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2D miR_HR1_12

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Results for Zfhx3

Z-value: 0.36

Motif logo

Transcription factors associated with Zfhx3

Gene Symbol Gene ID Gene Info
ENSMUSG00000038872.8 zinc finger homeobox 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Zfhx3mm10_v2_chr8_+_108714644_1087146440.088.1e-01Click!

Activity profile of Zfhx3 motif

Sorted Z-values of Zfhx3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr7_+_30493622 0.57 ENSMUST00000058280.6
ENSMUST00000133318.1
ENSMUST00000142575.1
ENSMUST00000131040.1
proline dehydrogenase (oxidase) 2
chrX_-_162964557 0.55 ENSMUST00000038769.2
S100 calcium binding protein G
chr15_-_79285470 0.51 ENSMUST00000170955.1
BAI1-associated protein 2-like 2
chr15_-_79285502 0.46 ENSMUST00000165408.1
BAI1-associated protein 2-like 2
chr9_+_55326913 0.32 ENSMUST00000085754.3
ENSMUST00000034862.4
expressed sequence AI118078
chr2_-_121235689 0.29 ENSMUST00000142400.1
transformation related protein 53 binding protein 1
chr9_+_53771499 0.26 ENSMUST00000048670.8
solute carrier family 35, member F2
chr15_-_55548164 0.23 ENSMUST00000165356.1
mitochondrial ribosomal protein L13
chr1_-_12991109 0.22 ENSMUST00000115403.2
ENSMUST00000115402.1
solute carrier organic anion transporter family, member 5A1
chr18_+_11633276 0.20 ENSMUST00000115861.2
retinoblastoma binding protein 8
chr3_-_72967854 0.19 ENSMUST00000167334.1
sucrase isomaltase (alpha-glucosidase)
chr3_-_145032765 0.18 ENSMUST00000029919.5
chloride channel calcium activated 3
chr17_-_43502773 0.18 ENSMUST00000024707.8
ENSMUST00000117137.1
meprin 1 alpha
chr2_-_140671462 0.18 ENSMUST00000110057.2
fibronectin leucine rich transmembrane protein 3
chr2_+_121506748 0.17 ENSMUST00000099473.3
ENSMUST00000110602.2
WD repeat domain 76
chr9_+_95857597 0.16 ENSMUST00000034980.7
ataxia telangiectasia and Rad3 related
chr4_-_32923455 0.16 ENSMUST00000035719.4
ENSMUST00000084749.1
ankyrin repeat domain 6
chr13_-_58354862 0.14 ENSMUST00000043605.5
kinesin family member 27
chrX_-_111536325 0.14 ENSMUST00000156639.1
ribosomal protein S6 kinase polypeptide 6
chr9_+_36832684 0.14 ENSMUST00000034630.8
fasciculation and elongation protein zeta 1 (zygin I)
chr12_+_71170589 0.13 ENSMUST00000129376.1
RIKEN cDNA 2700049A03 gene
chr17_-_40880525 0.13 ENSMUST00000068258.2
RIKEN cDNA 9130008F23 gene
chr3_-_130730375 0.12 ENSMUST00000079085.6
ribosomal protein L34
chrM_-_14060 0.12 ENSMUST00000082419.1
mitochondrially encoded NADH dehydrogenase 6
chr8_-_66486494 0.12 ENSMUST00000026681.5
translation machinery associated 16 homolog (S. cerevisiae)
chr2_-_140671400 0.12 ENSMUST00000056760.3
fibronectin leucine rich transmembrane protein 3
chr13_-_110280103 0.12 ENSMUST00000167824.1
RAB3C, member RAS oncogene family
chr11_+_24078173 0.11 ENSMUST00000109514.1
B cell CLL/lymphoma 11A (zinc finger protein)
chr19_+_30232921 0.11 ENSMUST00000025797.5
mannose-binding lectin (protein C) 2
chr3_+_138217814 0.11 ENSMUST00000090171.5
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chrM_+_7759 0.11 ENSMUST00000082407.1
ENSMUST00000082408.1
mitochondrially encoded ATP synthase 8
mitochondrially encoded ATP synthase 6
chr1_+_172698046 0.11 ENSMUST00000038495.3
C-reactive protein, pentraxin-related
chr3_-_138131356 0.10 ENSMUST00000029805.8
microsomal triglyceride transfer protein
chr7_-_101837776 0.10 ENSMUST00000165052.1
inositol polyphosphate phosphatase-like 1
chr18_+_56562443 0.10 ENSMUST00000130163.1
ENSMUST00000132628.1
phosphorylated adaptor for RNA export
chrM_+_9452 0.09 ENSMUST00000082411.1
mitochondrially encoded NADH dehydrogenase 3
chrX_-_143933089 0.09 ENSMUST00000087313.3
doublecortin
chr3_+_136670076 0.09 ENSMUST00000070198.7
protein phosphatase 3, catalytic subunit, alpha isoform
chr9_-_118014160 0.09 ENSMUST00000111769.3
zinc finger, CW type with PWWP domain 2
chr11_+_24078022 0.09 ENSMUST00000000881.6
B cell CLL/lymphoma 11A (zinc finger protein)
chr3_+_76075583 0.09 ENSMUST00000160261.1
follistatin-like 5
chr4_+_109343029 0.08 ENSMUST00000030281.5
epidermal growth factor receptor pathway substrate 15
chrM_+_14138 0.08 ENSMUST00000082421.1
mitochondrially encoded cytochrome b
chr14_+_64588112 0.08 ENSMUST00000181808.1
RIKEN cDNA A930011O12 gene
chr9_+_75051977 0.08 ENSMUST00000170310.1
ENSMUST00000166549.1
cAMP-regulated phosphoprotein 19
chr4_+_13743424 0.08 ENSMUST00000006761.3
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr11_+_101367542 0.08 ENSMUST00000019469.2
glucose-6-phosphatase, catalytic
chrM_+_2743 0.08 ENSMUST00000082392.1
mitochondrially encoded NADH dehydrogenase 1
chr8_-_67818218 0.07 ENSMUST00000059374.4
pleckstrin and Sec7 domain containing 3
chr13_-_75943812 0.07 ENSMUST00000022078.5
ENSMUST00000109606.1
Rho-related BTB domain containing 3
chrX_+_107255878 0.07 ENSMUST00000101294.2
ENSMUST00000118820.1
ENSMUST00000120971.1
G protein-coupled receptor 174
chr10_+_23797052 0.07 ENSMUST00000133289.1
solute carrier family 18, subfamily B, member 1
chr6_-_38124568 0.07 ENSMUST00000040259.4
ATPase, H+ transporting, lysosomal V0 subunit A4
chrM_+_7005 0.06 ENSMUST00000082405.1
mitochondrially encoded cytochrome c oxidase II
chr3_+_84952146 0.06 ENSMUST00000029727.7
F-box and WD-40 domain protein 7
chr11_+_24078111 0.06 ENSMUST00000109516.1
B cell CLL/lymphoma 11A (zinc finger protein)
chr8_+_93810832 0.06 ENSMUST00000034198.8
ENSMUST00000125716.1
guanine nucleotide binding protein, alpha O
chrM_+_9870 0.06 ENSMUST00000084013.1
mitochondrially encoded NADH dehydrogenase 4L
chr4_+_115884384 0.06 ENSMUST00000097918.2
kinocilin
chr1_-_24612700 0.06 ENSMUST00000088336.1
predicted gene 10222
chr18_+_32815383 0.06 ENSMUST00000025237.3
thymic stromal lymphopoietin
chr3_+_108940108 0.06 ENSMUST00000098680.2
HEN1 methyltransferase homolog 1 (Arabidopsis)
chr10_-_17947997 0.06 ENSMUST00000037879.6
headcase homolog (Drosophila)
chr5_+_35041539 0.05 ENSMUST00000030985.6
hepatocyte growth factor activator
chr6_-_129100903 0.05 ENSMUST00000032258.6
C-type lectin domain family 2, member e
chr9_-_70934808 0.05 ENSMUST00000034731.8
lipase, hepatic
chr8_+_47713266 0.05 ENSMUST00000180928.1
RIKEN cDNA E030037K01 gene
chr1_-_126830786 0.05 ENSMUST00000162646.1
NCK-associated protein 5
chrX_-_143933204 0.05 ENSMUST00000112851.1
ENSMUST00000112856.2
ENSMUST00000033642.3
doublecortin
chr6_-_86765807 0.05 ENSMUST00000123732.1
annexin A4
chr4_+_101507947 0.05 ENSMUST00000149047.1
ENSMUST00000106929.3
DnaJ (Hsp40) homolog, subfamily C, member 6
chr1_-_138175238 0.05 ENSMUST00000182536.1
protein tyrosine phosphatase, receptor type, C
chrX_-_139871637 0.04 ENSMUST00000033811.7
ENSMUST00000087401.5
microrchidia 4
chr6_-_86765866 0.04 ENSMUST00000113675.1
annexin A4
chr16_-_79091078 0.04 ENSMUST00000023566.4
ENSMUST00000060402.5
transmembrane protease, serine 15
chr2_-_37647199 0.04 ENSMUST00000028279.3
spermatid perinuclear RNA binding protein
chr9_+_54980880 0.04 ENSMUST00000093844.3
cholinergic receptor, nicotinic, alpha polypeptide 5
chr1_-_138175126 0.04 ENSMUST00000183301.1
protein tyrosine phosphatase, receptor type, C
chr2_-_140671440 0.04 ENSMUST00000099301.1
fibronectin leucine rich transmembrane protein 3
chrM_+_8600 0.03 ENSMUST00000082409.1
mitochondrially encoded cytochrome c oxidase III
chr11_-_79530569 0.03 ENSMUST00000103236.3
ENSMUST00000170799.1
ENSMUST00000170422.2
ecotropic viral integration site 2a
ecotropic viral integration site 2b
chr1_+_174172738 0.03 ENSMUST00000027817.7
spectrin alpha, erythrocytic 1
chr8_+_83666827 0.03 ENSMUST00000019608.5
prostaglandin E receptor 1 (subtype EP1)
chr17_+_12378603 0.03 ENSMUST00000014578.5
plasminogen
chr7_-_100583072 0.03 ENSMUST00000152876.1
ENSMUST00000150042.1
mitochondrial ribosomal protein L48
chr13_-_23914998 0.03 ENSMUST00000021769.8
ENSMUST00000110407.2
solute carrier family 17 (sodium phosphate), member 4
chr19_-_31765027 0.03 ENSMUST00000065067.6
protein kinase, cGMP-dependent, type I
chr9_+_7571396 0.03 ENSMUST00000120900.1
ENSMUST00000093896.3
ENSMUST00000151853.1
ENSMUST00000152878.1
matrix metallopeptidase 27
chr12_-_87443800 0.03 ENSMUST00000162961.1
alkB, alkylation repair homolog 1 (E. coli)
chr15_+_91231578 0.03 ENSMUST00000109284.2
cDNA sequence CN725425
chrX_+_112311334 0.02 ENSMUST00000026599.3
ENSMUST00000113415.1
apolipoprotein O-like
chr19_+_48206025 0.02 ENSMUST00000078880.5
sortilin-related VPS10 domain containing receptor 3
chr10_-_88605017 0.02 ENSMUST00000119185.1
ENSMUST00000121629.1
myosin binding protein C, slow-type
chr1_+_58113136 0.02 ENSMUST00000040999.7
aldehyde oxidase 3
chr1_-_138175283 0.02 ENSMUST00000182755.1
ENSMUST00000183262.1
ENSMUST00000027645.7
ENSMUST00000112036.2
ENSMUST00000182283.1
protein tyrosine phosphatase, receptor type, C
chr2_+_162987502 0.01 ENSMUST00000117123.1
serum/glucocorticoid regulated kinase 2
chr2_+_3770673 0.01 ENSMUST00000177037.1
family with sequence similarity 107, member B
chr18_+_73863672 0.01 ENSMUST00000134847.1
maestro
chr19_-_46672883 0.01 ENSMUST00000026012.7
cytochrome P450, family 17, subfamily a, polypeptide 1
chr3_+_108571699 0.01 ENSMUST00000143054.1
TAF13 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr7_-_99980431 0.01 ENSMUST00000080817.4
ring finger protein 169
chr17_+_36958623 0.01 ENSMUST00000173814.1
Znrd1 antisense
chr1_+_74661794 0.01 ENSMUST00000129890.1
tubulin tyrosine ligase-like family, member 4
chr17_+_36958571 0.01 ENSMUST00000040177.6
Znrd1 antisense
chr17_+_35076902 0.01 ENSMUST00000172494.1
ENSMUST00000172678.1
ENSMUST00000013910.4
lymphocyte antigen 6 complex, locus G6E
chr3_+_66985647 0.01 ENSMUST00000162362.1
ENSMUST00000065074.7
arginine/serine-rich coiled-coil 1
chr2_-_63184253 0.01 ENSMUST00000075052.3
ENSMUST00000112454.1
potassium voltage-gated channel, subfamily H (eag-related), member 7
chr3_+_66985680 0.01 ENSMUST00000065047.6
arginine/serine-rich coiled-coil 1
chr13_+_23839401 0.01 ENSMUST00000039721.7
ENSMUST00000166467.1
solute carrier family 17 (sodium phosphate), member 3
chr13_+_23839445 0.00 ENSMUST00000091698.4
ENSMUST00000110422.1
solute carrier family 17 (sodium phosphate), member 3
chr1_-_168432270 0.00 ENSMUST00000072863.4
pre B cell leukemia homeobox 1
chr5_+_24394388 0.00 ENSMUST00000115074.1
ATP-binding cassette, sub-family B (MDR/TAP), member 8
chr1_-_172895048 0.00 ENSMUST00000027824.5
serum amyloid P-component
chr17_-_50094277 0.00 ENSMUST00000113195.1
raftlin lipid raft linker 1
chr2_-_165368723 0.00 ENSMUST00000141140.1
ENSMUST00000103085.1
zinc finger protein 663
chr3_+_153844209 0.00 ENSMUST00000044089.3
ankyrin repeat and SOCS box-containing 17

Network of associatons between targets according to the STRING database.

First level regulatory network of Zfhx3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.1 0.3 GO:0003345 proepicardium cell migration involved in pericardium morphogenesis(GO:0003345)
0.1 0.3 GO:1904800 regulation of neuron remodeling(GO:1904799) negative regulation of neuron remodeling(GO:1904800)
0.1 0.2 GO:1904882 telomerase catalytic core complex assembly(GO:1904868) regulation of telomerase catalytic core complex assembly(GO:1904882) positive regulation of telomerase catalytic core complex assembly(GO:1904884)
0.0 1.0 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.0 0.2 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.0 0.1 GO:0051030 snRNA transport(GO:0051030)
0.0 0.1 GO:1903244 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244)
0.0 0.1 GO:0006069 ethanol oxidation(GO:0006069)
0.0 0.1 GO:0034196 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.0 0.1 GO:0002378 immunoglobulin biosynthetic process(GO:0002378) regulation of hematopoietic stem cell migration(GO:2000471) positive regulation of hematopoietic stem cell migration(GO:2000473)
0.0 0.3 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.0 0.1 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.0 0.1 GO:0033762 response to glucagon(GO:0033762)
0.0 0.1 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.0 0.1 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 0.1 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.0 0.1 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.0 0.1 GO:2000483 negative regulation of interleukin-8 secretion(GO:2000483)
0.0 0.1 GO:0043569 negative regulation of insulin-like growth factor receptor signaling pathway(GO:0043569)
0.0 0.1 GO:2000381 negative regulation of mesoderm development(GO:2000381)
0.0 0.1 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 GO:0071439 clathrin complex(GO:0071439)
0.0 0.1 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 0.1 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.1 GO:0032437 cuticular plate(GO:0032437)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0005499 vitamin D binding(GO:0005499)
0.0 0.3 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.0 0.2 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.0 0.1 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.0 0.2 GO:0032405 MutLalpha complex binding(GO:0032405) MutSalpha complex binding(GO:0032407)
0.0 0.1 GO:0050309 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.0 0.3 GO:0045499 chemorepellent activity(GO:0045499)
0.0 0.6 GO:0071949 FAD binding(GO:0071949)
0.0 0.1 GO:0005534 galactose binding(GO:0005534)
0.0 0.1 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.2 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0 0.1 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.1 GO:0050816 phosphothreonine binding(GO:0050816)
0.0 0.4 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.1 GO:0016681 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.1 GO:0051430 corticotropin-releasing hormone receptor 1 binding(GO:0051430)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.1 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.2 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint