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2D miR_HR1_12

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Results for Gbx2

Z-value: 0.29

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Transcription factors associated with Gbx2

Gene Symbol Gene ID Gene Info
ENSMUSG00000034486.7 gastrulation brain homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Gbx2mm10_v2_chr1_-_89933290_899332900.019.7e-01Click!

Activity profile of Gbx2 motif

Sorted Z-values of Gbx2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr4_-_129261394 0.33 ENSMUST00000145261.1
expressed sequence C77080
chr19_-_32196393 0.20 ENSMUST00000151822.1
sphingomyelin synthase 1
chr7_-_141434402 0.20 ENSMUST00000136354.1
solute carrier family 25 (mitochondrial carrier, glutamate), member 22
chr12_+_79297345 0.19 ENSMUST00000079533.5
ENSMUST00000171210.1
RAD51 homolog B
chr3_+_94372794 0.19 ENSMUST00000029795.3
RAR-related orphan receptor gamma
chr19_+_23723279 0.18 ENSMUST00000067077.1
predicted gene 9938
chr16_-_36784784 0.18 ENSMUST00000165531.1
solute carrier family 15 (H+/peptide transporter), member 2
chr17_-_48432723 0.17 ENSMUST00000046549.3
apolipoprotein B mRNA editing enzyme, catalytic polypeptide 2
chr14_-_18893376 0.16 ENSMUST00000151926.1
ubiquitin-conjugating enzyme E2E 2
chr3_-_96452306 0.15 ENSMUST00000093126.4
ENSMUST00000098841.3
cDNA sequence BC107364
chr3_+_88615367 0.14 ENSMUST00000176539.1
rho/rac guanine nucleotide exchange factor (GEF) 2
chr1_-_155417394 0.14 ENSMUST00000111775.1
ENSMUST00000111774.1
xenotropic and polytropic retrovirus receptor 1
chr13_-_54399246 0.13 ENSMUST00000124238.1
predicted gene 16248
chr7_-_141434532 0.13 ENSMUST00000133021.1
ENSMUST00000106007.3
ENSMUST00000150026.1
ENSMUST00000133206.2
solute carrier family 25 (mitochondrial carrier, glutamate), member 22
chr7_-_30664986 0.09 ENSMUST00000019697.8
HAUS augmin-like complex, subunit 5
chr16_-_36784924 0.09 ENSMUST00000168279.1
ENSMUST00000164579.1
ENSMUST00000023616.2
solute carrier family 15 (H+/peptide transporter), member 2
chr4_-_26346882 0.08 ENSMUST00000041374.7
ENSMUST00000153813.1
mannosidase, endo-alpha
chr4_+_32657107 0.08 ENSMUST00000071642.4
ENSMUST00000178134.1
midasin homolog (yeast)
chr3_+_88616133 0.08 ENSMUST00000176500.1
ENSMUST00000177498.1
rho/rac guanine nucleotide exchange factor (GEF) 2
chr14_+_69347587 0.07 ENSMUST00000064831.5
ectonucleoside triphosphate diphosphohydrolase 4
chr11_-_5878207 0.07 ENSMUST00000102922.3
polymerase (DNA directed), delta 2, regulatory subunit
chrX_+_106920618 0.07 ENSMUST00000060576.7
lysophosphatidic acid receptor 4
chr1_-_4785671 0.07 ENSMUST00000130201.1
ENSMUST00000156816.1
mitochondrial ribosomal protein L15
chrM_+_14138 0.07 ENSMUST00000082421.1
mitochondrially encoded cytochrome b
chr16_-_26371828 0.07 ENSMUST00000023154.2
claudin 1
chrM_-_14060 0.06 ENSMUST00000082419.1
mitochondrially encoded NADH dehydrogenase 6
chr11_-_45955183 0.06 ENSMUST00000109254.1
tRNA-histidine guanylyltransferase 1-like (S. cerevisiae)
chr10_+_128083273 0.06 ENSMUST00000026459.5
ATP synthase, H+ transporting mitochondrial F1 complex, beta subunit
chrX_-_56598069 0.06 ENSMUST00000059899.2
membrane magnesium transporter 1
chr1_+_180109192 0.05 ENSMUST00000143176.1
ENSMUST00000135056.1
CDC42 binding protein kinase alpha
chr13_+_23763660 0.05 ENSMUST00000055770.1
histone cluster 1, H1a
chr7_+_75455534 0.04 ENSMUST00000147005.1
ENSMUST00000166315.1
A kinase (PRKA) anchor protein 13
chr10_-_116896879 0.04 ENSMUST00000048229.7
myelin regulatory factor-like
chr8_-_41041828 0.04 ENSMUST00000051379.7
mitochondrial tumor suppressor 1
chr10_+_116177351 0.04 ENSMUST00000155606.1
ENSMUST00000128399.1
protein tyrosine phosphatase, receptor type, R
chr3_+_57425314 0.04 ENSMUST00000029377.7
transmembrane 4 superfamily member 4
chr13_+_31806627 0.04 ENSMUST00000062292.2
forkhead box C1
chr19_+_38132767 0.04 ENSMUST00000025956.5
ENSMUST00000112329.1
phosphodiesterase 6C, cGMP specific, cone, alpha prime
chr5_-_115341142 0.04 ENSMUST00000139167.1
glutamyl-tRNA(Gln) amidotransferase, subunit C homolog (bacterial)
chr1_-_128102412 0.03 ENSMUST00000112538.1
ENSMUST00000086614.5
zinc finger, RAN-binding domain containing 3
chr3_+_96645579 0.03 ENSMUST00000119365.1
ENSMUST00000029744.5
integrin, alpha 10
chr11_+_97315716 0.03 ENSMUST00000019026.3
ENSMUST00000132168.1
mitochondrial ribosomal protein L45
chr3_+_152714094 0.03 ENSMUST00000159899.1
ENSMUST00000045029.8
phosphatidylinositol glycan anchor biosynthesis, class K
chr3_-_89998656 0.02 ENSMUST00000079724.4
HCLS1 associated X-1
chr2_-_73580288 0.02 ENSMUST00000028515.3
cholinergic receptor, nicotinic, alpha polypeptide 1 (muscle)
chr2_+_84988194 0.02 ENSMUST00000028466.5
proteoglycan 3
chr17_+_84956718 0.02 ENSMUST00000112305.3
protein phosphatase 1B, magnesium dependent, beta isoform
chr3_-_141982224 0.02 ENSMUST00000029948.8
bone morphogenetic protein receptor, type 1B
chr3_-_10331358 0.02 ENSMUST00000065938.8
ENSMUST00000118410.1
inositol (myo)-1(or 4)-monophosphatase 1
chr4_+_110397661 0.02 ENSMUST00000106589.2
ENSMUST00000106587.2
ENSMUST00000106591.1
ENSMUST00000106592.1
ATP/GTP binding protein-like 4
chr10_+_116177217 0.02 ENSMUST00000148731.1
protein tyrosine phosphatase, receptor type, R
chr9_-_57683644 0.02 ENSMUST00000034860.3
cytochrome P450, family 1, subfamily a, polypeptide 2
chr9_+_96258697 0.01 ENSMUST00000179416.1
transcription factor Dp 2
chr7_+_78783119 0.01 ENSMUST00000032840.4
mitochondrial ribosomal protein S11
chr5_+_115341225 0.01 ENSMUST00000031508.4
TP53 regulated inhibitor of apoptosis 1
chr10_-_95501921 0.01 ENSMUST00000075829.2
mitochondrial ribosomal protein L42
chr1_-_175625580 0.01 ENSMUST00000027810.7
fumarate hydratase 1
chr7_-_140822124 0.01 ENSMUST00000106052.1
ENSMUST00000080651.6
zinc finger protein 941
chr7_-_78783026 0.01 ENSMUST00000032841.5
mitochondrial ribosomal protein L46
chr12_-_98259416 0.01 ENSMUST00000021390.7
galactosylceramidase
chr18_+_57354733 0.00 ENSMUST00000025490.8
proline-rich coiled-coil 1
chr14_-_30353468 0.00 ENSMUST00000112249.1
calcium channel, voltage-dependent, L type, alpha 1D subunit
chr14_-_66213552 0.00 ENSMUST00000178730.1
PTK2 protein tyrosine kinase 2 beta
chr16_-_13730970 0.00 ENSMUST00000023364.6
phospholipase A2, group X
chr2_+_23207470 0.00 ENSMUST00000028113.3
ENSMUST00000114505.1
RIKEN cDNA 4931423N10 gene
chr5_-_5266038 0.00 ENSMUST00000115451.1
ENSMUST00000115452.1
ENSMUST00000131392.1
cyclin-dependent kinase 14
chr11_-_21370452 0.00 ENSMUST00000102875.4
UDP-glucose pyrophosphorylase 2

Network of associatons between targets according to the STRING database.

First level regulatory network of Gbx2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0042938 dipeptide transport(GO:0042938)
0.0 0.2 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.0 0.2 GO:0071802 negative regulation of podosome assembly(GO:0071802)
0.0 0.2 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.1 GO:1903348 positive regulation of bicellular tight junction assembly(GO:1903348)
0.0 0.2 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.2 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.2 GO:0072615 interleukin-17 secretion(GO:0072615)
0.0 0.1 GO:0072502 cellular phosphate ion homeostasis(GO:0030643) phosphate ion transmembrane transport(GO:0035435) cellular divalent inorganic anion homeostasis(GO:0072501) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0 0.0 GO:1902256 apoptotic process involved in outflow tract morphogenesis(GO:0003275) negative regulation of lymphangiogenesis(GO:1901491) regulation of apoptotic process involved in outflow tract morphogenesis(GO:1902256) response to chemokine(GO:1990868) cellular response to chemokine(GO:1990869)
0.0 0.1 GO:0033762 response to glucagon(GO:0033762)
0.0 0.0 GO:0036292 DNA rewinding(GO:0036292)
0.0 0.3 GO:0015813 L-glutamate transport(GO:0015813)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.0 0.1 GO:0097636 intrinsic component of autophagosome membrane(GO:0097636) integral component of autophagosome membrane(GO:0097637)
0.0 0.1 GO:0043625 delta DNA polymerase complex(GO:0043625)
0.0 0.2 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.1 GO:0070652 HAUS complex(GO:0070652)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0042936 dipeptide transporter activity(GO:0042936)
0.0 0.2 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.2 GO:0008142 oxysterol binding(GO:0008142)
0.0 0.1 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.0 0.2 GO:0004126 cytidine deaminase activity(GO:0004126)
0.0 0.2 GO:0042296 ISG15 transferase activity(GO:0042296)
0.0 0.2 GO:0000150 recombinase activity(GO:0000150)
0.0 0.3 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.0 0.1 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
0.0 0.1 GO:0043532 angiostatin binding(GO:0043532)
0.0 0.1 GO:0045134 uridine-diphosphatase activity(GO:0045134)
0.0 0.1 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)