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2D miR_HR1_12

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Results for UAUUGCU

Z-value: 1.06

Motif logo

miRNA associated with seed UAUUGCU

NamemiRBASE accession
MIMAT0000149

Activity profile of UAUUGCU motif

Sorted Z-values of UAUUGCU motif

Promoter Log-likelihood Transcript Gene Gene Info
chr19_-_10457447 3.63 ENSMUST00000171400.2
leucine rich repeat containing 10B
chr17_+_69969073 1.58 ENSMUST00000133983.1
discs, large (Drosophila) homolog-associated protein 1
chr5_+_110879788 1.45 ENSMUST00000156290.2
ENSMUST00000040111.9
tetratricopeptide repeat domain 28
chr18_+_9212856 1.44 ENSMUST00000041080.5
frizzled homolog 8 (Drosophila)
chr12_+_24651346 1.31 ENSMUST00000020982.5
Kruppel-like factor 11
chr2_+_172345565 1.28 ENSMUST00000028995.4
family with sequence similarity 210, member B
chr13_-_52530827 1.24 ENSMUST00000057442.6
DIRAS family, GTP-binding RAS-like 2
chr1_-_51478390 1.20 ENSMUST00000027279.5
nucleic acid binding protein 1
chr5_-_103100054 1.17 ENSMUST00000112848.1
mitogen-activated protein kinase 10
chr12_-_78983476 1.11 ENSMUST00000070174.7
transmembrane protein 229B
chr8_+_82863351 1.08 ENSMUST00000078525.5
ring finger protein 150
chr17_+_8801742 1.04 ENSMUST00000089085.2
phosphodiesterase 10A
chr1_+_143640664 1.03 ENSMUST00000038252.2
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
chr1_+_184034381 1.01 ENSMUST00000048655.7
dual specificity phosphatase 10
chr17_+_72918298 0.99 ENSMUST00000024857.6
limb-bud and heart
chr10_-_61147659 0.98 ENSMUST00000092498.5
ENSMUST00000137833.1
ENSMUST00000155919.1
sphingosine phosphate lyase 1
chr8_-_38661508 0.98 ENSMUST00000118896.1
sarcoglycan zeta
chr8_+_69902178 0.97 ENSMUST00000050373.5
testis-specific serine kinase 6
chr3_+_107101551 0.97 ENSMUST00000038695.1
potassium voltage-gated channel, shaker-related subfamily, member 2
chr19_+_38836561 0.96 ENSMUST00000037302.5
TBC1D12: TBC1 domain family, member 12
chr15_-_75841907 0.95 ENSMUST00000100538.2
zinc finger CCCH type containing 3
chr9_+_121760000 0.93 ENSMUST00000093772.3
zinc finger protein 651
chr5_-_139813237 0.93 ENSMUST00000110832.1
transmembrane protein 184a
chr15_+_87625214 0.93 ENSMUST00000068088.6
family with sequence similarity 19, member A5
chr6_+_97807014 0.93 ENSMUST00000043637.7
microphthalmia-associated transcription factor
chr6_+_88724412 0.93 ENSMUST00000113585.2
monoglyceride lipase
chr13_+_38151324 0.92 ENSMUST00000127906.1
desmoplakin
chr13_-_34345174 0.89 ENSMUST00000040336.5
solute carrier family 22, member 23
chr3_+_96181151 0.88 ENSMUST00000035371.8
synaptic vesicle glycoprotein 2 a
chr1_-_190978954 0.87 ENSMUST00000047409.6
vasohibin 2
chr18_+_51117754 0.86 ENSMUST00000116639.2
proline rich 16
chr5_-_147894804 0.85 ENSMUST00000118527.1
ENSMUST00000031655.3
ENSMUST00000138244.1
solute carrier family 46, member 3
chr3_-_89387132 0.84 ENSMUST00000107433.1
zinc finger and BTB domain containing 7B
chr4_-_126533472 0.83 ENSMUST00000084289.4
argonaute RISC catalytic subunit 4
chr11_+_34314757 0.83 ENSMUST00000165963.1
ENSMUST00000093192.3
family with sequence similarity 196, member B
chr3_+_28263205 0.82 ENSMUST00000159236.2
TRAF2 and NCK interacting kinase
chr8_+_54077532 0.80 ENSMUST00000033919.4
vascular endothelial growth factor C
chr4_+_120854786 0.79 ENSMUST00000071093.2
regulating synaptic membrane exocytosis 3
chr7_-_127824469 0.78 ENSMUST00000106267.3
syntaxin 1B
chr19_+_53529100 0.78 ENSMUST00000038287.6
dual specificity phosphatase 5
chr5_+_66968416 0.78 ENSMUST00000038188.7
LIM and calponin homology domains 1
chr9_-_117252450 0.77 ENSMUST00000111773.3
ENSMUST00000068962.7
ENSMUST00000044901.7
RNA binding motif, single stranded interacting protein
chr2_+_21367532 0.76 ENSMUST00000055946.7
G protein-coupled receptor 158
chr15_-_101850778 0.75 ENSMUST00000023790.3
keratin 1
chr6_-_137649211 0.75 ENSMUST00000134630.1
ENSMUST00000058210.6
ENSMUST00000111878.1
epidermal growth factor receptor pathway substrate 8
chr13_-_92530813 0.74 ENSMUST00000022217.8
zinc finger, FYVE domain containing 16
chr13_-_13393592 0.73 ENSMUST00000021738.8
G protein-coupled receptor 137B
chr1_+_179546303 0.73 ENSMUST00000040706.8
consortin, connexin sorting protein
chr9_+_45370185 0.73 ENSMUST00000085939.6
FXYD domain-containing ion transport regulator 6
chr11_-_94474088 0.73 ENSMUST00000107786.1
ENSMUST00000107791.1
ENSMUST00000103166.2
ENSMUST00000107792.1
ENSMUST00000100561.3
ENSMUST00000107793.1
ENSMUST00000107788.1
ENSMUST00000107790.1
ENSMUST00000107789.1
ENSMUST00000107785.1
ENSMUST00000021234.8
calcium channel, voltage-dependent, T type, alpha 1G subunit
chr16_+_4886100 0.72 ENSMUST00000070658.8
ENSMUST00000023159.8
mahogunin, ring finger 1
chr8_-_90348343 0.70 ENSMUST00000109621.3
TOX high mobility group box family member 3
chr6_+_29768443 0.70 ENSMUST00000166718.1
ENSMUST00000102995.2
ENSMUST00000115242.2
S-adenosylhomocysteine hydrolase-like 2
chr8_+_106150359 0.69 ENSMUST00000034377.6
phospholipase A2, group XV
chr17_-_91092715 0.67 ENSMUST00000160800.2
ENSMUST00000159778.1
ENSMUST00000160844.3
neurexin I
chr18_+_67933257 0.67 ENSMUST00000063775.3
low density lipoprotein receptor class A domain containing 4
chr6_-_18514802 0.67 ENSMUST00000090601.5
cortactin binding protein 2
chr1_-_72874877 0.66 ENSMUST00000027377.8
insulin-like growth factor binding protein 5
chr1_-_126830632 0.65 ENSMUST00000112583.1
ENSMUST00000094609.3
NCK-associated protein 5
chr10_-_109010955 0.65 ENSMUST00000105276.1
ENSMUST00000064054.7
synaptotagmin I
chr8_+_76899772 0.64 ENSMUST00000109913.2
nuclear receptor subfamily 3, group C, member 2
chr15_-_76521902 0.64 ENSMUST00000164703.1
ENSMUST00000096365.3
scratch homolog 1, zinc finger protein (Drosophila)
chr17_-_33760451 0.62 ENSMUST00000057373.7
RAB11B, member RAS oncogene family
chr9_+_13827708 0.60 ENSMUST00000059579.5
family with sequence similarity 76, member B
chr13_+_94057757 0.60 ENSMUST00000054274.1
lipoma HMGIC fusion partner-like 2
chr4_+_42949814 0.59 ENSMUST00000037872.3
ENSMUST00000098112.2
DnaJ (Hsp40) homolog, subfamily B, member 5
chr5_+_134099704 0.59 ENSMUST00000016088.8
GATS protein-like 2
chr19_-_6992478 0.59 ENSMUST00000025915.5
DnaJ (Hsp40) homolog, subfamily C, member 4
chr17_+_35126316 0.59 ENSMUST00000061859.6
DNA segment, Chr 17, human D6S53E
chr15_-_71727815 0.58 ENSMUST00000022953.8
family with sequence similarity 135, member B
chr9_+_35211155 0.57 ENSMUST00000034541.5
signal recognition particle receptor ('docking protein')
chr10_+_79854618 0.57 ENSMUST00000165704.1
polypyrimidine tract binding protein 1
chr11_+_54438188 0.56 ENSMUST00000046835.7
folliculin interacting protein 1
chr12_-_41485751 0.56 ENSMUST00000043884.4
leucine rich repeat protein 3, neuronal
chr15_-_84447037 0.55 ENSMUST00000080751.2
RIKEN cDNA 1810041L15 gene
chr5_-_34187670 0.55 ENSMUST00000042701.6
ENSMUST00000119171.1
Max dimerization protein 4
chr12_+_71831064 0.55 ENSMUST00000085299.2
dishevelled associated activator of morphogenesis 1
chr14_-_12823031 0.55 ENSMUST00000067491.6
ENSMUST00000177814.1
ENSMUST00000112658.1
ENSMUST00000112657.2
Ca2+-dependent secretion activator
chr8_-_120589304 0.54 ENSMUST00000034278.5
GINS complex subunit 2 (Psf2 homolog)
chr11_-_86807624 0.54 ENSMUST00000018569.7
DEAH (Asp-Glu-Ala-His) box polypeptide 40
chr11_-_50292302 0.54 ENSMUST00000059458.4
mastermind like 1 (Drosophila)
chr16_+_11066292 0.54 ENSMUST00000089011.4
stannin
chr5_-_51553896 0.54 ENSMUST00000132734.1
peroxisome proliferative activated receptor, gamma, coactivator 1 alpha
chr16_+_8830093 0.53 ENSMUST00000023150.5
RIKEN cDNA 1810013L24 gene
chr11_-_60220550 0.52 ENSMUST00000020846.1
sterol regulatory element binding transcription factor 1
chr4_+_45965327 0.52 ENSMUST00000107777.2
tudor domain containing 7
chr2_+_79635352 0.52 ENSMUST00000111785.2
sperm specific antigen 2
chr3_+_134236483 0.51 ENSMUST00000181904.1
ENSMUST00000053048.9
CXXC finger 4
chr11_-_61855026 0.51 ENSMUST00000004920.3
unc-51 like kinase 2
chr6_+_47454320 0.50 ENSMUST00000031697.8
cullin 1
chr12_+_81631369 0.50 ENSMUST00000036116.5
tetratricopeptide repeat domain 9
chr5_+_138754514 0.50 ENSMUST00000026972.7
family with sequence similarity 20, member C
chr11_-_47379405 0.50 ENSMUST00000077221.5
sarcoglycan, delta (dystrophin-associated glycoprotein)
chr5_+_125532377 0.50 ENSMUST00000031446.6
transmembrane protein 132B
chr1_-_182517447 0.50 ENSMUST00000068505.8
calpain 2
chr3_+_88685785 0.49 ENSMUST00000029696.6
RIKEN cDNA 2810403A07 gene
chr5_+_119670825 0.49 ENSMUST00000121021.1
T-box 3
chr1_+_132417409 0.49 ENSMUST00000045110.7
dual serine/threonine and tyrosine protein kinase
chr17_-_26508463 0.49 ENSMUST00000025025.6
dual specificity phosphatase 1
chr2_+_162931520 0.48 ENSMUST00000130411.1
serine/arginine-rich splicing factor 6
chrX_-_17572241 0.48 ENSMUST00000176638.1
ENSMUST00000026016.6
FUN14 domain containing 1
chr13_-_43480973 0.47 ENSMUST00000144326.2
RAN binding protein 9
chr14_-_93888732 0.47 ENSMUST00000068992.2
protocadherin 9
chr5_+_110176640 0.47 ENSMUST00000112512.1
golgi autoantigen, golgin subfamily a, 3
chr13_-_103920508 0.47 ENSMUST00000053927.5
ENSMUST00000091269.4
ENSMUST00000022222.5
Erbb2 interacting protein
chr4_-_98817537 0.47 ENSMUST00000102790.3
KN motif and ankyrin repeat domains 4
chrX_+_103356464 0.47 ENSMUST00000116547.2
cysteine-rich hydrophobic domain 1
chr5_-_116024452 0.46 ENSMUST00000031486.7
protein kinase, AMP-activated, beta 1 non-catalytic subunit
chr6_-_112947246 0.46 ENSMUST00000088373.4
SLIT-ROBO Rho GTPase activating protein 3
chr18_-_33463615 0.46 ENSMUST00000051087.8
neuronal regeneration related protein
chr11_-_30025915 0.46 ENSMUST00000058902.5
echinoderm microtubule associated protein like 6
chr19_+_32619997 0.45 ENSMUST00000025833.6
3'-phosphoadenosine 5'-phosphosulfate synthase 2
chr5_+_135994796 0.45 ENSMUST00000111142.2
ENSMUST00000111145.3
ENSMUST00000111144.1
ENSMUST00000005072.3
ENSMUST00000130345.1
deltex 2 homolog (Drosophila)
chr15_-_102722150 0.45 ENSMUST00000023818.3
calcium binding and coiled coil domain 1
chr6_-_126645784 0.45 ENSMUST00000055168.3
potassium voltage-gated channel, shaker-related subfamily, member 1
chr3_-_58525867 0.44 ENSMUST00000029385.7
stress-associated endoplasmic reticulum protein 1
chr8_+_72319033 0.44 ENSMUST00000067912.7
Kruppel-like factor 2 (lung)
chr6_-_36811361 0.44 ENSMUST00000101534.1
pleiotrophin
chr6_+_36388055 0.44 ENSMUST00000172278.1
cholinergic receptor, muscarinic 2, cardiac
chr17_-_25433775 0.44 ENSMUST00000159610.1
ENSMUST00000159048.1
ENSMUST00000078496.5
calcium channel, voltage-dependent, T type, alpha 1H subunit
chr14_+_63436394 0.43 ENSMUST00000121288.1
family with sequence similarity 167, member A
chr1_+_59912972 0.42 ENSMUST00000036540.5
family with sequence similarity 117, member B
chr3_-_36690118 0.42 ENSMUST00000029271.4
transient receptor potential cation channel, subfamily C, member 3
chr10_-_86498836 0.42 ENSMUST00000120638.1
synapsin III
chr18_+_61555258 0.41 ENSMUST00000165123.1
casein kinase 1, alpha 1
chr13_+_25056206 0.41 ENSMUST00000069614.6
doublecortin domain containing 2a
chr19_+_8929628 0.41 ENSMUST00000096241.4
echinoderm microtubule associated protein like 3
chr3_+_137341067 0.41 ENSMUST00000122064.1
endomucin
chr12_-_4907705 0.41 ENSMUST00000020962.5
UBX domain protein 2A
chr2_-_26092149 0.40 ENSMUST00000114159.2
nucleus accumbens associated 2, BEN and BTB (POZ) domain containing
chr3_+_31902666 0.40 ENSMUST00000119970.1
ENSMUST00000178668.1
potassium large conductance calcium-activated channel, subfamily M, beta member 2
chr14_+_30479565 0.40 ENSMUST00000022535.7
DCP1 decapping enzyme homolog A (S. cerevisiae)
chr4_-_70534904 0.40 ENSMUST00000107359.2
multiple EGF-like-domains 9
chr15_+_89059712 0.40 ENSMUST00000161372.1
ENSMUST00000162424.1
pannexin 2
chr6_+_116338013 0.39 ENSMUST00000079012.6
ENSMUST00000101032.3
membrane-associated ring finger (C3HC4) 8
chr9_+_21165714 0.39 ENSMUST00000039413.8
phosphodiesterase 4A, cAMP specific
chr8_-_11008458 0.39 ENSMUST00000040514.6
insulin receptor substrate 2
chr13_-_12340723 0.39 ENSMUST00000168193.1
ENSMUST00000110616.1
ENSMUST00000064204.7
actinin alpha 2
chr14_+_70530819 0.39 ENSMUST00000047331.6
leucine-rich repeat LGI family, member 3
chr1_+_183297060 0.39 ENSMUST00000109166.2
axin interactor, dorsalization associated
chr6_-_29179584 0.39 ENSMUST00000159200.1
proline-rich transmembrane protein 4
chr7_+_58658181 0.39 ENSMUST00000168747.1
ATPase, class V, type 10A
chr1_+_131962941 0.39 ENSMUST00000177943.1
solute carrier family 45, member 3
chr1_+_134560190 0.38 ENSMUST00000112198.1
ENSMUST00000112197.1
lysine (K)-specific demethylase 5B
chr12_+_24831583 0.38 ENSMUST00000110942.3
ENSMUST00000078902.6
membrane bound O-acyltransferase domain containing 2
chr1_+_194619815 0.38 ENSMUST00000027952.5
plexin A2
chr2_+_152081529 0.38 ENSMUST00000064061.3
scratch homolog 2, zinc finger protein (Drosophila)
chr2_-_84715160 0.38 ENSMUST00000035840.5
zinc finger, DHHC domain containing 5
chr11_-_103954015 0.38 ENSMUST00000103075.4
N-ethylmaleimide sensitive fusion protein
chr1_-_13372434 0.37 ENSMUST00000081713.4
nuclear receptor coactivator 2
chr1_-_184999549 0.36 ENSMUST00000027929.4
MAP/microtubule affinity-regulating kinase 1
chr7_-_19562377 0.36 ENSMUST00000058444.8
protein phosphatase 1, regulatory subunit 37
chr17_+_36942910 0.36 ENSMUST00000040498.5
ring finger protein 39
chr1_-_38898084 0.36 ENSMUST00000027249.6
carbohydrate sulfotransferase 10
chr19_+_25672408 0.36 ENSMUST00000053068.5
doublesex and mab-3 related transcription factor 2
chr5_+_75574916 0.36 ENSMUST00000144270.1
ENSMUST00000005815.6
kit oncogene
chr14_+_14703025 0.36 ENSMUST00000057015.6
solute carrier family 4, sodium bicarbonate cotransporter, member 7
chr17_-_66077022 0.35 ENSMUST00000150766.1
ENSMUST00000038116.5
ankyrin repeat domain 12
chr9_-_22002599 0.35 ENSMUST00000115336.2
ENSMUST00000044926.5
coiled-coil domain containing 151
chr7_-_47008397 0.35 ENSMUST00000061639.7
SPT2, Suppressor of Ty, domain containing 1 (S. cerevisiae)
chr16_-_22657165 0.35 ENSMUST00000089925.3
diacylglycerol kinase, gamma
chr15_+_79108911 0.35 ENSMUST00000040320.8
microtubule associated monooxygenase, calponin and LIM domain containing -like 1
chr11_+_78536355 0.35 ENSMUST00000128788.1
intraflagellar transport 20
chr11_-_80779989 0.35 ENSMUST00000041065.7
ENSMUST00000070997.5
myosin ID
chr10_+_80115779 0.35 ENSMUST00000003152.7
serine/threonine kinase 11
chr12_-_91590009 0.35 ENSMUST00000021345.6
general transcription factor II A, 1
chr6_-_122486252 0.34 ENSMUST00000068242.6
ribosomal modification protein rimK-like family member B
chr8_-_83332416 0.34 ENSMUST00000177594.1
ENSMUST00000053902.3
ELMO/CED-12 domain containing 2
chr11_-_102556122 0.34 ENSMUST00000143842.1
G patch domain containing 8
chrY_-_1286563 0.34 ENSMUST00000091190.5
DEAD (Asp-Glu-Ala-Asp) box polypeptide 3, Y-linked
chr4_+_126103940 0.34 ENSMUST00000116286.2
ENSMUST00000094761.4
ENSMUST00000139524.1
serine/threonine kinase 40
chr1_-_164458345 0.34 ENSMUST00000027863.7
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr19_+_46599081 0.33 ENSMUST00000138302.2
ENSMUST00000099376.4
WW domain binding protein 1 like
chr5_-_36484112 0.33 ENSMUST00000119916.1
ENSMUST00000031097.7
transcriptional adaptor 2B
chr13_-_103334429 0.33 ENSMUST00000167058.1
ENSMUST00000164111.1
microtubule associated serine/threonine kinase family member 4
chr11_-_101119814 0.33 ENSMUST00000107295.3
family with sequence similarity 134, member C
chr4_-_118180043 0.32 ENSMUST00000106406.2
lysine (K)-specific demethylase 4A
chr7_+_126950518 0.32 ENSMUST00000106335.1
ENSMUST00000146017.1
seizure related 6 homolog like 2
chr9_+_108991902 0.32 ENSMUST00000147989.1
ENSMUST00000051873.8
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
chr13_+_104178797 0.32 ENSMUST00000022225.5
ENSMUST00000069187.5
tripartite motif-containing 23
chr5_+_107497718 0.31 ENSMUST00000112671.2
RIKEN cDNA A830010M20 gene
chr2_-_132578155 0.31 ENSMUST00000110136.1
ENSMUST00000124107.1
ENSMUST00000060955.5
glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae)
chr16_-_97962581 0.31 ENSMUST00000113734.2
ENSMUST00000052089.7
ENSMUST00000063605.7
zinc finger and BTB domain containing 21
chr4_-_155222535 0.31 ENSMUST00000084103.3
ENSMUST00000030917.5
ski sarcoma viral oncogene homolog (avian)
chr6_-_86669136 0.31 ENSMUST00000001184.7
MAX dimerization protein 1
chr11_-_102819114 0.31 ENSMUST00000068933.5
gap junction protein, gamma 1
chr19_+_56722372 0.31 ENSMUST00000038949.4
adrenergic receptor, beta 1
chr9_+_37489281 0.30 ENSMUST00000048604.6
Myb/SANT-like DNA-binding domain containing 2
chr13_+_9276477 0.30 ENSMUST00000174552.1
DIP2 disco-interacting protein 2 homolog C (Drosophila)
chr8_+_3393018 0.30 ENSMUST00000004684.6
ENSMUST00000145394.1
rho/rac guanine nucleotide exchange factor (GEF) 18
chr10_-_127211528 0.30 ENSMUST00000013970.7
phosphatidylinositol-5-phosphate 4-kinase, type II, gamma
chr1_+_172148015 0.30 ENSMUST00000074144.5
DDB1 and CUL4 associated factor 8
chr7_-_67372846 0.30 ENSMUST00000156690.1
ENSMUST00000107476.1
ENSMUST00000076325.5
ENSMUST00000032776.8
ENSMUST00000133074.1
myocyte enhancer factor 2A
chrX_-_152769461 0.30 ENSMUST00000101141.2
ENSMUST00000062317.4
shroom family member 2
chr13_-_58113592 0.29 ENSMUST00000160860.1
kelch-like 3
chr16_-_91011093 0.29 ENSMUST00000170853.1
ENSMUST00000118390.2
synaptojanin 1
chr9_+_118926453 0.29 ENSMUST00000073109.5
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
chr13_-_53377355 0.29 ENSMUST00000021920.6
serine palmitoyltransferase, long chain base subunit 1
chr15_-_37961059 0.28 ENSMUST00000022901.9
ribonucleotide reductase M2 B (TP53 inducible)
chr11_-_51857624 0.28 ENSMUST00000020655.7
ENSMUST00000109090.1
PHD finger protein 15

Network of associatons between targets according to the STRING database.

First level regulatory network of UAUUGCU

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0042998 positive regulation of Golgi to plasma membrane protein transport(GO:0042998) positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.2 0.6 GO:0031959 mineralocorticoid receptor signaling pathway(GO:0031959)
0.2 0.8 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.2 0.8 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.2 0.8 GO:1901492 positive regulation of lymphangiogenesis(GO:1901492)
0.2 0.8 GO:1904048 regulation of spontaneous neurotransmitter secretion(GO:1904048)
0.2 0.2 GO:0038189 neuropilin signaling pathway(GO:0038189) VEGF-activated neuropilin signaling pathway(GO:0038190) positive regulation of retinal ganglion cell axon guidance(GO:1902336)
0.2 1.1 GO:0007258 JUN phosphorylation(GO:0007258)
0.2 0.5 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.2 0.7 GO:0090126 protein complex assembly involved in synapse maturation(GO:0090126)
0.2 0.5 GO:0071895 odontoblast differentiation(GO:0071895)
0.2 0.7 GO:0014734 skeletal muscle hypertrophy(GO:0014734)
0.2 0.5 GO:0060932 atrioventricular bundle cell differentiation(GO:0003167) His-Purkinje system cell differentiation(GO:0060932)
0.2 1.0 GO:0021631 optic nerve morphogenesis(GO:0021631)
0.2 0.6 GO:0045054 constitutive secretory pathway(GO:0045054)
0.2 0.9 GO:0018992 germ-line sex determination(GO:0018992)
0.2 0.6 GO:2001137 positive regulation of endocytic recycling(GO:2001137)
0.2 0.5 GO:0003162 atrioventricular node development(GO:0003162)
0.1 0.3 GO:0070375 ERK5 cascade(GO:0070375)
0.1 0.4 GO:0050975 sensory perception of touch(GO:0050975)
0.1 1.0 GO:0060266 negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.1 0.4 GO:0010615 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244)
0.1 1.1 GO:1904672 regulation of somatic stem cell population maintenance(GO:1904672)
0.1 0.8 GO:0007256 activation of JNKK activity(GO:0007256)
0.1 0.5 GO:2000182 regulation of progesterone biosynthetic process(GO:2000182)
0.1 0.4 GO:1900477 negative regulation of G1/S transition of mitotic cell cycle by negative regulation of transcription from RNA polymerase II promoter(GO:1900477)
0.1 0.9 GO:0071896 protein localization to adherens junction(GO:0071896)
0.1 0.4 GO:2000016 negative regulation of determination of dorsal identity(GO:2000016)
0.1 0.4 GO:0015772 disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.1 0.4 GO:2000864 estradiol secretion(GO:0035938) regulation of estradiol secretion(GO:2000864)
0.1 0.4 GO:0021934 hindbrain tangential cell migration(GO:0021934)
0.1 1.6 GO:0070842 aggresome assembly(GO:0070842)
0.1 0.4 GO:1904349 positive regulation of small intestine smooth muscle contraction(GO:1904349)
0.1 1.0 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.1 0.3 GO:1903279 regulation of calcium:sodium antiporter activity(GO:1903279)
0.1 0.8 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.1 0.4 GO:0060221 retinal rod cell differentiation(GO:0060221) positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395)
0.1 1.1 GO:0005513 detection of calcium ion(GO:0005513)
0.1 1.0 GO:0010793 regulation of mRNA export from nucleus(GO:0010793)
0.1 0.6 GO:0071499 response to laminar fluid shear stress(GO:0034616) cellular response to laminar fluid shear stress(GO:0071499)
0.1 0.3 GO:1900135 positive regulation of the force of heart contraction by epinephrine-norepinephrine(GO:0001997) positive regulation of the force of heart contraction by chemical signal(GO:0003099) positive regulation of renin secretion into blood stream(GO:1900135)
0.1 0.7 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.1 0.3 GO:1904978 regulation of endosome organization(GO:1904978) positive regulation of endosome organization(GO:1904980)
0.1 1.0 GO:0035092 sperm chromatin condensation(GO:0035092)
0.1 0.2 GO:2000744 anterior head development(GO:0097065) regulation of anterior head development(GO:2000742) positive regulation of anterior head development(GO:2000744)
0.1 0.3 GO:0006667 sphinganine metabolic process(GO:0006667)
0.1 0.7 GO:0010991 negative regulation of SMAD protein complex assembly(GO:0010991)
0.1 0.8 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.1 1.5 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.1 0.6 GO:2000973 regulation of pro-B cell differentiation(GO:2000973)
0.1 0.5 GO:0099525 presynaptic dense core granule exocytosis(GO:0099525)
0.1 0.5 GO:0000727 double-strand break repair via break-induced replication(GO:0000727)
0.1 0.5 GO:0000103 sulfate assimilation(GO:0000103)
0.1 0.4 GO:0061055 myotome development(GO:0061055)
0.1 0.4 GO:0021747 cochlear nucleus development(GO:0021747)
0.1 0.3 GO:0060066 oviduct development(GO:0060066)
0.1 0.4 GO:0010847 regulation of chromatin assembly(GO:0010847)
0.1 0.9 GO:0014052 regulation of gamma-aminobutyric acid secretion(GO:0014052)
0.1 0.4 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.1 0.2 GO:0034224 cellular response to zinc ion starvation(GO:0034224)
0.1 0.5 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.1 0.1 GO:0060268 negative regulation of respiratory burst(GO:0060268)
0.1 0.4 GO:0045347 negative regulation of MHC class II biosynthetic process(GO:0045347)
0.1 0.3 GO:0086053 AV node cell to bundle of His cell communication by electrical coupling(GO:0086053)
0.1 0.9 GO:0044336 canonical Wnt signaling pathway involved in negative regulation of apoptotic process(GO:0044336)
0.1 1.1 GO:0033327 Leydig cell differentiation(GO:0033327)
0.1 0.1 GO:0097112 gamma-aminobutyric acid receptor clustering(GO:0097112)
0.1 0.7 GO:0043951 negative regulation of cAMP-mediated signaling(GO:0043951)
0.1 0.1 GO:0061762 CAMKK-AMPK signaling cascade(GO:0061762)
0.1 0.4 GO:0060124 positive regulation of growth hormone secretion(GO:0060124)
0.1 0.5 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.1 0.5 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
0.1 0.1 GO:0001831 trophectodermal cellular morphogenesis(GO:0001831)
0.1 0.5 GO:0003062 regulation of heart rate by chemical signal(GO:0003062)
0.1 0.2 GO:0035694 mitochondrial protein catabolic process(GO:0035694)
0.1 0.2 GO:0071211 protein targeting to vacuole involved in autophagy(GO:0071211)
0.1 0.4 GO:0034651 cortisol metabolic process(GO:0034650) cortisol biosynthetic process(GO:0034651)
0.1 0.3 GO:0051902 negative regulation of mitochondrial depolarization(GO:0051902)
0.1 0.2 GO:1900247 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
0.1 0.2 GO:0001827 inner cell mass cell fate commitment(GO:0001827)
0.1 0.4 GO:1904016 positive regulation of female receptivity(GO:0045925) response to Thyroglobulin triiodothyronine(GO:1904016) cellular response to Thyroglobulin triiodothyronine(GO:1904017)
0.1 0.4 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.1 0.3 GO:0071692 protein localization to extracellular region(GO:0071692) maintenance of protein location in extracellular region(GO:0071694)
0.1 0.3 GO:0043585 negative regulation of Schwann cell proliferation(GO:0010626) nose morphogenesis(GO:0043585)
0.1 0.5 GO:0035878 nail development(GO:0035878)
0.1 0.3 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.1 0.5 GO:0075044 autophagy of host cells involved in interaction with symbiont(GO:0075044) autophagy involved in symbiotic interaction(GO:0075071)
0.0 0.2 GO:2000035 regulation of stem cell division(GO:2000035)
0.0 0.4 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 1.4 GO:0043949 regulation of cAMP-mediated signaling(GO:0043949)
0.0 0.0 GO:1990535 neuron projection maintenance(GO:1990535)
0.0 0.6 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.0 0.1 GO:0099526 presynaptic signal transduction(GO:0098928) presynapse to nucleus signaling pathway(GO:0099526)
0.0 0.1 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.0 0.1 GO:0035799 ureter maturation(GO:0035799)
0.0 0.7 GO:0006622 protein targeting to lysosome(GO:0006622)
0.0 0.2 GO:0051890 regulation of cardioblast differentiation(GO:0051890)
0.0 0.3 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.0 1.5 GO:0001706 endoderm formation(GO:0001706)
0.0 0.2 GO:0045924 regulation of female receptivity(GO:0045924)
0.0 0.2 GO:0045048 protein insertion into ER membrane(GO:0045048)
0.0 0.2 GO:0021764 amygdala development(GO:0021764)
0.0 0.2 GO:0071442 N-terminal peptidyl-lysine acetylation(GO:0018076) positive regulation of histone H3-K14 acetylation(GO:0071442)
0.0 0.8 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.0 0.6 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 0.2 GO:0034773 histone H4-K20 trimethylation(GO:0034773)
0.0 0.2 GO:0035063 nuclear speck organization(GO:0035063)
0.0 0.1 GO:0036414 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.0 0.6 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 1.6 GO:2000785 regulation of autophagosome assembly(GO:2000785)
0.0 0.8 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.0 GO:1900275 negative regulation of phospholipase C activity(GO:1900275)
0.0 0.2 GO:0000429 carbon catabolite regulation of transcription from RNA polymerase II promoter(GO:0000429) regulation of transcription from RNA polymerase II promoter by glucose(GO:0000430) positive regulation of transcription from RNA polymerase II promoter by glucose(GO:0000432) carbon catabolite activation of transcription from RNA polymerase II promoter(GO:0000436)
0.0 0.4 GO:0031468 nuclear envelope reassembly(GO:0031468)
0.0 0.3 GO:0070294 renal sodium ion absorption(GO:0070294)
0.0 0.1 GO:0044313 protein K6-linked deubiquitination(GO:0044313)
0.0 0.3 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.4 GO:0002903 negative regulation of B cell apoptotic process(GO:0002903)
0.0 0.2 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.0 0.4 GO:1904424 regulation of GTP binding(GO:1904424)
0.0 0.2 GO:0098886 modification of dendritic spine(GO:0098886)
0.0 0.1 GO:0060596 mammary placode formation(GO:0060596)
0.0 0.2 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.0 0.1 GO:0060854 patterning of lymph vessels(GO:0060854)
0.0 0.3 GO:0031274 positive regulation of pseudopodium assembly(GO:0031274)
0.0 0.1 GO:0001661 conditioned taste aversion(GO:0001661)
0.0 0.2 GO:0006451 selenocysteine incorporation(GO:0001514) translational readthrough(GO:0006451)
0.0 0.4 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 0.5 GO:0016540 protein autoprocessing(GO:0016540)
0.0 0.2 GO:0003105 negative regulation of glomerular filtration(GO:0003105)
0.0 0.1 GO:0006538 glutamate catabolic process(GO:0006538)
0.0 0.3 GO:0030643 cellular phosphate ion homeostasis(GO:0030643) cellular divalent inorganic anion homeostasis(GO:0072501) cellular trivalent inorganic anion homeostasis(GO:0072502)
0.0 0.2 GO:0090091 positive regulation of extracellular matrix disassembly(GO:0090091) negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0 0.1 GO:0021553 olfactory nerve development(GO:0021553)
0.0 0.9 GO:0045026 plasma membrane fusion(GO:0045026)
0.0 0.2 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.0 0.1 GO:1903976 negative regulation of glial cell migration(GO:1903976)
0.0 0.1 GO:1903371 regulation of endoplasmic reticulum tubular network organization(GO:1903371)
0.0 0.3 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)
0.0 0.3 GO:0045176 apical protein localization(GO:0045176)
0.0 0.1 GO:0044821 meiotic telomere tethering at nuclear periphery(GO:0044821) meiotic attachment of telomere to nuclear envelope(GO:0070197) chromosome attachment to the nuclear envelope(GO:0097240)
0.0 0.1 GO:0061033 secretion by lung epithelial cell involved in lung growth(GO:0061033)
0.0 0.3 GO:0036010 protein localization to endosome(GO:0036010)
0.0 0.1 GO:0010747 positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747)
0.0 0.2 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.1 GO:0033078 extrathymic T cell differentiation(GO:0033078)
0.0 0.0 GO:2000729 positive regulation of mesenchymal cell proliferation involved in ureter development(GO:2000729)
0.0 0.3 GO:0009200 deoxyribonucleoside triphosphate metabolic process(GO:0009200)
0.0 0.5 GO:2000300 regulation of synaptic vesicle exocytosis(GO:2000300)
0.0 0.1 GO:0060017 parathyroid gland development(GO:0060017)
0.0 1.4 GO:0035567 non-canonical Wnt signaling pathway(GO:0035567)
0.0 0.2 GO:0009143 nucleoside triphosphate catabolic process(GO:0009143)
0.0 0.0 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.0 0.1 GO:0060178 regulation of exocyst localization(GO:0060178)
0.0 0.2 GO:0043584 nose development(GO:0043584)
0.0 0.1 GO:1901165 positive regulation of trophoblast cell migration(GO:1901165)
0.0 0.1 GO:0006613 cotranslational protein targeting to membrane(GO:0006613)
0.0 0.1 GO:0098969 neurotransmitter receptor transport to postsynaptic membrane(GO:0098969) establishment of protein localization to postsynaptic membrane(GO:1903540)
0.0 0.4 GO:0001921 positive regulation of receptor recycling(GO:0001921)
0.0 0.1 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 0.1 GO:1904995 positive regulation of axon extension involved in axon guidance(GO:0048842) negative regulation of leukocyte tethering or rolling(GO:1903237) negative regulation of leukocyte adhesion to vascular endothelial cell(GO:1904995)
0.0 0.5 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.2 GO:1904322 activation of adenylate cyclase activity(GO:0007190) response to forskolin(GO:1904321) cellular response to forskolin(GO:1904322)
0.0 0.5 GO:0051497 negative regulation of stress fiber assembly(GO:0051497)
0.0 0.6 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.3 GO:0090036 regulation of protein kinase C signaling(GO:0090036)
0.0 0.1 GO:0016557 peroxisome membrane biogenesis(GO:0016557)
0.0 0.2 GO:0071420 cellular response to histamine(GO:0071420)
0.0 0.0 GO:0006011 UDP-glucose metabolic process(GO:0006011) glucose 1-phosphate metabolic process(GO:0019255)
0.0 0.2 GO:0010225 response to UV-C(GO:0010225)
0.0 0.0 GO:0006097 glyoxylate cycle(GO:0006097)
0.0 0.2 GO:0043586 tongue development(GO:0043586)
0.0 0.1 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 0.4 GO:0002931 response to ischemia(GO:0002931)
0.0 0.2 GO:0045475 locomotor rhythm(GO:0045475)
0.0 0.3 GO:0003016 respiratory system process(GO:0003016)
0.0 0.1 GO:1902035 positive regulation of hematopoietic stem cell proliferation(GO:1902035)
0.0 0.4 GO:0007616 long-term memory(GO:0007616)
0.0 0.0 GO:1905051 regulation of base-excision repair(GO:1905051) positive regulation of base-excision repair(GO:1905053)
0.0 0.3 GO:0035066 positive regulation of histone acetylation(GO:0035066)
0.0 0.1 GO:0036315 cellular response to sterol(GO:0036315)
0.0 0.1 GO:0032328 alanine transport(GO:0032328)
0.0 0.4 GO:0045880 positive regulation of smoothened signaling pathway(GO:0045880)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:1990851 Wnt-Frizzled-LRP5/6 complex(GO:1990851)
0.2 1.2 GO:0070876 SOSS complex(GO:0070876)
0.2 1.5 GO:0016012 sarcoglycan complex(GO:0016012)
0.2 0.5 GO:0000811 GINS complex(GO:0000811)
0.1 1.8 GO:0001533 cornified envelope(GO:0001533)
0.1 0.5 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.1 1.5 GO:1990023 mitotic spindle midzone(GO:1990023)
0.1 0.5 GO:0090498 extrinsic component of Golgi membrane(GO:0090498)
0.1 0.5 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.1 0.3 GO:1902636 kinociliary basal body(GO:1902636)
0.1 0.7 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.1 0.9 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.1 0.3 GO:0035339 SPOTS complex(GO:0035339)
0.1 0.6 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.1 1.4 GO:0044224 juxtaparanode region of axon(GO:0044224)
0.1 1.2 GO:0031045 dense core granule(GO:0031045)
0.1 0.2 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.1 1.4 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.1 0.3 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.1 0.3 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.0 0.6 GO:0061700 GATOR2 complex(GO:0061700)
0.0 1.9 GO:0048786 presynaptic active zone(GO:0048786)
0.0 0.7 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.9 GO:0043196 varicosity(GO:0043196)
0.0 0.3 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 0.4 GO:0060091 kinocilium(GO:0060091)
0.0 0.7 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.2 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.0 0.6 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.2 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.0 0.2 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.0 0.2 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.3 GO:0070695 FHF complex(GO:0070695)
0.0 0.5 GO:0033391 chromatoid body(GO:0033391)
0.0 0.2 GO:0097443 sorting endosome(GO:0097443)
0.0 0.2 GO:0000125 PCAF complex(GO:0000125)
0.0 0.6 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.3 GO:0070578 RISC-loading complex(GO:0070578)
0.0 1.4 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 1.6 GO:0031901 early endosome membrane(GO:0031901)
0.0 0.5 GO:0031143 pseudopodium(GO:0031143)
0.0 1.0 GO:0097440 apical dendrite(GO:0097440)
0.0 0.3 GO:0030914 STAGA complex(GO:0030914)
0.0 0.1 GO:0034657 GID complex(GO:0034657)
0.0 0.1 GO:0016939 kinesin II complex(GO:0016939)
0.0 0.1 GO:0005827 polar microtubule(GO:0005827)
0.0 0.0 GO:0005899 insulin receptor complex(GO:0005899)
0.0 0.0 GO:0098855 HCN channel complex(GO:0098855)
0.0 0.5 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.5 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 1.8 GO:0055037 recycling endosome(GO:0055037)
0.0 0.3 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.3 GO:0005922 connexon complex(GO:0005922)
0.0 0.3 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.4 GO:0005865 striated muscle thin filament(GO:0005865)
0.0 0.2 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.1 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.0 0.2 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.2 GO:0043203 axon hillock(GO:0043203)
0.0 0.2 GO:1902711 GABA receptor complex(GO:1902710) GABA-A receptor complex(GO:1902711)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.1 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.3 1.1 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.3 1.0 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.3 0.8 GO:0030280 structural constituent of epidermis(GO:0030280)
0.2 0.7 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.2 0.6 GO:0017082 mineralocorticoid receptor activity(GO:0017082)
0.2 0.7 GO:0030348 syntaxin-3 binding(GO:0030348)
0.1 1.0 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.1 0.4 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.1 0.8 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.1 0.4 GO:0015157 sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.1 1.7 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 0.7 GO:0034056 estrogen response element binding(GO:0034056)
0.1 1.1 GO:0071253 connexin binding(GO:0071253)
0.1 0.5 GO:0032810 sterol response element binding(GO:0032810)
0.1 0.3 GO:0086075 gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075) gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling(GO:0086077)
0.1 0.3 GO:0051380 norepinephrine binding(GO:0051380)
0.1 0.3 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.1 0.4 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.1 0.6 GO:0001069 regulatory region RNA binding(GO:0001069)
0.1 0.7 GO:0030375 thyroid hormone receptor coactivator activity(GO:0030375)
0.1 0.4 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.1 0.7 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.1 0.4 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.1 0.6 GO:0005047 signal recognition particle binding(GO:0005047)
0.1 0.7 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.1 0.3 GO:0047389 glycerophosphocholine phosphodiesterase activity(GO:0047389)
0.1 0.3 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1 0.7 GO:0047499 calcium-independent phospholipase A2 activity(GO:0047499)
0.1 0.7 GO:0015271 outward rectifier potassium channel activity(GO:0015271)
0.1 0.4 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.1 1.4 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.1 1.0 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.1 0.4 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1 0.8 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.1 0.3 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.1 0.3 GO:0002046 opsin binding(GO:0002046)
0.1 0.4 GO:0042289 MHC class II protein binding(GO:0042289)
0.1 0.3 GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.1 0.7 GO:0097109 neuroligin family protein binding(GO:0097109)
0.1 0.4 GO:0004716 receptor signaling protein tyrosine kinase activity(GO:0004716)
0.1 0.2 GO:0005006 epidermal growth factor-activated receptor activity(GO:0005006)
0.0 0.2 GO:0005223 intracellular cGMP activated cation channel activity(GO:0005223)
0.0 0.1 GO:0070905 serine binding(GO:0070905)
0.0 0.2 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.2 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.0 0.3 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.0 0.2 GO:0022851 GABA-gated chloride ion channel activity(GO:0022851)
0.0 0.4 GO:0005243 gap junction channel activity(GO:0005243)
0.0 0.1 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.0 0.2 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 0.6 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.0 1.7 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.3 GO:0001515 opioid peptide activity(GO:0001515)
0.0 0.9 GO:0042056 chemoattractant activity(GO:0042056)
0.0 0.3 GO:0004331 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
0.0 0.7 GO:0070300 phosphatidic acid binding(GO:0070300)
0.0 0.2 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.0 0.3 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.1 GO:0001225 RNA polymerase II transcription coactivator binding(GO:0001225)
0.0 0.2 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.0 0.4 GO:0015279 store-operated calcium channel activity(GO:0015279) inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0 0.5 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.0 0.2 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.5 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.5 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.2 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.0 0.1 GO:0048763 ryanodine-sensitive calcium-release channel activity(GO:0005219) calcium-induced calcium release activity(GO:0048763)
0.0 0.1 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.6 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)
0.0 0.2 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
0.0 0.2 GO:0045545 syndecan binding(GO:0045545)
0.0 0.1 GO:0031208 POZ domain binding(GO:0031208)
0.0 0.4 GO:0043008 ATP-dependent protein binding(GO:0043008)
0.0 0.4 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.6 GO:0031489 myosin V binding(GO:0031489)
0.0 0.4 GO:0033130 acetylcholine receptor binding(GO:0033130)
0.0 0.2 GO:0016618 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.0 0.2 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.0 0.2 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.2 GO:0043423 3-phosphoinositide-dependent protein kinase binding(GO:0043423)
0.0 0.4 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.0 0.1 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 0.1 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.4 GO:0030898 actin-dependent ATPase activity(GO:0030898)
0.0 0.2 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.1 GO:0004351 glutamate decarboxylase activity(GO:0004351)
0.0 0.1 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.0 0.1 GO:0008142 oxysterol binding(GO:0008142)
0.0 0.4 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.1 GO:0004028 3-chloroallyl aldehyde dehydrogenase activity(GO:0004028)
0.0 0.3 GO:0030275 LRR domain binding(GO:0030275)
0.0 0.2 GO:0046870 cadmium ion binding(GO:0046870)
0.0 0.3 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.3 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.4 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.3 GO:0048018 receptor agonist activity(GO:0048018)
0.0 0.1 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.2 GO:0004887 thyroid hormone receptor activity(GO:0004887) thyroid hormone binding(GO:0070324)
0.0 0.5 GO:0042605 peptide antigen binding(GO:0042605)
0.0 0.4 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.5 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.2 GO:0000182 rDNA binding(GO:0000182)
0.0 0.3 GO:0035198 miRNA binding(GO:0035198)
0.0 1.3 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 0.6 GO:0071889 14-3-3 protein binding(GO:0071889)
0.0 0.1 GO:0086007 voltage-gated calcium channel activity involved in cardiac muscle cell action potential(GO:0086007)
0.0 0.2 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.1 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 0.6 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.9 GO:0097110 scaffold protein binding(GO:0097110)
0.0 0.7 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.4 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 0.3 GO:0004198 calcium-dependent cysteine-type endopeptidase activity(GO:0004198)
0.0 0.4 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.0 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.0 0.2 GO:0017166 vinculin binding(GO:0017166)
0.0 0.2 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.0 0.1 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.0 0.1 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.8 GO:0003724 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004)
0.0 1.4 GO:0003705 transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0003705)
0.0 0.2 GO:0017110 nucleoside-diphosphatase activity(GO:0017110)
0.0 0.1 GO:0019788 NEDD8 transferase activity(GO:0019788)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 2.1 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 3.0 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 0.9 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.6 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.7 PID SYNDECAN 3 PATHWAY Syndecan-3-mediated signaling events
0.0 1.6 PID BMP PATHWAY BMP receptor signaling
0.0 0.5 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin
0.0 0.7 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 2.4 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.5 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.4 PID PI3K PLC TRK PATHWAY Trk receptor signaling mediated by PI3K and PLC-gamma
0.0 0.7 PID KIT PATHWAY Signaling events mediated by Stem cell factor receptor (c-Kit)
0.0 0.4 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 0.4 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.4 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.2 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.9 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.6 PID IGF1 PATHWAY IGF1 pathway
0.0 0.5 PID AURORA A PATHWAY Aurora A signaling
0.0 0.2 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 0.2 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 0.7 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 0.2 PID MET PATHWAY Signaling events mediated by Hepatocyte Growth Factor Receptor (c-Met)
0.0 0.4 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.4 REACTOME BOTULINUM NEUROTOXICITY Genes involved in Botulinum neurotoxicity
0.1 1.0 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.1 0.4 REACTOME NEURONAL SYSTEM Genes involved in Neuronal System
0.1 1.0 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1 1.1 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.9 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 0.4 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.7 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.5 REACTOME CYTOSOLIC SULFONATION OF SMALL MOLECULES Genes involved in Cytosolic sulfonation of small molecules
0.0 1.2 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 1.3 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.7 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 1.1 REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION Genes involved in RORA Activates Circadian Expression
0.0 0.5 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.5 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.2 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.5 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.6 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 1.2 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.5 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.4 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 1.1 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.3 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 0.2 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.0 0.7 REACTOME AMINE LIGAND BINDING RECEPTORS Genes involved in Amine ligand-binding receptors
0.0 1.1 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.3 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 1.0 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 1.7 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.2 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.1 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 0.4 REACTOME ACYL CHAIN REMODELLING OF PC Genes involved in Acyl chain remodelling of PC
0.0 0.3 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.7 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.4 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.2 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.4 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.1 REACTOME ION CHANNEL TRANSPORT Genes involved in Ion channel transport
0.0 0.3 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.1 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.2 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.4 REACTOME STRIATED MUSCLE CONTRACTION Genes involved in Striated Muscle Contraction
0.0 0.1 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 0.5 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.0 0.2 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.3 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.2 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.2 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors