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2D miR_HR1_12

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Results for Tfap2e

Z-value: 0.31

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Transcription factors associated with Tfap2e

Gene Symbol Gene ID Gene Info
ENSMUSG00000042477.7 transcription factor AP-2, epsilon

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Tfap2emm10_v2_chr4_-_126736236_126736245-0.274.0e-01Click!

Activity profile of Tfap2e motif

Sorted Z-values of Tfap2e motif

Promoter Log-likelihood Transcript Gene Gene Info
chr19_-_42752710 0.30 ENSMUST00000076505.3
pyridine nucleotide-disulphide oxidoreductase domain 2
chr17_+_37046555 0.26 ENSMUST00000172789.1
gamma-aminobutyric acid (GABA) B receptor, 1
chr5_-_34187670 0.22 ENSMUST00000042701.6
ENSMUST00000119171.1
Max dimerization protein 4
chr15_-_102524615 0.21 ENSMUST00000023814.7
neuropeptide FF-amide peptide precursor
chr8_+_94152607 0.21 ENSMUST00000034211.8
metallothionein 3
chr4_-_140774196 0.19 ENSMUST00000026381.6
peptidyl arginine deiminase, type IV
chr9_-_121759788 0.18 ENSMUST00000181325.1
RIKEN cDNA E530011L22 gene
chr9_+_109931774 0.17 ENSMUST00000169851.2
microtubule-associated protein 4
chr7_-_45333754 0.17 ENSMUST00000042194.8
transient receptor potential cation channel, subfamily M, member 4
chr3_+_89831352 0.15 ENSMUST00000050401.5
src homology 2 domain-containing transforming protein E
chr14_+_51114455 0.15 ENSMUST00000100645.3
epididymal protein 3B
chr11_-_102897123 0.14 ENSMUST00000067444.3
glial fibrillary acidic protein
chr3_-_153725062 0.13 ENSMUST00000064460.5
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3
chr7_-_30598863 0.13 ENSMUST00000108150.1
zinc finger and BTB domain containing 32
chr5_+_64970069 0.12 ENSMUST00000031080.8
family with sequence similarity 114, member A1
chr1_-_136131171 0.12 ENSMUST00000146091.3
ENSMUST00000165464.1
ENSMUST00000166747.1
ENSMUST00000134998.1
predicted gene 15850
chr15_-_97831460 0.10 ENSMUST00000079838.7
ENSMUST00000118294.1
histone deacetylase 7
chr6_-_82774448 0.10 ENSMUST00000000642.4
hexokinase 2
chr9_+_100643605 0.09 ENSMUST00000041418.6
stromal antigen 1
chr6_-_39725193 0.09 ENSMUST00000101497.3
Braf transforming gene
chr8_+_107293500 0.09 ENSMUST00000151114.1
ENSMUST00000075922.4
ENSMUST00000125721.1
nuclear factor of activated T cells 5
chr15_+_99591028 0.09 ENSMUST00000169082.1
aquaporin 5
chr12_+_109544498 0.09 ENSMUST00000126289.1
maternally expressed 3
chr9_-_21592805 0.09 ENSMUST00000034700.7
ENSMUST00000180365.1
ENSMUST00000078572.7
Yip1 domain family, member 2
chr1_+_86154752 0.08 ENSMUST00000113309.2
ENSMUST00000027434.8
ENSMUST00000131412.1
armadillo repeat containing 9
chr9_+_100643448 0.08 ENSMUST00000146312.1
ENSMUST00000129269.1
stromal antigen 1
chr11_+_50025309 0.08 ENSMUST00000054684.7
ENSMUST00000102776.4
ring finger protein 130
chr7_-_44524642 0.08 ENSMUST00000165208.2
myosin binding protein C, fast-type
chr4_-_108217897 0.07 ENSMUST00000106690.1
ENSMUST00000043793.6
zyg-11 family member A, cell cycle regulator
chr4_+_148039097 0.07 ENSMUST00000141283.1
5,10-methylenetetrahydrofolate reductase
chr10_-_127211528 0.07 ENSMUST00000013970.7
phosphatidylinositol-5-phosphate 4-kinase, type II, gamma
chr8_+_107293463 0.06 ENSMUST00000169453.1
nuclear factor of activated T cells 5
chr7_-_116443439 0.06 ENSMUST00000170430.1
phosphatidylinositol 3-kinase, C2 domain containing, alpha polypeptide
chr15_-_58214882 0.06 ENSMUST00000022986.6
F-box protein 32
chr17_-_63863791 0.06 ENSMUST00000050753.3
RIKEN cDNA A930002H24 gene
chr10_+_121365078 0.06 ENSMUST00000040344.6
glucosamine (N-acetyl)-6-sulfatase
chr14_+_56887795 0.05 ENSMUST00000022511.8
zinc finger, MYM-type 2
chrX_+_73716577 0.05 ENSMUST00000002084.7
ATP-binding cassette, sub-family D (ALD), member 1
chr7_-_19629355 0.05 ENSMUST00000049912.8
ENSMUST00000094762.3
ENSMUST00000098754.4
avian reticuloendotheliosis viral (v-rel) oncogene related B
chr9_+_100643755 0.05 ENSMUST00000133388.1
stromal antigen 1
chrX_+_73716712 0.05 ENSMUST00000114461.2
ATP-binding cassette, sub-family D (ALD), member 1
chr2_-_150904620 0.05 ENSMUST00000056149.8
abhydrolase domain containing 12
chr3_-_113630068 0.05 ENSMUST00000092154.3
ENSMUST00000106536.1
ENSMUST00000106535.1
RNA-binding region (RNP1, RRM) containing 3
chr3_+_103914560 0.05 ENSMUST00000106806.1
rosbin, round spermatid basic protein 1
chrX_-_103981242 0.05 ENSMUST00000121153.1
ENSMUST00000070705.4
ring finger protein, LIM domain interacting
chr9_-_97111117 0.05 ENSMUST00000085206.4
solute carrier family 25, member 36
chr11_+_101260569 0.04 ENSMUST00000103108.1
WNK lysine deficient protein kinase 4
chr11_+_117654798 0.04 ENSMUST00000106344.1
trinucleotide repeat containing 6C
chr13_+_54949388 0.04 ENSMUST00000026994.7
ENSMUST00000109994.2
unc-5 homolog A (C. elegans)
chr9_+_108953597 0.03 ENSMUST00000026740.5
collagen, type VII, alpha 1
chr11_-_102897146 0.03 ENSMUST00000077902.4
glial fibrillary acidic protein
chr9_+_108953578 0.03 ENSMUST00000112070.1
collagen, type VII, alpha 1
chr2_+_149830840 0.03 ENSMUST00000109934.1
ENSMUST00000140870.1
synapse differentiation inducing 1
chr2_-_34754364 0.03 ENSMUST00000142436.1
ENSMUST00000113099.3
ENSMUST00000028224.8
GTPase activating protein and VPS9 domains 1
chr19_-_53944621 0.02 ENSMUST00000135402.2
BBSome interacting protein 1
chr6_+_108213086 0.02 ENSMUST00000032192.6
inositol 1,4,5-trisphosphate receptor 1
chr1_+_136131382 0.02 ENSMUST00000075164.4
kinesin family member 21B
chr11_-_51756378 0.02 ENSMUST00000109092.1
ENSMUST00000064297.4
ENSMUST00000109097.2
Sec24 related gene family, member A (S. cerevisiae)
chr6_-_39725448 0.02 ENSMUST00000002487.8
Braf transforming gene
chr11_+_95414078 0.02 ENSMUST00000107724.2
ENSMUST00000150884.1
ENSMUST00000107722.1
ENSMUST00000127713.1
speckle-type POZ protein
chr7_+_19004047 0.02 ENSMUST00000053713.3
interferon regulatory factor 2 binding protein 1
chr16_+_93832121 0.02 ENSMUST00000044068.6
microrchidia 3
chr7_+_81057589 0.02 ENSMUST00000107348.1
alpha-kinase 3
chr10_+_67535465 0.01 ENSMUST00000145754.1
early growth response 2
chr2_+_149830788 0.01 ENSMUST00000109935.1
synapse differentiation inducing 1
chr5_-_137314175 0.01 ENSMUST00000024119.9
thyroid hormone receptor interactor 6
chr13_-_101768154 0.01 ENSMUST00000055518.6
phosphatidylinositol 3-kinase, regulatory subunit, polypeptide 1 (p85 alpha)
chr16_-_46496772 0.01 ENSMUST00000149901.1
ENSMUST00000096052.2
poliovirus receptor-related 3
chr13_+_30659999 0.01 ENSMUST00000091672.6
ENSMUST00000110310.1
ENSMUST00000095914.5
dual specificity phosphatase 22
chr16_-_46496955 0.01 ENSMUST00000023335.6
ENSMUST00000023334.8
poliovirus receptor-related 3
chr2_+_27165233 0.01 ENSMUST00000000910.6
dopamine beta hydroxylase
chr4_-_127354074 0.01 ENSMUST00000106090.1
ENSMUST00000060419.1
gap junction protein, beta 4
chr12_-_45074112 0.01 ENSMUST00000120531.1
ENSMUST00000143376.1
syntaxin binding protein 6 (amisyn)
chr17_-_35697971 0.01 ENSMUST00000146472.1
discoidin domain receptor family, member 1
chr3_-_84040151 0.00 ENSMUST00000052342.7
RIKEN cDNA D930015E06 gene
chr2_+_109890846 0.00 ENSMUST00000028583.7
lin-7 homolog C (C. elegans)
chr8_+_41239718 0.00 ENSMUST00000045218.7
pericentriolar material 1
chr6_-_137649211 0.00 ENSMUST00000134630.1
ENSMUST00000058210.6
ENSMUST00000111878.1
epidermal growth factor receptor pathway substrate 8
chr19_+_42518759 0.00 ENSMUST00000026188.3
R3H domain and coiled-coil containing 1 like
chr11_-_3371307 0.00 ENSMUST00000101642.3
ENSMUST00000101640.3
LIM motif-containing protein kinase 2
chr2_+_31314303 0.00 ENSMUST00000113532.2
hemicentin 2
chr1_+_135836380 0.00 ENSMUST00000178204.1
troponin T2, cardiac
chrX_+_7722267 0.00 ENSMUST00000125991.1
ENSMUST00000148624.1
WD repeat domain 45

Network of associatons between targets according to the STRING database.

First level regulatory network of Tfap2e

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0097212 lysosomal membrane organization(GO:0097212)
0.1 0.2 GO:0018101 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.1 0.2 GO:0086047 membrane depolarization during Purkinje myocyte cell action potential(GO:0086047)
0.0 0.3 GO:0014053 negative regulation of gamma-aminobutyric acid secretion(GO:0014053)
0.0 0.2 GO:0051012 microtubule sliding(GO:0051012)
0.0 0.1 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.0 0.2 GO:0070253 somatostatin secretion(GO:0070253)
0.0 0.2 GO:0010624 regulation of Schwann cell proliferation(GO:0010624)
0.0 0.1 GO:1901526 negative regulation of mitochondrial membrane permeability(GO:0035795) positive regulation of macromitophagy(GO:1901526) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925)
0.0 0.1 GO:0071579 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092) regulation of zinc ion transport(GO:0071579)
0.0 0.1 GO:0070829 heterochromatin maintenance(GO:0070829)
0.0 0.0 GO:0046462 monoacylglycerol metabolic process(GO:0046462)
0.0 0.1 GO:0014854 response to inactivity(GO:0014854) response to muscle inactivity(GO:0014870) response to muscle inactivity involved in regulation of muscle adaptation(GO:0014877) response to denervation involved in regulation of muscle adaptation(GO:0014894)
0.0 0.1 GO:2000301 negative regulation of synaptic vesicle exocytosis(GO:2000301)
0.0 0.1 GO:0015670 carbon dioxide transport(GO:0015670)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.0 0.2 GO:0097450 astrocyte end-foot(GO:0097450)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.0 0.3 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 0.1 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.0 0.1 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0 0.1 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.0 0.1 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 0.1 GO:0019158 fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0 0.1 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.1 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway