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2D miR_HR1_12

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Results for Tbx20

Z-value: 0.37

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Transcription factors associated with Tbx20

Gene Symbol Gene ID Gene Info
ENSMUSG00000031965.8 T-box 20

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Tbx20mm10_v2_chr9_-_24774276_247743030.872.7e-04Click!

Activity profile of Tbx20 motif

Sorted Z-values of Tbx20 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr4_-_118437331 1.23 ENSMUST00000006565.6
cell division cycle 20
chr7_+_79660196 1.19 ENSMUST00000035977.7
TOPBP1-interacting checkpoint and replication regulator
chr19_+_38055002 1.06 ENSMUST00000096096.4
ENSMUST00000116506.1
ENSMUST00000169673.1
centrosomal protein 55
chr12_+_51348265 0.62 ENSMUST00000119211.1
G2/M-phase specific E3 ubiquitin ligase
chr12_+_51348370 0.59 ENSMUST00000121521.1
G2/M-phase specific E3 ubiquitin ligase
chr8_-_22694061 0.40 ENSMUST00000131767.1
inhibitor of kappaB kinase beta
chr6_+_15196949 0.33 ENSMUST00000151301.1
ENSMUST00000131414.1
ENSMUST00000140557.1
ENSMUST00000115469.1
forkhead box P2
chr17_-_12868126 0.30 ENSMUST00000089015.3
MAS1 oncogene
chr11_-_23770953 0.28 ENSMUST00000102864.3
reticuloendotheliosis oncogene
chr8_+_83900706 0.21 ENSMUST00000045393.8
ENSMUST00000132500.1
ENSMUST00000152978.1
latrophilin 1
chr15_-_78495059 0.17 ENSMUST00000089398.1
interleukin 2 receptor, beta chain
chr9_+_35669624 0.16 ENSMUST00000118254.1
prostate and testis expressed 2
chr8_-_85555261 0.15 ENSMUST00000034138.5
DnaJ (Hsp40) homolog, subfamily A, member 2
chr17_-_23745829 0.10 ENSMUST00000046525.8
kringle containing transmembrane protein 2
chr7_-_105787544 0.09 ENSMUST00000078482.5
ENSMUST00000154659.1
dachsous 1 (Drosophila)
chr9_-_73039644 0.08 ENSMUST00000184389.1
phosphatidylinositol glycan anchor biosynthesis, class B
chr8_-_3694167 0.08 ENSMUST00000005678.4
Fc receptor, IgE, low affinity II, alpha polypeptide
chr15_-_102516806 0.07 ENSMUST00000169162.1
ENSMUST00000023812.2
ENSMUST00000165174.1
ENSMUST00000169367.1
ENSMUST00000169377.1
mitogen-activated protein kinase kinase kinase 12
chr7_-_105787567 0.07 ENSMUST00000144189.1
dachsous 1 (Drosophila)
chr3_-_144202300 0.05 ENSMUST00000121796.1
ENSMUST00000121112.1
LIM domain only 4
chr9_+_98296556 0.04 ENSMUST00000035031.6
ENSMUST00000112935.1
nicotinamide nucleotide adenylyltransferase 3

Network of associatons between targets according to the STRING database.

First level regulatory network of Tbx20

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.2 GO:0098763 mitotic cell cycle phase(GO:0098763)
0.1 1.2 GO:0030174 regulation of DNA-dependent DNA replication initiation(GO:0030174)
0.1 0.4 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.1 1.1 GO:0000920 cell separation after cytokinesis(GO:0000920)
0.0 0.2 GO:0072137 condensed mesenchymal cell proliferation(GO:0072137)
0.0 0.3 GO:0045084 positive regulation of interleukin-12 biosynthetic process(GO:0045084)
0.0 0.3 GO:0060732 positive regulation of inositol phosphate biosynthetic process(GO:0060732)
0.0 0.3 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.0 0.1 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 GO:0090543 Flemming body(GO:0090543)
0.0 1.2 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.3 GO:0033256 I-kappaB/NF-kappaB complex(GO:0033256)
0.0 0.4 GO:0008385 IkappaB kinase complex(GO:0008385)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.2 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.1 0.4 GO:0008384 IkappaB kinase activity(GO:0008384)
0.1 0.2 GO:0004911 interleukin-2 receptor activity(GO:0004911)
0.0 0.3 GO:0001595 angiotensin receptor activity(GO:0001595)
0.0 0.1 GO:0019863 IgE binding(GO:0019863)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 1.2 PID PLK1 PATHWAY PLK1 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.2 REACTOME CONVERSION FROM APC C CDC20 TO APC C CDH1 IN LATE ANAPHASE Genes involved in Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
0.0 0.4 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1