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2D miR_HR1_12

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Results for Lef1

Z-value: 0.92

Motif logo

Transcription factors associated with Lef1

Gene Symbol Gene ID Gene Info
ENSMUSG00000027985.8 lymphoid enhancer binding factor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Lef1mm10_v2_chr3_+_131112785_1311128030.746.2e-03Click!

Activity profile of Lef1 motif

Sorted Z-values of Lef1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr5_-_148392810 3.65 ENSMUST00000138257.1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr6_-_148944750 2.14 ENSMUST00000111562.1
ENSMUST00000081956.5
family with sequence similarity 60, member A
chr16_-_4559720 1.62 ENSMUST00000005862.7
transcription factor AP4
chr5_+_110330697 1.54 ENSMUST00000112481.1
polymerase (DNA directed), epsilon
chr4_-_91376433 1.49 ENSMUST00000107109.2
ENSMUST00000107111.2
ENSMUST00000107120.1
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr11_-_102925086 1.48 ENSMUST00000021311.9
kinesin family member 18B
chr14_+_46760526 1.21 ENSMUST00000067426.4
cyclin-dependent kinase inhibitor 3
chr12_-_76795489 1.17 ENSMUST00000082431.3
glutathione peroxidase 2
chr18_+_34625009 1.13 ENSMUST00000166044.1
kinesin family member 20A
chr2_-_65567505 1.09 ENSMUST00000100069.2
sodium channel, voltage-gated, type III, alpha
chr1_+_158362261 1.07 ENSMUST00000046110.9
astrotactin 1
chr5_-_138171248 1.06 ENSMUST00000153867.1
minichromosome maintenance deficient 7 (S. cerevisiae)
chr14_-_98169542 1.03 ENSMUST00000069334.7
ENSMUST00000071533.6
dachshund 1 (Drosophila)
chr4_+_107367757 1.03 ENSMUST00000139560.1
NDC1 transmembrane nucleoporin
chr18_+_34624621 1.00 ENSMUST00000167161.1
kinesin family member 20A
chr2_-_65567465 1.00 ENSMUST00000066432.5
sodium channel, voltage-gated, type III, alpha
chr4_-_91376490 0.99 ENSMUST00000107124.3
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr1_+_135232045 0.95 ENSMUST00000110798.3
predicted gene 4204
chr5_-_138170992 0.94 ENSMUST00000139983.1
minichromosome maintenance deficient 7 (S. cerevisiae)
chr7_-_109170308 0.94 ENSMUST00000036992.7
LIM domain only 1
chr14_+_101840501 0.89 ENSMUST00000159026.1
LIM domain only 7
chr5_+_120649188 0.87 ENSMUST00000156722.1
RAS protein activator like 1 (GAP1 like)
chr1_+_180641330 0.86 ENSMUST00000085804.5
lin-9 homolog (C. elegans)
chr17_-_70851189 0.81 ENSMUST00000059775.8
TGFB-induced factor homeobox 1
chr18_+_11633276 0.78 ENSMUST00000115861.2
retinoblastoma binding protein 8
chr12_-_54986328 0.78 ENSMUST00000038926.6
bromodomain adjacent to zinc finger domain 1A
chr13_-_103096818 0.78 ENSMUST00000166336.1
microtubule associated serine/threonine kinase family member 4
chr1_+_158362330 0.76 ENSMUST00000170718.1
astrotactin 1
chr6_-_124813065 0.75 ENSMUST00000149610.2
triosephosphate isomerase 1
chr2_-_172370506 0.74 ENSMUST00000109139.1
ENSMUST00000028997.7
ENSMUST00000109140.3
aurora kinase A
chr10_-_5805412 0.73 ENSMUST00000019907.7
F-box protein 5
chr17_+_8182247 0.72 ENSMUST00000161898.1
Fgfr1 oncogene partner
chr9_+_44084944 0.71 ENSMUST00000176416.1
ENSMUST00000065461.7
ubiquitin specific peptidase 2
chr2_+_153031852 0.70 ENSMUST00000037235.6
X Kell blood group precursor related family member 7 homolog
chrX_+_71556874 0.70 ENSMUST00000123100.1
high mobility group box 3
chr12_-_54986363 0.69 ENSMUST00000173433.1
ENSMUST00000173803.1
bromodomain adjacent to zinc finger domain 1A
predicted gene 20403
chrX_-_48034842 0.69 ENSMUST00000039026.7
apelin
chr2_+_157560078 0.69 ENSMUST00000153739.2
ENSMUST00000173595.1
ENSMUST00000109526.1
ENSMUST00000173839.1
ENSMUST00000173041.1
ENSMUST00000173793.1
ENSMUST00000172487.1
ENSMUST00000088484.5
neuronatin
chr2_-_80129458 0.67 ENSMUST00000102653.1
phosphodiesterase 1A, calmodulin-dependent
chr1_+_6734827 0.66 ENSMUST00000139838.1
suppression of tumorigenicity 18
chr2_-_64975762 0.66 ENSMUST00000156765.1
growth factor receptor bound protein 14
chr7_-_78577771 0.66 ENSMUST00000039438.7
neurotrophic tyrosine kinase, receptor, type 3
chrX_+_73675500 0.63 ENSMUST00000171398.1
solute carrier family 6 (neurotransmitter transporter, creatine), member 8
chr9_-_16378231 0.63 ENSMUST00000082170.5
FAT tumor suppressor homolog 3 (Drosophila)
chr12_-_73113407 0.62 ENSMUST00000175693.1
sine oculis-related homeobox 4
chr2_+_55437100 0.61 ENSMUST00000112633.2
ENSMUST00000112632.1
potassium inwardly-rectifying channel, subfamily J, member 3
chr3_-_51560816 0.60 ENSMUST00000037141.7
SET domain containing (lysine methyltransferase) 7
chr9_-_71896047 0.59 ENSMUST00000184448.1
transcription factor 12
chr11_+_76243715 0.58 ENSMUST00000040577.4
RNA methyltransferase like 1
chr6_+_21985903 0.58 ENSMUST00000137437.1
ENSMUST00000115383.2
cadherin-like and PC-esterase domain containing 1
chr1_+_59482133 0.57 ENSMUST00000114246.2
ENSMUST00000037105.6
frizzled homolog 7 (Drosophila)
chr1_-_12991109 0.57 ENSMUST00000115403.2
ENSMUST00000115402.1
solute carrier organic anion transporter family, member 5A1
chr4_+_108479081 0.56 ENSMUST00000155068.1
zinc finger, CCHC domain containing 11
chr9_+_51213683 0.55 ENSMUST00000034554.7
POU domain, class 2, associating factor 1
chr18_+_4921662 0.54 ENSMUST00000143254.1
supervillin
chr11_-_88863717 0.54 ENSMUST00000107904.2
A kinase (PRKA) anchor protein 1
chr5_+_31251678 0.54 ENSMUST00000054829.7
ENSMUST00000114570.1
ENSMUST00000075611.7
keratinocyte associated protein 3
chr1_+_187997835 0.54 ENSMUST00000110938.1
estrogen-related receptor gamma
chr1_+_187997821 0.52 ENSMUST00000027906.6
estrogen-related receptor gamma
chr2_+_121357714 0.52 ENSMUST00000125812.1
ENSMUST00000078222.2
ENSMUST00000125221.1
ENSMUST00000150271.1
creatine kinase, mitochondrial 1, ubiquitous
chr13_+_16014457 0.52 ENSMUST00000164993.1
inhibin beta-A
chr11_-_77489666 0.51 ENSMUST00000037593.7
ENSMUST00000092892.3
ankyrin repeat domain 13b
chr10_-_18743691 0.51 ENSMUST00000019999.5
DNA segment, Chr 10, Brigham & Women's Genetics 1379 expressed
chr11_+_79660532 0.51 ENSMUST00000155381.1
RAB11 family interacting protein 4 (class II)
chr6_-_121003099 0.51 ENSMUST00000098457.2
ENSMUST00000150503.1
microtubule associated monooxygenase, calponin and LIM domain containing 3
chr2_+_181767040 0.50 ENSMUST00000108756.1
myelin transcription factor 1
chr9_+_110132015 0.50 ENSMUST00000088716.5
ENSMUST00000111969.1
ENSMUST00000035057.7
ENSMUST00000111966.1
ENSMUST00000111968.1
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1
chr11_-_97629685 0.50 ENSMUST00000052281.4
RIKEN cDNA E130012A19 gene
chr8_-_84773381 0.49 ENSMUST00000109764.1
nuclear factor I/X
chr2_+_181767283 0.49 ENSMUST00000108757.2
myelin transcription factor 1
chr5_+_108065696 0.49 ENSMUST00000172045.1
metal response element binding transcription factor 2
chr1_-_165934900 0.47 ENSMUST00000069609.5
ENSMUST00000111427.2
ENSMUST00000111426.4
POU domain, class 2, transcription factor 1
chr17_+_47630690 0.47 ENSMUST00000024779.8
ubiquitin specific peptidase 49
chr9_+_119402444 0.46 ENSMUST00000035093.8
ENSMUST00000165044.1
activin receptor IIB
chr6_+_54039558 0.46 ENSMUST00000046856.7
chimerin (chimaerin) 2
chr6_-_99096196 0.45 ENSMUST00000175886.1
forkhead box P1
chr11_-_49712674 0.45 ENSMUST00000020624.6
ENSMUST00000145353.1
CCR4-NOT transcription complex, subunit 6
chr5_-_21785115 0.45 ENSMUST00000115193.1
ENSMUST00000115192.1
ENSMUST00000115195.1
ENSMUST00000030771.5
DnaJ (Hsp40) homolog, subfamily C, member 2
chr5_+_37242025 0.44 ENSMUST00000114158.2
collapsin response mediator protein 1
chr2_+_31950257 0.43 ENSMUST00000001920.7
allograft inflammatory factor 1-like
chr17_+_26414820 0.43 ENSMUST00000182897.1
ENSMUST00000183077.1
ENSMUST00000053020.7
neuralized homolog 1b (Drosophila)
chr15_-_78405824 0.43 ENSMUST00000058659.7
thiosulfate sulfurtransferase, mitochondrial
chr5_-_48889531 0.42 ENSMUST00000176978.1
Kv channel interacting protein 4
chr7_+_100493795 0.42 ENSMUST00000129324.1
uncoupling protein 2 (mitochondrial, proton carrier)
chr5_-_138171216 0.42 ENSMUST00000147920.1
minichromosome maintenance deficient 7 (S. cerevisiae)
chr2_+_30078213 0.41 ENSMUST00000150770.1
protein kinase N3
chr7_+_100494044 0.41 ENSMUST00000153287.1
uncoupling protein 2 (mitochondrial, proton carrier)
chr6_-_47594967 0.41 ENSMUST00000081721.6
ENSMUST00000114618.1
ENSMUST00000114616.1
enhancer of zeste homolog 2 (Drosophila)
chr16_-_89818338 0.41 ENSMUST00000164263.2
T cell lymphoma invasion and metastasis 1
chr19_-_37330613 0.40 ENSMUST00000131070.1
insulin degrading enzyme
chr2_+_138278481 0.40 ENSMUST00000075410.4
BTB (POZ) domain containing 3
chr6_+_21986438 0.40 ENSMUST00000115382.1
cadherin-like and PC-esterase domain containing 1
chr14_+_101840602 0.40 ENSMUST00000159314.1
LIM domain only 7
chr14_+_25607797 0.40 ENSMUST00000160229.1
zinc finger, MIZ-type containing 1
chr1_+_165788746 0.40 ENSMUST00000161559.2
CD247 antigen
chr3_+_88532314 0.39 ENSMUST00000172699.1
mex3 homolog A (C. elegans)
chr15_+_77084367 0.39 ENSMUST00000181870.1
RIKEN cDNA 1700109K24 gene
chr9_+_102506072 0.39 ENSMUST00000039390.4
kyphoscoliosis peptidase
chr15_-_81408261 0.38 ENSMUST00000057236.3
DnaJ (Hsp40) homolog, subfamily B, member 7
chr18_+_69593361 0.38 ENSMUST00000114978.2
ENSMUST00000114977.1
transcription factor 4
chr12_-_98737405 0.38 ENSMUST00000170188.1
protein tyrosine phosphatase, non-receptor type 21
chr4_+_127172866 0.38 ENSMUST00000106094.2
discs, large (Drosophila) homolog-associated protein 3
chr17_-_23835743 0.38 ENSMUST00000059906.6
protease, serine, 33
chr11_+_94044111 0.37 ENSMUST00000132079.1
sperm associated antigen 9
chr3_-_95882031 0.37 ENSMUST00000161994.1
predicted gene 129
chr3_-_27896360 0.37 ENSMUST00000058077.3
transmembrane protein 212
chr11_-_78497734 0.37 ENSMUST00000061174.6
sterile alpha and HEAT/Armadillo motif containing 1
chr2_+_74704615 0.36 ENSMUST00000151380.1
homeobox D8
chr3_+_86084434 0.35 ENSMUST00000107664.2
SH3 domain protein D19
chr7_-_78578308 0.35 ENSMUST00000039431.7
neurotrophic tyrosine kinase, receptor, type 3
chr8_-_40511298 0.35 ENSMUST00000149992.1
CCR4-NOT transcription complex, subunit 7
chr14_+_70457447 0.34 ENSMUST00000003561.3
phytanoyl-CoA hydroxylase interacting protein
chr11_-_88718078 0.34 ENSMUST00000092794.5
musashi RNA-binding protein 2
chr3_-_50443603 0.34 ENSMUST00000029297.4
solute carrier family 7 (cationic amino acid transporter, y+ system), member 11
chr1_-_67038824 0.34 ENSMUST00000119559.1
ENSMUST00000149996.1
ENSMUST00000027149.5
ENSMUST00000113979.3
LanC (bacterial lantibiotic synthetase component C)-like 1
chrX_-_57393020 0.33 ENSMUST00000143310.1
ENSMUST00000098470.2
ENSMUST00000114726.1
RNA binding motif protein, X chromosome
chr11_-_120598346 0.33 ENSMUST00000026125.2
Aly/REF export factor
chr2_-_27475600 0.33 ENSMUST00000147736.1
bromodomain containing 3
chr14_+_47663756 0.32 ENSMUST00000022391.7
kinectin 1
chr6_+_15185456 0.32 ENSMUST00000115472.1
ENSMUST00000115474.1
ENSMUST00000031545.7
ENSMUST00000137628.1
forkhead box P2
chr13_+_35741313 0.32 ENSMUST00000163595.2
chromodomain protein, Y chromosome-like
chr6_+_134035691 0.32 ENSMUST00000081028.6
ENSMUST00000111963.1
ets variant gene 6 (TEL oncogene)
chrX_-_143933089 0.31 ENSMUST00000087313.3
doublecortin
chrX_-_57392962 0.31 ENSMUST00000114730.1
RNA binding motif protein, X chromosome
chr14_+_101729907 0.31 ENSMUST00000100337.3
LIM domain only 7
chr13_-_104109576 0.31 ENSMUST00000109315.3
neurolysin (metallopeptidase M3 family)
chrX_+_151198078 0.30 ENSMUST00000184730.1
ENSMUST00000184392.1
ENSMUST00000096285.4
WNK lysine deficient protein kinase 3
chr15_-_98953541 0.30 ENSMUST00000097014.5
tubulin, alpha 1A
chr2_-_80128834 0.30 ENSMUST00000102654.4
ENSMUST00000102655.3
phosphodiesterase 1A, calmodulin-dependent
chr9_+_108826320 0.29 ENSMUST00000024238.5
cadherin, EGF LAG seven-pass G-type receptor 3 (flamingo homolog, Drosophila)
chr9_+_96259246 0.29 ENSMUST00000179065.1
ENSMUST00000165768.2
transcription factor Dp 2
chr4_+_13751297 0.29 ENSMUST00000105566.2
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr2_-_6884940 0.28 ENSMUST00000183091.1
ENSMUST00000182851.1
CUGBP, Elav-like family member 2
chr8_+_79028587 0.27 ENSMUST00000119254.1
zinc finger protein 827
chr8_-_40511663 0.27 ENSMUST00000135269.1
ENSMUST00000034012.3
CCR4-NOT transcription complex, subunit 7
chr3_-_86920830 0.27 ENSMUST00000029719.8
doublecortin-like kinase 2
chr15_-_8710409 0.27 ENSMUST00000157065.1
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr12_+_29528382 0.27 ENSMUST00000049784.9
myelin transcription factor 1-like
chr1_-_181183739 0.27 ENSMUST00000159290.1
WD repeat domain 26
chr11_-_78497458 0.26 ENSMUST00000108287.3
sterile alpha and HEAT/Armadillo motif containing 1
chr19_-_14598031 0.26 ENSMUST00000167776.2
transducin-like enhancer of split 4, homolog of Drosophila E(spl)
chr11_+_108920800 0.26 ENSMUST00000140821.1
axin2
chr5_+_148265202 0.26 ENSMUST00000110515.2
microtubule associated tumor suppressor candidate 2
chr19_-_4334001 0.26 ENSMUST00000176653.1
lysine (K)-specific demethylase 2A
chrX_+_109095359 0.25 ENSMUST00000033598.8
SH3-binding domain glutamic acid-rich protein like
chr11_-_52282564 0.25 ENSMUST00000086844.3
transcription factor 7, T cell specific
chr4_-_34882919 0.25 ENSMUST00000098163.2
ENSMUST00000047950.5
zinc finger protein 292
chr5_-_52190484 0.25 ENSMUST00000031061.7
DEAH (Asp-Glu-Ala-His) box polypeptide 15
chr16_-_5132458 0.25 ENSMUST00000035672.3
periplakin
chr4_+_117849193 0.25 ENSMUST00000132043.2
ENSMUST00000169990.1
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr5_+_148265307 0.25 ENSMUST00000110514.1
microtubule associated tumor suppressor candidate 2
chr2_-_148040196 0.25 ENSMUST00000136555.1
RIKEN cDNA 9030622O22 gene
chr8_-_85080652 0.24 ENSMUST00000152785.1
WD repeat domain containing 83
chr19_+_44992127 0.24 ENSMUST00000179305.1
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
chr12_+_84996309 0.24 ENSMUST00000168977.1
ENSMUST00000021670.8
YLP motif containing 1
chr3_-_127837419 0.24 ENSMUST00000051737.6
adaptor-related protein complex 1 associated regulatory protein
chr12_+_76072016 0.24 ENSMUST00000131480.1
spectrin repeat containing, nuclear envelope 2
chr1_+_60908993 0.24 ENSMUST00000027164.2
cytotoxic T-lymphocyte-associated protein 4
chr11_+_108921648 0.23 ENSMUST00000144511.1
axin2
chr5_+_150259922 0.23 ENSMUST00000087204.5
furry homolog (Drosophila)
chr9_-_110117303 0.23 ENSMUST00000136969.1
DEAH (Asp-Glu-Ala-His) box polypeptide 30
chr16_-_5013505 0.23 ENSMUST00000023191.10
ENSMUST00000090453.5
rogdi homolog (Drosophila)
chr14_-_31323884 0.23 ENSMUST00000048603.7
dynein, axonemal, heavy chain 1
chr2_-_73580288 0.23 ENSMUST00000028515.3
cholinergic receptor, nicotinic, alpha polypeptide 1 (muscle)
chr4_-_123664725 0.23 ENSMUST00000147030.1
microtubule-actin crosslinking factor 1
chr14_-_55106547 0.22 ENSMUST00000036041.8
adaptor protein complex AP-1, gamma 2 subunit
chr3_-_108210438 0.22 ENSMUST00000117784.1
ENSMUST00000119650.1
ENSMUST00000117409.1
ataxin 7-like 2
chr1_+_161142706 0.22 ENSMUST00000111608.1
ENSMUST00000052245.8
ankyrin repeat domain 45
chr6_-_86733218 0.22 ENSMUST00000113679.1
germ cell-less homolog 1 (Drosophila)
chr12_+_80518990 0.22 ENSMUST00000021558.6
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 16
chr12_+_76370266 0.22 ENSMUST00000042779.3
zinc finger and BTB domain containing 1
chr15_-_50882806 0.22 ENSMUST00000184885.1
trichorhinophalangeal syndrome I (human)
chr1_+_165788681 0.21 ENSMUST00000161971.1
ENSMUST00000178336.1
ENSMUST00000005907.5
ENSMUST00000027849.4
CD247 antigen
chr12_+_71048338 0.21 ENSMUST00000135709.1
AT rich interactive domain 4A (RBP1-like)
chr6_-_52218686 0.21 ENSMUST00000134367.2
homeobox A7
chr9_-_49798905 0.21 ENSMUST00000114476.2
neural cell adhesion molecule 1
chr15_-_8710734 0.21 ENSMUST00000005493.7
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr2_-_6721890 0.21 ENSMUST00000114927.2
CUGBP, Elav-like family member 2
chr9_-_59486323 0.21 ENSMUST00000165322.1
ariadne ubiquitin-conjugating enzyme E2 binding protein homolog 1 (Drosophila)
chr11_-_42000284 0.21 ENSMUST00000109292.2
ENSMUST00000109290.1
gamma-aminobutyric acid (GABA) A receptor, subunit gamma 2
chr1_+_87183310 0.21 ENSMUST00000044533.8
protease, serine 56
chr1_-_183147461 0.21 ENSMUST00000171366.1
dispatched homolog 1 (Drosophila)
chr16_-_56024628 0.21 ENSMUST00000119981.1
ENSMUST00000096021.3
PEST proteolytic signal containing nuclear protein
chr5_+_86071734 0.20 ENSMUST00000031171.7
signal transducing adaptor family member 1
chr5_+_108461222 0.20 ENSMUST00000046975.5
ENSMUST00000112597.1
polycomb group ring finger 3
chr5_+_65131184 0.20 ENSMUST00000031089.5
ENSMUST00000101191.3
kelch-like 5
chr9_+_35267857 0.20 ENSMUST00000034543.4
RNA pseudouridylate synthase domain containing 4
chr19_-_46338632 0.20 ENSMUST00000051234.8
ENSMUST00000167861.1
CUE domain containing 2
chrX_+_169879596 0.20 ENSMUST00000112105.1
ENSMUST00000078947.5
midline 1
chr14_+_69029289 0.20 ENSMUST00000014957.8
stanniocalcin 1
chr9_-_65021645 0.20 ENSMUST00000036615.5
protein tyrosine phosphatase-like A domain containing 1
chr2_-_6721606 0.20 ENSMUST00000150624.2
ENSMUST00000142941.1
ENSMUST00000100429.4
ENSMUST00000182879.1
CUGBP, Elav-like family member 2
chr16_+_20097554 0.19 ENSMUST00000023509.3
kelch-like 24
chr18_-_43059418 0.19 ENSMUST00000025377.7
protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), beta isoform
chr12_+_84996487 0.19 ENSMUST00000101202.3
YLP motif containing 1
chr15_-_50889691 0.19 ENSMUST00000165201.2
ENSMUST00000184458.1
trichorhinophalangeal syndrome I (human)
chr8_-_60954726 0.19 ENSMUST00000110302.1
chloride channel 3
chr16_+_78930940 0.19 ENSMUST00000114216.1
ENSMUST00000069148.6
ENSMUST00000023568.7
chondrolectin
chr3_-_122619442 0.19 ENSMUST00000162947.1
formin binding protein 1-like
chr2_+_84826997 0.18 ENSMUST00000028470.3
translocase of inner mitochondrial membrane 10

Network of associatons between targets according to the STRING database.

First level regulatory network of Lef1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0045004 DNA replication proofreading(GO:0045004)
0.4 1.5 GO:0007056 spindle assembly involved in female meiosis(GO:0007056)
0.3 1.7 GO:0046684 response to pyrethroid(GO:0046684)
0.3 1.0 GO:0048691 positive regulation of sprouting of injured axon(GO:0048687) positive regulation of axon extension involved in regeneration(GO:0048691)
0.2 0.7 GO:0046166 alditol catabolic process(GO:0019405) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.2 2.4 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.2 0.7 GO:0051466 corticotropin-releasing hormone secretion(GO:0043396) regulation of corticotropin-releasing hormone secretion(GO:0043397) positive regulation of corticotropin-releasing hormone secretion(GO:0051466)
0.2 3.7 GO:0015809 arginine transport(GO:0015809)
0.2 0.7 GO:1903537 meiotic cell cycle process involved in oocyte maturation(GO:1903537) regulation of meiotic cell cycle process involved in oocyte maturation(GO:1903538)
0.2 0.6 GO:0015881 creatine transport(GO:0015881)
0.2 1.0 GO:0060244 negative regulation of cell proliferation involved in contact inhibition(GO:0060244)
0.2 2.3 GO:2001269 positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269)
0.2 0.9 GO:0098528 skeletal muscle fiber differentiation(GO:0098528)
0.2 0.8 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.1 0.6 GO:2000383 regulation of ectoderm development(GO:2000383) negative regulation of ectoderm development(GO:2000384)
0.1 0.4 GO:0035928 rRNA import into mitochondrion(GO:0035928)
0.1 1.8 GO:0007158 neuron cell-cell adhesion(GO:0007158)
0.1 0.7 GO:0045578 negative regulation of B cell differentiation(GO:0045578)
0.1 0.4 GO:0061181 regulation of chondrocyte development(GO:0061181)
0.1 0.4 GO:0071707 immunoglobulin heavy chain V-D-J recombination(GO:0071707)
0.1 0.4 GO:1900149 positive regulation of Schwann cell migration(GO:1900149)
0.1 0.7 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.1 0.5 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.1 0.8 GO:0007296 vitellogenesis(GO:0007296)
0.1 2.1 GO:0000920 cell separation after cytokinesis(GO:0000920)
0.1 0.4 GO:1904529 regulation of actin filament binding(GO:1904529) regulation of actin binding(GO:1904616)
0.1 0.2 GO:0002572 pro-T cell differentiation(GO:0002572)
0.1 0.4 GO:0070086 ubiquitin-dependent endocytosis(GO:0070086)
0.1 0.5 GO:0060279 regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.1 0.3 GO:2000686 regulation of rubidium ion transmembrane transporter activity(GO:2000686)
0.1 0.4 GO:0046013 T cell homeostatic proliferation(GO:0001777) regulation of T cell homeostatic proliferation(GO:0046013)
0.1 0.5 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.1 0.4 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966) regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000325) positive regulation of ligand-dependent nuclear receptor transcription coactivator activity(GO:2000327)
0.1 0.6 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.1 0.2 GO:0061537 glycine secretion(GO:0061536) glycine secretion, neurotransmission(GO:0061537)
0.1 0.5 GO:0030910 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.1 1.2 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.1 0.6 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.1 1.0 GO:0051292 nuclear pore complex assembly(GO:0051292)
0.1 0.5 GO:0070314 G1 to G0 transition(GO:0070314)
0.1 0.6 GO:0060339 negative regulation of type I interferon-mediated signaling pathway(GO:0060339)
0.1 0.2 GO:1902226 negative regulation of macrophage chemotaxis(GO:0010760) regulation of macrophage colony-stimulating factor signaling pathway(GO:1902226) regulation of response to macrophage colony-stimulating factor(GO:1903969) regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903972)
0.1 0.5 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
0.1 0.3 GO:0045590 negative regulation of regulatory T cell differentiation(GO:0045590)
0.1 0.1 GO:0060435 bronchiole development(GO:0060435)
0.1 0.3 GO:0001550 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.1 0.2 GO:0097401 synaptic vesicle lumen acidification(GO:0097401)
0.1 1.2 GO:0060539 diaphragm development(GO:0060539)
0.1 0.6 GO:0072619 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.1 0.2 GO:1990927 calcium ion regulated lysosome exocytosis(GO:1990927)
0.1 0.2 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.1 1.0 GO:0046069 cGMP catabolic process(GO:0046069)
0.1 0.2 GO:0002439 chronic inflammatory response to antigenic stimulus(GO:0002439)
0.1 0.8 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.1 0.4 GO:0010587 miRNA catabolic process(GO:0010587)
0.1 0.2 GO:0045204 MAPK export from nucleus(GO:0045204)
0.0 0.3 GO:0036515 serotonergic neuron axon guidance(GO:0036515)
0.0 0.3 GO:0089711 L-glutamate transmembrane transport(GO:0089711) L-alpha-amino acid transmembrane transport(GO:1902475)
0.0 0.2 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.0 0.4 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.0 0.1 GO:0044337 canonical Wnt signaling pathway involved in positive regulation of apoptotic process(GO:0044337)
0.0 0.2 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.0 0.4 GO:0010815 bradykinin catabolic process(GO:0010815) ubiquitin homeostasis(GO:0010992)
0.0 0.5 GO:0021684 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.0 0.5 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.0 0.8 GO:0038092 nodal signaling pathway(GO:0038092)
0.0 0.6 GO:0060836 lymphatic endothelial cell differentiation(GO:0060836)
0.0 0.7 GO:0048642 negative regulation of skeletal muscle tissue development(GO:0048642)
0.0 0.4 GO:0042118 endothelial cell activation(GO:0042118)
0.0 0.2 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.1 GO:1904245 regulation of polynucleotide adenylyltransferase activity(GO:1904245)
0.0 0.1 GO:0090365 regulation of mRNA modification(GO:0090365)
0.0 0.2 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.0 0.1 GO:0001928 regulation of exocyst assembly(GO:0001928)
0.0 1.4 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.9 GO:1903861 positive regulation of dendrite extension(GO:1903861)
0.0 0.3 GO:0033184 positive regulation of histone ubiquitination(GO:0033184)
0.0 0.5 GO:0006337 nucleosome disassembly(GO:0006337)
0.0 0.2 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
0.0 0.1 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.0 0.1 GO:0043973 histone H3-K4 acetylation(GO:0043973)
0.0 0.2 GO:0090527 actin filament reorganization(GO:0090527)
0.0 0.1 GO:1900825 regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900825)
0.0 0.1 GO:0010936 negative regulation of macrophage cytokine production(GO:0010936)
0.0 0.2 GO:0048630 skeletal muscle tissue growth(GO:0048630)
0.0 0.2 GO:0002568 somatic diversification of T cell receptor genes(GO:0002568) somatic recombination of T cell receptor gene segments(GO:0002681) T cell receptor V(D)J recombination(GO:0033153)
0.0 0.7 GO:0034453 microtubule anchoring(GO:0034453)
0.0 0.2 GO:0038031 non-canonical Wnt signaling pathway via JNK cascade(GO:0038031)
0.0 0.2 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
0.0 0.2 GO:0000320 re-entry into mitotic cell cycle(GO:0000320)
0.0 0.0 GO:0061152 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.0 0.3 GO:0042297 vocal learning(GO:0042297) imitative learning(GO:0098596)
0.0 0.1 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.0 0.1 GO:0021780 oligodendrocyte cell fate specification(GO:0021778) oligodendrocyte cell fate commitment(GO:0021779) glial cell fate specification(GO:0021780)
0.0 0.1 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
0.0 0.2 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 0.1 GO:1900039 positive regulation of cellular response to hypoxia(GO:1900039)
0.0 0.1 GO:0051866 general adaptation syndrome(GO:0051866)
0.0 0.5 GO:0021860 pyramidal neuron development(GO:0021860)
0.0 0.1 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.1 GO:0051013 microtubule severing(GO:0051013)
0.0 0.1 GO:0072697 protein localization to cell cortex(GO:0072697)
0.0 0.6 GO:0010842 retina layer formation(GO:0010842)
0.0 0.2 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.0 0.1 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.0 0.4 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)
0.0 0.1 GO:0021658 rhombomere 3 morphogenesis(GO:0021658)
0.0 0.5 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.0 0.6 GO:0070207 protein homotrimerization(GO:0070207)
0.0 0.2 GO:0060294 cilium movement involved in cell motility(GO:0060294)
0.0 0.2 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0 0.0 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
0.0 0.7 GO:0048384 retinoic acid receptor signaling pathway(GO:0048384)
0.0 0.1 GO:0036371 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.0 0.2 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.0 0.2 GO:0031424 keratinization(GO:0031424)
0.0 0.2 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.2 GO:0035988 chondrocyte proliferation(GO:0035988)
0.0 0.2 GO:0000729 DNA double-strand break processing(GO:0000729)
0.0 0.2 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.0 2.3 GO:1990830 response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)
0.0 0.1 GO:0060449 bud elongation involved in lung branching(GO:0060449)
0.0 0.1 GO:0030576 Cajal body organization(GO:0030576)
0.0 0.0 GO:0090649 response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.0 0.0 GO:0008582 regulation of synaptic growth at neuromuscular junction(GO:0008582)
0.0 0.4 GO:2000279 negative regulation of DNA biosynthetic process(GO:2000279)
0.0 0.0 GO:0003140 determination of left/right asymmetry in lateral mesoderm(GO:0003140)
0.0 0.1 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.0 0.2 GO:0033623 regulation of integrin activation(GO:0033623)
0.0 1.5 GO:0006261 DNA-dependent DNA replication(GO:0006261)
0.0 0.1 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.1 GO:0045760 positive regulation of action potential(GO:0045760)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.5 GO:0008623 CHRAC(GO:0008623)
0.3 1.5 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.3 0.9 GO:0042585 germinal vesicle(GO:0042585)
0.2 1.5 GO:0000235 astral microtubule(GO:0000235)
0.2 0.5 GO:0043512 inhibin A complex(GO:0043512)
0.2 2.4 GO:0042555 MCM complex(GO:0042555)
0.1 0.6 GO:0044530 supraspliceosomal complex(GO:0044530)
0.1 0.6 GO:0042025 host cell nucleus(GO:0042025) host cell nuclear part(GO:0044094)
0.1 2.1 GO:0016580 Sin3 complex(GO:0016580)
0.1 1.7 GO:0001518 voltage-gated sodium channel complex(GO:0001518)
0.1 0.6 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.1 0.3 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.0 0.1 GO:0031417 NatC complex(GO:0031417)
0.0 0.6 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.0 0.9 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 1.1 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.2 GO:0005896 interleukin-6 receptor complex(GO:0005896)
0.0 0.2 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 2.4 GO:0005871 kinesin complex(GO:0005871)
0.0 0.5 GO:0030061 mitochondrial crista(GO:0030061)
0.0 0.4 GO:0060091 kinocilium(GO:0060091)
0.0 0.4 GO:0031597 cytosolic proteasome complex(GO:0031597)
0.0 0.5 GO:0071564 npBAF complex(GO:0071564)
0.0 0.1 GO:0005726 perichromatin fibrils(GO:0005726)
0.0 2.7 GO:0017053 transcriptional repressor complex(GO:0017053)
0.0 0.2 GO:0036156 inner dynein arm(GO:0036156)
0.0 0.4 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.4 GO:0030014 CCR4-NOT complex(GO:0030014)
0.0 1.1 GO:0043034 costamere(GO:0043034)
0.0 0.2 GO:0097413 Lewy body(GO:0097413)
0.0 1.4 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.0 0.4 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.1 GO:0044305 calyx of Held(GO:0044305)
0.0 0.1 GO:0042405 nuclear inclusion body(GO:0042405)
0.0 0.2 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.2 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.2 GO:0032009 early phagosome(GO:0032009)
0.0 0.2 GO:0042581 specific granule(GO:0042581)
0.0 1.0 GO:0005643 nuclear pore(GO:0005643)
0.0 0.3 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.0 1.4 GO:0005913 cell-cell adherens junction(GO:0005913)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.7 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.2 0.6 GO:0005308 creatine transmembrane transporter activity(GO:0005308)
0.2 1.5 GO:0008310 single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310)
0.2 1.0 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.1 0.7 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.1 1.0 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1 0.8 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.1 1.0 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.1 0.6 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.1 1.0 GO:0034711 inhibin binding(GO:0034711)
0.1 0.5 GO:0004111 creatine kinase activity(GO:0004111)
0.1 0.6 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1 0.4 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 2.1 GO:0031402 sodium ion binding(GO:0031402)
0.1 0.4 GO:0004792 thiosulfate sulfurtransferase activity(GO:0004792)
0.1 0.3 GO:0000099 sulfur amino acid transmembrane transporter activity(GO:0000099)
0.1 0.7 GO:0035174 histone serine kinase activity(GO:0035174)
0.1 0.7 GO:1990948 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.1 0.2 GO:0035650 AP-1 adaptor complex binding(GO:0035650)
0.1 0.5 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.1 0.4 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.1 0.8 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.1 0.7 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.1 0.2 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.1 2.6 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.1 0.3 GO:0070012 oligopeptidase activity(GO:0070012)
0.1 0.4 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.1 1.1 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.1 1.1 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 0.2 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.0 0.5 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 1.2 GO:0008432 JUN kinase binding(GO:0008432)
0.0 1.0 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 4.1 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.7 GO:0031005 filamin binding(GO:0031005)
0.0 0.1 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.0 0.3 GO:0045322 unmethylated CpG binding(GO:0045322)
0.0 0.5 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.0 0.3 GO:0043559 insulin binding(GO:0043559)
0.0 1.7 GO:0070888 E-box binding(GO:0070888)
0.0 0.8 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 1.6 GO:0042805 actinin binding(GO:0042805)
0.0 0.2 GO:0003835 beta-galactoside alpha-2,6-sialyltransferase activity(GO:0003835)
0.0 0.5 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.0 0.1 GO:0071987 WD40-repeat domain binding(GO:0071987)
0.0 0.4 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.3 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.0 0.2 GO:0005283 sodium:amino acid symporter activity(GO:0005283)
0.0 0.3 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 0.1 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.0 0.1 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.0 0.6 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.2 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.7 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.0 0.2 GO:0005138 interleukin-6 receptor binding(GO:0005138)
0.0 0.0 GO:0001069 regulatory region RNA binding(GO:0001069)
0.0 0.5 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.0 0.8 GO:0018024 histone-lysine N-methyltransferase activity(GO:0018024)
0.0 0.3 GO:0043295 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)
0.0 0.5 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.5 GO:0071949 FAD binding(GO:0071949)
0.0 0.1 GO:0008568 microtubule-severing ATPase activity(GO:0008568)
0.0 1.6 GO:1990782 protein tyrosine kinase binding(GO:1990782)
0.0 0.4 GO:0004697 protein kinase C activity(GO:0004697)
0.0 0.8 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.0 0.2 GO:0001972 retinoic acid binding(GO:0001972)
0.0 0.2 GO:0042166 acetylcholine-gated cation channel activity(GO:0022848) acetylcholine binding(GO:0042166)
0.0 0.2 GO:0015197 peptide transporter activity(GO:0015197)
0.0 0.3 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.8 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.3 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.7 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 0.2 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.2 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.2 GO:0070530 K63-linked polyubiquitin binding(GO:0070530)
0.0 0.1 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.5 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 1.0 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.0 1.0 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.9 PID AURORA B PATHWAY Aurora B signaling
0.1 2.6 PID ATR PATHWAY ATR signaling pathway
0.0 0.9 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.7 PID BARD1 PATHWAY BARD1 signaling events
0.0 1.0 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.8 ST MYOCYTE AD PATHWAY Myocyte Adrenergic Pathway is a specific case of the generalized Adrenergic Pathway.
0.0 0.4 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.7 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.2 ST STAT3 PATHWAY STAT3 Pathway
0.0 1.1 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.6 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 1.6 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 1.2 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.7 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.6 PID ANGIOPOIETIN RECEPTOR PATHWAY Angiopoietin receptor Tie2-mediated signaling
0.0 0.5 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.7 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.8 PID SHP2 PATHWAY SHP2 signaling
0.0 0.3 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.4 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.1 1.5 REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.1 4.0 REACTOME AMINO ACID TRANSPORT ACROSS THE PLASMA MEMBRANE Genes involved in Amino acid transport across the plasma membrane
0.1 2.3 REACTOME KINESINS Genes involved in Kinesins
0.1 0.5 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.1 0.6 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.1 0.9 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.0 0.7 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 1.1 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.8 REACTOME DOWNREGULATION OF SMAD2 3 SMAD4 TRANSCRIPTIONAL ACTIVITY Genes involved in Downregulation of SMAD2/3:SMAD4 transcriptional activity
0.0 0.5 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.0 0.8 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.7 REACTOME SIGNALING BY FGFR1 FUSION MUTANTS Genes involved in Signaling by FGFR1 fusion mutants
0.0 0.2 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.2 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.0 0.2 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.5 REACTOME AMINO ACID AND OLIGOPEPTIDE SLC TRANSPORTERS Genes involved in Amino acid and oligopeptide SLC transporters
0.0 1.0 REACTOME CA DEPENDENT EVENTS Genes involved in Ca-dependent events
0.0 0.3 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 0.7 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.4 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.1 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.0 0.5 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 0.7 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.4 REACTOME CTLA4 INHIBITORY SIGNALING Genes involved in CTLA4 inhibitory signaling
0.0 0.1 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.2 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 1.1 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.8 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination