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2D miR_HR1_12

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Results for Prrx1_Isx_Prrxl1

Z-value: 0.70

Motif logo

Transcription factors associated with Prrx1_Isx_Prrxl1

Gene Symbol Gene ID Gene Info
ENSMUSG00000026586.10 paired related homeobox 1
ENSMUSG00000031621.3 intestine specific homeobox
ENSMUSG00000041730.7 paired related homeobox protein-like 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Prrx1mm10_v2_chr1_-_163289214_1632892350.421.7e-01Click!
Isxmm10_v2_chr8_+_74873540_748736150.225.0e-01Click!

Activity profile of Prrx1_Isx_Prrxl1 motif

Sorted Z-values of Prrx1_Isx_Prrxl1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr12_+_79297345 1.33 ENSMUST00000079533.5
ENSMUST00000171210.1
RAD51 homolog B
chr17_+_27556641 1.27 ENSMUST00000119486.1
ENSMUST00000118599.1
high mobility group AT-hook 1
chr17_+_27556668 1.19 ENSMUST00000117254.1
ENSMUST00000118570.1
high mobility group AT-hook 1
chr17_+_27556613 1.13 ENSMUST00000117600.1
ENSMUST00000114888.3
high mobility group AT-hook 1
chr9_-_48911067 1.07 ENSMUST00000003826.7
5-hydroxytryptamine (serotonin) receptor 3A
chr16_-_17144415 0.80 ENSMUST00000115709.1
coiled-coil domain containing 116
chr13_+_104229366 0.77 ENSMUST00000022227.6
centromere protein K
chr8_-_105568298 0.75 ENSMUST00000005849.5
agouti related protein
chr1_-_158356258 0.67 ENSMUST00000004133.8
bone morphogenic protein/retinoic acid inducible neural-specific 2
chr14_+_4023941 0.65 ENSMUST00000096184.4
predicted gene 5796
chr7_+_45621805 0.64 ENSMUST00000033100.4
izumo sperm-egg fusion 1
chr9_-_71896047 0.64 ENSMUST00000184448.1
transcription factor 12
chr7_+_102441685 0.62 ENSMUST00000033283.9
ribonucleotide reductase M1
chr7_+_126862431 0.60 ENSMUST00000132808.1
HIRA interacting protein 3
chr2_+_119047116 0.59 ENSMUST00000152380.1
ENSMUST00000099542.2
cancer susceptibility candidate 5
chr15_-_9140374 0.56 ENSMUST00000096482.3
ENSMUST00000110585.2
S-phase kinase-associated protein 2 (p45)
chr1_-_130661613 0.55 ENSMUST00000027657.7
complement component 4 binding protein
chr7_+_126695355 0.51 ENSMUST00000130498.1
bolA-like 2 (E. coli)
chr7_+_100159241 0.51 ENSMUST00000032967.3
lipoyl(octanoyl) transferase 2 (putative)
chrM_+_11734 0.51 ENSMUST00000082418.1
mitochondrially encoded NADH dehydrogenase 5
chr6_-_34317442 0.50 ENSMUST00000154655.1
ENSMUST00000102980.4
aldo-keto reductase family 1, member B3 (aldose reductase)
chr17_-_48432723 0.49 ENSMUST00000046549.3
apolipoprotein B mRNA editing enzyme, catalytic polypeptide 2
chr3_+_86070915 0.48 ENSMUST00000182666.1
SH3 domain protein D19
chr11_-_59163281 0.47 ENSMUST00000069631.2
IBA57, iron-sulfur cluster assembly homolog (S. cerevisiae)
chr10_+_23851454 0.47 ENSMUST00000020190.7
vanin 3
chr2_-_113848655 0.46 ENSMUST00000102545.1
ENSMUST00000110948.1
Rho GTPase activating protein 11A
chr4_+_95557494 0.46 ENSMUST00000079223.4
ENSMUST00000177394.1
FGGY carbohydrate kinase domain containing
chr4_-_87806296 0.45 ENSMUST00000126353.1
ENSMUST00000149357.1
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr11_-_12412136 0.45 ENSMUST00000174874.1
cordon-bleu WH2 repeat
chr2_-_164638789 0.44 ENSMUST00000109336.1
WAP four-disulfide core domain 16
chr12_+_117843489 0.44 ENSMUST00000021592.9
cell division cycle associated 7 like
chrX_-_94212638 0.43 ENSMUST00000113922.1
eukaryotic translation initiation factor 2, subunit 3, structural gene X-linked
chr17_+_56613392 0.42 ENSMUST00000080492.5
ribosomal protein L36
chr14_-_54517353 0.42 ENSMUST00000023873.5
protein arginine N-methyltransferase 5
chr14_-_101609033 0.41 ENSMUST00000161991.1
ENSMUST00000100340.3
TBC1 domain family, member 4
chr12_-_79190955 0.40 ENSMUST00000085254.6
retinol dehydrogenase 11
chr3_-_32985076 0.40 ENSMUST00000108221.1
peroxisomal biogenesis factor 5-like
chr14_-_104522615 0.40 ENSMUST00000022716.2
ring finger protein 219
chr1_-_130661584 0.40 ENSMUST00000137276.2
complement component 4 binding protein
chr4_-_87806276 0.39 ENSMUST00000148059.1
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3
chr18_+_4375583 0.39 ENSMUST00000025077.6
mitochondrial poly(A) polymerase
chr14_-_118923070 0.38 ENSMUST00000047208.5
DAZ interacting protein 1
chr2_-_73452666 0.36 ENSMUST00000151939.1
WAS/WASL interacting protein family, member 1
chr13_+_96388294 0.36 ENSMUST00000099295.4
POC5 centriolar protein homolog (Chlamydomonas)
chr6_+_17749170 0.35 ENSMUST00000053148.7
ENSMUST00000115417.3
suppression of tumorigenicity 7
chr14_-_67072465 0.34 ENSMUST00000089230.5
protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 52), alpha isoform
chr6_+_122513583 0.34 ENSMUST00000032210.7
ENSMUST00000148517.1
microfibrillar associated protein 5
chr1_-_133610253 0.34 ENSMUST00000166915.1
small nuclear ribonucleoprotein E
chr12_+_65225513 0.33 ENSMUST00000046331.4
WD repeat domain 20b
chr7_+_132610620 0.32 ENSMUST00000033241.5
phospholysine phosphohistidine inorganic pyrophosphate phosphatase
chrX_-_134541847 0.32 ENSMUST00000054213.4
translocase of inner mitochondrial membrane 8A1
chrM_+_7759 0.31 ENSMUST00000082407.1
ENSMUST00000082408.1
mitochondrially encoded ATP synthase 8
mitochondrially encoded ATP synthase 6
chr18_+_60774675 0.31 ENSMUST00000118551.1
ribosomal protein S14
chr15_+_76343504 0.31 ENSMUST00000023210.6
cytochrome c-1
chr1_-_4785671 0.31 ENSMUST00000130201.1
ENSMUST00000156816.1
mitochondrial ribosomal protein L15
chrX_+_106015699 0.30 ENSMUST00000033582.4
cytochrome c oxidase subunit VIIb
chr4_+_126556935 0.30 ENSMUST00000048391.8
claspin
chr2_-_17460610 0.30 ENSMUST00000145492.1
nebulette
chr18_+_60774510 0.30 ENSMUST00000025511.3
ribosomal protein S14
chr11_+_58171648 0.30 ENSMUST00000020820.1
mitochondrial ribosomal protein L22
chr3_-_88410295 0.29 ENSMUST00000056370.7
polyamine-modulated factor 1
chr11_-_54249640 0.29 ENSMUST00000019060.5
colony stimulating factor 2 (granulocyte-macrophage)
chr17_-_37483543 0.28 ENSMUST00000016427.4
ENSMUST00000171139.2
histocompatibility 2, M region locus 2
chr5_-_62766153 0.28 ENSMUST00000076623.4
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chrX_-_134111852 0.28 ENSMUST00000033610.6
NADPH oxidase 1
chr2_+_112492926 0.28 ENSMUST00000003705.5
apoptosis, caspase activation inhibitor
chr4_-_32923455 0.27 ENSMUST00000035719.4
ENSMUST00000084749.1
ankyrin repeat domain 6
chr2_-_119662756 0.27 ENSMUST00000028768.1
ENSMUST00000110801.1
ENSMUST00000110802.1
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 1
chr17_+_46496753 0.27 ENSMUST00000046497.6
2'-deoxynucleoside 5'-phosphate N-hydrolase 1
chr18_+_37411674 0.27 ENSMUST00000051126.2
protocadherin beta 10
chr10_-_128626464 0.27 ENSMUST00000026420.5
ribosomal protein S26
chr14_-_40893222 0.26 ENSMUST00000096000.3
SH2 domain containing 4B
chr19_+_38395980 0.26 ENSMUST00000054098.2
solute carrier family 35, member G1
chr16_+_45224315 0.26 ENSMUST00000102802.3
ENSMUST00000063654.4
B and T lymphocyte associated
chr16_+_56204313 0.25 ENSMUST00000160116.1
ENSMUST00000069936.7
interphotoreceptor matrix proteoglycan 2
chrY_+_90785442 0.25 ENSMUST00000177591.1
ENSMUST00000177671.1
ENSMUST00000179077.1
erythroid differentiation regulator 1
chr13_-_4609122 0.25 ENSMUST00000110691.3
ENSMUST00000091848.5
aldo-keto reductase family 1, member E1
chr18_-_47333311 0.25 ENSMUST00000126684.1
ENSMUST00000156422.1
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A
chr9_+_64281575 0.25 ENSMUST00000034964.6
timeless interacting protein
chrM_+_9870 0.24 ENSMUST00000084013.1
mitochondrially encoded NADH dehydrogenase 4L
chr18_+_69593361 0.24 ENSMUST00000114978.2
ENSMUST00000114977.1
transcription factor 4
chr10_-_41303171 0.23 ENSMUST00000043814.3
FIG4 homolog (S. cerevisiae)
chr14_-_5455467 0.23 ENSMUST00000180867.1
predicted gene 3194
chr8_-_70527945 0.22 ENSMUST00000138260.1
ENSMUST00000117580.1
KxDL motif containing 1
chr15_+_92344359 0.22 ENSMUST00000181901.1
predicted gene, 26760
chr16_+_16870829 0.22 ENSMUST00000131063.1
topoisomerase (DNA) III beta
chr4_+_126556994 0.22 ENSMUST00000147675.1
claspin
chr3_-_86142684 0.22 ENSMUST00000029722.6
ribosomal protein S3A1
chr3_+_94377432 0.22 ENSMUST00000107292.1
RAR-related orphan receptor gamma
chr13_-_58354862 0.22 ENSMUST00000043605.5
kinesin family member 27
chr10_+_128232065 0.22 ENSMUST00000055539.4
ENSMUST00000105244.1
ENSMUST00000105243.2
ENSMUST00000125289.1
ENSMUST00000105242.1
timeless circadian clock 1
chr16_-_55283237 0.22 ENSMUST00000036412.3
zona pellucida like domain containing 1
chr18_+_4994600 0.21 ENSMUST00000140448.1
supervillin
chr3_-_33082004 0.21 ENSMUST00000108225.3
peroxisomal biogenesis factor 5-like
chrX_+_107089234 0.20 ENSMUST00000118666.1
ENSMUST00000053375.3
purinergic receptor P2Y, G-protein coupled 10
chr3_-_98339921 0.20 ENSMUST00000065793.5
3-phosphoglycerate dehydrogenase
chr3_+_133338936 0.20 ENSMUST00000150386.1
ENSMUST00000125858.1
pyrophosphatase (inorganic) 2
chr4_+_126046903 0.20 ENSMUST00000030675.7
mitochondrial ribosomal protein S15
chr3_+_87906842 0.20 ENSMUST00000159492.1
hepatoma-derived growth factor
chr1_-_176807124 0.20 ENSMUST00000057037.7
centrosomal protein 170
chr1_-_24612700 0.20 ENSMUST00000088336.1
predicted gene 10222
chr1_+_85575676 0.20 ENSMUST00000178024.1
RIKEN cDNA G530012D1 gene
chr2_+_65620829 0.19 ENSMUST00000028377.7
sodium channel, voltage-gated, type II, alpha 1
chr14_-_18893376 0.19 ENSMUST00000151926.1
ubiquitin-conjugating enzyme E2E 2
chr3_+_32515295 0.19 ENSMUST00000029203.7
zinc finger protein 639
chr13_+_92425896 0.19 ENSMUST00000061594.6
ankyrin repeat domain 34B
chr5_+_109940426 0.19 ENSMUST00000170826.1
predicted gene 15446
chr10_+_127421208 0.18 ENSMUST00000168780.1
R3H domain containing 2
chr5_+_8798139 0.18 ENSMUST00000009058.5
ATP-binding cassette, sub-family B (MDR/TAP), member 1B
chrX_+_7580483 0.18 ENSMUST00000115738.1
forkhead box P3
chr18_+_75000469 0.18 ENSMUST00000079716.5
ribosomal protein L17
chr8_-_122915987 0.18 ENSMUST00000098333.4
ankyrin repeat domain 11
chr6_+_34745952 0.18 ENSMUST00000123823.1
ENSMUST00000136907.1
ENSMUST00000126181.1
caldesmon 1
chr19_+_11404735 0.18 ENSMUST00000153546.1
membrane-spanning 4-domains, subfamily A, member 4C
chr18_+_35553401 0.18 ENSMUST00000181664.1
small nucleolar RNA host gene 4 (non-protein coding)
chr16_-_90810365 0.18 ENSMUST00000140920.1
URB1 ribosome biogenesis 1 homolog (S. cerevisiae)
chr2_+_158666690 0.18 ENSMUST00000103116.3
protein phosphatase 1, regulatory (inhibitor) subunit 16B
chr8_-_93131271 0.17 ENSMUST00000034189.8
carboxylesterase 1C
chr18_+_3382979 0.17 ENSMUST00000025073.5
cullin 2
chr10_+_128747850 0.17 ENSMUST00000163377.2
within bgcn homolog (Drosophila)
chr17_-_15498263 0.16 ENSMUST00000014913.9
proteasome (prosome, macropain) subunit, beta type 1
chrX_+_38600626 0.16 ENSMUST00000000365.2
malignant T cell amplified sequence 1
chr8_-_62123106 0.16 ENSMUST00000034052.6
ENSMUST00000034054.7
annexin A10
chr14_-_118052235 0.16 ENSMUST00000022725.2
dopachrome tautomerase
chr2_-_170194033 0.16 ENSMUST00000180625.1
predicted gene, 17619
chr17_+_94873986 0.16 ENSMUST00000108007.4
predicted gene, 20939
chr17_-_45686899 0.16 ENSMUST00000156254.1
transmembrane protein 63b
chr16_-_44332925 0.16 ENSMUST00000136381.1
SID1 transmembrane family, member 1
chr14_+_63992425 0.16 ENSMUST00000058229.4
retinitis pigmentosa 1 homolog (human)-like 1
chr6_+_34746368 0.16 ENSMUST00000142716.1
caldesmon 1
chr8_-_84969412 0.15 ENSMUST00000147812.1
ribonuclease H2, large subunit
chr1_-_171240055 0.15 ENSMUST00000131286.1
NADH dehydrogenase (ubiquinone) Fe-S protein 2
chr4_+_59035088 0.15 ENSMUST00000041160.6
guanine nucleotide binding protein (G protein), gamma 10
chr2_+_116067213 0.15 ENSMUST00000152412.1
RIKEN cDNA G630016G05 gene
chr13_-_81570640 0.15 ENSMUST00000109565.2
G protein-coupled receptor 98
chr6_+_115422040 0.15 ENSMUST00000000450.3
peroxisome proliferator activated receptor gamma
chr16_+_16870736 0.15 ENSMUST00000139740.1
ENSMUST00000119787.2
ENSMUST00000130650.1
ENSMUST00000156502.1
ENSMUST00000023465.7
ENSMUST00000124960.1
ENSMUST00000144513.1
topoisomerase (DNA) III beta
chr9_+_75051977 0.14 ENSMUST00000170310.1
ENSMUST00000166549.1
cAMP-regulated phosphoprotein 19
chr2_+_121956651 0.14 ENSMUST00000110574.1
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
chr10_-_127189981 0.14 ENSMUST00000019611.7
Rho guanine nucleotide exchange factor (GEF) 25
chr17_+_78508063 0.14 ENSMUST00000024880.9
vitrin
chr7_+_19508712 0.14 ENSMUST00000002112.8
ENSMUST00000108455.1
trafficking protein particle complex 6A
chr11_+_53433299 0.14 ENSMUST00000018382.6
growth differentiation factor 9
chr14_-_57571551 0.14 ENSMUST00000022518.5
N-6 adenine-specific DNA methyltransferase 2 (putative)
chr2_+_121506748 0.14 ENSMUST00000099473.3
ENSMUST00000110602.2
WD repeat domain 76
chr14_+_24490678 0.14 ENSMUST00000169826.1
ENSMUST00000112384.3
ribosomal protein S24
chr11_-_102185239 0.14 ENSMUST00000021297.5
LSM12 homolog (S. cerevisiae)
chr17_-_35027909 0.14 ENSMUST00000040151.2
suppressor APC domain containing 1
chr11_-_84129582 0.14 ENSMUST00000018795.6
transcriptional adaptor 2A
chr12_+_85110833 0.14 ENSMUST00000053811.8
dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)
chr4_-_147868631 0.13 ENSMUST00000030886.8
ENSMUST00000172710.1
migration and invasion inhibitory protein
chr9_+_35423582 0.13 ENSMUST00000154652.1
cell adhesion molecule-related/down-regulated by oncogenes
chr7_-_79386943 0.13 ENSMUST00000053718.8
ENSMUST00000179243.1
retinaldehyde binding protein 1
chr4_+_13751297 0.13 ENSMUST00000105566.2
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr1_-_186117251 0.13 ENSMUST00000045388.7
lysophospholipase-like 1
chr7_-_127895578 0.13 ENSMUST00000033074.6
vitamin K epoxide reductase complex, subunit 1
chr13_+_49504774 0.13 ENSMUST00000051504.7
extracellular matrix protein 2, female organ and adipocyte specific
chrX_-_162964557 0.13 ENSMUST00000038769.2
S100 calcium binding protein G
chr11_-_115419917 0.13 ENSMUST00000106537.1
ENSMUST00000043931.2
ENSMUST00000073791.3
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit d
chr6_+_63255971 0.13 ENSMUST00000159561.1
ENSMUST00000095852.3
glutamate receptor, ionotropic, delta 2
chr19_-_32196393 0.13 ENSMUST00000151822.1
sphingomyelin synthase 1
chr17_-_45599603 0.12 ENSMUST00000171847.1
ENSMUST00000166633.1
ENSMUST00000169729.1
solute carrier family 29 (nucleoside transporters), member 1
chr15_+_81744848 0.12 ENSMUST00000109554.1
zinc finger CCCH type containing 7B
chr5_+_115279666 0.12 ENSMUST00000040421.4
coenzyme Q5 homolog, methyltransferase (yeast)
chr11_+_113684412 0.12 ENSMUST00000042227.8
ENSMUST00000123466.1
ENSMUST00000106621.3
DNA segment, Chr 11, Wayne State University 47, expressed
chr3_+_32436151 0.12 ENSMUST00000029201.7
phosphatidylinositol 3-kinase, catalytic, alpha polypeptide
chr16_-_44333135 0.12 ENSMUST00000047446.6
SID1 transmembrane family, member 1
chr13_+_4233730 0.12 ENSMUST00000081326.6
aldo-keto reductase family 1, member C19
chr3_-_41742471 0.12 ENSMUST00000026866.8
sodium channel and clathrin linker 1
chr11_-_102185202 0.12 ENSMUST00000107156.2
LSM12 homolog (S. cerevisiae)
chr14_+_57999305 0.12 ENSMUST00000180534.1
RIKEN cDNA 3110083C13 gene
chr9_-_49798905 0.12 ENSMUST00000114476.2
neural cell adhesion molecule 1
chr17_+_37492468 0.12 ENSMUST00000168318.1
olfactory receptor 110
chr13_-_3918157 0.11 ENSMUST00000091853.4
neuroepithelial cell transforming gene 1
chr9_+_66946057 0.11 ENSMUST00000040917.7
ENSMUST00000127896.1
ribosomal protein S27-like
chr5_+_107900502 0.11 ENSMUST00000082223.6
ribosomal protein L5
chr2_-_34913976 0.11 ENSMUST00000028232.3
PHD finger protein 19
chr11_-_94297067 0.11 ENSMUST00000132623.2
LUC7-like 3 (S. cerevisiae)
chr8_-_3625274 0.11 ENSMUST00000004749.6
Purkinje cell protein 2 (L7)
chr3_+_54755574 0.11 ENSMUST00000029371.2
SMAD family member 9
chr3_-_96905294 0.11 ENSMUST00000029738.7
G protein-coupled receptor 89
chr4_+_15881255 0.11 ENSMUST00000029876.1
calbindin 1
chrM_+_8600 0.11 ENSMUST00000082409.1
mitochondrially encoded cytochrome c oxidase III
chr9_+_65361049 0.11 ENSMUST00000147185.1
predicted gene 514
chr2_-_37647199 0.11 ENSMUST00000028279.3
spermatid perinuclear RNA binding protein
chr11_-_74724670 0.10 ENSMUST00000021091.8
platelet-activating factor acetylhydrolase, isoform 1b, subunit 1
chr10_+_127420867 0.10 ENSMUST00000064793.6
R3H domain containing 2
chrM_+_10167 0.10 ENSMUST00000082414.1
mitochondrially encoded NADH dehydrogenase 4
chr5_+_21737141 0.10 ENSMUST00000030882.5
peptidase (mitochondrial processing) beta
chr5_-_146795002 0.10 ENSMUST00000085614.5
ubiquitin specific peptidase 12
chr9_+_92457369 0.10 ENSMUST00000034941.7
phospholipid scramblase 4
chr5_+_45493374 0.10 ENSMUST00000046122.6
leucine aminopeptidase 3
chr1_-_144177259 0.10 ENSMUST00000111941.1
ENSMUST00000052375.1
regulator of G-protein signaling 13
chr3_+_32436376 0.10 ENSMUST00000108242.1
phosphatidylinositol 3-kinase, catalytic, alpha polypeptide
chr11_-_99230998 0.10 ENSMUST00000103133.3
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1
chr10_-_6980376 0.10 ENSMUST00000105617.1
interaction protein for cytohesin exchange factors 1
chr3_-_141982224 0.10 ENSMUST00000029948.8
bone morphogenetic protein receptor, type 1B
chr9_-_44802951 0.09 ENSMUST00000044694.6
tetratricopeptide repeat domain 36
chr17_-_32822200 0.09 ENSMUST00000179695.1
zinc finger protein 799
chr15_-_100424092 0.09 ENSMUST00000154676.1
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2

Network of associatons between targets according to the STRING database.

First level regulatory network of Prrx1_Isx_Prrxl1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.3 GO:0000707 meiotic DNA recombinase assembly(GO:0000707)
0.2 0.5 GO:0009106 lipoate metabolic process(GO:0009106)
0.2 0.5 GO:0006059 hexitol metabolic process(GO:0006059)
0.1 0.3 GO:0009162 deoxyribonucleoside monophosphate metabolic process(GO:0009162)
0.1 0.4 GO:0016062 adaptation of rhodopsin mediated signaling(GO:0016062) light adaption(GO:0036367)
0.1 0.3 GO:0045726 positive regulation of integrin biosynthetic process(GO:0045726)
0.1 0.4 GO:0043985 histone H4-R3 methylation(GO:0043985)
0.1 0.6 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560)
0.1 0.8 GO:2000253 adult feeding behavior(GO:0008343) positive regulation of feeding behavior(GO:2000253)
0.1 0.2 GO:0044028 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.1 0.2 GO:1904976 response to bleomycin(GO:1904975) cellular response to bleomycin(GO:1904976)
0.1 3.6 GO:0006284 base-excision repair(GO:0006284)
0.1 1.1 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.1 0.4 GO:0001757 somite specification(GO:0001757)
0.1 0.2 GO:0045077 CD4-positive, CD25-positive, alpha-beta regulatory T cell lineage commitment(GO:0002362) negative regulation of histone deacetylation(GO:0031064) positive regulation of CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0032831) negative regulation of interferon-gamma biosynthetic process(GO:0045077)
0.1 0.6 GO:0007342 fusion of sperm to egg plasma membrane(GO:0007342)
0.1 0.3 GO:1990034 calcium ion export from cell(GO:1990034)
0.1 0.3 GO:0042776 response to glucagon(GO:0033762) mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.1 0.8 GO:0000076 DNA replication checkpoint(GO:0000076)
0.1 0.2 GO:2000229 pancreatic stellate cell proliferation(GO:0072343) regulation of pancreatic stellate cell proliferation(GO:2000229)
0.0 0.5 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.5 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.0 0.3 GO:0045918 negative regulation of cytolysis(GO:0045918)
0.0 0.4 GO:0006265 DNA topological change(GO:0006265)
0.0 0.4 GO:0031339 negative regulation of vesicle fusion(GO:0031339)
0.0 0.1 GO:0017187 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.0 0.2 GO:0002188 translation reinitiation(GO:0002188)
0.0 0.2 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.0 0.3 GO:0016056 rhodopsin mediated signaling pathway(GO:0016056)
0.0 0.1 GO:1903632 positive regulation of aminoacyl-tRNA ligase activity(GO:1903632)
0.0 0.2 GO:1903587 negative regulation of peptidyl-serine dephosphorylation(GO:1902309) regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903587)
0.0 0.1 GO:2000870 regulation of progesterone secretion(GO:2000870)
0.0 0.6 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.0 0.7 GO:0070050 neuron cellular homeostasis(GO:0070050)
0.0 0.1 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.0 0.8 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.2 GO:0043137 DNA replication, Okazaki fragment processing(GO:0033567) DNA replication, removal of RNA primer(GO:0043137)
0.0 0.3 GO:0033227 dsRNA transport(GO:0033227)
0.0 0.4 GO:0071044 histone mRNA catabolic process(GO:0071044)
0.0 0.1 GO:1903232 melanosome assembly(GO:1903232)
0.0 0.1 GO:0045360 regulation of interleukin-1 biosynthetic process(GO:0045360) positive regulation of interleukin-1 biosynthetic process(GO:0045362)
0.0 0.1 GO:0010615 positive regulation of cardiac muscle adaptation(GO:0010615) positive regulation of cardiac muscle hypertrophy in response to stress(GO:1903244)
0.0 0.2 GO:0014045 establishment of endothelial blood-brain barrier(GO:0014045)
0.0 0.2 GO:0031642 negative regulation of myelination(GO:0031642)
0.0 0.1 GO:0001878 response to yeast(GO:0001878) modulation by symbiont of host molecular function(GO:0052055) modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422)
0.0 0.1 GO:0046341 CDP-diacylglycerol metabolic process(GO:0046341)
0.0 0.9 GO:0006958 complement activation, classical pathway(GO:0006958)
0.0 0.2 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.3 GO:0046642 negative regulation of alpha-beta T cell proliferation(GO:0046642)
0.0 0.2 GO:0021847 ventricular zone neuroblast division(GO:0021847)
0.0 0.3 GO:0070262 peptidyl-serine dephosphorylation(GO:0070262)
0.0 0.1 GO:0044268 multicellular organismal protein metabolic process(GO:0044268)
0.0 0.1 GO:0002322 B cell proliferation involved in immune response(GO:0002322)
0.0 0.1 GO:0014816 skeletal muscle satellite cell differentiation(GO:0014816)
0.0 0.1 GO:0098734 protein depalmitoylation(GO:0002084) negative regulation of Golgi to plasma membrane protein transport(GO:0042997) negative regulation of establishment of protein localization to plasma membrane(GO:0090005) macromolecule depalmitoylation(GO:0098734)
0.0 0.2 GO:0072615 interleukin-17 secretion(GO:0072615)
0.0 0.1 GO:0051661 maintenance of centrosome location(GO:0051661)
0.0 0.1 GO:0090309 positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.0 0.1 GO:0023016 signal transduction by trans-phosphorylation(GO:0023016)
0.0 0.1 GO:0061153 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.0 0.1 GO:0048165 ovarian cumulus expansion(GO:0001550) fused antrum stage(GO:0048165)
0.0 0.1 GO:1905244 regulation of modification of synaptic structure(GO:1905244)
0.0 0.2 GO:0010650 positive regulation of cell communication by electrical coupling(GO:0010650) positive regulation of membrane depolarization during cardiac muscle cell action potential(GO:1900827)
0.0 1.1 GO:0042773 ATP synthesis coupled electron transport(GO:0042773)
0.0 0.2 GO:0042118 endothelial cell activation(GO:0042118)
0.0 0.1 GO:2001160 regulation of histone H3-K79 methylation(GO:2001160)
0.0 0.1 GO:0015862 uridine transport(GO:0015862)
0.0 0.1 GO:0001887 selenium compound metabolic process(GO:0001887) selenocysteine metabolic process(GO:0016259)
0.0 0.4 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.1 GO:0046294 formaldehyde catabolic process(GO:0046294)
0.0 0.2 GO:0043922 negative regulation by host of viral transcription(GO:0043922)
0.0 0.1 GO:0051387 negative regulation of neurotrophin TRK receptor signaling pathway(GO:0051387)
0.0 0.1 GO:0061087 positive regulation of histone H3-K27 methylation(GO:0061087)
0.0 0.0 GO:0042450 arginine biosynthetic process via ornithine(GO:0042450)
0.0 0.1 GO:0001880 Mullerian duct regression(GO:0001880)
0.0 0.1 GO:0090043 regulation of tubulin deacetylation(GO:0090043)
0.0 0.1 GO:1901162 serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162)
0.0 0.1 GO:0045162 clustering of voltage-gated sodium channels(GO:0045162)
0.0 0.4 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.3 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 0.5 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 0.1 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.1 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.7 GO:0071300 cellular response to retinoic acid(GO:0071300)
0.0 0.1 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.0 0.1 GO:0015851 nucleobase transport(GO:0015851) pyrimidine nucleobase transport(GO:0015855)
0.0 0.1 GO:1904861 excitatory synapse assembly(GO:1904861)
0.0 0.4 GO:0006767 water-soluble vitamin metabolic process(GO:0006767)
0.0 0.1 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.0 0.0 GO:0060467 negative regulation of fertilization(GO:0060467)
0.0 0.1 GO:1900170 negative regulation of glucocorticoid mediated signaling pathway(GO:1900170)
0.0 0.0 GO:1904879 positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel(GO:1904879)
0.0 0.6 GO:0002181 cytoplasmic translation(GO:0002181)
0.0 0.3 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 0.1 GO:0060011 follicle-stimulating hormone signaling pathway(GO:0042699) Sertoli cell proliferation(GO:0060011)
0.0 1.0 GO:0032414 positive regulation of ion transmembrane transporter activity(GO:0032414)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.6 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.3 1.3 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)
0.1 0.5 GO:0097454 Schwann cell microvillus(GO:0097454)
0.1 0.6 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.1 0.8 GO:0005796 Golgi lumen(GO:0005796)
0.1 0.6 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.1 0.2 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.1 0.3 GO:0033165 interphotoreceptor matrix(GO:0033165)
0.1 0.4 GO:1990357 terminal web(GO:1990357)
0.0 0.5 GO:0034709 methylosome(GO:0034709)
0.0 0.3 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.0 0.3 GO:0005687 U4 snRNP(GO:0005687)
0.0 0.4 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 0.4 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750)
0.0 0.3 GO:0071438 invadopodium membrane(GO:0071438)
0.0 0.3 GO:0030478 actin cap(GO:0030478)
0.0 0.2 GO:0031298 replication fork protection complex(GO:0031298)
0.0 0.2 GO:0030891 VCB complex(GO:0030891)
0.0 0.5 GO:0097539 ciliary transition fiber(GO:0097539)
0.0 0.4 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.0 0.4 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 1.5 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.5 GO:0043205 microfibril(GO:0001527) fibril(GO:0043205)
0.0 0.2 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.0 0.1 GO:0000125 PCAF complex(GO:0000125)
0.0 0.7 GO:0002080 acrosomal membrane(GO:0002080)
0.0 0.1 GO:0008623 CHRAC(GO:0008623)
0.0 1.1 GO:0032154 cleavage furrow(GO:0032154) cell surface furrow(GO:0097610)
0.0 0.1 GO:0000814 ESCRT II complex(GO:0000814)
0.0 0.1 GO:0000235 astral microtubule(GO:0000235)
0.0 0.4 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 1.3 GO:0070469 respiratory chain(GO:0070469)
0.0 0.2 GO:0046581 intercellular canaliculus(GO:0046581)
0.0 0.1 GO:0098837 postsynaptic recycling endosome(GO:0098837)
0.0 0.2 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.7 GO:0008023 transcription elongation factor complex(GO:0008023)
0.0 0.1 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 0.1 GO:0005955 calcineurin complex(GO:0005955)
0.0 0.0 GO:0005584 collagen type I trimer(GO:0005584)
0.0 0.1 GO:0000138 Golgi trans cisterna(GO:0000138)
0.0 0.7 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.3 GO:0005614 interstitial matrix(GO:0005614)
0.0 0.5 GO:0043034 costamere(GO:0043034)
0.0 0.1 GO:0070847 core mediator complex(GO:0070847)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.6 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.2 1.3 GO:0000150 recombinase activity(GO:0000150)
0.2 0.5 GO:0019150 D-ribulokinase activity(GO:0019150)
0.1 0.5 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.1 0.5 GO:0030023 extracellular matrix constituent conferring elasticity(GO:0030023)
0.1 0.6 GO:0016728 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.1 0.4 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.1 0.6 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.1 1.1 GO:0051378 serotonin binding(GO:0051378)
0.1 0.5 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.1 0.5 GO:0004126 cytidine deaminase activity(GO:0004126)
0.1 0.4 GO:0003917 DNA topoisomerase type I activity(GO:0003917)
0.1 0.6 GO:0086080 protein binding involved in heterotypic cell-cell adhesion(GO:0086080)
0.1 0.3 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.1 0.5 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.1 0.2 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.1 0.4 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.1 0.6 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 0.4 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.3 GO:0051033 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.0 0.2 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.0 0.1 GO:0016748 succinyltransferase activity(GO:0016748)
0.0 1.3 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.2 GO:0008142 oxysterol binding(GO:0008142)
0.0 0.1 GO:0070052 collagen V binding(GO:0070052)
0.0 0.3 GO:1990446 U1 snRNP binding(GO:1990446)
0.0 0.1 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
0.0 0.2 GO:0005499 vitamin D binding(GO:0005499)
0.0 0.8 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.2 GO:0042296 ISG15 transferase activity(GO:0042296)
0.0 0.1 GO:0016314 phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase activity(GO:0016314)
0.0 0.2 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.0 0.1 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.3 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.2 GO:0070180 large ribosomal subunit rRNA binding(GO:0070180)
0.0 0.1 GO:0018738 S-formylglutathione hydrolase activity(GO:0018738)
0.0 0.1 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.0 0.2 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.0 0.1 GO:0003998 acylphosphatase activity(GO:0003998)
0.0 0.2 GO:0052813 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0 0.6 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.1 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.0 0.5 GO:0070064 proline-rich region binding(GO:0070064)
0.0 0.1 GO:0055104 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.0 0.4 GO:0048156 tau protein binding(GO:0048156)
0.0 0.4 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.1 GO:0043758 acetate-CoA ligase (ADP-forming) activity(GO:0043758)
0.0 0.0 GO:0005550 pheromone binding(GO:0005550)
0.0 0.1 GO:0038049 glucocorticoid receptor activity(GO:0004883) transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.0 0.3 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds(GO:0016799)
0.0 0.2 GO:0050544 arachidonic acid binding(GO:0050544)
0.0 0.1 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.0 0.4 GO:0003785 actin monomer binding(GO:0003785)
0.0 0.1 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.2 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.1 GO:0016316 phosphatidylinositol-3,4-bisphosphate 4-phosphatase activity(GO:0016316)
0.0 0.1 GO:0008494 translation activator activity(GO:0008494)
0.0 1.9 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.1 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.1 GO:0045340 NAD(P)H oxidase activity(GO:0016174) mercury ion binding(GO:0045340)
0.0 0.0 GO:0016743 carboxyl- or carbamoyltransferase activity(GO:0016743)
0.0 0.0 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.0 0.1 GO:0016918 retinal binding(GO:0016918)
0.0 0.1 GO:0015254 purine nucleobase transmembrane transporter activity(GO:0005345) pyrimidine nucleobase transmembrane transporter activity(GO:0005350) nucleobase transmembrane transporter activity(GO:0015205) glycerol channel activity(GO:0015254)
0.0 0.1 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 0.1 GO:0051525 NFAT protein binding(GO:0051525)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 3.8 PID IL4 2PATHWAY IL4-mediated signaling events
0.0 1.0 PID ATR PATHWAY ATR signaling pathway
0.0 0.6 PID MYC PATHWAY C-MYC pathway
0.0 0.4 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 1.1 PID E2F PATHWAY E2F transcription factor network
0.0 0.2 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.6 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 1.1 REACTOME LIGAND GATED ION CHANNEL TRANSPORT Genes involved in Ligand-gated ion channel transport
0.0 0.3 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 1.0 REACTOME MYOGENESIS Genes involved in Myogenesis
0.0 0.7 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 1.4 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.9 REACTOME G1 PHASE Genes involved in G1 Phase
0.0 1.0 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.1 REACTOME DARPP 32 EVENTS Genes involved in DARPP-32 events
0.0 0.1 REACTOME HORMONE LIGAND BINDING RECEPTORS Genes involved in Hormone ligand-binding receptors
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE EARLY ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the early endosome membrane
0.0 0.5 REACTOME IL RECEPTOR SHC SIGNALING Genes involved in Interleukin receptor SHC signaling
0.0 0.4 REACTOME METABOLISM OF STEROID HORMONES AND VITAMINS A AND D Genes involved in Metabolism of steroid hormones and vitamins A and D
0.0 0.8 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.7 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 1.3 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production