barrier(GO:0008065)
0.0 0.4 GO:2000310 regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310)
0.0 0.3 GO:0048520 positive regulation of behavior(GO:0048520)
0.0 0.1 GO:0015747 urate transport(GO:0015747)
0.0 0.3 GO:0036295 cellular response to increased oxygen levels(GO:0036295)
0.0 0.3 GO:0022010 central nervous system myelination(GO:0022010) axon ensheathment in central nervous system(GO:0032291)
0.0 0.1 GO:0090400 stress-induced premature senescence(GO:0090400)
0.0 0.1 GO:0034720 histone H3-K4 demethylation(GO:0034720)
0.0 0.0 GO:2001183 negative regulation of interleukin-12 secretion(GO:2001183)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.5 GO:0097425 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.1 0.9 GO:0097427 microtubule bundle(GO:0097427)
0.1 0.6 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 0.6 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.5 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.3 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.1 GO:0043202 lysosomal lumen(GO:0043202)
0.0 0.4 GO:0042599 lamellar body(GO:0042599)
0.0 0.3 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.3 GO:0032009 early phagosome(GO:0032009)
0.0 3.9 GO:0043679 axon terminus(GO:0043679)
0.0 0.1 GO:0032156 septin cytoskeleton(GO:0032156)
0.0 0.2 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.1 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.0 0.5 GO:0035861 site of double-strand break(GO:0035861)
0.0 0.2 GO:0045179 apical cortex(GO:0045179)
0.0 1.3 GO:0005930 axoneme(GO:0005930)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.6 GO:0001515 opioid peptide activity(GO:0001515)
0.4 1.5 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.2 0.6 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.1 0.9 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.1 0.4 GO:0017040 ceramidase activity(GO:0017040)
0.1 0.4 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.1 0.2 GO:0086089 voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization(GO:0086089)
0.1 0.6 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 0.3 GO:0016416 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.1 0.6 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 0.4 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.1 1.8 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.5 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.6 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.2 GO:0055056 D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.5 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.5 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.1 GO:0030492 hemoglobin binding(GO:0030492)
0.0 0.4 GO:0005172 vascular endothelial growth factor receptor binding(GO:0005172)
0.0 0.9 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.4 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 0.2 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.0 0.4 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.2 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.0 0.6 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.4 GO:0004707 MAP kinase activity(GO:0004707)
0.0 0.1 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.0 0.3 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.1 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.1 GO:0032453 histone demethylase activity (H3-K4 specific)(GO:0032453)
0.0 0.1 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 1.1 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 0.3 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.2 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.5 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 0.3 PID ARF 3PATHWAY Arf1 pathway
0.0 0.6 PID CD8 TCR PATHWAY TCR signaling in naïve CD8+ T cells
0.0 0.1 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 0.4 PID TRAIL PATHWAY TRAIL signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.8 REACTOME G PROTEIN ACTIVATION Genes involved in G-protein activation
0.1 0.6 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.1 1.1 REACTOME HYALURONAN METABOLISM Genes involved in Hyaluronan metabolism
0.0 0.5 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.4 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.6 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.8 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0 0.5 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.6 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.3 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.4 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.2 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.2 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.5 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.1 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.3 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 0.3 REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0 0.2 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits