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2D miR_HR1_12

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Results for Hnf1b

Z-value: 1.23

Motif logo

Transcription factors associated with Hnf1b

Gene Symbol Gene ID Gene Info
ENSMUSG00000020679.5 HNF1 homeobox B

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Hnf1bmm10_v2_chr11_+_83852135_83852242-0.352.7e-01Click!

Activity profile of Hnf1b motif

Sorted Z-values of Hnf1b motif

Promoter Log-likelihood Transcript Gene Gene Info
chr1_-_158814469 5.09 ENSMUST00000161589.2
pappalysin 2
chr7_+_30493622 2.04 ENSMUST00000058280.6
ENSMUST00000133318.1
ENSMUST00000142575.1
ENSMUST00000131040.1
proline dehydrogenase (oxidase) 2
chr5_+_90518932 1.77 ENSMUST00000113179.2
ENSMUST00000128740.1
afamin
chr16_-_45492962 1.72 ENSMUST00000114585.2
predicted gene 609
chr3_+_115080965 1.56 ENSMUST00000051309.8
olfactomedin 3
chrX_+_52791179 1.49 ENSMUST00000101588.1
coiled-coil domain containing 160
chrX_+_164140447 1.49 ENSMUST00000073973.4
angiotensin I converting enzyme (peptidyl-dipeptidase A) 2
chr6_-_52183828 1.46 ENSMUST00000134831.1
homeobox A3
chr13_-_53286052 1.45 ENSMUST00000021918.8
receptor tyrosine kinase-like orphan receptor 2
chr13_+_89540636 1.43 ENSMUST00000022108.7
hyaluronan and proteoglycan link protein 1
chr3_-_72967854 1.39 ENSMUST00000167334.1
sucrase isomaltase (alpha-glucosidase)
chr7_-_101870711 1.39 ENSMUST00000151706.1
folate receptor 1 (adult)
chr2_-_62412219 1.37 ENSMUST00000047812.7
dipeptidylpeptidase 4
chr6_-_147243794 1.37 ENSMUST00000153786.1
predicted gene 15767
chr1_-_20617992 1.32 ENSMUST00000088448.5
polycystic kidney and hepatic disease 1
chr17_+_23660477 1.22 ENSMUST00000062967.8
coiled-coil domain containing 64B
chr12_+_58211772 1.20 ENSMUST00000110671.2
ENSMUST00000044299.2
somatostatin receptor 1
chr1_+_88211956 1.17 ENSMUST00000073049.6
UDP glucuronosyltransferase 1 family, polypeptide A1
chr4_-_53262547 1.15 ENSMUST00000098075.2
expressed sequence AI427809
chr2_-_35100677 1.14 ENSMUST00000045776.4
ENSMUST00000113050.3
expressed sequence AI182371
chr5_+_102845007 1.12 ENSMUST00000070000.4
Rho GTPase activating protein 24
chr18_+_33464163 1.08 ENSMUST00000097634.3
predicted gene 10549
chr16_+_96361654 1.08 ENSMUST00000113794.1
immunoglobulin superfamily, member 5
chr9_+_72958785 1.08 ENSMUST00000098567.2
ENSMUST00000034734.8
dyslexia susceptibility 1 candidate 1 homolog (human)
chr1_+_88138364 1.06 ENSMUST00000014263.4
UDP glucuronosyltransferase 1 family, polypeptide A6A
chr1_+_125676969 1.03 ENSMUST00000027581.6
G protein-coupled receptor 39
chr1_+_88070765 1.01 ENSMUST00000073772.4
UDP glucuronosyltransferase 1 family, polypeptide A9
chrX_+_140907602 0.98 ENSMUST00000033806.4
V-set and immunoglobulin domain containing 1
chr4_-_140617062 0.96 ENSMUST00000154979.1
Rho guanine nucleotide exchange factor (GEF) 10-like
chr12_+_59095653 0.94 ENSMUST00000021384.4
melanoma inhibitory activity 2
chr5_-_87569023 0.94 ENSMUST00000113314.2
sulfotransferase family 1D, member 1
chr1_+_88166004 0.93 ENSMUST00000097659.4
UDP glucuronosyltransferase 1 family, polypeptide A5
chr16_+_96361749 0.92 ENSMUST00000000163.6
ENSMUST00000081093.3
ENSMUST00000113795.1
immunoglobulin superfamily, member 5
chrX_-_139085230 0.90 ENSMUST00000152457.1
serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
chr15_+_10215955 0.89 ENSMUST00000130720.1
prolactin receptor
chr8_-_107065632 0.89 ENSMUST00000034393.5
transmembrane emp24 protein transport domain containing 6
chr11_+_78037959 0.89 ENSMUST00000073660.6
flotillin 2
chr5_-_87535113 0.88 ENSMUST00000120150.1
sulfotransferase family 1B, member 1
chr11_+_78037931 0.86 ENSMUST00000072289.5
ENSMUST00000100784.2
flotillin 2
chr3_-_116712696 0.86 ENSMUST00000169530.1
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member 3
chr19_+_42045792 0.86 ENSMUST00000172244.1
ENSMUST00000081714.4
4-hydroxy-2-oxoglutarate aldolase 1
chr6_-_137571007 0.84 ENSMUST00000100841.2
epidermal growth factor receptor pathway substrate 8
chr9_+_21835506 0.83 ENSMUST00000058777.6
predicted gene 6484
chr19_+_43782181 0.83 ENSMUST00000026208.4
ATP-binding cassette, sub-family C (CFTR/MRP), member 2
chr19_-_46672883 0.82 ENSMUST00000026012.7
cytochrome P450, family 17, subfamily a, polypeptide 1
chr11_+_101367542 0.82 ENSMUST00000019469.2
glucose-6-phosphatase, catalytic
chr1_+_88055377 0.82 ENSMUST00000138182.1
ENSMUST00000113142.3
UDP glycosyltransferase 1 family, polypeptide A10
chrX_-_139085211 0.80 ENSMUST00000033626.8
ENSMUST00000060824.3
serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7
chrX_+_101376359 0.79 ENSMUST00000119080.1
gap junction protein, beta 1
chr10_-_30842765 0.78 ENSMUST00000019924.8
hairy/enhancer-of-split related with YRPW motif 2
chr11_+_3983636 0.77 ENSMUST00000078757.1
galactose-3-O-sulfotransferase 1
chr11_+_78465697 0.77 ENSMUST00000001126.3
solute carrier family 46, member 1
chr5_+_150952607 0.74 ENSMUST00000078856.6
klotho
chr13_-_23914998 0.74 ENSMUST00000021769.8
ENSMUST00000110407.2
solute carrier family 17 (sodium phosphate), member 4
chr11_+_3983704 0.71 ENSMUST00000063004.7
galactose-3-O-sulfotransferase 1
chr6_-_24168083 0.71 ENSMUST00000031713.8
solute carrier family 13 (sodium/sulfate symporters), member 1
chr12_+_76533540 0.64 ENSMUST00000075249.4
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr3_-_113291449 0.64 ENSMUST00000179568.1
amylase 2a4
chr8_-_93535707 0.63 ENSMUST00000077816.6
carboxylesterase 5A
chr6_-_116716888 0.63 ENSMUST00000056623.6
transmembrane protein 72
chr5_+_107497718 0.62 ENSMUST00000112671.2
RIKEN cDNA A830010M20 gene
chr19_+_56287911 0.61 ENSMUST00000095948.4
hyaluronic acid binding protein 2
chr14_+_118787894 0.60 ENSMUST00000047761.6
ENSMUST00000071546.7
claudin 10
chr5_-_87337165 0.60 ENSMUST00000031195.2
UDP glucuronosyltransferase 2 family, polypeptide A3
chr7_+_90348699 0.59 ENSMUST00000107211.1
ENSMUST00000107210.1
synaptotagmin-like 2
chr4_+_138967112 0.58 ENSMUST00000116094.2
ring finger protein 186
chr13_-_21453714 0.58 ENSMUST00000032820.7
ENSMUST00000110485.1
zinc finger and SCAN domain containing 26
chr12_-_12940600 0.58 ENSMUST00000130990.1
v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)
chr16_+_24448082 0.57 ENSMUST00000078988.2
LIM domain containing preferred translocation partner in lipoma
chr11_+_7197780 0.55 ENSMUST00000020704.7
insulin-like growth factor binding protein 1
chr1_+_88055467 0.54 ENSMUST00000173325.1
UDP glycosyltransferase 1 family, polypeptide A10
chr17_+_57062231 0.53 ENSMUST00000097299.3
ENSMUST00000169543.1
ENSMUST00000163763.1
crumbs homolog 3 (Drosophila)
chr17_+_57062486 0.53 ENSMUST00000163628.1
crumbs homolog 3 (Drosophila)
chr4_-_139968026 0.52 ENSMUST00000105031.2
kelch domain containing 7A
chr18_-_43737186 0.51 ENSMUST00000025381.2
serine peptidase inhibitor, Kazal type 3
chr4_+_11758147 0.51 ENSMUST00000029871.5
ENSMUST00000108303.1
cadherin 17
chr9_-_77045788 0.49 ENSMUST00000034911.6
tubulointerstitial nephritis antigen
chr10_-_10472314 0.49 ENSMUST00000179956.1
ENSMUST00000172530.1
ENSMUST00000132573.1
androglobin
chr11_+_44518959 0.49 ENSMUST00000019333.3
ring finger protein 145
chr7_+_131032061 0.49 ENSMUST00000084509.3
deleted in malignant brain tumors 1
chr13_+_54701457 0.48 ENSMUST00000037145.7
cadherin-related family member 2
chr4_+_150853919 0.48 ENSMUST00000073600.2
ERBB receptor feedback inhibitor 1
chr4_-_111898695 0.47 ENSMUST00000102720.1
solute carrier family 5 (sodium/glucose cotransporter), member 9
chr14_+_26894557 0.46 ENSMUST00000090337.4
ENSMUST00000165929.2
ankyrin repeat and SOCS box-containing 14
chr13_+_4191163 0.45 ENSMUST00000021634.2
aldo-keto reductase family 1, member C13
chr9_+_54538984 0.45 ENSMUST00000060242.5
ENSMUST00000118413.1
SH2 domain containing 7
chr11_-_6230127 0.45 ENSMUST00000004505.2
NPC1-like 1
chr13_+_55152640 0.44 ENSMUST00000005452.5
fibroblast growth factor receptor 4
chr6_+_38918969 0.43 ENSMUST00000003017.6
thromboxane A synthase 1, platelet
chr19_-_57197556 0.42 ENSMUST00000099294.2
actin-binding LIM protein 1
chr7_-_119895446 0.42 ENSMUST00000098080.2
DCN1, defective in cullin neddylation 1, domain containing 3 (S. cerevisiae)
chr5_+_90490714 0.41 ENSMUST00000042755.3
alpha fetoprotein
chr15_+_99393574 0.41 ENSMUST00000162624.1
transmembrane BAX inhibitor motif containing 6
chr1_+_40439627 0.41 ENSMUST00000097772.3
interleukin 1 receptor-like 1
chr11_+_115834314 0.40 ENSMUST00000173289.1
ENSMUST00000137900.1
lethal giant larvae homolog 2 (Drosophila)
chr8_+_70724064 0.40 ENSMUST00000034307.7
ENSMUST00000110095.2
phosphodiesterase 4C, cAMP specific
chr19_-_39740999 0.40 ENSMUST00000099472.3
cytochrome P450, family 2, subfamily c, polypeptide 68
chr10_-_89533550 0.40 ENSMUST00000105297.1
nuclear receptor subfamily 1, group H, member 4
chr7_-_45062393 0.40 ENSMUST00000129101.1
proline-rich Gla (G-carboxyglutamic acid) polypeptide 2
chr3_+_90537306 0.39 ENSMUST00000107335.1
S100 calcium binding protein A16
chr11_+_85832551 0.38 ENSMUST00000000095.6
T-box 2
chr11_-_75937726 0.38 ENSMUST00000121287.1
rabphilin 3A-like (without C2 domains)
chr1_+_130731963 0.37 ENSMUST00000039323.6
expressed sequence AA986860
chr8_-_122476036 0.37 ENSMUST00000014614.3
ring finger protein 166
chr11_-_76027726 0.37 ENSMUST00000021207.6
family with sequence similarity 101, member B
chr5_-_108675569 0.37 ENSMUST00000051757.7
solute carrier family 26 (sulfate transporter), member 1
chrX_+_107792583 0.36 ENSMUST00000101292.2
family with sequence similarity 46, member D
chr15_+_99393610 0.36 ENSMUST00000159531.1
transmembrane BAX inhibitor motif containing 6
chr16_-_79091078 0.36 ENSMUST00000023566.4
ENSMUST00000060402.5
transmembrane protease, serine 15
chr6_-_129100903 0.36 ENSMUST00000032258.6
C-type lectin domain family 2, member e
chr19_+_60889749 0.35 ENSMUST00000003313.8
G protein-coupled receptor kinase 5
chr3_-_144819494 0.35 ENSMUST00000029929.7
chloride channel calcium activated 2
chr7_-_144751968 0.35 ENSMUST00000155175.1
anoctamin 1, calcium activated chloride channel
chr11_+_110968016 0.34 ENSMUST00000106636.1
ENSMUST00000180023.1
potassium inwardly-rectifying channel, subfamily J, member 16
chr5_-_114444036 0.34 ENSMUST00000031560.7
methylmalonic aciduria (cobalamin deficiency) type B homolog (human)
chr4_+_19280850 0.32 ENSMUST00000102999.1
cyclic nucleotide gated channel beta 3
chr7_-_119479249 0.32 ENSMUST00000033263.4
uromodulin
chrX_+_101449078 0.32 ENSMUST00000033674.5
integrin beta 1 binding protein 2
chr2_+_91265252 0.31 ENSMUST00000028691.6
ADP-ribosylation factor GTPase activating protein 2
chr1_+_181051232 0.31 ENSMUST00000036819.6
RIKEN cDNA 9130409I23 gene
chr5_-_106926245 0.31 ENSMUST00000117588.1
HFM1, ATP-dependent DNA helicase homolog (S. cerevisiae)
chr16_+_33251415 0.31 ENSMUST00000023502.4
sorting nexin 4
chr7_+_141746736 0.30 ENSMUST00000026590.8
mucin 2
chrX_+_164090187 0.30 ENSMUST00000015545.3
transmembrane protein 27
chr6_-_129876659 0.29 ENSMUST00000014687.4
ENSMUST00000122219.1
killer cell lectin-like receptor, subfamily A, member 17
chr19_+_56287943 0.28 ENSMUST00000166049.1
hyaluronic acid binding protein 2
chr4_-_99654983 0.28 ENSMUST00000136525.1
predicted gene 12688
chr1_+_58795371 0.28 ENSMUST00000027189.8
caspase 8
chr3_+_90537242 0.28 ENSMUST00000098911.3
S100 calcium binding protein A16
chr15_-_36879816 0.27 ENSMUST00000100713.2
predicted gene 10384
chr5_+_107497762 0.27 ENSMUST00000152474.1
ENSMUST00000060553.7
RIKEN cDNA A830010M20 gene
chr19_-_11856001 0.26 ENSMUST00000079875.3
olfactory receptor 1418
chr5_-_100373484 0.25 ENSMUST00000182433.1
Sec31 homolog A (S. cerevisiae)
chr1_-_187215421 0.24 ENSMUST00000110945.3
ENSMUST00000183931.1
ENSMUST00000027908.6
spermatogenesis associated 17
chr19_+_5878622 0.24 ENSMUST00000136833.1
ENSMUST00000141362.1
solute carrier family 25, member 45
chr6_-_38124568 0.24 ENSMUST00000040259.4
ATPase, H+ transporting, lysosomal V0 subunit A4
chr4_-_134767940 0.23 ENSMUST00000037828.6
low density lipoprotein receptor adaptor protein 1
chr7_-_28962265 0.23 ENSMUST00000068045.7
actinin alpha 4
chr6_+_134920401 0.23 ENSMUST00000067327.4
ENSMUST00000003115.6
cyclin-dependent kinase inhibitor 1B
chr11_+_83852135 0.23 ENSMUST00000146786.1
HNF1 homeobox B
chr4_+_44943727 0.22 ENSMUST00000154177.1
predicted gene 12678
chr17_+_74395607 0.22 ENSMUST00000179074.1
ENSMUST00000024870.6
solute carrier family 30 (zinc transporter), member 6
chr2_+_70039114 0.22 ENSMUST00000060208.4
myosin IIIB
chr3_+_69222412 0.22 ENSMUST00000183126.1
ADP-ribosylation factor-like 14
chr9_+_54980880 0.22 ENSMUST00000093844.3
cholinergic receptor, nicotinic, alpha polypeptide 5
chr7_+_45062429 0.21 ENSMUST00000107830.1
ENSMUST00000003513.3
ENSMUST00000107829.1
ENSMUST00000150609.1
nitric oxide synthase interacting protein
chr1_+_133309778 0.21 ENSMUST00000094557.4
ENSMUST00000183457.1
ENSMUST00000183738.1
ENSMUST00000185157.1
ENSMUST00000184603.1
golgi transport 1 homolog A (S. cerevisiae)
KiSS-1 metastasis-suppressor
KISS1 isoform e
chr8_-_67974567 0.20 ENSMUST00000098696.3
ENSMUST00000038959.9
ENSMUST00000093469.4
pleckstrin and Sec7 domain containing 3
chr5_+_90460889 0.20 ENSMUST00000031314.8
albumin
chr12_-_103631404 0.20 ENSMUST00000121625.1
ENSMUST00000044231.5
serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 10
chr19_+_39113898 0.19 ENSMUST00000087234.2
cytochrome P450, family 2, subfamily c, polypeptide 66
chr4_-_108144986 0.19 ENSMUST00000130776.1
sterol carrier protein 2, liver
chr5_-_38491948 0.19 ENSMUST00000129099.1
solute carrier family 2 (facilitated glucose transporter), member 9
chr6_-_129622685 0.18 ENSMUST00000032252.5
killer cell lectin-like receptor subfamily K, member 1
chr14_+_61309753 0.18 ENSMUST00000055159.7
ADP-ribosylation factor-like 11
chr17_-_33718591 0.17 ENSMUST00000174040.1
ENSMUST00000173015.1
ENSMUST00000066121.6
ENSMUST00000172767.1
ENSMUST00000173329.1
membrane-associated ring finger (C3HC4) 2
chr18_-_66022580 0.17 ENSMUST00000143990.1
lectin, mannose-binding, 1
chr13_-_73678005 0.17 ENSMUST00000022105.7
ENSMUST00000109680.2
ENSMUST00000109679.2
solute carrier family 6 (neurotransmitter transporter), member 18
chr11_-_75937677 0.16 ENSMUST00000108420.2
rabphilin 3A-like (without C2 domains)
chr7_-_6011010 0.16 ENSMUST00000086338.1
vomeronasal 1 receptor 65
chr10_-_89621253 0.16 ENSMUST00000020102.7
solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 8
chrX_+_68761839 0.16 ENSMUST00000069731.5
fragile X mental retardation 1 neighbor
chr12_+_4769375 0.15 ENSMUST00000178879.1
profilin family, member 4
chr17_+_47737030 0.15 ENSMUST00000086932.3
transcription factor EB
chr10_+_102159000 0.15 ENSMUST00000020039.6
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr3_-_116712644 0.15 ENSMUST00000029569.2
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member 3
chr4_+_48279794 0.15 ENSMUST00000030029.3
inversin
chr4_+_99030946 0.15 ENSMUST00000030280.6
angiopoietin-like 3
chr9_-_44767792 0.14 ENSMUST00000034607.9
archain 1
chr1_-_36273425 0.14 ENSMUST00000056946.6
neuralized homolog 3 homolog (Drosophila)
chr13_+_23782572 0.14 ENSMUST00000074067.2
tripartite motif-containing 38
chr4_-_103026709 0.13 ENSMUST00000084382.5
ENSMUST00000106869.2
insulin-like 5
chr7_+_24897381 0.13 ENSMUST00000003469.7
CD79A antigen (immunoglobulin-associated alpha)
chr9_+_67840386 0.13 ENSMUST00000077879.5
vacuolar protein sorting 13C (yeast)
chr3_-_83049797 0.13 ENSMUST00000048246.3
fibrinogen beta chain
chr14_+_46882854 0.12 ENSMUST00000022386.8
ENSMUST00000100672.3
sterile alpha motif domain containing 4
chr7_-_29505447 0.12 ENSMUST00000183096.1
ENSMUST00000085809.4
signal-induced proliferation-associated 1 like 3
chr7_-_28962223 0.12 ENSMUST00000127210.1
actinin alpha 4
chr14_+_34085978 0.12 ENSMUST00000022519.8
annexin A8
chr5_+_65348386 0.11 ENSMUST00000031096.7
klotho beta
chr14_+_48446340 0.11 ENSMUST00000111735.2
transmembrane protein 260
chr7_+_27731398 0.10 ENSMUST00000130997.1
zinc finger protein 60
chr10_-_107719978 0.10 ENSMUST00000050702.7
protein tyrosine phosphatase, receptor type, Q
chr14_+_34086008 0.10 ENSMUST00000120077.1
annexin A8
chr11_-_84167466 0.09 ENSMUST00000050771.7
predicted gene 11437
chr1_+_172126750 0.09 ENSMUST00000075895.2
ENSMUST00000111252.3
peroxisomal biogenesis factor 19
chr18_+_35599219 0.09 ENSMUST00000115734.1
polyadenylate-binding protein-interacting protein 2
chr1_+_133246092 0.08 ENSMUST00000038295.8
ENSMUST00000105082.2
pleckstrin homology domain containing, family A member 6
chr9_+_77046680 0.08 ENSMUST00000184488.1
RP23-282G22.2
chr19_+_27217011 0.08 ENSMUST00000164746.1
ENSMUST00000172302.1
very low density lipoprotein receptor
chr14_+_79515618 0.08 ENSMUST00000110835.1
E74-like factor 1
chr3_-_69859875 0.07 ENSMUST00000051239.7
ENSMUST00000171529.1
serine palmitoyltransferase, small subunit B
chr9_-_71163224 0.07 ENSMUST00000074465.2
aquaporin 9
chr2_+_162987502 0.07 ENSMUST00000117123.1
serum/glucocorticoid regulated kinase 2
chr8_+_68276567 0.07 ENSMUST00000066594.3
SH2 domain containing 4A
chr6_+_52177498 0.07 ENSMUST00000070587.3
RIKEN cDNA 5730596B20 gene
chr7_+_141215852 0.06 ENSMUST00000046890.5
ENSMUST00000133763.1
Ras association (RalGDS/AF-6) domain family (N-terminal) member 7
chr10_+_128411616 0.06 ENSMUST00000096386.5
ENSMUST00000171342.1
ring finger protein 41
chr11_+_115912001 0.06 ENSMUST00000132961.1
small integral membrane protein 6
chr1_-_187215454 0.06 ENSMUST00000183819.1
spermatogenesis associated 17

Network of associatons between targets according to the STRING database.

First level regulatory network of Hnf1b

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.0 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.6 1.7 GO:1903903 regulation of establishment of T cell polarity(GO:1903903)
0.6 1.7 GO:0033189 response to vitamin A(GO:0033189)
0.5 5.5 GO:0052697 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.5 1.4 GO:0010716 negative regulation of extracellular matrix disassembly(GO:0010716)
0.4 1.5 GO:0015827 aromatic amino acid transport(GO:0015801) tryptophan transport(GO:0015827)
0.3 1.0 GO:0035483 gastric emptying(GO:0035483)
0.3 0.6 GO:0052695 cellular glucuronidation(GO:0052695)
0.3 0.9 GO:0009812 flavonoid metabolic process(GO:0009812)
0.3 1.5 GO:0007223 Wnt signaling pathway, calcium modulating pathway(GO:0007223)
0.3 0.9 GO:0009436 glyoxylate catabolic process(GO:0009436)
0.2 1.5 GO:0021615 specification of organ position(GO:0010159) glossopharyngeal nerve morphogenesis(GO:0021615)
0.2 0.8 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.2 1.0 GO:0015788 UDP-N-acetylglucosamine transport(GO:0015788)
0.2 0.8 GO:0035905 ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910) negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000820)
0.2 0.8 GO:0015886 heme transport(GO:0015886)
0.2 0.9 GO:0000103 sulfate assimilation(GO:0000103)
0.2 0.5 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.2 1.5 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.2 1.3 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.2 0.8 GO:0031438 regulation of mRNA cleavage(GO:0031437) negative regulation of mRNA cleavage(GO:0031438) regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904720) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721)
0.2 1.4 GO:0071231 neural crest cell migration involved in heart formation(GO:0003147) anterior neural tube closure(GO:0061713) cellular response to folic acid(GO:0071231)
0.1 0.9 GO:0038161 prolactin signaling pathway(GO:0038161)
0.1 0.4 GO:0061144 alveolar secondary septum development(GO:0061144)
0.1 0.8 GO:0015760 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.1 0.4 GO:0034971 histone H3-R17 methylation(GO:0034971)
0.1 0.4 GO:0060596 muscle cell fate determination(GO:0007521) mammary placode formation(GO:0060596)
0.1 1.1 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.1 0.9 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.1 0.2 GO:0090118 receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport(GO:0090118)
0.1 1.1 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.1 0.4 GO:1902396 protein localization to bicellular tight junction(GO:1902396)
0.1 0.3 GO:0072236 metanephric loop of Henle development(GO:0072236)
0.1 0.4 GO:0016332 establishment or maintenance of polarity of embryonic epithelium(GO:0016332)
0.1 0.5 GO:0042536 negative regulation of tumor necrosis factor biosynthetic process(GO:0042536)
0.1 0.4 GO:0007217 tachykinin receptor signaling pathway(GO:0007217)
0.1 1.4 GO:0042448 progesterone metabolic process(GO:0042448)
0.1 0.1 GO:0060971 embryonic heart tube left/right pattern formation(GO:0060971)
0.1 0.6 GO:0045631 regulation of auditory receptor cell differentiation(GO:0045607) regulation of mechanoreceptor differentiation(GO:0045631) regulation of inner ear receptor cell differentiation(GO:2000980)
0.1 1.2 GO:0030277 maintenance of gastrointestinal epithelium(GO:0030277)
0.1 0.8 GO:0015868 purine ribonucleotide transport(GO:0015868)
0.1 1.1 GO:0036158 outer dynein arm assembly(GO:0036158) inner dynein arm assembly(GO:0036159)
0.1 0.5 GO:0060242 contact inhibition(GO:0060242)
0.1 0.2 GO:0051659 maintenance of mitochondrion location(GO:0051659)
0.1 0.4 GO:0019532 oxalate transport(GO:0019532)
0.1 0.2 GO:0002223 stimulatory C-type lectin receptor signaling pathway(GO:0002223)
0.1 0.7 GO:0008272 sulfate transport(GO:0008272)
0.1 0.4 GO:0002826 negative regulation of T-helper 1 type immune response(GO:0002826)
0.1 0.2 GO:1901146 regulation of pronephros size(GO:0035565) mesonephros morphogenesis(GO:0061206) mesonephric nephron development(GO:0061215) mesonephric nephron morphogenesis(GO:0061228) mesenchymal stem cell maintenance involved in mesonephric nephron morphogenesis(GO:0061235) regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:0061295) negative regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:0061296) mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:1901146)
0.1 0.2 GO:0032278 positive regulation of gonadotropin secretion(GO:0032278)
0.1 0.4 GO:0009235 cobalamin metabolic process(GO:0009235)
0.0 0.6 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.0 0.1 GO:0021691 cerebellar Purkinje cell layer maturation(GO:0021691)
0.0 0.3 GO:0002349 histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553)
0.0 0.3 GO:0015705 iodide transport(GO:0015705)
0.0 5.1 GO:0060349 bone morphogenesis(GO:0060349)
0.0 1.0 GO:0032933 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.0 0.6 GO:0070257 positive regulation of mucus secretion(GO:0070257)
0.0 0.2 GO:1902477 defense response to bacterium, incompatible interaction(GO:0009816) regulation of defense response to bacterium, incompatible interaction(GO:1902477)
0.0 0.4 GO:0030299 intestinal cholesterol absorption(GO:0030299)
0.0 0.3 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.0 0.2 GO:1904706 negative regulation of vascular smooth muscle cell proliferation(GO:1904706)
0.0 0.1 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.0 1.3 GO:0010824 regulation of centrosome duplication(GO:0010824)
0.0 0.1 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.0 0.4 GO:0010225 response to UV-C(GO:0010225)
0.0 0.2 GO:1901525 negative regulation of macromitophagy(GO:1901525)
0.0 0.5 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 1.7 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 0.1 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.0 1.2 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.0 0.5 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.0 0.3 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.0 0.2 GO:0070072 vacuolar proton-transporting V-type ATPase complex assembly(GO:0070072)
0.0 0.2 GO:0061088 sequestering of zinc ion(GO:0032119) regulation of sequestering of zinc ion(GO:0061088)
0.0 1.2 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 0.2 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.0 GO:0034442 regulation of lipoprotein oxidation(GO:0034442) negative regulation of lipoprotein oxidation(GO:0034443)
0.0 0.3 GO:0045651 positive regulation of macrophage differentiation(GO:0045651)
0.0 0.2 GO:0035095 behavioral response to nicotine(GO:0035095)
0.0 0.1 GO:0015851 nucleobase transport(GO:0015851) pyrimidine nucleobase transport(GO:0015855)
0.0 0.2 GO:0042989 sequestering of actin monomers(GO:0042989)
0.0 0.1 GO:0034436 glycoprotein transport(GO:0034436)
0.0 0.1 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
0.0 0.1 GO:0016557 peroxisome membrane biogenesis(GO:0016557)
0.0 0.1 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.0 0.2 GO:0051001 negative regulation of nitric-oxide synthase activity(GO:0051001)
0.0 0.4 GO:0006198 cAMP catabolic process(GO:0006198)
0.0 0.0 GO:0044830 modulation by host of viral RNA genome replication(GO:0044830)
0.0 0.2 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.4 GO:0071438 invadopodium membrane(GO:0071438)
0.1 1.7 GO:0001931 uropod(GO:0001931) flotillin complex(GO:0016600) cell trailing edge(GO:0031254)
0.1 0.3 GO:0030690 Noc1p-Noc2p complex(GO:0030690)
0.1 1.2 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 0.5 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.1 0.8 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 1.4 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.1 0.2 GO:0030121 AP-1 adaptor complex(GO:0030121)
0.1 0.8 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.1 GO:0097543 ciliary inversin compartment(GO:0097543)
0.0 0.5 GO:0089717 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.0 0.8 GO:0005922 connexon complex(GO:0005922)
0.0 0.2 GO:0097450 astrocyte end-foot(GO:0097450)
0.0 1.2 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 0.8 GO:0016580 Sin3 complex(GO:0016580)
0.0 1.6 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.2 GO:0000220 vacuolar proton-transporting V-type ATPase, V0 domain(GO:0000220)
0.0 3.7 GO:0005923 bicellular tight junction(GO:0005923)
0.0 0.4 GO:0031143 pseudopodium(GO:0031143)
0.0 0.1 GO:0019815 B cell receptor complex(GO:0019815)
0.0 0.6 GO:0042470 melanosome(GO:0042470) pigment granule(GO:0048770)
0.0 0.1 GO:0061689 tricellular tight junction(GO:0061689)
0.0 0.1 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.2 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.0 0.2 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.2 GO:0032433 filopodium tip(GO:0032433)
0.0 1.2 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 1.0 GO:0031526 brush border membrane(GO:0031526)
0.0 0.1 GO:0031211 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.1 GO:0030126 COPI vesicle coat(GO:0030126)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.8 GO:0008431 vitamin E binding(GO:0008431)
0.4 1.5 GO:0001733 galactosylceramide sulfotransferase activity(GO:0001733)
0.4 1.8 GO:0004062 aryl sulfotransferase activity(GO:0004062)
0.3 1.4 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.3 1.2 GO:0004566 beta-glucuronidase activity(GO:0004566)
0.3 0.8 GO:0050309 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.3 0.8 GO:0035939 microsatellite binding(GO:0035939)
0.3 1.8 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.2 1.2 GO:0004994 somatostatin receptor activity(GO:0004994)
0.2 0.9 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.2 0.8 GO:0015232 heme transporter activity(GO:0015232)
0.2 0.9 GO:0004925 prolactin receptor activity(GO:0004925)
0.2 5.8 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.2 0.5 GO:0035673 oligopeptide transmembrane transporter activity(GO:0035673)
0.1 0.8 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.1 1.4 GO:0051870 methotrexate binding(GO:0051870)
0.1 1.4 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.1 0.6 GO:0004556 alpha-amylase activity(GO:0004556)
0.1 0.4 GO:0004703 G-protein coupled receptor kinase activity(GO:0004703)
0.1 0.4 GO:0038181 bile acid receptor activity(GO:0038181)
0.1 0.3 GO:0042284 sphingolipid delta-4 desaturase activity(GO:0042284)
0.1 0.3 GO:1990460 leptin receptor binding(GO:1990460)
0.1 0.8 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.1 2.0 GO:0071949 FAD binding(GO:0071949)
0.1 1.1 GO:0008271 secondary active sulfate transmembrane transporter activity(GO:0008271)
0.1 0.3 GO:0035877 death effector domain binding(GO:0035877)
0.1 0.3 GO:0015111 iodide transmembrane transporter activity(GO:0015111)
0.1 0.2 GO:0034875 testosterone 16-alpha-hydroxylase activity(GO:0008390) oxidoreductase activity, acting on CH or CH2 groups, quinone or similar compound as acceptor(GO:0033695) caffeine oxidase activity(GO:0034875)
0.1 0.3 GO:0005223 intracellular cGMP activated cation channel activity(GO:0005223)
0.1 1.4 GO:0005540 hyaluronic acid binding(GO:0005540)
0.1 0.5 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.1 0.4 GO:0004908 interleukin-1 receptor activity(GO:0004908)
0.1 0.8 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.1 0.8 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.4 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.0 0.2 GO:0050632 propanoyl-CoA C-acyltransferase activity(GO:0033814) propionyl-CoA C2-trimethyltridecanoyltransferase activity(GO:0050632) phosphatidylethanolamine transporter activity(GO:1904121)
0.0 1.5 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 0.5 GO:0030274 LIM domain binding(GO:0030274)
0.0 4.7 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.3 GO:0019864 IgG binding(GO:0019864)
0.0 1.0 GO:0005402 sugar:proton symporter activity(GO:0005351) cation:sugar symporter activity(GO:0005402)
0.0 1.5 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.6 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.4 GO:0008392 arachidonic acid epoxygenase activity(GO:0008392)
0.0 1.7 GO:0035255 ionotropic glutamate receptor binding(GO:0035255)
0.0 0.1 GO:0034437 glycoprotein transporter activity(GO:0034437)
0.0 0.1 GO:0004859 phospholipase inhibitor activity(GO:0004859)
0.0 0.2 GO:1901702 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 0.3 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.5 GO:0042288 MHC class I protein binding(GO:0042288)
0.0 0.3 GO:0005549 odorant binding(GO:0005549)
0.0 0.1 GO:0005128 erythropoietin receptor binding(GO:0005128)
0.0 1.9 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.5 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.1 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 2.4 GO:0030165 PDZ domain binding(GO:0030165)
0.0 0.9 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.2 GO:0098748 clathrin adaptor activity(GO:0035615) endocytic adaptor activity(GO:0098748)
0.0 0.4 GO:0031489 myosin V binding(GO:0031489)
0.0 0.1 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.8 GO:0031624 ubiquitin conjugating enzyme binding(GO:0031624)
0.0 0.2 GO:0042166 acetylcholine-gated cation channel activity(GO:0022848) acetylcholine binding(GO:0042166)
0.0 0.2 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 0.2 GO:0004861 cyclin-dependent protein serine/threonine kinase inhibitor activity(GO:0004861)
0.0 0.1 GO:0015205 purine nucleobase transmembrane transporter activity(GO:0005345) pyrimidine nucleobase transmembrane transporter activity(GO:0005350) nucleobase transmembrane transporter activity(GO:0015205)
0.0 0.2 GO:0015643 toxic substance binding(GO:0015643)
0.0 1.6 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.8 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 0.4 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.5 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 8.0 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 1.4 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 3.3 PID P73PATHWAY p73 transcription factor network
0.0 0.3 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.2 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.8 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.9 PID ERBB4 PATHWAY ErbB4 signaling events
0.0 0.3 PID CONE PATHWAY Visual signal transduction: Cones
0.0 1.0 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 0.6 PID FGF PATHWAY FGF signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.1 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.3 5.6 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 0.8 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.1 0.9 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.1 1.4 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.1 0.7 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 1.3 REACTOME FGFR LIGAND BINDING AND ACTIVATION Genes involved in FGFR ligand binding and activation
0.0 0.8 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.9 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 1.7 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.0 1.5 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.4 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 0.2 REACTOME RECYCLING OF BILE ACIDS AND SALTS Genes involved in Recycling of bile acids and salts
0.0 0.9 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 1.0 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.3 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.2 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 1.0 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.0 0.4 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.2 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.0 0.3 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.2 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.2 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.4 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.1 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.1 REACTOME COMMON PATHWAY Genes involved in Common Pathway