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2D miR_HR1_12

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Results for Nkx2-2

Z-value: 1.01

Motif logo

Transcription factors associated with Nkx2-2

Gene Symbol Gene ID Gene Info
ENSMUSG00000027434.10 NK2 homeobox 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Nkx2-2mm10_v2_chr2_-_147186389_1471864130.811.5e-03Click!

Activity profile of Nkx2-2 motif

Sorted Z-values of Nkx2-2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr10_+_88091070 2.03 ENSMUST00000048621.7
pro-melanin-concentrating hormone
chr11_+_78301529 1.66 ENSMUST00000045026.3
sperm associated antigen 5
chrX_+_164980592 1.61 ENSMUST00000101082.4
ENSMUST00000167446.1
ENSMUST00000057150.6
Fanconi anemia, complementation group B
chr17_-_34628380 1.35 ENSMUST00000167097.2
palmitoyl-protein thioesterase 2
chrX_+_9885622 1.35 ENSMUST00000067529.2
ENSMUST00000086165.3
synaptotagmin-like 5
chr2_+_69897255 1.22 ENSMUST00000131553.1
ubiquitin protein ligase E3 component n-recognin 3
chr19_-_11266122 1.09 ENSMUST00000169159.1
membrane-spanning 4-domains, subfamily A, member 1
chr5_-_88527841 1.09 ENSMUST00000087033.3
immunoglobulin joining chain
chr17_-_34628005 1.06 ENSMUST00000166040.2
palmitoyl-protein thioesterase 2
chr13_+_51645232 0.97 ENSMUST00000075853.5
CDC28 protein kinase regulatory subunit 2
chr9_-_96719549 0.92 ENSMUST00000128269.1
zinc finger and BTB domain containing 38
chr3_+_10366903 0.88 ENSMUST00000029049.5
charged multivesicular body protein 4C
chr18_+_4993795 0.84 ENSMUST00000153016.1
supervillin
chr2_+_174076296 0.81 ENSMUST00000155000.1
ENSMUST00000134876.1
ENSMUST00000147038.1
syntaxin 16
chr19_-_40402267 0.80 ENSMUST00000099467.3
ENSMUST00000099466.3
ENSMUST00000165212.1
ENSMUST00000165469.1
sorbin and SH3 domain containing 1
chr5_+_110839973 0.76 ENSMUST00000066160.1
checkpoint kinase 2
chr3_-_33143227 0.74 ENSMUST00000108219.1
peroxisomal biogenesis factor 5-like
chr3_+_138143888 0.73 ENSMUST00000161141.1
tRNA methyltransferase 10A
chr9_+_51213683 0.71 ENSMUST00000034554.7
POU domain, class 2, associating factor 1
chr3_+_76075583 0.71 ENSMUST00000160261.1
follistatin-like 5
chr2_-_140170528 0.70 ENSMUST00000046030.7
ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae)
chr6_-_59426279 0.69 ENSMUST00000051065.4
GPRIN family member 3
chr11_-_90390895 0.69 ENSMUST00000004051.7
hepatic leukemia factor
chr3_+_138143846 0.68 ENSMUST00000159481.1
tRNA methyltransferase 10A
chr17_-_34627365 0.68 ENSMUST00000064953.8
ENSMUST00000170345.1
ENSMUST00000171121.2
ENSMUST00000168391.2
ENSMUST00000169067.2
palmitoyl-protein thioesterase 2
chr13_-_8858762 0.67 ENSMUST00000176329.1
WD repeat domain 37
chr2_+_3704787 0.66 ENSMUST00000115054.2
family with sequence similarity 107, member B
chr11_+_48800357 0.64 ENSMUST00000020640.7
guanine nucleotide binding protein (G protein), beta polypeptide 2 like 1
chr1_-_152386589 0.64 ENSMUST00000162371.1
tRNA splicing endonuclease 15 homolog (S. cerevisiae)
chr6_-_120357342 0.63 ENSMUST00000163827.1
coiled-coil domain containing 77
chr3_+_65528457 0.62 ENSMUST00000130705.1
TCDD-inducible poly(ADP-ribose) polymerase
chr11_+_97685903 0.61 ENSMUST00000107583.2
CDGSH iron sulfur domain 3
chr17_+_71616215 0.61 ENSMUST00000047086.9
WD repeat domain 43
chr6_+_8520008 0.61 ENSMUST00000162567.1
ENSMUST00000161217.1
glucocorticoid induced transcript 1
chr5_-_3596071 0.61 ENSMUST00000121877.1
RNA binding motif protein 48
chr19_-_5796924 0.60 ENSMUST00000174808.1
metastasis associated lung adenocarcinoma transcript 1 (non-coding RNA)
chr2_-_153015331 0.58 ENSMUST00000028972.8
p53 and DNA damage regulated 1
chr17_-_15564322 0.58 ENSMUST00000147532.1
PR domain containing 9
chr2_+_71873224 0.58 ENSMUST00000006669.5
pyruvate dehydrogenase kinase, isoenzyme 1
chr1_-_65123108 0.56 ENSMUST00000050047.3
ENSMUST00000148020.1
RIKEN cDNA D630023F18 gene
chr15_-_102350692 0.55 ENSMUST00000041208.7
achalasia, adrenocortical insufficiency, alacrimia
chr3_+_138143799 0.54 ENSMUST00000159622.1
tRNA methyltransferase 10A
chr6_+_88465409 0.53 ENSMUST00000032165.9
RuvB-like protein 1
chr1_-_176807124 0.53 ENSMUST00000057037.7
centrosomal protein 170
chr3_-_33082004 0.52 ENSMUST00000108225.3
peroxisomal biogenesis factor 5-like
chr9_-_96719404 0.51 ENSMUST00000140121.1
zinc finger and BTB domain containing 38
chrX_+_37265338 0.50 ENSMUST00000115194.3
reproductive homeobox 4A
chrX_+_73673150 0.48 ENSMUST00000033752.7
ENSMUST00000114467.2
solute carrier family 6 (neurotransmitter transporter, creatine), member 8
chr6_-_120357440 0.48 ENSMUST00000112703.1
coiled-coil domain containing 77
chr11_-_121519326 0.48 ENSMUST00000092298.5
zinc finger protein 750
chr17_+_46496753 0.47 ENSMUST00000046497.6
2'-deoxynucleoside 5'-phosphate N-hydrolase 1
chr4_+_11321930 0.47 ENSMUST00000181105.1
predicted gene, 26663
chr14_-_68533689 0.47 ENSMUST00000022640.7
a disintegrin and metallopeptidase domain 7
chr4_+_155891822 0.46 ENSMUST00000105584.3
ENSMUST00000079031.5
ArfGAP with coiled-coil, ankyrin repeat and PH domains 3
chr6_+_14901344 0.46 ENSMUST00000115477.1
forkhead box P2
chr7_-_80403315 0.46 ENSMUST00000147150.1
furin (paired basic amino acid cleaving enzyme)
chr17_-_83631892 0.46 ENSMUST00000051482.1
potassium voltage-gated channel, subfamily G, member 3
chr4_+_95579417 0.45 ENSMUST00000043335.4
FGGY carbohydrate kinase domain containing
chr16_-_16527364 0.45 ENSMUST00000069284.7
FYVE, RhoGEF and PH domain containing 4
chr12_-_100899436 0.45 ENSMUST00000053668.3
G protein-coupled receptor 68
chr2_-_73453918 0.44 ENSMUST00000102679.1
WAS/WASL interacting protein family, member 1
chr14_+_47663756 0.44 ENSMUST00000022391.7
kinectin 1
chr10_+_57645834 0.43 ENSMUST00000177325.1
protein kinase inhibitor beta, cAMP dependent, testis specific
chr9_+_72438519 0.43 ENSMUST00000184604.1
meiosis-specific nuclear structural protein 1
chr6_-_120357422 0.43 ENSMUST00000032283.5
coiled-coil domain containing 77
chr12_+_38781093 0.43 ENSMUST00000161513.1
ets variant gene 1
chr2_+_30807826 0.43 ENSMUST00000041830.3
ENSMUST00000152374.1
N-terminal Xaa-Pro-Lys N-methyltransferase 1
chr7_-_43533171 0.43 ENSMUST00000004728.5
ENSMUST00000039861.5
CD33 antigen
chr2_+_140170641 0.42 ENSMUST00000044825.4
NADH dehydrogenase (ubiquinone) complex I, assembly factor 5
chr11_-_71004387 0.42 ENSMUST00000124464.1
ENSMUST00000108527.1
DEAH (Asp-Glu-Ala-His) box polypeptide 33
chr3_-_142169311 0.42 ENSMUST00000106230.1
bone morphogenetic protein receptor, type 1B
chr6_+_29859686 0.41 ENSMUST00000134438.1
S-adenosylhomocysteine hydrolase-like 2
chr10_+_57645861 0.39 ENSMUST00000177473.1
protein kinase inhibitor beta, cAMP dependent, testis specific
chr6_+_137754529 0.39 ENSMUST00000087675.6
2-deoxyribose-5-phosphate aldolase homolog (C. elegans)
chr1_-_135688094 0.39 ENSMUST00000112103.1
neuron navigator 1
chr17_-_32822200 0.39 ENSMUST00000179695.1
zinc finger protein 799
chr8_+_123411424 0.39 ENSMUST00000071134.3
tubulin, beta 3 class III
chr13_+_14630237 0.38 ENSMUST00000178289.1
ENSMUST00000038690.4
expressed sequence AW209491
chr6_-_3494587 0.38 ENSMUST00000049985.8
HEPACAM family member 2
chr1_-_152386675 0.37 ENSMUST00000015124.8
tRNA splicing endonuclease 15 homolog (S. cerevisiae)
chr5_-_110839575 0.36 ENSMUST00000145318.1
HscB iron-sulfur cluster co-chaperone homolog (E. coli)
chr10_+_23920356 0.36 ENSMUST00000051532.4
trace amine-associated receptor 1
chr3_+_62419668 0.35 ENSMUST00000161057.1
Rho guanine nucleotide exchange factor (GEF) 26
chr17_+_29614800 0.35 ENSMUST00000162588.1
ring finger protein 8
chr4_+_95579463 0.33 ENSMUST00000150830.1
ENSMUST00000134012.2
FGGY carbohydrate kinase domain containing
chr13_-_85127514 0.33 ENSMUST00000179230.1
predicted gene 4076
chr2_-_26380600 0.33 ENSMUST00000114115.2
ENSMUST00000035427.4
small nuclear RNA activating complex, polypeptide 4
chr3_-_130730375 0.33 ENSMUST00000079085.6
ribosomal protein L34
chr16_-_85550417 0.33 ENSMUST00000175700.1
ENSMUST00000114174.2
cysteine and tyrosine-rich protein 1
chr3_+_104865062 0.32 ENSMUST00000123876.1
suppression of tumorigenicity 7-like
chr8_+_123332676 0.32 ENSMUST00000010298.6
spire homolog 2 (Drosophila)
chr17_+_28691419 0.32 ENSMUST00000124886.1
mitogen-activated protein kinase 14
chr11_+_66956620 0.32 ENSMUST00000150220.1
RIKEN cDNA 9130409J20 gene
chr14_+_24490678 0.31 ENSMUST00000169826.1
ENSMUST00000112384.3
ribosomal protein S24
chr1_-_39577340 0.30 ENSMUST00000062525.5
ring finger protein 149
chr14_-_59395381 0.29 ENSMUST00000166912.2
PHD finger protein 11C
chr10_-_13388830 0.29 ENSMUST00000079698.5
phosphatase and actin regulator 2
chr10_-_18785011 0.28 ENSMUST00000055107.6
predicted gene 4922
chr2_+_23069210 0.28 ENSMUST00000155602.1
acyl-Coenzyme A binding domain containing 5
chrX_+_106027259 0.28 ENSMUST00000113557.1
ATPase, Cu++ transporting, alpha polypeptide
chr11_+_57518657 0.28 ENSMUST00000108849.1
ENSMUST00000020830.7
microfibrillar-associated protein 3
chr3_+_94443315 0.28 ENSMUST00000029786.7
ENSMUST00000098876.3
mitochondrial ribosomal protein L9
chr10_-_93891141 0.28 ENSMUST00000180840.1
methionine aminopeptidase 2
chr6_-_38046994 0.27 ENSMUST00000096040.4
SV2 related protein homolog (rat)-like
chr4_+_103313806 0.26 ENSMUST00000035780.3
OMA1 homolog, zinc metallopeptidase (S. cerevisiae)
chr1_-_166002613 0.26 ENSMUST00000177358.1
ENSMUST00000160908.1
ENSMUST00000027850.8
ENSMUST00000160260.2
POU domain, class 2, transcription factor 1
chr11_+_3649759 0.26 ENSMUST00000140242.1
microrchidia 2A
chr11_+_119913423 0.26 ENSMUST00000132197.1
charged multivesicular body protein 6
chr4_-_138913915 0.25 ENSMUST00000097830.3
OTU domain containing 3
chr3_-_146770603 0.25 ENSMUST00000106138.1
protein kinase, cAMP dependent, catalytic, beta
chr10_+_19951055 0.25 ENSMUST00000152533.1
mitogen-activated protein kinase kinase kinase 5
chr1_+_86064619 0.25 ENSMUST00000027432.8
proteasome (prosome, macropain) 26S subunit, non-ATPase, 1
chrX_+_164269371 0.25 ENSMUST00000145412.1
ENSMUST00000033749.7
pirin
chr1_-_85736525 0.24 ENSMUST00000064788.7
RIKEN cDNA A630001G21 gene
chr16_-_97763449 0.24 ENSMUST00000113743.1
receptor-interacting serine-threonine kinase 4
chrX_+_107149580 0.23 ENSMUST00000137107.1
ENSMUST00000067249.2
RIKEN cDNA A630033H20 gene
chr8_+_41239718 0.23 ENSMUST00000045218.7
pericentriolar material 1
chrX_+_56609751 0.23 ENSMUST00000144068.1
solute carrier family 9 (sodium/hydrogen exchanger), member 6
chr17_+_43568475 0.23 ENSMUST00000167418.1
phospholipase A2, group VII (platelet-activating factor acetylhydrolase, plasma)
chr2_+_52072823 0.21 ENSMUST00000112693.2
ENSMUST00000069794.5
Rap1 interacting factor 1 homolog (yeast)
chr7_+_19345135 0.21 ENSMUST00000160369.1
excision repair cross-complementing rodent repair deficiency, complementation group 1
chr1_-_139377094 0.21 ENSMUST00000131586.1
ENSMUST00000145244.1
crumbs homolog 1 (Drosophila)
chr4_-_155891701 0.21 ENSMUST00000097737.4
pseudouridylate synthase-like 1
chrX_+_106027300 0.21 ENSMUST00000055941.6
ATPase, Cu++ transporting, alpha polypeptide
chr4_+_102986343 0.21 ENSMUST00000030248.5
ENSMUST00000125417.1
Tctex1 domain containing 1
chr3_-_146770218 0.20 ENSMUST00000106137.1
protein kinase, cAMP dependent, catalytic, beta
chrM_+_11734 0.20 ENSMUST00000082418.1
mitochondrially encoded NADH dehydrogenase 5
chr11_-_57518596 0.20 ENSMUST00000108850.1
ENSMUST00000020831.6
family with sequence similarity 114, member A2
chr5_-_30073554 0.20 ENSMUST00000026846.6
thymidylate synthase
chr1_+_72711259 0.20 ENSMUST00000059980.9
ribosomal protein L37a
chr12_-_112860886 0.20 ENSMUST00000021729.7
G protein-coupled receptor 132
chr3_+_138143483 0.20 ENSMUST00000162864.1
tRNA methyltransferase 10A
chrX_+_107149454 0.20 ENSMUST00000125676.1
ENSMUST00000180182.1
RIKEN cDNA A630033H20 gene
chr4_-_129640959 0.19 ENSMUST00000132217.1
ENSMUST00000130017.1
ENSMUST00000154105.1
taxilin alpha
chr2_+_62664279 0.19 ENSMUST00000028257.2
grancalcin
chr1_+_173673651 0.19 ENSMUST00000085876.4
pyrin domain containing 3
chr9_+_72438534 0.18 ENSMUST00000034746.8
meiosis-specific nuclear structural protein 1
chr9_+_105053239 0.18 ENSMUST00000035177.8
ENSMUST00000149243.1
mitochondrial ribosomal protein L3
chr7_+_29768552 0.18 ENSMUST00000032802.4
zinc finger protein 84
chr4_+_99272671 0.18 ENSMUST00000094956.1
predicted gene 10305
chr3_+_65528404 0.18 ENSMUST00000047906.3
TCDD-inducible poly(ADP-ribose) polymerase
chr15_-_73184840 0.18 ENSMUST00000044113.10
argonaute RISC catalytic subunit 2
chr3_+_76593550 0.18 ENSMUST00000162471.1
follistatin-like 5
chr6_+_86078070 0.18 ENSMUST00000032069.5
adducin 2 (beta)
chr2_+_163661495 0.18 ENSMUST00000135537.1
protein kinase inhibitor, gamma
chr2_+_32535724 0.18 ENSMUST00000133366.1
family with sequence similarity 102, member A
chrX_+_21714896 0.18 ENSMUST00000033414.7
solute carrier family 6 (neurotransmitter transporter), member 14
chr18_-_6241470 0.17 ENSMUST00000163210.1
kinesin family member 5B
chr16_+_14705832 0.17 ENSMUST00000023356.6
snail homolog 2 (Drosophila)
chr6_+_85451488 0.17 ENSMUST00000032078.6
chaperonin containing Tcp1, subunit 7 (eta)
chr15_-_8710734 0.17 ENSMUST00000005493.7
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr14_-_104522615 0.17 ENSMUST00000022716.2
ring finger protein 219
chr5_+_105876532 0.16 ENSMUST00000150440.1
ENSMUST00000031227.4
zinc finger protein 326
chr3_-_142169196 0.16 ENSMUST00000098568.1
bone morphogenetic protein receptor, type 1B
chr12_-_83487708 0.16 ENSMUST00000177959.1
ENSMUST00000178756.1
D4, zinc and double PHD fingers, family 3
chr6_+_5390387 0.16 ENSMUST00000183358.1
ankyrin repeat and SOCS box-containing 4
chr5_+_136919137 0.16 ENSMUST00000181045.1
RIKEN cDNA 4933404O12 gene
chr8_+_40354303 0.16 ENSMUST00000136835.1
mitochondrial calcium uptake family, member 3
chr6_+_145953429 0.16 ENSMUST00000111701.1
sarcospan
chr1_-_139377041 0.16 ENSMUST00000059825.5
crumbs homolog 1 (Drosophila)
chr3_+_138143429 0.16 ENSMUST00000040321.6
tRNA methyltransferase 10A
chr15_+_81744848 0.16 ENSMUST00000109554.1
zinc finger CCCH type containing 7B
chr1_+_79776018 0.15 ENSMUST00000027464.8
mitochondrial ribosomal protein L44
chr9_+_74976096 0.15 ENSMUST00000081746.5
family with sequence similarity 214, member A
chr4_-_43010226 0.15 ENSMUST00000030165.4
Fanconi anemia, complementation group G
chr19_-_29753600 0.15 ENSMUST00000175764.1
RIKEN cDNA 9930021J03 gene
chr1_-_9748376 0.14 ENSMUST00000057438.6
valosin containing protein (p97)/p47 complex interacting protein 1
chr5_-_69592274 0.14 ENSMUST00000174233.1
ENSMUST00000120789.1
ENSMUST00000166298.1
glucosamine-6-phosphate deaminase 2
chr2_+_21205719 0.14 ENSMUST00000054591.3
ENSMUST00000102952.1
ENSMUST00000138965.1
ENSMUST00000138914.1
ENSMUST00000102951.1
threonine synthase-like 1 (bacterial)
chr9_+_75037809 0.14 ENSMUST00000167885.1
cAMP-regulated phosphoprotein 19
chr12_+_73901370 0.14 ENSMUST00000110461.1
hypoxia inducible factor 1, alpha subunit
chr8_-_36953139 0.14 ENSMUST00000179501.1
deleted in liver cancer 1
chr11_+_88973928 0.14 ENSMUST00000036649.4
ENSMUST00000107898.3
coilin
chr9_-_119322421 0.14 ENSMUST00000040853.4
oxidative-stress responsive 1
chrX_-_101420206 0.14 ENSMUST00000118092.1
zinc finger, MYM-type 3
chr8_+_105880875 0.14 ENSMUST00000040254.9
ENSMUST00000119261.1
enhancer of mRNA decapping 4
chr14_-_54686060 0.12 ENSMUST00000125265.1
apoptotic chromatin condensation inducer 1
chr18_+_23753708 0.12 ENSMUST00000115830.1
microtubule-associated protein, RP/EB family, member 2
chr15_-_10470490 0.12 ENSMUST00000136591.1
DnaJ (Hsp40) homolog, subfamily C, member 21
chr1_+_179961110 0.12 ENSMUST00000076687.5
ENSMUST00000097450.3
CDC42 binding protein kinase alpha
chr2_+_35691893 0.12 ENSMUST00000065001.5
disabled 2 interacting protein
chr3_+_32515295 0.11 ENSMUST00000029203.7
zinc finger protein 639
chrX_+_6415736 0.11 ENSMUST00000143641.3
shroom family member 4
chr13_-_29855630 0.11 ENSMUST00000091674.5
ENSMUST00000006353.7
CDK5 regulatory subunit associated protein 1-like 1
chr5_-_145191566 0.11 ENSMUST00000037056.8
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F2
chr9_+_75410145 0.11 ENSMUST00000180533.1
ENSMUST00000180574.1
RIKEN cDNA 4933433G15 gene
chr5_-_145191511 0.11 ENSMUST00000161845.1
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F2
chr5_+_87925579 0.11 ENSMUST00000001667.6
ENSMUST00000113267.1
casein kappa
chr1_-_52953179 0.11 ENSMUST00000114492.1
RIKEN cDNA 1700019D03 gene
chr9_+_106170918 0.10 ENSMUST00000020490.5
WD repeat domain containing 82
chr13_-_21753851 0.10 ENSMUST00000074752.2
histone cluster 1, H2ak
chr11_-_56040985 0.10 ENSMUST00000037682.2
neuromedin U receptor 2
chrX_+_75382384 0.10 ENSMUST00000033541.4
FUN14 domain containing 2
chr6_-_41704339 0.10 ENSMUST00000031899.8
Kell blood group
chrM_+_9452 0.10 ENSMUST00000082411.1
mitochondrially encoded NADH dehydrogenase 3
chr13_-_19732929 0.10 ENSMUST00000151029.1
RIKEN cDNA A530099J19 gene
chr4_+_125029992 0.10 ENSMUST00000030684.7
guanine nucleotide binding protein-like 2 (nucleolar)
chr6_+_122990367 0.10 ENSMUST00000079379.2
C-type lectin domain family 4, member a4
chr10_-_54075702 0.10 ENSMUST00000105470.1
mannosidase 1, alpha
chr11_+_119913802 0.10 ENSMUST00000026434.6
ENSMUST00000124199.1
charged multivesicular body protein 6

Network of associatons between targets according to the STRING database.

First level regulatory network of Nkx2-2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.0 GO:0046005 positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
0.4 1.7 GO:0090235 regulation of metaphase plate congression(GO:0090235)
0.4 1.6 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
0.3 1.2 GO:0071596 ubiquitin-dependent protein catabolic process via the N-end rule pathway(GO:0071596)
0.3 0.9 GO:0044878 mitotic cytokinesis checkpoint(GO:0044878)
0.3 0.8 GO:0051329 interphase(GO:0051325) mitotic interphase(GO:0051329)
0.2 0.6 GO:0010845 positive regulation of reciprocal meiotic recombination(GO:0010845)
0.2 0.5 GO:1904959 elastin biosynthetic process(GO:0051542) regulation of electron carrier activity(GO:1904732) regulation of cytochrome-c oxidase activity(GO:1904959)
0.2 0.5 GO:0015881 creatine transport(GO:0015881)
0.2 1.3 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560)
0.1 0.6 GO:0010510 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510)
0.1 0.6 GO:0035063 nuclear speck organization(GO:0035063)
0.1 0.6 GO:0048165 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.1 0.5 GO:0090472 dibasic protein processing(GO:0090472)
0.1 0.4 GO:2001206 positive regulation of osteoclast development(GO:2001206)
0.1 0.3 GO:0070649 formin-nucleated actin cable assembly(GO:0070649)
0.1 0.4 GO:0018201 peptidyl-glycine modification(GO:0018201)
0.1 0.6 GO:2000234 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.1 0.4 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.1 0.2 GO:1901420 negative regulation of response to alcohol(GO:1901420)
0.1 0.3 GO:0044313 protein K6-linked deubiquitination(GO:0044313) protein K27-linked deubiquitination(GO:1990167)
0.1 2.4 GO:0010960 magnesium ion homeostasis(GO:0010960)
0.1 0.3 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.1 0.4 GO:0070535 histone H2A K63-linked ubiquitination(GO:0070535)
0.1 0.7 GO:0009162 deoxyribonucleoside monophosphate metabolic process(GO:0009162)
0.1 1.0 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.1 0.2 GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
0.1 0.2 GO:0006295 pyrimidine dimer repair by nucleotide-excision repair(GO:0000720) nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295) nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296) positive regulation of t-circle formation(GO:1904431)
0.1 0.2 GO:0035087 siRNA loading onto RISC involved in RNA interference(GO:0035087)
0.1 0.5 GO:0000492 box C/D snoRNP assembly(GO:0000492) positive regulation of plasminogen activation(GO:0010756)
0.1 1.0 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.1 0.3 GO:2001184 myoblast differentiation involved in skeletal muscle regeneration(GO:0014835) positive regulation of interleukin-12 secretion(GO:2001184)
0.1 0.3 GO:0010637 negative regulation of mitochondrial fusion(GO:0010637)
0.1 0.4 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 0.4 GO:0030035 microspike assembly(GO:0030035)
0.0 0.1 GO:0060574 intestinal epithelial cell maturation(GO:0060574)
0.0 0.1 GO:2000686 regulation of rubidium ion transmembrane transporter activity(GO:2000686)
0.0 0.8 GO:0090161 Golgi ribbon formation(GO:0090161)
0.0 0.2 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.0 0.5 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.0 0.8 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.3 GO:0030242 pexophagy(GO:0030242)
0.0 0.2 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.0 0.8 GO:0008210 estrogen metabolic process(GO:0008210)
0.0 0.3 GO:0071698 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.0 0.2 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0 0.6 GO:0070986 left/right axis specification(GO:0070986)
0.0 0.1 GO:0002023 reduction of food intake in response to dietary excess(GO:0002023)
0.0 1.4 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.2 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.0 0.2 GO:0031547 brain-derived neurotrophic factor receptor signaling pathway(GO:0031547)
0.0 0.3 GO:0035404 histone-serine phosphorylation(GO:0035404)
0.0 0.4 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.1 GO:0090168 Golgi reassembly(GO:0090168)
0.0 0.4 GO:0007191 adenylate cyclase-activating dopamine receptor signaling pathway(GO:0007191)
0.0 0.1 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.0 0.4 GO:0039702 viral budding via host ESCRT complex(GO:0039702)
0.0 0.3 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.0 0.1 GO:0036324 vascular endothelial growth factor receptor-2 signaling pathway(GO:0036324)
0.0 0.4 GO:0018195 peptidyl-arginine modification(GO:0018195)
0.0 0.1 GO:2000812 unidimensional cell growth(GO:0009826) establishment or maintenance of cell polarity regulating cell shape(GO:0071963) regulation of barbed-end actin filament capping(GO:2000812)
0.0 0.8 GO:0045725 positive regulation of glycogen biosynthetic process(GO:0045725)
0.0 0.3 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.0 0.7 GO:0000470 maturation of LSU-rRNA(GO:0000470)
0.0 1.0 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.0 0.1 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.0 0.3 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.0 0.4 GO:0045943 positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.0 0.1 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.0 0.1 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 0.4 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.0 0.2 GO:2001214 positive regulation of vasculogenesis(GO:2001214)
0.0 0.2 GO:1904869 protein localization to nuclear body(GO:1903405) protein localization to Cajal body(GO:1904867) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871) protein localization to nucleoplasm(GO:1990173)
0.0 0.1 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.0 0.1 GO:0090245 axis elongation involved in somitogenesis(GO:0090245)
0.0 0.4 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 0.4 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.0 0.1 GO:0043922 negative regulation by host of viral transcription(GO:0043922)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0005899 insulin receptor complex(GO:0005899)
0.2 0.6 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
0.2 1.3 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.2 1.8 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.1 1.7 GO:0097431 mitotic spindle pole(GO:0097431)
0.1 0.5 GO:0097255 R2TP complex(GO:0097255)
0.1 0.2 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.1 0.4 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.1 0.7 GO:0070545 PeBoW complex(GO:0070545)
0.1 0.9 GO:0090543 Flemming body(GO:0090543)
0.1 0.6 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.3 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.0 0.4 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.2 GO:0044308 axonal spine(GO:0044308)
0.0 0.5 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.1 GO:0001674 female germ cell nucleus(GO:0001674)
0.0 0.1 GO:1990597 parallel fiber(GO:1990032) AIP1-IRE1 complex(GO:1990597)
0.0 0.9 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.2 GO:0001940 male pronucleus(GO:0001940)
0.0 0.2 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.0 0.2 GO:0070578 RISC-loading complex(GO:0070578)
0.0 0.2 GO:0008290 F-actin capping protein complex(GO:0008290)
0.0 0.3 GO:0031597 proteasome regulatory particle, base subcomplex(GO:0008540) cytosolic proteasome complex(GO:0031597)
0.0 0.3 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.4 GO:0043194 axon initial segment(GO:0043194)
0.0 1.0 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)
0.0 0.2 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.7 GO:0043034 costamere(GO:0043034)
0.0 0.1 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 0.1 GO:0061574 ASAP complex(GO:0061574)
0.0 0.1 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.0 0.2 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.0 0.8 GO:0031985 Golgi cisterna(GO:0031985)
0.0 0.6 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.2 GO:0000242 pericentriolar material(GO:0000242)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.1 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.3 2.3 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.3 0.8 GO:0019150 D-ribulokinase activity(GO:0019150)
0.2 1.0 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.2 1.3 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.2 1.0 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.2 0.5 GO:0005308 creatine transmembrane transporter activity(GO:0005308)
0.1 0.6 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.1 0.5 GO:0004008 copper-exporting ATPase activity(GO:0004008) copper-transporting ATPase activity(GO:0043682)
0.1 0.7 GO:0001094 TFIID-class transcription factor binding(GO:0001094)
0.1 0.2 GO:0005275 amine transmembrane transporter activity(GO:0005275)
0.1 0.4 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1 1.4 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.6 GO:0005025 transforming growth factor beta receptor activity, type I(GO:0005025)
0.0 1.0 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.5 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 1.1 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.0 0.4 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.4 GO:0000182 rDNA binding(GO:0000182)
0.0 0.2 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.7 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.3 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.0 0.3 GO:0035174 histone serine kinase activity(GO:0035174)
0.0 0.2 GO:0004525 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.0 0.5 GO:0048406 nerve growth factor binding(GO:0048406)
0.0 0.8 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.1 GO:0004342 glucosamine-6-phosphate deaminase activity(GO:0004342)
0.0 0.3 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.2 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.0 0.4 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.0 0.5 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.0 1.4 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.6 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.2 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.2 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 0.5 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds(GO:0016799)
0.0 0.1 GO:0001716 L-amino-acid oxidase activity(GO:0001716)
0.0 0.2 GO:0035197 RNA 7-methylguanosine cap binding(GO:0000340) siRNA binding(GO:0035197)
0.0 0.2 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.1 GO:0004774 succinate-CoA ligase activity(GO:0004774)
0.0 0.3 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.1 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.0 0.8 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.4 GO:0042054 histone methyltransferase activity(GO:0042054)
0.0 0.3 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.3 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.4 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.3 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.0 0.6 GO:0005158 insulin receptor binding(GO:0005158)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.2 PID ATM PATHWAY ATM pathway
0.0 1.8 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 0.7 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.7 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.5 PID MYC PATHWAY C-MYC pathway
0.0 0.6 PID BMP PATHWAY BMP receptor signaling
0.0 0.8 PID INSULIN PATHWAY Insulin Pathway
0.0 0.5 PID IL3 PATHWAY IL3-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.8 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.1 0.8 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.6 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.0 1.2 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.5 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.0 0.3 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.3 REACTOME DSCAM INTERACTIONS Genes involved in DSCAM interactions
0.0 0.5 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.6 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 0.6 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.8 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.5 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.0 0.6 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0 0.2 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 0.2 REACTOME GLOBAL GENOMIC NER GG NER Genes involved in Global Genomic NER (GG-NER)