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2D miR_HR1_12

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Results for Batf

Z-value: 0.46

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Transcription factors associated with Batf

Gene Symbol Gene ID Gene Info
ENSMUSG00000034266.5 basic leucine zipper transcription factor, ATF-like

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Batfmm10_v2_chr12_+_85686648_856867020.019.8e-01Click!

Activity profile of Batf motif

Sorted Z-values of Batf motif

Promoter Log-likelihood Transcript Gene Gene Info
chr10_+_88091070 1.36 ENSMUST00000048621.7
pro-melanin-concentrating hormone
chr6_-_145047725 0.78 ENSMUST00000123930.1
branched chain aminotransferase 1, cytosolic
chr6_-_145047636 0.57 ENSMUST00000149769.1
branched chain aminotransferase 1, cytosolic
chr9_+_7272514 0.54 ENSMUST00000015394.8
matrix metallopeptidase 13
chr14_-_33185066 0.50 ENSMUST00000061753.8
ENSMUST00000130509.2
WD repeat and FYVE domain containing 4
chr1_-_74749221 0.50 ENSMUST00000081636.6
protein kinase, AMP-activated, gamma 3 non-catatlytic subunit
chr15_+_8109313 0.43 ENSMUST00000163765.1
nucleoporin 155
chr18_+_40258361 0.41 ENSMUST00000091927.4
potassium channel tetramerisation domain containing 16
chr5_+_8798139 0.40 ENSMUST00000009058.5
ATP-binding cassette, sub-family B (MDR/TAP), member 1B
chr5_-_114091358 0.36 ENSMUST00000150106.1
SV2 related protein
chr17_-_45592485 0.35 ENSMUST00000166119.1
solute carrier family 29 (nucleoside transporters), member 1
chr6_+_41538218 0.34 ENSMUST00000103291.1
T cell receptor beta, constant region 1
chr17_+_47769191 0.32 ENSMUST00000160373.1
ENSMUST00000159641.1
transcription factor EB
chr17_-_45592262 0.31 ENSMUST00000164769.1
solute carrier family 29 (nucleoside transporters), member 1
chr7_-_126369543 0.31 ENSMUST00000032997.6
linker for activation of T cells
chr11_+_82045705 0.30 ENSMUST00000021011.2
chemokine (C-C motif) ligand 7
chr5_-_149051604 0.29 ENSMUST00000093196.4
high mobility group box 1
chr3_+_133338936 0.28 ENSMUST00000150386.1
ENSMUST00000125858.1
pyrophosphatase (inorganic) 2
chr5_-_149051300 0.24 ENSMUST00000110505.1
high mobility group box 1
chr7_-_45211877 0.24 ENSMUST00000033057.7
dickkopf-like 1
chr3_+_138217814 0.22 ENSMUST00000090171.5
alcohol dehydrogenase 7 (class IV), mu or sigma polypeptide
chr1_-_171649002 0.21 ENSMUST00000111276.3
SLAM family member 7
chr1_+_181150926 0.21 ENSMUST00000134115.1
ENSMUST00000111059.1
cornichon homolog 4 (Drosophila)
chr3_+_14641722 0.20 ENSMUST00000029071.8
carbonic anhydrase 13
chr2_-_65529275 0.20 ENSMUST00000126837.1
sodium channel, voltage-gated, type III, alpha
chr4_-_59783800 0.19 ENSMUST00000107526.1
ENSMUST00000095063.4
INTS3 and NABP interacting protein
chr19_+_29410919 0.16 ENSMUST00000112576.2
programmed cell death 1 ligand 2
chr11_-_3914664 0.16 ENSMUST00000109995.1
ENSMUST00000051207.1
solute carrier family 35, member E4
chr15_+_103453782 0.15 ENSMUST00000047405.7
NCK associated protein 1 like
chr4_+_155869540 0.14 ENSMUST00000120794.1
ENSMUST00000030901.2
cleavage and polyadenylation specific factor 3-like
chr15_-_8710409 0.14 ENSMUST00000157065.1
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr2_-_74579379 0.14 ENSMUST00000130586.1
limb and neural patterns
chr7_+_118633729 0.13 ENSMUST00000057320.7
transmembrane channel-like gene family 5
chr2_-_45110241 0.12 ENSMUST00000177302.1
zinc finger E-box binding homeobox 2
chr13_-_60897439 0.12 ENSMUST00000171347.1
ENSMUST00000021884.8
cytotoxic T lymphocyte-associated protein 2 beta
chr12_+_83632208 0.11 ENSMUST00000048155.9
ENSMUST00000182618.1
ENSMUST00000183154.1
ENSMUST00000182036.1
ENSMUST00000182347.1
RNA binding motif protein 25
chr7_-_142661858 0.11 ENSMUST00000145896.2
insulin-like growth factor 2
chr2_-_74578875 0.11 ENSMUST00000134168.1
ENSMUST00000111993.2
ENSMUST00000064503.6
limb and neural patterns
chr5_+_137761680 0.10 ENSMUST00000110983.2
ENSMUST00000031738.4
TSC22 domain family, member 4
chr2_-_155514796 0.10 ENSMUST00000029131.4
gamma-glutamyltransferase 7
chr11_-_29825649 0.10 ENSMUST00000104962.1
RIKEN cDNA 4931440F15 gene
chr18_+_42275353 0.09 ENSMUST00000046972.7
ENSMUST00000091920.5
RNA binding motif protein 27
chr6_-_106745109 0.09 ENSMUST00000167925.2
interleukin 5 receptor, alpha
chr13_-_21780616 0.09 ENSMUST00000080511.2
histone cluster 1, H1b
chr11_-_79059872 0.09 ENSMUST00000141409.1
kinase suppressor of ras 1
chrX_+_151046131 0.08 ENSMUST00000112685.1
FYVE, RhoGEF and PH domain containing 1
chr4_+_58285930 0.06 ENSMUST00000081919.5
ENSMUST00000102893.3
ENSMUST00000084578.5
ENSMUST00000098057.3
ENSMUST00000179951.1
ENSMUST00000098059.3
ENSMUST00000177951.1
muscle, skeletal, receptor tyrosine kinase
chr16_+_18836573 0.05 ENSMUST00000055413.6
RIKEN cDNA 2510002D24 gene
chr19_-_11818806 0.05 ENSMUST00000075304.6
syntaxin 3
chr3_-_137552622 0.05 ENSMUST00000068546.5
predicted gene 4861
chr8_-_60954726 0.05 ENSMUST00000110302.1
chloride channel 3
chr6_-_122856151 0.05 ENSMUST00000042081.8
complement component 3a receptor 1
chr9_+_124121534 0.04 ENSMUST00000111442.1
ENSMUST00000171499.2
chemokine (C-C motif) receptor 5
chr7_+_116093296 0.04 ENSMUST00000032899.5
RIKEN cDNA 1110004F10 gene
chr1_+_165302625 0.04 ENSMUST00000111450.1
G protein-coupled receptor 161
chrX_+_133908441 0.03 ENSMUST00000113304.1
sushi-repeat-containing protein, X-linked 2
chr6_-_141946791 0.03 ENSMUST00000168119.1
solute carrier organic anion transporter family, member 1a1
chr10_+_128706251 0.03 ENSMUST00000054125.8
premelanosome protein
chr15_+_81744848 0.03 ENSMUST00000109554.1
zinc finger CCCH type containing 7B
chr7_+_116093336 0.03 ENSMUST00000106608.1
ENSMUST00000106607.1
RIKEN cDNA 1110004F10 gene
chr6_-_122282810 0.03 ENSMUST00000032207.8
killer cell lectin-like receptor subfamily G, member 1
chr17_-_24886304 0.02 ENSMUST00000044252.5
nucleotide binding protein 2
chr1_-_172590463 0.02 ENSMUST00000065679.6
SLAM family member 8
chr2_-_102400863 0.01 ENSMUST00000102573.1
tripartite motif-containing 44
chr6_-_141946960 0.01 ENSMUST00000042119.5
solute carrier organic anion transporter family, member 1a1
chr6_-_97459279 0.00 ENSMUST00000113359.1
FERM domain containing 4B
chr5_+_92376954 0.00 ENSMUST00000120781.1
ADP-ribosyltransferase 3
chr2_+_13573927 0.00 ENSMUST00000141365.1
ENSMUST00000028062.2
vimentin

Network of associatons between targets according to the STRING database.

First level regulatory network of Batf

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0046005 positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
0.2 1.3 GO:0009082 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.2 0.5 GO:0002270 plasmacytoid dendritic cell activation(GO:0002270) positive regulation of glycogen catabolic process(GO:0045819)
0.1 0.4 GO:0036228 protein targeting to nuclear inner membrane(GO:0036228)
0.1 0.5 GO:0090187 positive regulation of pancreatic juice secretion(GO:0090187)
0.1 0.7 GO:0015862 uridine transport(GO:0015862)
0.1 0.3 GO:0009816 defense response to bacterium, incompatible interaction(GO:0009816) regulation of defense response to bacterium, incompatible interaction(GO:1902477)
0.1 0.4 GO:0014045 establishment of endothelial blood-brain barrier(GO:0014045)
0.1 0.2 GO:0006069 ethanol oxidation(GO:0006069)
0.0 0.2 GO:0046684 response to pyrethroid(GO:0046684)
0.0 0.1 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376) actin polymerization-dependent cell motility(GO:0070358)
0.0 0.1 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.0 0.3 GO:0071361 cellular response to ethanol(GO:0071361)
0.0 0.1 GO:1902748 mammillary body development(GO:0021767) mammillary axonal complex development(GO:0061373) positive regulation of lens fiber cell differentiation(GO:1902748)
0.0 0.3 GO:0006968 cellular defense response(GO:0006968)
0.0 0.2 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.0 GO:0097401 synaptic vesicle lumen acidification(GO:0097401)
0.0 0.1 GO:1904395 positive regulation of skeletal muscle acetylcholine-gated channel clustering(GO:1904395)
0.0 0.1 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0 0.3 GO:0006910 phagocytosis, recognition(GO:0006910)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0044611 nuclear pore inner ring(GO:0044611)
0.1 0.9 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.2 GO:0070876 SOSS complex(GO:0070876)
0.0 0.3 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.0 0.5 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.1 GO:0031209 SCAR complex(GO:0031209)
0.0 0.2 GO:0001518 voltage-gated sodium channel complex(GO:0001518)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.3 GO:0004084 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.2 0.5 GO:0000401 open form four-way junction DNA binding(GO:0000401) crossed form four-way junction DNA binding(GO:0000402)
0.1 0.3 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.1 0.2 GO:0004024 alcohol dehydrogenase activity, zinc-dependent(GO:0004024)
0.1 0.3 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.1 0.4 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.0 1.4 GO:0071855 neuropeptide receptor binding(GO:0071855)
0.0 0.5 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.0 0.1 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.7 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.0 0.2 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.0 0.3 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.4 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.5 GO:0050750 low-density lipoprotein particle receptor binding(GO:0050750)
0.0 0.0 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.0 0.2 GO:0004089 carbonate dehydratase activity(GO:0004089)
0.0 0.1 GO:0036374 glutathione hydrolase activity(GO:0036374)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.5 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.5 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.6 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.2 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.5 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.2 REACTOME PD1 SIGNALING Genes involved in PD-1 signaling
0.0 0.7 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.4 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0 0.3 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.3 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.3 REACTOME GENERATION OF SECOND MESSENGER MOLECULES Genes involved in Generation of second messenger molecules
0.0 0.0 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion