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2D miR_HR1_12

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Results for Hif1a

Z-value: 0.62

Motif logo

Transcription factors associated with Hif1a

Gene Symbol Gene ID Gene Info
ENSMUSG00000021109.7 hypoxia inducible factor 1, alpha subunit

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Hif1amm10_v2_chr12_+_73907904_739079700.215.0e-01Click!

Activity profile of Hif1a motif

Sorted Z-values of Hif1a motif

Promoter Log-likelihood Transcript Gene Gene Info
chr2_+_127336152 1.24 ENSMUST00000028846.6
dual specificity phosphatase 2
chr5_-_135251209 1.00 ENSMUST00000062572.2
frizzled homolog 9 (Drosophila)
chr1_+_172481788 0.72 ENSMUST00000127052.1
immunoglobulin superfamily, member 9
chr1_+_172482199 0.70 ENSMUST00000135267.1
ENSMUST00000052629.6
ENSMUST00000111235.2
immunoglobulin superfamily, member 9
chr11_-_72411695 0.67 ENSMUST00000108500.1
ENSMUST00000050226.6
smoothelin-like 2
chr2_+_71873224 0.62 ENSMUST00000006669.5
pyruvate dehydrogenase kinase, isoenzyme 1
chr4_-_136956784 0.61 ENSMUST00000030420.8
Eph receptor A8
chr8_+_106893616 0.60 ENSMUST00000047629.5
cirrhosis, autosomal recessive 1A (human)
chr14_+_5501674 0.57 ENSMUST00000181562.1
predicted gene, 3488
chr2_-_14055963 0.54 ENSMUST00000091429.5
ENSMUST00000114753.1
protein tyrosine phosphatase-like (proline instead of catalytic arginine), member a
chr14_+_3652030 0.54 ENSMUST00000167430.1
predicted gene 3020
chr10_-_59951753 0.52 ENSMUST00000020308.3
DNA-damage-inducible transcript 4
chr7_-_99182681 0.52 ENSMUST00000033001.4
diacylglycerol O-acyltransferase 2
chr11_+_78178651 0.52 ENSMUST00000092880.7
ENSMUST00000127587.1
ENSMUST00000108338.1
TLC domain containing 1
chr5_+_125441546 0.50 ENSMUST00000049040.9
Bri3 binding protein
chr14_+_4334763 0.50 ENSMUST00000165466.1
RIKEN cDNA 2610042L04 gene
chr17_-_26201363 0.49 ENSMUST00000121959.1
Rho GDP dissociation inhibitor (GDI) gamma
chr15_-_36608959 0.48 ENSMUST00000001809.8
poly(A) binding protein, cytoplasmic 1
chr14_-_68124836 0.46 ENSMUST00000111089.1
ENSMUST00000022638.5
neurofilament, medium polypeptide
chr2_-_14056029 0.46 ENSMUST00000074854.7
protein tyrosine phosphatase-like (proline instead of catalytic arginine), member a
chr1_-_75180349 0.45 ENSMUST00000027396.8
ATP-binding cassette, sub-family B (MDR/TAP), member 6
chr1_-_55088156 0.45 ENSMUST00000127861.1
ENSMUST00000144077.1
heat shock protein 1 (chaperonin)
chrX_+_159414572 0.43 ENSMUST00000112471.2
MAP7 domain containing 2
chr14_-_6287250 0.43 ENSMUST00000170104.2
predicted gene 3411
chr14_-_31019055 0.43 ENSMUST00000037739.6
guanine nucleotide binding protein-like 3 (nucleolar)
chr7_+_16310412 0.42 ENSMUST00000136781.1
BCL2 binding component 3
chr6_+_125131869 0.41 ENSMUST00000044200.8
NOP2 nucleolar protein
chr9_+_107587711 0.41 ENSMUST00000010192.5
interferon-related developmental regulator 2
chr7_-_45466894 0.41 ENSMUST00000033093.8
BCL2-associated X protein
chr2_+_30807826 0.40 ENSMUST00000041830.3
ENSMUST00000152374.1
N-terminal Xaa-Pro-Lys N-methyltransferase 1
chr11_+_3332426 0.39 ENSMUST00000136474.1
phosphoinositide-3-kinase interacting protein 1
chr4_-_139352298 0.39 ENSMUST00000030513.6
ENSMUST00000155257.1
MRT4, mRNA turnover 4, homolog (S. cerevisiae)
chr4_-_139352538 0.38 ENSMUST00000102503.3
MRT4, mRNA turnover 4, homolog (S. cerevisiae)
chr14_-_7027449 0.38 ENSMUST00000170738.2
predicted gene 10406
chr19_+_45006475 0.37 ENSMUST00000026227.2
progressive external ophthalmoplegia 1 (human)
chr5_+_33658123 0.35 ENSMUST00000074849.6
ENSMUST00000079534.4
transforming, acidic coiled-coil containing protein 3
chr14_+_33319703 0.35 ENSMUST00000111955.1
Rho GTPase activating protein 22
chr4_+_150236816 0.34 ENSMUST00000080926.6
enolase 1, alpha non-neuron
chr4_+_150236685 0.34 ENSMUST00000150175.1
enolase 1, alpha non-neuron
chr4_+_152325831 0.34 ENSMUST00000103191.4
ENSMUST00000139685.1
ribosomal protein L22
chr4_-_129600586 0.34 ENSMUST00000135055.1
eukaryotic translation initiation factor 3, subunit I
chr5_+_110653444 0.33 ENSMUST00000031478.5
DEAD (Asp-Glu-Ala-Asp) box polypeptide 51
chr4_+_11191354 0.32 ENSMUST00000170901.1
cyclin E2
chr11_-_77489666 0.32 ENSMUST00000037593.7
ENSMUST00000092892.3
ankyrin repeat domain 13b
chr16_-_20241304 0.32 ENSMUST00000040880.7
MAP6 domain containing 1
chr1_-_38129618 0.31 ENSMUST00000027251.6
REV1 homolog (S. cerevisiae)
chr5_-_124249758 0.31 ENSMUST00000162812.1
phosphatidylinositol transfer protein, membrane-associated 2
chr6_+_29272488 0.30 ENSMUST00000115289.1
ENSMUST00000054445.8
hypoxia inducible lipid droplet associated
chr4_+_150237211 0.29 ENSMUST00000133839.1
enolase 1, alpha non-neuron
chr18_+_35553401 0.29 ENSMUST00000181664.1
small nucleolar RNA host gene 4 (non-protein coding)
chr6_-_99726392 0.28 ENSMUST00000032152.8
ENSMUST00000101120.4
ENSMUST00000008273.6
prokineticin 2
chr14_-_18894255 0.28 ENSMUST00000124353.1
ubiquitin-conjugating enzyme E2E 2
chr19_+_18713225 0.28 ENSMUST00000055792.7
RIKEN cDNA D030056L22 gene
chr1_-_55088024 0.27 ENSMUST00000027123.8
heat shock protein 1 (chaperonin)
chr4_-_129600642 0.27 ENSMUST00000102593.4
eukaryotic translation initiation factor 3, subunit I
chr6_-_125165707 0.27 ENSMUST00000118875.1
glyceraldehyde-3-phosphate dehydrogenase
chr19_-_6921753 0.27 ENSMUST00000173635.1
estrogen related receptor, alpha
chr14_-_31830402 0.26 ENSMUST00000014640.7
ankyrin repeat domain 28
chr6_-_125165576 0.25 ENSMUST00000183272.1
ENSMUST00000182052.1
ENSMUST00000182277.1
glyceraldehyde-3-phosphate dehydrogenase
chr1_-_17097839 0.24 ENSMUST00000038382.4
junctophilin 1
chr13_-_112652295 0.24 ENSMUST00000099166.2
ENSMUST00000075748.5
DEAD (Asp-Glu-Ala-Asp) box polypeptide 4
chr14_-_89898466 0.24 ENSMUST00000081204.4
predicted gene 10110
chr2_-_32083783 0.24 ENSMUST00000056406.6
family with sequence similarity 78, member A
chr14_-_18893749 0.23 ENSMUST00000150727.1
ubiquitin-conjugating enzyme E2E 2
chr10_+_128238034 0.23 ENSMUST00000105245.2
timeless circadian clock 1
chr11_-_87359011 0.23 ENSMUST00000055438.4
protein phosphatase 1E (PP2C domain containing)
chr1_+_63176818 0.23 ENSMUST00000129339.1
eukaryotic translation elongation factor 1 beta 2
chr14_-_18893623 0.22 ENSMUST00000177259.1
ubiquitin-conjugating enzyme E2E 2
chr15_+_44787746 0.22 ENSMUST00000181839.1
RIKEN cDNA 2310069G16 gene
chr7_+_3704025 0.22 ENSMUST00000108623.1
ENSMUST00000139818.1
ENSMUST00000108625.1
ribosomal protein S9
chr11_+_84880308 0.22 ENSMUST00000020837.6
myosin XIX
chr7_+_112225856 0.22 ENSMUST00000050149.5
ENSMUST00000106647.1
ENSMUST00000106648.1
microtubule associated monooxygenase, calponin and LIM domain containing 2
chr9_-_35116804 0.22 ENSMUST00000034537.6
ST3 beta-galactoside alpha-2,3-sialyltransferase 4
chr1_+_16665189 0.21 ENSMUST00000177501.1
ENSMUST00000065373.5
transmembrane protein 70
chr3_+_94954075 0.21 ENSMUST00000107260.2
ENSMUST00000142311.1
ENSMUST00000137088.1
ENSMUST00000152869.1
ENSMUST00000107254.1
ENSMUST00000107253.1
regulatory factor X, 5 (influences HLA class II expression)
chr12_+_51348019 0.20 ENSMUST00000054308.6
G2/M-phase specific E3 ubiquitin ligase
chr2_+_68861564 0.20 ENSMUST00000176018.1
ceramide synthase 6
chrX_+_136741821 0.20 ENSMUST00000089350.4
cDNA sequence BC065397
chr6_+_85451488 0.19 ENSMUST00000032078.6
chaperonin containing Tcp1, subunit 7 (eta)
chr14_-_18893376 0.19 ENSMUST00000151926.1
ubiquitin-conjugating enzyme E2E 2
chr8_-_106893581 0.19 ENSMUST00000176437.1
ENSMUST00000177068.1
ENSMUST00000169312.1
ENSMUST00000176515.1
CTF8, chromosome transmission fidelity factor 8
chr2_+_69897255 0.18 ENSMUST00000131553.1
ubiquitin protein ligase E3 component n-recognin 3
chr8_-_106893515 0.18 ENSMUST00000176090.1
CTF8, chromosome transmission fidelity factor 8
chr6_-_38254009 0.17 ENSMUST00000169256.1
RIKEN cDNA D630045J12 gene
chr7_-_105736781 0.17 ENSMUST00000033179.6
ribosomal RNA processing 8, methyltransferase, homolog (yeast)
chr18_+_52465676 0.17 ENSMUST00000025406.7
serum response factor binding protein 1
chr5_-_149051604 0.16 ENSMUST00000093196.4
high mobility group box 1
chr11_-_84880195 0.15 ENSMUST00000067058.2
ENSMUST00000108080.2
phosphatidylinositol glycan anchor biosynthesis, class W
chr12_+_32820304 0.15 ENSMUST00000020886.7
nicotinamide phosphoribosyltransferase
chr11_-_115491796 0.14 ENSMUST00000106530.1
ENSMUST00000021082.6
5',3'-nucleotidase, cytosolic
chr5_+_129020069 0.14 ENSMUST00000031383.7
ENSMUST00000111343.1
RAN, member RAS oncogene family
chr19_-_44069736 0.14 ENSMUST00000172041.1
ENSMUST00000071698.6
ENSMUST00000112028.3
ER lipid raft associated 1
chr14_-_33447142 0.14 ENSMUST00000111944.3
ENSMUST00000022504.5
ENSMUST00000111945.2
mitogen-activated protein kinase 8
chr14_-_7174533 0.14 ENSMUST00000172431.1
predicted gene 3512
chr17_-_56626872 0.14 ENSMUST00000047226.8
lon peptidase 1, mitochondrial
chr13_+_118714678 0.13 ENSMUST00000022246.8
fibroblast growth factor 10
chr17_-_23677432 0.13 ENSMUST00000167059.1
ENSMUST00000024698.8
tumor necrosis factor receptor superfamily, member 12a
chr10_+_122678764 0.13 ENSMUST00000161487.1
ENSMUST00000067918.5
protein phosphatase 1H (PP2C domain containing)
chr17_-_45573253 0.13 ENSMUST00000165127.1
ENSMUST00000166469.1
ENSMUST00000024739.7
heat shock protein 90 alpha (cytosolic), class B member 1
chr19_-_44069526 0.13 ENSMUST00000170801.1
ER lipid raft associated 1
chr7_+_98703091 0.13 ENSMUST00000033009.9
protein-kinase, interferon-inducible double stranded RNA dependent inhibitor, repressor of (P58 repressor)
chr7_-_30973367 0.13 ENSMUST00000108116.3
lipolysis stimulated lipoprotein receptor
chr6_+_49073795 0.12 ENSMUST00000128616.1
ENSMUST00000031839.6
ENSMUST00000114500.1
mitochondrial assembly of ribosomal large subunit 1
chr1_+_9545397 0.12 ENSMUST00000072079.7
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
chr10_+_80755196 0.12 ENSMUST00000105336.2
DOT1-like, histone H3 methyltransferase (S. cerevisiae)
chr11_+_68691906 0.12 ENSMUST00000102611.3
myosin, heavy polypeptide 10, non-muscle
chr1_-_86388162 0.11 ENSMUST00000027440.3
neuromedin U receptor 1
chr7_-_30973399 0.11 ENSMUST00000098553.4
ENSMUST00000147431.1
lipolysis stimulated lipoprotein receptor
chr14_-_45318556 0.11 ENSMUST00000022378.7
ERO1-like (S. cerevisiae)
chr11_+_68692097 0.11 ENSMUST00000018887.8
myosin, heavy polypeptide 10, non-muscle
chr19_-_45006385 0.11 ENSMUST00000097715.2
mitochondrial ribosomal protein L43
chr8_+_83997613 0.11 ENSMUST00000095228.3
sterile alpha motif domain containing 1
chrX_-_93832106 0.10 ENSMUST00000045748.6
pyruvate dehydrogenase kinase, isoenzyme 3
chr15_-_75909543 0.10 ENSMUST00000123712.1
ENSMUST00000141475.1
ENSMUST00000144614.1
eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
chr16_+_20673517 0.10 ENSMUST00000115460.1
eukaryotic translation initiation factor 4, gamma 1
chr16_+_20498817 0.10 ENSMUST00000003320.6
eukaryotic translation initiation factor 2B, subunit 5 epsilon
chr11_+_68692070 0.10 ENSMUST00000108673.1
myosin, heavy polypeptide 10, non-muscle
chr13_+_90923122 0.10 ENSMUST00000051955.7
ribosomal protein S23
chr9_-_110654161 0.10 ENSMUST00000133191.1
ENSMUST00000167320.1
neurobeachin-like 2
chr5_-_149051300 0.09 ENSMUST00000110505.1
high mobility group box 1
chr7_+_89980749 0.09 ENSMUST00000181784.1
predicted gene, 26529
chr13_+_55635002 0.09 ENSMUST00000172272.1
ENSMUST00000099479.3
DEAD (Asp-Glu-Ala-Asp) box polypeptide 46
chr10_-_85102487 0.09 ENSMUST00000059383.6
four and a half LIM domains 4
chr4_+_116877376 0.09 ENSMUST00000044823.3
zinc finger SWIM-type containing 5
chr15_-_75909319 0.09 ENSMUST00000089680.3
ENSMUST00000141268.1
ENSMUST00000023235.6
ENSMUST00000109972.2
ENSMUST00000089681.5
ENSMUST00000109975.3
ENSMUST00000154584.1
eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
chr4_+_135152496 0.09 ENSMUST00000119564.1
runt related transcription factor 3
chr10_+_75893398 0.09 ENSMUST00000009236.4
Der1-like domain family, member 3
chr13_-_93499803 0.08 ENSMUST00000065537.7
junction-mediating and regulatory protein
chr4_-_133967953 0.08 ENSMUST00000102553.4
high mobility group nucleosomal binding domain 2
chr2_+_153492790 0.08 ENSMUST00000109783.1
RIKEN cDNA 4930404H24 gene
chr15_-_75909289 0.08 ENSMUST00000145764.1
ENSMUST00000116440.2
ENSMUST00000151066.1
eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
chr11_+_87127267 0.08 ENSMUST00000139532.1
tripartite motif-containing 37
chr5_+_52190650 0.08 ENSMUST00000180601.1
RIKEN cDNA 9230114K14 gene
chr11_+_121259983 0.08 ENSMUST00000106113.1
forkhead box K2
chr18_+_65581704 0.08 ENSMUST00000182979.1
zinc finger protein 532
chr11_+_97315716 0.08 ENSMUST00000019026.3
ENSMUST00000132168.1
mitochondrial ribosomal protein L45
chr6_-_85451248 0.07 ENSMUST00000113770.1
ENSMUST00000032080.2
protease-associated domain containing 1
chr2_+_27515157 0.07 ENSMUST00000113952.3
WD repeat domain 5
chr3_+_122245557 0.07 ENSMUST00000029769.7
glutamate-cysteine ligase, modifier subunit
chr5_+_146948640 0.07 ENSMUST00000146511.1
ENSMUST00000132102.1
general transcription factor III A
chr2_+_155517948 0.07 ENSMUST00000029135.8
ENSMUST00000065973.2
ENSMUST00000103142.5
acyl-CoA synthetase short-chain family member 2
chr3_-_9004686 0.06 ENSMUST00000120143.1
tumor protein D52
chrX_+_143518671 0.06 ENSMUST00000134402.1
p21 protein (Cdc42/Rac)-activated kinase 3
chr10_-_80387642 0.06 ENSMUST00000062946.6
ENSMUST00000105350.1
mex3 homolog D (C. elegans)
chr10_+_95940663 0.06 ENSMUST00000053484.6
early endosome antigen 1
chr4_-_34882919 0.06 ENSMUST00000098163.2
ENSMUST00000047950.5
zinc finger protein 292
chr2_+_91526756 0.06 ENSMUST00000111338.3
cytoskeleton associated protein 5
chr5_-_135064063 0.06 ENSMUST00000111205.1
ENSMUST00000141309.1
Williams Beuren syndrome chromosome region 22
chr18_+_64340225 0.06 ENSMUST00000175965.2
ENSMUST00000115145.3
one cut domain, family member 2
chr11_+_87127052 0.06 ENSMUST00000041282.6
tripartite motif-containing 37
chr8_-_122551316 0.06 ENSMUST00000067252.7
piezo-type mechanosensitive ion channel component 1
chr8_+_111094630 0.05 ENSMUST00000135302.1
ENSMUST00000039333.3
pyruvate dehydrogenase phosphatase regulatory subunit
chr14_+_31019183 0.05 ENSMUST00000052239.5
polybromo 1
chr10_-_79766872 0.05 ENSMUST00000047203.8
ring finger protein 126
chr8_+_104591464 0.05 ENSMUST00000059588.6
pyruvate dehyrogenase phosphatase catalytic subunit 2
chr3_-_9004472 0.05 ENSMUST00000091355.5
ENSMUST00000134788.1
tumor protein D52
chr2_+_27886416 0.05 ENSMUST00000028280.7
collagen, type V, alpha 1
chr7_+_141228766 0.05 ENSMUST00000106027.2
PHD and ring finger domains 1
chr1_+_74771886 0.05 ENSMUST00000006716.6
wingless-related MMTV integration site 6
chr10_+_121739915 0.04 ENSMUST00000065600.7
ENSMUST00000136432.1
cDNA sequence BC048403
chrX_+_10717451 0.04 ENSMUST00000156321.1
Mid1 interacting protein 1 (gastrulation specific G12-like (zebrafish))
chrX_+_10717390 0.04 ENSMUST00000115524.1
ENSMUST00000008179.6
Mid1 interacting protein 1 (gastrulation specific G12-like (zebrafish))
chr16_+_20673264 0.04 ENSMUST00000154950.1
ENSMUST00000115461.1
eukaryotic translation initiation factor 4, gamma 1
chr10_+_67535493 0.04 ENSMUST00000145936.1
early growth response 2
chr15_-_39857459 0.04 ENSMUST00000022915.3
ENSMUST00000110306.1
dihydropyrimidinase
chr15_+_80287234 0.04 ENSMUST00000160424.1
calcium channel, voltage-dependent, alpha 1I subunit
chr3_+_122245625 0.04 ENSMUST00000178826.1
glutamate-cysteine ligase, modifier subunit
chr11_-_102819663 0.03 ENSMUST00000092567.4
gap junction protein, gamma 1
chr7_+_129257027 0.03 ENSMUST00000094018.4
phosphatidic acid phosphatase type 2 domain containing 1A
chr6_-_29212240 0.03 ENSMUST00000160878.1
ENSMUST00000078155.5
inosine 5'-phosphate dehydrogenase 1
chr11_-_120348475 0.03 ENSMUST00000062147.7
ENSMUST00000128055.1
actin, gamma, cytoplasmic 1
chr8_-_45999860 0.03 ENSMUST00000053558.9
ankyrin repeat domain 37
chr9_+_106203108 0.02 ENSMUST00000024047.5
twinfilin, actin-binding protein, homolog 2 (Drosophila)
chr3_+_103279293 0.02 ENSMUST00000029444.6
ENSMUST00000106860.1
tripartite motif-containing 33
chr11_-_104442232 0.02 ENSMUST00000106977.1
ENSMUST00000106972.1
KAT8 regulatory NSL complex subunit 1
chr2_+_69897220 0.02 ENSMUST00000055758.9
ENSMUST00000112251.2
ubiquitin protein ligase E3 component n-recognin 3
chr15_+_101174096 0.02 ENSMUST00000000544.9
activin A receptor, type 1B
chr15_+_86058727 0.02 ENSMUST00000138134.1
GRAM domain containing 4
chr14_-_20181773 0.02 ENSMUST00000024011.8
potassium channel, subfamily K, member 5
chr10_+_80226644 0.02 ENSMUST00000130260.1
melanoma associated antigen (mutated) 1
chr11_-_70687917 0.01 ENSMUST00000108545.2
ENSMUST00000120261.1
ENSMUST00000036299.7
ENSMUST00000119120.1
ENSMUST00000100933.3
calmodulin binding transcription activator 2
chr19_+_25610533 0.01 ENSMUST00000048935.4
doublesex and mab-3 related transcription factor 3
chr2_-_121140649 0.01 ENSMUST00000110674.2
leucine carboxyl methyltransferase 2
chr2_-_26237368 0.01 ENSMUST00000036187.8
quiescin Q6 sulfhydryl oxidase 2
chr15_+_102203639 0.01 ENSMUST00000118729.1
ENSMUST00000119168.1
ENSMUST00000141465.1
ENSMUST00000139960.1
zinc finger protein 740
chr10_-_13193096 0.00 ENSMUST00000019950.4
LTV1 homolog (S. cerevisiae)
chr14_+_31019159 0.00 ENSMUST00000112094.1
ENSMUST00000144009.1
polybromo 1
chr10_+_36974558 0.00 ENSMUST00000105510.1
histone deacetylase 2

Network of associatons between targets according to the STRING database.

First level regulatory network of Hif1a

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:1990523 bone regeneration(GO:1990523)
0.2 0.7 GO:0002842 positive regulation of T cell mediated immune response to tumor cell(GO:0002842) protein import into mitochondrial intermembrane space(GO:0045041)
0.2 0.7 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.2 0.5 GO:0033693 neurofilament bundle assembly(GO:0033693)
0.1 0.8 GO:0001844 protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:0001844)
0.1 0.5 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.1 0.5 GO:0060025 regulation of synaptic activity(GO:0060025)
0.1 0.9 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.1 0.5 GO:0015886 heme transport(GO:0015886)
0.1 0.3 GO:0070650 actin filament bundle distribution(GO:0070650)
0.1 0.4 GO:0018201 peptidyl-glycine modification(GO:0018201)
0.1 0.5 GO:2000622 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.1 0.3 GO:0060983 epicardium-derived cardiac vascular smooth muscle cell differentiation(GO:0060983)
0.1 0.3 GO:0045819 plasmacytoid dendritic cell activation(GO:0002270) positive regulation of glycogen catabolic process(GO:0045819)
0.1 0.2 GO:1904274 tricellular tight junction assembly(GO:1904274)
0.1 0.2 GO:1904975 response to bleomycin(GO:1904975) cellular response to bleomycin(GO:1904976)
0.1 0.2 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.1 0.1 GO:2000017 positive regulation of determination of dorsal identity(GO:2000017)
0.1 0.5 GO:0035356 cellular triglyceride homeostasis(GO:0035356)
0.1 0.3 GO:0006498 N-terminal protein lipidation(GO:0006498)
0.1 0.4 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.1 0.2 GO:0045903 positive regulation of translational fidelity(GO:0045903)
0.1 0.3 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.1 0.6 GO:0071372 cellular response to follicle-stimulating hormone stimulus(GO:0071372)
0.1 0.2 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.0 0.1 GO:0061033 bronchiole development(GO:0060435) secretion by lung epithelial cell involved in lung growth(GO:0061033) white fat cell proliferation(GO:0070343) regulation of white fat cell proliferation(GO:0070350) positive regulation of hair follicle cell proliferation(GO:0071338)
0.0 0.1 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.0 0.2 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.0 0.1 GO:1903659 transforming growth factor beta activation(GO:0036363) regulation of complement-dependent cytotoxicity(GO:1903659) negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.0 0.4 GO:0070475 rRNA base methylation(GO:0070475)
0.0 0.1 GO:0090071 negative regulation of ribosome biogenesis(GO:0090071)
0.0 0.4 GO:1900264 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.0 0.6 GO:1904816 positive regulation of protein localization to chromosome, telomeric region(GO:1904816)
0.0 0.1 GO:0006244 pyrimidine nucleotide catabolic process(GO:0006244) pyrimidine deoxyribonucleotide catabolic process(GO:0009223)
0.0 0.5 GO:0045820 negative regulation of glycolytic process(GO:0045820)
0.0 0.3 GO:0045541 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.0 0.3 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055)
0.0 1.1 GO:0001706 endoderm formation(GO:0001706)
0.0 0.1 GO:0034729 histone H3-K79 methylation(GO:0034729)
0.0 0.3 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.1 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.0 0.1 GO:0070889 platelet alpha granule organization(GO:0070889)
0.0 0.8 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.2 GO:0046015 regulation of transcription by glucose(GO:0046015)
0.0 0.1 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.0 0.4 GO:0030953 astral microtubule organization(GO:0030953)
0.0 0.1 GO:0022417 protein maturation by protein folding(GO:0022417)
0.0 0.1 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.0 0.2 GO:0007141 male meiosis I(GO:0007141)
0.0 0.0 GO:0070172 positive regulation of tooth mineralization(GO:0070172)
0.0 0.1 GO:2000507 positive regulation of energy homeostasis(GO:2000507)
0.0 0.2 GO:0099515 actin filament-based transport(GO:0099515)
0.0 0.2 GO:0009435 NAD biosynthetic process(GO:0009435)
0.0 0.0 GO:0019859 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.0 0.1 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.0 0.1 GO:0051409 response to nitrosative stress(GO:0051409)
0.0 0.4 GO:0009299 mRNA transcription(GO:0009299)
0.0 0.1 GO:0051790 acetate metabolic process(GO:0006083) short-chain fatty acid biosynthetic process(GO:0051790)
0.0 1.2 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.3 GO:0010884 positive regulation of lipid storage(GO:0010884)
0.0 0.1 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.1 1.0 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.1 0.3 GO:0097135 cyclin E2-CDK2 complex(GO:0097135)
0.1 0.7 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.1 0.5 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.1 0.5 GO:0097452 GAIT complex(GO:0097452)
0.1 0.6 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.1 0.3 GO:0097513 myosin II filament(GO:0097513)
0.0 0.2 GO:0071547 piP-body(GO:0071547)
0.0 0.1 GO:0031074 nucleocytoplasmic shuttling complex(GO:0031074)
0.0 0.5 GO:0005883 neurofilament(GO:0005883)
0.0 1.0 GO:0031527 filopodium membrane(GO:0031527)
0.0 0.4 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.0 1.4 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.1 GO:0017109 glutamate-cysteine ligase complex(GO:0017109)
0.0 0.2 GO:0033553 rDNA heterochromatin(GO:0033553)
0.0 0.2 GO:0030314 junctional membrane complex(GO:0030314)
0.0 0.2 GO:0061689 tricellular tight junction(GO:0061689)
0.0 0.1 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 0.4 GO:0046930 pore complex(GO:0046930)
0.0 0.5 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.1 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.0 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.2 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 0.1 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.0 0.1 GO:0044308 axonal spine(GO:0044308)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.2 0.5 GO:0035605 peptidyl-cysteine S-nitrosylase activity(GO:0035605)
0.2 0.5 GO:0050252 2-acylglycerol O-acyltransferase activity(GO:0003846) retinol O-fatty-acyltransferase activity(GO:0050252)
0.2 0.9 GO:0042296 ISG15 transferase activity(GO:0042296)
0.1 0.4 GO:0009383 rRNA (cytosine-C5-)-methyltransferase activity(GO:0009383)
0.1 0.7 GO:0034186 apolipoprotein A-I binding(GO:0034186)
0.1 0.5 GO:0015232 heme transporter activity(GO:0015232)
0.1 1.0 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 0.4 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.1 0.3 GO:0000401 open form four-way junction DNA binding(GO:0000401) crossed form four-way junction DNA binding(GO:0000402)
0.1 1.2 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 0.6 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.1 0.5 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1 0.2 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836) monosialoganglioside sialyltransferase activity(GO:0047288)
0.0 1.0 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 1.4 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.0 0.4 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.2 GO:1990932 5.8S rRNA binding(GO:1990932)
0.0 0.2 GO:0032027 myosin light chain binding(GO:0032027)
0.0 0.1 GO:0004357 glutamate-cysteine ligase activity(GO:0004357)
0.0 0.1 GO:0004705 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.1 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.0 0.4 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.5 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.1 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.0 0.1 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.0 0.1 GO:0070883 pre-miRNA binding(GO:0070883)
0.0 0.1 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.0 0.1 GO:0002135 CTP binding(GO:0002135)
0.0 0.5 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.5 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.2 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.3 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.4 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.2 GO:0008097 5S rRNA binding(GO:0008097)
0.0 0.1 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.1 GO:0019103 pyrimidine nucleotide binding(GO:0019103)
0.0 0.1 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.2 GO:0030169 low-density lipoprotein particle binding(GO:0030169)
0.0 0.7 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.1 GO:0046972 histone acetyltransferase activity (H4-K5 specific)(GO:0043995) histone acetyltransferase activity (H4-K8 specific)(GO:0043996) histone acetyltransferase activity (H4-K16 specific)(GO:0046972)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.0 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 1.0 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.3 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.5 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.6 PID AURORA A PATHWAY Aurora A signaling
0.0 1.3 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.5 PID EPHA FWDPATHWAY EPHA forward signaling
0.0 0.1 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 1.5 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 1.6 REACTOME ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S Genes involved in Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
0.0 0.3 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.7 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 0.3 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.7 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.5 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.1 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.1 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.1 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.3 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse