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2D miR_HR1_12

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Results for Cbfb

Z-value: 0.30

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Transcription factors associated with Cbfb

Gene Symbol Gene ID Gene Info
ENSMUSG00000031885.7 core binding factor beta

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Cbfbmm10_v2_chr8_+_105170668_1051706860.471.2e-01Click!

Activity profile of Cbfb motif

Sorted Z-values of Cbfb motif

Promoter Log-likelihood Transcript Gene Gene Info
chr15_+_62039216 0.45 ENSMUST00000183297.1
plasmacytoma variant translocation 1
chr1_+_40515362 0.39 ENSMUST00000027237.5
interleukin 18 receptor accessory protein
chr6_-_136781718 0.35 ENSMUST00000078095.6
ENSMUST00000032338.7
guanylate cyclase 2c
chr4_+_108847827 0.22 ENSMUST00000102738.2
KTI12 homolog, chromatin associated (S. cerevisiae)
chr17_+_12119274 0.20 ENSMUST00000024594.2
1-acylglycerol-3-phosphate O-acyltransferase 4 (lysophosphatidic acid acyltransferase, delta)
chr6_-_99726392 0.19 ENSMUST00000032152.8
ENSMUST00000101120.4
ENSMUST00000008273.6
prokineticin 2
chr8_+_27260327 0.19 ENSMUST00000033880.5
eukaryotic translation initiation factor 4E binding protein 1
chrX_-_101734125 0.19 ENSMUST00000056614.6
chemokine (C-X-C motif) receptor 3
chr2_+_172393794 0.17 ENSMUST00000099061.2
ENSMUST00000103073.2
Cas scaffolding protein family member 4
chr11_-_83649349 0.17 ENSMUST00000001008.5
chemokine (C-C motif) ligand 3
chr2_+_35132194 0.16 ENSMUST00000113034.1
ENSMUST00000113037.3
ENSMUST00000113033.2
centrosomal protein 110
chr17_-_35643684 0.15 ENSMUST00000095467.3
diffuse panbronchiolitis critical region 1 (human)
chr2_+_72297895 0.14 ENSMUST00000144111.1
sterile alpha motif and leucine zipper containing kinase AZK
chr11_-_17008647 0.13 ENSMUST00000102881.3
pleckstrin
chr19_+_12798574 0.12 ENSMUST00000025601.6
leupaxin
chr14_+_101729907 0.11 ENSMUST00000100337.3
LIM domain only 7
chr2_-_58160495 0.11 ENSMUST00000028175.6
cytohesin 1 interacting protein
chr1_+_63176818 0.11 ENSMUST00000129339.1
eukaryotic translation elongation factor 1 beta 2
chr11_-_54249640 0.11 ENSMUST00000019060.5
colony stimulating factor 2 (granulocyte-macrophage)
chr11_+_20631956 0.08 ENSMUST00000109586.2
SERTA domain containing 2
chr15_-_9529868 0.08 ENSMUST00000003981.4
interleukin 7 receptor
chr1_-_193264006 0.08 ENSMUST00000161737.1
hydroxysteroid 11-beta dehydrogenase 1
chr2_+_172393900 0.07 ENSMUST00000109136.2
Cas scaffolding protein family member 4
chrX_+_21714896 0.06 ENSMUST00000033414.7
solute carrier family 6 (neurotransmitter transporter), member 14
chr15_-_66801577 0.06 ENSMUST00000168589.1
src-like adaptor
chr3_-_146651304 0.06 ENSMUST00000149825.1
ENSMUST00000049703.5
RIKEN cDNA 4930503B20 gene
chr8_+_84125989 0.06 ENSMUST00000093380.4
podocan-like 1
chr1_-_63176653 0.06 ENSMUST00000027111.8
ENSMUST00000168099.2
NADH dehydrogenase (ubiquinone) Fe-S protein 1
chr5_-_147400352 0.05 ENSMUST00000049324.8
ENSMUST00000176456.1
ENSMUST00000110549.1
FMS-like tyrosine kinase 3
chr11_-_74724670 0.05 ENSMUST00000021091.8
platelet-activating factor acetylhydrolase, isoform 1b, subunit 1
chr16_-_92826004 0.05 ENSMUST00000023673.7
runt related transcription factor 1
chr6_+_126853091 0.05 ENSMUST00000095440.5
A kinase (PRKA) anchor protein 3
chr6_+_129408854 0.05 ENSMUST00000058352.8
ENSMUST00000164513.2
ENSMUST00000088075.5
C-type lectin domain family 9, member a
chr1_-_16656843 0.05 ENSMUST00000115352.3
transcription elongation factor B (SIII), polypeptide 1
chr7_-_115824699 0.04 ENSMUST00000169129.1
SRY-box containing gene 6
chr19_+_5050807 0.04 ENSMUST00000025818.6
Ras and Rab interactor 1
chr9_+_110849507 0.04 ENSMUST00000119427.2
protease, serine, 46
chr2_+_153938218 0.03 ENSMUST00000109757.1
BPI fold containing family B, member 4
chr11_-_73326472 0.03 ENSMUST00000155630.2
aspartoacylase
chr16_-_38433145 0.02 ENSMUST00000002926.6
phospholipase A1 member A
chr3_+_121291725 0.01 ENSMUST00000039442.7
asparagine-linked glycosylation 14
chr19_-_50678485 0.01 ENSMUST00000111756.3
VPS10 domain receptor protein SORCS 1
chr7_-_46795881 0.01 ENSMUST00000107653.1
ENSMUST00000107654.1
ENSMUST00000014562.7
ENSMUST00000152759.1
Hermansky-Pudlak syndrome 5 homolog (human)
chr14_+_64950037 0.01 ENSMUST00000043914.5
integrator complex subunit 9
chr11_-_73326807 0.01 ENSMUST00000134079.1
aspartoacylase
chr15_-_101869695 0.00 ENSMUST00000087996.5
keratin 77
chr4_-_117891994 0.00 ENSMUST00000030265.3
DPH2 homolog (S. cerevisiae)

Network of associatons between targets according to the STRING database.

First level regulatory network of Cbfb

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0060983 epicardium-derived cardiac vascular smooth muscle cell differentiation(GO:0060983)
0.0 0.2 GO:1990928 response to amino acid starvation(GO:1990928)
0.0 0.1 GO:0006713 glucocorticoid catabolic process(GO:0006713)
0.0 0.1 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.0 0.1 GO:0070560 negative regulation of inositol phosphate biosynthetic process(GO:0010920) protein secretion by platelet(GO:0070560)
0.0 0.1 GO:0002572 pro-T cell differentiation(GO:0002572)
0.0 0.1 GO:2000872 positive regulation of progesterone secretion(GO:2000872)
0.0 0.1 GO:0050859 negative regulation of B cell receptor signaling pathway(GO:0050859)
0.0 0.2 GO:1900118 negative regulation of execution phase of apoptosis(GO:1900118)
0.0 0.2 GO:0043615 astrocyte cell migration(GO:0043615)
0.0 0.1 GO:0051661 maintenance of centrosome location(GO:0051661)
0.0 0.1 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.0 0.3 GO:0008074 guanylate cyclase complex, soluble(GO:0008074)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0004908 interleukin-1 receptor activity(GO:0004908)
0.0 0.2 GO:0019958 C-X-C chemokine binding(GO:0019958)
0.0 0.1 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.0 0.1 GO:0005275 amine transmembrane transporter activity(GO:0005275)
0.0 0.3 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.2 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.0 GO:0019807 aspartoacylase activity(GO:0019807)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME MTORC1 MEDIATED SIGNALLING Genes involved in mTORC1-mediated signalling