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2D miR_HR1_12

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Results for Runx1

Z-value: 0.71

Motif logo

Transcription factors associated with Runx1

Gene Symbol Gene ID Gene Info
ENSMUSG00000022952.10 runt related transcription factor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Runx1mm10_v2_chr16_-_92697315_92697347-0.078.2e-01Click!

Activity profile of Runx1 motif

Sorted Z-values of Runx1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr5_-_92328068 1.23 ENSMUST00000113093.3
chemokine (C-X-C motif) ligand 9
chr8_-_109579056 1.16 ENSMUST00000074898.6
haptoglobin
chr13_+_49608030 1.13 ENSMUST00000021822.5
osteoglycin
chr1_-_164935522 1.03 ENSMUST00000027860.7
chemokine (C motif) ligand 1
chr5_+_104435112 0.81 ENSMUST00000031243.8
ENSMUST00000086833.6
ENSMUST00000112748.1
ENSMUST00000112746.1
ENSMUST00000145084.1
ENSMUST00000132457.1
secreted phosphoprotein 1
chr11_+_99041237 0.79 ENSMUST00000017637.6
insulin-like growth factor binding protein 4
chr14_-_121915774 0.68 ENSMUST00000055475.7
G protein-coupled receptor 18
chr3_-_96814518 0.56 ENSMUST00000047702.7
CD160 antigen
chr1_+_160044564 0.54 ENSMUST00000168359.1
RIKEN cDNA 4930523C07 gene
chr2_+_164948219 0.52 ENSMUST00000017881.2
matrix metallopeptidase 9
chr7_-_127137807 0.49 ENSMUST00000049931.5
sialophorin
chr1_-_193264006 0.49 ENSMUST00000161737.1
hydroxysteroid 11-beta dehydrogenase 1
chr11_+_95842283 0.49 ENSMUST00000107714.2
ENSMUST00000107711.1
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2
chr2_-_58160495 0.47 ENSMUST00000028175.6
cytohesin 1 interacting protein
chr11_-_53634698 0.45 ENSMUST00000020650.1
interleukin 13
chr17_-_34743849 0.45 ENSMUST00000069507.8
complement component 4B (Chido blood group)
chrX_-_8090442 0.44 ENSMUST00000033505.6
Wiskott-Aldrich syndrome homolog (human)
chr7_+_44572370 0.43 ENSMUST00000002274.8
napsin A aspartic peptidase
chr11_-_83649349 0.43 ENSMUST00000001008.5
chemokine (C-C motif) ligand 3
chr11_-_69895523 0.43 ENSMUST00000001631.6
ArfGAP with coiled-coil, ankyrin repeat and PH domains 1
chr11_-_97115327 0.43 ENSMUST00000001484.2
T-box 21
chr4_-_137409777 0.41 ENSMUST00000024200.6
predicted gene 13011
chr5_+_140607334 0.41 ENSMUST00000031555.1
LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr12_+_85686648 0.41 ENSMUST00000040536.5
basic leucine zipper transcription factor, ATF-like
chr3_-_88378699 0.39 ENSMUST00000098956.2
bone gamma-carboxyglutamate protein 2
chr3_+_103860265 0.38 ENSMUST00000029433.7
protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
chr11_-_79530569 0.38 ENSMUST00000103236.3
ENSMUST00000170799.1
ENSMUST00000170422.2
ecotropic viral integration site 2a
ecotropic viral integration site 2b
chr11_+_69966896 0.34 ENSMUST00000151515.1
claudin 7
chr19_+_56461629 0.34 ENSMUST00000178590.1
ENSMUST00000039666.6
pleckstrin homology domain containing, family S member 1
chr2_+_126034647 0.33 ENSMUST00000064794.7
fibroblast growth factor 7
chrX_-_101734125 0.32 ENSMUST00000056614.6
chemokine (C-X-C motif) receptor 3
chr16_-_88563166 0.32 ENSMUST00000049697.4
claudin 8
chr12_-_112860886 0.32 ENSMUST00000021729.7
G protein-coupled receptor 132
chr18_-_62179948 0.31 ENSMUST00000053640.3
adrenergic receptor, beta 2
chrX_-_57338598 0.30 ENSMUST00000033468.4
ENSMUST00000114736.1
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr1_-_138175283 0.30 ENSMUST00000182755.1
ENSMUST00000183262.1
ENSMUST00000027645.7
ENSMUST00000112036.2
ENSMUST00000182283.1
protein tyrosine phosphatase, receptor type, C
chr2_+_126034967 0.30 ENSMUST00000110442.1
fibroblast growth factor 7
chr11_-_52282564 0.28 ENSMUST00000086844.3
transcription factor 7, T cell specific
chr14_+_70774304 0.26 ENSMUST00000022698.7
docking protein 2
chr13_-_113100971 0.25 ENSMUST00000023897.5
granzyme A
chr11_+_87663087 0.25 ENSMUST00000165679.1
ring finger protein 43
chr1_-_140183283 0.25 ENSMUST00000111977.1
complement component factor h
chr19_+_8850785 0.22 ENSMUST00000096257.2
LRRN4 C-terminal like
chrX_+_107255878 0.21 ENSMUST00000101294.2
ENSMUST00000118820.1
ENSMUST00000120971.1
G protein-coupled receptor 174
chr1_+_171388954 0.21 ENSMUST00000056449.8
Rho GTPase activating protein 30
chr5_-_98030727 0.21 ENSMUST00000031281.9
anthrax toxin receptor 2
chr1_-_138175126 0.21 ENSMUST00000183301.1
protein tyrosine phosphatase, receptor type, C
chr19_-_10829856 0.20 ENSMUST00000174176.1
CD6 antigen
chr1_-_138175238 0.20 ENSMUST00000182536.1
protein tyrosine phosphatase, receptor type, C
chr15_-_66801577 0.20 ENSMUST00000168589.1
src-like adaptor
chr14_-_56262233 0.20 ENSMUST00000015581.4
granzyme B
chr6_-_136941494 0.19 ENSMUST00000111892.1
Rho, GDP dissociation inhibitor (GDI) beta
chr17_+_75178911 0.19 ENSMUST00000112514.1
latent transforming growth factor beta binding protein 1
chr15_+_9436028 0.19 ENSMUST00000042360.3
calcyphosine-like
chr2_+_163820832 0.18 ENSMUST00000029188.7
WNT1 inducible signaling pathway protein 2
chr17_+_75178797 0.17 ENSMUST00000112516.1
ENSMUST00000135447.1
latent transforming growth factor beta binding protein 1
chr6_-_38637220 0.17 ENSMUST00000096030.3
killer cell lectin-like receptor subfamily G, member 2
chr7_+_24370255 0.17 ENSMUST00000171904.1
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 4
chr10_-_40025253 0.17 ENSMUST00000163705.2
expressed sequence AI317395
chr1_-_140183404 0.16 ENSMUST00000066859.6
ENSMUST00000111976.2
complement component factor h
chr7_-_25132473 0.16 ENSMUST00000108418.4
ENSMUST00000108415.3
ENSMUST00000098679.3
ENSMUST00000175774.2
ENSMUST00000108417.3
ENSMUST00000108416.3
ENSMUST00000108414.1
ENSMUST00000108413.1
ENSMUST00000176408.1
POU domain, class 2, transcription factor 2
chr6_-_136941694 0.16 ENSMUST00000032344.5
Rho, GDP dissociation inhibitor (GDI) beta
chr16_-_85901118 0.15 ENSMUST00000023611.5
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 5 (aggrecanase-2)
chr2_+_32629467 0.15 ENSMUST00000068271.4
adenylate kinase 1
chr7_+_126584937 0.15 ENSMUST00000039522.6
apolipoprotein B receptor
chr18_-_38929148 0.14 ENSMUST00000134864.1
fibroblast growth factor 1
chr15_-_102722120 0.13 ENSMUST00000171838.1
calcium binding and coiled coil domain 1
chr1_+_40515362 0.12 ENSMUST00000027237.5
interleukin 18 receptor accessory protein
chr1_+_36307745 0.12 ENSMUST00000142319.1
ENSMUST00000097778.2
ENSMUST00000115031.1
ENSMUST00000115032.1
ENSMUST00000137906.1
ENSMUST00000115029.1
AT rich interactive domain 5A (MRF1-like)
chr19_+_5568002 0.12 ENSMUST00000096318.3
adaptor-related protein complex 5, beta 1 subunit
chr12_+_95692212 0.12 ENSMUST00000057324.3
fibronectin leucine rich transmembrane protein 2
chr16_-_38433145 0.12 ENSMUST00000002926.6
phospholipase A1 member A
chr5_-_75044562 0.12 ENSMUST00000075452.5
cysteine-rich hydrophobic domain 2
chr4_+_65124174 0.12 ENSMUST00000084501.3
pregnancy-associated plasma protein A
chr7_-_133708958 0.11 ENSMUST00000106146.1
uroporphyrinogen III synthase
chr3_+_96181151 0.11 ENSMUST00000035371.8
synaptic vesicle glycoprotein 2 a
chr17_+_34670535 0.11 ENSMUST00000168533.1
ENSMUST00000087399.4
tenascin XB
chr11_-_46389454 0.11 ENSMUST00000101306.3
IL2 inducible T cell kinase
chr12_-_25096080 0.11 ENSMUST00000020974.6
inhibitor of DNA binding 2
chr15_-_76090013 0.10 ENSMUST00000019516.4
nuclear receptor binding protein 2
chr3_-_59101810 0.10 ENSMUST00000085040.4
G protein-coupled receptor 171
chr15_-_102722150 0.10 ENSMUST00000023818.3
calcium binding and coiled coil domain 1
chr7_+_143005046 0.10 ENSMUST00000009396.6
tetraspanin 32
chr7_-_115824699 0.10 ENSMUST00000169129.1
SRY-box containing gene 6
chr1_+_60746358 0.10 ENSMUST00000027165.2
CD28 antigen
chr7_-_133709069 0.10 ENSMUST00000106145.3
uroporphyrinogen III synthase
chr15_-_101869695 0.10 ENSMUST00000087996.5
keratin 77
chr2_+_164460945 0.10 ENSMUST00000072452.4
SYS1 Golgi-localized integral membrane protein homolog (S. cerevisiae)
chr17_-_44814649 0.10 ENSMUST00000113571.3
runt related transcription factor 2
chr17_+_13061099 0.10 ENSMUST00000086787.4
ENSMUST00000116666.1
t-complex protein 10b
chr7_-_43533171 0.10 ENSMUST00000004728.5
ENSMUST00000039861.5
CD33 antigen
chr17_+_36958571 0.09 ENSMUST00000040177.6
Znrd1 antisense
chr15_-_78493607 0.09 ENSMUST00000163494.1
interleukin 2 receptor, beta chain
chr14_-_31640878 0.09 ENSMUST00000167066.1
ENSMUST00000127204.2
ENSMUST00000022437.8
2-hydroxyacyl-CoA lyase 1
chr4_+_56743406 0.09 ENSMUST00000095079.4
actin-like 7a
chr2_+_172393900 0.09 ENSMUST00000109136.2
Cas scaffolding protein family member 4
chr3_-_89093358 0.08 ENSMUST00000090929.5
ENSMUST00000052539.6
RUN and SH3 domain containing 1
chr2_+_18672384 0.08 ENSMUST00000171845.1
ENSMUST00000061158.4
COMM domain containing 3
chr11_+_116030304 0.08 ENSMUST00000021116.5
ENSMUST00000106452.1
unkempt homolog (Drosophila)
chr17_+_36958623 0.08 ENSMUST00000173814.1
Znrd1 antisense
chr2_-_52558539 0.08 ENSMUST00000102760.3
ENSMUST00000102761.2
calcium channel, voltage-dependent, beta 4 subunit
chr12_+_10390756 0.07 ENSMUST00000020947.5
retinol dehydrogenase 14 (all-trans and 9-cis)
chr15_-_103255433 0.07 ENSMUST00000075192.6
nuclear factor, erythroid derived 2
chr4_+_135120640 0.07 ENSMUST00000056977.7
runt related transcription factor 3
chrX_+_48623737 0.07 ENSMUST00000114936.1
solute carrier family 25 (mitochondrial carrier, brain), member 14
chr2_+_69135799 0.07 ENSMUST00000041865.7
nitric oxide synthase trafficker
chr16_+_25801907 0.07 ENSMUST00000040231.6
ENSMUST00000115306.1
ENSMUST00000115304.1
ENSMUST00000115305.1
transformation related protein 63
chr3_+_103020546 0.07 ENSMUST00000029446.8
cold shock domain containing E1, RNA binding
chr8_+_84125989 0.06 ENSMUST00000093380.4
podocan-like 1
chr3_+_3634145 0.06 ENSMUST00000108394.1
hepatocyte nuclear factor 4, gamma
chr16_+_32271468 0.06 ENSMUST00000093183.3
single-pass membrane protein with coiled-coil domains 1
chr2_+_172393794 0.06 ENSMUST00000099061.2
ENSMUST00000103073.2
Cas scaffolding protein family member 4
chr7_+_62376979 0.06 ENSMUST00000080403.5
melanoma antigen, family L, 2
chr17_+_7324646 0.05 ENSMUST00000095726.4
ENSMUST00000128533.1
ENSMUST00000129709.1
ENSMUST00000147803.1
ENSMUST00000140192.1
ENSMUST00000138222.1
ENSMUST00000144861.1
t-complex protein 10a
chr4_-_129573637 0.05 ENSMUST00000102596.1
lymphocyte protein tyrosine kinase
chr5_+_8893677 0.05 ENSMUST00000003717.8
ATP-binding cassette, sub-family B (MDR/TAP), member 4
chr2_+_37516618 0.05 ENSMUST00000065441.6
G protein-coupled receptor 21
chr19_+_6061176 0.05 ENSMUST00000162726.3
zinc finger, HIT domain containing 2
chr2_-_52335134 0.05 ENSMUST00000075301.3
nebulin
chr18_-_35649349 0.04 ENSMUST00000025211.4
marginal zone B and B1 cell-specific protein 1
chr8_+_109705549 0.04 ENSMUST00000034163.8
zinc finger protein 821
chr7_+_133709333 0.04 ENSMUST00000033282.4
BRCA2 and CDKN1A interacting protein
chr2_+_153918391 0.04 ENSMUST00000109760.1
BPI fold containing family B, member 3
chr16_-_95586585 0.04 ENSMUST00000077773.6
avian erythroblastosis virus E-26 (v-ets) oncogene related
chr11_-_69685537 0.03 ENSMUST00000018896.7
tumor necrosis factor (ligand) superfamily, member 13
chr3_-_88296838 0.03 ENSMUST00000010682.3
TSSK6 activating co-chaperone
chr3_-_88296979 0.03 ENSMUST00000107556.3
TSSK6 activating co-chaperone
chr7_-_133709051 0.03 ENSMUST00000124759.1
ENSMUST00000106144.1
uroporphyrinogen III synthase
chr8_-_95434869 0.03 ENSMUST00000034249.6
gene trap locus 3
chr2_-_26021532 0.03 ENSMUST00000136750.1
ubiquitin associated domain containing 1
chr19_+_5050807 0.03 ENSMUST00000025818.6
Ras and Rab interactor 1
chr18_+_77773956 0.03 ENSMUST00000114748.1
ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1
chr1_-_168431896 0.03 ENSMUST00000176540.1
pre B cell leukemia homeobox 1
chr17_+_4994904 0.03 ENSMUST00000092723.4
ENSMUST00000115797.2
AT rich interactive domain 1B (SWI-like)
chr11_-_46389509 0.02 ENSMUST00000020664.6
IL2 inducible T cell kinase
chr8_+_76902277 0.02 ENSMUST00000109912.1
ENSMUST00000128862.1
ENSMUST00000109911.1
nuclear receptor subfamily 3, group C, member 2
chr1_-_161788489 0.02 ENSMUST00000000834.2
Fas ligand (TNF superfamily, member 6)
chr4_-_46404224 0.02 ENSMUST00000107764.2
hemogen
chrX_+_56913421 0.02 ENSMUST00000168724.1
G protein-coupled receptor 112
chr1_+_34160253 0.02 ENSMUST00000183302.1
dystonin
chr11_-_46389471 0.02 ENSMUST00000109237.2
IL2 inducible T cell kinase
chr4_-_14621494 0.02 ENSMUST00000149633.1
solute carrier family 26, member 7
chr17_+_12119274 0.02 ENSMUST00000024594.2
1-acylglycerol-3-phosphate O-acyltransferase 4 (lysophosphatidic acid acyltransferase, delta)
chr2_-_26021679 0.02 ENSMUST00000036509.7
ubiquitin associated domain containing 1
chr2_+_32721055 0.01 ENSMUST00000074248.4
SH2 domain containing 3C
chr1_-_169747634 0.01 ENSMUST00000027991.5
ENSMUST00000111357.1
regulator of G-protein signaling 4
chr16_+_43510267 0.01 ENSMUST00000114695.2
zinc finger and BTB domain containing 20
chr3_+_103058302 0.01 ENSMUST00000029445.6
neuroblastoma ras oncogene
chr1_+_128244122 0.01 ENSMUST00000027592.3
UBX domain protein 4
chr9_-_70934808 0.01 ENSMUST00000034731.8
lipase, hepatic
chr7_-_126584220 0.01 ENSMUST00000128970.1
ENSMUST00000116269.2
ceroid lipofuscinosis, neuronal 3, juvenile (Batten, Spielmeyer-Vogt disease)
chr11_-_101095367 0.01 ENSMUST00000019447.8
proteasome (prosome, macropain) 26S subunit, ATPase 3, interacting protein
chr9_-_107770945 0.01 ENSMUST00000183248.1
ENSMUST00000182022.1
ENSMUST00000035199.6
ENSMUST00000182659.1
RNA binding motif protein 5
chr8_-_11008458 0.01 ENSMUST00000040514.6
insulin receptor substrate 2
chr15_-_34356421 0.00 ENSMUST00000179647.1
RIKEN cDNA 9430069I07 gene
chr15_-_97844164 0.00 ENSMUST00000120683.1
histone deacetylase 7
chr15_+_80711292 0.00 ENSMUST00000067689.7
trinucleotide repeat containing 6b
chr2_+_79707780 0.00 ENSMUST00000090760.2
ENSMUST00000040863.4
ENSMUST00000111780.2
protein phosphatase 1, regulatory (inhibitor) subunit 1C

Network of associatons between targets according to the STRING database.

First level regulatory network of Runx1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0071663 granzyme B production(GO:0071613) regulation of granzyme B production(GO:0071661) positive regulation of granzyme B production(GO:0071663)
0.4 1.2 GO:2000295 regulation of hydrogen peroxide catabolic process(GO:2000295)
0.3 0.8 GO:0006710 androgen catabolic process(GO:0006710) estradiol secretion(GO:0035938) regulation of estradiol secretion(GO:2000864)
0.2 0.7 GO:0002304 gamma-delta intraepithelial T cell differentiation(GO:0002304) CD8-positive, gamma-delta intraepithelial T cell differentiation(GO:0002305)
0.2 0.6 GO:0061033 secretion by lung epithelial cell involved in lung growth(GO:0061033)
0.2 0.5 GO:0001806 type IV hypersensitivity(GO:0001806) negative regulation of hypersensitivity(GO:0002884)
0.2 0.5 GO:0006713 glucocorticoid catabolic process(GO:0006713)
0.2 0.5 GO:1903660 negative regulation of NAD(P)H oxidase activity(GO:0033861) pancreatic stellate cell proliferation(GO:0072343) regulation of complement-dependent cytotoxicity(GO:1903659) negative regulation of complement-dependent cytotoxicity(GO:1903660) regulation of pancreatic stellate cell proliferation(GO:2000229)
0.1 0.7 GO:0002378 immunoglobulin biosynthetic process(GO:0002378)
0.1 0.3 GO:0003099 positive regulation of the force of heart contraction by epinephrine-norepinephrine(GO:0001997) positive regulation of the force of heart contraction by chemical signal(GO:0003099)
0.1 0.4 GO:0007386 compartment pattern specification(GO:0007386)
0.1 0.5 GO:1900122 positive regulation of receptor binding(GO:1900122)
0.1 0.4 GO:0002457 T cell antigen processing and presentation(GO:0002457)
0.1 0.4 GO:0045919 positive regulation of cytolysis(GO:0045919)
0.1 1.6 GO:0010818 T cell chemotaxis(GO:0010818)
0.1 0.2 GO:0006780 uroporphyrinogen III biosynthetic process(GO:0006780)
0.1 0.1 GO:2000554 regulation of T-helper 1 cell cytokine production(GO:2000554) positive regulation of T-helper 1 cell cytokine production(GO:2000556)
0.0 0.8 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.0 0.5 GO:0048304 positive regulation of isotype switching to IgG isotypes(GO:0048304)
0.0 0.4 GO:0043615 astrocyte cell migration(GO:0043615)
0.0 0.3 GO:1901164 negative regulation of trophoblast cell migration(GO:1901164)
0.0 0.3 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.0 0.2 GO:0008626 granzyme-mediated apoptotic signaling pathway(GO:0008626)
0.0 0.4 GO:0043129 surfactant homeostasis(GO:0043129)
0.0 0.3 GO:0002568 somatic diversification of T cell receptor genes(GO:0002568) somatic recombination of T cell receptor gene segments(GO:0002681) T cell receptor V(D)J recombination(GO:0033153)
0.0 0.1 GO:1901509 regulation of endothelial tube morphogenesis(GO:1901509)
0.0 0.0 GO:0048298 positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.0 0.3 GO:0032074 negative regulation of nuclease activity(GO:0032074)
0.0 0.4 GO:0072540 T-helper 17 cell lineage commitment(GO:0072540)
0.0 0.1 GO:0003166 bundle of His development(GO:0003166) epithelial cell differentiation involved in mammary gland alveolus development(GO:0061030)
0.0 0.2 GO:0006172 ADP biosynthetic process(GO:0006172)
0.0 0.1 GO:0048807 female genitalia morphogenesis(GO:0048807) cloacal septation(GO:0060197)
0.0 0.3 GO:0032463 negative regulation of protein homooligomerization(GO:0032463)
0.0 0.1 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.0 0.1 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.0 0.2 GO:0046541 saliva secretion(GO:0046541)
0.0 0.4 GO:0044342 type B pancreatic cell proliferation(GO:0044342)
0.0 0.1 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.0 0.4 GO:0032967 positive regulation of collagen biosynthetic process(GO:0032967)
0.0 0.1 GO:0030886 negative regulation of myeloid dendritic cell activation(GO:0030886)
0.0 0.2 GO:0015812 gamma-aminobutyric acid secretion(GO:0014051) gamma-aminobutyric acid transport(GO:0015812)
0.0 0.2 GO:0001865 NK T cell differentiation(GO:0001865)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.2 GO:0031838 haptoglobin-hemoglobin complex(GO:0031838)
0.1 0.4 GO:0038045 large latent transforming growth factor-beta complex(GO:0038045)
0.0 0.4 GO:0097208 alveolar lamellar body(GO:0097208)
0.0 0.2 GO:0044194 cytolytic granule(GO:0044194)
0.0 0.5 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.1 GO:0070442 integrin alphaIIb-beta3 complex(GO:0070442)
0.0 0.7 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.2 GO:0001520 outer dense fiber(GO:0001520)
0.0 0.4 GO:0044216 other organism(GO:0044215) other organism cell(GO:0044216) other organism part(GO:0044217)
0.0 0.1 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.0 0.5 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.5 GO:0046658 anchored component of plasma membrane(GO:0046658)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.2 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.2 1.2 GO:0030492 hemoglobin binding(GO:0030492)
0.2 0.5 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.1 0.4 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.1 0.6 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.1 0.3 GO:0008147 structural constituent of bone(GO:0008147)
0.1 0.3 GO:0051380 norepinephrine binding(GO:0051380)
0.1 0.4 GO:0050436 microfibril binding(GO:0050436)
0.1 0.8 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.1 0.4 GO:0001851 complement component C3b binding(GO:0001851)
0.1 0.4 GO:0001849 complement component C1q binding(GO:0001849)
0.1 0.3 GO:0019958 C-X-C chemokine binding(GO:0019958)
0.0 0.3 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 1.5 GO:0008009 chemokine activity(GO:0008009)
0.0 0.2 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.0 0.2 GO:0004852 uroporphyrinogen-III synthase activity(GO:0004852)
0.0 0.1 GO:0004911 interleukin-2 receptor activity(GO:0004911)
0.0 0.7 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 0.1 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.0 0.1 GO:0008970 phosphatidylcholine 1-acylhydrolase activity(GO:0008970)
0.0 0.4 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.3 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.1 GO:0004908 interleukin-1 receptor activity(GO:0004908)
0.0 0.4 GO:0070001 aspartic-type endopeptidase activity(GO:0004190) aspartic-type peptidase activity(GO:0070001)
0.0 1.0 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.4 GO:0043274 phospholipase binding(GO:0043274)
0.0 0.1 GO:0004952 dopamine neurotransmitter receptor activity(GO:0004952)
0.0 0.2 GO:0004017 adenylate kinase activity(GO:0004017)
0.0 0.7 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.2 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 0.2 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.1 GO:0042610 CD8 receptor binding(GO:0042610)
0.0 0.1 GO:0090554 phosphatidylcholine-translocating ATPase activity(GO:0090554)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 1.2 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 1.3 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.0 0.8 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 1.6 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.0 1.6 PID IL12 2PATHWAY IL12-mediated signaling events
0.0 0.3 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.2 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 0.7 PID ARF6 PATHWAY Arf6 signaling events
0.0 1.4 PID TCR PATHWAY TCR signaling in naïve CD4+ T cells
0.0 0.4 PID CONE PATHWAY Visual signal transduction: Cones

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.1 3.0 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.1 0.8 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.9 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.8 REACTOME ACTIVATED POINT MUTANTS OF FGFR2 Genes involved in Activated point mutants of FGFR2
0.0 0.4 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.6 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.4 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.5 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 0.7 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 0.4 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.5 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.6 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.3 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.3 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.2 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.1 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway