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2D miR_HR1_12

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Results for Sox17

Z-value: 0.47

Motif logo

Transcription factors associated with Sox17

Gene Symbol Gene ID Gene Info
ENSMUSG00000025902.7 SRY (sex determining region Y)-box 17

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Sox17mm10_v2_chr1_-_4496363_44963890.136.9e-01Click!

Activity profile of Sox17 motif

Sorted Z-values of Sox17 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr6_-_148944750 0.68 ENSMUST00000111562.1
ENSMUST00000081956.5
family with sequence similarity 60, member A
chr4_-_42773993 0.64 ENSMUST00000095114.4
chemokine (C-C motif) ligand 21A (serine)
chr2_-_127133909 0.63 ENSMUST00000110387.3
non-SMC condensin I complex, subunit H
chr5_-_107597577 0.51 ENSMUST00000100949.3
ENSMUST00000078021.6
glomulin, FKBP associated protein
chr12_+_24708241 0.48 ENSMUST00000020980.5
ribonucleotide reductase M2
chr16_-_18413452 0.48 ENSMUST00000165430.1
ENSMUST00000147720.1
catechol-O-methyltransferase
chr4_+_138775735 0.45 ENSMUST00000030528.2
phospholipase A2, group IID
chr4_+_41903610 0.45 ENSMUST00000098128.3
predicted gene, 21541
chr5_-_89457763 0.40 ENSMUST00000049209.8
group specific component
chr9_+_57521232 0.40 ENSMUST00000000090.6
cytochrome c oxidase subunit Va
chr12_+_51348265 0.39 ENSMUST00000119211.1
G2/M-phase specific E3 ubiquitin ligase
chr18_-_33213766 0.39 ENSMUST00000119991.1
ENSMUST00000118990.1
StAR-related lipid transfer (START) domain containing 4
chr8_-_105471481 0.39 ENSMUST00000014990.6
tubulin polymerization-promoting protein family member 3
chr12_+_51348370 0.36 ENSMUST00000121521.1
G2/M-phase specific E3 ubiquitin ligase
chr6_+_121245903 0.34 ENSMUST00000032198.9
ubiquitin specific peptidase 18
chr12_+_51348019 0.31 ENSMUST00000054308.6
G2/M-phase specific E3 ubiquitin ligase
chr12_-_84400851 0.30 ENSMUST00000117286.1
ectonucleoside triphosphate diphosphohydrolase 5
chr13_+_54071815 0.29 ENSMUST00000021930.8
sideroflexin 1
chr9_+_66946057 0.28 ENSMUST00000040917.7
ENSMUST00000127896.1
ribosomal protein S27-like
chr15_+_74721193 0.27 ENSMUST00000070923.1
thioesterase superfamily member 6
chr14_+_31134853 0.27 ENSMUST00000090212.4
5'-nucleotidase domain containing 2
chr5_-_130002838 0.27 ENSMUST00000111308.1
ENSMUST00000111307.1
glucuronidase, beta
chr14_+_73142591 0.27 ENSMUST00000170368.1
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
chr12_-_84400929 0.27 ENSMUST00000122194.1
ectonucleoside triphosphate diphosphohydrolase 5
chr5_-_125434048 0.26 ENSMUST00000169485.1
DEAH (Asp-Glu-Ala-His) box polypeptide 37
chr5_-_107597533 0.26 ENSMUST00000124140.1
glomulin, FKBP associated protein
chr2_+_18677002 0.26 ENSMUST00000028071.6
Bmi1 polycomb ring finger oncogene
chr6_+_83034173 0.25 ENSMUST00000000707.2
ENSMUST00000101257.3
lysyl oxidase-like 3
chr6_+_87104744 0.23 ENSMUST00000170124.2
DNA segment, Chr 6, ERATO Doi 527, expressed
chr13_-_74376566 0.23 ENSMUST00000091481.2
zinc finger protein 72
chr18_-_33213832 0.22 ENSMUST00000025236.2
StAR-related lipid transfer (START) domain containing 4
chrX_+_48695004 0.22 ENSMUST00000033433.2
RNA binding motif protein, X-linked 2
chr2_+_181187247 0.22 ENSMUST00000016488.6
ENSMUST00000108841.1
pancreatic progenitor cell differentiation and proliferation factor homolog (zebrafish)RIKEN cDNA 2700038C09 gene
chr3_-_158016419 0.21 ENSMUST00000127778.1
serine/arginine-rich splicing factor 11
chr9_+_82829806 0.20 ENSMUST00000113245.2
ENSMUST00000034783.4
interleukin-1 receptor-associated kinase 1 binding protein 1
chr14_+_73142490 0.20 ENSMUST00000170370.1
ENSMUST00000164822.1
ENSMUST00000165429.1
regulator of chromosome condensation (RCC1) and BTB (POZ) domain containing protein 2
chr2_-_15049254 0.19 ENSMUST00000028034.8
ENSMUST00000114713.1
NOL1/NOP2/Sun domain family member 6
chr9_+_3335470 0.18 ENSMUST00000053407.5
alkB, alkylation repair homolog 8 (E. coli)
chr17_+_47759175 0.17 ENSMUST00000125177.1
transcription factor EB
chr10_+_80249106 0.16 ENSMUST00000105364.1
NADH dehydrogenase (ubiquinone) Fe-S protein 7
chr1_+_52008210 0.16 ENSMUST00000027277.5
signal transducer and activator of transcription 4
chr11_-_51606840 0.16 ENSMUST00000074669.3
ENSMUST00000101249.2
ENSMUST00000109103.3
heterogeneous nuclear ribonucleoprotein A/B
chr16_+_38362205 0.16 ENSMUST00000023494.6
popeye domain containing 2
chr12_+_84970897 0.15 ENSMUST00000021669.8
ENSMUST00000171040.1
FCF1 small subunit (SSU) processome component homolog (S. cerevisiae)
chr2_-_110950923 0.14 ENSMUST00000099623.3
anoctamin 3
chr4_-_135971894 0.13 ENSMUST00000105852.1
lysophospholipase 2
chr9_+_50494516 0.13 ENSMUST00000114474.1
RIKEN cDNA 1600029D21 gene
chr10_-_59221757 0.13 ENSMUST00000165971.1
septin 10
chr2_+_52857844 0.12 ENSMUST00000090952.4
ENSMUST00000049483.6
ENSMUST00000050719.6
formin-like 2
chr2_-_66410064 0.12 ENSMUST00000112366.1
sodium channel, voltage-gated, type I, alpha
chr11_-_11970540 0.12 ENSMUST00000109653.1
growth factor receptor bound protein 10
chr19_+_6184363 0.12 ENSMUST00000025699.2
ENSMUST00000113528.1
RIKEN cDNA 1700123I01 gene
chr9_-_48605147 0.11 ENSMUST00000034808.5
ENSMUST00000119426.1
nicotinamide N-methyltransferase
chr8_+_69822429 0.11 ENSMUST00000164890.1
ENSMUST00000034325.4
lysophosphatidic acid receptor 2
chr1_+_178256103 0.11 ENSMUST00000069568.3
predicted gene 9982
chr13_-_35027077 0.11 ENSMUST00000170538.1
ENSMUST00000163280.1
enoyl-Coenzyme A delta isomerase 2
chr10_+_93453382 0.10 ENSMUST00000016033.7
leukotriene A4 hydrolase
chr6_-_87690819 0.10 ENSMUST00000162547.1
Riken cDNA 1810020O05 gene
chr16_-_23029062 0.10 ENSMUST00000115349.2
kininogen 2
chr3_+_101377074 0.10 ENSMUST00000043983.5
immunoglobulin superfamily, member 3
chr8_-_85380964 0.10 ENSMUST00000122452.1
myosin light chain kinase 3
chr2_-_57113053 0.09 ENSMUST00000112627.1
nuclear receptor subfamily 4, group A, member 2
chr4_-_156200818 0.09 ENSMUST00000085425.4
ISG15 ubiquitin-like modifier
chr11_+_98646755 0.09 ENSMUST00000093938.3
ENSMUST00000017355.5
gasdermin A2
chr7_+_97400003 0.09 ENSMUST00000032882.8
NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 2
chr16_+_38362234 0.09 ENSMUST00000114739.1
popeye domain containing 2
chr18_+_60560730 0.08 ENSMUST00000025506.6
RNA binding motif protein 22
chr16_+_23058250 0.07 ENSMUST00000039492.6
ENSMUST00000023589.8
ENSMUST00000089902.6
kininogen 1
chr6_-_144209471 0.07 ENSMUST00000038815.7
SRY-box containing gene 5
chrX_+_74127463 0.07 ENSMUST00000033771.4
ENSMUST00000101457.3
opsin 1 (cone pigments), medium-wave-sensitive (color blindness, deutan)
chr13_+_55369732 0.07 ENSMUST00000063771.7
regulator of G-protein signaling 14
chr3_-_59101810 0.07 ENSMUST00000085040.4
G protein-coupled receptor 171
chr14_+_54426902 0.06 ENSMUST00000010550.7
mitochondrial ribosomal protein L52
chr10_-_51631458 0.06 ENSMUST00000020062.3
G protein-coupled receptor, family C, group 6, member A
chr16_-_23029080 0.06 ENSMUST00000100046.2
kininogen 2
chr16_-_23029012 0.06 ENSMUST00000039338.6
kininogen 2
chr8_-_111854278 0.06 ENSMUST00000034432.5
craniofacial development protein 1
chr16_+_8470763 0.05 ENSMUST00000046470.9
ENSMUST00000150790.1
ENSMUST00000142899.1
methyltransferase like 22
chr8_-_60954726 0.05 ENSMUST00000110302.1
chloride channel 3
chr2_+_80617045 0.05 ENSMUST00000028384.4
dual specificity phosphatase 19
chr8_-_105295934 0.05 ENSMUST00000057855.3
exocyst complex component 3-like
chr7_+_126976338 0.05 ENSMUST00000032920.3
CDP-diacylglycerol--inositol 3-phosphatidyltransferase (phosphatidylinositol synthase)
chr6_-_144209448 0.05 ENSMUST00000077160.5
SRY-box containing gene 5
chr3_-_98763053 0.04 ENSMUST00000107019.1
ENSMUST00000107018.1
ENSMUST00000125483.1
ENSMUST00000137008.1
ENSMUST00000135706.1
hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 3
chr9_-_75597643 0.04 ENSMUST00000164100.1
tropomodulin 2
chr8_-_93337195 0.04 ENSMUST00000044602.7
carboxylesterase 1G
chr15_-_96460838 0.04 ENSMUST00000047835.6
SR-related CTD-associated factor 11
chr2_+_121456963 0.04 ENSMUST00000126764.1
huntingtin interacting protein K
chr5_-_137858034 0.03 ENSMUST00000110978.2
paired immunoglobin-like type 2 receptor beta 1
chr5_-_123721007 0.03 ENSMUST00000031376.7
zinc finger, CCHC domain containing 8
chr11_-_59449913 0.03 ENSMUST00000136436.1
ENSMUST00000150297.1
synaptosomal-associated protein, 47
chr3_-_58885212 0.03 ENSMUST00000055636.6
ENSMUST00000072551.6
ENSMUST00000051408.7
clarin 1
chr6_-_144209558 0.03 ENSMUST00000111749.1
ENSMUST00000170367.2
SRY-box containing gene 5
chr10_+_19621992 0.03 ENSMUST00000036564.7
interleukin 22 receptor, alpha 2
chr17_+_46428917 0.02 ENSMUST00000113465.3
cysteine-rich protein 3
chr7_+_29238323 0.02 ENSMUST00000108238.1
ENSMUST00000032809.3
ENSMUST00000138128.1
Yip1 interacting factor homolog B (S. cerevisiae)
chr8_+_107150621 0.02 ENSMUST00000034400.3
cytochrome b5 type B
chr19_+_34583528 0.02 ENSMUST00000102825.3
interferon-induced protein with tetratricopeptide repeats 3
chr10_-_130394241 0.02 ENSMUST00000094502.4
vomeronasal 2, receptor 84
chr4_+_118961578 0.02 ENSMUST00000058651.4
L-amino acid oxidase 1
chr15_+_85205949 0.02 ENSMUST00000057410.7
ENSMUST00000109432.3
fibulin 1
chr11_-_77894096 0.01 ENSMUST00000017597.4
pipecolic acid oxidase
chr2_+_102659213 0.01 ENSMUST00000111213.1
solute carrier family 1 (glial high affinity glutamate transporter), member 2
chr9_+_21337828 0.01 ENSMUST00000034697.7
solute carrier family 44, member 2
chr19_+_6306456 0.01 ENSMUST00000025681.7
CDC42 binding protein kinase gamma (DMPK-like)
chr18_-_36197343 0.00 ENSMUST00000115713.1
ENSMUST00000115712.1
neuregulin 2
chr3_-_153725062 0.00 ENSMUST00000064460.5
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 3
chr17_-_55712571 0.00 ENSMUST00000086876.5
protection of telomeres 1B

Network of associatons between targets according to the STRING database.

First level regulatory network of Sox17

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:2000547 regulation of dendritic cell dendrite assembly(GO:2000547)
0.2 0.6 GO:2000373 regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000371) positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000373)
0.2 0.5 GO:0031335 regulation of sulfur amino acid metabolic process(GO:0031335)
0.2 0.6 GO:0070859 positive regulation of bile acid biosynthetic process(GO:0070859) positive regulation of bile acid metabolic process(GO:1904253)
0.1 0.3 GO:2000328 regulation of T-helper 17 cell lineage commitment(GO:2000328)
0.1 0.5 GO:0002361 CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361)
0.1 0.3 GO:0033092 positive regulation of immature T cell proliferation in thymus(GO:0033092)
0.0 0.8 GO:0045086 positive regulation of interleukin-2 biosynthetic process(GO:0045086)
0.0 0.2 GO:0009816 defense response, incompatible interaction(GO:0009814) defense response to bacterium, incompatible interaction(GO:0009816) regulation of defense response to bacterium, incompatible interaction(GO:1902477)
0.0 0.2 GO:0060931 sinoatrial node cell development(GO:0060931)
0.0 0.4 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.1 GO:0000480 endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000480)
0.0 0.2 GO:0044791 modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
0.0 0.5 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.0 0.1 GO:0061588 calcium activated phospholipid scrambling(GO:0061588) calcium activated phosphatidylcholine scrambling(GO:0061590) calcium activated galactosylceramide scrambling(GO:0061591)
0.0 0.1 GO:0002528 regulation of vascular permeability involved in acute inflammatory response(GO:0002528) sarcomerogenesis(GO:0048769)
0.0 0.1 GO:0051866 general adaptation syndrome(GO:0051866)
0.0 0.1 GO:0098734 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.0 0.6 GO:0051084 'de novo' posttranslational protein folding(GO:0051084)
0.0 0.1 GO:0097401 synaptic vesicle lumen acidification(GO:0097401)
0.0 0.4 GO:0035634 response to stilbenoid(GO:0035634)
0.0 0.2 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.0 0.3 GO:0042359 vitamin D metabolic process(GO:0042359)
0.0 0.1 GO:0060164 regulation of timing of neuron differentiation(GO:0060164)
0.0 0.0 GO:0046341 CDP-diacylglycerol metabolic process(GO:0046341)
0.0 0.3 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.1 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.1 GO:0098870 neuronal action potential propagation(GO:0019227) action potential propagation(GO:0098870)
0.0 0.1 GO:0045719 negative regulation of glycogen biosynthetic process(GO:0045719)
0.0 0.2 GO:0031017 exocrine pancreas development(GO:0031017)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0000799 nuclear condensin complex(GO:0000799)
0.1 0.5 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.1 0.8 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462) Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.4 GO:0097427 microtubule bundle(GO:0097427)
0.0 0.7 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.4 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.1 GO:0071006 U2-type catalytic step 1 spliceosome(GO:0071006)
0.0 0.2 GO:0005686 U2 snRNP(GO:0005686)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.8 GO:0005171 hepatocyte growth factor receptor binding(GO:0005171)
0.2 0.5 GO:0016206 catechol O-methyltransferase activity(GO:0016206)
0.1 0.6 GO:0004382 guanosine-diphosphatase activity(GO:0004382)
0.1 0.6 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.1 0.3 GO:1902271 D3 vitamins binding(GO:1902271)
0.1 0.5 GO:0004748 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.1 0.3 GO:0004566 beta-glucuronidase activity(GO:0004566)
0.1 0.3 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.2 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.0 0.3 GO:0008494 translation activator activity(GO:0008494)
0.0 0.1 GO:0004687 myosin light chain kinase activity(GO:0004687)
0.0 0.3 GO:0097027 ubiquitin-protein transferase activator activity(GO:0097027)
0.0 0.6 GO:0017127 cholesterol transporter activity(GO:0017127)
0.0 0.1 GO:0004165 dodecenoyl-CoA delta-isomerase activity(GO:0004165)
0.0 0.1 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.0 0.2 GO:0016428 tRNA (cytosine-5-)-methyltransferase activity(GO:0016428)
0.0 0.6 GO:0048020 CCR chemokine receptor binding(GO:0048020)
0.0 0.1 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.0 0.4 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.5 GO:0043395 heparan sulfate proteoglycan binding(GO:0043395)
0.0 0.3 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.1 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.0 0.1 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 PID AURORA B PATHWAY Aurora B signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.0 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 0.5 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.0 0.3 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.5 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 0.3 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling