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2D miR_HR1_12

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Results for Ddit3

Z-value: 1.76

Motif logo

Transcription factors associated with Ddit3

Gene Symbol Gene ID Gene Info
ENSMUSG00000025408.9 DNA-damage inducible transcript 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Ddit3mm10_v2_chr10_+_127290774_1272908030.691.2e-02Click!

Activity profile of Ddit3 motif

Sorted Z-values of Ddit3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr14_-_66868572 3.49 ENSMUST00000022629.8
dihydropyrimidinase-like 2
chr5_+_137288273 3.31 ENSMUST00000024099.4
ENSMUST00000085934.3
acetylcholinesterase
chr11_-_5152218 3.28 ENSMUST00000163299.1
ENSMUST00000062821.6
EMI domain containing 1
chr2_+_119351222 3.17 ENSMUST00000028780.3
ChaC, cation transport regulator 1
chr7_+_121083322 2.95 ENSMUST00000047025.8
ENSMUST00000170106.1
otoancorin
chr15_-_32244632 2.72 ENSMUST00000181536.1
RIKEN cDNA 0610007N19
chrX_+_52791179 2.44 ENSMUST00000101588.1
coiled-coil domain containing 160
chr2_-_152344009 2.34 ENSMUST00000040312.6
tribbles homolog 3 (Drosophila)
chr10_+_5639210 2.19 ENSMUST00000019906.4
vasoactive intestinal polypeptide
chr5_-_113081579 2.15 ENSMUST00000131708.1
ENSMUST00000117143.1
ENSMUST00000119627.1
crystallin, beta B3
chr4_-_117133953 2.14 ENSMUST00000076859.5
polo-like kinase 3
chr6_+_45060036 2.13 ENSMUST00000114641.1
contactin associated protein-like 2
chr18_+_38993126 2.10 ENSMUST00000097593.2
Rho GTPase activating protein 26
chr7_-_79793788 2.09 ENSMUST00000032760.5
mesoderm posterior 1
chr14_+_66868850 2.07 ENSMUST00000100453.1
predicted gene 5464
chr10_+_112271123 2.00 ENSMUST00000092175.2
potassium voltage gated channel, Shaw-related subfamily, member 2
chr3_-_92083132 1.79 ENSMUST00000058150.6
loricrin
chr5_+_33721724 1.68 ENSMUST00000067150.7
ENSMUST00000169212.2
ENSMUST00000114411.2
ENSMUST00000164207.3
fibroblast growth factor receptor 3
chr14_+_65971164 1.56 ENSMUST00000144619.1
clusterin
chr11_+_110399115 1.53 ENSMUST00000020949.5
ENSMUST00000100260.1
mitogen-activated protein kinase kinase 6
chr11_+_60728398 1.52 ENSMUST00000018743.4
mitochondrial elongation factor 2
chr10_+_13501001 1.50 ENSMUST00000060212.6
ENSMUST00000121465.2
fucosidase, alpha-L- 2, plasma
chr1_-_127677923 1.45 ENSMUST00000160616.1
transmembrane protein 163
chr14_+_65970804 1.38 ENSMUST00000138191.1
clusterin
chr3_+_108186332 1.34 ENSMUST00000050909.6
ENSMUST00000106659.2
ENSMUST00000106656.1
ENSMUST00000106661.2
adhesion molecule with Ig like domain 1
chr5_+_137553517 1.31 ENSMUST00000136088.1
ENSMUST00000139395.1
ENSMUST00000136565.1
ENSMUST00000149292.1
ENSMUST00000125489.1
actin-like 6B
chr17_+_37270214 1.29 ENSMUST00000038580.6
histocompatibility 2, M region locus 3
chr14_+_65971049 1.26 ENSMUST00000128539.1
clusterin
chr1_-_126492900 1.23 ENSMUST00000161954.1
NCK-associated protein 5
chrX_+_94724569 1.22 ENSMUST00000101388.2
zinc finger, X-linked, duplicated B
chr5_-_53707532 1.17 ENSMUST00000031093.3
cholecystokinin A receptor
chr10_-_109823585 1.12 ENSMUST00000161582.1
neuron navigator 3
chr7_+_120982521 1.12 ENSMUST00000149535.1
ENSMUST00000138177.1
RIKEN cDNA 4933427G17 gene
chr16_+_36041184 1.10 ENSMUST00000042203.8
WD repeat domain 5B
chr15_-_83510793 1.06 ENSMUST00000154401.1
tubulin tyrosine ligase-like 1
chr1_+_174501796 1.05 ENSMUST00000030039.7
formin 2
chr14_+_60732906 1.05 ENSMUST00000162945.1
spermatogenesis associated 13
chr18_-_37644185 1.02 ENSMUST00000066272.4
TAF7 RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr2_-_130839683 1.00 ENSMUST00000119422.1
RIKEN cDNA 4930402H24 gene
chr8_-_22476809 0.99 ENSMUST00000163774.1
ENSMUST00000033935.8
small integral membrane protein 19
chr15_-_83510861 0.99 ENSMUST00000109479.1
ENSMUST00000109480.1
ENSMUST00000016897.4
tubulin tyrosine ligase-like 1
chr18_+_37307445 0.96 ENSMUST00000056712.2
protocadherin beta 4
chr12_+_10390756 0.95 ENSMUST00000020947.5
retinol dehydrogenase 14 (all-trans and 9-cis)
chr6_-_138422898 0.94 ENSMUST00000161450.1
ENSMUST00000163024.1
ENSMUST00000162185.1
LIM domain only 3
chr7_-_46715676 0.92 ENSMUST00000006956.7
serum amyloid A 3
chr15_-_59082026 0.91 ENSMUST00000080371.6
metastasis suppressor 1
chr3_-_108200807 0.91 ENSMUST00000106655.1
ENSMUST00000065664.6
cytochrome b-561 domain containing 1
chrX_-_57338598 0.90 ENSMUST00000033468.4
ENSMUST00000114736.1
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr6_+_88724667 0.87 ENSMUST00000163271.1
monoglyceride lipase
chr16_+_24721842 0.87 ENSMUST00000115314.2
LIM domain containing preferred translocation partner in lipoma
chr11_-_96075655 0.84 ENSMUST00000090541.5
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit c1 (subunit 9)
chr3_+_90537306 0.84 ENSMUST00000107335.1
S100 calcium binding protein A16
chr3_-_58525867 0.84 ENSMUST00000029385.7
stress-associated endoplasmic reticulum protein 1
chr1_-_126492683 0.83 ENSMUST00000162877.1
NCK-associated protein 5
chr10_+_79996479 0.83 ENSMUST00000132517.1
ATP-binding cassette, sub-family A (ABC1), member 7
chr7_+_120982496 0.81 ENSMUST00000033166.3
RIKEN cDNA 4933427G17 gene
chr6_-_115592571 0.81 ENSMUST00000112957.1
RIKEN cDNA 2510049J12 gene
chr8_+_12915879 0.81 ENSMUST00000110876.2
ENSMUST00000110879.2
mcf.2 transforming sequence-like
chr5_-_43235352 0.77 ENSMUST00000140650.2
predicted gene 7854
chr2_-_32961592 0.77 ENSMUST00000133832.1
ENSMUST00000124492.1
ENSMUST00000145578.1
ENSMUST00000127321.1
ENSMUST00000113200.1
leucine rich repeat and sterile alpha motif containing 1
chr8_+_106603351 0.73 ENSMUST00000000312.5
ENSMUST00000167688.1
cadherin 1
chrX_+_103422010 0.72 ENSMUST00000182089.1
predicted gene, 26992
chr2_-_120850598 0.71 ENSMUST00000028740.4
tau tubulin kinase 2
chr12_-_87102350 0.71 ENSMUST00000110176.1
neuroglobin
chr11_-_96075581 0.70 ENSMUST00000107686.1
ENSMUST00000107684.1
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit c1 (subunit 9)
chr13_+_42680565 0.70 ENSMUST00000128646.1
phosphatase and actin regulator 1
chr18_+_37421418 0.66 ENSMUST00000053073.4
protocadherin beta 11
chr3_+_90537242 0.65 ENSMUST00000098911.3
S100 calcium binding protein A16
chr13_+_45965211 0.65 ENSMUST00000038032.3
RIKEN cDNA 5033430I15 gene
chr7_+_64287665 0.65 ENSMUST00000032736.4
myotubularin related protein 10
chr9_-_20644726 0.65 ENSMUST00000148631.1
ENSMUST00000131128.1
ENSMUST00000151861.1
ENSMUST00000131343.1
ENSMUST00000086458.3
F-box and leucine-rich repeat protein 12
chr13_-_113100971 0.64 ENSMUST00000023897.5
granzyme A
chr6_+_88724828 0.64 ENSMUST00000089449.2
monoglyceride lipase
chr5_-_36695969 0.63 ENSMUST00000031091.9
ENSMUST00000140063.1
DNA segment, Chr 5, ERATO Doi 579, expressed
chr3_-_108200415 0.62 ENSMUST00000106654.1
cytochrome b-561 domain containing 1
chr6_+_115675983 0.62 ENSMUST00000068960.9
RIKEN cDNA D830050J10 gene
chr8_-_64693027 0.61 ENSMUST00000048967.7
carboxypeptidase E
chr3_-_83049797 0.61 ENSMUST00000048246.3
fibrinogen beta chain
chr7_+_28437447 0.60 ENSMUST00000108292.2
ENSMUST00000108289.1
glia maturation factor, gamma
chr7_-_120982260 0.59 ENSMUST00000033169.8
cerebellar degeneration-related 2
chr18_+_37333853 0.57 ENSMUST00000061717.2
protocadherin beta 6
chr1_+_188263034 0.57 ENSMUST00000060479.7
Usher syndrome 2A (autosomal recessive, mild)
chr1_-_165460430 0.57 ENSMUST00000027856.7
DDB1 and CUL4 associated factor 6
chr3_-_97297778 0.57 ENSMUST00000181368.1
predicted gene, 17608
chr9_-_44799179 0.56 ENSMUST00000114705.1
ENSMUST00000002100.7
transmembrane protein 25
chr2_+_16356744 0.56 ENSMUST00000114703.3
plexin domain containing 2
chr1_-_5019342 0.55 ENSMUST00000002533.8
regulator of G-protein signaling 20
chr2_+_181837854 0.55 ENSMUST00000029116.7
ENSMUST00000108754.1
protein-L-isoaspartate (D-aspartate) O-methyltransferase domain containing 2
chr6_+_21215472 0.54 ENSMUST00000081542.5
potassium voltage-gated channel, Shal-related family, member 2
chr8_+_45627946 0.51 ENSMUST00000145458.1
sorbin and SH3 domain containing 2
chr7_-_42727017 0.50 ENSMUST00000166837.1
predicted gene 17067
chr15_-_93595877 0.49 ENSMUST00000048982.4
prickle homolog 1 (Drosophila)
chr8_-_67818284 0.47 ENSMUST00000120071.1
pleckstrin and Sec7 domain containing 3
chr4_+_115057683 0.47 ENSMUST00000161601.1
T cell acute lymphocytic leukemia 1
chr11_+_71750980 0.46 ENSMUST00000108511.1
WSC domain containing 1
chr5_-_120749848 0.46 ENSMUST00000053909.6
ENSMUST00000081491.6
2'-5' oligoadenylate synthetase 2
chr7_-_75309262 0.44 ENSMUST00000165175.1
synaptic vesicle glycoprotein 2 b
chr9_-_95845215 0.42 ENSMUST00000093800.2
plastin 1 (I-isoform)
chr7_-_126082406 0.42 ENSMUST00000073935.5
GSG1-like
chr9_+_20644851 0.42 ENSMUST00000161882.1
ubiquitin-like 5
chr2_-_91195035 0.42 ENSMUST00000111356.1
nuclear receptor subfamily 1, group H, member 3
chr9_+_57236556 0.42 ENSMUST00000093837.3
taste receptor cell gene 1
chr14_+_59201209 0.41 ENSMUST00000173547.1
ENSMUST00000043227.6
ENSMUST00000022551.7
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 1
chr11_+_51763682 0.41 ENSMUST00000020653.5
SAR1 gene homolog B (S. cerevisiae)
chr18_+_37355271 0.41 ENSMUST00000051163.1
protocadherin beta 8
chr8_+_94386486 0.40 ENSMUST00000034220.7
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
chr19_+_47865543 0.39 ENSMUST00000120645.1
glutathione S-transferase omega 2
chr2_-_91195097 0.38 ENSMUST00000002177.2
ENSMUST00000111354.1
nuclear receptor subfamily 1, group H, member 3
chrX_-_162565514 0.38 ENSMUST00000154424.1
RALBP1 associated Eps domain containing protein 2
chr4_+_103619580 0.37 ENSMUST00000106827.1
disabled 1
chr8_+_94386438 0.37 ENSMUST00000161576.1
homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1
chr15_+_32244801 0.36 ENSMUST00000067458.6
sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A
chr2_-_172454742 0.36 ENSMUST00000161334.1
glucosaminyl (N-acetyl) transferase family member 7
chr16_+_4939099 0.36 ENSMUST00000050881.8
nudix (nucleoside diphosphate linked moiety X)-type motif 16-like 1
chr8_-_47533439 0.36 ENSMUST00000039061.8
trafficking protein particle complex 11
chr12_-_69681795 0.36 ENSMUST00000183277.1
ENSMUST00000035773.7
son of sevenless homolog 2 (Drosophila)
chr2_-_91194767 0.36 ENSMUST00000111355.1
nuclear receptor subfamily 1, group H, member 3
chr3_-_151835967 0.35 ENSMUST00000106126.1
prostaglandin F receptor
chr5_-_74531619 0.34 ENSMUST00000113542.2
ENSMUST00000072857.6
ENSMUST00000121330.1
ENSMUST00000151474.1
Sec1 family domain containing 2
chr2_-_131328982 0.32 ENSMUST00000110194.1
ring finger protein 24
chr11_-_116199040 0.32 ENSMUST00000066587.5
acyl-Coenzyme A oxidase 1, palmitoyl
chr3_-_153906138 0.32 ENSMUST00000005630.4
mutS homolog 4 (E. coli)
chr12_+_105604091 0.31 ENSMUST00000041229.4
bradykinin receptor, beta 1
chr6_-_34955903 0.31 ENSMUST00000147169.1
RIKEN cDNA 2010107G12 gene
chr4_-_101844023 0.31 ENSMUST00000106919.1
RIKEN cDNA B020004J07 gene
chr17_-_46890405 0.30 ENSMUST00000086675.3
RIKEN cDNA A330017A19 gene
chr9_+_20644792 0.30 ENSMUST00000162303.1
ENSMUST00000161486.1
ubiquitin-like 5
chr7_+_24112314 0.30 ENSMUST00000120006.1
ENSMUST00000005413.3
zinc finger protein 112
chr8_+_25720054 0.29 ENSMUST00000068916.8
ENSMUST00000139836.1
phosphatidic acid phosphatase type 2 domain containing 1B
chr7_+_107370728 0.29 ENSMUST00000137663.1
ENSMUST00000073459.5
synaptotagmin IX
chr14_-_21052120 0.28 ENSMUST00000130370.1
ENSMUST00000022371.3
adaptor-related protein complex 3, mu 1 subunit
chr2_+_23069210 0.28 ENSMUST00000155602.1
acyl-Coenzyme A binding domain containing 5
chr14_-_103843685 0.28 ENSMUST00000172237.1
endothelin receptor type B
chr8_+_45627709 0.27 ENSMUST00000134321.1
ENSMUST00000135336.1
sorbin and SH3 domain containing 2
chr10_+_127195240 0.27 ENSMUST00000181578.1
RIKEN cDNA F420014N23 gene
chr2_+_90904740 0.27 ENSMUST00000111464.1
ENSMUST00000090682.3
kelch repeat and BTB (POZ) domain containing 4
chr16_-_4939579 0.27 ENSMUST00000181498.1
predicted gene, 16861
chr7_-_126776818 0.26 ENSMUST00000068836.4
predicted gene 9967
chr14_-_52020698 0.26 ENSMUST00000067549.7
zinc finger protein 219
chr1_-_58586191 0.25 ENSMUST00000038372.7
ENSMUST00000097724.3
ENSMUST00000161000.1
ENSMUST00000161600.1
family with sequence similarity 126, member B
chr3_-_49757257 0.25 ENSMUST00000035931.7
protocadherin 18
chr6_-_114969986 0.22 ENSMUST00000139640.1
vestigial like 4 (Drosophila)
chr17_+_34417347 0.22 ENSMUST00000142317.1
cDNA sequence BC051142
chr1_-_195131536 0.21 ENSMUST00000075451.6
complement component (3b/4b) receptor 1-like
chr13_-_104816908 0.20 ENSMUST00000022228.6
CWC27 spliceosome-associated protein homolog (S. cerevisiae)
chr2_-_45117349 0.19 ENSMUST00000176438.2
zinc finger E-box binding homeobox 2
chr7_+_30776394 0.18 ENSMUST00000041703.7
dermokine
chr9_-_121495678 0.18 ENSMUST00000035120.4
cholecystokinin
chr17_+_34898463 0.17 ENSMUST00000114033.2
ENSMUST00000078061.6
euchromatic histone lysine N-methyltransferase 2
chr8_+_123443288 0.17 ENSMUST00000108830.1
differentially expressed in FDCP 8
chr8_-_99416397 0.16 ENSMUST00000155527.1
ENSMUST00000142129.1
ENSMUST00000093249.4
ENSMUST00000142475.2
ENSMUST00000128860.1
cadherin 8
chr4_-_117765550 0.16 ENSMUST00000062747.5
Kruppel-like factor 17
chr11_-_59163696 0.15 ENSMUST00000137433.1
ENSMUST00000054523.5
IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae)
chr12_+_78691516 0.15 ENSMUST00000077968.4
family with sequence similarity 71, member D
chr6_+_71322775 0.15 ENSMUST00000065248.7
CD8 antigen, beta chain 1
chr11_+_110997487 0.15 ENSMUST00000106635.1
potassium inwardly-rectifying channel, subfamily J, member 16
chr17_-_35132050 0.14 ENSMUST00000025249.6
apolipoprotein M
chr16_-_87432597 0.12 ENSMUST00000039449.7
listerin E3 ubiquitin protein ligase 1
chr6_+_120093348 0.12 ENSMUST00000112711.2
ninjurin 2
chr11_+_54303798 0.12 ENSMUST00000093106.5
acyl-CoA synthetase long-chain family member 6
chr8_+_92961027 0.11 ENSMUST00000072939.6
solute carrier family 6 (neurotransmitter transporter, noradrenalin), member 2
chr5_-_31526693 0.11 ENSMUST00000118874.1
ENSMUST00000117642.1
ENSMUST00000065388.4
suppressor of Ty 7-like
chr14_+_20348159 0.10 ENSMUST00000090503.4
ENSMUST00000090499.5
ENSMUST00000037698.5
ENSMUST00000051915.6
family with sequence similarity 149, member B
chr9_-_105521147 0.09 ENSMUST00000176770.1
ENSMUST00000085133.6
ATPase, Ca++-sequestering
chr6_+_86078070 0.09 ENSMUST00000032069.5
adducin 2 (beta)
chr16_+_78301458 0.08 ENSMUST00000023572.7
coxsackie virus and adenovirus receptor
chr6_+_48895243 0.08 ENSMUST00000031835.7
amine oxidase, copper-containing 1
chr11_+_116198853 0.07 ENSMUST00000021130.6
TEN1 telomerase capping complex subunit
chr17_-_15564322 0.06 ENSMUST00000147532.1
PR domain containing 9
chr14_-_47568427 0.06 ENSMUST00000042988.6
autophagy related 14
chr11_-_120643643 0.06 ENSMUST00000141254.1
ENSMUST00000170556.1
ENSMUST00000151876.1
ENSMUST00000026133.8
ENSMUST00000139706.1
pyrroline-5-carboxylate reductase 1
chr11_+_101070012 0.06 ENSMUST00000001802.9
alpha-N-acetylglucosaminidase (Sanfilippo disease IIIB)
chr14_+_63606491 0.05 ENSMUST00000119973.2
X Kell blood group precursor related family member 6 homolog
chr15_-_59374149 0.05 ENSMUST00000022976.4
RIKEN cDNA E430025E21 gene
chrX_-_60147643 0.04 ENSMUST00000033478.4
ENSMUST00000101531.3
mcf.2 transforming sequence
chr2_+_137663424 0.04 ENSMUST00000134833.1
predicted gene 14064
chr11_+_98809787 0.03 ENSMUST00000169695.1
cancer susceptibility candidate 3
chr19_-_43912392 0.02 ENSMUST00000026209.4
dynamin binding protein
chr5_-_43981757 0.02 ENSMUST00000061299.7
fibroblast growth factor binding protein 1
chr9_+_108080436 0.02 ENSMUST00000035211.7
ENSMUST00000162886.1
macrophage stimulating 1 (hepatocyte growth factor-like)
chr8_+_123442969 0.02 ENSMUST00000093049.3
ENSMUST00000065534.3
ENSMUST00000001522.3
ENSMUST00000124741.1
ENSMUST00000108832.1
ENSMUST00000132063.1
ENSMUST00000128424.1
differentially expressed in FDCP 8
chr7_-_126377401 0.01 ENSMUST00000119846.1
ENSMUST00000119754.1
ENSMUST00000032994.8
spinster homolog 1
chr5_-_131538687 0.01 ENSMUST00000161374.1
autism susceptibility candidate 2
chr13_-_113618549 0.01 ENSMUST00000109241.3
sorting nexin 18
chr5_+_31526989 0.01 ENSMUST00000114533.2
ENSMUST00000117262.1
ENSMUST00000117319.1
solute carrier family 4 (anion exchanger), member 1, adaptor protein
chr3_-_127408986 0.00 ENSMUST00000182588.1
ENSMUST00000182959.1
ENSMUST00000182452.1
ankyrin 2, brain
chr10_+_18055711 0.00 ENSMUST00000154718.1
ENSMUST00000126390.1
ENSMUST00000164556.1
ENSMUST00000150029.1
RalBP1 associated Eps domain containing protein
chr2_-_164071089 0.00 ENSMUST00000018466.3
translocase of outer mitochondrial membrane 34
chr13_+_24614608 0.00 ENSMUST00000091694.3
family with sequence similarity 65, member B

Network of associatons between targets according to the STRING database.

First level regulatory network of Ddit3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 4.2 GO:1902998 regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.7 2.1 GO:0090381 Notch signaling pathway involved in heart induction(GO:0003137) regulation of Notch signaling pathway involved in heart induction(GO:0035480) positive regulation of Notch signaling pathway involved in heart induction(GO:0035481) regulation of heart induction(GO:0090381) positive regulation of heart induction(GO:1901321)
0.7 3.3 GO:0008291 acetylcholine metabolic process(GO:0008291) acetate ester metabolic process(GO:1900619)
0.6 1.7 GO:0061144 alveolar secondary septum development(GO:0061144)
0.4 2.2 GO:0010578 regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579)
0.4 2.1 GO:0045163 clustering of voltage-gated potassium channels(GO:0045163)
0.4 1.2 GO:0090274 reduction of food intake in response to dietary excess(GO:0002023) positive regulation of somatostatin secretion(GO:0090274)
0.4 1.2 GO:0090341 negative regulation of secretion of lysosomal enzymes(GO:0090341)
0.4 1.1 GO:0016344 meiotic chromosome movement towards spindle pole(GO:0016344) formin-nucleated actin cable assembly(GO:0070649)
0.3 1.3 GO:0002767 immune response-inhibiting cell surface receptor signaling pathway(GO:0002767)
0.3 0.9 GO:0034334 adherens junction maintenance(GO:0034334)
0.3 3.2 GO:0006751 glutathione catabolic process(GO:0006751)
0.3 0.8 GO:1901074 regulation of engulfment of apoptotic cell(GO:1901074)
0.2 2.1 GO:0090166 Golgi disassembly(GO:0090166) regulation of chaperone-mediated autophagy(GO:1904714)
0.2 2.1 GO:0018095 protein polyglutamylation(GO:0018095)
0.2 1.5 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.2 0.6 GO:0071846 actin filament debranching(GO:0071846)
0.2 0.8 GO:0070086 ubiquitin-dependent endocytosis(GO:0070086)
0.2 1.5 GO:0006004 fucose metabolic process(GO:0006004)
0.2 0.7 GO:0015671 oxygen transport(GO:0015671)
0.2 2.9 GO:0014049 positive regulation of glutamate secretion(GO:0014049)
0.2 2.0 GO:1903818 cellular response to nitric oxide(GO:0071732) positive regulation of voltage-gated potassium channel activity(GO:1903818)
0.2 0.6 GO:0030070 insulin processing(GO:0030070)
0.2 0.6 GO:0043152 induction of bacterial agglutination(GO:0043152)
0.1 0.7 GO:0060066 oviduct development(GO:0060066)
0.1 0.6 GO:0048496 maintenance of organ identity(GO:0048496)
0.1 1.5 GO:0032464 positive regulation of protein homooligomerization(GO:0032464)
0.1 2.3 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.1 0.8 GO:1903071 positive regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903071)
0.1 1.5 GO:0032308 positive regulation of prostaglandin secretion(GO:0032308)
0.1 0.4 GO:0021577 hindbrain structural organization(GO:0021577) cerebellum structural organization(GO:0021589) lateral motor column neuron migration(GO:0097477)
0.1 0.8 GO:0060124 positive regulation of growth hormone secretion(GO:0060124)
0.1 0.3 GO:0071799 response to prostaglandin D(GO:0071798) cellular response to prostaglandin D stimulus(GO:0071799)
0.1 0.4 GO:1902896 terminal web assembly(GO:1902896)
0.1 1.8 GO:0031424 keratinization(GO:0031424)
0.1 0.5 GO:0051890 regulation of cardioblast differentiation(GO:0051890)
0.1 0.3 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.1 0.6 GO:0032074 negative regulation of nuclease activity(GO:0032074)
0.1 1.7 GO:0007413 axonal fasciculation(GO:0007413)
0.1 0.5 GO:0018377 protein myristoylation(GO:0018377)
0.1 0.4 GO:0009407 toxin catabolic process(GO:0009407) secondary metabolite catabolic process(GO:0090487)
0.1 0.1 GO:0010845 positive regulation of reciprocal meiotic recombination(GO:0010845)
0.1 0.7 GO:1990403 embryonic brain development(GO:1990403)
0.1 0.3 GO:0007494 midgut development(GO:0007494) vein smooth muscle contraction(GO:0014826)
0.1 0.4 GO:2001032 regulation of double-strand break repair via nonhomologous end joining(GO:2001032)
0.0 1.5 GO:0015991 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986) ATP hydrolysis coupled proton transport(GO:0015991)
0.0 0.1 GO:0034443 regulation of lipoprotein oxidation(GO:0034442) negative regulation of lipoprotein oxidation(GO:0034443)
0.0 0.9 GO:0035634 response to stilbenoid(GO:0035634)
0.0 0.2 GO:1903575 cornified envelope assembly(GO:1903575)
0.0 0.9 GO:0042572 retinol metabolic process(GO:0042572)
0.0 0.4 GO:2000973 regulation of pro-B cell differentiation(GO:2000973)
0.0 0.1 GO:0060217 hemangioblast cell differentiation(GO:0060217)
0.0 0.3 GO:0030242 pexophagy(GO:0030242)
0.0 1.0 GO:0035067 negative regulation of histone acetylation(GO:0035067)
0.0 0.4 GO:0061635 regulation of protein complex stability(GO:0061635)
0.0 3.5 GO:0019226 transmission of nerve impulse(GO:0019226)
0.0 0.2 GO:0061373 mammillary body development(GO:0021767) mammillary axonal complex development(GO:0061373) positive regulation of lens fiber cell differentiation(GO:1902748)
0.0 0.3 GO:0051026 chiasma assembly(GO:0051026)
0.0 0.2 GO:2000258 negative regulation of complement activation(GO:0045916) negative regulation of protein activation cascade(GO:2000258)
0.0 1.9 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.1 GO:0030026 cellular manganese ion homeostasis(GO:0030026) Golgi calcium ion homeostasis(GO:0032468) manganese ion homeostasis(GO:0055071)
0.0 0.8 GO:0035025 positive regulation of Rho protein signal transduction(GO:0035025)
0.0 0.1 GO:0010747 positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747)
0.0 0.4 GO:2000311 regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity(GO:2000311)
0.0 0.2 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.1 GO:0060054 positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.0 0.1 GO:0016240 autophagosome docking(GO:0016240)
0.0 2.2 GO:0007601 visual perception(GO:0007601)
0.0 2.3 GO:0007416 synapse assembly(GO:0007416)
0.0 0.3 GO:0099514 anterograde synaptic vesicle transport(GO:0048490) synaptic vesicle cytoskeletal transport(GO:0099514) synaptic vesicle transport along microtubule(GO:0099517)
0.0 0.3 GO:0045956 positive regulation of calcium ion-dependent exocytosis(GO:0045956)
0.0 0.1 GO:0015874 norepinephrine transport(GO:0015874)
0.0 1.3 GO:0051592 response to calcium ion(GO:0051592)
0.0 0.3 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.0 0.5 GO:0003298 physiological muscle hypertrophy(GO:0003298) physiological cardiac muscle hypertrophy(GO:0003301) cell growth involved in cardiac muscle cell development(GO:0061049)
0.0 0.8 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.0 0.1 GO:0071280 cellular response to copper ion(GO:0071280)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 4.2 GO:0097418 neurofibrillary tangle(GO:0097418)
0.3 3.5 GO:0043083 synaptic cleft(GO:0043083)
0.2 0.8 GO:1990037 Lewy body core(GO:1990037)
0.1 1.8 GO:0001533 cornified envelope(GO:0001533)
0.1 0.6 GO:1990696 USH2 complex(GO:1990696)
0.1 4.1 GO:0030673 axolemma(GO:0030673)
0.1 1.5 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1 0.3 GO:0005713 recombination nodule(GO:0005713)
0.1 1.0 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.1 0.6 GO:0005577 fibrinogen complex(GO:0005577)
0.1 1.3 GO:0016514 SWI/SNF complex(GO:0016514)
0.1 1.4 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.1 0.9 GO:0031045 dense core granule(GO:0031045)
0.1 0.7 GO:0016600 flotillin complex(GO:0016600) lateral loop(GO:0043219)
0.1 0.4 GO:1990357 terminal web(GO:1990357)
0.1 1.3 GO:0042611 MHC protein complex(GO:0042611)
0.0 1.9 GO:0032809 neuronal cell body membrane(GO:0032809)
0.0 1.1 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 5.3 GO:0043195 terminal bouton(GO:0043195)
0.0 0.9 GO:0043196 varicosity(GO:0043196)
0.0 0.1 GO:0033193 Lsd1/2 complex(GO:0033193)
0.0 0.4 GO:0032279 asymmetric synapse(GO:0032279)
0.0 3.3 GO:0005581 collagen trimer(GO:0005581)
0.0 0.1 GO:0097629 extrinsic component of omegasome membrane(GO:0097629)
0.0 0.8 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.3 GO:1904115 axon cytoplasm(GO:1904115)
0.0 2.1 GO:0005795 Golgi stack(GO:0005795)
0.0 0.4 GO:0030008 TRAPP complex(GO:0030008)
0.0 3.8 GO:0005802 trans-Golgi network(GO:0005802)
0.0 0.7 GO:0035869 ciliary transition zone(GO:0035869)
0.0 2.6 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.6 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 1.3 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.8 GO:0005881 cytoplasmic microtubule(GO:0005881)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 3.3 GO:0004104 cholinesterase activity(GO:0004104)
0.6 3.2 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.6 1.8 GO:0030280 structural constituent of epidermis(GO:0030280)
0.5 2.1 GO:0070740 tubulin-glutamic acid ligase activity(GO:0070740)
0.5 1.5 GO:0004560 alpha-L-fucosidase activity(GO:0004560) fucosidase activity(GO:0015928)
0.3 0.8 GO:0090556 apolipoprotein receptor activity(GO:0030226) apolipoprotein A-I receptor activity(GO:0034188) phosphatidylserine-translocating ATPase activity(GO:0090556)
0.3 1.0 GO:0061628 H3K27me3 modified histone binding(GO:0061628)
0.2 1.2 GO:0032810 sterol response element binding(GO:0032810)
0.2 1.7 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.2 0.7 GO:0005344 oxygen transporter activity(GO:0005344)
0.2 4.2 GO:0051787 misfolded protein binding(GO:0051787)
0.2 2.2 GO:0005212 structural constituent of eye lens(GO:0005212)
0.1 0.4 GO:0016672 oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor(GO:0016672) oxidoreductase activity, acting on phosphorus or arsenic in donors(GO:0030613) oxidoreductase activity, acting on phosphorus or arsenic in donors, disulfide as acceptor(GO:0030614) glutathione dehydrogenase (ascorbate) activity(GO:0045174) methylarsonate reductase activity(GO:0050610)
0.1 2.3 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.1 0.4 GO:0035373 chondroitin sulfate proteoglycan binding(GO:0035373)
0.1 0.9 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.1 0.6 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.1 0.5 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.1 0.3 GO:0004947 bradykinin receptor activity(GO:0004947)
0.1 1.5 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 2.0 GO:0005251 delayed rectifier potassium channel activity(GO:0005251)
0.1 0.3 GO:0004962 endothelin receptor activity(GO:0004962)
0.1 1.5 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1 1.5 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.1 0.6 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.1 0.9 GO:0008106 alcohol dehydrogenase (NADP+) activity(GO:0008106)
0.1 0.3 GO:0016401 palmitoyl-CoA oxidase activity(GO:0016401)
0.1 0.7 GO:0031386 protein tag(GO:0031386)
0.0 0.5 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.0 0.7 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.8 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 1.3 GO:0042605 peptide antigen binding(GO:0042605)
0.0 0.1 GO:0005333 norepinephrine transmembrane transporter activity(GO:0005333)
0.0 0.3 GO:0004955 prostaglandin receptor activity(GO:0004955)
0.0 0.3 GO:0030983 mismatched DNA binding(GO:0030983)
0.0 1.0 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 2.4 GO:0005179 hormone activity(GO:0005179)
0.0 0.9 GO:0003785 actin monomer binding(GO:0003785)
0.0 2.2 GO:0002039 p53 binding(GO:0002039)
0.0 0.4 GO:0050072 m7G(5')pppN diphosphatase activity(GO:0050072)
0.0 0.1 GO:0015410 manganese-transporting ATPase activity(GO:0015410)
0.0 0.7 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.1 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.0 2.2 GO:0035326 enhancer binding(GO:0035326)
0.0 1.3 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 1.2 GO:0008528 G-protein coupled peptide receptor activity(GO:0008528)
0.0 0.2 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.1 GO:0008131 primary amine oxidase activity(GO:0008131)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.5 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 2.8 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 3.3 PID ATF2 PATHWAY ATF-2 transcription factor network
0.0 3.6 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.7 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 2.1 PID FAK PATHWAY Signaling events mediated by focal adhesion kinase
0.0 1.7 PID FGF PATHWAY FGF signaling pathway
0.0 1.2 PID RXR VDR PATHWAY RXR and RAR heterodimerization with other nuclear receptor
0.0 0.9 ST G ALPHA I PATHWAY G alpha i Pathway
0.0 4.5 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 0.4 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.0 0.9 PID ARF6 TRAFFICKING PATHWAY Arf6 trafficking events
0.0 1.4 PID P73PATHWAY p73 transcription factor network
0.0 0.9 PID HEDGEHOG GLI PATHWAY Hedgehog signaling events mediated by Gli proteins
0.0 0.4 PID REELIN PATHWAY Reelin signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 3.5 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.2 2.3 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.1 1.7 REACTOME SIGNALING BY FGFR3 MUTANTS Genes involved in Signaling by FGFR3 mutants
0.1 3.3 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.1 1.5 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.1 1.5 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.1 1.5 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.1 2.5 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.7 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 4.8 REACTOME RESPONSE TO ELEVATED PLATELET CYTOSOLIC CA2 Genes involved in Response to elevated platelet cytosolic Ca2+
0.0 2.2 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors
0.0 0.8 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.9 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.3 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 0.8 REACTOME ACTIVATION OF GENES BY ATF4 Genes involved in Activation of Genes by ATF4
0.0 0.6 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.0 0.4 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.4 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.6 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 0.3 REACTOME ALPHA LINOLENIC ACID ALA METABOLISM Genes involved in alpha-linolenic acid (ALA) metabolism
0.0 0.4 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.8 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 1.9 REACTOME PEPTIDE LIGAND BINDING RECEPTORS Genes involved in Peptide ligand-binding receptors
0.0 2.1 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases