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2D miR_HR1_12

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Results for Hoxc9

Z-value: 0.52

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Transcription factors associated with Hoxc9

Gene Symbol Gene ID Gene Info
ENSMUSG00000036139.6 homeobox C9

Activity profile of Hoxc9 motif

Sorted Z-values of Hoxc9 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr4_-_137118135 1.03 ENSMUST00000154285.1
predicted gene 13001
chr5_+_20702129 0.71 ENSMUST00000101556.4
membrane associated guanylate kinase, WW and PDZ domain containing 2
chrX_+_49463926 0.64 ENSMUST00000130558.1
Rho GTPase activating protein 36
chr7_+_131032061 0.57 ENSMUST00000084509.3
deleted in malignant brain tumors 1
chr1_-_45503282 0.51 ENSMUST00000086430.4
collagen, type V, alpha 2
chr11_-_100193246 0.48 ENSMUST00000059707.2
keratin 9
chr2_+_91082362 0.44 ENSMUST00000169852.1
spleen focus forming virus (SFFV) proviral integration oncogene
chr11_+_98664341 0.41 ENSMUST00000017348.2
gasdermin A
chr4_+_136143497 0.40 ENSMUST00000008016.2
inhibitor of DNA binding 3
chr18_+_82855894 0.34 ENSMUST00000181345.1
ENSMUST00000180631.1
RIKEN cDNA 4930445N18 gene
chr4_+_100776664 0.33 ENSMUST00000030257.8
ENSMUST00000097955.2
cache domain containing 1
chr4_+_33924632 0.27 ENSMUST00000057188.6
cannabinoid receptor 1 (brain)
chr17_-_57000018 0.26 ENSMUST00000002740.2
persephin
chr4_+_150997081 0.26 ENSMUST00000030803.1
urotensin 2
chr8_+_54954728 0.23 ENSMUST00000033915.7
glycoprotein m6a
chr13_+_94083490 0.19 ENSMUST00000156071.1
lipoma HMGIC fusion partner-like 2
chr13_+_58281183 0.18 ENSMUST00000180882.1
ENSMUST00000180452.1
predicted gene, 26555
chr5_+_102768771 0.15 ENSMUST00000112852.1
Rho GTPase activating protein 24
chr11_-_101894355 0.14 ENSMUST00000057054.7
mesenchyme homeobox 1
chr1_+_60909148 0.13 ENSMUST00000097720.3
cytotoxic T-lymphocyte-associated protein 4
chrX_+_56609751 0.12 ENSMUST00000144068.1
solute carrier family 9 (sodium/hydrogen exchanger), member 6
chr8_+_118283719 0.11 ENSMUST00000117160.1
cadherin 13
chr6_-_99044414 0.11 ENSMUST00000177507.1
ENSMUST00000123992.1
forkhead box P1
chr2_+_4300462 0.11 ENSMUST00000175669.1
FERM domain containing 4A
chr6_-_55133014 0.11 ENSMUST00000003568.8
corticotropin releasing hormone receptor 2
chr8_-_120228221 0.11 ENSMUST00000183235.1
RIKEN cDNA A330074K22 gene
chr6_+_125145235 0.11 ENSMUST00000119527.1
ENSMUST00000088276.6
ENSMUST00000051171.7
ENSMUST00000117675.1
intermediate filament family orphan 1
chr12_-_15816762 0.10 ENSMUST00000020922.7
tribbles homolog 2 (Drosophila)
chr14_+_80000292 0.10 ENSMUST00000088735.3
olfactomedin 4
chrX_-_141474034 0.09 ENSMUST00000101205.2
collagen, type IV, alpha 6
chr18_+_65582390 0.08 ENSMUST00000169679.1
ENSMUST00000183326.1
zinc finger protein 532
chr5_-_67427794 0.08 ENSMUST00000169190.1
BEN domain containing 4
chr10_+_5593718 0.08 ENSMUST00000051809.8
myc target 1
chr1_+_60908993 0.08 ENSMUST00000027164.2
cytotoxic T-lymphocyte-associated protein 4
chr10_+_52391606 0.07 ENSMUST00000067085.4
nephrocan
chr15_-_55113460 0.07 ENSMUST00000100659.2
ENSMUST00000110230.1
predicted gene 9920
chr4_+_144893127 0.07 ENSMUST00000142808.1
dehydrogenase/reductase (SDR family) member 3
chr4_-_109202217 0.07 ENSMUST00000160774.1
ENSMUST00000030288.7
ENSMUST00000162787.2
oxysterol binding protein-like 9
chr13_+_113209659 0.07 ENSMUST00000038144.8
endothelial cell-specific molecule 1
chr2_+_126034967 0.06 ENSMUST00000110442.1
fibroblast growth factor 7
chrX_-_18461371 0.06 ENSMUST00000044188.4
RIKEN cDNA 4930578C19 gene
chr2_+_91256144 0.06 ENSMUST00000154959.1
ENSMUST00000059566.4
protein kinase C and casein kinase substrate in neurons 3
chr11_-_98022594 0.06 ENSMUST00000103144.3
ENSMUST00000017552.6
ENSMUST00000092736.4
ENSMUST00000107562.1
calcium channel, voltage-dependent, beta 1 subunit
chr11_-_94242701 0.05 ENSMUST00000061469.3
WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2
chr7_-_139582790 0.05 ENSMUST00000106095.2
NK6 homeobox 2
chr6_+_116650674 0.05 ENSMUST00000067354.5
ENSMUST00000178241.1
RIKEN cDNA 8430408G22 gene
chr16_-_37384915 0.05 ENSMUST00000114787.1
ENSMUST00000114782.1
ENSMUST00000023526.2
ENSMUST00000114775.1
syntaxin binding protein 5-like
chr6_+_52177498 0.05 ENSMUST00000070587.3
RIKEN cDNA 5730596B20 gene
chr18_+_65582239 0.05 ENSMUST00000182684.1
zinc finger protein 532
chr4_-_150003130 0.04 ENSMUST00000084117.6
hexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase)
chr9_+_35423582 0.04 ENSMUST00000154652.1
cell adhesion molecule-related/down-regulated by oncogenes
chr2_+_102658640 0.04 ENSMUST00000080210.3
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr1_+_66321708 0.04 ENSMUST00000114013.1
microtubule-associated protein 2
chr17_-_40914350 0.04 ENSMUST00000166343.1
glycine-N-acyltransferase-like 3
chr19_+_22448242 0.04 ENSMUST00000037901.6
transient receptor potential cation channel, subfamily M, member 3
chr17_-_49564262 0.03 ENSMUST00000057610.6
dishevelled associated activator of morphogenesis 2
chr9_-_7835255 0.03 ENSMUST00000074246.6
baculoviral IAP repeat-containing 2
chr16_-_29946499 0.03 ENSMUST00000181968.1
predicted gene, 26569
chr9_+_121710389 0.03 ENSMUST00000035113.9
differentially expressed in B16F10 1
chr6_-_119388671 0.03 ENSMUST00000169744.1
adiponectin receptor 2
chrX_+_56609843 0.03 ENSMUST00000077741.5
ENSMUST00000114784.2
solute carrier family 9 (sodium/hydrogen exchanger), member 6
chr13_+_89540636 0.03 ENSMUST00000022108.7
hyaluronan and proteoglycan link protein 1
chrX_-_103186618 0.03 ENSMUST00000121720.1
nucleosome assembly protein 1-like 2
chr2_+_126034647 0.02 ENSMUST00000064794.7
fibroblast growth factor 7
chr5_-_44101668 0.02 ENSMUST00000087441.4
ENSMUST00000074113.6
prominin 1
chr4_+_107830958 0.01 ENSMUST00000106731.2
low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
chr5_+_67260696 0.01 ENSMUST00000161233.1
ENSMUST00000160352.1
transmembrane protein 33
chr5_+_67260565 0.01 ENSMUST00000037918.5
ENSMUST00000162543.1
transmembrane protein 33
chr10_-_13324250 0.01 ENSMUST00000105543.1
phosphatase and actin regulator 2
chr16_-_37384940 0.00 ENSMUST00000114781.1
ENSMUST00000114780.1
syntaxin binding protein 5-like
chr1_-_74284636 0.00 ENSMUST00000178235.1
ENSMUST00000006462.7
angio-associated migratory protein
chr2_-_128967725 0.00 ENSMUST00000099385.2
predicted gene 10762
chr4_+_137594140 0.00 ENSMUST00000105840.1
ENSMUST00000055131.6
ENSMUST00000105839.1
ENSMUST00000105838.1
ubiquitin specific peptidase 48
chr1_+_74284930 0.00 ENSMUST00000113805.1
ENSMUST00000027370.6
ENSMUST00000087226.4
paroxysmal nonkinesiogenic dyskinesia

Network of associatons between targets according to the STRING database.

First level regulatory network of Hoxc9

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.1 0.4 GO:0045347 negative regulation of MHC class II biosynthetic process(GO:0045347)
0.1 0.3 GO:0046005 positive regulation of circadian sleep/wake cycle, wakefulness(GO:0010841) positive regulation of circadian sleep/wake cycle, REM sleep(GO:0046005)
0.1 0.7 GO:0097118 neuroligin clustering involved in postsynaptic membrane assembly(GO:0097118)
0.1 0.3 GO:0099552 trans-synaptic signaling by lipid, modulating synaptic transmission(GO:0099552) trans-synaptic signaling by endocannabinoid, modulating synaptic transmission(GO:0099553)
0.0 0.2 GO:0045590 negative regulation of regulatory T cell differentiation(GO:0045590)
0.0 0.1 GO:0033685 negative regulation of luteinizing hormone secretion(GO:0033685)
0.0 0.1 GO:0061056 sclerotome development(GO:0061056)
0.0 0.1 GO:0042091 interleukin-10 biosynthetic process(GO:0042091) regulation of interleukin-10 biosynthetic process(GO:0045074)
0.0 0.6 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.1 GO:0061033 secretion by lung epithelial cell involved in lung growth(GO:0061033)
0.0 0.1 GO:0055095 lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096)
0.0 0.2 GO:0031547 brain-derived neurotrophic factor receptor signaling pathway(GO:0031547)
0.0 0.1 GO:1902202 regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.0 0.2 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)
0.0 0.4 GO:0030903 notochord development(GO:0030903)
0.0 0.1 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.0 0.0 GO:1902524 positive regulation of protein K48-linked ubiquitination(GO:1902524) positive regulation of protein monoubiquitination(GO:1902527)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0005588 collagen type V trimer(GO:0005588)
0.1 0.6 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.0 0.7 GO:0036056 filtration diaphragm(GO:0036056) slit diaphragm(GO:0036057)
0.0 0.2 GO:0044308 axonal spine(GO:0044308)
0.0 0.5 GO:0045095 keratin filament(GO:0045095)
0.0 0.1 GO:0098651 collagen type IV trimer(GO:0005587) network-forming collagen trimer(GO:0098642) collagen network(GO:0098645) basement membrane collagen trimer(GO:0098651)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0070699 type II activin receptor binding(GO:0070699)
0.1 0.3 GO:0004949 cannabinoid receptor activity(GO:0004949)
0.0 0.4 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.1 GO:0043404 corticotrophin-releasing factor receptor activity(GO:0015056) corticotropin-releasing hormone receptor activity(GO:0043404)
0.0 0.1 GO:0055100 adiponectin binding(GO:0055100)
0.0 0.1 GO:0005171 hepatocyte growth factor receptor binding(GO:0005171)
0.0 0.1 GO:0005111 type 2 fibroblast growth factor receptor binding(GO:0005111)
0.0 0.0 GO:0047936 glucose 1-dehydrogenase [NAD(P)] activity(GO:0047936)
0.0 0.2 GO:0015386 potassium:proton antiporter activity(GO:0015386)
0.0 0.5 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.6 GO:0005044 scavenger receptor activity(GO:0005044)
0.0 0.0 GO:0098770 FBXO family protein binding(GO:0098770)
0.0 0.1 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 NABA COLLAGENS Genes encoding collagen proteins

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 REACTOME NEPHRIN INTERACTIONS Genes involved in Nephrin interactions
0.0 0.8 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions