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2D miR_HR1_12

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Results for Sox8

Z-value: 0.47

Motif logo

Transcription factors associated with Sox8

Gene Symbol Gene ID Gene Info
ENSMUSG00000024176.4 SRY (sex determining region Y)-box 8

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Sox8mm10_v2_chr17_-_25570678_25570694-0.303.4e-01Click!

Activity profile of Sox8 motif

Sorted Z-values of Sox8 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr5_+_90518932 0.54 ENSMUST00000113179.2
ENSMUST00000128740.1
afamin
chr11_+_69991633 0.52 ENSMUST00000108592.1
gamma-aminobutyric acid receptor associated protein
chr3_-_8667033 0.45 ENSMUST00000042412.3
hairy/enhancer-of-split related with YRPW motif 1
chr18_+_65698253 0.44 ENSMUST00000115097.1
ENSMUST00000117694.1
O-acyltransferase like
chr17_+_70561739 0.44 ENSMUST00000097288.2
discs, large (Drosophila) homolog-associated protein 1
chr11_+_69991061 0.32 ENSMUST00000018711.8
gamma-aminobutyric acid receptor associated protein
chr9_+_110052016 0.31 ENSMUST00000164930.1
ENSMUST00000163979.1
microtubule-associated protein 4
chr11_-_26591729 0.29 ENSMUST00000109504.1
vaccinia related kinase 2
chr15_-_99370427 0.28 ENSMUST00000081224.7
ENSMUST00000120633.1
ENSMUST00000088233.6
formin-like 3
chr3_+_65109343 0.27 ENSMUST00000159525.1
ENSMUST00000049230.8
potassium voltage-gated channel, shaker-related subfamily, beta member 1
chr18_+_36952621 0.26 ENSMUST00000115661.2
protocadherin alpha 2
chr7_-_126800036 0.26 ENSMUST00000133514.1
ENSMUST00000151137.1
aldolase A, fructose-bisphosphate
chr8_+_10006656 0.25 ENSMUST00000033892.7
tumor necrosis factor (ligand) superfamily, member 13b
chr10_+_82378593 0.25 ENSMUST00000165906.1
predicted gene 4924
chr10_-_34096507 0.23 ENSMUST00000069125.6
family with sequence similarity 26, member E
chr7_-_126800354 0.21 ENSMUST00000106348.1
aldolase A, fructose-bisphosphate
chr4_-_58553553 0.21 ENSMUST00000107575.2
ENSMUST00000107574.1
ENSMUST00000147354.1
lysophosphatidic acid receptor 1
chr1_+_135783065 0.21 ENSMUST00000132795.1
troponin I, skeletal, slow 1
chr4_+_124657646 0.21 ENSMUST00000053491.7
POU domain, class 3, transcription factor 1
chr2_-_84715160 0.19 ENSMUST00000035840.5
zinc finger, DHHC domain containing 5
chr2_+_69789647 0.18 ENSMUST00000112266.1
phosphatase, orphan 2
chr17_-_46327990 0.18 ENSMUST00000167360.1
ATP-binding cassette, sub-family C (CFTR/MRP), member 10
chr10_-_128180265 0.18 ENSMUST00000099139.1
RNA binding motif, single stranded interacting protein 2
chr11_+_113659283 0.17 ENSMUST00000137878.1
component of oligomeric golgi complex 1
chr2_+_69789621 0.17 ENSMUST00000151298.1
ENSMUST00000028494.2
phosphatase, orphan 2
chr1_+_109983737 0.17 ENSMUST00000172005.1
cadherin 7, type 2
chr17_-_46327949 0.17 ENSMUST00000047970.7
ATP-binding cassette, sub-family C (CFTR/MRP), member 10
chr4_+_154142363 0.17 ENSMUST00000030895.5
WD repeat containing, antisense to Trp73
chr11_-_99993992 0.16 ENSMUST00000105049.1
keratin associated protein 17-1
chr2_-_69789568 0.16 ENSMUST00000094942.3
coiled-coil domain containing 173
chr6_-_72380416 0.15 ENSMUST00000101285.3
ENSMUST00000074231.3
vesicle-associated membrane protein 5
chr4_-_129578535 0.14 ENSMUST00000052835.8
family with sequence similarity 167, member B
chr13_-_19395728 0.14 ENSMUST00000039694.7
STARD3 N-terminal like
chr11_-_110095974 0.13 ENSMUST00000100287.2
ATP-binding cassette, sub-family A (ABC1), member 8a
chr17_+_26715644 0.12 ENSMUST00000062519.7
ENSMUST00000144221.1
ENSMUST00000142539.1
ENSMUST00000151681.1
CREB3 regulatory factor
chr3_+_102010138 0.11 ENSMUST00000066187.4
nescient helix loop helix 2
chr1_+_109993982 0.11 ENSMUST00000027542.6
cadherin 7, type 2
chr2_+_4400958 0.10 ENSMUST00000075767.7
FERM domain containing 4A
chr6_+_129397297 0.10 ENSMUST00000032262.7
C-type lectin domain family 1, member b
chr11_-_99351086 0.10 ENSMUST00000017732.2
keratin 27
chr11_-_69758630 0.10 ENSMUST00000058470.9
polymerase (RNA) II (DNA directed) polypeptide A
chr9_-_95815389 0.08 ENSMUST00000119760.1
plastin 1 (I-isoform)
chr15_-_89149557 0.07 ENSMUST00000088823.3
mitogen-activated protein kinase 11
chr11_-_110095937 0.07 ENSMUST00000106664.3
ENSMUST00000046223.7
ENSMUST00000106662.1
ATP-binding cassette, sub-family A (ABC1), member 8a
chr11_+_97415527 0.06 ENSMUST00000121799.1
Rho GTPase activating protein 23
chrX_-_23285532 0.05 ENSMUST00000115319.2
kelch-like 13
chrX_-_162643575 0.04 ENSMUST00000101102.1
RALBP1 associated Eps domain containing protein 2
chr6_+_92869357 0.03 ENSMUST00000113434.1
predicted gene 15737
chr16_-_29541483 0.03 ENSMUST00000057018.8
ENSMUST00000182627.1
ATPase type 13A4
chr11_-_46166397 0.03 ENSMUST00000020679.2
NIPA-like domain containing 4
chr3_+_96104498 0.03 ENSMUST00000132980.1
ENSMUST00000138206.1
ENSMUST00000090785.2
ENSMUST00000035519.5
OTU domain containing 7B
chr19_-_41263931 0.03 ENSMUST00000025989.8
transmembrane 9 superfamily member 3
chr11_+_11487671 0.02 ENSMUST00000020410.4
RIKEN cDNA 4930415F15 gene
chr9_-_61976563 0.02 ENSMUST00000113990.1
progestin and adipoQ receptor family member V
chr8_+_34807287 0.02 ENSMUST00000033930.4
dual specificity phosphatase 4
chrX_-_162643629 0.02 ENSMUST00000112334.1
RALBP1 associated Eps domain containing protein 2
chr18_+_80046854 0.02 ENSMUST00000070219.7
par-6 partitioning defective 6 homolog gamma (C. elegans)
chr8_+_94745590 0.02 ENSMUST00000034231.3
chemokine (C-C motif) ligand 22
chr9_-_60838200 0.02 ENSMUST00000063858.7
predicted gene 9869
chr5_+_43515513 0.02 ENSMUST00000167522.1
ENSMUST00000144558.1
ENSMUST00000076939.6
C1q and tumor necrosis factor related protein 7
chr9_-_95858320 0.01 ENSMUST00000178038.1
RIKEN cDNA 1700065D16 gene
chrX_-_72918284 0.00 ENSMUST00000152200.1
centrin 2

Network of associatons between targets according to the STRING database.

First level regulatory network of Sox8

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:2000820 negative regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000820)
0.1 0.3 GO:0031296 B cell costimulation(GO:0031296)
0.1 0.8 GO:0006995 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.1 0.3 GO:0051012 microtubule sliding(GO:0051012)
0.1 0.2 GO:1904565 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.0 0.5 GO:0030388 fructose 1,6-bisphosphate metabolic process(GO:0030388)
0.0 0.4 GO:0070842 aggresome assembly(GO:0070842)
0.0 0.3 GO:2000659 regulation of interleukin-1-mediated signaling pathway(GO:2000659)
0.0 0.1 GO:1902896 terminal web assembly(GO:1902896)
0.0 0.1 GO:0038161 prolactin signaling pathway(GO:0038161) negative regulation of glucocorticoid mediated signaling pathway(GO:1900170)
0.0 0.2 GO:0014883 transition between fast and slow fiber(GO:0014883)
0.0 0.3 GO:1902260 negative regulation of delayed rectifier potassium channel activity(GO:1902260)
0.0 0.1 GO:2001184 positive regulation of interleukin-12 secretion(GO:2001184)
0.0 0.5 GO:0051180 vitamin transport(GO:0051180)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 GO:0097225 sperm midpiece(GO:0097225)
0.0 0.2 GO:0005861 troponin complex(GO:0005861)
0.0 0.5 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.3 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.2 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.1 GO:1990357 terminal web(GO:1990357)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0008431 vitamin E binding(GO:0008431)
0.2 0.5 GO:0035939 microsatellite binding(GO:0035939)
0.1 0.3 GO:0033883 pyridoxal phosphatase activity(GO:0033883)
0.1 0.5 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)
0.0 0.8 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.2 GO:0070915 lysophosphatidic acid receptor activity(GO:0070915)
0.0 0.3 GO:0070402 NADPH binding(GO:0070402)
0.0 0.3 GO:0032794 GTPase activating protein binding(GO:0032794)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 REACTOME GLYCOLYSIS Genes involved in Glycolysis