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2D miR_HR1_12

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Results for Tbx1_Eomes

Z-value: 0.58

Motif logo

Transcription factors associated with Tbx1_Eomes

Gene Symbol Gene ID Gene Info
ENSMUSG00000009097.9 T-box 1
ENSMUSG00000032446.8 eomesodermin

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Eomesmm10_v2_chr9_+_118478344_118478451-0.661.9e-02Click!
Tbx1mm10_v2_chr16_-_18586959_185869700.293.5e-01Click!

Activity profile of Tbx1_Eomes motif

Sorted Z-values of Tbx1_Eomes motif

Promoter Log-likelihood Transcript Gene Gene Info
chr19_+_37436707 1.61 ENSMUST00000128184.1
hematopoietically expressed homeobox
chr7_+_79810727 1.38 ENSMUST00000107394.1
mesoderm posterior 2
chr8_-_105933832 1.28 ENSMUST00000034368.6
chymotrypsin-like
chr7_-_4546567 1.17 ENSMUST00000065957.5
synaptotagmin V
chr7_-_100658394 1.13 ENSMUST00000138830.1
ENSMUST00000107044.3
ENSMUST00000116287.2
pleckstrin homology domain containing, family B (evectins) member 1
chrX_+_101383726 1.11 ENSMUST00000119190.1
gap junction protein, beta 1
chr7_-_79793788 0.93 ENSMUST00000032760.5
mesoderm posterior 1
chr7_-_100658364 0.89 ENSMUST00000107043.1
pleckstrin homology domain containing, family B (evectins) member 1
chr11_+_120530688 0.80 ENSMUST00000026119.7
glucagon receptor
chr16_-_32797413 0.71 ENSMUST00000115116.1
ENSMUST00000041123.8
mucin 20
chr1_+_164115264 0.67 ENSMUST00000162746.1
selectin, platelet
chr6_-_116716888 0.65 ENSMUST00000056623.6
transmembrane protein 72
chr2_+_54436317 0.63 ENSMUST00000112636.1
ENSMUST00000112635.1
ENSMUST00000112634.1
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 13
chrX_+_159840463 0.58 ENSMUST00000112451.1
ENSMUST00000112453.2
SH3-domain kinase binding protein 1
chr2_+_164562579 0.52 ENSMUST00000017867.3
ENSMUST00000109344.2
ENSMUST00000109345.2
WAP four-disulfide core domain 2
chr4_+_43641262 0.51 ENSMUST00000123351.1
ENSMUST00000128549.1
natriuretic peptide receptor 2
chr11_-_94507337 0.51 ENSMUST00000040692.8
MYCBP associated protein
chr11_+_98348404 0.48 ENSMUST00000078694.6
protein phosphatase 1, regulatory (inhibitor) subunit 1B
chr10_+_115817247 0.48 ENSMUST00000035563.7
ENSMUST00000080630.3
ENSMUST00000179196.1
tetraspanin 8
chr4_-_42168603 0.48 ENSMUST00000098121.3
predicted gene 13305
chr4_+_84884366 0.46 ENSMUST00000102819.3
centlein, centrosomal protein
chr6_+_7555053 0.45 ENSMUST00000090679.2
ENSMUST00000184986.1
tachykinin 1
chr6_-_122609964 0.43 ENSMUST00000032211.4
growth differentiation factor 3
chr4_+_84884418 0.42 ENSMUST00000169371.2
centlein, centrosomal protein
chr7_+_25306085 0.42 ENSMUST00000119703.1
ENSMUST00000108409.1
transmembrane protein 145
chr17_-_31144271 0.39 ENSMUST00000024826.7
trefoil factor 2 (spasmolytic protein 1)
chr14_-_30943275 0.39 ENSMUST00000006704.8
ENSMUST00000163118.1
inter-alpha trypsin inhibitor, heavy chain 1
chr4_+_84884276 0.37 ENSMUST00000047023.6
centlein, centrosomal protein
chr16_+_87553313 0.37 ENSMUST00000026700.7
Map3k7 C-terminal like
chrX_+_41401304 0.36 ENSMUST00000076349.5
glutamate receptor, ionotropic, AMPA3 (alpha 3)
chr11_+_121237216 0.36 ENSMUST00000103015.3
nuclear prelamin A recognition factor
chr15_+_57694651 0.36 ENSMUST00000096430.4
zinc fingers and homeoboxes 2
chr11_-_84068357 0.35 ENSMUST00000100705.4
dual specificity phosphatase 14
chr4_+_41760454 0.34 ENSMUST00000108040.1
interleukin 11 receptor, alpha chain 1
chr11_+_53519725 0.34 ENSMUST00000108987.1
ENSMUST00000121334.1
ENSMUST00000117061.1
septin 8
chr1_-_174921813 0.31 ENSMUST00000055294.3
gremlin 2 homolog, cysteine knot superfamily (Xenopus laevis)
chr10_-_24101951 0.30 ENSMUST00000170267.1
trace amine-associated receptor 8C
chr13_-_113180897 0.30 ENSMUST00000038212.7
granzyme K
chrX_+_41401128 0.30 ENSMUST00000115103.2
glutamate receptor, ionotropic, AMPA3 (alpha 3)
chr11_+_103101682 0.30 ENSMUST00000107040.3
ENSMUST00000140372.1
ENSMUST00000024492.8
ENSMUST00000134884.1
acyl-Coenzyme A binding domain containing 4
chr9_+_35211155 0.29 ENSMUST00000034541.5
signal recognition particle receptor ('docking protein')
chr9_-_41004562 0.29 ENSMUST00000034519.6
cytotoxic and regulatory T cell molecule
chrX_+_41401476 0.29 ENSMUST00000165288.1
glutamate receptor, ionotropic, AMPA3 (alpha 3)
chr11_-_84068766 0.28 ENSMUST00000018792.5
dual specificity phosphatase 14
chr9_+_37208291 0.28 ENSMUST00000034632.8
transmembrane protein 218
chr11_-_51857624 0.28 ENSMUST00000020655.7
ENSMUST00000109090.1
PHD finger protein 15
chr19_+_53460610 0.27 ENSMUST00000180442.1
RIKEN cDNA 4833407H14 gene
chr11_-_117969176 0.27 ENSMUST00000054002.3
suppressor of cytokine signaling 3
chr8_+_45885479 0.26 ENSMUST00000034053.5
PDZ and LIM domain 3
chr1_+_180935022 0.25 ENSMUST00000037361.8
left right determination factor 1
chr4_+_125490688 0.25 ENSMUST00000030676.7
glutamate receptor, ionotropic, kainate 3
chrX_+_142681398 0.25 ENSMUST00000112889.1
ENSMUST00000101198.2
ENSMUST00000112891.1
ENSMUST00000087333.2
transmembrane protein 164
chr2_+_172979827 0.24 ENSMUST00000109125.1
ENSMUST00000050442.9
ENSMUST00000109126.3
SPO11 meiotic protein covalently bound to DSB homolog (S. cerevisiae)
chr9_-_41004599 0.23 ENSMUST00000180384.1
cytotoxic and regulatory T cell molecule
chr5_-_24601961 0.23 ENSMUST00000030791.7
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3
chr19_+_20601958 0.22 ENSMUST00000087638.3
aldehyde dehydrogenase family 1, subfamily A1
chrX_+_163908982 0.22 ENSMUST00000069041.8
adaptor-related protein complex 1, sigma 2 subunit
chr14_-_51988829 0.19 ENSMUST00000181008.1
predicted gene, 16617
chr9_+_15239045 0.19 ENSMUST00000034413.6
V-set and transmembrane domain containing 5
chr8_-_8639363 0.19 ENSMUST00000152698.1
ephrin B2
chr2_+_160880642 0.18 ENSMUST00000109456.2
lipin 3
chr4_-_99654983 0.18 ENSMUST00000136525.1
predicted gene 12688
chr4_-_35845204 0.18 ENSMUST00000164772.1
ENSMUST00000065173.2
leucine rich repeat and Ig domain containing 2
chr19_+_4097392 0.18 ENSMUST00000174514.1
ENSMUST00000174149.1
CDK2-associated protein 2
chr2_+_32609043 0.18 ENSMUST00000128811.1
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
chr19_-_28963863 0.18 ENSMUST00000161813.1
RIKEN cDNA 4430402I18 gene
chr9_+_75311395 0.17 ENSMUST00000076889.6
guanine nucleotide binding protein (G protein), beta 5
chr14_-_70177668 0.17 ENSMUST00000022681.4
PDZ and LIM domain 2
chr5_-_24329556 0.17 ENSMUST00000115098.2
potassium voltage-gated channel, subfamily H (eag-related), member 2
chr14_-_54712139 0.17 ENSMUST00000064290.6
CCAAT/enhancer binding protein (C/EBP), epsilon
chr10_+_116177217 0.16 ENSMUST00000148731.1
protein tyrosine phosphatase, receptor type, R
chr3_-_30140407 0.16 ENSMUST00000108271.3
MDS1 and EVI1 complex locus
chrX_+_133908418 0.16 ENSMUST00000033606.8
ENSMUST00000113303.1
ENSMUST00000165805.1
sushi-repeat-containing protein, X-linked 2
chr10_+_99263224 0.16 ENSMUST00000020118.4
dual specificity phosphatase 6
chr8_-_84147858 0.16 ENSMUST00000117424.2
ENSMUST00000040383.8
coiled-coil and C2 domain containing 1A
chr2_-_148046896 0.16 ENSMUST00000172928.1
ENSMUST00000047315.3
forkhead box A2
chr11_+_62847111 0.15 ENSMUST00000150989.1
ENSMUST00000176577.1
F-box and WD-40 domain protein 10
chr15_-_11905609 0.15 ENSMUST00000066529.3
natriuretic peptide receptor 3
chr2_+_27079371 0.15 ENSMUST00000091233.6
ADAMTS-like 2
chr4_-_133339283 0.15 ENSMUST00000043305.7
WD and tetratricopeptide repeats 1
chr1_-_126830632 0.15 ENSMUST00000112583.1
ENSMUST00000094609.3
NCK-associated protein 5
chr6_-_21851914 0.14 ENSMUST00000134635.1
ENSMUST00000123116.1
ENSMUST00000120965.1
tetraspanin 12
chr10_+_116177351 0.14 ENSMUST00000155606.1
ENSMUST00000128399.1
protein tyrosine phosphatase, receptor type, R
chr12_-_86892540 0.14 ENSMUST00000181290.1
predicted gene, 26698
chr15_-_98831498 0.14 ENSMUST00000168846.1
protein kinase, AMP-activated, gamma 1 non-catalytic subunit
chr6_-_94700137 0.14 ENSMUST00000101126.2
ENSMUST00000032105.4
leucine-rich repeats and immunoglobulin-like domains 1
chr4_+_42950369 0.14 ENSMUST00000084662.5
DnaJ (Hsp40) homolog, subfamily B, member 5
chr4_-_133339238 0.13 ENSMUST00000105906.1
WD and tetratricopeptide repeats 1
chr7_-_30563184 0.13 ENSMUST00000043898.6
presenilin enhancer 2 homolog (C. elegans)
chr2_+_25272475 0.13 ENSMUST00000028341.4
anaphase promoting complex subunit 2
chrX_-_59568068 0.13 ENSMUST00000119833.1
ENSMUST00000131319.1
fibroblast growth factor 13
chr8_+_105636509 0.13 ENSMUST00000005841.9
CCCTC-binding factor
chr3_-_94582716 0.13 ENSMUST00000029783.9
sorting nexin family member 27
chr17_-_29237759 0.13 ENSMUST00000137727.1
ENSMUST00000024805.7
copine V
chrX_+_163909132 0.13 ENSMUST00000033734.7
ENSMUST00000112294.2
adaptor-related protein complex 1, sigma 2 subunit
chr6_-_145865483 0.12 ENSMUST00000032386.4
basic helix-loop-helix family, member e41
chr16_-_95459245 0.12 ENSMUST00000176345.1
ENSMUST00000121809.2
ENSMUST00000118113.1
ENSMUST00000122199.1
avian erythroblastosis virus E-26 (v-ets) oncogene related
chr13_+_96542727 0.12 ENSMUST00000077672.4
ENSMUST00000109444.2
collagen, type IV, alpha 3 (Goodpasture antigen) binding protein
chr11_+_62847062 0.12 ENSMUST00000036085.4
F-box and WD-40 domain protein 10
chr1_-_69108039 0.12 ENSMUST00000121473.1
v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)
chr18_+_76241580 0.11 ENSMUST00000168423.1
ENSMUST00000091831.6
SMAD family member 2
chr18_-_46212595 0.11 ENSMUST00000037011.4
tripartite motif-containing 36
chr3_+_40950631 0.11 ENSMUST00000048490.6
La ribonucleoprotein domain family, member 1B
chrX_+_7919816 0.11 ENSMUST00000041096.3
proprotein convertase subtilisin/kexin type 1 inhibitor
chr11_+_98741805 0.11 ENSMUST00000064187.5
thyroid hormone receptor alpha
chr1_-_136960427 0.11 ENSMUST00000027649.7
nuclear receptor subfamily 5, group A, member 2
chr4_+_117849361 0.11 ENSMUST00000163288.1
solute carrier family 6 (neurotransmitter transporter, glycine), member 9
chr5_-_137786681 0.11 ENSMUST00000132726.1
methylphosphate capping enzyme
chrX_-_59567348 0.10 ENSMUST00000124402.1
fibroblast growth factor 13
chr10_+_86705811 0.10 ENSMUST00000061458.7
ENSMUST00000075632.6
cDNA sequence BC030307
chr9_-_43239816 0.10 ENSMUST00000034512.5
OAF homolog (Drosophila)
chr10_+_80930071 0.10 ENSMUST00000015456.8
growth arrest and DNA-damage-inducible 45 beta
chr16_+_56477838 0.10 ENSMUST00000048471.7
ENSMUST00000096013.3
ENSMUST00000096012.3
ENSMUST00000171000.1
ABI gene family, member 3 (NESH) binding protein
chr19_+_21272276 0.10 ENSMUST00000025659.4
zinc finger, AN1-type domain 5
chr10_+_26229707 0.10 ENSMUST00000060716.5
ENSMUST00000164660.1
sterile alpha motif domain containing 3
chr4_+_48045144 0.10 ENSMUST00000030025.3
nuclear receptor subfamily 4, group A, member 3
chr6_+_39573894 0.09 ENSMUST00000051249.6
aarF domain containing kinase 2
chr6_-_83527452 0.09 ENSMUST00000141904.1
actin, gamma 2, smooth muscle, enteric
chr6_-_140041409 0.09 ENSMUST00000032356.6
phospholipase C, zeta 1
chr14_+_15437623 0.09 ENSMUST00000181388.1
RIKEN cDNA B230110C06 gene
chr15_+_10952332 0.09 ENSMUST00000022853.8
ENSMUST00000110523.1
C1q and tumor necrosis factor related protein 3
chr8_+_113643206 0.08 ENSMUST00000034219.4
ENSMUST00000095173.1
synaptonemal complex central element protein 1 like
chr7_-_120095177 0.08 ENSMUST00000046993.3
dynein, axonemal, heavy chain 3
chr17_+_48932368 0.08 ENSMUST00000046254.2
leucine rich repeat and fibronectin type III domain containing 2
chr19_-_36057340 0.08 ENSMUST00000164639.1
ENSMUST00000166074.1
ENSMUST00000099505.3
5-hydroxytryptamine (serotonin) receptor 7
chr8_+_47824459 0.08 ENSMUST00000038693.6
claudin 22
chr3_+_55461758 0.08 ENSMUST00000070418.4
doublecortin-like kinase 1
chr19_+_55894508 0.08 ENSMUST00000142291.1
transcription factor 7 like 2, T cell specific, HMG box
chr13_+_113209659 0.08 ENSMUST00000038144.8
endothelial cell-specific molecule 1
chr3_+_75557530 0.08 ENSMUST00000161776.1
ENSMUST00000029423.8
serine (or cysteine) peptidase inhibitor, clade I, member 1
chr19_-_37207293 0.08 ENSMUST00000132580.1
ENSMUST00000079754.4
ENSMUST00000136286.1
ENSMUST00000126188.1
ENSMUST00000126781.1
cytoplasmic polyadenylation element binding protein 3
chrX_-_101419788 0.08 ENSMUST00000117901.1
ENSMUST00000120201.1
ENSMUST00000117637.1
ENSMUST00000134005.1
ENSMUST00000121520.1
zinc finger, MYM-type 3
chrX_+_56454871 0.07 ENSMUST00000039374.2
ENSMUST00000101553.2
DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B
chr6_+_39573858 0.07 ENSMUST00000140364.1
aarF domain containing kinase 2
chr6_-_83527773 0.07 ENSMUST00000152029.1
actin, gamma 2, smooth muscle, enteric
chr11_+_83302817 0.07 ENSMUST00000142680.1
adaptor-related protein complex 2, beta 1 subunit
chr9_-_35210964 0.07 ENSMUST00000043805.8
ENSMUST00000142595.1
ENSMUST00000127996.1
FAD-dependent oxidoreductase domain containing 1
chr2_+_163820832 0.06 ENSMUST00000029188.7
WNT1 inducible signaling pathway protein 2
chr7_+_25267669 0.06 ENSMUST00000169266.1
capicua homolog (Drosophila)
chr2_+_54436432 0.06 ENSMUST00000136642.1
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 13
chr1_+_131970589 0.06 ENSMUST00000027695.6
solute carrier family 45, member 3
chr1_+_153665666 0.06 ENSMUST00000111814.1
ENSMUST00000111810.1
regulator of G-protein signaling 8
chr5_-_137786651 0.06 ENSMUST00000031740.9
methylphosphate capping enzyme
chr5_+_120513102 0.06 ENSMUST00000111889.1
solute carrier family 8 (sodium/lithium/calcium exchanger), member B1
chr4_-_82505749 0.06 ENSMUST00000107245.2
ENSMUST00000107246.1
nuclear factor I/B
chr16_-_23988852 0.06 ENSMUST00000023151.5
B cell leukemia/lymphoma 6
chr1_+_180726019 0.06 ENSMUST00000027780.4
acyl-Coenzyme A binding domain containing 3
chr15_+_74516196 0.05 ENSMUST00000042035.9
brain-specific angiogenesis inhibitor 1
chr2_+_20519776 0.05 ENSMUST00000114604.2
ENSMUST00000066509.3
enhancer trap locus 4
chr11_+_96323253 0.05 ENSMUST00000093944.3
homeobox B3
chr13_+_96542602 0.05 ENSMUST00000179226.1
collagen, type IV, alpha 3 (Goodpasture antigen) binding protein
chr16_-_32868325 0.05 ENSMUST00000089684.3
ENSMUST00000040986.8
ENSMUST00000115105.2
RIKEN cDNA 1700021K19 gene
chr4_-_123750236 0.05 ENSMUST00000102636.3
akirin 1
chr10_+_56377300 0.05 ENSMUST00000068581.7
gap junction protein, alpha 1
chr1_-_161876656 0.05 ENSMUST00000048377.5
SUN domain containing ossification factor
chr18_+_34840575 0.04 ENSMUST00000043484.7
receptor accessory protein 2
chr11_-_86683761 0.04 ENSMUST00000018315.3
vacuole membrane protein 1
chr18_+_60963517 0.04 ENSMUST00000115295.2
ENSMUST00000039904.6
calcium/calmodulin-dependent protein kinase II alpha
chr1_+_171329015 0.04 ENSMUST00000111300.1
death effector domain-containing
chr9_-_21073494 0.04 ENSMUST00000010348.5
ferredoxin 1-like
chr10_-_128211788 0.04 ENSMUST00000061995.8
SPRY domain containing 4
chr11_-_103101609 0.03 ENSMUST00000103077.1
phospholipase C, delta 3
chr17_+_35135695 0.03 ENSMUST00000174478.1
ENSMUST00000174281.2
ENSMUST00000173550.1
BCL2-associated athanogene 6
chr1_-_134332928 0.03 ENSMUST00000168515.1
protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4
chr1_+_153665274 0.03 ENSMUST00000152114.1
ENSMUST00000111812.1
regulator of G-protein signaling 8
chr6_+_83054653 0.03 ENSMUST00000092618.6
ancient ubiquitous protein 1
chr7_-_115824699 0.03 ENSMUST00000169129.1
SRY-box containing gene 6
chr6_-_52165413 0.03 ENSMUST00000014848.8
homeobox A2
chr9_-_49798729 0.03 ENSMUST00000166811.2
neural cell adhesion molecule 1
chr5_+_31094984 0.03 ENSMUST00000066505.1
predicted gene 9924
chr18_+_65582390 0.03 ENSMUST00000169679.1
ENSMUST00000183326.1
zinc finger protein 532
chr3_-_10208569 0.03 ENSMUST00000029041.4
fatty acid binding protein 4, adipocyte
chr6_-_92214897 0.02 ENSMUST00000014694.8
zinc finger, FYVE domain containing 20
chr1_+_180893107 0.02 ENSMUST00000085797.5
left-right determination factor 2
chr2_-_13011747 0.02 ENSMUST00000061545.5
C1q-like 3
chr7_-_114117761 0.01 ENSMUST00000069449.5
related RAS viral (r-ras) oncogene homolog 2
chr6_+_72304592 0.01 ENSMUST00000183018.1
surfactant associated protein B
chr12_+_88953399 0.01 ENSMUST00000057634.7
neurexin III
chr7_-_81566939 0.01 ENSMUST00000042318.5
fibronectin type III and SPRY domain containing 2
chr18_-_65393844 0.01 ENSMUST00000035548.8
alpha-kinase 2
chr10_-_86705485 0.01 ENSMUST00000020238.7
heat shock protein 90, beta (Grp94), member 1
chr1_-_56971762 0.01 ENSMUST00000114415.3
special AT-rich sequence binding protein 2
chr2_-_148045891 0.01 ENSMUST00000109964.1
forkhead box A2
chr7_+_30291659 0.01 ENSMUST00000014065.8
ENSMUST00000150892.1
ENSMUST00000126216.1
CAP-GLY domain containing linker protein 3
chr17_-_70849644 0.01 ENSMUST00000134654.1
ENSMUST00000172229.1
ENSMUST00000127719.1
TGFB-induced factor homeobox 1
chr6_-_113434757 0.01 ENSMUST00000113091.1
cell death-inducing DFFA-like effector c
chr8_+_84148025 0.01 ENSMUST00000143833.1
ENSMUST00000118856.1
RIKEN cDNA 4930432K21 gene
chr5_+_32136458 0.00 ENSMUST00000031017.9
fos-like antigen 2
chrM_+_10167 0.00 ENSMUST00000082414.1
mitochondrially encoded NADH dehydrogenase 4
chr11_+_98753512 0.00 ENSMUST00000124072.1
thyroid hormone receptor alpha
chr11_+_95414078 0.00 ENSMUST00000107724.2
ENSMUST00000150884.1
ENSMUST00000107722.1
ENSMUST00000127713.1
speckle-type POZ protein
chr15_+_80623499 0.00 ENSMUST00000043149.7
GRB2-related adaptor protein 2
chr19_-_19001099 0.00 ENSMUST00000040153.8
ENSMUST00000112828.1
RAR-related orphan receptor beta

Network of associatons between targets according to the STRING database.

First level regulatory network of Tbx1_Eomes

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 0.9 GO:0042662 negative regulation of mesodermal cell fate specification(GO:0042662) cardiac cell fate determination(GO:0060913)
0.4 1.6 GO:0061010 gall bladder development(GO:0061010)
0.3 1.4 GO:0008078 mesodermal cell migration(GO:0008078)
0.2 0.5 GO:0002355 detection of tumor cell(GO:0002355)
0.1 0.4 GO:2000852 corticosterone secretion(GO:0035934) regulation of corticosterone secretion(GO:2000852)
0.1 0.8 GO:0033762 response to glucagon(GO:0033762)
0.1 0.5 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.1 0.3 GO:0060300 regulation of cytokine activity(GO:0060300)
0.1 1.1 GO:0015868 purine ribonucleotide transport(GO:0015868)
0.1 0.2 GO:1990918 double-strand break repair involved in meiotic recombination(GO:1990918)
0.1 1.1 GO:0010457 centriole-centriole cohesion(GO:0010457)
0.1 0.4 GO:0060455 negative regulation of gastric acid secretion(GO:0060455)
0.1 0.3 GO:1900108 negative regulation of nodal signaling pathway(GO:1900108)
0.1 0.7 GO:0010572 positive regulation of platelet activation(GO:0010572)
0.1 0.6 GO:0090009 somite rostral/caudal axis specification(GO:0032525) primitive streak formation(GO:0090009)
0.1 0.2 GO:0035621 ER to Golgi ceramide transport(GO:0035621) ceramide transport(GO:0035627)
0.1 0.5 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.1 0.3 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.0 0.8 GO:0048012 hepatocyte growth factor receptor signaling pathway(GO:0048012)
0.0 0.1 GO:0032474 otolith morphogenesis(GO:0032474)
0.0 0.1 GO:0040030 regulation of molecular function, epigenetic(GO:0040030)
0.0 0.2 GO:1902303 negative regulation of potassium ion export(GO:1902303)
0.0 0.1 GO:0061026 cardiac muscle tissue regeneration(GO:0061026)
0.0 0.3 GO:0060708 spongiotrophoblast differentiation(GO:0060708)
0.0 0.2 GO:0003219 cardiac right ventricle formation(GO:0003219)
0.0 0.2 GO:0045196 establishment or maintenance of neuroblast polarity(GO:0045196) establishment of neuroblast polarity(GO:0045200)
0.0 0.1 GO:0017055 negative regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0017055)
0.0 0.1 GO:0032765 positive regulation of mast cell cytokine production(GO:0032765) Fc-epsilon receptor signaling pathway(GO:0038095) vestibular reflex(GO:0060005)
0.0 0.2 GO:1903849 regulation of aorta morphogenesis(GO:1903847) positive regulation of aorta morphogenesis(GO:1903849)
0.0 0.2 GO:0042904 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.0 0.4 GO:0019236 response to pheromone(GO:0019236)
0.0 1.2 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.1 GO:1900224 regulation of nodal signaling pathway involved in determination of left/right asymmetry(GO:1900145) regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900175) positive regulation of nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry(GO:1900224) positive regulation of mesoderm development(GO:2000382)
0.0 0.1 GO:0032763 regulation of mast cell cytokine production(GO:0032763)
0.0 0.1 GO:0051385 response to mineralocorticoid(GO:0051385)
0.0 0.2 GO:0042663 regulation of endodermal cell fate specification(GO:0042663)
0.0 0.1 GO:1900247 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
0.0 0.3 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 0.2 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 0.6 GO:0035335 peptidyl-tyrosine dephosphorylation(GO:0035335)
0.0 0.2 GO:0040031 snRNA modification(GO:0040031)
0.0 0.1 GO:0015766 disaccharide transport(GO:0015766) sucrose transport(GO:0015770) oligosaccharide transport(GO:0015772)
0.0 0.1 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
0.0 0.4 GO:0046697 decidualization(GO:0046697)
0.0 1.0 GO:0001919 regulation of receptor recycling(GO:0001919)
0.0 0.2 GO:0002158 osteoclast proliferation(GO:0002158)
0.0 0.3 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.0 0.2 GO:2000035 regulation of stem cell division(GO:2000035)
0.0 0.1 GO:0061113 pancreas morphogenesis(GO:0061113)
0.0 0.2 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.1 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.0 0.2 GO:1901386 negative regulation of voltage-gated calcium channel activity(GO:1901386)
0.0 0.1 GO:0070163 adiponectin secretion(GO:0070162) regulation of adiponectin secretion(GO:0070163) negative regulation of monocyte chemotactic protein-1 production(GO:0071638)
0.0 0.7 GO:0006493 protein O-linked glycosylation(GO:0006493)
0.0 0.1 GO:0007220 Notch receptor processing(GO:0007220)
0.0 0.2 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.0 0.2 GO:0090050 positive regulation of cell migration involved in sprouting angiogenesis(GO:0090050)
0.0 0.5 GO:0000186 activation of MAPKK activity(GO:0000186)
0.0 0.0 GO:0050916 sensory perception of sweet taste(GO:0050916)
0.0 0.1 GO:0010908 regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010908) positive regulation of heparan sulfate proteoglycan biosynthetic process(GO:0010909) canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition(GO:0044334)
0.0 0.1 GO:0031915 positive regulation of synaptic plasticity(GO:0031915)
0.0 0.2 GO:0060481 lobar bronchus epithelium development(GO:0060481)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.2 GO:1990769 proximal neuron projection(GO:1990769)
0.2 0.7 GO:0031092 platelet alpha granule membrane(GO:0031092)
0.1 1.0 GO:0043083 synaptic cleft(GO:0043083)
0.1 1.2 GO:0005922 connexon complex(GO:0005922)
0.1 0.4 GO:0005638 lamin filament(GO:0005638)
0.0 0.2 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.0 0.3 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.0 0.1 GO:0034774 secretory granule lumen(GO:0034774) cytoplasmic membrane-bounded vesicle lumen(GO:0060205)
0.0 2.2 GO:0001750 photoreceptor outer segment(GO:0001750)
0.0 0.5 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.1 GO:0071144 activin responsive factor complex(GO:0032444) SMAD2-SMAD3 protein complex(GO:0071144)
0.0 0.1 GO:0070765 gamma-secretase complex(GO:0070765)
0.0 0.2 GO:0071564 npBAF complex(GO:0071564)
0.0 0.1 GO:0071203 WASH complex(GO:0071203)
0.0 0.0 GO:0099524 region of cytosol(GO:0099522) postsynaptic cytosol(GO:0099524)
0.0 1.3 GO:0005814 centriole(GO:0005814)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0004967 glucagon receptor activity(GO:0004967)
0.2 0.7 GO:0042806 fucose binding(GO:0042806)
0.2 0.5 GO:0031752 D3 dopamine receptor binding(GO:0031750) D5 dopamine receptor binding(GO:0031752)
0.1 1.6 GO:0008301 DNA binding, bending(GO:0008301)
0.1 1.0 GO:0004971 AMPA glutamate receptor activity(GO:0004971)
0.1 0.7 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.1 0.5 GO:0019828 aspartic-type endopeptidase inhibitor activity(GO:0019828)
0.1 0.3 GO:0019970 interleukin-11 receptor activity(GO:0004921) interleukin-11 binding(GO:0019970)
0.1 0.3 GO:0038100 nodal binding(GO:0038100)
0.1 1.2 GO:0005243 gap junction channel activity(GO:0005243)
0.1 0.2 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.1 0.2 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.1 0.2 GO:0003918 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.1 0.8 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.3 GO:0005047 signal recognition particle binding(GO:0005047)
0.0 0.3 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.2 GO:0050436 microfibril binding(GO:0050436)
0.0 0.7 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.4 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.0 0.1 GO:0002153 steroid receptor RNA activator RNA binding(GO:0002153)
0.0 0.2 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.2 GO:0097001 ceramide binding(GO:0097001)
0.0 0.2 GO:1902282 phosphorelay sensor kinase activity(GO:0000155) voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1902282)
0.0 0.3 GO:0036122 BMP binding(GO:0036122)
0.0 0.1 GO:0005171 hepatocyte growth factor receptor binding(GO:0005171)
0.0 1.2 GO:0001786 phosphatidylserine binding(GO:0001786)
0.0 0.1 GO:0008515 sucrose:proton symporter activity(GO:0008506) sucrose transmembrane transporter activity(GO:0008515) disaccharide transmembrane transporter activity(GO:0015154) oligosaccharide transmembrane transporter activity(GO:0015157)
0.0 0.2 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 0.1 GO:0030618 transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity(GO:0030618)
0.0 0.1 GO:0038132 neuregulin binding(GO:0038132)
0.0 0.1 GO:0086038 calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential(GO:0086038)
0.0 0.4 GO:0005521 lamin binding(GO:0005521)
0.0 0.4 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.7 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 0.7 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 REACTOME GAP JUNCTION ASSEMBLY Genes involved in Gap junction assembly
0.0 1.0 REACTOME UNBLOCKING OF NMDA RECEPTOR GLUTAMATE BINDING AND ACTIVATION Genes involved in Unblocking of NMDA receptor, glutamate binding and activation
0.0 0.2 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.3 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.3 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.1 REACTOME SIGNALING BY EGFR IN CANCER Genes involved in Signaling by EGFR in Cancer
0.0 1.0 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors
0.0 0.2 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 0.6 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 0.2 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.4 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL
0.0 1.0 REACTOME REGULATION OF INSULIN SECRETION Genes involved in Regulation of Insulin Secretion
0.0 0.5 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.7 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.3 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.5 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.2 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE