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2D miR_HR1_12

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Results for Hoxa10

Z-value: 0.96

Motif logo

Transcription factors associated with Hoxa10

Gene Symbol Gene ID Gene Info
ENSMUSG00000000938.11 homeobox A10

Activity profile of Hoxa10 motif

Sorted Z-values of Hoxa10 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr8_-_33747724 3.33 ENSMUST00000179364.1
small integral membrane protein 18
chr19_+_38930909 2.19 ENSMUST00000025965.5
helicase, lymphoid specific
chr9_+_53771499 1.85 ENSMUST00000048670.8
solute carrier family 35, member F2
chr9_+_55326913 1.79 ENSMUST00000085754.3
ENSMUST00000034862.4
expressed sequence AI118078
chr12_-_72917872 1.65 ENSMUST00000044000.5
RIKEN cDNA 4930447C04 gene
chr9_+_108560422 1.64 ENSMUST00000081111.8
inosine 5'-phosphate dehydrogenase 2
chr14_+_115042752 1.47 ENSMUST00000134140.2
Mir17 host gene 1 (non-protein coding)
chr2_-_51149100 1.32 ENSMUST00000154545.1
ENSMUST00000017288.2
Rho family GTPase 3
chr19_+_30232921 1.25 ENSMUST00000025797.5
mannose-binding lectin (protein C) 2
chr15_+_62039216 1.23 ENSMUST00000183297.1
plasmacytoma variant translocation 1
chr1_+_74713551 1.14 ENSMUST00000027356.5
cytochrome P450, family 27, subfamily a, polypeptide 1
chr3_+_94398517 1.13 ENSMUST00000050975.3
leucine rich repeat and Ig domain containing 4
chr17_+_29093763 1.12 ENSMUST00000023829.6
cyclin-dependent kinase inhibitor 1A (P21)
chr2_-_110950923 1.03 ENSMUST00000099623.3
anoctamin 3
chr9_-_44251464 1.01 ENSMUST00000034618.4
PDZ domain containing 3
chr2_-_164638789 1.00 ENSMUST00000109336.1
WAP four-disulfide core domain 16
chr5_-_123666682 0.82 ENSMUST00000149410.1
CAP-GLY domain containing linker protein 1
chr12_-_69198419 0.72 ENSMUST00000021356.5
dynein, axonemal assembly factor 2
chr6_-_24528013 0.69 ENSMUST00000023851.5
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 5
chr14_-_89898466 0.69 ENSMUST00000081204.4
predicted gene 10110
chr18_+_60774675 0.65 ENSMUST00000118551.1
ribosomal protein S14
chr13_+_23581563 0.64 ENSMUST00000102968.1
histone cluster 1, H4d
chr15_+_3270767 0.63 ENSMUST00000082424.4
ENSMUST00000159158.1
ENSMUST00000159216.1
ENSMUST00000160311.1
selenoprotein P, plasma, 1
chr4_-_91376433 0.62 ENSMUST00000107109.2
ENSMUST00000107111.2
ENSMUST00000107120.1
ELAV (embryonic lethal, abnormal vision, Drosophila)-like 2 (Hu antigen B)
chr11_+_85312164 0.59 ENSMUST00000127717.1
protein phosphatase 1D magnesium-dependent, delta isoform
chr2_+_15049395 0.58 ENSMUST00000017562.6
ADP-ribosylation factor-like 5B
chr9_+_62342449 0.57 ENSMUST00000156461.1
acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
chr1_+_40515362 0.55 ENSMUST00000027237.5
interleukin 18 receptor accessory protein
chr2_-_73452666 0.55 ENSMUST00000151939.1
WAS/WASL interacting protein family, member 1
chr7_-_126160992 0.53 ENSMUST00000164741.1
exportin 6
chr13_-_74376566 0.53 ENSMUST00000091481.2
zinc finger protein 72
chr1_+_59684949 0.53 ENSMUST00000027174.3
NOP58 ribonucleoprotein
chr17_+_6079928 0.49 ENSMUST00000100955.2
general transcription factor IIH, polypeptide 5
chr15_+_59374198 0.48 ENSMUST00000079703.3
ENSMUST00000168722.1
non-SMC element 2 homolog (MMS21, S. cerevisiae)
chr10_-_19014549 0.48 ENSMUST00000146388.1
tumor necrosis factor, alpha-induced protein 3
chr3_-_94436574 0.48 ENSMUST00000029787.4
ornithine decarboxylase antizyme 3
chr4_+_42629719 0.47 ENSMUST00000166898.2
predicted gene 2564
chr11_+_87109221 0.47 ENSMUST00000020794.5
spindle and kinetochore associated complex subunit 2
chr6_+_24528144 0.47 ENSMUST00000031696.3
ankyrin repeat and SOCS box-containing 15
chr5_+_105415738 0.46 ENSMUST00000112707.1
leucine rich repeat containing 8 family, member B
chr1_+_66321708 0.45 ENSMUST00000114013.1
microtubule-associated protein 2
chr18_+_60774510 0.45 ENSMUST00000025511.3
ribosomal protein S14
chrM_+_14138 0.45 ENSMUST00000082421.1
mitochondrially encoded cytochrome b
chr10_-_127030789 0.44 ENSMUST00000120547.1
ENSMUST00000152054.1
Ts translation elongation factor, mitochondrial
chr3_-_137552622 0.44 ENSMUST00000068546.5
predicted gene 4861
chr9_-_51328898 0.43 ENSMUST00000039959.4
RIKEN cDNA 1810046K07 gene
chr17_-_81649607 0.43 ENSMUST00000163680.2
ENSMUST00000086538.3
ENSMUST00000163123.1
solute carrier family 8 (sodium/calcium exchanger), member 1
chr13_+_44840686 0.43 ENSMUST00000173906.1
jumonji, AT rich interactive domain 2
chr13_-_99516537 0.41 ENSMUST00000064762.4
microtubule-associated protein 1B
chr7_+_43408187 0.41 ENSMUST00000005592.6
sialic acid binding Ig-like lectin G
chr6_-_83677807 0.41 ENSMUST00000037882.6
CD207 antigen
chrM_-_14060 0.40 ENSMUST00000082419.1
mitochondrially encoded NADH dehydrogenase 6
chr2_-_34755229 0.40 ENSMUST00000102800.1
GTPase activating protein and VPS9 domains 1
chr9_-_86464944 0.39 ENSMUST00000034986.7
ubiquitin-conjugating enzyme E2C binding protein
chr18_+_37411674 0.39 ENSMUST00000051126.2
protocadherin beta 10
chr6_-_3494587 0.38 ENSMUST00000049985.8
HEPACAM family member 2
chr5_-_87092546 0.37 ENSMUST00000132667.1
ENSMUST00000145617.1
ENSMUST00000094649.4
UDP glucuronosyltransferase 2 family, polypeptide B36
chr9_-_50739365 0.37 ENSMUST00000117093.1
ENSMUST00000121634.1
DIX domain containing 1
chr10_-_111997204 0.37 ENSMUST00000074805.5
GLI pathogenesis-related 1 (glioma)
chr16_+_38362205 0.37 ENSMUST00000023494.6
popeye domain containing 2
chrX_-_136741155 0.36 ENSMUST00000166930.1
ENSMUST00000113095.1
ENSMUST00000155207.1
ENSMUST00000080411.6
ENSMUST00000169418.1
mortality factor 4 like 2
chr5_+_62813823 0.36 ENSMUST00000170704.1
predicted gene, 17384
chr2_-_79908428 0.35 ENSMUST00000102652.3
ENSMUST00000102651.3
phosphodiesterase 1A, calmodulin-dependent
chr17_+_6079786 0.34 ENSMUST00000039487.3
general transcription factor IIH, polypeptide 5
chr13_+_58281183 0.34 ENSMUST00000180882.1
ENSMUST00000180452.1
predicted gene, 26555
chr12_+_84361968 0.34 ENSMUST00000021661.6
coenzyme Q6 homolog (yeast)
chr8_+_110618577 0.33 ENSMUST00000034190.9
Vac14 homolog (S. cerevisiae)
chr9_+_13765970 0.33 ENSMUST00000152532.1
myotubularin related protein 2
chr19_+_43440404 0.33 ENSMUST00000165311.1
cyclin M1
chr3_+_136670076 0.31 ENSMUST00000070198.7
protein phosphatase 3, catalytic subunit, alpha isoform
chr5_+_64160207 0.31 ENSMUST00000101195.2
TBC1 domain family, member 1
chrM_+_3906 0.30 ENSMUST00000082396.1
mitochondrially encoded NADH dehydrogenase 2
chrX_+_166170449 0.30 ENSMUST00000130880.2
ENSMUST00000056410.4
ENSMUST00000096252.3
ENSMUST00000087169.4
gem (nuclear organelle) associated protein 8
chr18_-_12860197 0.30 ENSMUST00000124570.1
oxysterol binding protein-like 1A
chr9_+_35669624 0.29 ENSMUST00000118254.1
prostate and testis expressed 2
chr1_+_165769392 0.29 ENSMUST00000040298.4
cellular repressor of E1A-stimulated genes 1
chr16_+_38362234 0.27 ENSMUST00000114739.1
popeye domain containing 2
chr4_+_33132503 0.27 ENSMUST00000029947.5
gamma-aminobutyric acid (GABA) C receptor, subunit rho 1
chr2_+_31759993 0.26 ENSMUST00000124089.1
c-abl oncogene 1, non-receptor tyrosine kinase
chr2_-_37647199 0.26 ENSMUST00000028279.3
spermatid perinuclear RNA binding protein
chr10_-_116549101 0.25 ENSMUST00000164088.1
CCR4-NOT transcription complex, subunit 2
chr8_+_46492789 0.25 ENSMUST00000110371.1
acyl-CoA synthetase long-chain family member 1
chr3_-_14778452 0.24 ENSMUST00000094365.4
carbonic anhydrase 1
chr10_-_51631458 0.24 ENSMUST00000020062.3
G protein-coupled receptor, family C, group 6, member A
chrX_+_96455359 0.23 ENSMUST00000033553.7
hephaestin
chr2_-_79908389 0.23 ENSMUST00000090756.4
phosphodiesterase 1A, calmodulin-dependent
chr2_-_114201416 0.23 ENSMUST00000050668.3
zinc finger protein 770
chr6_+_54264839 0.23 ENSMUST00000146114.1
chimerin (chimaerin) 2
chr11_+_3330401 0.22 ENSMUST00000045153.4
phosphoinositide-3-kinase interacting protein 1
chr4_-_11981265 0.22 ENSMUST00000098260.2
predicted gene 10604
chr8_+_71597648 0.21 ENSMUST00000143662.1
family with sequence similarity 129, member C
chr13_+_18717289 0.21 ENSMUST00000072961.4
vacuolar protein sorting 41 (yeast)
chr13_+_23695791 0.21 ENSMUST00000041052.2
histone cluster 1, H1t
chr2_+_177508570 0.21 ENSMUST00000108940.2
predicted gene 14403
chr18_-_39487096 0.20 ENSMUST00000097592.2
ENSMUST00000115571.1
nuclear receptor subfamily 3, group C, member 1
chr16_+_32419696 0.20 ENSMUST00000014220.8
ENSMUST00000080316.7
Tctex1 domain containing 2
chr17_+_5799616 0.19 ENSMUST00000181392.1
RIKEN cDNA 3300005D01 gene
chr2_-_77946331 0.19 ENSMUST00000111821.2
ENSMUST00000111818.1
CWC22 spliceosome-associated protein homolog (S. cerevisiae)
chr11_-_100762928 0.19 ENSMUST00000107360.2
ENSMUST00000055083.3
hypocretin
chr11_-_101417615 0.19 ENSMUST00000070395.8
alanyl-tRNA synthetase domain containing 1
chr2_+_102658640 0.19 ENSMUST00000080210.3
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr6_-_67491849 0.18 ENSMUST00000118364.1
interleukin 23 receptor
chr10_-_58675631 0.18 ENSMUST00000003312.4
ectodysplasin-A receptor
chr5_+_121777929 0.18 ENSMUST00000160821.1
ataxin 2
chrX_+_112615301 0.18 ENSMUST00000122805.1
zinc finger protein 711
chr8_+_93810832 0.17 ENSMUST00000034198.8
ENSMUST00000125716.1
guanine nucleotide binding protein, alpha O
chr2_-_42653598 0.17 ENSMUST00000052550.6
low density lipoprotein-related protein 1B (deleted in tumors)
chr9_-_100506844 0.17 ENSMUST00000112874.3
non-catalytic region of tyrosine kinase adaptor protein 1
chr2_+_83812567 0.16 ENSMUST00000051454.3
family with sequence similarity 171, member B
chr2_-_73625731 0.16 ENSMUST00000070579.6
chimerin (chimaerin) 1
chr11_+_44617310 0.16 ENSMUST00000081265.5
ENSMUST00000101326.3
ENSMUST00000109268.1
early B cell factor 1
chrX_+_10252361 0.16 ENSMUST00000115528.2
ornithine transcarbamylase
chr4_+_115057410 0.16 ENSMUST00000136946.1
T cell acute lymphocytic leukemia 1
chr6_-_99044414 0.15 ENSMUST00000177507.1
ENSMUST00000123992.1
forkhead box P1
chr2_+_110721587 0.15 ENSMUST00000111017.2
mucin 15
chr4_-_82850721 0.15 ENSMUST00000139401.1
zinc finger, DHHC domain containing 21
chr17_+_5799491 0.15 ENSMUST00000181484.1
RIKEN cDNA 3300005D01 gene
chr6_-_99028874 0.15 ENSMUST00000154163.2
forkhead box P1
chr2_-_77946375 0.14 ENSMUST00000065889.3
CWC22 spliceosome-associated protein homolog (S. cerevisiae)
chr8_+_58912257 0.14 ENSMUST00000160055.1
cDNA sequence BC030500
chr1_-_63686904 0.13 ENSMUST00000090313.4
dystrotelin
chr2_+_68117713 0.13 ENSMUST00000112346.2
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1
chr7_+_102229999 0.13 ENSMUST00000120119.1
post-GPI attachment to proteins 2
chr19_+_29925107 0.12 ENSMUST00000120388.2
ENSMUST00000144528.1
ENSMUST00000177518.1
interleukin 33
chr18_-_15063560 0.12 ENSMUST00000168989.1
potassium channel tetramerisation domain containing 1
chr11_-_99422252 0.12 ENSMUST00000017741.3
keratin 12
chrX_+_139086226 0.12 ENSMUST00000033625.1
RIKEN cDNA 4930513O06 gene
chrX_+_10252305 0.12 ENSMUST00000049910.6
ornithine transcarbamylase
chr2_-_34826071 0.12 ENSMUST00000113077.1
ENSMUST00000028220.3
F-box and WD-40 domain protein 2
chr3_-_30509752 0.12 ENSMUST00000172697.1
MDS1 and EVI1 complex locus
chr11_+_78920787 0.11 ENSMUST00000018610.6
nitric oxide synthase 2, inducible
chr8_-_54718664 0.11 ENSMUST00000144711.2
ENSMUST00000093510.2
WD repeat domain 17
chr13_-_90089060 0.11 ENSMUST00000161396.1
X-ray repair complementing defective repair in Chinese hamster cells 4
chr2_-_174464063 0.11 ENSMUST00000016396.7
ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit
chr18_-_34651703 0.10 ENSMUST00000025228.5
ENSMUST00000133181.1
CDC23 cell division cycle 23
chr1_+_193173469 0.10 ENSMUST00000161235.1
ENSMUST00000110831.2
ENSMUST00000178744.1
RIKEN cDNA A130010J15 gene
chrX_-_43274786 0.09 ENSMUST00000016294.7
teneurin transmembrane protein 1
chr2_-_149798701 0.09 ENSMUST00000148202.1
ENSMUST00000139471.1
predicted gene 14133
chr15_-_54919961 0.08 ENSMUST00000167541.2
ENSMUST00000041591.9
ENSMUST00000173516.1
ectonucleotide pyrophosphatase/phosphodiesterase 2
chr14_-_54686060 0.07 ENSMUST00000125265.1
apoptotic chromatin condensation inducer 1
chr4_-_14796052 0.07 ENSMUST00000108276.1
ENSMUST00000023917.1
leucine rich repeat containing 69
chr13_-_60897439 0.07 ENSMUST00000171347.1
ENSMUST00000021884.8
cytotoxic T lymphocyte-associated protein 2 beta
chr2_-_176319494 0.07 ENSMUST00000108961.3
predicted gene 11009
chr2_-_91255995 0.07 ENSMUST00000180732.1
predicted gene, 17281
chr9_-_96478596 0.07 ENSMUST00000071301.4
ring finger protein 7
chr8_+_83666827 0.06 ENSMUST00000019608.5
prostaglandin E receptor 1 (subtype EP1)
chr5_-_151586924 0.06 ENSMUST00000165928.1
vomeronasal 2, receptor 18
chr2_-_34826187 0.06 ENSMUST00000113075.1
ENSMUST00000113080.2
ENSMUST00000091020.3
F-box and WD-40 domain protein 2
chr1_+_153874335 0.06 ENSMUST00000055314.3
predicted gene 5531
chr19_+_4711153 0.06 ENSMUST00000008991.6
spectrin beta, non-erythrocytic 2
chr7_-_144470714 0.05 ENSMUST00000033407.6
cortactin
chr13_+_23839401 0.05 ENSMUST00000039721.7
ENSMUST00000166467.1
solute carrier family 17 (sodium phosphate), member 3
chr5_-_21701332 0.05 ENSMUST00000115217.1
ENSMUST00000060899.8
N-acyl phosphatidylethanolamine phospholipase D
chr3_+_132634725 0.05 ENSMUST00000163241.1
predicted gene 5549
chr13_+_23839445 0.05 ENSMUST00000091698.4
ENSMUST00000110422.1
solute carrier family 17 (sodium phosphate), member 3
chr3_+_26331150 0.04 ENSMUST00000099182.2
RIKEN cDNA A830092H15 gene
chr5_+_24394388 0.04 ENSMUST00000115074.1
ATP-binding cassette, sub-family B (MDR/TAP), member 8
chr11_+_52004340 0.04 ENSMUST00000109076.1
cyclin-dependent kinase-like 3
chr13_+_24614608 0.04 ENSMUST00000091694.3
family with sequence similarity 65, member B
chr15_-_54920115 0.04 ENSMUST00000171545.1
ectonucleotide pyrophosphatase/phosphodiesterase 2
chr17_-_6079693 0.04 ENSMUST00000024570.5
ENSMUST00000097432.3
serine active site containing 1
chr4_+_43406435 0.04 ENSMUST00000098106.2
ENSMUST00000139198.1
RUN and SH3 domain containing 2
chr15_+_4727265 0.04 ENSMUST00000162350.1
complement component 6
chr15_+_85510812 0.04 ENSMUST00000079690.2
predicted pseudogene 4825
chr1_-_82768449 0.04 ENSMUST00000027331.2
transmembrane 4 L six family member 20
chr9_+_38719024 0.04 ENSMUST00000129598.1
von Willebrand factor A domain containing 5A
chr6_-_122856151 0.03 ENSMUST00000042081.8
complement component 3a receptor 1
chrX_-_49886401 0.03 ENSMUST00000070304.2
olfactory receptor 1322
chr18_+_53551594 0.03 ENSMUST00000115398.1
PR domain containing 6
chr17_+_88626549 0.02 ENSMUST00000163588.1
ENSMUST00000064035.6
stonin 1
chr1_+_167618246 0.02 ENSMUST00000111380.1
retinoid X receptor gamma
chr17_-_25844417 0.02 ENSMUST00000176591.1
ras homolog gene family, member T2
chrX_+_112604274 0.02 ENSMUST00000071814.6
zinc finger protein 711
chr2_+_31759932 0.01 ENSMUST00000028190.6
c-abl oncogene 1, non-receptor tyrosine kinase
chr7_+_29238323 0.01 ENSMUST00000108238.1
ENSMUST00000032809.3
ENSMUST00000138128.1
Yip1 interacting factor homolog B (S. cerevisiae)
chr3_+_66985680 0.01 ENSMUST00000065047.6
arginine/serine-rich coiled-coil 1
chr2_+_4300462 0.01 ENSMUST00000175669.1
FERM domain containing 4A
chr17_+_88626569 0.01 ENSMUST00000150023.1
stonin 1
chr10_-_11082287 0.01 ENSMUST00000105561.2
ENSMUST00000044306.6
glutamate receptor, metabotropic 1
chr9_-_112232449 0.00 ENSMUST00000035085.5
cyclic AMP-regulated phosphoprotein, 21
chr3_-_123672321 0.00 ENSMUST00000172537.1
ENSMUST00000029602.6
N-deacetylase/N-sulfotransferase (heparan glucosaminyl) 3
chr1_+_127729405 0.00 ENSMUST00000038006.6
amino carboxymuconate semialdehyde decarboxylase
chr11_-_69822144 0.00 ENSMUST00000045771.6
sperm maturation 1

Network of associatons between targets according to the STRING database.

First level regulatory network of Hoxa10

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:0010705 meiotic DNA double-strand break processing involved in reciprocal meiotic recombination(GO:0010705)
0.3 1.6 GO:0006177 GMP biosynthetic process(GO:0006177)
0.3 2.2 GO:0031508 pericentric heterochromatin assembly(GO:0031508)
0.2 0.8 GO:0044861 protein transport into plasma membrane raft(GO:0044861)
0.2 1.0 GO:0061590 calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591)
0.2 0.5 GO:0034093 positive regulation of maintenance of sister chromatid cohesion(GO:0034093) positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184)
0.2 0.5 GO:0002631 regulation of granuloma formation(GO:0002631) negative regulation of granuloma formation(GO:0002632) regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429) tolerance induction to lipopolysaccharide(GO:0072573)
0.2 1.2 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.1 0.5 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.1 1.1 GO:0071493 cellular response to UV-B(GO:0071493)
0.1 0.4 GO:0070125 mitochondrial translational elongation(GO:0070125)
0.1 0.6 GO:0060931 sinoatrial node cell development(GO:0060931)
0.1 0.3 GO:0010615 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244)
0.1 1.0 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.1 0.8 GO:0006362 transcription elongation from RNA polymerase I promoter(GO:0006362)
0.1 0.3 GO:1900275 negative regulation of phospholipase C activity(GO:1900275)
0.1 0.3 GO:0042450 arginine biosynthetic process via ornithine(GO:0042450)
0.1 0.5 GO:0048254 snoRNA localization(GO:0048254)
0.1 0.4 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.1 0.4 GO:0033762 response to glucagon(GO:0033762)
0.1 0.5 GO:0044789 modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
0.1 0.2 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.1 0.2 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.0 1.1 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.2 GO:1902774 late endosome to lysosome transport(GO:1902774)
0.0 0.6 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.3 GO:2000645 negative regulation of myelination(GO:0031642) negative regulation of receptor catabolic process(GO:2000645)
0.0 0.6 GO:0046069 cGMP catabolic process(GO:0046069)
0.0 0.2 GO:1900170 negative regulation of glucocorticoid mediated signaling pathway(GO:1900170)
0.0 0.6 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.0 0.2 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.0 0.2 GO:0051970 negative regulation of transmission of nerve impulse(GO:0051970)
0.0 0.2 GO:0070779 D-aspartate transport(GO:0070777) D-aspartate import(GO:0070779)
0.0 0.4 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.0 0.4 GO:0051574 positive regulation of histone H3-K9 methylation(GO:0051574)
0.0 0.1 GO:0002282 microglial cell activation involved in immune response(GO:0002282)
0.0 0.3 GO:0072619 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.0 0.3 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0 0.1 GO:0031284 positive regulation of guanylate cyclase activity(GO:0031284)
0.0 0.7 GO:0070286 axonemal dynein complex assembly(GO:0070286)
0.0 0.4 GO:0061162 establishment of monopolar cell polarity(GO:0061162) establishment or maintenance of monopolar cell polarity(GO:0061339)
0.0 0.2 GO:0060605 tube lumen cavitation(GO:0060605) salivary gland cavitation(GO:0060662)
0.0 0.2 GO:0044539 long-chain fatty acid import(GO:0044539)
0.0 0.3 GO:0006744 ubiquinone biosynthetic process(GO:0006744)
0.0 0.1 GO:0034638 phosphatidylcholine catabolic process(GO:0034638)
0.0 0.7 GO:0032981 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.3 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.5 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 0.1 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.1 GO:0018230 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.5 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)
0.0 0.1 GO:0015747 urate transport(GO:0015747)
0.0 0.1 GO:0061303 cornea development in camera-type eye(GO:0061303)
0.0 1.1 GO:0051965 positive regulation of synapse assembly(GO:0051965)
0.0 0.1 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.0 0.1 GO:1903998 regulation of eating behavior(GO:1903998)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0070557 PCNA-p21 complex(GO:0070557)
0.2 1.7 GO:0000801 central element(GO:0000801)
0.1 0.8 GO:0044354 pinosome(GO:0044352) macropinosome(GO:0044354)
0.1 0.8 GO:0000439 core TFIIH complex(GO:0000439)
0.1 0.5 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.1 0.5 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.1 0.3 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
0.1 2.2 GO:0005721 pericentric heterochromatin(GO:0005721)
0.1 0.3 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.1 0.3 GO:0005955 calcineurin complex(GO:0005955)
0.1 0.5 GO:0097442 CA3 pyramidal cell dendrite(GO:0097442)
0.0 0.4 GO:0045275 respiratory chain complex III(GO:0045275)
0.0 0.2 GO:0031021 interphase microtubule organizing center(GO:0031021)
0.0 0.5 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.3 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 0.2 GO:0033263 CORVET complex(GO:0033263)
0.0 0.3 GO:0032797 SMN complex(GO:0032797)
0.0 1.9 GO:0031903 peroxisomal membrane(GO:0005778) microbody membrane(GO:0031903)
0.0 1.1 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.6 GO:0000788 nuclear nucleosome(GO:0000788)
0.0 0.4 GO:0043196 varicosity(GO:0043196)
0.0 0.1 GO:0043224 nuclear SCF ubiquitin ligase complex(GO:0043224)
0.0 0.1 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958) DNA ligase IV complex(GO:0032807)
0.0 0.4 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 1.2 GO:0070469 respiratory chain(GO:0070469)
0.0 0.3 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 0.1 GO:0045261 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.0 0.3 GO:1902562 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 0.2 GO:0000164 protein phosphatase type 1 complex(GO:0000164)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.6 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.4 1.1 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.2 1.2 GO:0005534 galactose binding(GO:0005534)
0.2 1.0 GO:0030249 guanylate cyclase regulator activity(GO:0030249)
0.1 0.5 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.1 0.6 GO:0004724 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.1 0.9 GO:0005519 cytoskeletal regulatory protein binding(GO:0005519)
0.1 0.4 GO:0086038 calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential(GO:0086038)
0.1 1.1 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.1 0.6 GO:0004117 calmodulin-dependent cyclic-nucleotide phosphodiesterase activity(GO:0004117) calcium- and calmodulin-regulated 3',5'-cyclic-GMP phosphodiesterase activity(GO:0048101)
0.1 0.6 GO:0004908 interleukin-1 receptor activity(GO:0004908)
0.1 0.8 GO:0000182 rDNA binding(GO:0000182)
0.1 0.3 GO:0016743 carboxyl- or carbamoyltransferase activity(GO:0016743)
0.1 0.5 GO:0001094 TFIID-class transcription factor binding(GO:0001094)
0.1 0.2 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.1 0.2 GO:0043758 acetate-CoA ligase (ADP-forming) activity(GO:0043758)
0.1 0.5 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.1 0.2 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.1 0.4 GO:0016681 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.1 1.0 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)
0.1 0.3 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.8 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.2 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.0 1.2 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.3 GO:0052629 phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity(GO:0052629)
0.0 0.2 GO:0038051 glucocorticoid receptor activity(GO:0004883) transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.0 1.0 GO:0008395 steroid hydroxylase activity(GO:0008395)
0.0 0.1 GO:0034617 tetrahydrobiopterin binding(GO:0034617)
0.0 0.3 GO:0001226 RNA polymerase II transcription corepressor binding(GO:0001226)
0.0 0.5 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.2 GO:0004064 arylesterase activity(GO:0004064)
0.0 0.1 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.0 0.2 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.2 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.2 GO:0051430 corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.0 0.2 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.0 0.1 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.0 0.3 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.1 GO:0004528 phosphodiesterase I activity(GO:0004528) alkylglycerophosphoethanolamine phosphodiesterase activity(GO:0047391)
0.0 0.4 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.4 GO:0032794 GTPase activating protein binding(GO:0032794)
0.0 0.5 GO:0019789 SUMO transferase activity(GO:0019789)
0.0 0.6 GO:0030552 cAMP binding(GO:0030552)
0.0 0.1 GO:0015562 efflux transmembrane transporter activity(GO:0015562)
0.0 0.5 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.3 GO:0071949 FAD binding(GO:0071949)
0.0 0.5 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.2 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 0.3 GO:0004890 GABA-A receptor activity(GO:0004890)
0.0 0.1 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.0 0.4 GO:0043015 gamma-tubulin binding(GO:0043015)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 2.2 PID DELTA NP63 PATHWAY Validated transcriptional targets of deltaNp63 isoforms
0.0 1.5 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.9 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.5 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.2 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 0.3 PID IL23 PATHWAY IL23-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.2 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.1 1.1 REACTOME ENDOGENOUS STEROLS Genes involved in Endogenous sterols
0.1 0.4 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.1 1.6 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.7 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 1.1 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.4 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 1.1 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.6 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 0.6 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.1 REACTOME NITRIC OXIDE STIMULATES GUANYLATE CYCLASE Genes involved in Nitric oxide stimulates guanylate cyclase
0.0 0.6 REACTOME REGULATION OF MRNA STABILITY BY PROTEINS THAT BIND AU RICH ELEMENTS Genes involved in Regulation of mRNA Stability by Proteins that Bind AU-rich Elements
0.0 0.2 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.5 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway
0.0 1.3 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.2 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.4 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor