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2D miR_HR1_12

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Results for Foxa2_Foxa1

Z-value: 1.84

Motif logo

Transcription factors associated with Foxa2_Foxa1

Gene Symbol Gene ID Gene Info
ENSMUSG00000037025.5 forkhead box A2
ENSMUSG00000035451.6 forkhead box A1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Foxa2mm10_v2_chr2_-_148046896_148046991-0.863.1e-04Click!
Foxa1mm10_v2_chr12_-_57546121_57546141-0.701.1e-02Click!

Activity profile of Foxa2_Foxa1 motif

Sorted Z-values of Foxa2_Foxa1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr4_+_104766334 9.12 ENSMUST00000065072.6
complement component 8, beta polypeptide
chr4_+_104766308 7.73 ENSMUST00000031663.3
complement component 8, beta polypeptide
chr3_-_113258837 6.44 ENSMUST00000098673.3
amylase 2a5
chr3_-_113532288 5.54 ENSMUST00000132353.1
amylase 2a1
chr2_-_62483637 4.70 ENSMUST00000136686.1
ENSMUST00000102733.3
glucagon
chrX_-_108664891 4.36 ENSMUST00000178160.1
predicted gene 379
chr6_+_90619241 4.27 ENSMUST00000032177.8
solute carrier family 41, member 3
chr5_-_108795352 4.08 ENSMUST00000004943.1
transmembrane emp24 protein transport domain containing
chr6_+_30541582 3.73 ENSMUST00000096066.4
carboxypeptidase A2, pancreatic
chrX_+_101376359 3.54 ENSMUST00000119080.1
gap junction protein, beta 1
chr2_+_164403194 3.53 ENSMUST00000017151.1
recombination signal binding protein for immunoglobulin kappa J region-like
chr14_+_103513328 3.42 ENSMUST00000095576.3
sciellin
chr17_-_31144271 3.36 ENSMUST00000024826.7
trefoil factor 2 (spasmolytic protein 1)
chr10_+_115817247 3.34 ENSMUST00000035563.7
ENSMUST00000080630.3
ENSMUST00000179196.1
tetraspanin 8
chr16_-_22439719 3.30 ENSMUST00000079601.6
ets variant gene 5
chr6_-_136922169 2.97 ENSMUST00000032343.6
endoplasmic reticulum protein 27
chr7_+_131032061 2.96 ENSMUST00000084509.3
deleted in malignant brain tumors 1
chr17_+_70522083 2.89 ENSMUST00000148486.1
ENSMUST00000133717.1
discs, large (Drosophila) homolog-associated protein 1
chr3_-_20275659 2.88 ENSMUST00000011607.5
carboxypeptidase B1 (tissue)
chrX_+_164140447 2.86 ENSMUST00000073973.4
angiotensin I converting enzyme (peptidyl-dipeptidase A) 2
chr11_+_96929260 2.82 ENSMUST00000054311.5
ENSMUST00000107636.3
proline rich 15-like
chr5_-_86906937 2.72 ENSMUST00000031181.9
ENSMUST00000113333.1
UDP glucuronosyltransferase 2 family, polypeptide B34
chr11_+_96929367 2.65 ENSMUST00000062172.5
proline rich 15-like
chr12_-_103657159 2.61 ENSMUST00000044159.6
serine (or cysteine) peptidase inhibitor, clade A, member 6
chr9_+_74848437 2.61 ENSMUST00000161862.1
ENSMUST00000162089.1
ENSMUST00000160017.1
ENSMUST00000160950.1
predicted gene 16551
predicted gene 20649
chr11_-_99986593 2.38 ENSMUST00000105050.2
keratin associated protein 16-1
chr11_-_100146120 2.35 ENSMUST00000007317.7
keratin 19
chr11_+_32000452 2.17 ENSMUST00000020537.2
ENSMUST00000109409.1
neuron specific gene family member 2
chr13_-_95478655 2.11 ENSMUST00000022186.3
S100 calcium binding protein, zeta
chr4_-_57916283 2.08 ENSMUST00000063816.5
RIKEN cDNA D630039A03 gene
chr18_-_60648290 2.04 ENSMUST00000143275.2
synaptopodin
chr10_-_93311073 2.02 ENSMUST00000008542.5
ELK3, member of ETS oncogene family
chr10_-_93310963 2.02 ENSMUST00000151153.1
ELK3, member of ETS oncogene family
chr6_-_87388878 2.01 ENSMUST00000032127.4
gastrokine 3
chr1_-_74885322 1.91 ENSMUST00000159232.1
ENSMUST00000068631.3
FEV (ETS oncogene family)
chr5_+_102481374 1.85 ENSMUST00000094559.2
ENSMUST00000073302.5
Rho GTPase activating protein 24
chr9_+_37539255 1.82 ENSMUST00000002008.5
V-set and immunoglobulin domain containing 2
chr9_-_107668967 1.78 ENSMUST00000177567.1
solute carrier family 38, member 3
chr14_+_41131777 1.73 ENSMUST00000022314.3
ENSMUST00000170719.1
surfactant associated protein A1
chr11_+_94565039 1.72 ENSMUST00000040418.8
chondroadherin
chr16_+_17331371 1.70 ENSMUST00000023450.6
ENSMUST00000161034.1
serine (or cysteine) peptidase inhibitor, clade D, member 1
chr3_-_106167564 1.65 ENSMUST00000063062.8
chitinase 3-like 3
chr17_+_70522149 1.63 ENSMUST00000140728.1
discs, large (Drosophila) homolog-associated protein 1
chr5_+_102481546 1.60 ENSMUST00000112854.1
Rho GTPase activating protein 24
chr1_+_156838915 1.53 ENSMUST00000111720.1
angiopoietin-like 1
chr11_+_87699897 1.53 ENSMUST00000040089.4
ring finger protein 43
chr5_-_123865491 1.52 ENSMUST00000057145.5
niacin receptor 1
chr14_-_110755100 1.50 ENSMUST00000078386.2
SLIT and NTRK-like family, member 6
chr11_-_68386821 1.47 ENSMUST00000021284.3
netrin 1
chr14_+_73237891 1.44 ENSMUST00000044405.6
lysophosphatidic acid receptor 6
chr6_-_41446062 1.42 ENSMUST00000095999.5
predicted gene 10334
chr8_-_45294854 1.40 ENSMUST00000116473.2
kallikrein B, plasma 1
chr10_-_41611319 1.35 ENSMUST00000179614.1
coiled-coil domain containing 162
chr17_+_68837062 1.34 ENSMUST00000178545.1
transmembrane protein 200C
chr16_+_33518278 1.33 ENSMUST00000122427.1
ENSMUST00000059056.8
solute carrier family 12 (potassium/chloride transporters), member 8
chr2_-_172940299 1.33 ENSMUST00000009143.7
bone morphogenetic protein 7
chr4_+_102570065 1.32 ENSMUST00000097950.2
phosphodiesterase 4B, cAMP specific
chr11_+_110399115 1.30 ENSMUST00000020949.5
ENSMUST00000100260.1
mitogen-activated protein kinase kinase 6
chr4_-_103026709 1.26 ENSMUST00000084382.5
ENSMUST00000106869.2
insulin-like 5
chr16_+_33518528 1.22 ENSMUST00000119173.1
solute carrier family 12 (potassium/chloride transporters), member 8
chr2_-_163645125 1.20 ENSMUST00000017851.3
serine incorporator 3
chr2_-_72813665 1.19 ENSMUST00000136807.1
ENSMUST00000148327.1
RIKEN cDNA 6430710C18 gene
chr6_+_5390387 1.18 ENSMUST00000183358.1
ankyrin repeat and SOCS box-containing 4
chr19_-_58455398 1.16 ENSMUST00000026076.7
glial cell line derived neurotrophic factor family receptor alpha 1
chr3_+_69222412 1.15 ENSMUST00000183126.1
ADP-ribosylation factor-like 14
chr16_+_22892035 1.14 ENSMUST00000023583.5
alpha-2-HS-glycoprotein
chr3_-_113291449 1.10 ENSMUST00000179568.1
amylase 2a4
chr3_-_113324052 1.10 ENSMUST00000179314.1
amylase 2a3
chr3_-_101836223 1.07 ENSMUST00000061831.4
mab-21-like 3 (C. elegans)
chr3_-_145032765 1.06 ENSMUST00000029919.5
chloride channel calcium activated 3
chr14_-_93888732 1.06 ENSMUST00000068992.2
protocadherin 9
chr15_-_66560997 1.05 ENSMUST00000048372.5
transmembrane protein 71
chr6_+_97991776 1.04 ENSMUST00000043628.6
microphthalmia-associated transcription factor
chr14_-_41185188 1.04 ENSMUST00000077136.3
surfactant associated protein D
chr2_+_26973416 1.03 ENSMUST00000014996.7
ENSMUST00000102891.3
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 13
chr1_-_39720989 1.03 ENSMUST00000151913.1
regulatory factor X 8
chr1_+_179546303 1.03 ENSMUST00000040706.8
consortin, connexin sorting protein
chr12_+_119443410 1.01 ENSMUST00000048880.6
metastasis associated in colon cancer 1
chr5_+_75152274 0.99 ENSMUST00000000476.8
platelet derived growth factor receptor, alpha polypeptide
chr16_-_22657182 0.99 ENSMUST00000023578.7
diacylglycerol kinase, gamma
chr17_-_56121946 0.98 ENSMUST00000041357.7
leucine-rich alpha-2-glycoprotein 1
chr10_-_128180265 0.97 ENSMUST00000099139.1
RNA binding motif, single stranded interacting protein 2
chr15_+_10223974 0.95 ENSMUST00000128450.1
ENSMUST00000148257.1
ENSMUST00000128921.1
prolactin receptor
chr3_+_19957240 0.95 ENSMUST00000108325.2
ceruloplasmin
chr8_+_127064022 0.94 ENSMUST00000160272.1
ENSMUST00000079777.5
ENSMUST00000162907.1
par-3 (partitioning defective 3) homolog (C. elegans)
chr10_+_87861309 0.94 ENSMUST00000122100.1
insulin-like growth factor 1
chr6_+_34863130 0.94 ENSMUST00000074949.3
transmembrane protein 140
chr1_-_87573825 0.93 ENSMUST00000068681.5
neuronal guanine nucleotide exchange factor
chr14_+_55853997 0.90 ENSMUST00000100529.3
NYN domain and retroviral integrase containing
chr3_+_135825648 0.89 ENSMUST00000180196.1
solute carrier family 39 (metal ion transporter), member 8
chr7_-_29168647 0.88 ENSMUST00000048923.6
sprouty-related, EVH1 domain containing 3
chr4_-_63154130 0.88 ENSMUST00000030041.4
alpha 1 microglobulin/bikunin
chr4_+_150853919 0.88 ENSMUST00000073600.2
ERBB receptor feedback inhibitor 1
chr7_-_100656953 0.87 ENSMUST00000107046.1
ENSMUST00000107045.1
ENSMUST00000139708.1
pleckstrin homology domain containing, family B (evectins) member 1
chr8_+_107119110 0.85 ENSMUST00000046116.1
RIKEN cDNA C630050I24 gene
chr9_+_46228580 0.84 ENSMUST00000034588.8
apolipoprotein A-I
chr6_+_139843648 0.83 ENSMUST00000087657.6
phosphatidylinositol 3-kinase, C2 domain containing, gamma polypeptide
chr8_-_65129317 0.81 ENSMUST00000098713.3
cDNA sequence BC030870
chr14_-_30943275 0.81 ENSMUST00000006704.8
ENSMUST00000163118.1
inter-alpha trypsin inhibitor, heavy chain 1
chr2_-_70825726 0.81 ENSMUST00000038584.8
tousled-like kinase 1
chr13_+_111867931 0.81 ENSMUST00000128198.1
predicted gene 15326
chr16_-_22161450 0.80 ENSMUST00000115379.1
insulin-like growth factor 2 mRNA binding protein 2
chr2_+_125136692 0.78 ENSMUST00000099452.2
cortexin 2
chr14_+_55854115 0.77 ENSMUST00000168479.1
NYN domain and retroviral integrase containing
chr2_+_137663424 0.75 ENSMUST00000134833.1
predicted gene 14064
chr18_+_69925542 0.75 ENSMUST00000080050.5
coiled-coil domain containing 68
chr4_-_55532453 0.75 ENSMUST00000132746.1
ENSMUST00000107619.2
Kruppel-like factor 4 (gut)
chr2_-_60722636 0.74 ENSMUST00000028348.2
ENSMUST00000112517.1
integrin beta 6
chr2_+_30595037 0.74 ENSMUST00000102853.3
CSA-conditional, T cell activation-dependent protein
chr13_+_5861489 0.71 ENSMUST00000000080.6
Kruppel-like factor 6
chr2_+_24345305 0.71 ENSMUST00000114482.1
interleukin 1 receptor antagonist
chr11_+_114851142 0.71 ENSMUST00000133245.1
ENSMUST00000122967.2
G protein-coupled receptor, family C, group 5, member C
chr18_+_69925466 0.70 ENSMUST00000043929.4
coiled-coil domain containing 68
chr1_+_75142775 0.70 ENSMUST00000097694.4
family with sequence similarity 134, member A
chr4_+_102254993 0.70 ENSMUST00000106908.2
phosphodiesterase 4B, cAMP specific
chr6_-_52183828 0.69 ENSMUST00000134831.1
homeobox A3
chr11_+_78499087 0.69 ENSMUST00000017488.4
vitronectin
chr7_+_113765998 0.67 ENSMUST00000046687.9
spondin 1, (f-spondin) extracellular matrix protein
chr14_+_61607455 0.66 ENSMUST00000051184.8
potassium channel regulator
chr19_-_58455161 0.66 ENSMUST00000135730.1
ENSMUST00000152507.1
glial cell line derived neurotrophic factor family receptor alpha 1
chr5_+_90561102 0.65 ENSMUST00000094615.4
RIKEN cDNA 5830473C10 gene
chr2_+_58755177 0.65 ENSMUST00000102755.3
uridine phosphorylase 2
chr8_-_121083085 0.64 ENSMUST00000182264.1
Foxf1 adjacent non-coding developmental regulatory RNA
chr4_-_58499398 0.63 ENSMUST00000107570.1
lysophosphatidic acid receptor 1
chr2_+_158306493 0.63 ENSMUST00000016168.2
ENSMUST00000109491.1
lipopolysaccharide binding protein
chr13_-_12464925 0.62 ENSMUST00000124888.1
lectin, galactose binding, soluble 8
chr3_+_27154020 0.61 ENSMUST00000181124.1
RIKEN cDNA 1700125G22 gene
chr19_+_56461629 0.60 ENSMUST00000178590.1
ENSMUST00000039666.6
pleckstrin homology domain containing, family S member 1
chr7_+_43351378 0.60 ENSMUST00000012798.7
ENSMUST00000122423.1
ENSMUST00000121494.1
sialic acid binding Ig-like lectin 5
chr15_+_4727175 0.59 ENSMUST00000162585.1
complement component 6
chr7_+_19359740 0.59 ENSMUST00000140836.1
protein phosphatase 1, regulatory (inhibitor) subunit 13 like
chr2_-_51972990 0.59 ENSMUST00000145481.1
ENSMUST00000112705.2
N-myc (and STAT) interactor
chr18_-_60501983 0.58 ENSMUST00000042710.6
small integral membrane protein 3
chr3_+_19957037 0.58 ENSMUST00000091309.5
ENSMUST00000108329.1
ENSMUST00000003714.6
ceruloplasmin
chr11_-_99438143 0.58 ENSMUST00000017743.2
keratin 20
chr18_+_37742088 0.58 ENSMUST00000003599.6
protocadherin gamma subfamily A, 9
chr11_-_99993992 0.58 ENSMUST00000105049.1
keratin associated protein 17-1
chr2_-_51973219 0.58 ENSMUST00000028314.2
N-myc (and STAT) interactor
chr1_-_136960427 0.57 ENSMUST00000027649.7
nuclear receptor subfamily 5, group A, member 2
chr11_-_101226414 0.57 ENSMUST00000100417.2
ENSMUST00000107285.1
ENSMUST00000107284.1
enhancer of zeste homolog 1 (Drosophila)
chr2_-_154613425 0.56 ENSMUST00000181369.1
RIKEN cDNA 4930519P11 gene
chr13_+_49582745 0.56 ENSMUST00000065494.7
osteomodulin
chr6_+_134830216 0.56 ENSMUST00000111937.1
cAMP responsive element binding protein-like 2
chr10_+_99263224 0.56 ENSMUST00000020118.4
dual specificity phosphatase 6
chr18_-_84086379 0.55 ENSMUST00000060303.8
teashirt zinc finger family member 1
chr18_+_51117754 0.55 ENSMUST00000116639.2
proline rich 16
chr2_+_58754910 0.55 ENSMUST00000059102.6
uridine phosphorylase 2
chr5_-_103211251 0.54 ENSMUST00000060871.5
ENSMUST00000112846.1
ENSMUST00000170792.1
ENSMUST00000112847.2
mitogen-activated protein kinase 10
chr1_-_156034800 0.54 ENSMUST00000169241.1
torsin A interacting protein 1
chr1_-_166409773 0.54 ENSMUST00000135673.1
ENSMUST00000079972.6
ENSMUST00000169324.1
ENSMUST00000111411.2
ENSMUST00000128861.1
pogo transposable element with KRAB domain
chrX_+_106920618 0.53 ENSMUST00000060576.7
lysophosphatidic acid receptor 4
chrX_+_136707976 0.52 ENSMUST00000055104.5
transcription elongation factor A (SII)-like 1
chr17_+_46161021 0.52 ENSMUST00000024748.7
ENSMUST00000172170.1
GTP binding protein 2
chr5_+_16553488 0.51 ENSMUST00000030683.3
hepatocyte growth factor
chr3_-_46447939 0.51 ENSMUST00000166505.1
poly(A) binding protein, cytoplasmic 4-like
chr19_+_55741810 0.51 ENSMUST00000111657.3
ENSMUST00000061496.9
ENSMUST00000041717.7
ENSMUST00000111662.4
transcription factor 7 like 2, T cell specific, HMG box
chr12_-_31950535 0.50 ENSMUST00000172314.2
high mobility group box transcription factor 1
chrX_-_155623325 0.50 ENSMUST00000038665.5
patched domain containing 1
chr3_+_137867675 0.50 ENSMUST00000090178.5
DnaJ (Hsp40) homolog, subfamily B, member 14
chr5_+_107437908 0.50 ENSMUST00000094541.2
BTB (POZ) domain containing 8
chr9_+_107975529 0.48 ENSMUST00000035216.4
ubiquitin-like modifier activating enzyme 7
chr12_+_77238093 0.48 ENSMUST00000177595.1
ENSMUST00000171770.2
fucosyltransferase 8
chr19_-_37207293 0.47 ENSMUST00000132580.1
ENSMUST00000079754.4
ENSMUST00000136286.1
ENSMUST00000126188.1
ENSMUST00000126781.1
cytoplasmic polyadenylation element binding protein 3
chr7_-_44849075 0.47 ENSMUST00000047085.8
TBC1 domain family, member 17
chr1_-_126830632 0.47 ENSMUST00000112583.1
ENSMUST00000094609.3
NCK-associated protein 5
chr19_+_55741884 0.47 ENSMUST00000111658.3
ENSMUST00000111654.1
transcription factor 7 like 2, T cell specific, HMG box
chr3_-_52104891 0.47 ENSMUST00000121440.1
mastermind like 3 (Drosophila)
chr16_-_22657165 0.47 ENSMUST00000089925.3
diacylglycerol kinase, gamma
chr5_-_35679416 0.47 ENSMUST00000114233.2
HtrA serine peptidase 3
chr3_+_96219858 0.46 ENSMUST00000073115.4
histone cluster 2, H2ab
chr10_+_96616998 0.45 ENSMUST00000038377.7
B cell translocation gene 1, anti-proliferative
chr3_+_19957088 0.45 ENSMUST00000108328.1
ceruloplasmin
chr17_+_46161111 0.44 ENSMUST00000166563.1
GTP binding protein 2
chrX_+_163911401 0.44 ENSMUST00000140845.1
adaptor-related protein complex 1, sigma 2 subunit
chr15_-_5108469 0.44 ENSMUST00000141020.1
caspase recruitment domain family, member 6
chr13_+_113342548 0.44 ENSMUST00000078163.7
cDNA sequence BC067074
chr6_+_142298419 0.43 ENSMUST00000041993.2
islet amyloid polypeptide
chr10_-_33624587 0.42 ENSMUST00000160299.1
ENSMUST00000019920.6
clavesin 2
chrX_+_159708593 0.42 ENSMUST00000080394.6
SH3-domain kinase binding protein 1
chr18_+_36952621 0.41 ENSMUST00000115661.2
protocadherin alpha 2
chr1_+_43445736 0.41 ENSMUST00000086421.5
ENSMUST00000114744.1
non-catalytic region of tyrosine kinase adaptor protein 2
chr11_+_85832551 0.40 ENSMUST00000000095.6
T-box 2
chr8_-_45262012 0.40 ENSMUST00000034064.3
coagulation factor XI
chr13_-_74807913 0.40 ENSMUST00000065629.4
calpastatin
chr6_-_137571007 0.40 ENSMUST00000100841.2
epidermal growth factor receptor pathway substrate 8
chr2_+_24336846 0.40 ENSMUST00000114487.2
interleukin 1 receptor antagonist
chr6_+_134830145 0.39 ENSMUST00000046303.5
cAMP responsive element binding protein-like 2
chr16_-_38294774 0.39 ENSMUST00000023504.4
nuclear receptor subfamily 1, group I, member 2
chr16_-_29378667 0.39 ENSMUST00000143373.1
ENSMUST00000075806.4
ATPase type 13A5
chr1_+_51289106 0.39 ENSMUST00000051572.6
serum deprivation response
chr18_+_21072329 0.38 ENSMUST00000082235.4
meprin 1 beta
chr4_+_43669610 0.38 ENSMUST00000107866.1
transmembrane protein 8B
chr18_-_3281036 0.38 ENSMUST00000049942.6
ENSMUST00000139537.1
ENSMUST00000124747.1
cAMP responsive element modulator
chr9_+_86743641 0.37 ENSMUST00000179574.1
protease, serine, 35
chr9_+_43744399 0.37 ENSMUST00000034510.7
poliovirus receptor-related 1
chr5_-_122989086 0.37 ENSMUST00000046073.9
lysine (K)-specific demethylase 2B
chr6_+_92940572 0.36 ENSMUST00000181145.1
ENSMUST00000181840.1
RIKEN cDNA 9530026P05 gene
chr1_-_157256682 0.36 ENSMUST00000134543.1
RAS protein activator like 2
chr2_-_170427828 0.36 ENSMUST00000013667.2
ENSMUST00000109152.2
ENSMUST00000068137.4
breast carcinoma amplified sequence 1
chr15_+_5185700 0.36 ENSMUST00000081640.5
tetratricopeptide repeat domain 33

Network of associatons between targets according to the STRING database.

First level regulatory network of Foxa2_Foxa1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.3 16.9 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.7 2.9 GO:0015801 aromatic amino acid transport(GO:0015801) tryptophan transport(GO:0015827)
0.7 4.7 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.6 1.8 GO:0061402 positive regulation of transcription from RNA polymerase II promoter in response to acidic pH(GO:0061402)
0.6 3.4 GO:0060455 negative regulation of gastric acid secretion(GO:0060455)
0.6 3.3 GO:0042078 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.5 1.5 GO:0060005 vestibular reflex(GO:0060005)
0.4 1.3 GO:1900106 hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.4 3.5 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.4 2.1 GO:0051919 positive regulation of fibrinolysis(GO:0051919)
0.4 2.0 GO:0098886 modification of dendritic spine(GO:0098886)
0.4 1.2 GO:1902524 positive regulation of protein K48-linked ubiquitination(GO:1902524)
0.3 4.5 GO:0070842 aggresome assembly(GO:0070842)
0.3 1.0 GO:0090004 positive regulation of Golgi to plasma membrane protein transport(GO:0042998) positive regulation of establishment of protein localization to plasma membrane(GO:0090004)
0.3 1.0 GO:0072277 metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277)
0.3 3.5 GO:0015868 purine ribonucleotide transport(GO:0015868)
0.3 2.8 GO:0008228 opsonization(GO:0008228)
0.3 1.8 GO:0033564 anterior/posterior axon guidance(GO:0033564)
0.3 1.5 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.3 0.8 GO:0045415 negative regulation of interleukin-8 biosynthetic process(GO:0045415)
0.2 1.0 GO:0072344 rescue of stalled ribosome(GO:0072344)
0.2 1.2 GO:0009597 detection of virus(GO:0009597)
0.2 1.2 GO:2000660 negative regulation of interleukin-1-mediated signaling pathway(GO:2000660)
0.2 1.9 GO:0051611 regulation of serotonin uptake(GO:0051611)
0.2 0.8 GO:0002740 negative regulation of cytokine secretion involved in immune response(GO:0002740)
0.2 1.3 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.2 0.6 GO:0015920 lipopolysaccharide transport(GO:0015920)
0.2 1.7 GO:0015074 DNA integration(GO:0015074)
0.2 2.0 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.2 0.9 GO:0042536 negative regulation of tumor necrosis factor biosynthetic process(GO:0042536)
0.2 0.6 GO:1990401 embryonic lung development(GO:1990401)
0.2 1.0 GO:0038161 prolactin signaling pathway(GO:0038161)
0.2 0.5 GO:0002182 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
0.2 0.6 GO:1904566 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.2 0.9 GO:0003383 apical constriction(GO:0003383)
0.2 0.9 GO:1904075 regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075)
0.2 3.0 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.1 0.4 GO:0021759 globus pallidus development(GO:0021759)
0.1 1.3 GO:0035947 regulation of gluconeogenesis by regulation of transcription from RNA polymerase II promoter(GO:0035947)
0.1 0.4 GO:0007521 muscle cell fate determination(GO:0007521)
0.1 1.7 GO:0060346 bone trabecula formation(GO:0060346)
0.1 0.4 GO:0001970 positive regulation of activation of membrane attack complex(GO:0001970)
0.1 0.5 GO:0046368 GDP-L-fucose metabolic process(GO:0046368)
0.1 0.6 GO:1901509 regulation of endothelial tube morphogenesis(GO:1901509)
0.1 0.7 GO:0021615 specification of organ position(GO:0010159) glossopharyngeal nerve morphogenesis(GO:0021615)
0.1 1.3 GO:0097421 liver regeneration(GO:0097421)
0.1 0.5 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.1 0.5 GO:0060023 soft palate development(GO:0060023)
0.1 1.3 GO:0032308 positive regulation of prostaglandin secretion(GO:0032308)
0.1 0.4 GO:0097647 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.1 0.5 GO:0007258 JUN phosphorylation(GO:0007258)
0.1 1.2 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.1 0.7 GO:0038044 transforming growth factor-beta secretion(GO:0038044)
0.1 0.3 GO:0002276 basophil activation involved in immune response(GO:0002276)
0.1 0.3 GO:0071895 negative regulation of interleukin-13 production(GO:0032696) odontoblast differentiation(GO:0071895)
0.1 0.6 GO:0002317 plasma cell differentiation(GO:0002317)
0.1 0.4 GO:1903898 positive regulation of translation in response to endoplasmic reticulum stress(GO:0036493) negative regulation of PERK-mediated unfolded protein response(GO:1903898)
0.1 2.6 GO:0008211 glucocorticoid metabolic process(GO:0008211)
0.1 0.4 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.1 0.5 GO:2000544 cell chemotaxis to fibroblast growth factor(GO:0035766) endothelial cell chemotaxis to fibroblast growth factor(GO:0035768) regulation of cell chemotaxis to fibroblast growth factor(GO:1904847) regulation of endothelial cell chemotaxis to fibroblast growth factor(GO:2000544)
0.1 0.5 GO:0032915 positive regulation of transforming growth factor beta2 production(GO:0032915)
0.1 0.9 GO:0061002 negative regulation of dendritic spine morphogenesis(GO:0061002)
0.1 0.4 GO:0021993 initiation of neural tube closure(GO:0021993)
0.1 0.3 GO:0050925 negative regulation of negative chemotaxis(GO:0050925)
0.1 0.9 GO:0015691 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.1 0.6 GO:0061113 pancreas morphogenesis(GO:0061113)
0.1 1.0 GO:0044336 canonical Wnt signaling pathway involved in negative regulation of apoptotic process(GO:0044336)
0.1 0.9 GO:0018298 protein-chromophore linkage(GO:0018298)
0.1 2.2 GO:0046688 response to copper ion(GO:0046688)
0.1 0.6 GO:0042663 regulation of endodermal cell fate specification(GO:0042663)
0.1 2.2 GO:0048268 clathrin coat assembly(GO:0048268)
0.1 0.4 GO:0042738 exogenous drug catabolic process(GO:0042738) xenobiotic transport(GO:0042908)
0.1 0.5 GO:2000271 positive regulation of fibroblast apoptotic process(GO:2000271)
0.1 3.3 GO:0030195 negative regulation of blood coagulation(GO:0030195) negative regulation of hemostasis(GO:1900047)
0.1 0.7 GO:0042473 outer ear morphogenesis(GO:0042473)
0.1 0.3 GO:0007525 somatic muscle development(GO:0007525)
0.1 2.0 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.1 0.4 GO:2000675 negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.1 0.5 GO:0060665 regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling(GO:0060665)
0.1 0.8 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.1 0.2 GO:0010248 establishment or maintenance of transmembrane electrochemical gradient(GO:0010248)
0.1 0.5 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.1 0.3 GO:0061589 calcium activated phosphatidylserine scrambling(GO:0061589)
0.1 0.4 GO:0036438 maintenance of lens transparency(GO:0036438)
0.1 0.3 GO:0050847 progesterone receptor signaling pathway(GO:0050847)
0.1 0.2 GO:0070104 negative regulation of interleukin-6-mediated signaling pathway(GO:0070104)
0.1 2.3 GO:0060706 cell differentiation involved in embryonic placenta development(GO:0060706)
0.1 1.1 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.0 2.0 GO:0046834 lipid phosphorylation(GO:0046834)
0.0 0.7 GO:0010745 negative regulation of macrophage derived foam cell differentiation(GO:0010745)
0.0 0.9 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.5 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.2 GO:0061146 Peyer's patch morphogenesis(GO:0061146)
0.0 0.5 GO:0070389 chaperone cofactor-dependent protein refolding(GO:0070389)
0.0 0.1 GO:0019478 D-amino acid catabolic process(GO:0019478)
0.0 0.1 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.0 0.2 GO:1903849 regulation of aorta morphogenesis(GO:1903847) positive regulation of aorta morphogenesis(GO:1903849)
0.0 0.3 GO:0030644 cellular chloride ion homeostasis(GO:0030644)
0.0 0.7 GO:1903817 negative regulation of delayed rectifier potassium channel activity(GO:1902260) negative regulation of voltage-gated potassium channel activity(GO:1903817)
0.0 0.1 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.0 0.3 GO:0021527 spinal cord association neuron differentiation(GO:0021527)
0.0 0.1 GO:0090154 apoptotic process involved in heart morphogenesis(GO:0003278) positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.0 0.3 GO:0071763 nuclear membrane organization(GO:0071763)
0.0 3.0 GO:0030216 keratinocyte differentiation(GO:0030216)
0.0 0.6 GO:0045109 intermediate filament organization(GO:0045109)
0.0 0.1 GO:0048014 Tie signaling pathway(GO:0048014)
0.0 0.1 GO:0035470 positive regulation of vascular wound healing(GO:0035470) regulation of vascular wound healing(GO:0061043)
0.0 0.1 GO:0060684 epithelial-mesenchymal cell signaling(GO:0060684)
0.0 0.1 GO:0030043 actin filament fragmentation(GO:0030043)
0.0 0.1 GO:0061343 cell adhesion involved in heart morphogenesis(GO:0061343)
0.0 0.6 GO:0003215 cardiac right ventricle morphogenesis(GO:0003215)
0.0 0.2 GO:1904220 regulation of serine C-palmitoyltransferase activity(GO:1904220)
0.0 0.8 GO:0030212 hyaluronan metabolic process(GO:0030212)
0.0 0.5 GO:0021794 thalamus development(GO:0021794)
0.0 0.5 GO:0045793 positive regulation of cell size(GO:0045793)
0.0 0.2 GO:0031179 peptide modification(GO:0031179)
0.0 0.1 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.0 0.1 GO:0002760 positive regulation of antimicrobial peptide production(GO:0002225) positive regulation of antimicrobial humoral response(GO:0002760) regulation of antimicrobial peptide production(GO:0002784) regulation of antibacterial peptide production(GO:0002786) positive regulation of antibacterial peptide production(GO:0002803)
0.0 1.1 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.0 0.2 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 0.5 GO:1903846 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.0 0.2 GO:0042048 olfactory behavior(GO:0042048)
0.0 0.1 GO:0071896 protein localization to adherens junction(GO:0071896)
0.0 0.1 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.0 2.1 GO:0050680 negative regulation of epithelial cell proliferation(GO:0050680)
0.0 0.1 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.0 0.1 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.0 0.4 GO:0019433 triglyceride catabolic process(GO:0019433)
0.0 0.1 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028) positive regulation of glycogen (starch) synthase activity(GO:2000467)
0.0 0.1 GO:0035524 proline transmembrane transport(GO:0035524)
0.0 2.4 GO:0042060 wound healing(GO:0042060)
0.0 0.1 GO:0046909 intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445)
0.0 0.0 GO:1901668 regulation of superoxide dismutase activity(GO:1901668)
0.0 2.5 GO:0007596 blood coagulation(GO:0007596)
0.0 0.6 GO:0030500 regulation of bone mineralization(GO:0030500)
0.0 0.0 GO:1904868 pre-B cell allelic exclusion(GO:0002331) signal transduction involved in G2 DNA damage checkpoint(GO:0072425) signal transduction involved in mitotic G2 DNA damage checkpoint(GO:0072434) telomerase catalytic core complex assembly(GO:1904868) regulation of telomerase catalytic core complex assembly(GO:1904882) positive regulation of telomerase catalytic core complex assembly(GO:1904884)
0.0 0.1 GO:0007343 egg activation(GO:0007343)
0.0 0.2 GO:0033033 negative regulation of myeloid cell apoptotic process(GO:0033033)
0.0 0.2 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 0.1 GO:0031069 hair follicle morphogenesis(GO:0031069)
0.0 0.9 GO:0042147 retrograde transport, endosome to Golgi(GO:0042147)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
2.2 17.2 GO:0005579 membrane attack complex(GO:0005579)
0.5 3.0 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.3 2.3 GO:1990357 terminal web(GO:1990357)
0.3 2.0 GO:0097444 spine apparatus(GO:0097444)
0.2 0.7 GO:0034685 integrin alphav-beta6 complex(GO:0034685)
0.2 0.6 GO:0044279 other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
0.2 3.7 GO:0005922 connexon complex(GO:0005922)
0.2 1.2 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.2 0.8 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.1 1.2 GO:0045098 type III intermediate filament(GO:0045098)
0.1 1.6 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.1 0.9 GO:0033269 internode region of axon(GO:0033269)
0.1 0.9 GO:0035867 alphav-beta3 integrin-IGF-1-IGF1R complex(GO:0035867)
0.1 0.7 GO:0048237 rough endoplasmic reticulum lumen(GO:0048237)
0.1 2.4 GO:0045095 keratin filament(GO:0045095)
0.1 2.0 GO:0000930 gamma-tubulin complex(GO:0000930)
0.1 2.7 GO:0005771 multivesicular body(GO:0005771)
0.1 0.2 GO:0005900 oncostatin-M receptor complex(GO:0005900)
0.0 2.3 GO:0046658 anchored component of plasma membrane(GO:0046658)
0.0 0.3 GO:0001652 granular component(GO:0001652)
0.0 0.2 GO:0017059 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.5 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.4 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.5 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.4 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.2 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.0 1.8 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.0 GO:0016939 kinesin II complex(GO:0016939)
0.0 0.3 GO:0032426 stereocilium tip(GO:0032426)
0.0 0.1 GO:0097025 MPP7-DLG1-LIN7 complex(GO:0097025)
0.0 0.3 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.4 GO:0030904 retromer complex(GO:0030904)
0.0 0.6 GO:0005882 intermediate filament(GO:0005882)
0.0 1.5 GO:0005604 basement membrane(GO:0005604)
0.0 16.2 GO:0005615 extracellular space(GO:0005615)
0.0 0.8 GO:0001750 photoreceptor outer segment(GO:0001750)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.2 8.6 GO:0004556 alpha-amylase activity(GO:0004556)
1.0 4.0 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.6 1.8 GO:0015182 L-asparagine transmembrane transporter activity(GO:0015182)
0.4 2.9 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.4 1.2 GO:0045353 interleukin-1, Type II receptor binding(GO:0005151) interleukin-1 receptor antagonist activity(GO:0005152) interleukin-1 Type I receptor antagonist activity(GO:0045352) interleukin-1 Type II receptor antagonist activity(GO:0045353)
0.4 2.6 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.3 3.9 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.3 2.6 GO:0015379 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.3 2.2 GO:0032051 clathrin light chain binding(GO:0032051)
0.3 6.6 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.3 2.0 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.2 1.2 GO:0004850 uridine phosphorylase activity(GO:0004850)
0.2 0.7 GO:0005118 sevenless binding(GO:0005118)
0.2 3.5 GO:0005243 gap junction channel activity(GO:0005243)
0.2 1.1 GO:0030292 protein tyrosine kinase inhibitor activity(GO:0030292)
0.2 0.8 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
0.2 1.0 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.2 1.0 GO:0004925 prolactin receptor activity(GO:0004925)
0.2 0.8 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.1 0.9 GO:0005173 stem cell factor receptor binding(GO:0005173)
0.1 1.1 GO:0071253 connexin binding(GO:0071253)
0.1 0.5 GO:0008859 exoribonuclease II activity(GO:0008859)
0.1 0.5 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.1 1.3 GO:0070700 BMP receptor binding(GO:0070700)
0.1 2.3 GO:0070016 armadillo repeat domain binding(GO:0070016)
0.1 0.6 GO:0071723 lipopeptide binding(GO:0071723)
0.1 0.3 GO:0035651 AP-3 adaptor complex binding(GO:0035651)
0.1 1.4 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.1 0.5 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.1 1.2 GO:0022889 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.1 0.4 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.1 2.7 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.1 0.6 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.1 3.6 GO:0005044 scavenger receptor activity(GO:0005044)
0.1 0.2 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.1 0.9 GO:0019865 immunoglobulin binding(GO:0019865)
0.1 1.3 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.1 0.3 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.1 2.0 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.1 0.2 GO:0004915 interleukin-6 receptor activity(GO:0004915) leukemia inhibitory factor receptor activity(GO:0004923) interleukin-6 binding(GO:0019981)
0.1 0.2 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1 0.2 GO:0016842 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced ascorbate as one donor, and incorporation of one atom of oxygen(GO:0016715) amidine-lyase activity(GO:0016842)
0.0 1.0 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 4.7 GO:0005179 hormone activity(GO:0005179)
0.0 2.1 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.5 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.1 GO:0003884 D-amino-acid oxidase activity(GO:0003884)
0.0 5.2 GO:0005178 integrin binding(GO:0005178)
0.0 0.4 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.6 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.5 GO:0008417 fucosyltransferase activity(GO:0008417)
0.0 0.4 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.0 0.4 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.0 0.5 GO:0035005 1-phosphatidylinositol-4-phosphate 3-kinase activity(GO:0035005)
0.0 0.2 GO:0008131 primary amine oxidase activity(GO:0008131)
0.0 0.5 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.2 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.0 0.5 GO:0042056 chemoattractant activity(GO:0042056)
0.0 0.9 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.8 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.0 0.3 GO:0008046 axon guidance receptor activity(GO:0008046)
0.0 0.3 GO:1990405 protein antigen binding(GO:1990405)
0.0 0.5 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.1 GO:0004087 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.0 1.1 GO:0005109 frizzled binding(GO:0005109)
0.0 0.2 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.0 1.2 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 0.2 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.5 GO:0005520 insulin-like growth factor binding(GO:0005520)
0.0 1.0 GO:0070888 E-box binding(GO:0070888)
0.0 0.7 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.4 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.3 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.9 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.3 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.0 0.1 GO:0031013 troponin I binding(GO:0031013)
0.0 2.0 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.1 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.0 0.0 GO:0004677 DNA-dependent protein kinase activity(GO:0004677)
0.0 0.3 GO:0005521 lamin binding(GO:0005521)
0.0 0.6 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.1 GO:0032027 myosin light chain binding(GO:0032027)
0.0 0.5 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.5 GO:0050699 WW domain binding(GO:0050699)
0.0 0.2 GO:0001618 virus receptor activity(GO:0001618)
0.0 0.1 GO:0043522 leucine zipper domain binding(GO:0043522)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 8.3 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 0.8 ST DIFFERENTIATION PATHWAY IN PC12 CELLS Differentiation Pathway in PC12 Cells; this is a specific case of PAC1 Receptor Pathway.
0.1 1.3 PID ALK2 PATHWAY ALK2 signaling events
0.1 3.6 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.1 1.3 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 4.0 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.1 0.9 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.0 1.8 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.9 PID INTEGRIN5 PATHWAY Beta5 beta6 beta7 and beta8 integrin cell surface interactions
0.0 2.9 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 1.7 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 1.0 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 1.0 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.5 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 1.0 PID PTP1B PATHWAY Signaling events mediated by PTP1B
0.0 5.2 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 0.4 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 1.0 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 2.3 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.0 0.7 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 3.8 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.1 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.3 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 0.5 ST GRANULE CELL SURVIVAL PATHWAY Granule Cell Survival Pathway is a specific case of more general PAC1 Receptor Pathway.
0.0 4.5 NABA SECRETED FACTORS Genes encoding secreted soluble factors
0.0 1.0 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.0 0.7 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.5 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.4 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 16.5 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.3 5.4 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.2 1.0 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.2 3.8 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.2 1.8 REACTOME ROLE OF SECOND MESSENGERS IN NETRIN1 SIGNALING Genes involved in Role of second messengers in netrin-1 signaling
0.2 2.0 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.1 2.9 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.1 1.8 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.1 1.2 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.1 1.0 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.1 0.6 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.1 0.6 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 1.0 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.5 REACTOME FGFR4 LIGAND BINDING AND ACTIVATION Genes involved in FGFR4 ligand binding and activation
0.0 0.5 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.8 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.0 1.4 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 1.4 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.9 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 1.3 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.4 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 1.6 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.5 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.4 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.5 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.4 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.9 REACTOME SYNTHESIS OF PIPS AT THE PLASMA MEMBRANE Genes involved in Synthesis of PIPs at the plasma membrane
0.0 0.5 REACTOME N GLYCAN ANTENNAE ELONGATION IN THE MEDIAL TRANS GOLGI Genes involved in N-glycan antennae elongation in the medial/trans-Golgi
0.0 0.2 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 1.5 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.7 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 0.1 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.0 0.0 REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1 Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.0 0.5 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.4 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.3 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 2.3 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.5 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling