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2D miR_HR1_12

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Results for Hoxd10

Z-value: 0.30

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Transcription factors associated with Hoxd10

Gene Symbol Gene ID Gene Info
ENSMUSG00000050368.3 homeobox D10

Activity profile of Hoxd10 motif

Sorted Z-values of Hoxd10 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr13_-_71963713 0.82 ENSMUST00000077337.8
Iroquois related homeobox 1 (Drosophila)
chr3_+_138277489 0.71 ENSMUST00000004232.9
alcohol dehydrogenase 1 (class I)
chr3_-_75270073 0.46 ENSMUST00000039047.4
serine (or cysteine) peptidase inhibitor, clade I, member 2
chr19_+_37436707 0.42 ENSMUST00000128184.1
hematopoietically expressed homeobox
chr14_+_103513328 0.39 ENSMUST00000095576.3
sciellin
chr5_+_20702129 0.38 ENSMUST00000101556.4
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr8_+_109990430 0.37 ENSMUST00000001720.7
ENSMUST00000143741.1
tyrosine aminotransferase
chr4_+_102254993 0.34 ENSMUST00000106908.2
phosphodiesterase 4B, cAMP specific
chr3_+_115080965 0.30 ENSMUST00000051309.8
olfactomedin 3
chr9_+_104569671 0.27 ENSMUST00000057742.8
copine IV
chr4_+_100478806 0.22 ENSMUST00000133493.2
ENSMUST00000092730.3
ENSMUST00000106979.3
ubiquitin-conjugating enzyme E2U (putative)
chr6_+_97807014 0.18 ENSMUST00000043637.7
microphthalmia-associated transcription factor
chr1_-_45503282 0.18 ENSMUST00000086430.4
collagen, type V, alpha 2
chr7_+_43690418 0.14 ENSMUST00000056329.6
kallikrein related-peptidase 14
chr10_+_116177351 0.14 ENSMUST00000155606.1
ENSMUST00000128399.1
protein tyrosine phosphatase, receptor type, R
chr7_+_30095150 0.14 ENSMUST00000130526.1
ENSMUST00000108200.1
zinc finger protein 260
chr11_-_99244058 0.14 ENSMUST00000103132.3
ENSMUST00000038214.6
keratin 222
chr2_+_106693185 0.11 ENSMUST00000111063.1
metallophosphoesterase domain containing 2
chr13_+_40917626 0.10 ENSMUST00000067778.6
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme
chr10_-_24101951 0.10 ENSMUST00000170267.1
trace amine-associated receptor 8C
chr14_-_93888732 0.10 ENSMUST00000068992.2
protocadherin 9
chr9_-_45828618 0.09 ENSMUST00000117194.1
centrosomal protein 164
chr12_+_76417598 0.09 ENSMUST00000063977.7
protein phosphatase 1, regulatory subunit 36
chr18_-_6490808 0.09 ENSMUST00000028100.6
ENSMUST00000050542.5
enhancer of polycomb homolog 1 (Drosophila)
chr2_+_21367532 0.08 ENSMUST00000055946.7
G protein-coupled receptor 158
chr3_+_55461758 0.08 ENSMUST00000070418.4
doublecortin-like kinase 1
chrX_-_70365052 0.08 ENSMUST00000101509.2
iduronate 2-sulfatase
chr10_+_69534039 0.08 ENSMUST00000182557.1
ankyrin 3, epithelial
chr7_+_51880312 0.07 ENSMUST00000145049.1
growth arrest specific 2
chr16_-_23029012 0.07 ENSMUST00000039338.6
kininogen 2
chr5_-_92328068 0.07 ENSMUST00000113093.3
chemokine (C-X-C motif) ligand 9
chr1_+_150100093 0.06 ENSMUST00000035065.7
prostaglandin-endoperoxide synthase 2
chr3_+_106486009 0.06 ENSMUST00000183271.1
ENSMUST00000061206.3
DENN/MADD domain containing 2D
chr12_+_55089202 0.06 ENSMUST00000021407.10
signal recognition particle 54A
chr16_-_23029080 0.05 ENSMUST00000100046.2
kininogen 2
chr16_-_23029062 0.04 ENSMUST00000115349.2
kininogen 2
chr9_+_27790947 0.04 ENSMUST00000115243.2
opioid binding protein/cell adhesion molecule-like
chr7_-_84679346 0.04 ENSMUST00000069537.2
ENSMUST00000178385.1
zinc finger, AN1-type domain 6
chr10_+_128790903 0.04 ENSMUST00000026411.6
matrix metallopeptidase 19
chr1_-_149922339 0.04 ENSMUST00000111926.2
phospholipase A2, group IVA (cytosolic, calcium-dependent)
chr15_-_93336800 0.03 ENSMUST00000080299.6
YY1 associated factor 2
chr3_-_95282076 0.03 ENSMUST00000015855.7
prune homolog (Drosophila)
chrX_-_9469288 0.03 ENSMUST00000015484.3
cytochrome b-245, beta polypeptide
chr17_-_46327949 0.02 ENSMUST00000047970.7
ATP-binding cassette, sub-family C (CFTR/MRP), member 10
chr16_+_25801907 0.02 ENSMUST00000040231.6
ENSMUST00000115306.1
ENSMUST00000115304.1
ENSMUST00000115305.1
transformation related protein 63
chr4_-_36136463 0.02 ENSMUST00000098151.2
leucine rich repeat and Ig domain containing 2
chrX_+_14211148 0.02 ENSMUST00000079952.2
predicted gene 5382
chr17_-_37263749 0.02 ENSMUST00000080759.4
olfactory receptor 98
chr4_-_108833608 0.02 ENSMUST00000102742.4
basic transcription factor 3-like 4
chr1_-_132390301 0.02 ENSMUST00000132435.1
transmembrane and coiled-coil domains 2
chr1_-_152625212 0.01 ENSMUST00000027760.7
ral guanine nucleotide dissociation stimulator,-like 1
chrX_+_66653003 0.01 ENSMUST00000036043.4
SLIT and NTRK-like family, member 2
chr15_-_5108469 0.01 ENSMUST00000141020.1
caspase recruitment domain family, member 6
chr4_-_108833544 0.01 ENSMUST00000102740.1
ENSMUST00000102741.1
basic transcription factor 3-like 4
chr2_-_119208767 0.01 ENSMUST00000038439.3
DnaJ (Hsp40) homolog, subfamily C, member 17
chrX_+_7762652 0.01 ENSMUST00000077680.3
ENSMUST00000079542.6
ENSMUST00000115679.1
ENSMUST00000137467.1
transcription factor E3
chr17_-_78684262 0.00 ENSMUST00000145480.1
striatin, calmodulin binding protein
chr11_-_58552237 0.00 ENSMUST00000073933.1
olfactory receptor 328

Network of associatons between targets according to the STRING database.

First level regulatory network of Hoxd10

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0072272 proximal/distal pattern formation involved in metanephric nephron development(GO:0072272)
0.2 0.7 GO:0006069 ethanol oxidation(GO:0006069)
0.1 0.4 GO:0061010 gall bladder development(GO:0061010)
0.1 0.4 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.2 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.0 0.4 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.0 0.3 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 0.1 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.0 0.1 GO:0031394 positive regulation of prostaglandin biosynthetic process(GO:0031394) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.0 0.1 GO:0036438 maintenance of lens transparency(GO:0036438)
0.0 0.1 GO:0007320 insemination(GO:0007320)
0.0 0.2 GO:0044336 canonical Wnt signaling pathway involved in negative regulation of apoptotic process(GO:0044336)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.2 GO:0033503 HULC complex(GO:0033503)
0.0 0.4 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.1 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.3 GO:0000930 gamma-tubulin complex(GO:0000930)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.1 0.4 GO:0070546 L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.1 0.4 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 0.4 GO:0008301 DNA binding, bending(GO:0008301)
0.0 0.1 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.0 0.1 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.0 0.1 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.1 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions