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2D miR_HR1_12

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Results for Hbp1

Z-value: 1.08

Motif logo

Transcription factors associated with Hbp1

Gene Symbol Gene ID Gene Info
ENSMUSG00000002996.11 high mobility group box transcription factor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Hbp1mm10_v2_chr12_-_31950170_31950197-0.623.0e-02Click!

Activity profile of Hbp1 motif

Sorted Z-values of Hbp1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr6_+_78405148 1.75 ENSMUST00000023906.2
regenerating islet-derived 2
chr3_+_138277489 1.72 ENSMUST00000004232.9
alcohol dehydrogenase 1 (class I)
chr11_+_114727384 1.39 ENSMUST00000069325.7
dynein, axonemal, intermediate chain 2
chr6_-_41035501 1.23 ENSMUST00000031931.5
RIKEN cDNA 2210010C04 gene
chr3_-_113574758 1.22 ENSMUST00000106540.1
amylase 1, salivary
chr3_-_113532288 1.21 ENSMUST00000132353.1
amylase 2a1
chr12_-_20900867 1.17 ENSMUST00000079237.5
zinc finger protein 125
chr3_-_113258837 1.13 ENSMUST00000098673.3
amylase 2a5
chr10_-_81291227 1.12 ENSMUST00000045744.6
tight junction protein 3
chr1_-_184033998 1.12 ENSMUST00000050306.5
RIKEN cDNA 1700056E22 gene
chr7_-_131322292 1.10 ENSMUST00000046611.7
CUB and zona pellucida-like domains 1
chr12_-_84698769 1.10 ENSMUST00000095550.2
synapse differentiation inducing 1 like
chr15_+_16778101 1.08 ENSMUST00000026432.6
cadherin 9
chr3_-_113324052 1.07 ENSMUST00000179314.1
amylase 2a3
chrX_+_164438039 1.05 ENSMUST00000033755.5
ankyrin repeat and SOCS box-containing 11
chr10_+_127898515 1.02 ENSMUST00000047134.7
4short chain dehydrogenase/reductase family 9C, member 7
chr6_-_41446062 1.02 ENSMUST00000095999.5
predicted gene 10334
chr5_+_115466234 0.99 ENSMUST00000145785.1
ENSMUST00000031495.4
ENSMUST00000112071.1
ENSMUST00000125568.1
phospholipase A2, group IB, pancreas
chr7_+_44207307 0.96 ENSMUST00000077354.4
kallikrein 1-related pepidase b4
chr1_-_158814469 0.95 ENSMUST00000161589.2
pappalysin 2
chr5_-_86906937 0.93 ENSMUST00000031181.9
ENSMUST00000113333.1
UDP glucuronosyltransferase 2 family, polypeptide B34
chr8_-_123754138 0.93 ENSMUST00000181805.1
RIKEN cDNA 4732419C18 gene
chr3_-_113291449 0.93 ENSMUST00000179568.1
amylase 2a4
chr6_+_41392356 0.90 ENSMUST00000049079.7
predicted gene 5771
chr16_+_31878810 0.88 ENSMUST00000023464.5
antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5
chr18_-_43737186 0.82 ENSMUST00000025381.2
serine peptidase inhibitor, Kazal type 3
chr6_-_41377604 0.79 ENSMUST00000096003.5
protease, serine, 3
chr4_-_130279205 0.78 ENSMUST00000120126.2
serine incorporator 2
chr6_+_139843648 0.75 ENSMUST00000087657.6
phosphatidylinositol 3-kinase, C2 domain containing, gamma polypeptide
chrX_-_169187200 0.75 ENSMUST00000066112.5
ENSMUST00000112118.1
ENSMUST00000112120.1
ENSMUST00000112119.1
amelogenin, X-linked
chr6_-_82774448 0.74 ENSMUST00000000642.4
hexokinase 2
chr1_+_88070765 0.74 ENSMUST00000073772.4
UDP glucuronosyltransferase 1 family, polypeptide A9
chr5_-_70842617 0.73 ENSMUST00000031119.1
gamma-aminobutyric acid (GABA) A receptor, subunit gamma 1
chr4_-_129057957 0.73 ENSMUST00000149472.2
RIKEN cDNA 1700086P04 gene
chr5_+_135994796 0.72 ENSMUST00000111142.2
ENSMUST00000111145.3
ENSMUST00000111144.1
ENSMUST00000005072.3
ENSMUST00000130345.1
deltex 2 homolog (Drosophila)
chr7_-_30450864 0.71 ENSMUST00000170152.1
kin of IRRE like 2 (Drosophila)
chr11_+_68556186 0.71 ENSMUST00000053211.6
major facilitator superfamily domain containing 6-like
chr1_-_91459254 0.71 ENSMUST00000069620.8
period circadian clock 2
chr2_-_62483637 0.69 ENSMUST00000136686.1
ENSMUST00000102733.3
glucagon
chr7_-_19676749 0.68 ENSMUST00000003074.9
apolipoprotein C-II
chr17_+_17402672 0.67 ENSMUST00000115576.2
limb expression 1 homolog (chicken)
chr6_-_71144338 0.66 ENSMUST00000074241.7
ENSMUST00000160918.1
threonine synthase-like 2 (bacterial)
chr14_-_30943275 0.66 ENSMUST00000006704.8
ENSMUST00000163118.1
inter-alpha trypsin inhibitor, heavy chain 1
chr11_+_115887601 0.63 ENSMUST00000167507.2
myosin XVB
chr6_+_41302265 0.62 ENSMUST00000031913.4
trypsin 4
chr4_-_62519885 0.62 ENSMUST00000107444.1
ENSMUST00000030090.3
aminolevulinate, delta-, dehydratase
chr1_+_21240581 0.61 ENSMUST00000027067.8
glutathione S-transferase, alpha 3
chr1_+_88138364 0.61 ENSMUST00000014263.4
UDP glucuronosyltransferase 1 family, polypeptide A6A
chr3_-_85722474 0.60 ENSMUST00000119077.1
family with sequence similarity 160, member A1
chr9_+_21955747 0.60 ENSMUST00000053583.5
SWIM type zinc finger 7 associated protein 1
chr5_-_123865491 0.59 ENSMUST00000057145.5
niacin receptor 1
chr18_+_82855894 0.58 ENSMUST00000181345.1
ENSMUST00000180631.1
RIKEN cDNA 4930445N18 gene
chr9_-_96862903 0.56 ENSMUST00000121077.1
ENSMUST00000124923.1
acid phosphatase-like 2
chr1_+_88211956 0.56 ENSMUST00000073049.6
UDP glucuronosyltransferase 1 family, polypeptide A1
chr10_+_57784859 0.56 ENSMUST00000020024.5
fatty acid binding protein 7, brain
chr8_+_119666498 0.56 ENSMUST00000024107.5
WAP four-disulfide core domain 1
chr11_-_58330319 0.55 ENSMUST00000065533.2
predicted gene 9900
chr3_-_88296838 0.54 ENSMUST00000010682.3
TSSK6 activating co-chaperone
chr16_+_32756336 0.54 ENSMUST00000135753.1
mucin 4
chr12_-_23780265 0.54 ENSMUST00000072014.4
predicted gene 10330
chr19_+_38481057 0.53 ENSMUST00000182481.1
phospholipase C, epsilon 1
chr18_-_35215008 0.53 ENSMUST00000091636.3
leucine rich repeat transmembrane neuronal 2
chr1_+_21240597 0.53 ENSMUST00000121676.1
glutathione S-transferase, alpha 3
chr11_-_99493112 0.52 ENSMUST00000006969.7
keratin 23
chr3_-_106167564 0.51 ENSMUST00000063062.8
chitinase 3-like 3
chr1_+_184034381 0.51 ENSMUST00000048655.7
dual specificity phosphatase 10
chr11_+_81860679 0.51 ENSMUST00000021044.3
RIKEN cDNA 5530401A14 gene
chr18_-_36726730 0.51 ENSMUST00000061829.6
CD14 antigen
chr1_+_88055377 0.50 ENSMUST00000138182.1
ENSMUST00000113142.3
UDP glycosyltransferase 1 family, polypeptide A10
chr17_-_31636631 0.50 ENSMUST00000135425.1
ENSMUST00000151718.1
ENSMUST00000155814.1
cystathionine beta-synthase
chr6_+_145145473 0.50 ENSMUST00000156849.1
ENSMUST00000132948.1
lymphoid-restricted membrane protein
chr11_+_83709015 0.49 ENSMUST00000001009.7
WAP four-disulfide core domain 18
chr12_-_119238794 0.49 ENSMUST00000026360.8
integrin beta 8
chr8_+_119992438 0.48 ENSMUST00000132583.1
ENSMUST00000034282.9
cysteine-rich secretory protein LCCL domain containing 2
chr10_+_81633694 0.47 ENSMUST00000140345.1
ENSMUST00000126323.1
ankyrin repeat domain 24
chr4_-_42034726 0.47 ENSMUST00000084677.2
predicted gene, 21093
chr18_+_59062462 0.47 ENSMUST00000058633.2
ENSMUST00000175897.1
ENSMUST00000118510.1
ENSMUST00000175830.1
RIKEN cDNA A730017C20 gene
chr17_-_63863791 0.47 ENSMUST00000050753.3
RIKEN cDNA A930002H24 gene
chr13_-_113046357 0.46 ENSMUST00000022282.3
glutathione peroxidase 8 (putative)
chr5_+_90367204 0.45 ENSMUST00000068250.3
predicted gene 9958
chr10_+_128270546 0.45 ENSMUST00000105238.3
ENSMUST00000085708.2
signal transducer and activator of transcription 2
chr7_-_19677941 0.45 ENSMUST00000142352.1
apolipoprotein C-II
chr16_-_97170707 0.45 ENSMUST00000056102.7
Down syndrome cell adhesion molecule
chr6_-_29179584 0.44 ENSMUST00000159200.1
proline-rich transmembrane protein 4
chr3_+_60031754 0.44 ENSMUST00000029325.3
arylacetamide deacetylase (esterase)
chr11_+_101246960 0.44 ENSMUST00000107282.3
receptor (calcitonin) activity modifying protein 2
chr5_+_135168283 0.44 ENSMUST00000031692.5
B cell CLL/lymphoma 7B
chr1_-_135375233 0.44 ENSMUST00000041240.3
shisa homolog 4 (Xenopus laevis)
chr5_-_37336870 0.43 ENSMUST00000031005.4
Ellis van Creveld gene syndrome
chr5_+_90561102 0.43 ENSMUST00000094615.4
RIKEN cDNA 5830473C10 gene
chr8_+_72319033 0.43 ENSMUST00000067912.7
Kruppel-like factor 2 (lung)
chr5_+_90772435 0.43 ENSMUST00000031320.6
platelet factor 4
chr12_-_84773087 0.43 ENSMUST00000021668.8
Niemann Pick type C2
chr4_-_94928820 0.43 ENSMUST00000107097.2
equatorin, sperm acrosome associated
chr17_-_29549588 0.43 ENSMUST00000114683.2
ENSMUST00000168339.1
transmembrane protein 217
chr1_-_20617992 0.43 ENSMUST00000088448.5
polycystic kidney and hepatic disease 1
chr2_+_152143552 0.42 ENSMUST00000089112.5
transcription factor 15
chr16_+_4639941 0.41 ENSMUST00000038770.3
vasorin
chr10_+_81628570 0.41 ENSMUST00000153573.1
ENSMUST00000119336.1
ankyrin repeat domain 24
chr2_-_25501717 0.40 ENSMUST00000015227.3
complement component 8, gamma polypeptide
chr1_+_88095054 0.40 ENSMUST00000150634.1
ENSMUST00000058237.7
UDP glucuronosyltransferase 1 family, polypeptide A7C
chr6_+_100704709 0.40 ENSMUST00000032157.7
glucoside xylosyltransferase 2
chr5_+_135168382 0.40 ENSMUST00000111187.3
ENSMUST00000111188.1
B cell CLL/lymphoma 7B
chr7_-_25297866 0.40 ENSMUST00000148150.1
ENSMUST00000155118.1
platelet-activating factor acetylhydrolase, isoform 1b, subunit 3
chr13_-_92131494 0.40 ENSMUST00000099326.3
ENSMUST00000146492.1
RAS protein-specific guanine nucleotide-releasing factor 2
chr14_+_55561060 0.39 ENSMUST00000117701.1
DDB1 and CUL4 associated factor 11
chr12_+_109549157 0.39 ENSMUST00000128458.1
ENSMUST00000150851.1
maternally expressed 3
chr12_-_104153846 0.39 ENSMUST00000085050.3
serine (or cysteine) peptidase inhibitor, clade A, member 3C
chr7_+_128129536 0.38 ENSMUST00000033053.6
integrin alpha X
chr11_+_46404720 0.38 ENSMUST00000063166.5
family with sequence similarity 71, member B
chr6_-_72362382 0.38 ENSMUST00000114095.1
ENSMUST00000069595.6
ENSMUST00000069580.5
ring finger protein 181
chr5_-_137921612 0.38 ENSMUST00000031741.7
cytochrome P450, family 3, subfamily a, polypeptide 13
chr4_-_42661893 0.37 ENSMUST00000108006.3
interleukin 11 receptor, alpha chain 2
chr1_-_13127163 0.37 ENSMUST00000047577.6
PR domain containing 14
chrX_-_51205990 0.37 ENSMUST00000114876.2
muscleblind-like 3 (Drosophila)
chr19_+_53529100 0.37 ENSMUST00000038287.6
dual specificity phosphatase 5
chr7_+_118633729 0.37 ENSMUST00000057320.7
transmembrane channel-like gene family 5
chr10_+_57784914 0.37 ENSMUST00000165013.1
fatty acid binding protein 7, brain
chr9_+_74861888 0.37 ENSMUST00000056006.9
one cut domain, family member 1
chr13_-_114932035 0.36 ENSMUST00000056117.8
integrin alpha 2
chr15_-_36879816 0.36 ENSMUST00000100713.2
predicted gene 10384
chr9_+_75232013 0.36 ENSMUST00000036555.6
myosin VC
chr19_+_47937648 0.36 ENSMUST00000066308.7
coiled-coil domain containing 147
chr17_-_14934653 0.36 ENSMUST00000170386.1
WD repeat domain 27
chr8_-_8639363 0.35 ENSMUST00000152698.1
ephrin B2
chr9_-_106891965 0.35 ENSMUST00000159283.1
mesencephalic astrocyte-derived neurotrophic factor
chr17_+_29549783 0.34 ENSMUST00000048677.7
TBC1 domain family, member 22B
chr10_+_80167778 0.34 ENSMUST00000105365.2
ENSMUST00000054666.6
cold inducible RNA binding protein
chr7_-_25297967 0.34 ENSMUST00000005583.5
platelet-activating factor acetylhydrolase, isoform 1b, subunit 3
chr6_-_85762480 0.34 ENSMUST00000168531.1
camello-like 3
chr18_+_37484955 0.34 ENSMUST00000053856.4
protocadherin beta 17
chr3_+_106721672 0.34 ENSMUST00000098750.2
ENSMUST00000130105.1
ligand dependent nuclear receptor interacting factor 1
chr17_-_85090204 0.34 ENSMUST00000072406.3
ENSMUST00000171795.1
prolyl endopeptidase-like
chr11_-_99244058 0.33 ENSMUST00000103132.3
ENSMUST00000038214.6
keratin 222
chr9_+_57697612 0.33 ENSMUST00000034865.4
cytochrome P450, family 1, subfamily a, polypeptide 1
chr6_+_122308684 0.33 ENSMUST00000007602.8
ENSMUST00000112610.1
mannose-6-phosphate receptor, cation dependent
chr15_+_84232030 0.33 ENSMUST00000023072.6
parvin, beta
chrX_+_159840463 0.33 ENSMUST00000112451.1
ENSMUST00000112453.2
SH3-domain kinase binding protein 1
chr5_-_135573036 0.33 ENSMUST00000004936.6
chemokine (C-C motif) ligand 24
chr9_-_106891870 0.32 ENSMUST00000160503.1
ENSMUST00000159620.2
ENSMUST00000160978.1
mesencephalic astrocyte-derived neurotrophic factor
chr4_-_130275523 0.32 ENSMUST00000146478.1
serine incorporator 2
chr8_+_71689214 0.32 ENSMUST00000034261.7
insulin-like 3
chr11_+_70540260 0.32 ENSMUST00000018429.5
ENSMUST00000108557.3
ENSMUST00000108556.1
phospholipase D2
chr8_+_94810446 0.32 ENSMUST00000034232.1
chemokine (C-C motif) ligand 17
chr19_+_3851797 0.32 ENSMUST00000072055.6
choline kinase alpha
chr11_-_11462408 0.32 ENSMUST00000020413.3
zona pellucida binding protein
chr1_+_88200601 0.31 ENSMUST00000049289.8
UDP glucuronosyltransferase 1 family, polypeptide A2
chr3_+_90537306 0.31 ENSMUST00000107335.1
S100 calcium binding protein A16
chr1_+_40681659 0.31 ENSMUST00000027231.7
solute carrier family 9 (sodium/hydrogen exchanger), member 2
chr11_+_5520652 0.31 ENSMUST00000063084.9
X-box binding protein 1
chr10_-_81037300 0.30 ENSMUST00000059551.4
ENSMUST00000117276.2
solute carrier family 39 (zinc transporter), member 3
chr5_-_87140318 0.30 ENSMUST00000067790.6
ENSMUST00000113327.1
UDP glucuronosyltransferase 2 family, polypeptide B5
chr8_-_86580664 0.30 ENSMUST00000131423.1
ENSMUST00000152438.1
ATP-binding cassette, sub-family C (CFTR/MRP), member 12
chr1_+_88055467 0.30 ENSMUST00000173325.1
UDP glycosyltransferase 1 family, polypeptide A10
chr10_+_73821937 0.30 ENSMUST00000134009.2
ENSMUST00000125006.2
ENSMUST00000177420.1
protocadherin 15
chr11_+_95009852 0.30 ENSMUST00000055947.3
sterile alpha motif domain containing 14
chrX_-_95658416 0.30 ENSMUST00000044382.6
zinc finger, C4H2 domain containing
chr17_-_34862473 0.29 ENSMUST00000025229.4
ENSMUST00000176203.2
ENSMUST00000128767.1
complement factor B
chr11_+_17211912 0.29 ENSMUST00000046955.6
WD repeat domain 92
chr17_+_8924109 0.29 ENSMUST00000149440.1
phosphodiesterase 10A
chr19_-_43986552 0.29 ENSMUST00000026210.4
carboxypeptidase N, polypeptide 1
chr2_+_136891501 0.29 ENSMUST00000141463.1
SLX4 interacting protein
chr3_+_106113229 0.29 ENSMUST00000079132.5
ENSMUST00000139086.1
chitinase, acidic
chr9_+_109931774 0.28 ENSMUST00000169851.2
microtubule-associated protein 4
chr2_-_5063932 0.28 ENSMUST00000027986.4
optineurin
chr8_-_70139197 0.28 ENSMUST00000075724.7
regulatory factor X-associated ankyrin-containing protein
chr4_-_57301475 0.28 ENSMUST00000130900.1
protein tyrosine phosphatase, non-receptor type 3
chr13_-_51701041 0.28 ENSMUST00000110042.1
predicted gene 15440
chr1_+_32172711 0.28 ENSMUST00000027226.5
KH domain containing, RNA binding, signal transduction associated 2
chr3_+_90537242 0.28 ENSMUST00000098911.3
S100 calcium binding protein A16
chrX_-_95658392 0.28 ENSMUST00000120620.1
zinc finger, C4H2 domain containing
chr16_-_10543028 0.28 ENSMUST00000184863.1
ENSMUST00000038281.5
dexamethasone-induced transcript
chr11_-_120713725 0.28 ENSMUST00000106154.1
ENSMUST00000106155.3
ENSMUST00000055424.6
ENSMUST00000026137.7
stimulated by retinoic acid 13
chr5_-_100373484 0.28 ENSMUST00000182433.1
Sec31 homolog A (S. cerevisiae)
chr16_+_33062512 0.27 ENSMUST00000023497.2
leishmanolysin-like (metallopeptidase M8 family)
chr15_+_97247011 0.27 ENSMUST00000059433.6
PC-esterase domain containing 1B
chr6_-_131316398 0.27 ENSMUST00000121078.1
serine/threonine/tyrosine kinase 1
chr19_-_4498574 0.27 ENSMUST00000048482.6
RIKEN cDNA 2010003K11 gene
chr1_-_45503282 0.27 ENSMUST00000086430.4
collagen, type V, alpha 2
chr3_-_79145875 0.27 ENSMUST00000118340.1
Rap guanine nucleotide exchange factor (GEF) 2
chr17_+_21691860 0.27 ENSMUST00000072133.4
predicted gene 10226
chr5_+_90518932 0.27 ENSMUST00000113179.2
ENSMUST00000128740.1
afamin
chr2_-_140066661 0.26 ENSMUST00000046656.2
ENSMUST00000099304.3
ENSMUST00000110079.2
taspase, threonine aspartase 1
chr11_+_26387194 0.26 ENSMUST00000109509.1
ENSMUST00000136830.1
Fanconi anemia, complementation group L
chr5_+_19907502 0.26 ENSMUST00000101558.3
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr7_-_139582790 0.26 ENSMUST00000106095.2
NK6 homeobox 2
chr11_+_4186789 0.26 ENSMUST00000041042.6
ENSMUST00000180088.1
TBC1 domain family, member 10a
chr18_-_38866702 0.26 ENSMUST00000115582.1
fibroblast growth factor 1
chr17_-_63499983 0.26 ENSMUST00000024761.6
F-box and leucine-rich repeat protein 17
chr17_+_25471564 0.26 ENSMUST00000025002.1
tektin 4
chr17_+_48247759 0.26 ENSMUST00000048065.5
triggering receptor expressed on myeloid cells 3
chr18_+_37320374 0.25 ENSMUST00000078271.2
protocadherin beta 5
chrX_-_7572843 0.25 ENSMUST00000132788.1
protein phosphatase 1, regulatory (inhibitor) subunit 3F
chr11_-_120549695 0.25 ENSMUST00000034913.4
family with sequence similarity 195, member B
chr11_+_120673018 0.25 ENSMUST00000106158.2
ENSMUST00000103016.1
ENSMUST00000168714.1
alveolar soft part sarcoma chromosome region, candidate 1 (human)
chr11_-_49114874 0.25 ENSMUST00000109201.1
olfactory receptor 1396
chrX_+_6047453 0.25 ENSMUST00000103007.3
nudix (nucleoside diphosphate linked moiety X)-type motif 11
chr1_+_174501796 0.25 ENSMUST00000030039.7
formin 2
chr3_-_87748619 0.25 ENSMUST00000023846.4
leucine rich repeat containing 71
chr11_-_120731944 0.25 ENSMUST00000154565.1
ENSMUST00000026148.2
carbonyl reductase 2

Network of associatons between targets according to the STRING database.

First level regulatory network of Hbp1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.7 GO:0006069 ethanol oxidation(GO:0006069)
0.4 1.1 GO:0043387 mycotoxin metabolic process(GO:0043385) mycotoxin catabolic process(GO:0043387) aflatoxin metabolic process(GO:0046222) aflatoxin catabolic process(GO:0046223) organic heteropentacyclic compound metabolic process(GO:1901376) organic heteropentacyclic compound catabolic process(GO:1901377)
0.3 1.0 GO:0044240 multicellular organism lipid catabolic process(GO:0044240)
0.3 3.7 GO:0052696 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.2 0.7 GO:0031554 regulation of DNA-templated transcription, termination(GO:0031554)
0.2 1.1 GO:0060697 positive regulation of phospholipid catabolic process(GO:0060697)
0.2 0.7 GO:0002014 vasoconstriction of artery involved in ischemic response to lowering of systemic arterial blood pressure(GO:0002014)
0.2 0.5 GO:0071725 response to triacyl bacterial lipopeptide(GO:0071725) cellular response to triacyl bacterial lipopeptide(GO:0071727)
0.2 0.3 GO:0009804 coumarin metabolic process(GO:0009804)
0.2 0.5 GO:0019343 cysteine biosynthetic process via cystathionine(GO:0019343)
0.2 0.7 GO:0006566 threonine metabolic process(GO:0006566)
0.2 0.7 GO:1902093 positive regulation of sperm motility(GO:1902093)
0.2 1.1 GO:1904217 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.1 0.4 GO:0060060 post-embryonic retina morphogenesis in camera-type eye(GO:0060060)
0.1 0.7 GO:1904925 positive regulation of macromitophagy(GO:1901526) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925)
0.1 0.7 GO:0071499 response to laminar fluid shear stress(GO:0034616) cellular response to laminar fluid shear stress(GO:0071499)
0.1 0.4 GO:2001188 negative regulation of immunological synapse formation(GO:2000521) regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001188) negative regulation of T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:2001189)
0.1 0.5 GO:0002835 negative regulation of response to tumor cell(GO:0002835) negative regulation of immune response to tumor cell(GO:0002838)
0.1 0.4 GO:0002355 detection of tumor cell(GO:0002355)
0.1 0.4 GO:0080154 regulation of fertilization(GO:0080154)
0.1 0.3 GO:0071963 establishment or maintenance of cell polarity regulating cell shape(GO:0071963)
0.1 0.3 GO:2000418 positive regulation of eosinophil migration(GO:2000418)
0.1 0.3 GO:1903406 regulation of sodium:potassium-exchanging ATPase activity(GO:1903406)
0.1 0.3 GO:0050973 detection of mechanical stimulus involved in equilibrioception(GO:0050973)
0.1 0.7 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.1 0.4 GO:0009816 defense response to bacterium, incompatible interaction(GO:0009816) regulation of defense response to bacterium, incompatible interaction(GO:1902477)
0.1 1.4 GO:0036158 outer dynein arm assembly(GO:0036158)
0.1 0.3 GO:2000670 positive regulation of dendritic cell apoptotic process(GO:2000670)
0.1 0.4 GO:0045347 negative regulation of MHC class II biosynthetic process(GO:0045347)
0.1 0.4 GO:0060478 acrosomal vesicle exocytosis(GO:0060478)
0.1 0.3 GO:0070649 meiotic chromosome movement towards spindle pole(GO:0016344) formin-nucleated actin cable assembly(GO:0070649)
0.1 1.1 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.1 0.2 GO:1904835 vestibulocochlear nerve structural organization(GO:0021649) ganglion morphogenesis(GO:0061552) dorsal root ganglion morphogenesis(GO:1904835)
0.1 0.6 GO:0019695 choline metabolic process(GO:0019695)
0.1 0.2 GO:0007521 muscle cell fate determination(GO:0007521)
0.1 1.7 GO:0001967 suckling behavior(GO:0001967)
0.1 0.2 GO:0090264 immune complex clearance by monocytes and macrophages(GO:0002436) astrocyte chemotaxis(GO:0035700) regulation of immune complex clearance by monocytes and macrophages(GO:0090264) positive regulation of immune complex clearance by monocytes and macrophages(GO:0090265) negative regulation of eosinophil activation(GO:1902567) positive regulation of CD8-positive, alpha-beta T cell extravasation(GO:2000451) regulation of astrocyte chemotaxis(GO:2000458)
0.1 0.3 GO:0030070 insulin processing(GO:0030070)
0.1 0.5 GO:0060266 negative regulation of respiratory burst involved in inflammatory response(GO:0060266)
0.1 0.4 GO:0010694 positive regulation of alkaline phosphatase activity(GO:0010694)
0.1 0.4 GO:0051775 response to redox state(GO:0051775)
0.1 0.1 GO:0052695 cellular glucuronidation(GO:0052695)
0.1 0.2 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.1 0.3 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.1 0.4 GO:0010898 positive regulation of triglyceride catabolic process(GO:0010898)
0.1 0.6 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.1 0.2 GO:0046947 hydroxylysine metabolic process(GO:0046946) hydroxylysine biosynthetic process(GO:0046947)
0.1 0.2 GO:0090481 pyrimidine nucleotide-sugar transmembrane transport(GO:0090481)
0.1 0.3 GO:1903599 positive regulation of mitophagy(GO:1903599)
0.1 0.3 GO:0070417 cellular response to cold(GO:0070417)
0.1 0.4 GO:0016266 O-glycan processing(GO:0016266)
0.1 0.3 GO:1902856 negative regulation of nonmotile primary cilium assembly(GO:1902856)
0.1 0.3 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.1 0.2 GO:0044339 canonical Wnt signaling pathway involved in osteoblast differentiation(GO:0044339)
0.1 0.2 GO:0061402 glycerol biosynthetic process(GO:0006114) positive regulation of transcription from RNA polymerase II promoter in response to acidic pH(GO:0061402)
0.1 0.9 GO:0060134 prepulse inhibition(GO:0060134)
0.1 0.2 GO:0051697 protein delipidation(GO:0051697)
0.1 0.1 GO:0060369 positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369)
0.1 0.3 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.1 0.3 GO:1901509 regulation of endothelial tube morphogenesis(GO:1901509)
0.1 0.2 GO:0006481 C-terminal protein methylation(GO:0006481)
0.0 0.2 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.0 0.2 GO:0010940 positive regulation of necrotic cell death(GO:0010940)
0.0 0.1 GO:0044837 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.0 0.1 GO:0071799 response to prostaglandin D(GO:0071798) cellular response to prostaglandin D stimulus(GO:0071799)
0.0 0.3 GO:0009235 cobalamin metabolic process(GO:0009235)
0.0 0.2 GO:0060158 phospholipase C-activating dopamine receptor signaling pathway(GO:0060158)
0.0 0.3 GO:1903849 regulation of aorta morphogenesis(GO:1903847) positive regulation of aorta morphogenesis(GO:1903849)
0.0 0.1 GO:1905154 negative regulation of membrane invagination(GO:1905154)
0.0 0.3 GO:0070945 neutrophil mediated killing of gram-negative bacterium(GO:0070945)
0.0 0.2 GO:0097029 mature conventional dendritic cell differentiation(GO:0097029)
0.0 0.2 GO:0032789 saturated monocarboxylic acid metabolic process(GO:0032788) unsaturated monocarboxylic acid metabolic process(GO:0032789)
0.0 0.3 GO:1901908 diphosphoinositol polyphosphate metabolic process(GO:0071543) diadenosine pentaphosphate metabolic process(GO:1901906) diadenosine pentaphosphate catabolic process(GO:1901907) diadenosine hexaphosphate metabolic process(GO:1901908) diadenosine hexaphosphate catabolic process(GO:1901909) adenosine 5'-(hexahydrogen pentaphosphate) metabolic process(GO:1901910) adenosine 5'-(hexahydrogen pentaphosphate) catabolic process(GO:1901911)
0.0 0.3 GO:0006116 NADH oxidation(GO:0006116)
0.0 0.4 GO:0045198 establishment of epithelial cell apical/basal polarity(GO:0045198)
0.0 0.2 GO:0044375 regulation of peroxisome size(GO:0044375)
0.0 0.2 GO:0051919 positive regulation of fibrinolysis(GO:0051919)
0.0 0.2 GO:0034124 regulation of MyD88-dependent toll-like receptor signaling pathway(GO:0034124)
0.0 0.2 GO:0050957 equilibrioception(GO:0050957)
0.0 0.1 GO:0021558 trochlear nerve development(GO:0021558)
0.0 0.3 GO:0048853 forebrain morphogenesis(GO:0048853)
0.0 0.3 GO:0021912 regulation of transcription from RNA polymerase II promoter involved in spinal cord motor neuron fate specification(GO:0021912)
0.0 0.4 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.0 0.1 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.0 0.1 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.0 0.7 GO:0034505 tooth mineralization(GO:0034505)
0.0 0.2 GO:0010796 regulation of multivesicular body size(GO:0010796)
0.0 0.1 GO:2000843 testosterone secretion(GO:0035936) positive regulation of apoptotic DNA fragmentation(GO:1902512) negative regulation of steroid hormone secretion(GO:2000832) regulation of testosterone secretion(GO:2000843)
0.0 1.0 GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
0.0 0.2 GO:0006363 termination of RNA polymerase I transcription(GO:0006363)
0.0 0.2 GO:0019532 oxalate transport(GO:0019532)
0.0 0.8 GO:0039694 viral RNA genome replication(GO:0039694) RNA replication(GO:0039703)
0.0 0.2 GO:0043097 pyrimidine-containing compound salvage(GO:0008655) pyrimidine nucleoside salvage(GO:0043097)
0.0 0.2 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.0 0.2 GO:1903224 regulation of endodermal cell fate specification(GO:0042663) regulation of endodermal cell differentiation(GO:1903224)
0.0 0.1 GO:1902256 apoptotic process involved in outflow tract morphogenesis(GO:0003275) negative regulation of lymphangiogenesis(GO:1901491) regulation of apoptotic process involved in outflow tract morphogenesis(GO:1902256) response to chemokine(GO:1990868) cellular response to chemokine(GO:1990869)
0.0 0.4 GO:0033327 Leydig cell differentiation(GO:0033327)
0.0 0.1 GO:0002276 basophil activation involved in immune response(GO:0002276)
0.0 0.3 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0 0.3 GO:0033299 secretion of lysosomal enzymes(GO:0033299)
0.0 0.2 GO:0000042 protein targeting to Golgi(GO:0000042)
0.0 0.1 GO:2001025 positive regulation of anion channel activity(GO:1901529) positive regulation of response to drug(GO:2001025)
0.0 0.3 GO:2000018 regulation of male gonad development(GO:2000018)
0.0 0.1 GO:1904566 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.0 0.4 GO:0032366 intracellular sterol transport(GO:0032366) intracellular cholesterol transport(GO:0032367)
0.0 0.3 GO:0006968 cellular defense response(GO:0006968)
0.0 0.4 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.1 GO:0014028 notochord formation(GO:0014028)
0.0 0.4 GO:2000310 regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310)
0.0 0.2 GO:1901386 negative regulation of voltage-gated calcium channel activity(GO:1901386)
0.0 3.2 GO:0007586 digestion(GO:0007586)
0.0 0.5 GO:0001573 ganglioside metabolic process(GO:0001573)
0.0 0.1 GO:0070672 response to interleukin-15(GO:0070672)
0.0 0.2 GO:1901727 positive regulation of histone deacetylase activity(GO:1901727)
0.0 0.2 GO:0042940 D-amino acid transport(GO:0042940)
0.0 0.4 GO:0043306 G-protein coupled receptor internalization(GO:0002031) positive regulation of mast cell activation involved in immune response(GO:0033008) positive regulation of mast cell degranulation(GO:0043306)
0.0 0.1 GO:0032918 polyamine acetylation(GO:0032917) spermidine acetylation(GO:0032918)
0.0 0.5 GO:0002091 negative regulation of receptor internalization(GO:0002091)
0.0 0.0 GO:0002901 mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906)
0.0 0.3 GO:2000465 regulation of glycogen (starch) synthase activity(GO:2000465)
0.0 0.2 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.0 0.1 GO:0043305 negative regulation of mast cell degranulation(GO:0043305)
0.0 0.6 GO:0046685 response to arsenic-containing substance(GO:0046685)
0.0 0.3 GO:1990118 sodium ion import across plasma membrane(GO:0098719) sodium ion import into cell(GO:1990118)
0.0 0.7 GO:0007214 gamma-aminobutyric acid signaling pathway(GO:0007214)
0.0 0.8 GO:0097352 autophagosome maturation(GO:0097352)
0.0 0.1 GO:0010966 regulation of phosphate transport(GO:0010966)
0.0 0.1 GO:0060066 oviduct development(GO:0060066)
0.0 0.2 GO:0043589 skin morphogenesis(GO:0043589)
0.0 0.1 GO:0016062 adaptation of rhodopsin mediated signaling(GO:0016062) light adaption(GO:0036367)
0.0 0.3 GO:0001675 acrosome assembly(GO:0001675)
0.0 0.3 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.1 GO:0009253 peptidoglycan metabolic process(GO:0000270) peptidoglycan catabolic process(GO:0009253)
0.0 0.2 GO:0019441 tryptophan catabolic process(GO:0006569) tryptophan catabolic process to kynurenine(GO:0019441) indole-containing compound catabolic process(GO:0042436) indolalkylamine catabolic process(GO:0046218) kynurenine metabolic process(GO:0070189)
0.0 0.1 GO:1903215 negative regulation of protein targeting to mitochondrion(GO:1903215)
0.0 0.6 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.0 0.1 GO:0071034 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.0 0.1 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.2 GO:0033006 regulation of mast cell activation involved in immune response(GO:0033006) regulation of mast cell degranulation(GO:0043304)
0.0 0.1 GO:0033189 response to vitamin A(GO:0033189)
0.0 0.1 GO:0035524 proline transmembrane transport(GO:0035524)
0.0 0.3 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.1 GO:0072656 maintenance of protein location in mitochondrion(GO:0072656)
0.0 0.2 GO:0042048 olfactory behavior(GO:0042048)
0.0 0.2 GO:0070423 nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway(GO:0035872) nucleotide-binding oligomerization domain containing signaling pathway(GO:0070423) nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070431)
0.0 0.1 GO:0038044 transforming growth factor-beta secretion(GO:0038044)
0.0 0.4 GO:0090140 regulation of mitochondrial fission(GO:0090140)
0.0 0.1 GO:0009446 spermidine biosynthetic process(GO:0008295) putrescine metabolic process(GO:0009445) putrescine biosynthetic process(GO:0009446)
0.0 0.1 GO:0035095 behavioral response to nicotine(GO:0035095)
0.0 0.2 GO:1904659 glucose transmembrane transport(GO:1904659)
0.0 0.1 GO:0051917 regulation of fibrinolysis(GO:0051917) negative regulation of fibrinolysis(GO:0051918)
0.0 0.4 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.0 0.2 GO:0007413 axonal fasciculation(GO:0007413)
0.0 0.1 GO:0042535 positive regulation of tumor necrosis factor biosynthetic process(GO:0042535)
0.0 0.4 GO:0051898 negative regulation of protein kinase B signaling(GO:0051898)
0.0 1.4 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.2 GO:0051026 chiasma assembly(GO:0051026)
0.0 0.1 GO:0070294 renal sodium ion transport(GO:0003096) renal sodium ion absorption(GO:0070294)
0.0 0.2 GO:0001771 immunological synapse formation(GO:0001771)
0.0 0.2 GO:0048387 negative regulation of retinoic acid receptor signaling pathway(GO:0048387)
0.0 0.2 GO:0006622 protein targeting to lysosome(GO:0006622)
0.0 0.1 GO:0071340 skeletal muscle acetylcholine-gated channel clustering(GO:0071340)
0.0 0.2 GO:1990845 adaptive thermogenesis(GO:1990845)
0.0 0.1 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.0 0.2 GO:0032252 secretory granule localization(GO:0032252)
0.0 0.1 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.0 0.2 GO:1903020 positive regulation of glycoprotein metabolic process(GO:1903020)
0.0 0.2 GO:0010884 positive regulation of lipid storage(GO:0010884)
0.0 0.6 GO:0061045 negative regulation of wound healing(GO:0061045)
0.0 0.1 GO:0019856 'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
0.0 0.5 GO:0034113 heterotypic cell-cell adhesion(GO:0034113)
0.0 0.1 GO:1900113 negative regulation of histone H3-K9 trimethylation(GO:1900113)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0002081 outer acrosomal membrane(GO:0002081)
0.1 0.4 GO:0034666 integrin alpha2-beta1 complex(GO:0034666)
0.1 1.4 GO:0036157 outer dynein arm(GO:0036157)
0.1 1.1 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.1 0.3 GO:0005588 collagen type V trimer(GO:0005588)
0.1 1.1 GO:0042589 zymogen granule membrane(GO:0042589)
0.1 0.2 GO:0005607 laminin-2 complex(GO:0005607)
0.1 0.4 GO:1903439 calcitonin family receptor complex(GO:1903439) amylin receptor complex(GO:1903440)
0.1 0.3 GO:1990037 Lewy body core(GO:1990037)
0.1 0.3 GO:0044194 cytolytic granule(GO:0044194)
0.1 0.5 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.1 1.0 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.1 0.2 GO:0005833 hemoglobin complex(GO:0005833)
0.1 0.4 GO:0005579 membrane attack complex(GO:0005579)
0.0 0.1 GO:0032783 ELL-EAF complex(GO:0032783)
0.0 0.6 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.1 GO:0034685 integrin alphav-beta6 complex(GO:0034685)
0.0 0.3 GO:0045098 type III intermediate filament(GO:0045098)
0.0 0.4 GO:0020005 symbiont-containing vacuole membrane(GO:0020005)
0.0 0.1 GO:1990730 VCP-NSFL1C complex(GO:1990730)
0.0 1.1 GO:0008305 integrin complex(GO:0008305)
0.0 0.1 GO:0044279 other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
0.0 0.7 GO:0005839 proteasome core complex(GO:0005839)
0.0 0.1 GO:0036019 endolysosome(GO:0036019)
0.0 0.5 GO:0031528 microvillus membrane(GO:0031528)
0.0 0.2 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.2 GO:0036128 CatSper complex(GO:0036128)
0.0 0.3 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.6 GO:0005942 phosphatidylinositol 3-kinase complex(GO:0005942)
0.0 0.2 GO:0001739 sex chromatin(GO:0001739)
0.0 0.3 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.4 GO:0097228 sperm principal piece(GO:0097228)
0.0 0.1 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 1.0 GO:0032420 stereocilium(GO:0032420)
0.0 0.1 GO:0042567 insulin-like growth factor ternary complex(GO:0042567)
0.0 0.3 GO:0005922 connexon complex(GO:0005922)
0.0 0.2 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 0.2 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.3 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.2 GO:0002199 zona pellucida receptor complex(GO:0002199)
0.0 0.1 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.0 0.7 GO:0034707 chloride channel complex(GO:0034707)
0.0 0.2 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.2 GO:0035253 ciliary rootlet(GO:0035253)
0.0 0.1 GO:0090543 Flemming body(GO:0090543)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 4.3 GO:0004556 alpha-amylase activity(GO:0004556)
0.6 1.7 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.4 1.1 GO:0060230 lipoprotein lipase activator activity(GO:0060230)
0.2 0.7 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.2 0.7 GO:0070905 serine binding(GO:0070905)
0.2 0.5 GO:0098809 nitrite reductase activity(GO:0098809)
0.1 0.7 GO:0046848 hydroxyapatite binding(GO:0046848)
0.1 4.9 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.1 0.5 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.1 0.5 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.1 1.0 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.1 0.9 GO:0008865 fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.1 0.4 GO:0045131 pre-mRNA branch point binding(GO:0045131)
0.1 0.3 GO:0031728 CCR3 chemokine receptor binding(GO:0031728)
0.1 0.4 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.1 0.3 GO:0008431 vitamin E binding(GO:0008431)
0.1 0.8 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.1 0.3 GO:2001069 glycogen binding(GO:2001069)
0.1 0.3 GO:0004104 cholinesterase activity(GO:0004104)
0.1 1.4 GO:0045504 dynein heavy chain binding(GO:0045504)
0.1 1.2 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.1 0.2 GO:0035717 chemokine (C-C motif) ligand 7 binding(GO:0035717)
0.1 0.6 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.1 0.2 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.1 0.4 GO:0097643 amylin receptor activity(GO:0097643)
0.1 0.4 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.1 1.1 GO:0070330 aromatase activity(GO:0070330)
0.1 0.5 GO:1990430 extracellular matrix protein binding(GO:1990430)
0.1 1.0 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.1 0.4 GO:0042285 UDP-xylosyltransferase activity(GO:0035252) xylosyltransferase activity(GO:0042285)
0.1 0.3 GO:0004090 carbonyl reductase (NADPH) activity(GO:0004090)
0.1 0.2 GO:0048030 disaccharide binding(GO:0048030)
0.1 0.2 GO:0008475 procollagen-lysine 5-dioxygenase activity(GO:0008475)
0.1 0.2 GO:0004974 leukotriene receptor activity(GO:0004974)
0.1 0.2 GO:0052870 tocopherol omega-hydroxylase activity(GO:0052870) alpha-tocopherol omega-hydroxylase activity(GO:0052871)
0.1 0.8 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.1 0.2 GO:0031720 haptoglobin binding(GO:0031720)
0.1 0.2 GO:0003880 protein C-terminal carboxyl O-methyltransferase activity(GO:0003880)
0.1 0.2 GO:0047961 glycine N-acyltransferase activity(GO:0047961)
0.0 0.1 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.0 0.5 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.7 GO:1990226 histone methyltransferase binding(GO:1990226)
0.0 0.2 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.0 0.2 GO:0008384 NF-kappaB-inducing kinase activity(GO:0004704) IkappaB kinase activity(GO:0008384)
0.0 0.1 GO:0050479 glyceryl-ether monooxygenase activity(GO:0050479)
0.0 0.3 GO:0008486 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.0 0.3 GO:0004118 cGMP-stimulated cyclic-nucleotide phosphodiesterase activity(GO:0004118)
0.0 0.2 GO:0004850 uridine phosphorylase activity(GO:0004850)
0.0 0.6 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.7 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.0 0.7 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.5 GO:0031697 beta-1 adrenergic receptor binding(GO:0031697)
0.0 6.3 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.3 GO:0031749 D2 dopamine receptor binding(GO:0031749)
0.0 0.1 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.0 0.5 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.3 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.2 GO:0001851 complement component C3b binding(GO:0001851)
0.0 0.1 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.0 0.2 GO:0005021 vascular endothelial growth factor-activated receptor activity(GO:0005021)
0.0 0.2 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 0.3 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.0 0.2 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.2 GO:0004849 uridine kinase activity(GO:0004849)
0.0 0.1 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.0 0.1 GO:0035651 AP-3 adaptor complex binding(GO:0035651)
0.0 0.2 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.2 GO:0008392 arachidonic acid epoxygenase activity(GO:0008392)
0.0 0.6 GO:0008266 poly(U) RNA binding(GO:0008266)
0.0 0.5 GO:0004435 phosphatidylinositol phospholipase C activity(GO:0004435)
0.0 0.2 GO:0051430 corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.0 0.2 GO:0050694 galactose 3-O-sulfotransferase activity(GO:0050694)
0.0 0.1 GO:0004145 diamine N-acetyltransferase activity(GO:0004145)
0.0 0.3 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.1 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.0 0.2 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 1.1 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.6 GO:0015149 hexose transmembrane transporter activity(GO:0015149)
0.0 0.1 GO:1904288 BAT3 complex binding(GO:1904288)
0.0 0.1 GO:0090554 phosphatidylcholine-translocating ATPase activity(GO:0090554)
0.0 0.1 GO:0060072 large conductance calcium-activated potassium channel activity(GO:0060072)
0.0 0.1 GO:0004088 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.0 2.0 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.1 GO:0004060 arylamine N-acetyltransferase activity(GO:0004060)
0.0 0.1 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.1 GO:0004794 L-threonine ammonia-lyase activity(GO:0004794)
0.0 1.0 GO:0005504 fatty acid binding(GO:0005504)
0.0 0.1 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.1 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 0.1 GO:0016167 glial cell-derived neurotrophic factor receptor activity(GO:0016167)
0.0 0.4 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 0.1 GO:0033691 sialic acid binding(GO:0033691)
0.0 0.4 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.2 GO:0030983 mismatched DNA binding(GO:0030983)
0.0 0.4 GO:0022829 wide pore channel activity(GO:0022829)
0.0 0.1 GO:0005223 intracellular cGMP activated cation channel activity(GO:0005223)
0.0 0.1 GO:0070492 oligosaccharide binding(GO:0070492)
0.0 0.3 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.0 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.0 0.2 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0 0.3 GO:0017171 serine hydrolase activity(GO:0017171)
0.0 0.1 GO:0035197 siRNA binding(GO:0035197)
0.0 0.7 GO:0030544 Hsp70 protein binding(GO:0030544)
0.0 0.2 GO:0001848 complement binding(GO:0001848)
0.0 0.1 GO:0042166 acetylcholine binding(GO:0042166)
0.0 0.1 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.2 GO:0016290 palmitoyl-CoA hydrolase activity(GO:0016290)
0.0 0.3 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.1 GO:0008508 bile acid:sodium symporter activity(GO:0008508)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 1.6 PID INTEGRIN CS PATHWAY Integrin family cell surface interactions
0.0 0.7 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.1 ST IL 13 PATHWAY Interleukin 13 (IL-13) Pathway
0.0 1.1 ST GA12 PATHWAY G alpha 12 Pathway
0.0 1.4 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.2 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 1.0 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.2 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 0.5 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.3 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.8 PID INTEGRIN1 PATHWAY Beta1 integrin cell surface interactions
0.0 0.7 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 0.6 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.5 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 0.2 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 0.9 PID FCER1 PATHWAY Fc-epsilon receptor I signaling in mast cells
0.0 0.4 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.0 0.2 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.2 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 1.1 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 2.6 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.2 PID EPHB FWD PATHWAY EPHB forward signaling
0.0 0.2 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.0 0.5 PID FGF PATHWAY FGF signaling pathway
0.0 0.3 PID BARD1 PATHWAY BARD1 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.5 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.1 0.3 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.1 1.1 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.1 1.1 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 1.1 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 0.7 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.6 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.8 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.0 0.7 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 1.4 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.2 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.0 0.4 REACTOME COMMON PATHWAY Genes involved in Common Pathway
0.0 0.7 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.3 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 1.0 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.0 0.6 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.8 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.4 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 1.0 REACTOME GLUTATHIONE CONJUGATION Genes involved in Glutathione conjugation
0.0 0.4 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.0 0.5 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.3 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.0 0.1 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.2 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.2 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.4 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.3 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 0.2 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.0 0.3 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.3 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 0.4 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.0 0.2 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 0.5 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.5 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.3 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.2 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.7 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.0 0.3 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.1 REACTOME PRESYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Presynaptic nicotinic acetylcholine receptors
0.0 0.2 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.7 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.1 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 0.2 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.3 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.5 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.1 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.3 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.2 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism