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2D miR_HR1_12

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Results for Hcfc1_Six5_Smarcc2_Zfp143

Z-value: 6.42

Motif logo

Transcription factors associated with Hcfc1_Six5_Smarcc2_Zfp143

Gene Symbol Gene ID Gene Info
ENSMUSG00000031386.8 host cell factor C1
ENSMUSG00000040841.5 sine oculis-related homeobox 5
ENSMUSG00000025369.8 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 2
ENSMUSG00000061079.7 zinc finger protein 143

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Hcfc1mm10_v2_chrX_-_73966329_739663760.922.8e-05Click!
Zfp143mm10_v2_chr7_+_110061702_1100617320.863.1e-04Click!
Six5mm10_v2_chr7_+_19094594_19094633-0.792.2e-03Click!
Smarcc2mm10_v2_chr10_+_128459236_1284592480.594.2e-02Click!

Activity profile of Hcfc1_Six5_Smarcc2_Zfp143 motif

Sorted Z-values of Hcfc1_Six5_Smarcc2_Zfp143 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr2_+_118598209 20.95 ENSMUST00000038341.7
budding uninhibited by benzimidazoles 1 homolog, beta (S. cerevisiae)
chr6_+_124829540 16.49 ENSMUST00000150120.1
cell division cycle associated 3
chr2_+_152847961 14.72 ENSMUST00000164120.1
ENSMUST00000178997.1
ENSMUST00000109816.1
TPX2, microtubule-associated protein homolog (Xenopus laevis)
chr5_+_33658123 13.86 ENSMUST00000074849.6
ENSMUST00000079534.4
transforming, acidic coiled-coil containing protein 3
chr1_+_178187721 13.73 ENSMUST00000159284.1
desumoylating isopeptidase 2
chr2_+_152847993 13.66 ENSMUST00000028969.8
TPX2, microtubule-associated protein homolog (Xenopus laevis)
chr11_+_117849223 12.55 ENSMUST00000081387.4
baculoviral IAP repeat-containing 5
chr11_+_117849286 11.84 ENSMUST00000093906.4
baculoviral IAP repeat-containing 5
chr6_+_124829582 11.32 ENSMUST00000024270.7
cell division cycle associated 3
chr11_-_101551837 11.22 ENSMUST00000017290.4
breast cancer 1
chr19_-_10203880 10.18 ENSMUST00000142241.1
ENSMUST00000116542.2
ENSMUST00000025651.5
ENSMUST00000156291.1
flap structure specific endonuclease 1
chr7_+_13278778 10.12 ENSMUST00000098814.4
ENSMUST00000146998.1
ENSMUST00000185145.1
ligase I, DNA, ATP-dependent
chr13_-_35906324 10.09 ENSMUST00000174230.1
ENSMUST00000171686.2
ribonuclease P 40 subunit
chr8_+_71464910 9.62 ENSMUST00000048914.6
mitochondrial ribosomal protein L34
chr4_-_124936852 9.60 ENSMUST00000030690.5
ENSMUST00000084296.3
cell division cycle associated 8
chr14_-_65833963 9.15 ENSMUST00000022613.9
establishment of cohesion 1 homolog 2 (S. cerevisiae)
chr15_+_102296256 9.09 ENSMUST00000064924.4
extra spindle poles-like 1 (S. cerevisiae)
chr4_-_117182623 9.03 ENSMUST00000065896.2
kinesin family member 2C
chr4_+_107367757 8.94 ENSMUST00000139560.1
NDC1 transmembrane nucleoporin
chr19_+_5024006 8.79 ENSMUST00000025826.5
solute carrier family 29 (nucleoside transporters), member 2
chr13_-_54590047 8.66 ENSMUST00000148222.1
ENSMUST00000026987.5
NOP16 nucleolar protein
chr9_+_26999668 8.52 ENSMUST00000039161.8
thymocyte nuclear protein 1
chr15_+_85859689 8.31 ENSMUST00000170629.1
G two S phase expressed protein 1
chr12_-_91384403 8.25 ENSMUST00000141429.1
centrosomal protein 128
chr15_-_53902472 8.16 ENSMUST00000078673.6
sterile alpha motif domain containing 12
chr9_+_107587711 8.13 ENSMUST00000010192.5
interferon-related developmental regulator 2
chr3_+_88081997 7.96 ENSMUST00000071812.5
IQ motif containing GTPase activating protein 3
chr19_-_9899450 7.95 ENSMUST00000025562.7
inner centromere protein
chr19_-_41802028 7.85 ENSMUST00000026150.8
ENSMUST00000177495.1
ENSMUST00000163265.1
Rho GTPase activating protein 19
chr4_-_41275091 7.82 ENSMUST00000030143.6
ENSMUST00000108068.1
ubiquitin-associated protein 2
chr4_+_156109971 7.81 ENSMUST00000072554.6
ENSMUST00000169550.1
ENSMUST00000105576.1
RIKEN cDNA 9430015G10 gene
chr15_+_78428564 7.71 ENSMUST00000166142.2
ENSMUST00000162517.1
ENSMUST00000089414.4
potassium channel tetramerisation domain containing 17
chr8_+_85492568 7.50 ENSMUST00000034136.5
glutamic pyruvate transaminase (alanine aminotransferase) 2
chrY_+_90784738 7.41 ENSMUST00000179483.1
erythroid differentiation regulator 1
chr13_+_41249841 7.14 ENSMUST00000165561.2
small integral membrane protein 13
chr5_+_30711564 7.07 ENSMUST00000114729.1
dihydropyrimidinase-like 5
chr10_-_128565827 6.99 ENSMUST00000131728.1
ENSMUST00000026425.6
proliferation-associated 2G4
chr19_+_36083696 6.93 ENSMUST00000025714.7
ribonuclease P/MRP 30 subunit
chr4_+_134468320 6.93 ENSMUST00000030636.4
ENSMUST00000127279.1
ENSMUST00000105867.1
stathmin 1
chr9_+_78109188 6.91 ENSMUST00000118869.1
ENSMUST00000125615.1
intestinal cell kinase
chr5_+_30711849 6.91 ENSMUST00000088081.4
ENSMUST00000101442.3
dihydropyrimidinase-like 5
chr9_+_106281061 6.81 ENSMUST00000072206.6
POC1 centriolar protein homolog A (Chlamydomonas)
chr10_+_77033260 6.70 ENSMUST00000136925.1
ENSMUST00000130703.1
solute carrier family 19 (folate transporter), member 1
chr17_-_35673517 6.59 ENSMUST00000162266.1
ENSMUST00000160734.1
ENSMUST00000159852.1
ENSMUST00000160039.1
general transcription factor II H, polypeptide 4
chr5_+_108132885 6.57 ENSMUST00000047677.7
coiled-coil domain containing 18
chr15_-_81729864 6.45 ENSMUST00000171115.1
ENSMUST00000170134.1
ENSMUST00000052374.5
RAN GTPase activating protein 1
chr5_+_21424934 6.45 ENSMUST00000056045.4
family with sequence similarity 185, member A
chr2_-_26021532 6.37 ENSMUST00000136750.1
ubiquitin associated domain containing 1
chr2_+_119112793 6.30 ENSMUST00000140939.1
ENSMUST00000028795.3
RAD51 homolog
chr1_+_175880775 6.28 ENSMUST00000039725.6
exonuclease 1
chr8_+_105860634 6.24 ENSMUST00000008594.7
nuclear transport factor 2
chr2_-_26021679 6.23 ENSMUST00000036509.7
ubiquitin associated domain containing 1
chr17_-_23673557 6.21 ENSMUST00000115489.1
THO complex 6 homolog (Drosophila)
chr10_+_40883819 6.19 ENSMUST00000105509.1
WAS protein family, member 1
chr5_+_110839973 6.19 ENSMUST00000066160.1
checkpoint kinase 2
chr4_+_126556935 6.08 ENSMUST00000048391.8
claspin
chr10_+_77033212 5.97 ENSMUST00000105410.3
solute carrier family 19 (folate transporter), member 1
chr11_+_16951371 5.95 ENSMUST00000109635.1
ENSMUST00000061327.1
F-box protein 48
chr2_+_129100995 5.93 ENSMUST00000103205.4
ENSMUST00000028874.7
polymerase (RNA) I polypeptide B
chr6_-_112696604 5.93 ENSMUST00000113182.1
ENSMUST00000113180.1
ENSMUST00000068487.5
ENSMUST00000077088.4
RAD18 homolog (S. cerevisiae)
chr10_-_80918212 5.89 ENSMUST00000057623.7
ENSMUST00000179022.1
lamin B2
chr19_+_46056539 5.87 ENSMUST00000111899.1
ENSMUST00000099392.3
ENSMUST00000062322.4
peroxisome proliferative activated receptor, gamma, coactivator-related 1
chr1_-_60098104 5.82 ENSMUST00000143342.1
WD repeat domain 12
chr17_-_23673825 5.77 ENSMUST00000115490.1
ENSMUST00000047436.4
ENSMUST00000138190.1
ENSMUST00000095579.4
THO complex 6 homolog (Drosophila)
chr1_-_20820213 5.77 ENSMUST00000053266.9
minichromosome maintenance deficient 3 (S. cerevisiae)
chr19_-_47050823 5.77 ENSMUST00000026032.5
polycomb group ring finger 6
chr14_-_99099701 5.75 ENSMUST00000042471.9
DIS3 mitotic control homolog (S. cerevisiae)
chr10_+_77033304 5.71 ENSMUST00000132984.1
solute carrier family 19 (folate transporter), member 1
chr10_-_81496329 5.62 ENSMUST00000020463.7
nicalin homolog (zebrafish)
chr7_+_29303958 5.60 ENSMUST00000049977.6
D4, zinc and double PHD fingers family 1
chr3_+_88532314 5.52 ENSMUST00000172699.1
mex3 homolog A (C. elegans)
chr18_-_77767752 5.46 ENSMUST00000048192.7
HAUS augmin-like complex, subunit 1
chr2_+_181680284 5.38 ENSMUST00000103042.3
transcription elongation factor A (SII), 2
chr2_+_173021902 5.38 ENSMUST00000029014.9
RNA binding motif protein 38
chr6_+_35177610 5.37 ENSMUST00000170234.1
nucleoporin 205
chr8_+_57488053 5.36 ENSMUST00000180690.1
RIKEN cDNA 2500002B13 gene
chr3_+_79629074 5.36 ENSMUST00000029388.8
RIKEN cDNA 4930579G24 gene
chr16_-_18811615 5.35 ENSMUST00000096990.3
cell division cycle 45
chr9_+_81863744 5.33 ENSMUST00000057067.3
meiosis-specific, MEI4 homolog (S. cerevisiae)
chr10_+_40883469 5.27 ENSMUST00000019975.7
WAS protein family, member 1
chr11_-_4704334 5.26 ENSMUST00000058407.5
ubiquinol-cytochrome c reductase, complex III subunit X
chr10_-_100487267 5.26 ENSMUST00000128009.1
transmembrane and tetratricopeptide repeat containing 3
chr3_+_85574109 5.26 ENSMUST00000127348.1
ENSMUST00000107672.1
ENSMUST00000107674.1
PET112 homolog (S. cerevisiae)
chr15_+_78428650 5.24 ENSMUST00000159771.1
potassium channel tetramerisation domain containing 17
chr10_+_128015157 5.18 ENSMUST00000178041.1
ENSMUST00000026461.7
DNA primase, p49 subunit
chr9_+_83548309 5.18 ENSMUST00000113215.3
SH3 domain binding glutamic acid-rich protein like 2
chr4_-_49521036 5.12 ENSMUST00000057829.3
mitochondrial ribosomal protein L50
chr1_-_60098135 5.03 ENSMUST00000141417.1
ENSMUST00000122038.1
WD repeat domain 12
chr7_+_29307924 4.98 ENSMUST00000108230.1
ENSMUST00000065181.5
D4, zinc and double PHD fingers family 1
chr10_-_41809607 4.93 ENSMUST00000019951.9
centrosomal protein 57-like 1
chr8_-_57487801 4.90 ENSMUST00000034022.3
sin3 associated polypeptide
chr1_-_60097893 4.85 ENSMUST00000027173.8
WD repeat domain 12
chr1_+_172482199 4.82 ENSMUST00000135267.1
ENSMUST00000052629.6
ENSMUST00000111235.2
immunoglobulin superfamily, member 9
chr17_-_35673738 4.78 ENSMUST00000001565.8
general transcription factor II H, polypeptide 4
chr2_+_152962485 4.74 ENSMUST00000099197.2
ENSMUST00000103155.3
tubulin tyrosine ligase-like family, member 9
chr12_+_79297345 4.71 ENSMUST00000079533.5
ENSMUST00000171210.1
RAD51 homolog B
chr14_-_54517353 4.69 ENSMUST00000023873.5
protein arginine N-methyltransferase 5
chr7_+_29303938 4.64 ENSMUST00000108231.1
D4, zinc and double PHD fingers family 1
chr7_+_101663705 4.63 ENSMUST00000106998.1
ClpB caseinolytic peptidase B
chr4_-_107178282 4.59 ENSMUST00000058585.7
transcription elongation factor A (SII) N-terminal and central domain containing 2
chr2_+_167062934 4.58 ENSMUST00000125674.1
RIKEN cDNA 1500012F01 gene
chr19_+_53329413 4.56 ENSMUST00000025998.7
Max interacting protein 1
chr16_+_35983424 4.54 ENSMUST00000173555.1
karyopherin (importin) alpha 1
chr5_+_33658567 4.46 ENSMUST00000114426.3
transforming, acidic coiled-coil containing protein 3
chr11_+_98907801 4.46 ENSMUST00000092706.6
cell division cycle 6
chr5_-_34660068 4.45 ENSMUST00000041364.9
NOP14 nucleolar protein
chr15_-_9140374 4.40 ENSMUST00000096482.3
ENSMUST00000110585.2
S-phase kinase-associated protein 2 (p45)
chr5_-_134314637 4.40 ENSMUST00000173504.1
general transcription factor II I
chr13_-_110280103 4.38 ENSMUST00000167824.1
RAB3C, member RAS oncogene family
chr4_+_116807714 4.37 ENSMUST00000102699.1
ENSMUST00000130359.1
mutY homolog (E. coli)
chr2_+_71055731 4.36 ENSMUST00000154704.1
ENSMUST00000135357.1
ENSMUST00000064141.5
ENSMUST00000112159.2
ENSMUST00000102701.3
DDB1 and CUL4 associated factor 17
chr10_-_81496313 4.29 ENSMUST00000118498.1
nicalin homolog (zebrafish)
chr2_-_71055534 4.27 ENSMUST00000090849.5
ENSMUST00000100037.2
ENSMUST00000112186.2
methyltransferase like 8
chr10_+_84917616 4.26 ENSMUST00000038523.7
ENSMUST00000095385.3
resistance to inhibitors of cholinesterase 8 homolog B (C. elegans)
chr7_+_101663633 4.23 ENSMUST00000001884.7
ClpB caseinolytic peptidase B
chr18_-_42262053 4.20 ENSMUST00000097590.3
leucyl-tRNA synthetase
chr15_+_76904070 4.20 ENSMUST00000004072.8
ribosomal protein L8
chrY_+_90785442 4.20 ENSMUST00000177591.1
ENSMUST00000177671.1
ENSMUST00000179077.1
erythroid differentiation regulator 1
chr6_+_35177386 4.18 ENSMUST00000043815.9
nucleoporin 205
chr10_+_80142358 4.11 ENSMUST00000105366.1
ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit
chr10_+_80142295 4.08 ENSMUST00000003156.8
ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit
chr16_-_18811972 4.05 ENSMUST00000000028.7
ENSMUST00000115585.1
cell division cycle 45
chr1_-_128103016 3.99 ENSMUST00000097597.2
zinc finger, RAN-binding domain containing 3
chr9_-_98601642 3.94 ENSMUST00000035034.8
mitochondrial ribosomal protein S22
chr5_+_136919137 3.90 ENSMUST00000181045.1
RIKEN cDNA 4933404O12 gene
chrX_-_162829379 3.90 ENSMUST00000041370.4
ENSMUST00000112316.2
ENSMUST00000112315.1
taxilin gamma
chr8_-_124721956 3.85 ENSMUST00000117624.1
ENSMUST00000041614.8
ENSMUST00000118134.1
tetratricopeptide repeat domain 13
chr5_-_134314378 3.85 ENSMUST00000174867.1
general transcription factor II I
chr11_+_116671658 3.84 ENSMUST00000106378.1
ENSMUST00000144049.1
RIKEN cDNA 1810032O08 gene
chr1_+_181150926 3.82 ENSMUST00000134115.1
ENSMUST00000111059.1
cornichon homolog 4 (Drosophila)
chr10_-_128626464 3.82 ENSMUST00000026420.5
ribosomal protein S26
chr4_-_116708312 3.73 ENSMUST00000030453.4
methylmalonic aciduria cblC type, with homocystinuria
chr11_-_77489666 3.72 ENSMUST00000037593.7
ENSMUST00000092892.3
ankyrin repeat domain 13b
chr5_+_33658550 3.71 ENSMUST00000152847.1
transforming, acidic coiled-coil containing protein 3
chr15_-_76639840 3.62 ENSMUST00000166974.1
ENSMUST00000168185.1
tonsoku-like, DNA repair protein
chr7_-_45830776 3.62 ENSMUST00000107723.2
ENSMUST00000131384.1
glutamate-rich WD repeat containing 1
chr7_+_100227311 3.61 ENSMUST00000084935.3
phosphoglucomutase 2-like 1
chr13_+_106947104 3.59 ENSMUST00000022203.8
DIM1 dimethyladenosine transferase 1-like (S. cerevisiae)
chrX_-_139998519 3.55 ENSMUST00000113007.1
ENSMUST00000033810.7
ENSMUST00000113011.2
ENSMUST00000087400.5
RNA binding motif protein 41
chr16_+_43889936 3.54 ENSMUST00000151183.1
RIKEN cDNA 2610015P09 gene
chr6_-_83054415 3.54 ENSMUST00000113962.1
ENSMUST00000089645.6
ENSMUST00000113963.1
HtrA serine peptidase 2
chr15_+_34495302 3.53 ENSMUST00000052290.7
ENSMUST00000079028.5
processing of precursor 1, ribonuclease P/MRP family, (S. cerevisiae)
chr4_+_126556994 3.53 ENSMUST00000147675.1
claspin
chr2_-_155074447 3.52 ENSMUST00000137242.1
ENSMUST00000054607.9
S-adenosylhomocysteine hydrolase
chr11_-_78183551 3.51 ENSMUST00000102483.4
ribosomal protein L23A
chr17_+_24632671 3.50 ENSMUST00000047611.2
nth (endonuclease III)-like 1 (E.coli)
chr1_+_172481788 3.49 ENSMUST00000127052.1
immunoglobulin superfamily, member 9
chr8_-_105707933 3.47 ENSMUST00000013299.9
enkurin domain containing 1
chr6_-_120357440 3.46 ENSMUST00000112703.1
coiled-coil domain containing 77
chr12_+_87266696 3.43 ENSMUST00000021425.6
AHA1, activator of heat shock protein ATPase 1
chr19_+_5601854 3.40 ENSMUST00000025864.4
ribonuclease H2, subunit C
chr6_-_120357342 3.40 ENSMUST00000163827.1
coiled-coil domain containing 77
chr12_+_40446050 3.37 ENSMUST00000037488.6
dedicator of cytokinesis 4
chr1_-_128102412 3.34 ENSMUST00000112538.1
ENSMUST00000086614.5
zinc finger, RAN-binding domain containing 3
chr7_-_4445181 3.33 ENSMUST00000138798.1
retinol dehydrogenase 13 (all-trans and 9-cis)
chr1_+_179803376 3.30 ENSMUST00000097454.2
predicted gene 10518
chr11_-_100712429 3.29 ENSMUST00000006973.5
ENSMUST00000103118.3
K(lysine) acetyltransferase 2A
chr17_-_25727364 3.28 ENSMUST00000170070.1
ENSMUST00000048054.7
CTF18, chromosome transmission fidelity factor 18
chr4_+_62408770 3.26 ENSMUST00000084524.3
PRP4 pre-mRNA processing factor 4 homolog (yeast)
chr8_-_72443772 3.24 ENSMUST00000019876.5
calreticulin 3
chr2_-_69206146 3.24 ENSMUST00000127243.1
ENSMUST00000149643.1
ENSMUST00000167875.2
ENSMUST00000005365.8
SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae)
chr8_-_92355764 3.22 ENSMUST00000180102.1
ENSMUST00000179421.1
ENSMUST00000179222.1
ENSMUST00000179029.1
RIKEN cDNA 4933436C20 gene
chr9_-_57552760 3.11 ENSMUST00000034856.8
mannose phosphate isomerase
chr13_-_54468805 3.10 ENSMUST00000026990.5
THO complex 3
chr6_+_71909046 3.10 ENSMUST00000055296.8
polymerase (RNA) I polypeptide A
chr10_-_127522428 3.10 ENSMUST00000026470.4
serine hydroxymethyltransferase 2 (mitochondrial)
chr12_+_106010263 3.06 ENSMUST00000021539.8
ENSMUST00000085026.4
ENSMUST00000072040.5
vaccinia related kinase 1
chr7_+_126861947 3.05 ENSMUST00000037248.3
HIRA interacting protein 3
chr17_+_84626458 3.03 ENSMUST00000025101.8
dynein cytoplasmic 2 light intermediate chain 1
chr15_-_44428303 3.01 ENSMUST00000038719.6
NudC domain containing 1
chr6_-_128437653 3.00 ENSMUST00000151796.1
FK506 binding protein 4
chr6_+_108213086 2.98 ENSMUST00000032192.6
inositol 1,4,5-trisphosphate receptor 1
chrX_-_8252304 2.96 ENSMUST00000115594.1
FtsJ homolog 1 (E. coli)
chr2_-_77946180 2.96 ENSMUST00000111824.1
ENSMUST00000111819.1
ENSMUST00000128963.1
CWC22 spliceosome-associated protein homolog (S. cerevisiae)
chr2_-_69206133 2.95 ENSMUST00000112320.1
SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae)
chr14_+_64950037 2.95 ENSMUST00000043914.5
integrator complex subunit 9
chr8_-_105851981 2.92 ENSMUST00000040776.4
centromere protein T
chr11_+_29547950 2.92 ENSMUST00000020753.3
clathrin heavy chain linker domain containing 1
chr8_-_70897407 2.92 ENSMUST00000054220.8
ribosomal protein L18A
chr7_-_99483645 2.91 ENSMUST00000107096.1
ENSMUST00000032998.6
ribosomal protein S3
chr6_-_87672142 2.91 ENSMUST00000032130.2
ENSMUST00000065997.2
aprataxin and PNKP like factor
chr11_-_29547820 2.89 ENSMUST00000102844.3
ribosomal protein S27A
chr14_-_87141206 2.85 ENSMUST00000022599.7
diaphanous homolog 3 (Drosophila)
chr4_-_126202335 2.85 ENSMUST00000142125.1
ENSMUST00000106141.2
thyroid hormone receptor associated protein 3
chr1_-_179803625 2.84 ENSMUST00000027768.7
AT hook containing transcription factor 1
chr6_-_120357422 2.84 ENSMUST00000032283.5
coiled-coil domain containing 77
chr17_-_35838208 2.80 ENSMUST00000134978.2
tubulin, beta 5 class I
chr9_+_108296853 2.78 ENSMUST00000035230.5
aminomethyltransferase
chr8_+_124722139 2.77 ENSMUST00000034463.3
ARV1 homolog (yeast)
chr2_-_27475600 2.75 ENSMUST00000147736.1
bromodomain containing 3
chr12_-_79192248 2.73 ENSMUST00000161204.1
retinol dehydrogenase 11
chr6_+_21985903 2.72 ENSMUST00000137437.1
ENSMUST00000115383.2
cadherin-like and PC-esterase domain containing 1
chr4_-_139352538 2.69 ENSMUST00000102503.3
MRT4, mRNA turnover 4, homolog (S. cerevisiae)
chr1_-_177796451 2.69 ENSMUST00000016105.8
adenylosuccinate synthetase, non muscle
chr7_-_89941196 2.63 ENSMUST00000117354.1
lethal, Chr 7, Rinchik 6
chr18_+_34625009 2.60 ENSMUST00000166044.1
kinesin family member 20A
chr4_-_139352298 2.60 ENSMUST00000030513.6
ENSMUST00000155257.1
MRT4, mRNA turnover 4, homolog (S. cerevisiae)
chr11_-_70015346 2.59 ENSMUST00000018718.7
ENSMUST00000102574.3
acyl-Coenzyme A dehydrogenase, very long chain
chr7_+_122159422 2.59 ENSMUST00000033154.6
polo-like kinase 1
chr17_-_35838259 2.56 ENSMUST00000001566.8
tubulin, beta 5 class I

Network of associatons between targets according to the STRING database.

First level regulatory network of Hcfc1_Six5_Smarcc2_Zfp143

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
7.0 21.0 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
4.1 24.4 GO:0031536 positive regulation of exit from mitosis(GO:0031536)
3.7 11.2 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
3.2 22.4 GO:0033567 DNA replication, Okazaki fragment processing(GO:0033567)
3.1 9.4 GO:1902299 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) DNA replication preinitiation complex assembly(GO:0071163) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
3.1 18.4 GO:0098838 reduced folate transmembrane transport(GO:0098838)
2.5 7.5 GO:0042851 L-alanine metabolic process(GO:0042851)
2.4 7.3 GO:0036292 DNA rewinding(GO:0036292)
2.2 8.7 GO:1990414 replication-born double-strand break repair via sister chromatid exchange(GO:1990414)
2.1 6.2 GO:0090204 protein localization to nuclear pore(GO:0090204) negative regulation of vascular endothelial growth factor production(GO:1904046)
2.1 6.2 GO:0051329 interphase(GO:0051325) mitotic interphase(GO:0051329)
1.9 9.4 GO:0014886 transition between slow and fast fiber(GO:0014886)
1.8 22.1 GO:0001682 tRNA 5'-leader removal(GO:0001682)
1.8 9.2 GO:0034421 post-translational protein acetylation(GO:0034421)
1.8 9.0 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
1.6 11.5 GO:1990416 cellular response to brain-derived neurotrophic factor stimulus(GO:1990416)
1.6 22.7 GO:0051292 nuclear pore complex assembly(GO:0051292)
1.5 2.9 GO:0051106 regulation of DNA ligation(GO:0051105) positive regulation of DNA ligation(GO:0051106)
1.4 4.3 GO:1905053 regulation of base-excision repair(GO:1905051) positive regulation of base-excision repair(GO:1905053)
1.4 5.8 GO:0071043 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
1.4 53.1 GO:0060236 regulation of mitotic spindle organization(GO:0060236)
1.4 15.1 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
1.4 5.5 GO:0099527 postsynapse to nucleus signaling pathway(GO:0099527)
1.3 17.0 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
1.3 6.5 GO:0060447 bud outgrowth involved in lung branching(GO:0060447)
1.3 3.9 GO:0002184 cytoplasmic translational termination(GO:0002184)
1.3 5.2 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
1.2 3.5 GO:0006285 base-excision repair, AP site formation(GO:0006285) nucleotide-excision repair, DNA incision, 5'-to lesion(GO:0006296)
1.2 6.9 GO:0035247 peptidyl-arginine omega-N-methylation(GO:0035247)
1.1 5.7 GO:0035720 intraciliary anterograde transport(GO:0035720)
1.1 6.8 GO:0003431 growth plate cartilage chondrocyte development(GO:0003431) positive regulation of centrosome duplication(GO:0010825)
1.1 11.2 GO:1905098 negative regulation of guanyl-nucleotide exchange factor activity(GO:1905098)
1.1 3.3 GO:0071929 alpha-tubulin acetylation(GO:0071929)
1.1 5.3 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
1.1 4.2 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
1.0 3.1 GO:0009298 GDP-mannose biosynthetic process(GO:0009298)
0.9 3.7 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.9 2.8 GO:0019464 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.9 5.4 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.9 2.7 GO:0044208 'de novo' AMP biosynthetic process(GO:0044208)
0.9 3.6 GO:0002439 chronic inflammatory response to antigenic stimulus(GO:0002439)
0.9 9.6 GO:0033314 mitotic DNA replication checkpoint(GO:0033314)
0.8 3.3 GO:0030974 thiamine pyrophosphate transport(GO:0030974)
0.8 7.1 GO:0009644 response to high light intensity(GO:0009644)
0.8 3.8 GO:0035405 histone-threonine phosphorylation(GO:0035405)
0.7 2.1 GO:0018214 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.7 5.0 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.7 13.2 GO:0007080 mitotic metaphase plate congression(GO:0007080)
0.7 4.8 GO:0071169 establishment of protein localization to chromatin(GO:0071169)
0.7 2.7 GO:0016062 adaptation of rhodopsin mediated signaling(GO:0016062) light adaption(GO:0036367)
0.6 3.1 GO:1904749 regulation of protein localization to nucleolus(GO:1904749)
0.6 3.1 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.6 1.8 GO:0046168 glycerol-3-phosphate catabolic process(GO:0046168)
0.6 2.4 GO:0032053 ciliary basal body organization(GO:0032053)
0.6 6.6 GO:0000920 cell separation after cytokinesis(GO:0000920)
0.6 4.2 GO:0009235 cobalamin metabolic process(GO:0009235)
0.6 11.3 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.6 3.5 GO:0060178 regulation of exocyst localization(GO:0060178)
0.6 8.0 GO:0033601 positive regulation of mammary gland epithelial cell proliferation(GO:0033601)
0.6 2.8 GO:1901525 negative regulation of macromitophagy(GO:1901525)
0.5 4.9 GO:0000070 mitotic sister chromatid segregation(GO:0000070)
0.5 6.3 GO:0016446 somatic hypermutation of immunoglobulin genes(GO:0016446)
0.5 1.0 GO:0071431 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.5 1.0 GO:0035246 peptidyl-arginine N-methylation(GO:0035246)
0.5 7.8 GO:0000212 meiotic spindle organization(GO:0000212)
0.5 1.5 GO:0042539 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.5 6.6 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977)
0.5 3.0 GO:0030422 production of siRNA involved in RNA interference(GO:0030422)
0.5 2.5 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.5 4.0 GO:0007000 nucleolus organization(GO:0007000)
0.5 1.5 GO:1901097 negative regulation of autophagosome maturation(GO:1901097)
0.5 4.9 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.5 0.5 GO:0000720 pyrimidine dimer repair by nucleotide-excision repair(GO:0000720)
0.5 5.3 GO:0097033 respiratory chain complex III assembly(GO:0017062) mitochondrial respiratory chain complex III assembly(GO:0034551) mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.5 3.3 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.5 2.3 GO:1902775 mitochondrial large ribosomal subunit assembly(GO:1902775)
0.5 6.0 GO:0051984 positive regulation of chromosome segregation(GO:0051984)
0.5 2.3 GO:0090666 scaRNA localization to Cajal body(GO:0090666)
0.4 1.3 GO:1902990 leading strand elongation(GO:0006272) mitotic telomere maintenance via semi-conservative replication(GO:1902990)
0.4 0.9 GO:0034085 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.4 3.5 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.4 13.7 GO:0030488 tRNA methylation(GO:0030488)
0.4 4.3 GO:0080009 mRNA methylation(GO:0080009)
0.4 2.6 GO:0045917 positive regulation of complement activation(GO:0045917) progesterone receptor signaling pathway(GO:0050847) positive regulation of protein activation cascade(GO:2000259)
0.4 6.7 GO:1902916 positive regulation of protein polyubiquitination(GO:1902916)
0.4 1.7 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.4 1.2 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350)
0.4 10.5 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.4 0.8 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.4 2.8 GO:0032380 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.4 2.4 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.4 1.9 GO:0000055 ribosomal large subunit export from nucleus(GO:0000055)
0.4 0.8 GO:0072717 cellular response to actinomycin D(GO:0072717)
0.4 3.8 GO:0042045 epithelial fluid transport(GO:0042045)
0.4 3.8 GO:0003373 dynamin polymerization involved in membrane fission(GO:0003373) dynamin polymerization involved in mitochondrial fission(GO:0003374)
0.4 1.1 GO:1902277 negative regulation of pancreatic amylase secretion(GO:1902277)
0.4 8.8 GO:0015858 nucleoside transport(GO:0015858)
0.4 1.4 GO:1990928 response to amino acid starvation(GO:1990928)
0.4 1.1 GO:0098968 neurotransmitter receptor transport postsynaptic membrane to endosome(GO:0098968)
0.3 0.7 GO:0016080 synaptic vesicle targeting(GO:0016080)
0.3 2.1 GO:0090154 positive regulation of sphingolipid biosynthetic process(GO:0090154) positive regulation of ceramide biosynthetic process(GO:2000304)
0.3 12.2 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.3 0.3 GO:0010571 positive regulation of nuclear cell cycle DNA replication(GO:0010571) positive regulation of DNA-dependent DNA replication(GO:2000105)
0.3 0.6 GO:0051902 negative regulation of mitochondrial depolarization(GO:0051902)
0.3 3.8 GO:0051988 regulation of attachment of spindle microtubules to kinetochore(GO:0051988)
0.3 1.0 GO:0043686 co-translational protein modification(GO:0043686)
0.3 2.8 GO:0034501 protein localization to kinetochore(GO:0034501)
0.3 2.5 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.3 1.5 GO:0014022 neural plate elongation(GO:0014022) convergent extension involved in neural plate elongation(GO:0022007)
0.3 0.3 GO:0043465 regulation of fermentation(GO:0043465) regulation of NAD metabolic process(GO:1902688) regulation of glucose catabolic process to lactate via pyruvate(GO:1904023)
0.3 5.7 GO:0000154 rRNA modification(GO:0000154)
0.3 7.5 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.3 0.9 GO:2000616 negative regulation of histone H3-K9 acetylation(GO:2000616)
0.3 0.9 GO:2000554 regulation of T-helper 1 cell cytokine production(GO:2000554) positive regulation of T-helper 1 cell cytokine production(GO:2000556)
0.3 1.3 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.3 1.3 GO:0075525 viral translational termination-reinitiation(GO:0075525)
0.3 4.3 GO:0042407 cristae formation(GO:0042407)
0.3 0.8 GO:0002276 basophil activation involved in immune response(GO:0002276)
0.3 2.1 GO:0046826 negative regulation of protein export from nucleus(GO:0046826)
0.3 2.0 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.3 2.0 GO:1903350 response to dopamine(GO:1903350) cellular response to dopamine(GO:1903351)
0.2 7.7 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.2 0.7 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.2 2.4 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.2 0.7 GO:0035928 rRNA import into mitochondrion(GO:0035928)
0.2 1.0 GO:0046368 GDP-L-fucose metabolic process(GO:0046368)
0.2 1.0 GO:0006624 vacuolar protein processing(GO:0006624)
0.2 7.1 GO:0006270 DNA replication initiation(GO:0006270)
0.2 3.1 GO:0008608 attachment of spindle microtubules to kinetochore(GO:0008608)
0.2 0.7 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.2 1.6 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.2 2.1 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.2 8.6 GO:0032469 endoplasmic reticulum calcium ion homeostasis(GO:0032469)
0.2 15.3 GO:0051225 spindle assembly(GO:0051225)
0.2 3.6 GO:0006337 nucleosome disassembly(GO:0006337)
0.2 0.9 GO:1901069 guanosine-containing compound catabolic process(GO:1901069)
0.2 2.2 GO:0000290 deadenylation-dependent decapping of nuclear-transcribed mRNA(GO:0000290)
0.2 0.7 GO:0060336 negative regulation of response to interferon-gamma(GO:0060331) negative regulation of interferon-gamma-mediated signaling pathway(GO:0060336)
0.2 2.4 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.2 0.7 GO:0006550 isoleucine catabolic process(GO:0006550)
0.2 0.6 GO:0036090 cleavage furrow ingression(GO:0036090)
0.2 0.6 GO:0006772 thiamine metabolic process(GO:0006772) thiamine-containing compound metabolic process(GO:0042723)
0.2 0.6 GO:0031053 primary miRNA processing(GO:0031053)
0.2 1.9 GO:0051974 negative regulation of telomerase activity(GO:0051974)
0.2 1.3 GO:0061641 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.2 2.5 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.2 3.1 GO:0033211 adiponectin-activated signaling pathway(GO:0033211)
0.2 1.4 GO:0017185 peptidyl-lysine hydroxylation(GO:0017185)
0.2 0.8 GO:0061086 negative regulation of histone H3-K27 methylation(GO:0061086)
0.2 2.3 GO:0000244 spliceosomal tri-snRNP complex assembly(GO:0000244)
0.2 6.9 GO:0033119 negative regulation of RNA splicing(GO:0033119)
0.2 4.9 GO:0007052 mitotic spindle organization(GO:0007052)
0.2 0.9 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.2 0.6 GO:0060912 cardiac cell fate specification(GO:0060912)
0.2 2.0 GO:0016114 terpenoid biosynthetic process(GO:0016114)
0.2 0.5 GO:1902774 late endosome to lysosome transport(GO:1902774)
0.2 1.1 GO:0034227 tRNA thio-modification(GO:0034227)
0.2 11.6 GO:0035019 somatic stem cell population maintenance(GO:0035019)
0.2 2.0 GO:0048341 paraxial mesoderm formation(GO:0048341)
0.2 2.5 GO:0031297 replication fork processing(GO:0031297)
0.2 0.9 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.2 0.9 GO:0030638 polyketide metabolic process(GO:0030638) aminoglycoside antibiotic metabolic process(GO:0030647) daunorubicin metabolic process(GO:0044597) doxorubicin metabolic process(GO:0044598)
0.2 0.5 GO:0036091 positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091) regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.2 1.0 GO:0097210 axonal transport of mitochondrion(GO:0019896) response to gonadotropin-releasing hormone(GO:0097210) cellular response to gonadotropin-releasing hormone(GO:0097211)
0.2 1.4 GO:0014029 neural crest formation(GO:0014029)
0.2 0.9 GO:0031860 telomeric 3' overhang formation(GO:0031860)
0.2 0.7 GO:0017182 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.2 0.7 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.2 2.2 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.2 2.6 GO:0043248 proteasome assembly(GO:0043248)
0.2 2.0 GO:0034351 negative regulation of glial cell apoptotic process(GO:0034351)
0.2 0.8 GO:0002121 inter-male aggressive behavior(GO:0002121)
0.2 8.1 GO:0030490 maturation of SSU-rRNA(GO:0030490)
0.2 0.8 GO:0008616 queuosine biosynthetic process(GO:0008616) queuosine metabolic process(GO:0046116)
0.2 3.4 GO:0016180 snRNA processing(GO:0016180)
0.2 0.3 GO:0060399 positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.2 0.8 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.2 2.2 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.2 0.9 GO:0070203 regulation of establishment of protein localization to telomere(GO:0070203) positive regulation of establishment of protein localization to telomere(GO:1904851)
0.1 8.5 GO:0006364 rRNA processing(GO:0006364)
0.1 3.7 GO:0030866 cortical actin cytoskeleton organization(GO:0030866)
0.1 2.4 GO:0052646 alditol phosphate metabolic process(GO:0052646)
0.1 2.0 GO:0002176 male germ cell proliferation(GO:0002176)
0.1 5.4 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.1 0.3 GO:0002362 CD4-positive, CD25-positive, alpha-beta regulatory T cell lineage commitment(GO:0002362)
0.1 2.7 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.1 8.2 GO:0034605 cellular response to heat(GO:0034605)
0.1 5.5 GO:0048255 mRNA stabilization(GO:0048255)
0.1 2.8 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.1 0.4 GO:0043461 proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.1 0.9 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.1 4.3 GO:0006284 base-excision repair(GO:0006284)
0.1 0.9 GO:0071971 extracellular exosome assembly(GO:0071971) regulation of extracellular exosome assembly(GO:1903551)
0.1 1.5 GO:0018206 peptidyl-methionine modification(GO:0018206)
0.1 0.9 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.1 1.6 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.1 0.8 GO:0035360 positive regulation of peroxisome proliferator activated receptor signaling pathway(GO:0035360)
0.1 0.4 GO:0000066 mitochondrial ornithine transport(GO:0000066)
0.1 0.1 GO:0090365 regulation of mRNA modification(GO:0090365)
0.1 0.5 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.1 2.0 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.1 1.1 GO:0098937 dendritic transport(GO:0098935) anterograde dendritic transport(GO:0098937)
0.1 0.8 GO:1990573 potassium ion import across plasma membrane(GO:1990573)
0.1 0.9 GO:0006265 DNA topological change(GO:0006265)
0.1 1.5 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.1 0.3 GO:1990927 calcium ion regulated lysosome exocytosis(GO:1990927)
0.1 0.5 GO:0034197 acylglycerol transport(GO:0034196) triglyceride transport(GO:0034197)
0.1 0.3 GO:2001160 regulation of histone H3-K79 methylation(GO:2001160)
0.1 1.3 GO:0035067 negative regulation of histone acetylation(GO:0035067)
0.1 0.3 GO:2000872 positive regulation of progesterone secretion(GO:2000872)
0.1 0.2 GO:0030043 actin filament fragmentation(GO:0030043)
0.1 0.1 GO:1904781 positive regulation of protein localization to centrosome(GO:1904781)
0.1 0.4 GO:0070245 positive regulation of thymocyte apoptotic process(GO:0070245)
0.1 0.1 GO:0060971 embryonic heart tube left/right pattern formation(GO:0060971)
0.1 0.5 GO:0060613 fat pad development(GO:0060613)
0.1 1.5 GO:0006622 protein targeting to lysosome(GO:0006622)
0.1 0.4 GO:0001306 age-dependent response to oxidative stress(GO:0001306) age-dependent general metabolic decline(GO:0007571)
0.1 0.5 GO:0071955 recycling endosome to Golgi transport(GO:0071955)
0.1 0.5 GO:0050747 positive regulation of lipoprotein metabolic process(GO:0050747)
0.1 0.9 GO:0097034 mitochondrial respiratory chain complex IV assembly(GO:0033617) mitochondrial respiratory chain complex IV biogenesis(GO:0097034)
0.1 1.1 GO:0090141 positive regulation of mitochondrial fission(GO:0090141)
0.1 0.3 GO:0032914 positive regulation of transforming growth factor beta1 production(GO:0032914)
0.1 1.7 GO:0060044 negative regulation of cardiac muscle cell proliferation(GO:0060044)
0.1 1.9 GO:0042921 glucocorticoid receptor signaling pathway(GO:0042921)
0.1 0.4 GO:0036112 medium-chain fatty-acyl-CoA metabolic process(GO:0036112)
0.1 0.7 GO:0045046 peroxisomal membrane transport(GO:0015919) protein import into peroxisome membrane(GO:0045046)
0.1 9.2 GO:0000910 cytokinesis(GO:0000910)
0.1 2.5 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.1 3.6 GO:0002181 cytoplasmic translation(GO:0002181)
0.1 0.7 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.1 1.7 GO:0006607 NLS-bearing protein import into nucleus(GO:0006607)
0.1 17.4 GO:0000375 RNA splicing, via transesterification reactions(GO:0000375)
0.1 1.7 GO:0019370 leukotriene biosynthetic process(GO:0019370)
0.1 0.5 GO:0006122 mitochondrial electron transport, ubiquinol to cytochrome c(GO:0006122)
0.1 1.6 GO:0071480 cellular response to gamma radiation(GO:0071480)
0.1 0.7 GO:0006104 succinyl-CoA metabolic process(GO:0006104)
0.1 0.2 GO:2001034 positive regulation of double-strand break repair via nonhomologous end joining(GO:2001034)
0.1 1.4 GO:0031163 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.1 0.3 GO:0072385 minus-end-directed organelle transport along microtubule(GO:0072385)
0.1 0.3 GO:0036265 7-methylguanosine mRNA capping(GO:0006370) RNA (guanine-N7)-methylation(GO:0036265)
0.1 0.9 GO:0070831 basement membrane assembly(GO:0070831)
0.1 0.2 GO:0010040 response to iron(II) ion(GO:0010040)
0.1 0.2 GO:0070200 establishment of protein localization to telomere(GO:0070200)
0.1 0.2 GO:0034392 negative regulation of smooth muscle cell apoptotic process(GO:0034392)
0.1 1.0 GO:0006968 cellular defense response(GO:0006968)
0.1 0.6 GO:0008063 Toll signaling pathway(GO:0008063)
0.1 3.3 GO:0006401 RNA catabolic process(GO:0006401)
0.1 0.4 GO:0033182 regulation of histone ubiquitination(GO:0033182)
0.1 0.7 GO:0045719 negative regulation of glycogen biosynthetic process(GO:0045719)
0.1 1.1 GO:0035024 negative regulation of Rho protein signal transduction(GO:0035024)
0.1 0.4 GO:0010747 positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747)
0.1 0.5 GO:0090435 protein localization to nuclear envelope(GO:0090435)
0.1 0.9 GO:1902751 positive regulation of cell cycle G2/M phase transition(GO:1902751)
0.1 0.1 GO:0072236 metanephric loop of Henle development(GO:0072236)
0.1 2.6 GO:0042254 ribosome biogenesis(GO:0042254)
0.1 0.7 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.1 0.2 GO:2000210 positive regulation of anoikis(GO:2000210)
0.1 1.3 GO:0042775 mitochondrial ATP synthesis coupled electron transport(GO:0042775)
0.1 0.6 GO:0070914 UV-damage excision repair(GO:0070914)
0.1 0.2 GO:0018197 peptidyl-aspartic acid modification(GO:0018197) cellular response to manganese ion(GO:0071287)
0.1 0.2 GO:0000730 DNA recombinase assembly(GO:0000730) double-strand break repair via synthesis-dependent strand annealing(GO:0045003)
0.1 0.6 GO:0060710 chorio-allantoic fusion(GO:0060710)
0.1 5.7 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.1 0.2 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.1 0.2 GO:0009197 dUDP biosynthetic process(GO:0006227) pyrimidine nucleoside diphosphate metabolic process(GO:0009138) pyrimidine nucleoside diphosphate biosynthetic process(GO:0009139) pyrimidine deoxyribonucleoside diphosphate metabolic process(GO:0009196) pyrimidine deoxyribonucleoside diphosphate biosynthetic process(GO:0009197) dUDP metabolic process(GO:0046077)
0.1 0.8 GO:2001241 positive regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001241)
0.1 0.5 GO:0018344 protein geranylgeranylation(GO:0018344)
0.1 0.3 GO:0019372 lipoxygenase pathway(GO:0019372)
0.1 4.6 GO:0035914 skeletal muscle cell differentiation(GO:0035914)
0.1 0.4 GO:0061002 negative regulation of dendritic spine morphogenesis(GO:0061002)
0.1 11.8 GO:0007411 axon guidance(GO:0007411)
0.1 0.2 GO:0048703 embryonic viscerocranium morphogenesis(GO:0048703)
0.1 0.7 GO:0031100 organ regeneration(GO:0031100)
0.1 0.4 GO:0010992 ubiquitin homeostasis(GO:0010992)
0.1 1.4 GO:1901099 negative regulation of signal transduction in absence of ligand(GO:1901099) negative regulation of extrinsic apoptotic signaling pathway in absence of ligand(GO:2001240)
0.1 0.3 GO:1900121 negative regulation of receptor binding(GO:1900121)
0.1 0.7 GO:0030049 muscle filament sliding(GO:0030049)
0.1 0.4 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.0 0.7 GO:0045943 positive regulation of transcription from RNA polymerase I promoter(GO:0045943)
0.0 21.3 GO:0051301 cell division(GO:0051301)
0.0 0.6 GO:0051085 chaperone mediated protein folding requiring cofactor(GO:0051085)
0.0 0.1 GO:0061470 T follicular helper cell differentiation(GO:0061470)
0.0 0.7 GO:0019430 removal of superoxide radicals(GO:0019430)
0.0 0.3 GO:0051967 negative regulation of synaptic transmission, glutamatergic(GO:0051967)
0.0 0.2 GO:2001270 regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001270)
0.0 0.2 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.6 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 1.2 GO:0006754 ATP biosynthetic process(GO:0006754)
0.0 0.3 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.0 0.2 GO:0033147 negative regulation of intracellular estrogen receptor signaling pathway(GO:0033147)
0.0 0.5 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 0.3 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.0 1.3 GO:0006379 mRNA cleavage(GO:0006379)
0.0 0.2 GO:0007062 sister chromatid cohesion(GO:0007062)
0.0 0.8 GO:1900087 positive regulation of G1/S transition of mitotic cell cycle(GO:1900087)
0.0 1.2 GO:0001541 ovarian follicle development(GO:0001541)
0.0 1.3 GO:0043297 apical junction assembly(GO:0043297)
0.0 1.2 GO:0034198 cellular response to amino acid starvation(GO:0034198)
0.0 0.0 GO:0016441 posttranscriptional gene silencing(GO:0016441) posttranscriptional gene silencing by RNA(GO:0035194)
0.0 0.5 GO:1904294 positive regulation of ERAD pathway(GO:1904294)
0.0 0.2 GO:1903800 positive regulation of production of miRNAs involved in gene silencing by miRNA(GO:1903800)
0.0 16.0 GO:0006412 translation(GO:0006412)
0.0 1.7 GO:0018279 peptidyl-asparagine modification(GO:0018196) protein N-linked glycosylation via asparagine(GO:0018279)
0.0 0.8 GO:0006611 protein export from nucleus(GO:0006611)
0.0 3.6 GO:0019882 antigen processing and presentation(GO:0019882)
0.0 0.5 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.5 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 0.1 GO:0009446 putrescine biosynthetic process(GO:0009446)
0.0 0.1 GO:0006116 NADH oxidation(GO:0006116)
0.0 0.6 GO:0045116 protein neddylation(GO:0045116)
0.0 0.4 GO:0046520 sphingosine biosynthetic process(GO:0046512) sphingoid biosynthetic process(GO:0046520)
0.0 0.3 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.4 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 0.5 GO:0070208 protein heterotrimerization(GO:0070208)
0.0 0.2 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.0 0.4 GO:0090161 Golgi ribbon formation(GO:0090161)
0.0 0.1 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.0 0.2 GO:0010764 negative regulation of fibroblast migration(GO:0010764)
0.0 0.1 GO:0006264 mitochondrial DNA replication(GO:0006264)
0.0 0.1 GO:0006842 tricarboxylic acid transport(GO:0006842) citrate transport(GO:0015746)
0.0 0.1 GO:0030579 ubiquitin-dependent SMAD protein catabolic process(GO:0030579)
0.0 0.9 GO:0070206 protein trimerization(GO:0070206)
0.0 0.1 GO:0036066 protein O-linked fucosylation(GO:0036066)
0.0 0.2 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.0 0.2 GO:0034508 centromere complex assembly(GO:0034508)
0.0 0.3 GO:0071361 cellular response to ethanol(GO:0071361)
0.0 0.2 GO:0051443 positive regulation of ubiquitin-protein transferase activity(GO:0051443)
0.0 0.3 GO:0006105 succinate metabolic process(GO:0006105)
0.0 1.0 GO:0002090 regulation of receptor internalization(GO:0002090)
0.0 0.0 GO:0090343 positive regulation of cell aging(GO:0090343)
0.0 0.1 GO:0097298 regulation of nucleus size(GO:0097298)
0.0 0.0 GO:0090076 relaxation of skeletal muscle(GO:0090076)
0.0 1.1 GO:0042475 odontogenesis of dentin-containing tooth(GO:0042475)
0.0 0.2 GO:0003334 keratinocyte development(GO:0003334)
0.0 0.1 GO:0036151 phosphatidylcholine acyl-chain remodeling(GO:0036151)
0.0 0.3 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.0 0.3 GO:0006744 ubiquinone metabolic process(GO:0006743) ubiquinone biosynthetic process(GO:0006744)
0.0 1.1 GO:0030500 regulation of bone mineralization(GO:0030500)
0.0 0.2 GO:0090261 positive regulation of inclusion body assembly(GO:0090261)
0.0 2.1 GO:1990823 response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)
0.0 0.3 GO:0060632 regulation of microtubule-based movement(GO:0060632)
0.0 1.1 GO:0050729 positive regulation of inflammatory response(GO:0050729)
0.0 0.2 GO:0030889 negative regulation of B cell proliferation(GO:0030889)
0.0 0.4 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.1 GO:0070234 positive regulation of T cell apoptotic process(GO:0070234)
0.0 0.0 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185) synaptic vesicle budding(GO:0070142)
0.0 0.3 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.1 GO:2000270 negative regulation of fibroblast apoptotic process(GO:2000270)
0.0 0.3 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.0 0.1 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0 2.0 GO:0048167 regulation of synaptic plasticity(GO:0048167)
0.0 0.2 GO:0010592 positive regulation of lamellipodium assembly(GO:0010592)
0.0 0.0 GO:0042275 error-free postreplication DNA repair(GO:0042275)
0.0 0.2 GO:0001709 cell fate determination(GO:0001709)
0.0 0.2 GO:0030262 apoptotic nuclear changes(GO:0030262)
0.0 1.2 GO:0007368 determination of left/right symmetry(GO:0007368)
0.0 0.1 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.0 0.0 GO:0006999 nuclear pore organization(GO:0006999)
0.0 0.3 GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0007157)
0.0 1.3 GO:0002244 hematopoietic progenitor cell differentiation(GO:0002244)
0.0 0.0 GO:0052422 modulation by symbiont of host molecular function(GO:0052055) modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422)
0.0 0.1 GO:0080182 histone H3-K4 trimethylation(GO:0080182)
0.0 0.4 GO:0045069 regulation of viral genome replication(GO:0045069)
0.0 0.1 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.8 GO:0050728 negative regulation of inflammatory response(GO:0050728)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
5.7 34.0 GO:0032133 chromosome passenger complex(GO:0032133)
3.5 28.4 GO:0005818 aster(GO:0005818)
3.1 9.4 GO:0005656 nuclear pre-replicative complex(GO:0005656) pre-replicative complex(GO:0036387)
3.1 3.1 GO:0070552 BRISC complex(GO:0070552)
3.0 20.9 GO:0005655 nucleolar ribonuclease P complex(GO:0005655)
2.8 11.4 GO:0000438 core TFIIH complex portion of holo TFIIH complex(GO:0000438)
2.2 6.5 GO:0044614 nuclear pore cytoplasmic filaments(GO:0044614)
1.9 9.5 GO:0044611 nuclear pore inner ring(GO:0044611)
1.9 11.4 GO:0070531 BRCA1-A complex(GO:0070531)
1.8 23.5 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
1.7 17.0 GO:0070545 PeBoW complex(GO:0070545)
1.5 15.1 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
1.3 3.9 GO:0018444 translation release factor complex(GO:0018444)
1.2 6.2 GO:0031262 Ndc80 complex(GO:0031262)
1.2 3.6 GO:0035101 FACT complex(GO:0035101)
1.1 9.0 GO:0070652 HAUS complex(GO:0070652)
1.1 5.5 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
1.1 3.3 GO:0071001 U4/U6 snRNP(GO:0071001)
1.0 23.0 GO:0010369 chromocenter(GO:0010369)
1.0 5.2 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
1.0 8.2 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
1.0 3.0 GO:1990423 RZZ complex(GO:1990423)
1.0 3.0 GO:0031088 platelet dense granule membrane(GO:0031088)
1.0 4.9 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.9 4.7 GO:0030689 Noc complex(GO:0030689)
0.9 5.5 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.9 11.4 GO:0031209 SCAR complex(GO:0031209)
0.8 5.9 GO:0005638 lamin filament(GO:0005638)
0.8 4.0 GO:0044615 nuclear pore nuclear basket(GO:0044615)
0.8 6.2 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.7 2.0 GO:0098842 postsynaptic early endosome(GO:0098842)
0.7 2.0 GO:0070557 PCNA-p21 complex(GO:0070557)
0.6 1.9 GO:0055087 Ski complex(GO:0055087)
0.6 10.2 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.6 2.5 GO:0090661 box H/ACA telomerase RNP complex(GO:0090661)
0.6 4.3 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.6 1.8 GO:0033186 CAF-1 complex(GO:0033186)
0.6 6.1 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750)
0.6 15.2 GO:0071565 nBAF complex(GO:0071565)
0.6 6.6 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.5 5.9 GO:0042405 nuclear inclusion body(GO:0042405)
0.5 5.4 GO:0045298 tubulin complex(GO:0045298)
0.5 4.3 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.5 5.3 GO:0034709 methylosome(GO:0034709)
0.5 3.3 GO:0097255 R2TP complex(GO:0097255)
0.5 5.9 GO:0097542 ciliary tip(GO:0097542)
0.5 3.2 GO:0005687 U4 snRNP(GO:0005687)
0.4 5.8 GO:0042555 MCM complex(GO:0042555)
0.4 2.6 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.4 4.4 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.4 13.9 GO:0035371 microtubule plus-end(GO:0035371)
0.4 0.8 GO:0005683 U7 snRNP(GO:0005683)
0.4 11.2 GO:0000800 lateral element(GO:0000800)
0.4 25.2 GO:0005643 nuclear pore(GO:0005643)
0.4 1.1 GO:0005673 transcription factor TFIIE complex(GO:0005673)
0.4 1.8 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.4 3.3 GO:0061617 MICOS complex(GO:0061617)
0.4 2.9 GO:0000788 nuclear nucleosome(GO:0000788)
0.4 3.3 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.3 3.5 GO:0000796 condensin complex(GO:0000796)
0.3 19.3 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.3 3.0 GO:0070578 RISC-loading complex(GO:0070578)
0.3 2.0 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.3 5.8 GO:0035102 PRC1 complex(GO:0035102)
0.3 3.6 GO:0005686 U2 snRNP(GO:0005686)
0.3 2.1 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.3 1.5 GO:0070876 SOSS complex(GO:0070876)
0.3 14.8 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.3 2.4 GO:0035748 myelin sheath abaxonal region(GO:0035748)
0.3 21.0 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.3 4.7 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.3 3.8 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.3 1.1 GO:0033185 dolichol-phosphate-mannose synthase complex(GO:0033185)
0.3 2.8 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.3 1.9 GO:0032584 growth cone membrane(GO:0032584)
0.3 1.3 GO:0097361 CIA complex(GO:0097361)
0.3 1.3 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.3 6.9 GO:0051233 spindle midzone(GO:0051233)
0.2 2.0 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.2 4.3 GO:0005671 Ada2/Gcn5/Ada3 transcription activator complex(GO:0005671)
0.2 9.2 GO:0060077 inhibitory synapse(GO:0060077)
0.2 0.7 GO:0031251 PAN complex(GO:0031251)
0.2 3.5 GO:0035631 CD40 receptor complex(GO:0035631)
0.2 0.9 GO:0043259 laminin-1 complex(GO:0005606) laminin-10 complex(GO:0043259)
0.2 2.6 GO:0005838 proteasome regulatory particle(GO:0005838)
0.2 6.9 GO:0043596 nuclear replication fork(GO:0043596)
0.2 4.3 GO:0016580 Sin3 complex(GO:0016580)
0.2 1.1 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.2 2.7 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.2 28.4 GO:0005913 cell-cell adherens junction(GO:0005913)
0.2 1.8 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.2 2.8 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.2 1.2 GO:0030062 mitochondrial tricarboxylic acid cycle enzyme complex(GO:0030062)
0.2 4.2 GO:0031305 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.2 1.8 GO:0090543 Flemming body(GO:0090543)
0.2 2.9 GO:0032039 integrator complex(GO:0032039)
0.2 2.6 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.2 7.0 GO:0035145 exon-exon junction complex(GO:0035145)
0.2 1.5 GO:0042382 paraspeckles(GO:0042382)
0.2 14.3 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.2 0.6 GO:1990047 spindle matrix(GO:1990047)
0.2 2.0 GO:0043220 Schmidt-Lanterman incisure(GO:0043220)
0.2 1.3 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.2 17.1 GO:0000922 spindle pole(GO:0000922)
0.2 3.3 GO:0000242 pericentriolar material(GO:0000242)
0.2 6.2 GO:0015030 Cajal body(GO:0015030)
0.2 0.4 GO:0001739 sex chromatin(GO:0001739)
0.2 0.9 GO:1990130 Iml1 complex(GO:1990130)
0.2 0.5 GO:0070877 microprocessor complex(GO:0070877) ribonuclease III complex(GO:1903095)
0.2 3.1 GO:0045277 respiratory chain complex IV(GO:0045277)
0.2 3.4 GO:0035861 site of double-strand break(GO:0035861)
0.2 17.4 GO:0031526 brush border membrane(GO:0031526)
0.2 0.9 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.2 4.7 GO:0015935 small ribosomal subunit(GO:0015935)
0.2 4.7 GO:0072686 mitotic spindle(GO:0072686)
0.2 2.0 GO:0070938 contractile ring(GO:0070938)
0.2 1.4 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.2 0.9 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.2 1.4 GO:0030478 actin cap(GO:0030478)
0.1 0.6 GO:0031523 Myb complex(GO:0031523)
0.1 0.7 GO:0044530 supraspliceosomal complex(GO:0044530)
0.1 0.9 GO:0016461 unconventional myosin complex(GO:0016461)
0.1 0.4 GO:0031372 UBC13-MMS2 complex(GO:0031372)
0.1 17.6 GO:0000781 chromosome, telomeric region(GO:0000781)
0.1 4.2 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.1 2.5 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.1 6.0 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 1.5 GO:0071004 U2-type prespliceosome(GO:0071004)
0.1 0.9 GO:0033263 CORVET complex(GO:0033263)
0.1 0.6 GO:0000313 organellar ribosome(GO:0000313) mitochondrial ribosome(GO:0005761)
0.1 5.5 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.1 1.3 GO:0005682 U5 snRNP(GO:0005682)
0.1 1.6 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.1 5.1 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.1 2.0 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.1 2.7 GO:0032040 small-subunit processome(GO:0032040)
0.1 1.6 GO:0098800 inner mitochondrial membrane protein complex(GO:0098800)
0.1 1.8 GO:0097225 sperm midpiece(GO:0097225)
0.1 6.9 GO:0005819 spindle(GO:0005819)
0.1 0.7 GO:0031415 NatA complex(GO:0031415)
0.1 0.5 GO:0005968 Rab-protein geranylgeranyltransferase complex(GO:0005968)
0.1 0.3 GO:0031533 mRNA cap methyltransferase complex(GO:0031533)
0.1 1.6 GO:0005779 integral component of peroxisomal membrane(GO:0005779)
0.1 1.6 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.1 0.8 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 0.5 GO:0071256 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.1 0.7 GO:1990316 ATG1/ULK1 kinase complex(GO:1990316)
0.1 6.9 GO:0016328 lateral plasma membrane(GO:0016328)
0.1 2.4 GO:0002080 acrosomal membrane(GO:0002080)
0.1 0.2 GO:0033061 DNA recombinase mediator complex(GO:0033061)
0.1 0.2 GO:0031166 integral component of vacuolar membrane(GO:0031166) intrinsic component of vacuolar membrane(GO:0031310)
0.1 1.6 GO:0043196 varicosity(GO:0043196)
0.1 0.5 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.1 0.3 GO:0089701 U2AF(GO:0089701)
0.1 3.0 GO:0044295 axonal growth cone(GO:0044295)
0.1 0.5 GO:0071203 WASH complex(GO:0071203)
0.1 0.9 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.1 0.7 GO:0016272 prefoldin complex(GO:0016272)
0.1 0.5 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.1 0.3 GO:0032983 kainate selective glutamate receptor complex(GO:0032983)
0.1 0.1 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.1 5.5 GO:0005759 mitochondrial matrix(GO:0005759)
0.1 0.5 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 2.3 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.0 2.8 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 37.6 GO:0005730 nucleolus(GO:0005730)
0.0 1.2 GO:0016235 aggresome(GO:0016235)
0.0 0.1 GO:0044327 dendritic spine head(GO:0044327)
0.0 0.3 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.0 0.7 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.8 GO:0032279 asymmetric synapse(GO:0032279)
0.0 2.6 GO:0000776 kinetochore(GO:0000776)
0.0 8.4 GO:0031965 nuclear membrane(GO:0031965)
0.0 0.1 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 14.5 GO:0005813 centrosome(GO:0005813)
0.0 0.2 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 1.1 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.5 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.5 GO:0005839 proteasome core complex(GO:0005839)
0.0 2.4 GO:0000932 cytoplasmic mRNA processing body(GO:0000932)
0.0 2.4 GO:0005903 brush border(GO:0005903)
0.0 0.1 GO:0097543 ciliary inversin compartment(GO:0097543)
0.0 1.3 GO:0031672 A band(GO:0031672)
0.0 0.8 GO:0097610 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 37.4 GO:0005739 mitochondrion(GO:0005739)
0.0 0.3 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.3 GO:1990204 oxidoreductase complex(GO:1990204)
0.0 0.8 GO:0016592 mediator complex(GO:0016592)
0.0 0.4 GO:0098563 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.3 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.3 GO:0044665 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.0 GO:0097165 nuclear stress granule(GO:0097165)
0.0 0.7 GO:0031594 neuromuscular junction(GO:0031594)
0.0 0.4 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 1.9 GO:0008021 synaptic vesicle(GO:0008021)
0.0 0.1 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.6 GO:0032420 stereocilium(GO:0032420)
0.0 0.3 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 0.0 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.5 GO:0030315 T-tubule(GO:0030315)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
3.1 18.4 GO:0008518 reduced folate carrier activity(GO:0008518)
3.0 26.7 GO:0061676 importin-alpha family protein binding(GO:0061676)
2.4 16.5 GO:0048256 flap endonuclease activity(GO:0048256)
2.0 12.2 GO:0010997 anaphase-promoting complex binding(GO:0010997)
1.9 20.8 GO:0004526 ribonuclease P activity(GO:0004526)
1.6 11.2 GO:0000150 recombinase activity(GO:0000150)
1.6 8.0 GO:0044020 histone methyltransferase activity (H4-R3 specific)(GO:0044020)
1.4 5.7 GO:0000700 mismatch base pair DNA N-glycosylase activity(GO:0000700)
1.3 8.0 GO:0032027 myosin light chain binding(GO:0032027)
1.3 6.4 GO:0000702 oxidized base lesion DNA N-glycosylase activity(GO:0000702)
1.2 3.6 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179) rRNA (adenine-N6-)-methyltransferase activity(GO:0008988)
1.2 8.2 GO:0004468 lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468)
1.1 7.9 GO:0000403 Y-form DNA binding(GO:0000403)
1.1 10.1 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
1.1 5.3 GO:0030621 U4 snRNA binding(GO:0030621)
1.1 4.2 GO:0004832 valine-tRNA ligase activity(GO:0004832)
1.0 8.1 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
1.0 44.6 GO:0008536 Ran GTPase binding(GO:0008536)
1.0 13.5 GO:0003688 DNA replication origin binding(GO:0003688)
0.9 6.1 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.9 2.6 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.8 3.3 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.8 18.6 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.8 3.0 GO:0070883 pre-miRNA binding(GO:0070883)
0.7 3.0 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.7 2.2 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.7 2.1 GO:0017099 very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099)
0.7 10.2 GO:0001054 RNA polymerase I activity(GO:0001054)
0.7 5.3 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.6 3.8 GO:0035184 histone threonine kinase activity(GO:0035184)
0.6 3.0 GO:0032767 copper-dependent protein binding(GO:0032767)
0.6 4.1 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.6 2.3 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.6 14.8 GO:0097602 cullin family protein binding(GO:0097602)
0.6 6.1 GO:0036310 annealing helicase activity(GO:0036310)
0.5 4.3 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.5 9.0 GO:0051010 microtubule plus-end binding(GO:0051010)
0.5 2.1 GO:0003836 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836)
0.5 1.5 GO:0035827 rubidium ion transmembrane transporter activity(GO:0035827)
0.5 1.5 GO:0004140 dephospho-CoA kinase activity(GO:0004140)
0.5 5.4 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.5 8.1 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.5 3.3 GO:0015234 thiamine transmembrane transporter activity(GO:0015234)
0.5 0.9 GO:0030620 U2 snRNA binding(GO:0030620)
0.5 4.2 GO:0031419 cobalamin binding(GO:0031419)
0.5 4.6 GO:0008174 mRNA methyltransferase activity(GO:0008174)
0.4 7.2 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.4 1.7 GO:1990932 5.8S rRNA binding(GO:1990932)
0.4 6.9 GO:1990226 histone methyltransferase binding(GO:1990226)
0.4 10.9 GO:0008483 transaminase activity(GO:0008483)
0.4 9.2 GO:0008353 RNA polymerase II carboxy-terminal domain kinase activity(GO:0008353)
0.4 1.3 GO:0071209 histone pre-mRNA DCP binding(GO:0071208) U7 snRNA binding(GO:0071209)
0.4 1.2 GO:0004793 threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.4 0.8 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.4 2.7 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.4 3.8 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.4 12.0 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.4 1.8 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.4 2.5 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.4 3.5 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.4 2.8 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.3 1.7 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.3 2.1 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.3 1.3 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.3 3.3 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.3 2.1 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.3 8.8 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.3 0.9 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.3 1.1 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.3 2.0 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.3 2.5 GO:0008420 CTD phosphatase activity(GO:0008420)
0.3 1.6 GO:0008097 5S rRNA binding(GO:0008097)
0.3 1.8 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.3 1.0 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.3 6.2 GO:0032794 GTPase activating protein binding(GO:0032794)
0.3 2.1 GO:0031749 D2 dopamine receptor binding(GO:0031749)
0.3 40.6 GO:0003735 structural constituent of ribosome(GO:0003735)
0.2 13.9 GO:0003684 damaged DNA binding(GO:0003684)
0.2 2.4 GO:0003993 acid phosphatase activity(GO:0003993)
0.2 2.9 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.2 1.4 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.2 0.7 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.2 0.7 GO:0004774 succinate-CoA ligase activity(GO:0004774)
0.2 0.4 GO:0031493 nucleosomal histone binding(GO:0031493)
0.2 2.2 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.2 0.9 GO:0051880 G-quadruplex DNA binding(GO:0051880)
0.2 7.9 GO:0031369 translation initiation factor binding(GO:0031369)
0.2 1.2 GO:0042809 vitamin D receptor binding(GO:0042809)
0.2 1.4 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.2 2.4 GO:0000339 RNA cap binding(GO:0000339)
0.2 3.6 GO:0048038 quinone binding(GO:0048038)
0.2 6.5 GO:0000175 3'-5'-exoribonuclease activity(GO:0000175)
0.2 2.7 GO:0001163 RNA polymerase I regulatory region sequence-specific DNA binding(GO:0001163) RNA polymerase I CORE element sequence-specific DNA binding(GO:0001164)
0.2 8.8 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.2 1.9 GO:0015266 protein channel activity(GO:0015266)
0.2 4.5 GO:0031489 myosin V binding(GO:0031489)
0.2 13.7 GO:0048365 Rac GTPase binding(GO:0048365)
0.2 0.9 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.2 2.0 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.2 0.8 GO:0008061 chitin binding(GO:0008061)
0.2 1.1 GO:1990446 U1 snRNP binding(GO:1990446)
0.2 1.8 GO:0019213 deacetylase activity(GO:0019213)
0.2 1.5 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.2 4.1 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899)
0.2 4.1 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.1 1.5 GO:0050733 RS domain binding(GO:0050733)
0.1 5.3 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.1 0.8 GO:0004311 farnesyltranstransferase activity(GO:0004311)
0.1 1.7 GO:0000182 rDNA binding(GO:0000182)
0.1 0.8 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.1 4.8 GO:0001671 ATPase activator activity(GO:0001671)
0.1 0.3 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177) oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.1 6.8 GO:0051019 mitogen-activated protein kinase binding(GO:0051019)
0.1 2.8 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.1 0.5 GO:0032296 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.1 0.8 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1 0.9 GO:0061665 SUMO ligase activity(GO:0061665)
0.1 4.7 GO:0017091 AU-rich element binding(GO:0017091)
0.1 1.2 GO:0070034 telomerase RNA binding(GO:0070034)
0.1 0.5 GO:0008297 single-stranded DNA exodeoxyribonuclease activity(GO:0008297)
0.1 3.1 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.1 2.3 GO:0051400 BH domain binding(GO:0051400)
0.1 7.1 GO:0003730 mRNA 3'-UTR binding(GO:0003730)
0.1 2.3 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.1 1.7 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.1 0.2 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.1 0.4 GO:0016508 long-chain-enoyl-CoA hydratase activity(GO:0016508)
0.1 2.4 GO:0008327 methyl-CpG binding(GO:0008327)
0.1 1.0 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.1 1.7 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.1 0.9 GO:0043208 glycosphingolipid binding(GO:0043208)
0.1 3.3 GO:0043015 gamma-tubulin binding(GO:0043015)
0.1 7.5 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.1 0.7 GO:0017169 CDP-alcohol phosphatidyltransferase activity(GO:0017169)
0.1 2.0 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.1 0.3 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.1 14.0 GO:0016810 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds(GO:0016810)
0.1 3.6 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.1 1.7 GO:0004697 protein kinase C activity(GO:0004697)
0.1 0.8 GO:0005522 profilin binding(GO:0005522)
0.1 2.2 GO:0003697 single-stranded DNA binding(GO:0003697)
0.1 1.3 GO:0017160 Ral GTPase binding(GO:0017160)
0.1 1.2 GO:0046527 glucosyltransferase activity(GO:0046527)
0.1 0.9 GO:0010181 FMN binding(GO:0010181)
0.1 0.4 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.1 0.8 GO:0030955 potassium ion binding(GO:0030955)
0.1 0.4 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.1 1.0 GO:0015368 calcium:cation antiporter activity(GO:0015368)
0.1 1.1 GO:0017049 GTP-Rho binding(GO:0017049)
0.1 0.3 GO:0034235 GPI anchor binding(GO:0034235)
0.1 0.3 GO:0015277 kainate selective glutamate receptor activity(GO:0015277)
0.1 1.0 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.1 0.6 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.1 2.7 GO:0051879 Hsp90 protein binding(GO:0051879)
0.1 2.2 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.1 2.9 GO:0003743 translation initiation factor activity(GO:0003743)
0.1 0.2 GO:0097003 adipokinetic hormone receptor activity(GO:0097003)
0.1 0.5 GO:0008429 phosphatidylethanolamine binding(GO:0008429)
0.1 0.3 GO:0034190 apolipoprotein receptor binding(GO:0034190)
0.1 0.2 GO:0009041 uridylate kinase activity(GO:0009041)
0.1 0.1 GO:0032135 DNA insertion or deletion binding(GO:0032135)
0.1 8.1 GO:0004386 helicase activity(GO:0004386)
0.1 0.8 GO:0050811 GABA receptor binding(GO:0050811)
0.1 0.4 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.0 1.1 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.0 65.8 GO:0003723 RNA binding(GO:0003723)
0.0 0.1 GO:0000995 transcription factor activity, core RNA polymerase III binding(GO:0000995)
0.0 1.6 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 1.1 GO:0004385 guanylate kinase activity(GO:0004385)
0.0 0.4 GO:0031386 protein tag(GO:0031386)
0.0 1.0 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.3 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.0 0.3 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.3 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.5 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.0 2.5 GO:0016651 oxidoreductase activity, acting on NAD(P)H(GO:0016651)
0.0 2.1 GO:0070491 repressing transcription factor binding(GO:0070491)
0.0 1.3 GO:0008376 acetylgalactosaminyltransferase activity(GO:0008376)
0.0 0.8 GO:0032452 histone demethylase activity(GO:0032452)
0.0 0.1 GO:0030156 benzodiazepine receptor binding(GO:0030156)
0.0 0.4 GO:0060229 phospholipase activator activity(GO:0016004) lipase activator activity(GO:0060229)
0.0 0.5 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.0 0.3 GO:0004659 prenyltransferase activity(GO:0004659)
0.0 7.8 GO:0015631 tubulin binding(GO:0015631)
0.0 0.5 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 3.7 GO:0042393 histone binding(GO:0042393)
0.0 0.3 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 1.8 GO:0016879 ligase activity, forming carbon-nitrogen bonds(GO:0016879)
0.0 1.4 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.6 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 2.0 GO:0033613 activating transcription factor binding(GO:0033613)
0.0 0.2 GO:0015037 peptide disulfide oxidoreductase activity(GO:0015037)
0.0 0.3 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.0 0.1 GO:0015137 citrate transmembrane transporter activity(GO:0015137) tricarboxylic acid transmembrane transporter activity(GO:0015142)
0.0 2.3 GO:0005178 integrin binding(GO:0005178)
0.0 0.3 GO:0005234 extracellular-glutamate-gated ion channel activity(GO:0005234)
0.0 0.0 GO:0000033 alpha-1,3-mannosyltransferase activity(GO:0000033)
0.0 0.7 GO:0008307 structural constituent of muscle(GO:0008307)
0.0 0.4 GO:0102391 decanoate--CoA ligase activity(GO:0102391)
0.0 14.9 GO:0019904 protein domain specific binding(GO:0019904)
0.0 0.1 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.0 0.3 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 1.5 GO:0047485 protein N-terminus binding(GO:0047485)
0.0 0.1 GO:0019961 interferon binding(GO:0019961)
0.0 0.4 GO:0016701 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen(GO:0016701) oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 3.6 GO:0000287 magnesium ion binding(GO:0000287)
0.0 0.3 GO:0015026 coreceptor activity(GO:0015026)
0.0 0.5 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.2 GO:0005388 calcium-transporting ATPase activity(GO:0005388)
0.0 0.2 GO:0017025 TBP-class protein binding(GO:0017025)
0.0 0.5 GO:0050840 extracellular matrix binding(GO:0050840)
0.0 0.8 GO:0008565 protein transporter activity(GO:0008565)
0.0 0.1 GO:0008417 fucosyltransferase activity(GO:0008417)
0.0 3.0 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.1 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.0 1.0 GO:0004222 metalloendopeptidase activity(GO:0004222)
0.0 0.2 GO:0043175 RNA polymerase core enzyme binding(GO:0043175)
0.0 0.9 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 88.0 PID AURORA A PATHWAY Aurora A signaling
1.0 41.8 PID AURORA B PATHWAY Aurora B signaling
0.5 27.3 PID PLK1 PATHWAY PLK1 signaling events
0.4 6.5 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.3 7.2 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining
0.3 27.8 PID E2F PATHWAY E2F transcription factor network
0.3 7.9 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.3 10.8 PID BARD1 PATHWAY BARD1 signaling events
0.2 0.8 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events
0.1 5.6 ST GAQ PATHWAY G alpha q Pathway
0.1 2.7 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1 4.2 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.1 10.2 PID AR PATHWAY Coregulation of Androgen receptor activity
0.1 3.9 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1 3.3 PID FANCONI PATHWAY Fanconi anemia pathway
0.1 6.9 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.1 2.8 PID PI3KCI AKT PATHWAY Class I PI3K signaling events mediated by Akt
0.1 2.3 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.1 2.1 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.1 0.9 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.1 0.9 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.1 3.3 PID HNF3A PATHWAY FOXA1 transcription factor network
0.1 5.6 PID SMAD2 3NUCLEAR PATHWAY Regulation of nuclear SMAD2/3 signaling
0.1 2.2 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.1 3.1 PID INSULIN PATHWAY Insulin Pathway
0.1 5.1 PID CDC42 PATHWAY CDC42 signaling events
0.1 0.1 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.1 0.8 ST ADRENERGIC Adrenergic Pathway
0.1 2.9 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.1 3.7 PID P73PATHWAY p73 transcription factor network
0.1 2.6 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.1 0.8 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.1 1.8 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 1.0 ST B CELL ANTIGEN RECEPTOR B Cell Antigen Receptor
0.0 0.8 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.6 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.0 0.6 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 0.9 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 1.3 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 0.2 SIG CHEMOTAXIS Genes related to chemotaxis
0.0 0.6 SIG REGULATION OF THE ACTIN CYTOSKELETON BY RHO GTPASES Genes related to regulation of the actin cytoskeleton
0.0 0.7 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.3 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 1.3 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.5 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 0.6 PID BMP PATHWAY BMP receptor signaling
0.0 0.3 PID IL1 PATHWAY IL1-mediated signaling events
0.0 0.2 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.8 27.4 REACTOME PROCESSIVE SYNTHESIS ON THE LAGGING STRAND Genes involved in Processive synthesis on the lagging strand
1.3 18.4 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
1.2 25.1 REACTOME INHIBITION OF THE PROTEOLYTIC ACTIVITY OF APC C REQUIRED FOR THE ONSET OF ANAPHASE BY MITOTIC SPINDLE CHECKPOINT COMPONENTS Genes involved in Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
1.0 6.3 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
1.0 2.9 REACTOME APC C CDC20 MEDIATED DEGRADATION OF CYCLIN B Genes involved in APC/C:Cdc20 mediated degradation of Cyclin B
0.9 15.2 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.9 2.6 REACTOME PHOSPHORYLATION OF THE APC C Genes involved in Phosphorylation of the APC/C
0.9 22.2 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.9 0.9 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.8 8.1 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.8 20.4 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.7 7.9 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.7 70.6 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.6 11.0 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.6 2.4 REACTOME FORMATION OF THE HIV1 EARLY ELONGATION COMPLEX Genes involved in Formation of the HIV-1 Early Elongation Complex
0.5 9.6 REACTOME CRMPS IN SEMA3A SIGNALING Genes involved in CRMPs in Sema3A signaling
0.5 4.9 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.3 33.9 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.3 7.5 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.3 4.5 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.3 5.9 REACTOME KINESINS Genes involved in Kinesins
0.3 6.4 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.2 4.4 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.2 2.4 REACTOME ELONGATION ARREST AND RECOVERY Genes involved in Elongation arrest and recovery
0.2 4.8 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.2 3.4 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.2 14.7 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.2 11.4 REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
0.2 0.8 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.2 2.7 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.2 4.0 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.2 3.7 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.2 4.5 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.2 4.5 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.2 1.9 REACTOME P75NTR RECRUITS SIGNALLING COMPLEXES Genes involved in p75NTR recruits signalling complexes
0.2 2.2 REACTOME GAMMA CARBOXYLATION TRANSPORT AND AMINO TERMINAL CLEAVAGE OF PROTEINS Genes involved in Gamma-carboxylation, transport, and amino-terminal cleavage of proteins
0.2 2.6 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.1 0.3 REACTOME MRNA CAPPING Genes involved in mRNA Capping
0.1 9.4 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.1 1.2 REACTOME NUCLEAR SIGNALING BY ERBB4 Genes involved in Nuclear signaling by ERBB4
0.1 1.3 REACTOME HOST INTERACTIONS OF HIV FACTORS Genes involved in Host Interactions of HIV factors
0.1 3.5 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.1 1.0 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex
0.1 2.0 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.1 1.5 REACTOME ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S Genes involved in Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
0.1 2.4 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.1 0.7 REACTOME ORC1 REMOVAL FROM CHROMATIN Genes involved in Orc1 removal from chromatin
0.1 1.9 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.1 1.9 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.1 1.5 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.1 1.2 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.1 1.9 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.1 2.1 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.1 1.4 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.1 2.6 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.1 7.3 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production
0.1 2.6 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.1 1.3 REACTOME RNA POL III TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase III Transcription Termination
0.1 0.5 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 2 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 2 Promoter
0.1 0.5 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.1 1.7 REACTOME TRANSPORT OF MATURE TRANSCRIPT TO CYTOPLASM Genes involved in Transport of Mature Transcript to Cytoplasm
0.1 2.7 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.1 0.7 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.1 1.4 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.1 0.8 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.1 0.3 REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION Genes involved in Cyclin E associated events during G1/S transition
0.0 0.7 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.3 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.0 1.8 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.7 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.0 1.5 REACTOME RNA POL I TRANSCRIPTION Genes involved in RNA Polymerase I Transcription
0.0 0.9 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 1.5 REACTOME SIGNAL TRANSDUCTION BY L1 Genes involved in Signal transduction by L1
0.0 1.2 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 0.5 REACTOME NONSENSE MEDIATED DECAY ENHANCED BY THE EXON JUNCTION COMPLEX Genes involved in Nonsense Mediated Decay Enhanced by the Exon Junction Complex
0.0 1.0 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.8 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.9 REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0 0.9 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 0.4 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.9 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.0 1.1 REACTOME SYNTHESIS OF PA Genes involved in Synthesis of PA
0.0 1.5 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 2.1 REACTOME TRANSCRIPTIONAL REGULATION OF WHITE ADIPOCYTE DIFFERENTIATION Genes involved in Transcriptional Regulation of White Adipocyte Differentiation
0.0 0.5 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.3 REACTOME IONOTROPIC ACTIVITY OF KAINATE RECEPTORS Genes involved in Ionotropic activity of Kainate Receptors
0.0 0.4 REACTOME SYNTHESIS OF BILE ACIDS AND BILE SALTS VIA 7ALPHA HYDROXYCHOLESTEROL Genes involved in Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol
0.0 0.2 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 2.7 REACTOME POTASSIUM CHANNELS Genes involved in Potassium Channels
0.0 4.1 REACTOME SIGNALING BY RHO GTPASES Genes involved in Signaling by Rho GTPases
0.0 0.1 REACTOME SYNTHESIS OF PE Genes involved in Synthesis of PE
0.0 0.3 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 0.1 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0 0.5 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 1.0 REACTOME L1CAM INTERACTIONS Genes involved in L1CAM interactions
0.0 0.1 REACTOME TRANSCRIPTIONAL ACTIVITY OF SMAD2 SMAD3 SMAD4 HETEROTRIMER Genes involved in Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer
0.0 0.3 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 1.1 REACTOME APOPTOTIC EXECUTION PHASE Genes involved in Apoptotic execution phase
0.0 0.1 REACTOME DAG AND IP3 SIGNALING Genes involved in DAG and IP3 signaling
0.0 0.7 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 0.3 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions