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2D miR_HR1_12

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Results for Nfix

Z-value: 0.66

Motif logo

Transcription factors associated with Nfix

Gene Symbol Gene ID Gene Info
ENSMUSG00000001911.10 nuclear factor I/X

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Nfixmm10_v2_chr8_-_84773381_847734270.491.0e-01Click!

Activity profile of Nfix motif

Sorted Z-values of Nfix motif

Promoter Log-likelihood Transcript Gene Gene Info
chr10_+_4611971 1.94 ENSMUST00000105590.1
ENSMUST00000067086.7
estrogen receptor 1 (alpha)
chr4_+_82065924 1.10 ENSMUST00000161588.1
predicted gene 5860
chr7_+_140763739 1.09 ENSMUST00000026552.7
cytochrome P450, family 2, subfamily e, polypeptide 1
chr2_+_130277157 0.93 ENSMUST00000028890.8
ENSMUST00000159373.1
NOP56 ribonucleoprotein
chr15_+_62178175 0.68 ENSMUST00000182476.1
plasmacytoma variant translocation 1
chr1_+_87594545 0.63 ENSMUST00000165109.1
ENSMUST00000070898.5
neuraminidase 2
chr7_-_97417730 0.61 ENSMUST00000043077.7
thyroid hormone responsive
chr1_-_192855723 0.61 ENSMUST00000155579.1
SERTA domain containing 4
chr16_-_55895279 0.57 ENSMUST00000099705.3
neurexophilin and PC-esterase domain family, member 3
chr13_-_62858364 0.57 ENSMUST00000021907.7
fructose bisphosphatase 2
chr9_+_51213683 0.56 ENSMUST00000034554.7
POU domain, class 2, associating factor 1
chr12_-_99883429 0.55 ENSMUST00000046485.3
EF-hand calcium binding domain 11
chr4_+_148000722 0.53 ENSMUST00000103230.4
natriuretic peptide type A
chr8_+_83955507 0.53 ENSMUST00000005607.8
ASF1 anti-silencing function 1 homolog B (S. cerevisiae)
chr18_-_47333311 0.45 ENSMUST00000126684.1
ENSMUST00000156422.1
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr5_+_123749696 0.45 ENSMUST00000031366.7
kinetochore associated 1
chr10_+_97565436 0.43 ENSMUST00000038160.4
lumican
chrX_-_48208870 0.43 ENSMUST00000088935.3
zinc finger, DHHC domain containing 9
chr9_-_106447584 0.43 ENSMUST00000171678.1
ENSMUST00000048685.6
ENSMUST00000171925.1
abhydrolase domain containing 14A
chr12_-_76795489 0.43 ENSMUST00000082431.3
glutathione peroxidase 2
chr9_-_78480736 0.43 ENSMUST00000156988.1
eukaryotic translation elongation factor 1 alpha 1
chr13_-_97747399 0.42 ENSMUST00000144993.1
RIKEN cDNA 5330416C01 gene
chr6_+_78380700 0.42 ENSMUST00000101272.1
regenerating islet-derived 3 alpha
chr3_+_145576196 0.41 ENSMUST00000098534.4
zinc finger, HIT type 6
chr19_-_11829024 0.40 ENSMUST00000061235.2
olfactory receptor 1417
chr3_+_87948666 0.36 ENSMUST00000005019.5
cellular retinoic acid binding protein II
chrX_-_102189371 0.36 ENSMUST00000033683.7
ribosomal protein S4, X-linked
chr19_+_44333092 0.35 ENSMUST00000058856.8
stearoyl-coenzyme A desaturase 4
chr1_+_164796723 0.35 ENSMUST00000027861.4
dermatopontin
chr7_+_120843551 0.35 ENSMUST00000106489.1
ENSMUST00000143279.1
eukaryotic elongation factor-2 kinase
chr11_+_3488275 0.35 ENSMUST00000064265.6
phospholipase A2, group III
chr2_+_22895482 0.34 ENSMUST00000053729.7
prenyl (solanesyl) diphosphate synthase, subunit 1
chr3_+_115888139 0.33 ENSMUST00000106505.1
ENSMUST00000043342.9
DPH5 homolog (S. cerevisiae)
chr1_+_171250416 0.32 ENSMUST00000111315.1
ENSMUST00000006570.5
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 4
chr16_+_78930940 0.32 ENSMUST00000114216.1
ENSMUST00000069148.6
ENSMUST00000023568.7
chondrolectin
chr11_+_87755567 0.32 ENSMUST00000123700.1
RIKEN cDNA A430104N18 gene
chr13_-_28953690 0.32 ENSMUST00000067230.5
SRY-box containing gene 4
chr6_+_78370877 0.31 ENSMUST00000096904.3
regenerating islet-derived 3 beta
chrX_-_48208566 0.31 ENSMUST00000037960.4
zinc finger, DHHC domain containing 9
chr13_+_16014457 0.31 ENSMUST00000164993.1
inhibin beta-A
chr18_+_4994600 0.31 ENSMUST00000140448.1
supervillin
chr5_+_65934922 0.30 ENSMUST00000153624.1
cholinergic receptor, nicotinic, alpha polypeptide 9
chr7_+_27258725 0.30 ENSMUST00000079258.6
numb-like
chr17_-_45733843 0.30 ENSMUST00000178179.1
RIKEN cDNA 1600014C23 gene
chr15_+_79229363 0.30 ENSMUST00000018295.7
ENSMUST00000053926.5
protein interacting with C kinase 1
chr10_+_86302854 0.28 ENSMUST00000132307.1
tissue inhibitor of metalloproteinase 3
chr17_-_34862122 0.28 ENSMUST00000154526.1
complement factor B
chr3_-_108415552 0.28 ENSMUST00000090558.3
cadherin, EGF LAG seven-pass G-type receptor 2 (flamingo homolog, Drosophila)
chr7_+_130577334 0.27 ENSMUST00000059145.7
ENSMUST00000084513.4
transforming, acidic coiled-coil containing protein 2
chr4_+_48045144 0.27 ENSMUST00000030025.3
nuclear receptor subfamily 4, group A, member 3
chrX_+_107088452 0.26 ENSMUST00000150494.1
purinergic receptor P2Y, G-protein coupled 10
chr9_+_89199209 0.26 ENSMUST00000068569.4
B cell leukemia/lymphoma 2 related protein A1b
chr7_+_120842824 0.26 ENSMUST00000047875.8
eukaryotic elongation factor-2 kinase
chr15_+_40655020 0.26 ENSMUST00000053467.4
zinc finger protein, multitype 2
chr7_+_131032061 0.26 ENSMUST00000084509.3
deleted in malignant brain tumors 1
chr17_-_34862473 0.26 ENSMUST00000025229.4
ENSMUST00000176203.2
ENSMUST00000128767.1
complement factor B
chr5_-_115194283 0.26 ENSMUST00000112113.1
calcium binding protein 1
chr1_-_128328311 0.25 ENSMUST00000073490.6
lactase
chr9_-_106465940 0.25 ENSMUST00000164834.1
G protein-coupled receptor 62
chr2_+_31670714 0.25 ENSMUST00000038474.7
ENSMUST00000137156.1
exosome component 2
chr12_+_84362029 0.24 ENSMUST00000110278.1
ENSMUST00000145522.1
coenzyme Q6 homolog (yeast)
chr3_+_90080442 0.24 ENSMUST00000127955.1
tropomyosin 3, gamma
chr4_-_82065889 0.23 ENSMUST00000143755.1
predicted gene 11264
chr3_+_103832562 0.23 ENSMUST00000062945.5
BCLl2-like 15
chr12_-_91746020 0.23 ENSMUST00000166967.1
stonin 2
chr7_+_24507006 0.23 ENSMUST00000176880.1
zinc finger protein 428
chr16_+_41532851 0.22 ENSMUST00000078873.4
limbic system-associated membrane protein
chr1_-_167285110 0.22 ENSMUST00000027839.8
uridine-cytidine kinase 2
chr6_-_124813065 0.22 ENSMUST00000149610.2
triosephosphate isomerase 1
chr10_-_49788743 0.22 ENSMUST00000105483.1
ENSMUST00000105487.1
glutamate receptor, ionotropic, kainate 2 (beta 2)
chr18_-_78123324 0.22 ENSMUST00000160292.1
ENSMUST00000091813.5
solute carrier family 14 (urea transporter), member 1
chr14_+_65666394 0.22 ENSMUST00000022610.8
scavenger receptor class A, member 5 (putative)
chr17_+_34238914 0.22 ENSMUST00000167280.1
histocompatibility 2, O region beta locus
chr17_-_23835743 0.22 ENSMUST00000059906.6
protease, serine, 33
chr17_+_34238896 0.21 ENSMUST00000095342.3
histocompatibility 2, O region beta locus
chr4_+_95579463 0.21 ENSMUST00000150830.1
ENSMUST00000134012.2
FGGY carbohydrate kinase domain containing
chr3_+_84952146 0.21 ENSMUST00000029727.7
F-box and WD-40 domain protein 7
chr6_+_141524379 0.20 ENSMUST00000032362.9
solute carrier organic anion transporter family, member 1c1
chr8_-_93131271 0.20 ENSMUST00000034189.8
carboxylesterase 1C
chr12_+_84361636 0.20 ENSMUST00000110276.1
coenzyme Q6 homolog (yeast)
chr14_+_70457447 0.20 ENSMUST00000003561.3
phytanoyl-CoA hydroxylase interacting protein
chr19_-_43524462 0.20 ENSMUST00000026196.7
glutamate oxaloacetate transaminase 1, soluble
chr5_+_24413406 0.20 ENSMUST00000049346.5
acid-sensing (proton-gated) ion channel 3
chr17_+_84626458 0.20 ENSMUST00000025101.8
dynein cytoplasmic 2 light intermediate chain 1
chr7_-_83735503 0.20 ENSMUST00000001792.4
interleukin 16
chr12_+_84361968 0.20 ENSMUST00000021661.6
coenzyme Q6 homolog (yeast)
chr10_+_24076500 0.19 ENSMUST00000051133.5
trace amine-associated receptor 8A
chrX_+_101429555 0.19 ENSMUST00000033673.6
non-POU-domain-containing, octamer binding protein
chr11_-_17008647 0.19 ENSMUST00000102881.3
pleckstrin
chr1_+_23761749 0.19 ENSMUST00000144602.1
beta-1,3-glucuronyltransferase 2 (glucuronosyltransferase S)
chr9_-_103222063 0.18 ENSMUST00000170904.1
transferrin
chr4_+_99272671 0.18 ENSMUST00000094956.1
predicted gene 10305
chr6_+_34746368 0.18 ENSMUST00000142716.1
caldesmon 1
chr4_-_35845204 0.18 ENSMUST00000164772.1
ENSMUST00000065173.2
leucine rich repeat and Ig domain containing 2
chr7_+_28179469 0.18 ENSMUST00000085901.6
ENSMUST00000172761.1
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b
chr8_-_84937347 0.17 ENSMUST00000109741.2
ENSMUST00000119820.1
microtubule associated serine/threonine kinase 1
chrX_+_48695004 0.17 ENSMUST00000033433.2
RNA binding motif protein, X-linked 2
chr2_-_32387760 0.17 ENSMUST00000050785.8
lipocalin 2
chr2_+_3114220 0.17 ENSMUST00000072955.5
family with sequence similarity 171, member A1
chr9_-_123978297 0.17 ENSMUST00000071404.3
chemokine (C-C motif) receptor 1-like 1
chr17_-_73950172 0.17 ENSMUST00000024866.4
xanthine dehydrogenase
chr7_+_27653906 0.17 ENSMUST00000008088.7
tetratricopeptide repeat domain 9B
chr2_+_33216051 0.17 ENSMUST00000004208.5
angiopoietin-like 2
chrX_+_56894372 0.17 ENSMUST00000136396.1
G protein-coupled receptor 112
chr10_-_58675631 0.16 ENSMUST00000003312.4
ectodysplasin-A receptor
chr16_+_65815508 0.16 ENSMUST00000168064.1
vestigial like 3 (Drosophila)
chr13_+_23695791 0.16 ENSMUST00000041052.2
histone cluster 1, H1t
chr2_-_25224653 0.16 ENSMUST00000043584.4
tubulin, beta 4B class IVB
chr3_+_103832741 0.16 ENSMUST00000106822.1
BCLl2-like 15
chr7_-_25788635 0.16 ENSMUST00000002677.4
ENSMUST00000085948.4
AXL receptor tyrosine kinase
chr2_+_59484645 0.15 ENSMUST00000028369.5
death associated protein-like 1
chr1_-_45503282 0.15 ENSMUST00000086430.4
collagen, type V, alpha 2
chr17_+_5799491 0.15 ENSMUST00000181484.1
RIKEN cDNA 3300005D01 gene
chr19_-_34255325 0.15 ENSMUST00000039631.8
actin, alpha 2, smooth muscle, aorta
chr8_+_31091593 0.15 ENSMUST00000161713.1
dual specificity phosphatase 26 (putative)
chr19_-_11856001 0.15 ENSMUST00000079875.3
olfactory receptor 1418
chr6_-_78378851 0.15 ENSMUST00000089667.1
ENSMUST00000167492.1
regenerating islet-derived 3 delta
chrX_+_104482774 0.14 ENSMUST00000087867.5
uracil phosphoribosyltransferase (FUR1) homolog (S. cerevisiae)
chrX_+_134601179 0.14 ENSMUST00000074950.4
ENSMUST00000113203.1
ENSMUST00000113202.1
heterogeneous nuclear ribonucleoprotein H2
chr19_+_24673998 0.14 ENSMUST00000057243.4
transmembrane protein 252
chr16_+_27389911 0.14 ENSMUST00000143823.1
coiled-coil domain containing 50
chr11_+_4895316 0.14 ENSMUST00000101615.2
THO complex 5
chr17_+_45506825 0.14 ENSMUST00000024733.7
alanyl-tRNA synthetase 2, mitochondrial (putative)
chr19_+_56287943 0.13 ENSMUST00000166049.1
hyaluronic acid binding protein 2
chr11_+_4895328 0.13 ENSMUST00000038237.1
THO complex 5
chr17_-_63863791 0.13 ENSMUST00000050753.3
RIKEN cDNA A930002H24 gene
chrX_-_100412587 0.13 ENSMUST00000033567.8
acyl-CoA wax alcohol acyltransferase 2
chr6_-_99044414 0.13 ENSMUST00000177507.1
ENSMUST00000123992.1
forkhead box P1
chr13_+_83504032 0.13 ENSMUST00000163888.1
ENSMUST00000005722.7
myocyte enhancer factor 2C
chr4_+_130055010 0.12 ENSMUST00000123617.1
collagen, type XVI, alpha 1
chr3_-_127409014 0.12 ENSMUST00000182008.1
ENSMUST00000182711.1
ENSMUST00000182547.1
ankyrin 2, brain
chr16_-_26989974 0.12 ENSMUST00000089832.4
geminin coiled-coil domain containing
chr19_+_11895999 0.12 ENSMUST00000072784.2
olfactory receptor 1420
chr6_-_128355826 0.12 ENSMUST00000001562.6
tubby-like protein 3
chr7_-_27195727 0.12 ENSMUST00000163311.2
ENSMUST00000126211.1
small nuclear ribonucleoprotein polypeptide A
chr7_+_130936172 0.12 ENSMUST00000006367.7
HtrA serine peptidase 1
chr8_+_110618577 0.12 ENSMUST00000034190.9
Vac14 homolog (S. cerevisiae)
chr3_+_92288566 0.12 ENSMUST00000090872.4
small proline-rich protein 2A3
chr14_+_27000362 0.12 ENSMUST00000035433.8
homeobox gene expressed in ES cells
chr11_-_75348261 0.12 ENSMUST00000000767.5
ENSMUST00000092907.5
replication protein A1
chr19_+_4962306 0.12 ENSMUST00000025836.4
mitochondrial ribosomal protein L11
chr17_+_84511832 0.12 ENSMUST00000047206.5
pleckstrin homology domain containing, family H (with MyTH4 domain) member 2
chr5_-_103977326 0.11 ENSMUST00000120320.1
hydroxysteroid (17-beta) dehydrogenase 13
chr11_+_77216180 0.11 ENSMUST00000037912.5
ENSMUST00000156488.1
slingshot homolog 2 (Drosophila)
chr19_-_40588338 0.11 ENSMUST00000176939.1
aldehyde dehydrogenase 18 family, member A1
chr19_-_40588453 0.11 ENSMUST00000025979.6
aldehyde dehydrogenase 18 family, member A1
chr2_+_163995503 0.11 ENSMUST00000131288.1
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide
chr16_+_20673517 0.11 ENSMUST00000115460.1
eukaryotic translation initiation factor 4, gamma 1
chr17_+_75465538 0.11 ENSMUST00000095204.4
RAS, guanyl releasing protein 3
chr5_-_87092546 0.11 ENSMUST00000132667.1
ENSMUST00000145617.1
ENSMUST00000094649.4
UDP glucuronosyltransferase 2 family, polypeptide B36
chr8_-_115706994 0.11 ENSMUST00000069009.6
avian musculoaponeurotic fibrosarcoma (v-maf) AS42 oncogene homolog
chr2_+_29346803 0.11 ENSMUST00000028139.4
ENSMUST00000113830.4
mediator complex subunit 27
chr11_-_116654245 0.11 ENSMUST00000021166.5
cytoglobin
chr4_-_133967953 0.11 ENSMUST00000102553.4
high mobility group nucleosomal binding domain 2
chr1_-_138175126 0.11 ENSMUST00000183301.1
protein tyrosine phosphatase, receptor type, C
chr8_+_94472763 0.10 ENSMUST00000053085.5
NLR family, CARD domain containing 5
chr1_-_64121389 0.10 ENSMUST00000055001.3
Kruppel-like factor 7 (ubiquitous)
chr1_-_52500679 0.10 ENSMUST00000069792.7
Ngfi-A binding protein 1
chr16_+_20673264 0.10 ENSMUST00000154950.1
ENSMUST00000115461.1
eukaryotic translation initiation factor 4, gamma 1
chr7_+_25659153 0.10 ENSMUST00000079634.6
exosome component 5
chr13_+_41655697 0.10 ENSMUST00000067176.8
predicted gene 5082
chr7_-_19715395 0.10 ENSMUST00000032555.9
ENSMUST00000093552.5
translocase of outer mitochondrial membrane 40 homolog (yeast)
chr4_-_11981265 0.10 ENSMUST00000098260.2
predicted gene 10604
chr9_-_71592265 0.10 ENSMUST00000166843.1
ENSMUST00000163998.1
ENSMUST00000169573.1
GRINL1A complex locus
myocardial zonula adherens protein
chr18_-_67724560 0.10 ENSMUST00000120934.1
ENSMUST00000025420.7
ENSMUST00000122412.1
protein tyrosine phosphatase, non-receptor type 2
chr1_-_162859919 0.10 ENSMUST00000134098.1
ENSMUST00000111518.1
flavin containing monooxygenase 1
chr5_-_103977360 0.10 ENSMUST00000048118.8
hydroxysteroid (17-beta) dehydrogenase 13
chr18_-_37954958 0.10 ENSMUST00000043498.7
histone deacetylase 3
chrX_+_56963325 0.10 ENSMUST00000096431.3
G protein-coupled receptor 112
chr19_-_40588374 0.10 ENSMUST00000175932.1
ENSMUST00000176955.1
ENSMUST00000149476.2
aldehyde dehydrogenase 18 family, member A1
chr11_-_94549165 0.09 ENSMUST00000040487.3
radical S-adenosyl methionine domain containing 1
chr6_+_135362931 0.09 ENSMUST00000032330.9
epithelial membrane protein 1
chr1_-_180330550 0.09 ENSMUST00000050581.3
predicted pseudogene 5069
chr8_+_95534078 0.09 ENSMUST00000041569.3
coiled-coil domain containing 113
chr5_-_103977404 0.09 ENSMUST00000112803.2
hydroxysteroid (17-beta) dehydrogenase 13
chr10_-_127370535 0.09 ENSMUST00000026472.8
inhibin beta-C
chr7_+_28180226 0.09 ENSMUST00000172467.1
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b
chr7_-_105399991 0.09 ENSMUST00000118726.1
ENSMUST00000074686.7
ENSMUST00000122327.1
ENSMUST00000179474.1
ENSMUST00000048079.6
family with sequence similarity 160, member A2
chr3_-_127408937 0.09 ENSMUST00000183095.1
ENSMUST00000182610.1
ankyrin 2, brain
chr2_+_167777467 0.09 ENSMUST00000139927.1
ENSMUST00000127441.1
predicted gene 14321
chrX_-_167855061 0.09 ENSMUST00000112146.1
FERM and PDZ domain containing 4
chr1_-_138175283 0.09 ENSMUST00000182755.1
ENSMUST00000183262.1
ENSMUST00000027645.7
ENSMUST00000112036.2
ENSMUST00000182283.1
protein tyrosine phosphatase, receptor type, C
chr6_-_115251839 0.09 ENSMUST00000032462.6
tissue inhibitor of metalloproteinase 4
chrX_+_101377267 0.09 ENSMUST00000052130.7
gap junction protein, beta 1
chr18_-_39490649 0.09 ENSMUST00000115567.1
nuclear receptor subfamily 3, group C, member 1
chr18_+_37955126 0.08 ENSMUST00000176902.1
ENSMUST00000176104.1
RELT-like 2
chrX_-_79434418 0.08 ENSMUST00000179788.1
calponin homology domain containing 2
chr1_-_155417394 0.08 ENSMUST00000111775.1
ENSMUST00000111774.1
xenotropic and polytropic retrovirus receptor 1
chr8_+_58911755 0.08 ENSMUST00000062978.6
cDNA sequence BC030500
chr16_-_59555752 0.08 ENSMUST00000179383.1
ENSMUST00000044604.8
beta-gamma crystallin domain containing 3
chr2_+_52038005 0.08 ENSMUST00000065927.5
tumor necrosis factor alpha induced protein 6
chr11_+_54314896 0.08 ENSMUST00000072178.4
ENSMUST00000101211.2
ENSMUST00000101213.2
acyl-CoA synthetase long-chain family member 6
chr9_+_32372409 0.08 ENSMUST00000047334.8
potassium inwardly-rectifying channel, subfamily J, member 1
chr12_-_83487708 0.08 ENSMUST00000177959.1
ENSMUST00000178756.1
D4, zinc and double PHD fingers, family 3
chr7_+_30776394 0.07 ENSMUST00000041703.7
dermokine
chr4_+_56743406 0.07 ENSMUST00000095079.4
actin-like 7a
chr10_-_95415283 0.07 ENSMUST00000119917.1
suppressor of cytokine signaling 2
chr16_+_43235856 0.07 ENSMUST00000146708.1
zinc finger and BTB domain containing 20
chr11_+_115974930 0.07 ENSMUST00000106460.2
integrin beta 4
chr7_+_28180272 0.07 ENSMUST00000173223.1
dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1b

Network of associatons between targets according to the STRING database.

First level regulatory network of Nfix

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.9 GO:0060011 Sertoli cell proliferation(GO:0060011) prostate epithelial cord elongation(GO:0060523)
0.2 0.6 GO:0046351 disaccharide biosynthetic process(GO:0046351)
0.1 0.4 GO:0009174 UMP biosynthetic process(GO:0006222) pyrimidine ribonucleoside monophosphate metabolic process(GO:0009173) pyrimidine ribonucleoside monophosphate biosynthetic process(GO:0009174) UMP metabolic process(GO:0046049)
0.1 0.4 GO:0002587 negative regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002587)
0.1 0.5 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.1 0.3 GO:0006592 ornithine biosynthetic process(GO:0006592)
0.1 0.3 GO:0021849 neuroblast division in subventricular zone(GO:0021849)
0.1 0.5 GO:0032914 positive regulation of transforming growth factor beta1 production(GO:0032914)
0.1 1.1 GO:0019373 epoxygenase P450 pathway(GO:0019373)
0.1 0.6 GO:0009313 oligosaccharide catabolic process(GO:0009313)
0.1 0.3 GO:0032765 positive regulation of mast cell cytokine production(GO:0032765) Fc-epsilon receptor signaling pathway(GO:0038095) vestibular reflex(GO:0060005)
0.1 0.4 GO:1903964 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.1 0.3 GO:0071051 polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.1 0.3 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.1 0.3 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.1 0.3 GO:0035905 ascending aorta development(GO:0035905) ascending aorta morphogenesis(GO:0035910)
0.1 0.2 GO:0019405 alditol catabolic process(GO:0019405) glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
0.1 0.2 GO:0071918 urea transmembrane transport(GO:0071918)
0.1 0.3 GO:1903984 positive regulation of TRAIL-activated apoptotic signaling pathway(GO:1903984)
0.1 0.4 GO:0048254 snoRNA localization(GO:0048254)
0.1 0.7 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.1 0.2 GO:0006533 fumarate metabolic process(GO:0006106) glycerol biosynthetic process(GO:0006114) aspartate biosynthetic process(GO:0006532) aspartate catabolic process(GO:0006533)
0.1 0.2 GO:1903377 negative regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903377)
0.1 0.4 GO:2000002 negative regulation of DNA damage checkpoint(GO:2000002)
0.1 0.3 GO:0060279 regulation of ovulation(GO:0060278) positive regulation of ovulation(GO:0060279)
0.1 0.3 GO:0033326 cerebrospinal fluid secretion(GO:0033326)
0.1 1.0 GO:0006744 ubiquinone biosynthetic process(GO:0006744)
0.1 0.2 GO:0097350 neutrophil clearance(GO:0097350)
0.1 0.3 GO:0010040 response to iron(II) ion(GO:0010040)
0.1 0.2 GO:1902310 positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
0.1 0.2 GO:0050915 sensory perception of sour taste(GO:0050915)
0.0 0.4 GO:0045617 negative regulation of keratinocyte differentiation(GO:0045617)
0.0 0.1 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.0 0.3 GO:1903207 neuron death in response to hydrogen peroxide(GO:0036476) regulation of hydrogen peroxide-induced neuron death(GO:1903207) negative regulation of hydrogen peroxide-induced neuron death(GO:1903208)
0.0 0.2 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.0 0.1 GO:0007521 muscle cell fate determination(GO:0007521)
0.0 0.2 GO:0009115 xanthine catabolic process(GO:0009115)
0.0 0.5 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.2 GO:0002378 immunoglobulin biosynthetic process(GO:0002378) regulation of hematopoietic stem cell migration(GO:2000471) positive regulation of hematopoietic stem cell migration(GO:2000473)
0.0 0.3 GO:0019372 lipoxygenase pathway(GO:0019372)
0.0 0.2 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.0 0.2 GO:0010920 negative regulation of inositol phosphate biosynthetic process(GO:0010920) protein secretion by platelet(GO:0070560)
0.0 0.3 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.0 0.1 GO:0070104 negative regulation of interleukin-6-mediated signaling pathway(GO:0070104) regulation of macrophage colony-stimulating factor signaling pathway(GO:1902226) regulation of response to macrophage colony-stimulating factor(GO:1903969) regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903972)
0.0 0.4 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.0 0.2 GO:1901678 iron coordination entity transport(GO:1901678)
0.0 0.2 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.0 0.9 GO:0000154 rRNA modification(GO:0000154)
0.0 0.1 GO:0015671 oxygen transport(GO:0015671)
0.0 0.1 GO:0021914 negative regulation of smoothened signaling pathway involved in ventral spinal cord patterning(GO:0021914)
0.0 0.1 GO:0010166 wax biosynthetic process(GO:0010025) wax metabolic process(GO:0010166)
0.0 0.2 GO:2000491 positive regulation of hepatic stellate cell activation(GO:2000491)
0.0 0.2 GO:0098707 ferrous iron import into cell(GO:0097460) ferrous iron import across plasma membrane(GO:0098707)
0.0 0.2 GO:0060605 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.0 0.2 GO:0036309 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.0 0.1 GO:1903334 protein targeting to vacuole involved in autophagy(GO:0071211) lysosomal membrane organization(GO:0097212) positive regulation of protein folding(GO:1903334)
0.0 0.7 GO:0010866 regulation of triglyceride biosynthetic process(GO:0010866)
0.0 0.4 GO:0042573 retinoic acid metabolic process(GO:0042573)
0.0 0.1 GO:0060578 subthalamic nucleus development(GO:0021763) superior vena cava morphogenesis(GO:0060578)
0.0 0.1 GO:0060718 chorionic trophoblast cell differentiation(GO:0060718)
0.0 0.1 GO:0046826 negative regulation of protein export from nucleus(GO:0046826)
0.0 0.1 GO:0061373 mammillary body development(GO:0021767) mammillary axonal complex development(GO:0061373) positive regulation of lens fiber cell differentiation(GO:1902748)
0.0 0.1 GO:1903575 cornified envelope assembly(GO:1903575)
0.0 0.2 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 0.2 GO:2000507 positive regulation of energy homeostasis(GO:2000507)
0.0 0.1 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.0 1.0 GO:0006414 translational elongation(GO:0006414)
0.0 0.5 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.3 GO:0030953 astral microtubule organization(GO:0030953)
0.0 0.2 GO:0019321 pentose metabolic process(GO:0019321)
0.0 0.4 GO:2001224 positive regulation of neuron migration(GO:2001224)
0.0 0.1 GO:1900170 negative regulation of glucocorticoid mediated signaling pathway(GO:1900170)
0.0 0.0 GO:0033563 dorsal/ventral axon guidance(GO:0033563)
0.0 0.3 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.1 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.0 0.0 GO:0006295 pyrimidine dimer repair by nucleotide-excision repair(GO:0000720) nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295) nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296) positive regulation of t-circle formation(GO:1904431)
0.0 0.1 GO:0045345 MHC class I biosynthetic process(GO:0045341) regulation of MHC class I biosynthetic process(GO:0045343) positive regulation of MHC class I biosynthetic process(GO:0045345) positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.0 0.1 GO:0051835 positive regulation of synapse structural plasticity(GO:0051835)
0.0 0.0 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528)
0.0 0.1 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0 0.2 GO:0034755 iron ion transmembrane transport(GO:0034755)
0.0 0.0 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.0 0.1 GO:0051581 negative regulation of neurotransmitter uptake(GO:0051581) negative regulation of serotonin uptake(GO:0051612)
0.0 0.1 GO:0043654 recognition of apoptotic cell(GO:0043654)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.9 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.2 0.5 GO:1990423 RZZ complex(GO:1990423)
0.1 0.9 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.1 0.3 GO:0043512 inhibin A complex(GO:0043512)
0.1 0.3 GO:0098842 postsynaptic early endosome(GO:0098842)
0.1 0.8 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.1 0.4 GO:0070761 pre-snoRNP complex(GO:0070761)
0.1 0.5 GO:0042629 mast cell granule(GO:0042629)
0.1 0.2 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.1 0.2 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.2 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.0 0.4 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.3 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.0 0.4 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.3 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.3 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.2 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.0 0.2 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.2 GO:0042382 paraspeckles(GO:0042382)
0.0 0.1 GO:0044530 supraspliceosomal complex(GO:0044530)
0.0 0.3 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.2 GO:0030478 actin cap(GO:0030478)
0.0 0.1 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0 0.2 GO:0005862 muscle thin filament tropomyosin(GO:0005862)
0.0 0.2 GO:0097433 dense body(GO:0097433)
0.0 0.2 GO:0045298 tubulin complex(GO:0045298)
0.0 0.1 GO:0099522 lysosomal lumen(GO:0043202) region of cytosol(GO:0099522) postsynaptic cytosol(GO:0099524)
0.0 0.1 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 0.0 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.0 0.3 GO:0042588 zymogen granule(GO:0042588)
0.0 0.1 GO:0070695 FHF complex(GO:0070695)
0.0 0.1 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.1 GO:0001533 cornified envelope(GO:0001533)
0.0 0.1 GO:0005688 U6 snRNP(GO:0005688)
0.0 0.2 GO:0001673 male germ cell nucleus(GO:0001673)
0.0 0.5 GO:0043034 costamere(GO:0043034)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.9 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798)
0.2 0.6 GO:0004686 elongation factor-2 kinase activity(GO:0004686)
0.2 0.6 GO:0052795 exo-alpha-sialidase activity(GO:0004308) alpha-sialidase activity(GO:0016997) exo-alpha-(2->3)-sialidase activity(GO:0052794) exo-alpha-(2->6)-sialidase activity(GO:0052795) exo-alpha-(2->8)-sialidase activity(GO:0052796)
0.1 0.3 GO:0004349 glutamate 5-kinase activity(GO:0004349) glutamate-5-semialdehyde dehydrogenase activity(GO:0004350) delta1-pyrroline-5-carboxylate synthetase activity(GO:0017084) amino acid kinase activity(GO:0019202)
0.1 0.4 GO:0032896 palmitoyl-CoA 9-desaturase activity(GO:0032896)
0.1 0.3 GO:0050347 trans-hexaprenyltranstransferase activity(GO:0000010) trans-octaprenyltranstransferase activity(GO:0050347)
0.1 1.1 GO:0008392 arachidonic acid epoxygenase activity(GO:0008392)
0.1 0.4 GO:0004849 uridine kinase activity(GO:0004849)
0.1 0.2 GO:0019150 D-ribulokinase activity(GO:0019150)
0.1 0.2 GO:0080130 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069) L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.1 0.9 GO:1990226 histone methyltransferase binding(GO:1990226)
0.1 0.5 GO:0001094 TFIID-class transcription factor binding(GO:0001094)
0.1 0.7 GO:0005549 odorant binding(GO:0005549)
0.1 0.2 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.0 0.1 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.0 0.1 GO:0050252 retinol O-fatty-acyltransferase activity(GO:0050252)
0.0 0.2 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.0 0.2 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 0.3 GO:0008422 beta-glucosidase activity(GO:0008422)
0.0 0.2 GO:0004854 xanthine dehydrogenase activity(GO:0004854) oxidoreductase activity, acting on CH or CH2 groups, NAD or NADP as acceptor(GO:0016726)
0.0 0.3 GO:0070699 type II activin receptor binding(GO:0070699)
0.0 0.2 GO:0070287 ferritin receptor activity(GO:0070287)
0.0 0.6 GO:0050308 sugar-phosphatase activity(GO:0050308)
0.0 0.2 GO:0015265 urea channel activity(GO:0015265)
0.0 0.1 GO:0097677 STAT family protein binding(GO:0097677)
0.0 0.2 GO:0070513 death domain binding(GO:0070513)
0.0 0.5 GO:0051428 peptide hormone receptor binding(GO:0051428)
0.0 0.2 GO:0015349 thyroid hormone transmembrane transporter activity(GO:0015349)
0.0 0.1 GO:0005344 catalase activity(GO:0004096) oxygen transporter activity(GO:0005344)
0.0 0.2 GO:0015091 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.0 0.4 GO:0019841 retinal binding(GO:0016918) retinol binding(GO:0019841)
0.0 0.7 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.4 GO:0008191 metalloendopeptidase inhibitor activity(GO:0008191)
0.0 0.2 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 0.5 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.5 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.0 0.3 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.6 GO:0071949 FAD binding(GO:0071949)
0.0 0.3 GO:0022848 acetylcholine-gated cation channel activity(GO:0022848)
0.0 0.1 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.0 0.1 GO:0030621 U4 snRNA binding(GO:0030621)
0.0 0.3 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.1 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.0 0.2 GO:0016861 intramolecular oxidoreductase activity, interconverting aldoses and ketoses(GO:0016861)
0.0 0.1 GO:0050815 phosphoserine binding(GO:0050815)
0.0 0.2 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.0 0.4 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.2 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.4 GO:0005540 hyaluronic acid binding(GO:0005540)
0.0 0.1 GO:0035614 snRNA stem-loop binding(GO:0035614)
0.0 0.1 GO:0038049 glucocorticoid receptor activity(GO:0004883) transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.0 0.4 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.1 GO:0016634 oxidoreductase activity, acting on the CH-CH group of donors, oxygen as acceptor(GO:0016634)
0.0 0.1 GO:0015272 ATP-activated inward rectifier potassium channel activity(GO:0015272)
0.0 0.1 GO:0015288 porin activity(GO:0015288)
0.0 0.8 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.3 GO:0051400 BH domain binding(GO:0051400)
0.0 0.0 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.2 GO:0045504 dynein heavy chain binding(GO:0045504)
0.0 0.2 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 0.0 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.1 GO:0038132 neuregulin binding(GO:0038132)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.9 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 0.6 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 0.8 ST GA12 PATHWAY G alpha 12 Pathway
0.0 0.8 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 REACTOME XENOBIOTICS Genes involved in Xenobiotics
0.1 0.3 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.1 0.8 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling
0.1 0.4 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.0 0.5 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.3 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 1.7 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.0 0.3 REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.0 0.3 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 1.1 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 0.3 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 1.0 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.7 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.3 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.0 0.5 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.2 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.0 0.6 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.2 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.5 REACTOME YAP1 AND WWTR1 TAZ STIMULATED GENE EXPRESSION Genes involved in YAP1- and WWTR1 (TAZ)-stimulated gene expression
0.0 0.2 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.3 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.3 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 0.1 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.1 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0 0.1 REACTOME CIRCADIAN REPRESSION OF EXPRESSION BY REV ERBA Genes involved in Circadian Repression of Expression by REV-ERBA