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2D miR_HR1_12

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Results for Cdx2

Z-value: 0.61

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Transcription factors associated with Cdx2

Gene Symbol Gene ID Gene Info
ENSMUSG00000029646.3 caudal type homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Cdx2mm10_v2_chr5_-_147307264_147307281-0.382.2e-01Click!

Activity profile of Cdx2 motif

Sorted Z-values of Cdx2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr6_+_71199827 1.32 ENSMUST00000067492.7
fatty acid binding protein 1, liver
chr2_-_24048857 1.13 ENSMUST00000114497.1
histamine N-methyltransferase
chr7_+_131032061 1.13 ENSMUST00000084509.3
deleted in malignant brain tumors 1
chr16_-_44016387 0.85 ENSMUST00000036174.3
GRAM domain containing 1C
chr13_+_89540636 0.65 ENSMUST00000022108.7
hyaluronan and proteoglycan link protein 1
chr8_-_105933832 0.54 ENSMUST00000034368.6
chymotrypsin-like
chr17_-_90088343 0.51 ENSMUST00000173917.1
neurexin I
chr3_-_90695706 0.50 ENSMUST00000069960.5
ENSMUST00000117167.1
S100 calcium binding protein A9 (calgranulin B)
chr9_-_21989427 0.50 ENSMUST00000045726.6
ral guanine nucleotide dissociation stimulator-like 3
chrX_+_164140447 0.49 ENSMUST00000073973.4
angiotensin I converting enzyme (peptidyl-dipeptidase A) 2
chr11_+_87663087 0.47 ENSMUST00000165679.1
ring finger protein 43
chr3_+_40540751 0.45 ENSMUST00000091186.3
inturned planar cell polarity effector homolog (Drosophila)
chr11_-_99979053 0.45 ENSMUST00000105051.1
keratin associated protein 29-1
chr6_-_13839916 0.44 ENSMUST00000060442.7
G protein-coupled receptor 85
chr18_+_37755718 0.38 ENSMUST00000061279.7
protocadherin gamma subfamily A, 9
chr3_+_3634145 0.37 ENSMUST00000108394.1
hepatocyte nuclear factor 4, gamma
chrX_+_139684980 0.35 ENSMUST00000096313.3
TBC1 domain family, member 8B
chr6_+_38918969 0.33 ENSMUST00000003017.6
thromboxane A synthase 1, platelet
chr17_-_91092715 0.32 ENSMUST00000160800.2
ENSMUST00000159778.1
ENSMUST00000160844.3
neurexin I
chr2_+_74721978 0.32 ENSMUST00000047904.3
homeobox D3
chr3_+_126597415 0.31 ENSMUST00000066452.7
ENSMUST00000171289.1
ENSMUST00000106399.1
calcium/calmodulin-dependent protein kinase II, delta
chr11_-_99244058 0.31 ENSMUST00000103132.3
ENSMUST00000038214.6
keratin 222
chr3_+_126597299 0.30 ENSMUST00000106400.2
ENSMUST00000106401.1
calcium/calmodulin-dependent protein kinase II, delta
chr8_+_54550324 0.30 ENSMUST00000033918.2
ankyrin repeat and SOCs box-containing 5
chr11_-_99438143 0.27 ENSMUST00000017743.2
keratin 20
chr19_+_8850785 0.26 ENSMUST00000096257.2
LRRN4 C-terminal like
chr19_-_34879452 0.26 ENSMUST00000036584.5
pantothenate kinase 1
chr12_+_113074475 0.25 ENSMUST00000012355.7
ENSMUST00000146107.1
testis expressed gene 22
chr18_+_37513652 0.23 ENSMUST00000061405.4
protocadherin beta 21
chr4_-_137118135 0.22 ENSMUST00000154285.1
predicted gene 13001
chr1_-_169747634 0.22 ENSMUST00000027991.5
ENSMUST00000111357.1
regulator of G-protein signaling 4
chr16_-_79091078 0.21 ENSMUST00000023566.4
ENSMUST00000060402.5
transmembrane protease, serine 15
chr17_+_80307396 0.20 ENSMUST00000068175.5
Rho guanine nucleotide exchange factor (GEF) 33
chr11_+_96323253 0.20 ENSMUST00000093944.3
homeobox B3
chrX_-_51205990 0.18 ENSMUST00000114876.2
muscleblind-like 3 (Drosophila)
chr10_+_118204942 0.18 ENSMUST00000096691.4
interleukin 22
chr14_+_80000292 0.18 ENSMUST00000088735.3
olfactomedin 4
chr4_+_144893127 0.17 ENSMUST00000142808.1
dehydrogenase/reductase (SDR family) member 3
chr15_+_23036449 0.16 ENSMUST00000164787.1
cadherin 18
chr4_-_109202217 0.13 ENSMUST00000160774.1
ENSMUST00000030288.7
ENSMUST00000162787.2
oxysterol binding protein-like 9
chr1_-_89933290 0.13 ENSMUST00000036954.7
gastrulation brain homeobox 2
chr6_-_122340525 0.13 ENSMUST00000112600.2
polyhomeotic-like 1 (Drosophila)
chr12_+_113074756 0.12 ENSMUST00000109729.2
testis expressed gene 22
chr12_+_77238093 0.12 ENSMUST00000177595.1
ENSMUST00000171770.2
fucosyltransferase 8
chr7_-_139582790 0.11 ENSMUST00000106095.2
NK6 homeobox 2
chr11_-_79504078 0.10 ENSMUST00000164465.2
oligodendrocyte myelin glycoprotein
chr13_-_107890059 0.09 ENSMUST00000105097.2
zinc finger SWIM-type containing 6
chr18_+_65582390 0.09 ENSMUST00000169679.1
ENSMUST00000183326.1
zinc finger protein 532
chr1_-_186705980 0.08 ENSMUST00000045288.8
transforming growth factor, beta 2
chr13_-_23934156 0.08 ENSMUST00000052776.2
histone cluster 1, H2ba
chr6_-_71262232 0.08 ENSMUST00000129630.2
ENSMUST00000114186.2
ENSMUST00000074301.3
SET and MYND domain containing 1
chrX_+_164090187 0.08 ENSMUST00000015545.3
transmembrane protein 27
chr11_-_99993992 0.08 ENSMUST00000105049.1
keratin associated protein 17-1
chr3_-_92485886 0.08 ENSMUST00000054599.7
small proline-rich protein 1A
chr14_+_54686171 0.07 ENSMUST00000038539.6
RIKEN cDNA 1700123O20 gene
chr5_-_135744206 0.06 ENSMUST00000153399.1
ENSMUST00000043378.2
transmembrane protein 120A
chr18_+_65582239 0.05 ENSMUST00000182684.1
zinc finger protein 532
chr3_+_95658771 0.05 ENSMUST00000178686.1
myeloid cell leukemia sequence 1
chr1_+_109993982 0.05 ENSMUST00000027542.6
cadherin 7, type 2
chr8_+_94386486 0.05 ENSMUST00000034220.7
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
chr6_+_17491216 0.05 ENSMUST00000080469.5
met proto-oncogene
chr8_+_94386438 0.05 ENSMUST00000161576.1
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
chrX_+_96455359 0.03 ENSMUST00000033553.7
hephaestin
chr5_+_90460889 0.01 ENSMUST00000031314.8
albumin

Network of associatons between targets according to the STRING database.

First level regulatory network of Cdx2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.1 GO:0001692 histamine metabolic process(GO:0001692) imidazole-containing compound catabolic process(GO:0052805)
0.2 0.8 GO:0090126 protein complex assembly involved in synapse maturation(GO:0090126)
0.2 0.5 GO:0070488 neutrophil aggregation(GO:0070488)
0.1 0.5 GO:0015827 aromatic amino acid transport(GO:0015801) tryptophan transport(GO:0015827)
0.1 0.6 GO:0035022 positive regulation of Rac protein signal transduction(GO:0035022)
0.1 1.3 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.1 0.5 GO:0021615 glossopharyngeal nerve morphogenesis(GO:0021615)
0.1 0.5 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.1 1.1 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.3 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.0 0.5 GO:0010839 negative regulation of keratinocyte proliferation(GO:0010839)
0.0 0.1 GO:0046368 GDP-L-fucose metabolic process(GO:0046368)
0.0 0.1 GO:1902256 endocardial cushion fusion(GO:0003274) apoptotic process involved in outflow tract morphogenesis(GO:0003275) positive regulation of integrin biosynthetic process(GO:0045726) regulation of catagen(GO:0051794) regulation of apoptotic process involved in outflow tract morphogenesis(GO:1902256)
0.0 0.1 GO:0021555 midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.0 0.1 GO:1903071 positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.0 0.1 GO:0021912 regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification(GO:0021912)
0.0 0.3 GO:0015937 coenzyme A biosynthetic process(GO:0015937)
0.0 0.2 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.3 GO:0045109 intermediate filament organization(GO:0045109)
0.0 0.1 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.1 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.1 1.3 GO:0045179 apical cortex(GO:0045179)
0.0 0.8 GO:0036057 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.1 GO:1990037 Lewy body core(GO:1990037)
0.0 0.4 GO:0045095 keratin filament(GO:0045095)
0.0 0.4 GO:0043194 axon initial segment(GO:0043194)
0.0 0.1 GO:0001739 sex chromatin(GO:0001739)
0.0 0.2 GO:0042581 specific granule(GO:0042581)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.3 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.1 0.5 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.1 0.6 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.1 0.8 GO:0097109 neuroligin family protein binding(GO:0097109)
0.1 0.5 GO:0035662 Toll-like receptor 4 binding(GO:0035662) RAGE receptor binding(GO:0050786)
0.1 0.6 GO:0019871 sodium channel inhibitor activity(GO:0019871)
0.1 0.3 GO:0004594 pantothenate kinase activity(GO:0004594)
0.0 0.7 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 1.3 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.1 GO:0030280 structural constituent of epidermis(GO:0030280)
0.0 0.2 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.1 GO:0034714 type III transforming growth factor beta receptor binding(GO:0034714)
0.0 1.1 GO:0008170 N-methyltransferase activity(GO:0008170)
0.0 0.0 GO:0005008 hepatocyte growth factor-activated receptor activity(GO:0005008)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 0.5 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.7 NABA PROTEOGLYCANS Genes encoding proteoglycans

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF CAMKII Genes involved in CREB phosphorylation through the activation of CaMKII
0.0 0.3 REACTOME VITAMIN B5 PANTOTHENATE METABOLISM Genes involved in Vitamin B5 (pantothenate) metabolism
0.0 0.4 REACTOME REGULATION OF GENE EXPRESSION IN BETA CELLS Genes involved in Regulation of gene expression in beta cells