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2D miR_HR1_12

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Results for Bbx

Z-value: 0.43

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Transcription factors associated with Bbx

Gene Symbol Gene ID Gene Info
ENSMUSG00000022641.9 bobby sox HMG box containing

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Bbxmm10_v2_chr16_-_50330987_50331017-0.556.5e-02Click!

Activity profile of Bbx motif

Sorted Z-values of Bbx motif

Promoter Log-likelihood Transcript Gene Gene Info
chr13_-_52530827 0.75 ENSMUST00000057442.6
DIRAS family, GTP-binding RAS-like 2
chr2_-_152830266 0.43 ENSMUST00000140436.1
BCL2-like 1
chr2_+_58754910 0.37 ENSMUST00000059102.6
uridine phosphorylase 2
chr19_-_11081088 0.35 ENSMUST00000025636.6
membrane-spanning 4-domains, subfamily A, member 8A
chr11_+_59306920 0.34 ENSMUST00000000128.3
ENSMUST00000108783.3
wingless-type MMTV integration site 9A
chr18_+_37421418 0.34 ENSMUST00000053073.4
protocadherin beta 11
chr2_-_152830615 0.34 ENSMUST00000146380.1
ENSMUST00000134902.1
ENSMUST00000134357.1
ENSMUST00000109820.3
BCL2-like 1
chr10_-_86022325 0.32 ENSMUST00000181665.1
RIKEN cDNA A230060F14 gene
chrX_-_150814265 0.28 ENSMUST00000026302.6
ENSMUST00000129768.1
ENSMUST00000112699.2
melanoma antigen, family D, 2
chr1_-_156032948 0.26 ENSMUST00000136397.1
torsin A interacting protein 1
chr16_+_20693263 0.26 ENSMUST00000149543.1
ENSMUST00000118919.1
family with sequence similarity 131, member A
chr13_+_49608030 0.21 ENSMUST00000021822.5
osteoglycin
chrX_+_159708593 0.18 ENSMUST00000080394.6
SH3-domain kinase binding protein 1
chr10_+_86022189 0.17 ENSMUST00000120344.1
ENSMUST00000117597.1
F-box protein 7
chr5_-_108675569 0.16 ENSMUST00000051757.7
solute carrier family 26 (sulfate transporter), member 1
chr8_-_41054771 0.15 ENSMUST00000093534.4
mitochondrial tumor suppressor 1
chr6_+_139621888 0.14 ENSMUST00000032353.8
phosphatidylinositol 3-kinase, C2 domain containing, gamma polypeptide
chr10_+_86021961 0.14 ENSMUST00000130320.1
F-box protein 7
chrX_-_107816238 0.12 ENSMUST00000120722.1
RIKEN cDNA 2610002M06 gene
chr7_+_51880312 0.10 ENSMUST00000145049.1
growth arrest specific 2
chr8_+_45658731 0.08 ENSMUST00000143820.1
ENSMUST00000132139.1
sorbin and SH3 domain containing 2
chr10_-_44458715 0.06 ENSMUST00000039174.4
PR domain containing 1, with ZNF domain
chr8_+_45658273 0.04 ENSMUST00000153798.1
sorbin and SH3 domain containing 2
chr8_-_10928449 0.04 ENSMUST00000040608.3
RIKEN cDNA 3930402G23 gene
chr6_+_124304646 0.04 ENSMUST00000112541.2
ENSMUST00000032234.2
CD163 antigen
chr8_+_45658666 0.04 ENSMUST00000134675.1
ENSMUST00000139869.1
ENSMUST00000126067.1
sorbin and SH3 domain containing 2
chr1_-_13660476 0.03 ENSMUST00000027071.5
lactamase, beta 2
chr19_-_7966000 0.02 ENSMUST00000182102.1
ENSMUST00000075619.4
solute carrier family 22, member 27
chr2_+_136892168 0.01 ENSMUST00000099311.2
SLX4 interacting protein
chr13_-_91807658 0.01 ENSMUST00000022121.6
zinc finger, CCHC domain containing 9

Network of associatons between targets according to the STRING database.

First level regulatory network of Bbx

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0046898 response to cycloheximide(GO:0046898)
0.0 0.3 GO:0070294 renal sodium ion absorption(GO:0070294)
0.0 0.3 GO:1903208 neuron death in response to hydrogen peroxide(GO:0036476) regulation of hydrogen peroxide-induced neuron death(GO:1903207) negative regulation of hydrogen peroxide-induced neuron death(GO:1903208)
0.0 0.2 GO:0019532 oxalate transport(GO:0019532)
0.0 0.3 GO:0071763 nuclear membrane organization(GO:0071763)
0.0 0.3 GO:0032331 negative regulation of chondrocyte differentiation(GO:0032331)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.1 0.3 GO:1990037 Lewy body core(GO:1990037)
0.0 0.4 GO:0045098 type III intermediate filament(GO:0045098)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 GO:0051434 BH3 domain binding(GO:0051434)
0.1 0.4 GO:0004850 uridine phosphorylase activity(GO:0004850)
0.0 0.2 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.0 0.3 GO:0005521 lamin binding(GO:0005521)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.0 0.4 REACTOME PYRIMIDINE CATABOLISM Genes involved in Pyrimidine catabolism
0.0 0.2 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation