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2D miR_HR1_12

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Results for Zic2

Z-value: 0.98

Motif logo

Transcription factors associated with Zic2

Gene Symbol Gene ID Gene Info
ENSMUSG00000061524.8 zinc finger protein of the cerebellum 2

Activity profile of Zic2 motif

Sorted Z-values of Zic2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr2_-_93452679 1.37 ENSMUST00000111257.1
ENSMUST00000145553.1
CD82 antigen
chr5_+_137288273 1.09 ENSMUST00000024099.4
ENSMUST00000085934.3
acetylcholinesterase
chr4_-_106800249 1.00 ENSMUST00000148688.1
acyl-CoA thioesterase 11
chr19_+_52264323 0.83 ENSMUST00000039652.4
insulin I
chr7_-_44816586 0.81 ENSMUST00000047356.8
activating transcription factor 5
chr19_+_58728887 0.81 ENSMUST00000048644.5
pancreatic lipase related protein 1
chr3_-_129332713 0.80 ENSMUST00000029658.7
glutamyl aminopeptidase
chr14_+_55853997 0.79 ENSMUST00000100529.3
NYN domain and retroviral integrase containing
chr3_-_59262825 0.79 ENSMUST00000050360.7
purinergic receptor P2Y, G-protein coupled 12
chrX_+_170009659 0.78 ENSMUST00000179760.1
predicted gene, 21887
chr8_+_95320440 0.76 ENSMUST00000162294.1
testis, prostate and placenta expressed
chr16_+_32756336 0.73 ENSMUST00000135753.1
mucin 4
chr12_-_104865076 0.71 ENSMUST00000109937.1
ENSMUST00000109936.1
calmin
chr15_-_75567176 0.70 ENSMUST00000156032.1
ENSMUST00000127095.1
lymphocyte antigen 6 complex, locus H
chr14_-_34374617 0.70 ENSMUST00000023826.4
synuclein, gamma
chr9_+_54538984 0.69 ENSMUST00000060242.5
ENSMUST00000118413.1
SH2 domain containing 7
chr5_+_108694222 0.69 ENSMUST00000013633.8
ENSMUST00000112560.3
fibroblast growth factor receptor-like 1
chr5_+_150952607 0.68 ENSMUST00000078856.6
klotho
chr11_+_99041237 0.67 ENSMUST00000017637.6
insulin-like growth factor binding protein 4
chr4_+_45012830 0.67 ENSMUST00000095105.1
RIKEN cDNA 1700055D18 gene
chr7_-_46179929 0.66 ENSMUST00000033123.6
ATP-binding cassette, sub-family C (CFTR/MRP), member 8
chr7_-_19699008 0.66 ENSMUST00000174355.1
ENSMUST00000172983.1
ENSMUST00000174710.1
ENSMUST00000167646.2
ENSMUST00000003066.9
ENSMUST00000174064.1
apolipoprotein E
chr4_-_134704235 0.65 ENSMUST00000054096.6
ENSMUST00000038628.3
mannosidase, alpha, class 1C, member 1
chr11_+_96929260 0.63 ENSMUST00000054311.5
ENSMUST00000107636.3
proline rich 15-like
chr7_+_121865070 0.61 ENSMUST00000033161.5
sodium channel, nonvoltage-gated 1 beta
chr11_-_106160708 0.60 ENSMUST00000106875.1
LIM domain containing 2
chr10_+_69151427 0.60 ENSMUST00000167286.1
Rho-related BTB domain containing 1
chr5_+_52363925 0.60 ENSMUST00000101208.4
superoxide dismutase 3, extracellular
chr14_-_26170283 0.60 ENSMUST00000100809.4
placenta specific 9b
chr16_-_16869255 0.59 ENSMUST00000075017.4
pre-B lymphocyte gene 1
chr11_+_96929367 0.58 ENSMUST00000062172.5
proline rich 15-like
chr6_-_124464772 0.57 ENSMUST00000008297.4
calsyntenin 3
chr7_-_142679533 0.56 ENSMUST00000162317.1
ENSMUST00000125933.1
ENSMUST00000105931.1
ENSMUST00000105930.1
ENSMUST00000105933.1
ENSMUST00000105932.1
ENSMUST00000000220.2
insulin II
chr4_+_40920047 0.55 ENSMUST00000030122.4
serine peptidase inhibitor, Kazal type 4
chr14_+_55854115 0.55 ENSMUST00000168479.1
NYN domain and retroviral integrase containing
chr8_+_109990430 0.55 ENSMUST00000001720.7
ENSMUST00000143741.1
tyrosine aminotransferase
chr1_-_125912160 0.54 ENSMUST00000159417.1
Ly6/Plaur domain containing 1
chr4_-_143299498 0.54 ENSMUST00000030317.7
podoplanin
chr11_+_4031770 0.53 ENSMUST00000019512.7
SEC14-like 4 (S. cerevisiae)
chr15_-_75566608 0.53 ENSMUST00000163116.1
ENSMUST00000023241.5
lymphocyte antigen 6 complex, locus H
chr4_-_140581774 0.52 ENSMUST00000147426.1
ENSMUST00000105797.2
Rho guanine nucleotide exchange factor (GEF) 10-like
chr15_+_102102926 0.51 ENSMUST00000169627.1
ENSMUST00000046144.9
tensin like C1 domain-containing phosphatase
chr11_+_43528759 0.51 ENSMUST00000050574.6
cyclin J-like
chr10_+_76253848 0.51 ENSMUST00000036387.7
S100 protein, beta polypeptide, neural
chr7_-_30924169 0.50 ENSMUST00000074671.6
hepcidin antimicrobial peptide 2
chr14_+_54464141 0.49 ENSMUST00000022782.8
low-density lipoprotein receptor-related protein 10
chr7_+_123462274 0.49 ENSMUST00000033023.3
aquaporin 8
chr2_+_150786735 0.49 ENSMUST00000045441.7
brain glycogen phosphorylase
chr4_-_143299463 0.49 ENSMUST00000119654.1
podoplanin
chr14_+_123659971 0.49 ENSMUST00000049681.7
integrin, beta-like 1
chr4_+_141239499 0.48 ENSMUST00000141834.2
Rho guanine nucleotide exchange factor (GEF) 19
chr15_-_75566811 0.48 ENSMUST00000065417.8
lymphocyte antigen 6 complex, locus H
chr10_+_127048235 0.47 ENSMUST00000165764.1
cytochrome P450, family 27, subfamily b, polypeptide 1
chr2_-_165090739 0.47 ENSMUST00000109304.1
RIKEN cDNA 1700025C18 gene
chr11_+_53457184 0.47 ENSMUST00000109013.2
shroom family member 1
chr11_-_96747419 0.47 ENSMUST00000181758.1
RIKEN cDNA 2010300F17 gene
chr7_-_79842287 0.47 ENSMUST00000049004.6
alanyl (membrane) aminopeptidase
chrX_+_49463926 0.47 ENSMUST00000130558.1
Rho GTPase activating protein 36
chr15_-_75841907 0.46 ENSMUST00000100538.2
zinc finger CCCH type containing 3
chr5_+_29195983 0.46 ENSMUST00000160888.1
ENSMUST00000159272.1
ENSMUST00000001247.5
ENSMUST00000161398.1
ENSMUST00000160246.1
ring finger protein 32
chr8_+_92827273 0.46 ENSMUST00000034187.7
matrix metallopeptidase 2
chr8_-_93197799 0.46 ENSMUST00000034172.7
carboxylesterase 1D
chr7_-_19698383 0.46 ENSMUST00000173739.1
apolipoprotein E
chr2_+_163122605 0.45 ENSMUST00000144092.1
predicted gene 11454
chr7_-_101868667 0.45 ENSMUST00000150184.1
folate receptor 1 (adult)
chr5_-_24351604 0.45 ENSMUST00000036092.7
potassium voltage-gated channel, subfamily H (eag-related), member 2
chr14_+_30715599 0.45 ENSMUST00000054230.4
Scm-like with four mbt domains 1
chr9_+_103112072 0.45 ENSMUST00000035155.6
RAB6B, member RAS oncogene family
chr10_-_81600857 0.44 ENSMUST00000151858.1
ENSMUST00000142948.1
ENSMUST00000072020.2
transducin-like enhancer of split 6, homolog of Drosophila E(spl)
chr4_+_43632185 0.44 ENSMUST00000107874.2
natriuretic peptide receptor 2
chr7_-_19698206 0.44 ENSMUST00000172808.1
ENSMUST00000174191.1
apolipoprotein E
chr1_-_170589791 0.43 ENSMUST00000161966.1
ENSMUST00000160456.1
nitric oxide synthase 1 (neuronal) adaptor protein
chr16_+_4639941 0.43 ENSMUST00000038770.3
vasorin
chr10_+_79890853 0.43 ENSMUST00000061653.7
complement factor D (adipsin)
chr16_-_10313940 0.42 ENSMUST00000078357.4
epithelial membrane protein 2
chr3_-_153725062 0.42 ENSMUST00000064460.5
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3
chrX_+_136666375 0.42 ENSMUST00000060904.4
ENSMUST00000113100.1
ENSMUST00000128040.1
transcription elongation factor A (SII)-like 3
chr19_-_6996025 0.42 ENSMUST00000041686.3
ENSMUST00000180765.1
nudix (nucleoside diphosphate linked moiety X)-type motif 22
chr17_+_69969387 0.42 ENSMUST00000146730.1
discs, large (Drosophila) homolog-associated protein 1
chr11_-_100414829 0.41 ENSMUST00000066489.6
leprecan-like 4
chr11_-_79146407 0.41 ENSMUST00000018478.4
ENSMUST00000108264.1
kinase suppressor of ras 1
chr17_-_25433775 0.40 ENSMUST00000159610.1
ENSMUST00000159048.1
ENSMUST00000078496.5
calcium channel, voltage-dependent, T type, alpha 1H subunit
chr4_-_141846277 0.40 ENSMUST00000105781.1
chymotrypsin C (caldecrin)
chr11_+_53457273 0.40 ENSMUST00000093114.4
shroom family member 1
chr2_-_172043466 0.39 ENSMUST00000087950.3
cerebellin 4 precursor protein
chr9_+_120577346 0.39 ENSMUST00000064646.4
RIKEN cDNA 5830454E08 gene
chr16_-_97611072 0.39 ENSMUST00000000395.6
transmembrane protease, serine 2
chr7_+_27692502 0.39 ENSMUST00000076421.6
RIKEN cDNA C030039L03 gene
chr11_-_29515017 0.39 ENSMUST00000133103.1
ENSMUST00000039900.3
prolyl-tRNA synthetase domain containing 1
chr5_-_139814231 0.39 ENSMUST00000044002.4
transmembrane protein 184a
chr3_-_83841767 0.38 ENSMUST00000029623.9
toll-like receptor 2
chr11_+_5861886 0.38 ENSMUST00000102923.3
AE binding protein 1
chr2_+_106695594 0.38 ENSMUST00000016530.7
metallophosphoesterase domain containing 2
chr11_+_113649169 0.38 ENSMUST00000018805.8
component of oligomeric golgi complex 1
chr15_+_98708187 0.38 ENSMUST00000003444.4
coiled-coil domain containing 65
chr9_+_104002546 0.37 ENSMUST00000035167.8
ENSMUST00000117054.1
nephronophthisis 3 (adolescent)
chr5_+_140607334 0.37 ENSMUST00000031555.1
LFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr13_-_62888282 0.37 ENSMUST00000092888.4
fructose bisphosphatase 1
chr6_+_119236507 0.37 ENSMUST00000037434.6
calcium channel, voltage-dependent, alpha 2/delta subunit 4
chr11_+_87578384 0.37 ENSMUST00000107962.1
ENSMUST00000122067.1
septin 4
chr11_-_60220550 0.37 ENSMUST00000020846.1
sterol regulatory element binding transcription factor 1
chr13_+_58806564 0.37 ENSMUST00000109838.2
neurotrophic tyrosine kinase, receptor, type 2
chr2_+_92915080 0.37 ENSMUST00000028648.2
synaptotagmin XIII
chr17_+_24352037 0.36 ENSMUST00000079594.5
ATP-binding cassette, sub-family A (ABC1), member 3
chr8_-_105933832 0.36 ENSMUST00000034368.6
chymotrypsin-like
chr2_-_150904620 0.36 ENSMUST00000056149.8
abhydrolase domain containing 12
chr17_+_33919332 0.36 ENSMUST00000025161.7
TAP binding protein
chrX_+_151520655 0.36 ENSMUST00000112666.1
ENSMUST00000168501.1
ENSMUST00000112662.2
PHD finger protein 8
chr19_+_6996114 0.36 ENSMUST00000088223.5
tRNA phosphotransferase 1
chr4_-_96591555 0.35 ENSMUST00000055693.8
cytochrome P450, family 2, subfamily j, polypeptide 9
chr7_-_44997535 0.35 ENSMUST00000124232.1
ENSMUST00000003290.4
BCL2-like 12 (proline rich)
chr17_-_91088726 0.35 ENSMUST00000072671.7
ENSMUST00000174331.1
ENSMUST00000161402.3
ENSMUST00000054059.8
neurexin I
chr18_+_37742088 0.35 ENSMUST00000003599.6
protocadherin gamma subfamily A, 9
chr11_-_106487833 0.35 ENSMUST00000106801.1
endoplasmic reticulum (ER) to nucleus signalling 1
chr9_+_88581036 0.34 ENSMUST00000164661.2
tripartite motif-containing 43A
chr14_+_41131777 0.34 ENSMUST00000022314.3
ENSMUST00000170719.1
surfactant associated protein A1
chr11_-_73324616 0.34 ENSMUST00000021119.2
aspartoacylase
chr1_+_88055377 0.34 ENSMUST00000138182.1
ENSMUST00000113142.3
UDP glycosyltransferase 1 family, polypeptide A10
chr3_+_32817520 0.34 ENSMUST00000072312.5
ENSMUST00000108228.1
ubiquitin specific peptidase 13 (isopeptidase T-3)
chr16_+_17331371 0.34 ENSMUST00000023450.6
ENSMUST00000161034.1
serine (or cysteine) peptidase inhibitor, clade D, member 1
chr7_-_141214080 0.34 ENSMUST00000026573.5
ENSMUST00000170841.1
RIKEN cDNA 1600016N20 gene
chr4_+_106622424 0.34 ENSMUST00000047922.2
tetratricopeptide repeat domain 22
chr11_+_121702591 0.33 ENSMUST00000125580.1
meteorin, glial cell differentiation regulator-like
chr15_+_54952939 0.33 ENSMUST00000181704.1
predicted gene, 26684
chr19_-_6235804 0.33 ENSMUST00000025695.9
protein phosphatase 2, regulatory subunit B (B56), beta isoform
chr11_-_117779605 0.32 ENSMUST00000143406.1
transmembrane channel-like gene family 6
chr9_-_20728219 0.32 ENSMUST00000034692.7
olfactomedin 2
chr19_+_46573362 0.32 ENSMUST00000026011.6
sideroflexin 2
chr6_+_36388055 0.32 ENSMUST00000172278.1
cholinergic receptor, muscarinic 2, cardiac
chr11_+_113649328 0.32 ENSMUST00000063776.7
component of oligomeric golgi complex 1
chrX_+_170009892 0.31 ENSMUST00000180251.1
predicted gene, 21887
chr17_-_28486082 0.31 ENSMUST00000079413.3
FK506 binding protein 5
chr4_-_45012287 0.31 ENSMUST00000055028.8
ENSMUST00000180217.1
ENSMUST00000107817.2
zinc finger and BTB domain containing 5
chr9_+_58554799 0.30 ENSMUST00000098676.2
predicted gene 10657
chr11_+_105292637 0.30 ENSMUST00000100335.3
ENSMUST00000021038.4
mannose receptor, C type 2
chr10_-_25297055 0.30 ENSMUST00000177124.1
A kinase (PRKA) anchor protein 7
chr11_-_119355484 0.29 ENSMUST00000100172.2
ENSMUST00000005173.4
N-sulfoglucosamine sulfohydrolase (sulfamidase)
chr11_+_53457209 0.29 ENSMUST00000018531.5
shroom family member 1
chr5_+_139423151 0.29 ENSMUST00000066211.4
G protein-coupled estrogen receptor 1
chr11_+_121434913 0.29 ENSMUST00000026175.2
ENSMUST00000092302.4
ENSMUST00000103014.3
fructosamine 3 kinase
chr18_-_24709348 0.29 ENSMUST00000067987.1
predicted gene 9955
chr7_+_30776394 0.29 ENSMUST00000041703.7
dermokine
chr2_-_153529941 0.29 ENSMUST00000035346.7
RIKEN cDNA 8430427H17 gene
chr13_-_90089556 0.29 ENSMUST00000022115.7
X-ray repair complementing defective repair in Chinese hamster cells 4
chr2_-_66634952 0.29 ENSMUST00000100064.2
ENSMUST00000100063.2
sodium channel, voltage-gated, type IX, alpha
chr10_+_119992916 0.28 ENSMUST00000105261.2
glutamate receptor interacting protein 1
chr11_+_78536355 0.28 ENSMUST00000128788.1
intraflagellar transport 20
chr8_-_93229517 0.28 ENSMUST00000176282.1
ENSMUST00000034173.7
carboxylesterase 1E
chr19_+_45047557 0.28 ENSMUST00000062213.5
ENSMUST00000111954.4
ENSMUST00000084493.6
sideroflexin 3
chr8_+_34154563 0.28 ENSMUST00000033933.5
transmembrane protein 66
chr5_+_105824511 0.28 ENSMUST00000055994.3
RIKEN cDNA D830014E11 gene
chr2_-_38287347 0.28 ENSMUST00000102787.3
DENN/MADD domain containing 1A
chr3_+_157566868 0.28 ENSMUST00000041175.6
ENSMUST00000173533.1
prostaglandin E receptor 3 (subtype EP3)
chr1_-_36244245 0.28 ENSMUST00000046875.7
UDP-glucose glycoprotein glucosyltransferase 1
chr7_-_45666292 0.28 ENSMUST00000069800.4
fucosyltransferase 2
chr4_-_43669141 0.27 ENSMUST00000056474.6
family with sequence similarity 221, member B
chr17_-_24209377 0.27 ENSMUST00000024931.4
netrin 3
chr1_-_13127163 0.27 ENSMUST00000047577.6
PR domain containing 14
chr11_+_117115195 0.27 ENSMUST00000103026.3
ENSMUST00000090433.5
SEC14-like 1 (S. cerevisiae)
chr5_+_141856692 0.27 ENSMUST00000074546.6
sidekick homolog 1 (chicken)
chr13_+_47122719 0.27 ENSMUST00000068891.4
ring finger protein 144B
chr2_+_170731807 0.27 ENSMUST00000029075.4
docking protein 5
chr4_+_20042046 0.27 ENSMUST00000098242.3
gamma-glutamyl hydrolase
chr7_+_35119285 0.27 ENSMUST00000042985.9
CCAAT/enhancer binding protein (C/EBP), alpha
chr12_-_104998677 0.27 ENSMUST00000095439.3
ENSMUST00000109927.1
spectrin repeat containing, nuclear envelope family member 3
chr10_-_53699343 0.27 ENSMUST00000163761.1
family with sequence similarity 184, member A
chr8_+_13287887 0.27 ENSMUST00000045229.5
transmembrane and coiled-coil domains 3
chr9_+_107400043 0.27 ENSMUST00000166799.1
ENSMUST00000170737.1
calcium channel, voltage-dependent, alpha 2/delta subunit 2
chr4_+_137913471 0.26 ENSMUST00000151110.1
endothelin converting enzyme 1
chr11_-_96747405 0.26 ENSMUST00000180492.1
RIKEN cDNA 2010300F17 gene
chr1_+_88055467 0.26 ENSMUST00000173325.1
UDP glycosyltransferase 1 family, polypeptide A10
chr3_+_31902666 0.26 ENSMUST00000119970.1
ENSMUST00000178668.1
potassium large conductance calcium-activated channel, subfamily M, beta member 2
chr9_-_108567336 0.26 ENSMUST00000074208.4
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 3
chr4_-_4138817 0.26 ENSMUST00000133567.1
preproenkephalin
chr19_-_38124801 0.26 ENSMUST00000112335.2
retinol binding protein 4, plasma
chr7_-_134938264 0.25 ENSMUST00000171394.1
family with sequence similarity 196, member A
chr11_+_63128973 0.25 ENSMUST00000108702.1
peripheral myelin protein 22
chr4_+_43631935 0.25 ENSMUST00000030191.8
natriuretic peptide receptor 2
chr1_-_136953600 0.25 ENSMUST00000168126.1
nuclear receptor subfamily 5, group A, member 2
chr14_+_27039001 0.25 ENSMUST00000035336.3
interleukin 17 receptor D
chr6_-_41314700 0.25 ENSMUST00000064324.5
trypsin 5
chr8_+_121590361 0.25 ENSMUST00000034270.10
ENSMUST00000181948.1
microtubule-associated protein 1 light chain 3 beta
chr12_-_113422730 0.25 ENSMUST00000177715.1
ENSMUST00000103426.1
immunoglobulin heavy constant mu
chr6_-_72617000 0.25 ENSMUST00000070524.4
trans-golgi network protein
chr6_-_31563978 0.24 ENSMUST00000026698.7
podocalyxin-like
chr7_-_25297967 0.24 ENSMUST00000005583.5
platelet-activating factor acetylhydrolase, isoform 1b, subunit 3
chr12_+_104214538 0.24 ENSMUST00000121337.1
ENSMUST00000167049.1
ENSMUST00000101080.1
serine (or cysteine) peptidase inhibitor, clade A, member 3F
chr4_-_58987095 0.24 ENSMUST00000030069.6
prostaglandin reductase 1
chr4_-_126163470 0.24 ENSMUST00000097891.3
SH3 domain containing 21
chr7_-_142666816 0.24 ENSMUST00000105935.1
insulin-like growth factor 2
chr17_-_46752170 0.24 ENSMUST00000121671.1
ENSMUST00000059844.6
canopy 3 homolog (zebrafish)
chr16_-_20621255 0.24 ENSMUST00000052939.2
calcium/calmodulin-dependent protein kinase II inhibitor 2
chr4_+_43669266 0.24 ENSMUST00000107864.1
transmembrane protein 8B
chr6_+_8259288 0.24 ENSMUST00000159335.1
predicted gene 16039
chr12_-_108702265 0.24 ENSMUST00000167978.1
ENSMUST00000021691.4
degenerative spermatocyte homolog 2 (Drosophila), lipid desaturase
chr11_+_78536393 0.23 ENSMUST00000050366.8
ENSMUST00000108275.1
intraflagellar transport 20
chr17_-_12909912 0.23 ENSMUST00000163394.1
poly(A)-specific ribonuclease (PARN)-like domain containing 1
chr2_-_66634653 0.23 ENSMUST00000164384.2
ENSMUST00000169900.1
sodium channel, voltage-gated, type IX, alpha
chr9_-_60838200 0.23 ENSMUST00000063858.7
predicted gene 9869
chr14_-_32465909 0.23 ENSMUST00000070125.4
choline acetyltransferase

Network of associatons between targets according to the STRING database.

First level regulatory network of Zic2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:1903000 regulation of lipid transport across blood brain barrier(GO:1903000) positive regulation of lipid transport across blood brain barrier(GO:1903002)
0.4 1.3 GO:1904328 regulation of myofibroblast contraction(GO:1904328) myofibroblast contraction(GO:1990764)
0.3 1.3 GO:1900619 acetylcholine metabolic process(GO:0008291) acetate ester metabolic process(GO:1900619)
0.2 0.7 GO:1901079 positive regulation of relaxation of muscle(GO:1901079)
0.2 0.8 GO:1904139 microglial cell migration(GO:1904124) regulation of microglial cell migration(GO:1904139)
0.2 0.6 GO:1990535 negative regulation of NAD(P)H oxidase activity(GO:0033861) neuron projection maintenance(GO:1990535)
0.2 0.6 GO:0035574 histone H4-K20 demethylation(GO:0035574)
0.2 1.3 GO:0015074 DNA integration(GO:0015074)
0.2 0.8 GO:0002003 angiotensin maturation(GO:0002003)
0.2 0.5 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
0.1 0.4 GO:2000170 positive regulation of peptidyl-cysteine S-nitrosylation(GO:2000170)
0.1 0.5 GO:0006572 tyrosine catabolic process(GO:0006572)
0.1 0.4 GO:0051385 response to mineralocorticoid(GO:0051385)
0.1 0.4 GO:0071725 cell surface pattern recognition receptor signaling pathway(GO:0002752) positive regulation of interleukin-18 production(GO:0032741) response to immune response of other organism involved in symbiotic interaction(GO:0052564) response to host immune response(GO:0052572) detection of bacterial lipopeptide(GO:0070340) response to triacyl bacterial lipopeptide(GO:0071725) cellular response to triacyl bacterial lipopeptide(GO:0071727)
0.1 0.5 GO:0034760 negative regulation of iron ion transport(GO:0034757) negative regulation of iron ion transmembrane transport(GO:0034760)
0.1 0.4 GO:0046351 disaccharide biosynthetic process(GO:0046351)
0.1 0.7 GO:0002838 negative regulation of response to tumor cell(GO:0002835) negative regulation of immune response to tumor cell(GO:0002838)
0.1 0.4 GO:0046462 monoacylglycerol metabolic process(GO:0046462)
0.1 0.5 GO:1901421 positive regulation of response to alcohol(GO:1901421)
0.1 0.5 GO:0014012 peripheral nervous system axon regeneration(GO:0014012)
0.1 0.3 GO:0044313 protein K6-linked deubiquitination(GO:0044313)
0.1 0.4 GO:1902303 negative regulation of potassium ion export(GO:1902303)
0.1 0.9 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)
0.1 0.3 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.1 2.7 GO:1905145 acetylcholine receptor signaling pathway(GO:0095500) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
0.1 0.4 GO:0035469 determination of pancreatic left/right asymmetry(GO:0035469)
0.1 0.3 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.1 0.3 GO:0034959 substance P catabolic process(GO:0010814) calcitonin catabolic process(GO:0010816) endothelin maturation(GO:0034959)
0.1 0.3 GO:0090126 protein complex assembly involved in synapse maturation(GO:0090126)
0.1 0.2 GO:0002343 peripheral B cell selection(GO:0002343) B cell affinity maturation(GO:0002344)
0.1 0.3 GO:1902938 regulation of intracellular calcium activated chloride channel activity(GO:1902938)
0.1 0.2 GO:0006667 sphinganine metabolic process(GO:0006667)
0.1 0.2 GO:0035622 intrahepatic bile duct development(GO:0035622)
0.1 0.2 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.1 0.2 GO:0035441 cell migration involved in vasculogenesis(GO:0035441)
0.1 0.4 GO:0007386 compartment pattern specification(GO:0007386)
0.1 0.3 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.1 0.8 GO:0021891 olfactory bulb interneuron development(GO:0021891)
0.1 0.7 GO:0006013 mannose metabolic process(GO:0006013)
0.1 0.3 GO:1903575 cornified envelope assembly(GO:1903575)
0.1 0.5 GO:2001015 negative regulation of skeletal muscle cell differentiation(GO:2001015)
0.1 0.4 GO:0032483 regulation of Rab protein signal transduction(GO:0032483)
0.1 0.2 GO:1900104 hyaluranon cable assembly(GO:0036118) regulation of hyaluranon cable assembly(GO:1900104) positive regulation of hyaluranon cable assembly(GO:1900106)
0.1 0.1 GO:0034165 positive regulation of toll-like receptor 9 signaling pathway(GO:0034165)
0.1 0.2 GO:0003032 detection of oxygen(GO:0003032) cardiac jelly development(GO:1905072)
0.1 0.5 GO:0015722 canalicular bile acid transport(GO:0015722)
0.1 0.2 GO:0043181 vacuolar sequestering(GO:0043181)
0.1 0.7 GO:1900194 receptor guanylyl cyclase signaling pathway(GO:0007168) negative regulation of oocyte maturation(GO:1900194)
0.1 0.3 GO:0006987 activation of signaling protein activity involved in unfolded protein response(GO:0006987)
0.1 0.3 GO:1902093 inner cell mass cell fate commitment(GO:0001827) positive regulation of sperm motility(GO:1902093)
0.1 0.1 GO:0002905 mature B cell apoptotic process(GO:0002901) regulation of mature B cell apoptotic process(GO:0002905) negative regulation of mature B cell apoptotic process(GO:0002906)
0.1 0.1 GO:0080144 amino acid homeostasis(GO:0080144)
0.1 0.3 GO:2000255 negative regulation of male germ cell proliferation(GO:2000255)
0.1 0.4 GO:0018992 germ-line sex determination(GO:0018992)
0.1 0.3 GO:0048807 female genitalia morphogenesis(GO:0048807) urinary bladder development(GO:0060157)
0.1 0.1 GO:0072289 metanephric nephron tubule formation(GO:0072289)
0.1 0.4 GO:0099550 trans-synaptic signalling, modulating synaptic transmission(GO:0099550)
0.1 0.4 GO:0051775 response to redox state(GO:0051775)
0.1 0.1 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.1 0.4 GO:2000344 positive regulation of acrosome reaction(GO:2000344)
0.1 0.3 GO:0006083 acetate metabolic process(GO:0006083)
0.1 0.2 GO:0000160 phosphorelay signal transduction system(GO:0000160)
0.1 0.2 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.1 0.2 GO:1900108 negative regulation of nodal signaling pathway(GO:1900108)
0.1 0.2 GO:0002415 immunoglobulin transcytosis in epithelial cells mediated by polymeric immunoglobulin receptor(GO:0002415)
0.1 0.3 GO:0060024 rhythmic synaptic transmission(GO:0060024)
0.1 0.4 GO:0030382 sperm mitochondrion organization(GO:0030382)
0.1 0.5 GO:0010793 regulation of mRNA export from nucleus(GO:0010793)
0.1 0.6 GO:1902474 positive regulation of protein localization to synapse(GO:1902474)
0.1 0.4 GO:0042590 antigen processing and presentation of exogenous peptide antigen via MHC class I(GO:0042590)
0.1 0.3 GO:2000987 positive regulation of fear response(GO:1903367) positive regulation of behavioral fear response(GO:2000987)
0.0 0.4 GO:0061713 neural crest cell migration involved in heart formation(GO:0003147) anterior neural tube closure(GO:0061713) cellular response to folic acid(GO:0071231)
0.0 0.6 GO:0052696 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.0 0.5 GO:0046598 positive regulation of viral entry into host cell(GO:0046598)
0.0 0.8 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.0 0.4 GO:0005513 detection of calcium ion(GO:0005513)
0.0 0.2 GO:0045590 negative regulation of regulatory T cell differentiation(GO:0045590)
0.0 0.3 GO:0015871 choline transport(GO:0015871) negative regulation of RIG-I signaling pathway(GO:0039536)
0.0 0.2 GO:0051012 microtubule sliding(GO:0051012)
0.0 0.8 GO:0005980 glycogen catabolic process(GO:0005980) glucan catabolic process(GO:0009251) cellular polysaccharide catabolic process(GO:0044247)
0.0 0.4 GO:1902166 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902166)
0.0 0.3 GO:0030242 pexophagy(GO:0030242)
0.0 0.2 GO:0002606 positive regulation of dendritic cell antigen processing and presentation(GO:0002606)
0.0 0.2 GO:0072602 interleukin-4 secretion(GO:0072602)
0.0 0.4 GO:0003062 regulation of heart rate by chemical signal(GO:0003062)
0.0 0.8 GO:0032060 bleb assembly(GO:0032060)
0.0 0.3 GO:0070317 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388) negative regulation of G0 to G1 transition(GO:0070317)
0.0 0.5 GO:0035845 photoreceptor cell outer segment organization(GO:0035845)
0.0 0.3 GO:0008228 opsonization(GO:0008228)
0.0 0.2 GO:0032430 positive regulation of phospholipase A2 activity(GO:0032430)
0.0 1.7 GO:0009409 response to cold(GO:0009409)
0.0 0.4 GO:0060136 embryonic process involved in female pregnancy(GO:0060136)
0.0 0.1 GO:0097026 dendritic cell dendrite assembly(GO:0097026)
0.0 0.7 GO:0060539 diaphragm development(GO:0060539)
0.0 0.3 GO:0051152 positive regulation of smooth muscle cell differentiation(GO:0051152)
0.0 0.2 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.0 0.3 GO:0061113 pancreas morphogenesis(GO:0061113)
0.0 0.4 GO:0070874 negative regulation of glycogen biosynthetic process(GO:0045719) negative regulation of glycogen metabolic process(GO:0070874)
0.0 0.4 GO:1904659 glucose transmembrane transport(GO:1904659)
0.0 0.2 GO:1903847 regulation of aorta morphogenesis(GO:1903847) positive regulation of aorta morphogenesis(GO:1903849)
0.0 0.1 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.0 0.2 GO:0006777 Mo-molybdopterin cofactor biosynthetic process(GO:0006777) Mo-molybdopterin cofactor metabolic process(GO:0019720)
0.0 0.5 GO:0035814 negative regulation of renal sodium excretion(GO:0035814)
0.0 0.4 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.4 GO:0070842 aggresome assembly(GO:0070842)
0.0 0.2 GO:0019695 choline metabolic process(GO:0019695)
0.0 0.1 GO:0002014 vasoconstriction of artery involved in ischemic response to lowering of systemic arterial blood pressure(GO:0002014)
0.0 0.1 GO:0090204 protein localization to nuclear pore(GO:0090204)
0.0 0.3 GO:0051386 regulation of neurotrophin TRK receptor signaling pathway(GO:0051386)
0.0 0.2 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)
0.0 0.7 GO:0046688 response to copper ion(GO:0046688)
0.0 0.8 GO:0014059 dopamine secretion(GO:0014046) regulation of dopamine secretion(GO:0014059)
0.0 0.1 GO:0097029 mature conventional dendritic cell differentiation(GO:0097029)
0.0 0.2 GO:0070305 response to cGMP(GO:0070305) cellular response to cGMP(GO:0071321)
0.0 1.1 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.2 GO:1903003 positive regulation of protein deubiquitination(GO:1903003)
0.0 0.4 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.1 GO:1904694 negative regulation of vascular smooth muscle contraction(GO:1904694)
0.0 0.3 GO:0046473 phosphatidic acid metabolic process(GO:0046473)
0.0 0.1 GO:0003165 Purkinje myocyte development(GO:0003165)
0.0 0.2 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.0 0.3 GO:0071285 cellular response to lithium ion(GO:0071285)
0.0 0.1 GO:0035470 positive regulation of vascular wound healing(GO:0035470)
0.0 0.1 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.0 0.5 GO:0032933 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.0 0.0 GO:0071608 macrophage inflammatory protein-1 alpha production(GO:0071608)
0.0 0.2 GO:0043562 cellular response to nitrogen starvation(GO:0006995) cellular response to nitrogen levels(GO:0043562)
0.0 0.2 GO:0046959 habituation(GO:0046959)
0.0 0.2 GO:0071684 blastocyst hatching(GO:0001835) hatching(GO:0035188) organism emergence from protective structure(GO:0071684)
0.0 0.1 GO:0001661 conditioned taste aversion(GO:0001661)
0.0 0.1 GO:0046210 nitrate catabolic process(GO:0043602) nitric oxide catabolic process(GO:0046210) cellular organohalogen metabolic process(GO:0090345) cellular organofluorine metabolic process(GO:0090346)
0.0 0.1 GO:1901678 iron coordination entity transport(GO:1901678)
0.0 0.6 GO:0035313 wound healing, spreading of epidermal cells(GO:0035313)
0.0 0.1 GO:0070829 heterochromatin maintenance(GO:0070829)
0.0 0.3 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.0 0.1 GO:0044375 regulation of peroxisome size(GO:0044375)
0.0 0.3 GO:0071712 ER-associated misfolded protein catabolic process(GO:0071712)
0.0 0.5 GO:0048266 behavioral response to pain(GO:0048266)
0.0 0.3 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.1 GO:0045358 negative regulation of interferon-beta biosynthetic process(GO:0045358)
0.0 0.3 GO:0051895 negative regulation of focal adhesion assembly(GO:0051895)
0.0 0.4 GO:0050962 detection of light stimulus involved in visual perception(GO:0050908) detection of light stimulus involved in sensory perception(GO:0050962)
0.0 0.1 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.0 0.1 GO:0090315 negative regulation of protein targeting to membrane(GO:0090315)
0.0 0.3 GO:0048148 behavioral response to cocaine(GO:0048148)
0.0 0.1 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.0 0.1 GO:0090527 actin filament reorganization(GO:0090527)
0.0 0.0 GO:0061090 positive regulation of sequestering of zinc ion(GO:0061090)
0.0 0.1 GO:0060700 regulation of ribonuclease activity(GO:0060700)
0.0 0.2 GO:0033234 negative regulation of protein sumoylation(GO:0033234)
0.0 0.1 GO:0090385 phagosome-lysosome fusion(GO:0090385)
0.0 0.0 GO:0098968 neurotransmitter receptor transport postsynaptic membrane to endosome(GO:0098968)
0.0 0.4 GO:0006677 glycosylceramide metabolic process(GO:0006677)
0.0 0.2 GO:0044036 cell wall macromolecule catabolic process(GO:0016998) cell wall macromolecule metabolic process(GO:0044036) cell wall organization or biogenesis(GO:0071554)
0.0 0.1 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.0 0.1 GO:0010838 positive regulation of keratinocyte proliferation(GO:0010838)
0.0 0.0 GO:0032474 otolith morphogenesis(GO:0032474)
0.0 0.2 GO:1902187 negative regulation of viral release from host cell(GO:1902187)
0.0 0.1 GO:0090235 regulation of metaphase plate congression(GO:0090235) regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.0 0.0 GO:0030043 actin filament fragmentation(GO:0030043)
0.0 0.3 GO:0030220 platelet formation(GO:0030220)
0.0 0.0 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.0 0.1 GO:0006516 glycoprotein catabolic process(GO:0006516)
0.0 0.1 GO:0097491 trigeminal nerve morphogenesis(GO:0021636) trigeminal nerve structural organization(GO:0021637) trunk segmentation(GO:0035290) trunk neural crest cell migration(GO:0036484) ventral trunk neural crest cell migration(GO:0036486) sympathetic neuron projection extension(GO:0097490) sympathetic neuron projection guidance(GO:0097491) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
0.0 0.2 GO:0050907 detection of chemical stimulus involved in sensory perception(GO:0050907)
0.0 0.5 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 0.1 GO:0040031 snRNA modification(GO:0040031)
0.0 0.0 GO:0002874 regulation of chronic inflammatory response to antigenic stimulus(GO:0002874)
0.0 0.1 GO:0006116 NADH oxidation(GO:0006116)
0.0 0.1 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.0 0.1 GO:0032346 positive regulation of aldosterone metabolic process(GO:0032346) positive regulation of aldosterone biosynthetic process(GO:0032349) leading edge cell differentiation(GO:0035026)
0.0 0.2 GO:0007141 male meiosis I(GO:0007141)
0.0 0.1 GO:0031937 positive regulation of chromatin silencing(GO:0031937)
0.0 0.2 GO:0048681 negative regulation of axon regeneration(GO:0048681)
0.0 0.1 GO:0044829 positive regulation by host of viral genome replication(GO:0044829)
0.0 0.2 GO:2000353 positive regulation of endothelial cell apoptotic process(GO:2000353)
0.0 0.1 GO:0030259 lipid glycosylation(GO:0030259)
0.0 0.0 GO:0097527 necroptotic signaling pathway(GO:0097527) positive regulation of CD8-positive, alpha-beta T cell extravasation(GO:2000451)
0.0 0.1 GO:0002322 B cell proliferation involved in immune response(GO:0002322) positive regulation of lipopolysaccharide-mediated signaling pathway(GO:0031666)
0.0 0.1 GO:0000712 resolution of meiotic recombination intermediates(GO:0000712)
0.0 0.0 GO:0021759 globus pallidus development(GO:0021759)
0.0 0.0 GO:0086053 AV node cell to bundle of His cell communication by electrical coupling(GO:0086053)
0.0 0.1 GO:0035509 negative regulation of myosin-light-chain-phosphatase activity(GO:0035509)
0.0 0.0 GO:1901950 dense core granule localization(GO:0032253) cellular response to isoquinoline alkaloid(GO:0071317) dense core granule transport(GO:1901950) regulation of dense core granule transport(GO:1904809) positive regulation of dense core granule transport(GO:1904811)
0.0 0.4 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.1 GO:0002328 pro-B cell differentiation(GO:0002328)
0.0 0.1 GO:0035855 megakaryocyte development(GO:0035855)
0.0 0.1 GO:0098909 regulation of cardiac muscle cell action potential involved in regulation of contraction(GO:0098909)
0.0 0.5 GO:0007520 myoblast fusion(GO:0007520)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.6 GO:0034365 discoidal high-density lipoprotein particle(GO:0034365)
0.2 0.9 GO:1902937 inward rectifier potassium channel complex(GO:1902937)
0.2 0.6 GO:0097233 lamellar body membrane(GO:0097232) alveolar lamellar body membrane(GO:0097233)
0.2 0.7 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.2 0.5 GO:0046691 intracellular canaliculus(GO:0046691)
0.1 0.5 GO:1902636 kinociliary basal body(GO:1902636)
0.1 1.3 GO:0031983 vesicle lumen(GO:0031983)
0.1 0.4 GO:0097543 ciliary inversin compartment(GO:0097543)
0.1 1.4 GO:0043083 synaptic cleft(GO:0043083)
0.1 1.0 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.1 0.3 GO:0036488 CHOP-C/EBP complex(GO:0036488)
0.1 0.3 GO:0032280 symmetric synapse(GO:0032280)
0.1 0.3 GO:0032127 dense core granule membrane(GO:0032127)
0.1 0.2 GO:0032311 angiogenin-PRI complex(GO:0032311)
0.1 0.3 GO:1990604 IRE1-TRAF2-ASK1 complex(GO:1990604)
0.1 0.2 GO:0071953 elastic fiber(GO:0071953)
0.1 1.0 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.1 0.3 GO:1990769 proximal neuron projection(GO:1990769)
0.1 0.2 GO:0098855 HCN channel complex(GO:0098855)
0.0 0.7 GO:0017119 Golgi transport complex(GO:0017119)
0.0 1.1 GO:0034706 sodium channel complex(GO:0034706)
0.0 0.4 GO:0042825 TAP complex(GO:0042825)
0.0 0.3 GO:0019815 B cell receptor complex(GO:0019815)
0.0 0.7 GO:0031528 microvillus membrane(GO:0031528)
0.0 0.8 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)
0.0 1.2 GO:0016460 myosin II complex(GO:0016460)
0.0 0.3 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.1 GO:0031021 interphase microtubule organizing center(GO:0031021)
0.0 0.2 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.0 0.1 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.0 0.1 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.3 GO:0033093 Weibel-Palade body(GO:0033093)
0.0 0.2 GO:0097443 sorting endosome(GO:0097443)
0.0 0.1 GO:0005958 DNA-dependent protein kinase-DNA ligase 4 complex(GO:0005958) DNA ligase IV complex(GO:0032807) ERCC4-ERCC1 complex(GO:0070522)
0.0 0.2 GO:0097227 sperm annulus(GO:0097227)
0.0 0.1 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.0 0.1 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.0 0.3 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 1.0 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.6 GO:0005732 small nucleolar ribonucleoprotein complex(GO:0005732)
0.0 0.1 GO:0001652 granular component(GO:0001652)
0.0 0.4 GO:0031362 anchored component of external side of plasma membrane(GO:0031362)
0.0 0.5 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.1 GO:0070022 transforming growth factor beta receptor homodimeric complex(GO:0070022)
0.0 0.2 GO:0044754 autolysosome(GO:0044754)
0.0 0.2 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.1 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.0 0.2 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0 0.1 GO:0031084 BLOC-2 complex(GO:0031084)
0.0 0.6 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.3 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 2.2 GO:0031225 anchored component of membrane(GO:0031225)
0.0 1.4 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 0.7 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.1 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.0 1.5 GO:0005901 caveola(GO:0005901)
0.0 0.1 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.0 GO:0044194 cytolytic granule(GO:0044194)
0.0 0.4 GO:0030665 clathrin-coated vesicle membrane(GO:0030665)
0.0 0.6 GO:0031901 early endosome membrane(GO:0031901)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0046911 metal chelating activity(GO:0046911)
0.3 2.3 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.3 1.1 GO:0004104 cholinesterase activity(GO:0004104)
0.2 0.6 GO:0035575 histone demethylase activity (H4-K20 specific)(GO:0035575)
0.2 0.5 GO:0070546 L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.2 0.7 GO:0004566 beta-glucuronidase activity(GO:0004566)
0.2 0.5 GO:0004771 sterol esterase activity(GO:0004771)
0.2 0.6 GO:0008184 glycogen phosphorylase activity(GO:0008184)
0.1 0.7 GO:0016941 natriuretic peptide receptor activity(GO:0016941)
0.1 0.4 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.1 0.4 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.1 0.6 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.1 1.5 GO:0015250 water channel activity(GO:0015250)
0.1 0.5 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.1 0.3 GO:0019807 aspartoacylase activity(GO:0019807)
0.1 0.7 GO:0000155 phosphorelay sensor kinase activity(GO:0000155)
0.1 0.4 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.1 0.3 GO:0017082 mineralocorticoid receptor activity(GO:0017082)
0.1 0.3 GO:0008107 galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127)
0.1 0.5 GO:0002046 opsin binding(GO:0002046)
0.1 0.4 GO:2001070 starch binding(GO:2001070)
0.1 0.3 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.1 0.2 GO:0036132 13-prostaglandin reductase activity(GO:0036132) 15-oxoprostaglandin 13-oxidase activity(GO:0047522)
0.1 0.2 GO:0033265 choline binding(GO:0033265)
0.1 0.7 GO:0005007 fibroblast growth factor-activated receptor activity(GO:0005007)
0.1 0.7 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.1 0.4 GO:0032810 sterol response element binding(GO:0032810)
0.1 0.7 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.1 0.2 GO:0038100 nodal binding(GO:0038100)
0.1 0.8 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.1 0.3 GO:1904288 BAT3 complex binding(GO:1904288)
0.1 0.4 GO:0071723 lipopeptide binding(GO:0071723)
0.1 0.5 GO:0050786 RAGE receptor binding(GO:0050786)
0.1 0.4 GO:0005030 neurotrophin receptor activity(GO:0005030)
0.1 0.2 GO:0004619 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.1 0.2 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.1 0.2 GO:0042284 sphingolipid delta-4 desaturase activity(GO:0042284)
0.1 0.2 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.1 0.6 GO:0015280 ligand-gated sodium channel activity(GO:0015280)
0.1 0.3 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427)
0.1 0.2 GO:0050501 hyaluronan synthase activity(GO:0050501)
0.1 0.2 GO:0004574 oligo-1,6-glucosidase activity(GO:0004574)
0.1 0.4 GO:0046978 TAP1 binding(GO:0046978) TAP2 binding(GO:0046979)
0.1 0.8 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.4 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 0.2 GO:0070051 fibrinogen binding(GO:0070051)
0.0 1.3 GO:0047617 acyl-CoA hydrolase activity(GO:0047617)
0.0 0.2 GO:0034584 piRNA binding(GO:0034584)
0.0 0.4 GO:0005412 glucose:sodium symporter activity(GO:0005412)
0.0 0.3 GO:0004957 prostaglandin E receptor activity(GO:0004957)
0.0 0.4 GO:0051870 methotrexate binding(GO:0051870)
0.0 2.4 GO:0005158 insulin receptor binding(GO:0005158)
0.0 0.2 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.0 0.1 GO:0001729 ceramide kinase activity(GO:0001729)
0.0 0.3 GO:0001515 opioid peptide activity(GO:0001515)
0.0 0.2 GO:0005534 galactose binding(GO:0005534)
0.0 0.7 GO:0016208 AMP binding(GO:0016208)
0.0 0.4 GO:0004185 serine-type carboxypeptidase activity(GO:0004185)
0.0 0.1 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.0 0.5 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 0.4 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.0 0.1 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.0 0.1 GO:1903135 cupric ion binding(GO:1903135)
0.0 0.7 GO:0070006 metalloaminopeptidase activity(GO:0070006)
0.0 0.2 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.0 0.1 GO:0070905 serine binding(GO:0070905)
0.0 0.5 GO:0030159 receptor signaling complex scaffold activity(GO:0030159)
0.0 0.4 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.0 0.2 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.0 0.1 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.0 0.1 GO:0008410 CoA-transferase activity(GO:0008410)
0.0 0.2 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 0.3 GO:0097109 neuroligin family protein binding(GO:0097109)
0.0 0.2 GO:0019763 immunoglobulin receptor activity(GO:0019763)
0.0 0.2 GO:0017077 oxidative phosphorylation uncoupler activity(GO:0017077)
0.0 0.5 GO:0017166 vinculin binding(GO:0017166)
0.0 0.2 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.0 GO:0046848 hydroxyapatite binding(GO:0046848)
0.0 0.5 GO:0005248 voltage-gated sodium channel activity(GO:0005248)
0.0 0.1 GO:1990599 3' overhang single-stranded DNA endodeoxyribonuclease activity(GO:1990599)
0.0 0.1 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.0 0.4 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.3 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 0.1 GO:0047726 nitric oxide dioxygenase activity(GO:0008941) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor(GO:0016708) iron-cytochrome-c reductase activity(GO:0047726)
0.0 0.1 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.0 0.1 GO:0070915 lysophosphatidic acid binding(GO:0035727) lysophosphatidic acid receptor activity(GO:0070915)
0.0 0.3 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.0 0.1 GO:0005095 GTPase inhibitor activity(GO:0005095)
0.0 0.3 GO:0008242 omega peptidase activity(GO:0008242)
0.0 0.1 GO:0015923 mannosidase activity(GO:0015923)
0.0 0.1 GO:0004090 carbonyl reductase (NADPH) activity(GO:0004090)
0.0 0.2 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.0 0.4 GO:0015269 calcium-activated potassium channel activity(GO:0015269)
0.0 0.5 GO:0031489 myosin V binding(GO:0031489)
0.0 0.6 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.1 GO:0030977 taurine binding(GO:0030977)
0.0 0.4 GO:0050431 transforming growth factor beta binding(GO:0050431)
0.0 0.3 GO:0019841 retinal binding(GO:0016918) retinol binding(GO:0019841)
0.0 0.1 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.7 GO:0043014 alpha-tubulin binding(GO:0043014)
0.0 0.1 GO:0005093 Rab GDP-dissociation inhibitor activity(GO:0005093)
0.0 0.1 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.0 0.1 GO:0047045 testosterone 17-beta-dehydrogenase (NADP+) activity(GO:0047045)
0.0 0.1 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.0 0.1 GO:0032139 dinucleotide insertion or deletion binding(GO:0032139) single guanine insertion binding(GO:0032142)
0.0 0.3 GO:0001013 RNA polymerase I regulatory region DNA binding(GO:0001013)
0.0 0.3 GO:0015299 solute:proton antiporter activity(GO:0015299)
0.0 0.2 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.5 GO:0001968 fibronectin binding(GO:0001968)
0.0 0.7 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.1 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.2 GO:0003796 lysozyme activity(GO:0003796)
0.0 0.2 GO:0034987 immunoglobulin receptor binding(GO:0034987)
0.0 0.5 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.0 0.4 GO:0050998 nitric-oxide synthase binding(GO:0050998)
0.0 0.1 GO:0015189 L-lysine transmembrane transporter activity(GO:0015189)
0.0 0.2 GO:0003988 acetyl-CoA C-acyltransferase activity(GO:0003988)
0.0 0.2 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.1 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.0 0.0 GO:0016361 activin receptor activity, type I(GO:0016361)
0.0 0.2 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.0 GO:0016933 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 0.1 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 1.2 GO:0019905 syntaxin binding(GO:0019905)
0.0 0.4 GO:0050699 WW domain binding(GO:0050699)
0.0 0.0 GO:0086077 gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling(GO:0086077)
0.0 0.1 GO:0008656 cysteine-type endopeptidase activator activity involved in apoptotic process(GO:0008656)
0.0 0.1 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.2 GO:0005229 intracellular calcium activated chloride channel activity(GO:0005229)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 PID A6B1 A6B4 INTEGRIN PATHWAY a6b1 and a6b4 Integrin signaling
0.0 0.7 PID WNT SIGNALING PATHWAY Wnt signaling network
0.0 0.7 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.7 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 1.4 PID HNF3B PATHWAY FOXA2 and FOXA3 transcription factor networks
0.0 0.2 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 1.7 PID ERA GENOMIC PATHWAY Validated nuclear estrogen receptor alpha network
0.0 0.6 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.5 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.0 0.7 PID RET PATHWAY Signaling events regulated by Ret tyrosine kinase
0.0 0.3 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.1 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.6 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.4 PID LIS1 PATHWAY Lissencephaly gene (LIS1) in neuronal migration and development
0.0 0.1 PID GLYPICAN 1PATHWAY Glypican 1 network
0.0 0.5 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 0.3 PID SYNDECAN 4 PATHWAY Syndecan-4-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.6 REACTOME HDL MEDIATED LIPID TRANSPORT Genes involved in HDL-mediated lipid transport
0.1 1.4 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 0.8 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.1 0.4 REACTOME BETA DEFENSINS Genes involved in Beta defensins
0.1 1.0 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.5 REACTOME PASSIVE TRANSPORT BY AQUAPORINS Genes involved in Passive Transport by Aquaporins
0.0 1.4 REACTOME SYNTHESIS OF PC Genes involved in Synthesis of PC
0.0 0.2 REACTOME SIGNALING BY FGFR Genes involved in Signaling by FGFR
0.0 1.3 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.0 0.5 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.0 0.5 REACTOME ADVANCED GLYCOSYLATION ENDPRODUCT RECEPTOR SIGNALING Genes involved in Advanced glycosylation endproduct receptor signaling
0.0 0.6 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.7 REACTOME FGFR LIGAND BINDING AND ACTIVATION Genes involved in FGFR ligand binding and activation
0.0 0.3 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 0.3 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.5 REACTOME CYTOCHROME P450 ARRANGED BY SUBSTRATE TYPE Genes involved in Cytochrome P450 - arranged by substrate type
0.0 1.0 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.4 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.2 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.2 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.7 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.2 REACTOME TRAFFICKING AND PROCESSING OF ENDOSOMAL TLR Genes involved in Trafficking and processing of endosomal TLR
0.0 0.3 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.3 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 0.4 REACTOME CGMP EFFECTS Genes involved in cGMP effects
0.0 0.2 REACTOME INTEGRIN CELL SURFACE INTERACTIONS Genes involved in Integrin cell surface interactions
0.0 0.3 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.4 REACTOME RORA ACTIVATES CIRCADIAN EXPRESSION Genes involved in RORA Activates Circadian Expression
0.0 0.3 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.5 REACTOME VOLTAGE GATED POTASSIUM CHANNELS Genes involved in Voltage gated Potassium channels
0.0 0.1 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 0.2 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL