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2D miR_HR1_12

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Results for Hoxb8_Pdx1

Z-value: 0.79

Motif logo

Transcription factors associated with Hoxb8_Pdx1

Gene Symbol Gene ID Gene Info
ENSMUSG00000056648.4 homeobox B8
ENSMUSG00000029644.6 pancreatic and duodenal homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Hoxb8mm10_v2_chr11_+_96282529_96282556-0.471.2e-01Click!
Pdx1mm10_v2_chr5_+_147269959_147270102-0.049.1e-01Click!

Activity profile of Hoxb8_Pdx1 motif

Sorted Z-values of Hoxb8_Pdx1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr11_-_58613481 3.03 ENSMUST00000048801.7
RIKEN cDNA 2210407C18 gene
chr7_+_131032061 2.54 ENSMUST00000084509.3
deleted in malignant brain tumors 1
chr3_-_20275659 1.46 ENSMUST00000011607.5
carboxypeptidase B1 (tissue)
chr16_-_23890805 1.27 ENSMUST00000004480.3
somatostatin
chr1_-_9967932 1.00 ENSMUST00000185184.1
transcription factor 24
chrX_+_134295225 0.99 ENSMUST00000037687.7
transmembrane protein 35
chr15_+_31224371 0.97 ENSMUST00000044524.9
death-associated protein
chr13_+_48513570 0.89 ENSMUST00000065465.1
RIKEN cDNA A830005F24 gene
chr7_+_35802593 0.86 ENSMUST00000052454.2
RIKEN cDNA E130304I02 gene
chr13_-_3945349 0.82 ENSMUST00000058610.7
urocortin 3
chr12_+_58211772 0.80 ENSMUST00000110671.2
ENSMUST00000044299.2
somatostatin receptor 1
chr11_-_49113757 0.72 ENSMUST00000060398.1
olfactory receptor 1396
chr17_+_39846958 0.72 ENSMUST00000182010.1
predicted gene, 26924
chr2_+_91082362 0.69 ENSMUST00000169852.1
spleen focus forming virus (SFFV) proviral integration oncogene
chr16_+_96361654 0.67 ENSMUST00000113794.1
immunoglobulin superfamily, member 5
chr1_-_45503282 0.67 ENSMUST00000086430.4
collagen, type V, alpha 2
chr7_+_43995833 0.62 ENSMUST00000007156.4
kallikrein 1-related peptidase b11
chrX_+_49463926 0.59 ENSMUST00000130558.1
Rho GTPase activating protein 36
chr6_-_3399545 0.55 ENSMUST00000120087.3
sterile alpha motif domain containing 9-like
chr1_-_126830632 0.54 ENSMUST00000112583.1
ENSMUST00000094609.3
NCK-associated protein 5
chr7_+_6995443 0.53 ENSMUST00000086248.5
aurora kinase C
chr4_+_100776664 0.53 ENSMUST00000030257.8
ENSMUST00000097955.2
cache domain containing 1
chr1_-_120271074 0.53 ENSMUST00000112641.1
STEAP family member 3
chr19_-_34166037 0.53 ENSMUST00000025686.7
ankyrin repeat domain 22
chr4_-_35157404 0.52 ENSMUST00000102975.3
MOB kinase activator 3B
chr1_-_164935522 0.50 ENSMUST00000027860.7
chemokine (C motif) ligand 1
chr6_+_124304646 0.49 ENSMUST00000112541.2
ENSMUST00000032234.2
CD163 antigen
chr14_+_55560480 0.48 ENSMUST00000121622.1
ENSMUST00000143431.1
ENSMUST00000150481.1
DDB1 and CUL4 associated factor 11
chr1_+_88134786 0.47 ENSMUST00000113134.1
ENSMUST00000140092.1
UDP glucuronosyltransferase 1 family, polypeptide A6A
chr2_-_164221605 0.46 ENSMUST00000018355.4
ENSMUST00000109376.2
WAP four-disulfide core domain 15B
chr1_+_88103229 0.45 ENSMUST00000113135.3
ENSMUST00000113138.1
UDP glucuronosyltransferase 1 family, polypeptide A6A
UDP glucuronosyltransferase 1 family, polypeptide A6B
chr2_+_125136692 0.44 ENSMUST00000099452.2
cortexin 2
chr14_-_34374617 0.43 ENSMUST00000023826.4
synuclein, gamma
chr11_-_69695802 0.43 ENSMUST00000108649.1
ENSMUST00000174159.1
ENSMUST00000181810.1
cDNA sequence BC096441
tumor necrosis factor (ligand) superfamily, member 12
chr13_-_23914998 0.43 ENSMUST00000021769.8
ENSMUST00000110407.2
solute carrier family 17 (sodium phosphate), member 4
chr11_-_99244058 0.43 ENSMUST00000103132.3
ENSMUST00000038214.6
keratin 222
chr3_-_59130610 0.42 ENSMUST00000065220.6
ENSMUST00000091112.4
purinergic receptor P2Y, G-protein coupled, 14
chr17_+_55892184 0.42 ENSMUST00000054780.8
zinc finger protein 959
chr5_+_20702129 0.42 ENSMUST00000101556.4
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr12_+_108334341 0.41 ENSMUST00000021684.4
cytochrome P450, family 46, subfamily a, polypeptide 1
chr3_-_65392579 0.41 ENSMUST00000029414.5
signal sequence receptor, gamma
chr6_+_96115249 0.41 ENSMUST00000075080.5
family with sequence similarity 19, member A1
chr4_+_102589687 0.41 ENSMUST00000097949.4
ENSMUST00000106901.1
phosphodiesterase 4B, cAMP specific
chr11_-_69695521 0.40 ENSMUST00000181261.1
tumor necrosis factor (ligand) superfamily, member 12
chr6_-_52012476 0.40 ENSMUST00000078214.5
src family associated phosphoprotein 2
chr3_-_107943705 0.39 ENSMUST00000106680.1
ENSMUST00000106684.1
ENSMUST00000106685.2
glutathione S-transferase, mu 6
chr4_-_42168603 0.39 ENSMUST00000098121.3
predicted gene 13305
chr17_+_37193889 0.38 ENSMUST00000038844.6
ubiquitin D
chr6_+_4755327 0.38 ENSMUST00000176551.1
paternally expressed 10
chr11_-_69695753 0.38 ENSMUST00000180946.1
tumor necrosis factor (ligand) superfamily, member 12
chr10_+_57784859 0.38 ENSMUST00000020024.5
fatty acid binding protein 7, brain
chr14_+_55560904 0.37 ENSMUST00000072530.4
ENSMUST00000128490.1
DDB1 and CUL4 associated factor 11
chr6_+_128662379 0.37 ENSMUST00000032518.4
C-type lectin domain family 2, member h
chr11_-_52213987 0.36 ENSMUST00000075844.3
olfactory receptor 1371
chr12_+_109747903 0.35 ENSMUST00000183084.1
ENSMUST00000182300.1
miRNA containing gene
chr14_-_55560340 0.34 ENSMUST00000066106.3
RIKEN cDNA A730061H03 gene
chr4_+_102421518 0.33 ENSMUST00000106904.2
phosphodiesterase 4B, cAMP specific
chr18_-_10706688 0.33 ENSMUST00000002549.7
ENSMUST00000117726.1
ENSMUST00000117828.1
abhydrolase domain containing 3
chr17_-_53539411 0.32 ENSMUST00000056198.3
protein phosphatase 2C-like domain containing 1
chr1_-_162898484 0.32 ENSMUST00000143123.1
flavin containing monooxygenase 2
chr6_-_138421379 0.31 ENSMUST00000163065.1
LIM domain only 3
chr7_-_12818837 0.31 ENSMUST00000121215.1
ENSMUST00000108546.1
ENSMUST00000072222.7
zinc finger protein 329
chr2_+_122637867 0.31 ENSMUST00000110512.3
expressed sequence AA467197
chr1_-_36273425 0.30 ENSMUST00000056946.6
neuralized homolog 3 homolog (Drosophila)
chr4_+_43441939 0.30 ENSMUST00000060864.6
testis specific protein kinase 1
chr1_-_162866502 0.30 ENSMUST00000046049.7
flavin containing monooxygenase 1
chr10_-_53694823 0.29 ENSMUST00000171807.1
family with sequence similarity 184, member A
chr2_+_174285352 0.29 ENSMUST00000130761.1
GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus
chr1_+_130826762 0.29 ENSMUST00000133792.1
polymeric immunoglobulin receptor
chr4_+_128058962 0.29 ENSMUST00000184063.1
CUB and Sushi multiple domains 2
chr17_-_34862473 0.29 ENSMUST00000025229.4
ENSMUST00000176203.2
ENSMUST00000128767.1
complement factor B
chr6_-_52208694 0.28 ENSMUST00000062829.7
homeobox A6
chr19_+_45076105 0.28 ENSMUST00000026234.4
Kazal-type serine peptidase inhibitor domain 1
chr7_+_24257644 0.28 ENSMUST00000072713.6
zinc finger protein 108
chr4_+_33924632 0.28 ENSMUST00000057188.6
cannabinoid receptor 1 (brain)
chr4_+_102254993 0.27 ENSMUST00000106908.2
phosphodiesterase 4B, cAMP specific
chr8_+_13435459 0.27 ENSMUST00000167071.1
ENSMUST00000167505.1
transmembrane protein 255B
chr15_+_87625214 0.27 ENSMUST00000068088.6
family with sequence similarity 19, member A5
chr2_-_5063996 0.26 ENSMUST00000114996.1
optineurin
chrX_-_106011874 0.26 ENSMUST00000033583.7
ENSMUST00000151689.1
magnesium transporter 1
chr14_+_55559993 0.26 ENSMUST00000117236.1
DDB1 and CUL4 associated factor 11
chr1_-_120270253 0.26 ENSMUST00000112639.1
STEAP family member 3
chrX_+_71962971 0.26 ENSMUST00000048790.6
proline rich Gla (G-carboxyglutamic acid) 3 (transmembrane)
chr2_-_116067391 0.26 ENSMUST00000140185.1
RIKEN cDNA 2700033N17 gene
chr2_+_158375638 0.25 ENSMUST00000109488.1
small nucleolar RNA host gene 11
chr4_-_43653560 0.25 ENSMUST00000107870.2
sperm associated antigen 8
chr10_+_42678890 0.25 ENSMUST00000040718.5
osteopetrosis associated transmembrane protein 1
chr4_-_43653542 0.25 ENSMUST00000084646.4
sperm associated antigen 8
chr11_-_69696058 0.25 ENSMUST00000180587.1
ENSMUST00000094070.4
tumor necrosis factor (ligand) superfamily, member 12
cDNA sequence BC096441
chr6_+_106118924 0.25 ENSMUST00000079416.5
contactin 4
chr5_-_109558957 0.25 ENSMUST00000044579.7
cytokine receptor-like factor 2
chr9_+_59589288 0.25 ENSMUST00000121266.1
ENSMUST00000118164.1
CUGBP, Elav-like family member 6
chr3_-_69859875 0.24 ENSMUST00000051239.7
ENSMUST00000171529.1
serine palmitoyltransferase, small subunit B
chr3_+_135281221 0.23 ENSMUST00000120397.1
ENSMUST00000171974.1
ENSMUST00000029817.7
3-hydroxybutyrate dehydrogenase, type 2
chr10_-_128744014 0.23 ENSMUST00000026414.7
diacylglycerol kinase, alpha
chr4_+_101717404 0.23 ENSMUST00000102777.3
ENSMUST00000106921.2
ENSMUST00000037552.3
ENSMUST00000145024.1
leptin receptor
chr3_-_65392546 0.23 ENSMUST00000119896.1
signal sequence receptor, gamma
chr3_-_79145875 0.23 ENSMUST00000118340.1
Rap guanine nucleotide exchange factor (GEF) 2
chr4_+_147492417 0.22 ENSMUST00000105721.2
predicted gene 13152
chr13_+_58281183 0.22 ENSMUST00000180882.1
ENSMUST00000180452.1
predicted gene, 26555
chr4_+_33062999 0.22 ENSMUST00000108162.1
ENSMUST00000024035.2
gamma-aminobutyric acid (GABA) C receptor, subunit rho 2
chr4_-_147702553 0.22 ENSMUST00000117638.1
zinc finger protein 534
chr8_+_64947177 0.21 ENSMUST00000079896.7
ENSMUST00000026595.5
transmembrane protein 192
chr1_+_46066738 0.21 ENSMUST00000069293.7
dynein, axonemal, heavy chain 7B
chr5_+_129096740 0.21 ENSMUST00000056617.7
ENSMUST00000156437.1
G protein-coupled receptor 133
chr1_+_88166004 0.21 ENSMUST00000097659.4
UDP glucuronosyltransferase 1 family, polypeptide A5
chr11_+_96323253 0.21 ENSMUST00000093944.3
homeobox B3
chr10_-_41709297 0.21 ENSMUST00000019955.9
ENSMUST00000099932.3
coiled-coil domain containing 162
chr1_-_37536232 0.21 ENSMUST00000042161.8
mannoside acetylglucosaminyltransferase 4, isoenzyme A
chr13_-_48513394 0.20 ENSMUST00000177530.1
ENSMUST00000176996.1
ENSMUST00000176949.1
ENSMUST00000176176.1
zinc finger protein 169
chrX_-_101222426 0.20 ENSMUST00000120389.1
ENSMUST00000156473.1
ENSMUST00000077876.3
sorting nexin 12
chr17_+_84957993 0.20 ENSMUST00000080217.6
ENSMUST00000112304.2
protein phosphatase 1B, magnesium dependent, beta isoform
chr13_-_113042243 0.20 ENSMUST00000099162.2
predicted gene 10735
chr9_-_119825456 0.20 ENSMUST00000070617.7
sodium channel, voltage-gated, type XI, alpha
chr2_+_126034647 0.19 ENSMUST00000064794.7
fibroblast growth factor 7
chr14_+_61599493 0.19 ENSMUST00000039562.6
tripartite motif-containing 13
chr1_+_58713241 0.19 ENSMUST00000114309.1
ENSMUST00000069333.7
CASP8 and FADD-like apoptosis regulator
chr2_+_86041317 0.19 ENSMUST00000111589.1
olfactory receptor 1033
chr15_-_101869695 0.19 ENSMUST00000087996.5
keratin 77
chr10_+_121365078 0.19 ENSMUST00000040344.6
glucosamine (N-acetyl)-6-sulfatase
chr15_+_92597104 0.19 ENSMUST00000035399.8
PDZ domain containing RING finger 4
chr6_+_37870786 0.19 ENSMUST00000120428.1
ENSMUST00000031859.7
tripartite motif-containing 24
chr3_+_65109343 0.19 ENSMUST00000159525.1
ENSMUST00000049230.8
potassium voltage-gated channel, shaker-related subfamily, beta member 1
chr17_-_35046726 0.18 ENSMUST00000097338.4
mutS homolog 5 (E. coli)
chr9_-_40984460 0.18 ENSMUST00000180872.1
cytotoxic and regulatory T cell molecule
chr4_+_116596672 0.18 ENSMUST00000051869.7
coiled-coil domain containing 17
chr5_-_87140318 0.18 ENSMUST00000067790.6
ENSMUST00000113327.1
UDP glucuronosyltransferase 2 family, polypeptide B5
chr2_+_122637844 0.18 ENSMUST00000047498.8
expressed sequence AA467197
chr2_-_72813665 0.18 ENSMUST00000136807.1
ENSMUST00000148327.1
RIKEN cDNA 6430710C18 gene
chr4_+_126024506 0.18 ENSMUST00000106162.1
colony stimulating factor 3 receptor (granulocyte)
chrX_+_73214333 0.18 ENSMUST00000156188.1
ENSMUST00000069077.3
ENSMUST00000069103.4
ENSMUST00000114506.1
ENSMUST00000081827.3
X-linked lymphocyte-regulated 4B
chr16_-_29946499 0.18 ENSMUST00000181968.1
predicted gene, 26569
chr10_+_102158858 0.18 ENSMUST00000138522.1
ENSMUST00000163753.1
ENSMUST00000138016.1
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr2_+_126034967 0.18 ENSMUST00000110442.1
fibroblast growth factor 7
chr10_+_57794335 0.17 ENSMUST00000151623.1
ENSMUST00000020022.7
sphingomyelin phosphodiesterase, acid-like 3A
chr14_+_70555900 0.17 ENSMUST00000163060.1
hairless
chr12_-_15816762 0.17 ENSMUST00000020922.7
tribbles homolog 2 (Drosophila)
chr2_+_55411790 0.17 ENSMUST00000155997.1
ENSMUST00000128307.1
predicted gene 14033
chr16_-_94370450 0.17 ENSMUST00000138514.1
phosphatidylinositol glycan anchor biosynthesis, class P
chr6_+_142298419 0.16 ENSMUST00000041993.2
islet amyloid polypeptide
chr11_-_100193246 0.16 ENSMUST00000059707.2
keratin 9
chr5_+_43233928 0.16 ENSMUST00000114066.1
ENSMUST00000114065.1
cytoplasmic polyadenylation element binding protein 2
chr2_-_175175871 0.16 ENSMUST00000109054.2
predicted gene 14443
chrX_-_73265390 0.16 ENSMUST00000080839.1
X-linked lymphocyte-regulated 3C
chr5_+_57718021 0.16 ENSMUST00000094783.3
ENSMUST00000068110.7
protocadherin 7
chr19_+_55742242 0.16 ENSMUST00000111652.1
ENSMUST00000111649.1
ENSMUST00000111651.1
ENSMUST00000111653.1
ENSMUST00000111656.1
ENSMUST00000127233.1
ENSMUST00000153888.1
transcription factor 7 like 2, T cell specific, HMG box
chr11_+_103103051 0.16 ENSMUST00000152971.1
acyl-Coenzyme A binding domain containing 4
chr3_-_57294880 0.16 ENSMUST00000171384.1
transmembrane 4 superfamily member 1
chr3_+_151437887 0.16 ENSMUST00000046977.7
EGF, latrophilin seven transmembrane domain containing 1
chr2_+_69380431 0.15 ENSMUST00000063690.3
dehydrogenase/reductase (SDR family) member 9
chr8_-_83332416 0.15 ENSMUST00000177594.1
ENSMUST00000053902.3
ELMO/CED-12 domain containing 2
chr9_+_54538984 0.15 ENSMUST00000060242.5
ENSMUST00000118413.1
SH2 domain containing 7
chr11_+_104231390 0.15 ENSMUST00000106992.3
microtubule-associated protein tau
chr7_+_46841475 0.15 ENSMUST00000147535.1
lactate dehydrogenase A
chrX_+_8803691 0.15 ENSMUST00000089370.5
synovial sarcoma, X member B, breakpoint 5
chrX_-_7572843 0.14 ENSMUST00000132788.1
protein phosphatase 1, regulatory (inhibitor) subunit 3F
chr6_-_56369625 0.14 ENSMUST00000170774.1
ENSMUST00000168944.1
ENSMUST00000166890.1
phosphodiesterase 1C
chr13_+_94083490 0.14 ENSMUST00000156071.1
lipoma HMGIC fusion partner-like 2
chr5_+_43233463 0.14 ENSMUST00000169035.1
ENSMUST00000166713.1
cytoplasmic polyadenylation element binding protein 2
chr8_+_34807287 0.14 ENSMUST00000033930.4
dual specificity phosphatase 4
chr14_-_21989475 0.14 ENSMUST00000043409.7
zinc finger protein 503
chr1_-_187215421 0.14 ENSMUST00000110945.3
ENSMUST00000183931.1
ENSMUST00000027908.6
spermatogenesis associated 17
chr2_+_128863921 0.14 ENSMUST00000028864.2
fibulin 7
chr7_-_43505926 0.14 ENSMUST00000013497.1
ENSMUST00000163619.1
RIKEN cDNA 4931406B18 gene
chrX_+_163911401 0.13 ENSMUST00000140845.1
adaptor-related protein complex 1, sigma 2 subunit
chr10_+_102159000 0.13 ENSMUST00000020039.6
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr4_-_3872105 0.13 ENSMUST00000105158.1
Moloney sarcoma oncogene
chr7_-_3720382 0.13 ENSMUST00000078451.6
paired Ig-like receptor B
chr8_-_105565985 0.13 ENSMUST00000013304.7
ATPase, H+ transporting, lysosomal V0 subunit D1
chr17_-_34862122 0.13 ENSMUST00000154526.1
complement factor B
chr15_+_82341179 0.13 ENSMUST00000050349.2
family with sequence similarity 109, member B
chr11_-_96977660 0.13 ENSMUST00000107626.1
ENSMUST00000107624.1
Sp2 transcription factor
chr15_-_42676967 0.13 ENSMUST00000022921.5
angiopoietin 1
chr1_-_119053339 0.13 ENSMUST00000161301.1
ENSMUST00000161451.1
ENSMUST00000162607.1
GLI-Kruppel family member GLI2
chr7_+_44384098 0.13 ENSMUST00000118962.1
ENSMUST00000118831.1
synaptotagmin III
chr5_-_24329556 0.13 ENSMUST00000115098.2
potassium voltage-gated channel, subfamily H (eag-related), member 2
chr1_+_72583245 0.13 ENSMUST00000145868.1
ENSMUST00000133123.1
ENSMUST00000047615.8
SWI/SNF related matrix associated, actin dependent regulator of chromatin, subfamily a-like 1
chr16_+_24721842 0.12 ENSMUST00000115314.2
LIM domain containing preferred translocation partner in lipoma
chr9_+_121710389 0.12 ENSMUST00000035113.9
differentially expressed in B16F10 1
chr1_+_109983737 0.12 ENSMUST00000172005.1
cadherin 7, type 2
chr19_-_3575708 0.12 ENSMUST00000113997.2
ENSMUST00000025846.8
ENSMUST00000172362.1
protein phosphatase 6, regulatory subunit 3
chr19_-_57197556 0.12 ENSMUST00000099294.2
actin-binding LIM protein 1
chr7_+_103979176 0.12 ENSMUST00000098185.1
olfactory receptor 635
chr1_-_119053619 0.12 ENSMUST00000062483.8
GLI-Kruppel family member GLI2
chr3_-_116968827 0.12 ENSMUST00000119557.1
palmdelphin
chr11_+_104231515 0.11 ENSMUST00000106993.3
microtubule-associated protein tau
chr3_+_19957037 0.11 ENSMUST00000091309.5
ENSMUST00000108329.1
ENSMUST00000003714.6
ceruloplasmin
chr8_+_118283719 0.11 ENSMUST00000117160.1
cadherin 13
chr4_-_109202217 0.11 ENSMUST00000160774.1
ENSMUST00000030288.7
ENSMUST00000162787.2
oxysterol binding protein-like 9
chr5_-_87424201 0.11 ENSMUST00000072818.5
UDP glucuronosyltransferase 2 family, polypeptide B38
chr4_-_150003130 0.11 ENSMUST00000084117.6
hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
chr6_+_21215472 0.11 ENSMUST00000081542.5
potassium voltage-gated channel, Shal-related family, member 2
chr17_-_35046539 0.11 ENSMUST00000007250.7
mutS homolog 5 (E. coli)
chr9_+_99243421 0.11 ENSMUST00000093795.3
centrosomal protein 70
chr16_+_90738324 0.11 ENSMUST00000038197.2
melanocortin 2 receptor accessory protein
chr15_+_76457438 0.11 ENSMUST00000043089.7
scleraxis
chr9_-_118014160 0.11 ENSMUST00000111769.3
zinc finger, CW type with PWWP domain 2
chr11_+_49247462 0.11 ENSMUST00000109194.1
mannoside acetylglucosaminyltransferase 1
chr6_-_21851914 0.10 ENSMUST00000134635.1
ENSMUST00000123116.1
ENSMUST00000120965.1
tetraspanin 12
chr11_+_96271453 0.10 ENSMUST00000000010.8
ENSMUST00000174042.1
homeobox B9

Network of associatons between targets according to the STRING database.

First level regulatory network of Hoxb8_Pdx1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.2 0.5 GO:2000412 immunoglobulin production in mucosal tissue(GO:0002426) granzyme B production(GO:0071613) regulation of granzyme B production(GO:0071661) positive regulation of granzyme B production(GO:0071663) regulation of thymocyte migration(GO:2000410) positive regulation of thymocyte migration(GO:2000412) regulation of B cell chemotaxis(GO:2000537) positive regulation of B cell chemotaxis(GO:2000538) regulation of T-helper 1 cell cytokine production(GO:2000554) positive regulation of T-helper 1 cell cytokine production(GO:2000556) positive regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000563)
0.2 0.8 GO:1902167 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902167)
0.1 0.7 GO:0045347 negative regulation of MHC class II biosynthetic process(GO:0045347)
0.1 2.5 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.1 0.4 GO:0061033 secretion by lung epithelial cell involved in lung growth(GO:0061033)
0.1 0.4 GO:0035589 G-protein coupled purinergic nucleotide receptor signaling pathway(GO:0035589)
0.1 1.1 GO:0052697 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.1 1.0 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1 0.2 GO:0060032 spinal cord ventral commissure morphogenesis(GO:0021965) notochord regression(GO:0060032)
0.1 0.5 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.1 0.4 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.1 0.2 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.1 0.2 GO:2000670 positive regulation of dendritic cell apoptotic process(GO:2000670)
0.1 0.3 GO:0002415 immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
0.1 0.3 GO:0099553 trans-synaptic signaling by lipid, modulating synaptic transmission(GO:0099552) trans-synaptic signaling by endocannabinoid, modulating synaptic transmission(GO:0099553)
0.1 0.2 GO:2000642 negative regulation of early endosome to late endosome transport(GO:2000642)
0.1 0.3 GO:0072592 oxygen metabolic process(GO:0072592)
0.1 0.2 GO:0001868 regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
0.1 0.2 GO:0002355 detection of tumor cell(GO:0002355)
0.1 0.2 GO:0042091 interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.1 0.3 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.0 0.7 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 0.2 GO:1903943 skeletal muscle atrophy(GO:0014732) negative regulation of myoblast fusion(GO:1901740) regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.0 0.4 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.0 0.1 GO:0070315 G1 to G0 transition involved in cell differentiation(GO:0070315)
0.0 0.5 GO:0051255 spindle midzone assembly(GO:0051255)
0.0 0.1 GO:1901993 meiotic cell cycle phase transition(GO:0044771) regulation of meiotic cell cycle phase transition(GO:1901993) negative regulation of meiotic cell cycle phase transition(GO:1901994)
0.0 0.3 GO:0045900 negative regulation of translational elongation(GO:0045900)
0.0 0.1 GO:0030210 heparin biosynthetic process(GO:0030210)
0.0 0.3 GO:1900034 regulation of cellular response to heat(GO:1900034)
0.0 0.2 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
0.0 0.2 GO:0006499 N-terminal protein myristoylation(GO:0006499)
0.0 0.6 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.0 0.4 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.1 GO:1902303 negative regulation of potassium ion export(GO:1902303)
0.0 0.1 GO:0014809 regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion(GO:0014809)
0.0 0.1 GO:0000733 DNA strand renaturation(GO:0000733)
0.0 0.2 GO:1904220 regulation of serine C-palmitoyltransferase activity(GO:1904220)
0.0 0.1 GO:0034971 histone H3-R17 methylation(GO:0034971)
0.0 0.4 GO:0060134 prepulse inhibition(GO:0060134)
0.0 0.1 GO:0019244 fermentation(GO:0006113) lactate biosynthetic process from pyruvate(GO:0019244) glucose catabolic process to lactate(GO:0019659) glycolytic fermentation(GO:0019660) glucose catabolic process to lactate via pyruvate(GO:0019661)
0.0 0.2 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.0 0.3 GO:0070995 NADPH oxidation(GO:0070995)
0.0 0.3 GO:0051026 chiasma assembly(GO:0051026)
0.0 0.2 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.0 0.1 GO:0061056 sclerotome development(GO:0061056)
0.0 0.1 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.0 1.7 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 0.1 GO:0021524 visceral motor neuron differentiation(GO:0021524)
0.0 0.1 GO:0055096 lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096)
0.0 0.2 GO:0035745 T-helper 2 cell cytokine production(GO:0035745)
0.0 0.2 GO:0097647 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.0 1.0 GO:0034198 cellular response to amino acid starvation(GO:0034198)
0.0 0.2 GO:0006654 phosphatidic acid biosynthetic process(GO:0006654)
0.0 0.1 GO:0003275 apoptotic process involved in outflow tract morphogenesis(GO:0003275) regulation of apoptotic process involved in outflow tract morphogenesis(GO:1902256)
0.0 0.2 GO:0048625 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) embryonic genitalia morphogenesis(GO:0030538) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334) embryonic hindgut morphogenesis(GO:0048619) myoblast fate commitment(GO:0048625)
0.0 0.1 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.0 0.1 GO:0030916 otic vesicle formation(GO:0030916)
0.0 0.1 GO:0060672 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.0 1.5 GO:0007608 sensory perception of smell(GO:0007608)
0.0 0.0 GO:0046005 positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
0.0 0.0 GO:0035938 estradiol secretion(GO:0035938) regulation of estradiol secretion(GO:2000864)
0.0 0.1 GO:0034285 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.0 0.1 GO:0045590 negative regulation of regulatory T cell differentiation(GO:0045590)
0.0 0.2 GO:0016127 cholesterol catabolic process(GO:0006707) sterol catabolic process(GO:0016127)
0.0 0.1 GO:0019364 pyridine nucleotide catabolic process(GO:0019364)
0.0 0.1 GO:0044778 meiotic DNA integrity checkpoint(GO:0044778)
0.0 0.0 GO:0002018 renin-angiotensin regulation of aldosterone production(GO:0002018)
0.0 0.4 GO:0014046 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.0 0.2 GO:0006968 cellular defense response(GO:0006968)
0.0 1.1 GO:2001238 positive regulation of extrinsic apoptotic signaling pathway(GO:2001238)
0.0 0.2 GO:0036159 inner dynein arm assembly(GO:0036159)
0.0 0.0 GO:0080154 regulation of fertilization(GO:0080154)
0.0 0.1 GO:0070672 response to interleukin-15(GO:0070672)
0.0 0.3 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.1 GO:2000465 regulation of glycogen (starch) synthase activity(GO:2000465)
0.0 0.0 GO:0003127 detection of nodal flow(GO:0003127) detection of endogenous stimulus(GO:0009726)
0.0 0.1 GO:2000195 negative regulation of female gonad development(GO:2000195)
0.0 0.1 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.2 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.0 0.0 GO:0014719 skeletal muscle satellite cell activation(GO:0014719)
0.0 0.2 GO:1902187 negative regulation of viral release from host cell(GO:1902187)
0.0 0.1 GO:0036295 cellular response to increased oxygen levels(GO:0036295)
0.0 0.5 GO:0006953 acute-phase response(GO:0006953)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.5 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.2 0.7 GO:0005588 collagen type V trimer(GO:0005588)
0.1 0.5 GO:0032133 chromosome passenger complex(GO:0032133)
0.1 0.2 GO:0044299 C-fiber(GO:0044299)
0.0 1.0 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.8 GO:0043196 varicosity(GO:0043196)
0.0 0.2 GO:0031211 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.2 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.0 0.1 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.0 1.2 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.2 GO:0005726 perichromatin fibrils(GO:0005726)
0.0 0.4 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.8 GO:0005771 multivesicular body(GO:0005771)
0.0 0.2 GO:0097542 ciliary tip(GO:0097542)
0.0 0.3 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.3 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.2 GO:0070369 beta-catenin-TCF7L2 complex(GO:0070369)
0.0 0.1 GO:0045298 tubulin complex(GO:0045298)
0.0 0.2 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.4 GO:0045095 keratin filament(GO:0045095)
0.0 0.7 GO:0000795 synaptonemal complex(GO:0000795)
0.0 0.3 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.2 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.4 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.2 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 0.3 GO:0097038 perinuclear endoplasmic reticulum(GO:0097038)
0.0 0.3 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.1 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0004994 somatostatin receptor activity(GO:0004994)
0.1 1.1 GO:0051429 corticotropin-releasing hormone receptor binding(GO:0051429)
0.1 0.3 GO:0052740 phosphatidylserine 1-acylhydrolase activity(GO:0052739) 1-acyl-2-lysophosphatidylserine acylhydrolase activity(GO:0052740)
0.1 0.8 GO:0008823 ferric-chelate reductase activity(GO:0000293) cupric reductase activity(GO:0008823) ferric-chelate reductase (NADPH) activity(GO:0052851)
0.1 0.6 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.1 0.2 GO:0003858 3-hydroxybutyrate dehydrogenase activity(GO:0003858)
0.1 0.4 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.1 0.6 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1 0.3 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.1 1.0 GO:0070513 death domain binding(GO:0070513)
0.1 3.1 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 0.2 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1 0.4 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 0.7 GO:0051525 NFAT protein binding(GO:0051525)
0.1 0.5 GO:0035174 histone serine kinase activity(GO:0035174)
0.1 1.5 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.1 GO:2001069 glycogen binding(GO:2001069)
0.0 0.3 GO:0099609 microtubule lateral binding(GO:0099609)
0.0 0.1 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 1.4 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.5 GO:0005436 sodium:phosphate symporter activity(GO:0005436)
0.0 0.2 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.1 GO:0047936 glucose 1-dehydrogenase [NAD(P)] activity(GO:0047936)
0.0 0.1 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 1.5 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.1 GO:0070996 type 1 melanocortin receptor binding(GO:0070996)
0.0 0.3 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.0 1.2 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.4 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.2 GO:0047035 testosterone dehydrogenase (NAD+) activity(GO:0047035)
0.0 0.3 GO:0030983 mismatched DNA binding(GO:0030983)
0.0 0.3 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.0 0.2 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.2 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 1.3 GO:0004984 olfactory receptor activity(GO:0004984)
0.0 0.2 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.1 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.0 0.4 GO:0046703 natural killer cell lectin-like receptor binding(GO:0046703)
0.0 0.2 GO:0016500 protein-hormone receptor activity(GO:0016500)
0.0 0.1 GO:1902282 voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282)
0.0 0.2 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.0 0.1 GO:0001595 angiotensin receptor activity(GO:0001595)
0.0 0.1 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.1 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.0 0.3 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.1 GO:0004948 calcitonin receptor activity(GO:0004948)
0.0 0.3 GO:0004576 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.4 GO:0070628 proteasome binding(GO:0070628)
0.0 0.1 GO:0055100 adiponectin binding(GO:0055100)
0.0 0.1 GO:0038181 bile acid receptor activity(GO:0038181)
0.0 0.1 GO:0001517 N-acetylglucosamine 6-O-sulfotransferase activity(GO:0001517)
0.0 0.2 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 1.5 GO:0005179 hormone activity(GO:0005179)
0.0 0.2 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.4 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.0 0.5 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.4 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.0 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.0 0.0 GO:0004335 galactokinase activity(GO:0004335)
0.0 0.2 GO:0042809 vitamin D receptor binding(GO:0042809)
0.0 0.1 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.0 0.1 GO:0036310 annealing helicase activity(GO:0036310)
0.0 0.2 GO:0070402 NADPH binding(GO:0070402)
0.0 0.1 GO:0050694 galactose 3-O-sulfotransferase activity(GO:0050694)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.3 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.4 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.6 PID AURORA B PATHWAY Aurora B signaling
0.0 1.0 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 2.2 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.0 0.4 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.4 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.9 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.0 0.6 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 1.0 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.4 REACTOME ACTIVATED POINT MUTANTS OF FGFR2 Genes involved in Activated point mutants of FGFR2
0.0 0.6 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 0.4 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.2 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.2 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 2.6 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 0.2 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.1 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.2 REACTOME IRON UPTAKE AND TRANSPORT Genes involved in Iron uptake and transport
0.0 0.3 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.4 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.3 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.4 REACTOME PROSTACYCLIN SIGNALLING THROUGH PROSTACYCLIN RECEPTOR Genes involved in Prostacyclin signalling through prostacyclin receptor