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2D miR_HR1_12

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Results for Hey1_Myc_Mxi1

Z-value: 3.02

Motif logo

Transcription factors associated with Hey1_Myc_Mxi1

Gene Symbol Gene ID Gene Info
ENSMUSG00000040289.3 hairy/enhancer-of-split related with YRPW motif 1
ENSMUSG00000022346.8 myelocytomatosis oncogene
ENSMUSG00000025025.7 MAX interactor 1, dimerization protein

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Mxi1mm10_v2_chr19_+_53329413_533294780.931.2e-05Click!
Mycmm10_v2_chr15_+_61985377_619853970.737.0e-03Click!
Hey1mm10_v2_chr3_-_8667033_8667046-0.594.4e-02Click!

Activity profile of Hey1_Myc_Mxi1 motif

Sorted Z-values of Hey1_Myc_Mxi1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr3_+_104638658 13.38 ENSMUST00000046212.1
solute carrier family 16 (monocarboxylic acid transporters), member 1
chr2_+_164769892 10.32 ENSMUST00000088248.6
ENSMUST00000001439.6
ubiquitin-conjugating enzyme E2C
chr9_+_107587711 10.27 ENSMUST00000010192.5
interferon-related developmental regulator 2
chr4_+_134468320 10.18 ENSMUST00000030636.4
ENSMUST00000127279.1
ENSMUST00000105867.1
stathmin 1
chr7_+_141476374 9.25 ENSMUST00000117634.1
tetraspanin 4
chr16_-_57606816 8.76 ENSMUST00000114371.3
cms small ribosomal subunit 1
chr12_+_109459843 7.68 ENSMUST00000173812.1
delta-like 1 homolog (Drosophila)
chr2_+_127336152 7.06 ENSMUST00000028846.6
dual specificity phosphatase 2
chr9_-_22389113 6.47 ENSMUST00000040912.7
anillin, actin binding protein
chr2_+_130274424 6.40 ENSMUST00000103198.4
NOP56 ribonucleoprotein
chr18_+_35553401 6.37 ENSMUST00000181664.1
small nucleolar RNA host gene 4 (non-protein coding)
chr7_-_4445181 6.34 ENSMUST00000138798.1
retinol dehydrogenase 13 (all-trans and 9-cis)
chr17_-_24658425 6.24 ENSMUST00000095544.4
neuropeptide W
chr13_-_55329723 6.20 ENSMUST00000021941.7
Max dimerization protein 3
chr4_-_130574150 6.09 ENSMUST00000105993.3
Na+/K+ transporting ATPase interacting 1
chr2_+_30286406 6.05 ENSMUST00000138666.1
ENSMUST00000113634.2
nucleoporin 188
chrX_-_134541847 5.98 ENSMUST00000054213.4
translocase of inner mitochondrial membrane 8A1
chr12_-_36156781 5.73 ENSMUST00000020856.4
basic leucine zipper and W2 domains 2
chr2_+_130274437 5.61 ENSMUST00000141872.1
NOP56 ribonucleoprotein
chr4_+_11191354 5.57 ENSMUST00000170901.1
cyclin E2
chr10_+_103367748 5.43 ENSMUST00000074204.4
ENSMUST00000179636.1
solute carrier family 6 (neurotransmitter transporter), member 15
chr17_-_35000848 5.32 ENSMUST00000166828.3
DNA segment, Chr 17, human D6S56E 5
chr4_-_132757162 5.28 ENSMUST00000030709.8
sphingomyelin phosphodiesterase, acid-like 3B
chr15_-_53902472 5.24 ENSMUST00000078673.6
sterile alpha motif domain containing 12
chr17_+_56040350 5.05 ENSMUST00000002914.8
chromatin assembly factor 1, subunit A (p150)
chr17_-_35000746 5.02 ENSMUST00000163360.1
DNA segment, Chr 17, human D6S56E 5
chr5_-_135251209 5.02 ENSMUST00000062572.2
frizzled homolog 9 (Drosophila)
chr11_+_103649498 5.00 ENSMUST00000057870.2
reprimo-like
chr1_+_172482199 4.97 ENSMUST00000135267.1
ENSMUST00000052629.6
ENSMUST00000111235.2
immunoglobulin superfamily, member 9
chr10_+_127063599 4.89 ENSMUST00000120226.1
ENSMUST00000133115.1
cyclin-dependent kinase 4
chr8_-_13254154 4.87 ENSMUST00000033825.4
ADP-ribosylhydrolase like 1
chr1_-_55088156 4.86 ENSMUST00000127861.1
ENSMUST00000144077.1
heat shock protein 1 (chaperonin)
chrX_-_93632113 4.82 ENSMUST00000006856.2
polymerase (DNA directed), alpha 1
chr4_-_139352538 4.82 ENSMUST00000102503.3
MRT4, mRNA turnover 4, homolog (S. cerevisiae)
chr17_+_46496753 4.81 ENSMUST00000046497.6
2'-deoxynucleoside 5'-phosphate N-hydrolase 1
chr1_-_75180349 4.80 ENSMUST00000027396.8
ATP-binding cassette, sub-family B (MDR/TAP), member 6
chr4_-_139352298 4.75 ENSMUST00000030513.6
ENSMUST00000155257.1
MRT4, mRNA turnover 4, homolog (S. cerevisiae)
chr1_-_12991109 4.70 ENSMUST00000115403.2
ENSMUST00000115402.1
solute carrier organic anion transporter family, member 5A1
chr18_+_14783238 4.70 ENSMUST00000169862.1
TAF4B RNA polymerase II, TATA box binding protein (TBP)-associated factor
chr11_+_78178651 4.69 ENSMUST00000092880.7
ENSMUST00000127587.1
ENSMUST00000108338.1
TLC domain containing 1
chr2_+_30286383 4.68 ENSMUST00000064447.5
nucleoporin 188
chr14_-_31019055 4.63 ENSMUST00000037739.6
guanine nucleotide binding protein-like 3 (nucleolar)
chr9_+_44066993 4.60 ENSMUST00000034508.7
ubiquitin specific peptidase 2
chr7_-_45466894 4.53 ENSMUST00000033093.8
BCL2-associated X protein
chr4_+_148591482 4.47 ENSMUST00000006611.8
spermidine synthase
chr2_-_11502090 4.41 ENSMUST00000179584.1
ENSMUST00000170196.2
ENSMUST00000171188.2
ENSMUST00000114845.3
ENSMUST00000114844.1
ENSMUST00000100411.2
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
chr15_-_98881255 4.40 ENSMUST00000024518.9
Ras homolog enriched in brain like 1
chrX_-_73921917 4.39 ENSMUST00000114389.3
N(alpha)-acetyltransferase 10, NatA catalytic subunit
chr3_-_129831374 4.38 ENSMUST00000029643.8
GAR1 ribonucleoprotein homolog (yeast)
chr3_+_88532314 4.31 ENSMUST00000172699.1
mex3 homolog A (C. elegans)
chr10_-_81001338 4.29 ENSMUST00000099462.1
ENSMUST00000118233.1
guanine nucleotide binding protein (G protein), gamma 7
chrX_-_73921828 4.27 ENSMUST00000096316.3
ENSMUST00000114390.1
ENSMUST00000114391.3
ENSMUST00000114387.1
N(alpha)-acetyltransferase 10, NatA catalytic subunit
chrX_-_73921930 4.27 ENSMUST00000033763.8
N(alpha)-acetyltransferase 10, NatA catalytic subunit
chr11_-_76217490 4.23 ENSMUST00000102500.4
gem (nuclear organelle) associated protein 4
chr8_-_70234097 4.22 ENSMUST00000130319.1
armadillo repeat containing 6
chr17_+_45563928 4.21 ENSMUST00000041353.6
solute carrier family 35, member B2
chrX_+_73639414 4.11 ENSMUST00000019701.8
dual specificity phosphatase 9
chr16_-_78576649 4.05 ENSMUST00000114220.1
ENSMUST00000114219.1
ENSMUST00000114218.1
DNA segment, Chr 16, ERATO Doi 472, expressed
chr14_-_89898466 4.01 ENSMUST00000081204.4
predicted gene 10110
chr4_+_101419696 3.99 ENSMUST00000131397.1
ENSMUST00000133055.1
adenylate kinase 4
chr11_-_97629685 3.94 ENSMUST00000052281.4
RIKEN cDNA E130012A19 gene
chrX_+_153139941 3.92 ENSMUST00000039720.4
ENSMUST00000144175.2
Ras-related GTP binding B
chrX_-_48208566 3.91 ENSMUST00000037960.4
zinc finger, DHHC domain containing 9
chr12_-_71136611 3.86 ENSMUST00000021486.8
ENSMUST00000166120.1
translocase of inner mitochondrial membrane 9
chr6_+_120666388 3.85 ENSMUST00000112686.1
cat eye syndrome chromosome region, candidate 2
chr1_+_59684949 3.83 ENSMUST00000027174.3
NOP58 ribonucleoprotein
chr17_+_71616215 3.82 ENSMUST00000047086.9
WD repeat domain 43
chr15_-_77956658 3.81 ENSMUST00000117725.1
ENSMUST00000016696.6
FAD-dependent oxidoreductase domain containing 2
chr1_-_75219245 3.80 ENSMUST00000079464.6
tubulin, alpha 4A
chr1_-_55088024 3.78 ENSMUST00000027123.8
heat shock protein 1 (chaperonin)
chr3_+_145576196 3.78 ENSMUST00000098534.4
zinc finger, HIT type 6
chr3_-_95882031 3.78 ENSMUST00000161994.1
predicted gene 129
chr7_-_4445595 3.77 ENSMUST00000119485.1
retinol dehydrogenase 13 (all-trans and 9-cis)
chr17_-_56935388 3.72 ENSMUST00000025053.8
myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 1
chr9_+_106477269 3.66 ENSMUST00000047721.8
RRP9, small subunit (SSU) processome component, homolog (yeast)
chr11_+_84179792 3.64 ENSMUST00000137500.2
ENSMUST00000130012.2
acetyl-Coenzyme A carboxylase alpha
chr6_-_131388417 3.63 ENSMUST00000032309.6
ENSMUST00000087865.2
Y box protein 3
chr7_-_48881032 3.62 ENSMUST00000058745.8
E2F transcription factor 8
chr4_-_89282152 3.62 ENSMUST00000060501.4
cyclin-dependent kinase inhibitor 2A
chr11_-_77489666 3.62 ENSMUST00000037593.7
ENSMUST00000092892.3
ankyrin repeat domain 13b
chr17_-_26201363 3.61 ENSMUST00000121959.1
Rho GDP dissociation inhibitor (GDI) gamma
chr6_-_148946146 3.58 ENSMUST00000132696.1
family with sequence similarity 60, member A
chr13_-_38658991 3.53 ENSMUST00000001757.7
eukaryotic translation elongation factor 1 epsilon 1
chr7_+_28169744 3.52 ENSMUST00000042405.6
fibrillarin
chr14_-_68124836 3.51 ENSMUST00000111089.1
ENSMUST00000022638.5
neurofilament, medium polypeptide
chr18_+_32837225 3.46 ENSMUST00000166214.1
ENSMUST00000053663.9
WD repeat domain 36
chr2_-_11502067 3.41 ENSMUST00000028114.6
ENSMUST00000049849.6
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
chr4_+_101419277 3.38 ENSMUST00000102780.1
ENSMUST00000106946.1
ENSMUST00000106945.1
adenylate kinase 4
chr7_-_99182681 3.35 ENSMUST00000033001.4
diacylglycerol O-acyltransferase 2
chr1_+_172481788 3.35 ENSMUST00000127052.1
immunoglobulin superfamily, member 9
chr17_-_31512253 3.32 ENSMUST00000166626.1
WD repeat domain 4
chr3_+_159495408 3.25 ENSMUST00000120272.1
ENSMUST00000029825.7
ENSMUST00000106041.2
DEP domain containing 1a
chr6_+_125131869 3.24 ENSMUST00000044200.8
NOP2 nucleolar protein
chr19_-_10203880 3.22 ENSMUST00000142241.1
ENSMUST00000116542.2
ENSMUST00000025651.5
ENSMUST00000156291.1
flap structure specific endonuclease 1
chr19_+_6975048 3.22 ENSMUST00000070850.6
protein phosphatase 1, regulatory (inhibitor) subunit 14B
chr10_-_127522428 3.18 ENSMUST00000026470.4
serine hydroxymethyltransferase 2 (mitochondrial)
chr2_+_71873224 3.18 ENSMUST00000006669.5
pyruvate dehydrogenase kinase, isoenzyme 1
chr11_-_93885752 3.12 ENSMUST00000066888.3
UTP18, small subunit (SSU) processome component, homolog (yeast)
chr4_+_152325831 3.11 ENSMUST00000103191.4
ENSMUST00000139685.1
ribosomal protein L22
chr11_-_60811228 3.08 ENSMUST00000018744.8
serine hydroxymethyltransferase 1 (soluble)
chr18_+_67464849 3.08 ENSMUST00000025411.7
slowmo homolog 1 (Drosophila)
chr11_+_101316200 3.05 ENSMUST00000142640.1
ENSMUST00000019470.7
proteaseome (prosome, macropain) activator subunit 3 (PA28 gamma, Ki)
chr1_-_162548484 3.03 ENSMUST00000028017.9
methyltransferase like 13
chr9_+_44067072 3.02 ENSMUST00000177054.1
ubiquitin specific peptidase 2
chr15_+_62037986 3.02 ENSMUST00000182956.1
ENSMUST00000182075.1
ENSMUST00000180432.2
ENSMUST00000181416.2
ENSMUST00000181657.2
plasmacytoma variant translocation 1
chr3_-_90052463 3.02 ENSMUST00000029553.9
ENSMUST00000064639.8
ENSMUST00000090908.6
ubiquitin associated protein 2-like
chr7_-_4445637 3.01 ENSMUST00000008579.7
retinol dehydrogenase 13 (all-trans and 9-cis)
chr14_+_50924968 3.01 ENSMUST00000049411.5
ENSMUST00000136753.1
ENSMUST00000154288.1
apurinic/apyrimidinic endonuclease 1
chr4_-_116821501 2.97 ENSMUST00000055436.3
4-hydroxyphenylpyruvate dioxygenase-like
chr1_+_71557149 2.97 ENSMUST00000027384.5
5-aminoimidazole-4-carboxamide ribonucleotide formyltransferase/IMP cyclohydrolase
chr7_+_78895903 2.95 ENSMUST00000107425.1
ENSMUST00000107421.1
ENSMUST00000107423.1
apoptosis enhancing nuclease
chr1_+_178187721 2.94 ENSMUST00000159284.1
desumoylating isopeptidase 2
chr7_-_63212514 2.93 ENSMUST00000032738.5
cholinergic receptor, nicotinic, alpha polypeptide 7
chr14_+_3412614 2.91 ENSMUST00000170123.1
predicted gene 10409
chr4_-_149774238 2.91 ENSMUST00000105686.2
solute carrier family 25, member 33
chr2_+_155611175 2.89 ENSMUST00000092995.5
myosin, heavy chain 7B, cardiac muscle, beta
chr7_+_19577287 2.88 ENSMUST00000108453.1
zinc finger protein 296
chr3_-_37724321 2.84 ENSMUST00000108105.1
ENSMUST00000079755.4
ENSMUST00000099128.1
predicted gene 5148
chr7_-_45128725 2.80 ENSMUST00000150350.1
ribosomal protein L13A
chr7_+_16875302 2.78 ENSMUST00000108493.1
dapper homolog 3, antagonist of beta-catenin (xenopus)
chr2_-_102451792 2.75 ENSMUST00000099678.3
four jointed box 1 (Drosophila)
chr16_+_35770382 2.75 ENSMUST00000023555.4
Hspb associated protein 1
chr11_-_84513485 2.73 ENSMUST00000018841.2
apoptosis antagonizing transcription factor
chr11_-_78165521 2.72 ENSMUST00000017530.3
TNF receptor associated factor 4
chr13_-_81710937 2.70 ENSMUST00000161920.1
ENSMUST00000048993.5
polymerase (RNA) III (DNA directed) polypeptide G
chr1_-_179546261 2.66 ENSMUST00000027769.5
transcription factor B2, mitochondrial
chr11_+_76217608 2.64 ENSMUST00000040806.4
diazepam binding inhibitor-like 5
chr17_-_33781535 2.64 ENSMUST00000002360.9
angiopoietin-like 4
chr11_+_51619731 2.63 ENSMUST00000127405.1
NHP2 ribonucleoprotein
chr2_+_132816141 2.62 ENSMUST00000028831.8
ENSMUST00000066559.5
minichromosome maintenance deficient 8 (S. cerevisiae)
chr17_+_35001282 2.61 ENSMUST00000174260.1
valyl-tRNA synthetase
chr5_-_77310049 2.58 ENSMUST00000047860.8
nitric oxide associated 1
chr2_-_128943985 2.58 ENSMUST00000028866.8
zinc finger CCCH type containing 8
chr1_-_17097839 2.57 ENSMUST00000038382.4
junctophilin 1
chr11_-_97782377 2.55 ENSMUST00000128801.1
ribosomal protein L23
chr1_+_171345684 2.54 ENSMUST00000006579.4
prefoldin 2
chr2_+_22895583 2.54 ENSMUST00000152170.1
prenyl (solanesyl) diphosphate synthase, subunit 1
chr2_-_119618455 2.52 ENSMUST00000123818.1
Opa interacting protein 5
chr1_+_63176818 2.51 ENSMUST00000129339.1
eukaryotic translation elongation factor 1 beta 2
chr11_+_101316917 2.51 ENSMUST00000151385.1
proteaseome (prosome, macropain) activator subunit 3 (PA28 gamma, Ki)
chr15_-_78773452 2.51 ENSMUST00000018313.5
MFNG O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase
chr2_+_22895482 2.51 ENSMUST00000053729.7
prenyl (solanesyl) diphosphate synthase, subunit 1
chr10_+_79974409 2.51 ENSMUST00000131816.1
glutamate receptor, ionotropic, NMDA3B
chr19_-_41896132 2.50 ENSMUST00000038677.3
ribosomal RNA processing 12 homolog (S. cerevisiae)
chr6_-_145076106 2.50 ENSMUST00000111742.1
ENSMUST00000048252.4
branched chain aminotransferase 1, cytosolic
chr2_+_119618717 2.49 ENSMUST00000028771.7
nucleolar and spindle associated protein 1
chr14_+_120911177 2.49 ENSMUST00000032898.7
importin 5
chr12_-_72917760 2.46 ENSMUST00000110489.2
RIKEN cDNA 4930447C04 gene
chr2_-_181135103 2.45 ENSMUST00000149964.2
ENSMUST00000103050.3
ENSMUST00000081528.6
ENSMUST00000049792.8
ENSMUST00000103048.3
ENSMUST00000103047.3
ENSMUST00000129073.1
ENSMUST00000144592.1
ENSMUST00000139458.1
ENSMUST00000154164.1
ENSMUST00000123336.1
ENSMUST00000129361.1
ENSMUST00000103051.2
potassium voltage-gated channel, subfamily Q, member 2
chr17_-_84790517 2.45 ENSMUST00000112308.2
leucine-rich PPR-motif containing
chr2_-_33130565 2.43 ENSMUST00000124000.1
GTPase activating RANGAP domain-like 3
chr9_+_95637601 2.42 ENSMUST00000015498.8
procollagen C-endopeptidase enhancer 2
chr19_-_4201591 2.41 ENSMUST00000025740.6
RAD9 homolog A
chr8_+_84990585 2.40 ENSMUST00000064495.6
hook homolog 2 (Drosophila)
chr6_+_128362919 2.40 ENSMUST00000073316.6
forkhead box M1
chr8_-_70234401 2.40 ENSMUST00000019679.5
armadillo repeat containing 6
chr5_-_136244865 2.40 ENSMUST00000005188.9
SH2B adaptor protein 2
chr8_+_125734203 2.39 ENSMUST00000034313.6
ENSMUST00000065135.5
nucleoside-triphosphatase, cancer-related
chr13_+_108316332 2.38 ENSMUST00000051594.5
DEP domain containing 1B
chr7_+_24884809 2.36 ENSMUST00000156372.1
ENSMUST00000124035.1
ribosomal protein S19
chr7_-_45830776 2.36 ENSMUST00000107723.2
ENSMUST00000131384.1
glutamate-rich WD repeat containing 1
chr11_-_97782409 2.34 ENSMUST00000103146.4
ribosomal protein L23
chr14_+_115042752 2.34 ENSMUST00000134140.2
Mir17 host gene 1 (non-protein coding)
chr14_+_45351473 2.33 ENSMUST00000111835.2
serine/threonine/tyrosine interaction protein
chr1_+_9545397 2.32 ENSMUST00000072079.7
RRS1 ribosome biogenesis regulator homolog (S. cerevisiae)
chr14_-_21848924 2.28 ENSMUST00000124549.1
catechol-O-methyltransferase domain containing 1
chr5_+_45493374 2.28 ENSMUST00000046122.6
leucine aminopeptidase 3
chr7_+_16310412 2.28 ENSMUST00000136781.1
BCL2 binding component 3
chr17_-_26201328 2.28 ENSMUST00000025019.2
Rho GDP dissociation inhibitor (GDI) gamma
chr9_-_78481724 2.27 ENSMUST00000042235.8
eukaryotic translation elongation factor 1 alpha 1
chr9_+_65587187 2.27 ENSMUST00000047099.5
ENSMUST00000131483.1
ENSMUST00000141046.1
PIF1 5'-to-3' DNA helicase homolog (S. cerevisiae)
chr11_+_84880308 2.27 ENSMUST00000020837.6
myosin XIX
chr8_-_106136890 2.26 ENSMUST00000115979.2
epithelial splicing regulatory protein 2
chr1_+_135818593 2.24 ENSMUST00000038760.8
ladinin
chr11_+_72441341 2.23 ENSMUST00000045633.5
MYB binding protein (P160) 1a
chr15_+_102073773 2.22 ENSMUST00000169681.1
eukaryotic translation initiation factor 4B
chr15_+_102296256 2.22 ENSMUST00000064924.4
extra spindle poles-like 1 (S. cerevisiae)
chrX_-_101085352 2.21 ENSMUST00000101362.1
ENSMUST00000073927.4
solute carrier family 7 (cationic amino acid transporter, y+ system), member 3
chrX_-_162829379 2.21 ENSMUST00000041370.4
ENSMUST00000112316.2
ENSMUST00000112315.1
taxilin gamma
chr15_+_44787746 2.21 ENSMUST00000181839.1
RIKEN cDNA 2310069G16 gene
chr8_+_106893616 2.21 ENSMUST00000047629.5
cirrhosis, autosomal recessive 1A (human)
chr9_-_86464900 2.20 ENSMUST00000121189.1
ubiquitin-conjugating enzyme E2C binding protein
chr5_+_38220470 2.19 ENSMUST00000087514.2
ENSMUST00000130721.1
ENSMUST00000123207.1
ENSMUST00000132190.1
ENSMUST00000152066.1
ENSMUST00000155300.1
Ly1 antibody reactive clone
chr2_-_11502025 2.19 ENSMUST00000114846.2
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
chr19_-_16780822 2.17 ENSMUST00000068156.6
vacuolar protein sorting 13A (yeast)
chr11_-_70410010 2.16 ENSMUST00000019065.3
ENSMUST00000135148.1
proline, glutamic acid and leucine rich protein 1
chr5_-_139460501 2.16 ENSMUST00000066052.7
RIKEN cDNA 3110082I17 gene
chr15_+_99029866 2.15 ENSMUST00000058914.8
tubulin, alpha 1C
chr11_+_3963970 2.15 ENSMUST00000020705.4
ENSMUST00000109985.1
pescadillo homolog 1, containing BRCT domain (zebrafish)
chr11_-_12026732 2.14 ENSMUST00000143915.1
growth factor receptor bound protein 10
chr16_+_20672716 2.13 ENSMUST00000044783.7
ENSMUST00000115463.1
ENSMUST00000142344.1
ENSMUST00000073840.5
ENSMUST00000140576.1
ENSMUST00000115457.1
eukaryotic translation initiation factor 4, gamma 1
chr9_-_35116804 2.12 ENSMUST00000034537.6
ST3 beta-galactoside alpha-2,3-sialyltransferase 4
chr9_-_86464944 2.12 ENSMUST00000034986.7
ubiquitin-conjugating enzyme E2C binding protein
chr15_+_34495302 2.12 ENSMUST00000052290.7
ENSMUST00000079028.5
processing of precursor 1, ribonuclease P/MRP family, (S. cerevisiae)
chr5_+_76951382 2.10 ENSMUST00000141687.1
phosphoribosylaminoimidazole carboxylase, phosphoribosylaminoribosylaminoimidazole, succinocarboxamide synthetase
chr9_-_15357692 2.10 ENSMUST00000098979.3
ENSMUST00000161132.1
RIKEN cDNA 5830418K08 gene
chr11_-_69672307 2.10 ENSMUST00000163666.2
eukaryotic translation initiation factor 4A1
chr10_-_78464853 2.09 ENSMUST00000105385.1
pyridoxal (pyridoxine, vitamin B6) kinase
chr2_+_84826997 2.07 ENSMUST00000028470.3
translocase of inner mitochondrial membrane 10
chr2_-_84670659 2.05 ENSMUST00000102646.1
ENSMUST00000102647.3
RIKEN cDNA 2700094K13 gene

Network of associatons between targets according to the STRING database.

First level regulatory network of Hey1_Myc_Mxi1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
3.4 17.2 GO:0090521 glomerular visceral epithelial cell migration(GO:0090521)
2.9 8.6 GO:0002842 positive regulation of T cell mediated immune response to tumor cell(GO:0002842)
2.6 12.9 GO:0030920 N-terminal peptidyl-serine acetylation(GO:0017198) N-terminal peptidyl-glutamic acid acetylation(GO:0018002) peptidyl-serine acetylation(GO:0030920)
1.9 11.1 GO:0048254 snoRNA localization(GO:0048254)
1.7 10.3 GO:0031536 positive regulation of exit from mitosis(GO:0031536)
1.7 5.0 GO:1990523 bone regeneration(GO:1990523)
1.6 1.6 GO:0002188 translation reinitiation(GO:0002188)
1.5 4.5 GO:1902445 B cell negative selection(GO:0002352) regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445)
1.5 13.1 GO:0009644 response to high light intensity(GO:0009644)
1.4 7.1 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
1.4 5.7 GO:0060265 positive regulation of respiratory burst involved in inflammatory response(GO:0060265)
1.4 1.4 GO:0046166 glyceraldehyde-3-phosphate biosynthetic process(GO:0046166)
1.3 13.4 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
1.3 3.9 GO:0010705 meiotic DNA double-strand break processing involved in reciprocal meiotic recombination(GO:0010705)
1.3 8.9 GO:0070494 regulation of thrombin receptor signaling pathway(GO:0070494) negative regulation of thrombin receptor signaling pathway(GO:0070495)
1.2 3.6 GO:0032877 positive regulation of DNA endoreduplication(GO:0032877)
1.2 4.8 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269) leading strand elongation(GO:0006272)
1.2 4.8 GO:0015886 heme transport(GO:0015886)
1.2 4.8 GO:0044268 multicellular organismal protein metabolic process(GO:0044268)
1.2 3.5 GO:0006592 ornithine biosynthetic process(GO:0006592)
1.2 3.5 GO:0033693 neurofilament bundle assembly(GO:0033693)
1.2 5.8 GO:0072717 cellular response to actinomycin D(GO:0072717)
1.2 5.8 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
1.1 4.6 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
1.1 10.0 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
1.1 6.5 GO:0010288 response to lead ion(GO:0010288)
1.1 5.4 GO:0015820 branched-chain amino acid transport(GO:0015803) leucine transport(GO:0015820)
1.1 2.1 GO:0009446 putrescine biosynthetic process(GO:0009446)
1.0 6.3 GO:0006545 glycine biosynthetic process(GO:0006545)
1.0 4.1 GO:0008295 spermidine biosynthetic process(GO:0008295)
1.0 3.0 GO:0002270 plasmacytoid dendritic cell activation(GO:0002270) positive regulation of glycogen catabolic process(GO:0045819)
1.0 7.0 GO:2000774 positive regulation of cellular senescence(GO:2000774)
1.0 4.0 GO:1902219 negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902219)
0.9 3.7 GO:0071051 polyadenylation-dependent snoRNA 3'-end processing(GO:0071051)
0.9 3.7 GO:0000960 mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
0.9 3.5 GO:0050812 regulation of acetyl-CoA biosynthetic process from pyruvate(GO:0010510) regulation of acyl-CoA biosynthetic process(GO:0050812)
0.9 4.4 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.9 2.6 GO:0031120 snRNA pseudouridine synthesis(GO:0031120)
0.9 6.0 GO:0051725 protein de-ADP-ribosylation(GO:0051725)
0.8 6.5 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.8 3.2 GO:0045903 positive regulation of translational fidelity(GO:0045903)
0.8 2.3 GO:0045204 MAPK export from nucleus(GO:0045204)
0.8 4.6 GO:0006685 sphingomyelin catabolic process(GO:0006685)
0.8 3.8 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.7 3.0 GO:0036265 RNA (guanine-N7)-methylation(GO:0036265)
0.7 1.5 GO:0010046 response to mycotoxin(GO:0010046)
0.7 2.9 GO:0001978 regulation of systemic arterial blood pressure by carotid sinus baroreceptor feedback(GO:0001978)
0.7 2.1 GO:1904049 negative regulation of spontaneous neurotransmitter secretion(GO:1904049)
0.7 8.4 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.7 4.1 GO:0044806 G-quadruplex DNA unwinding(GO:0044806)
0.7 2.0 GO:0031660 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662)
0.7 3.3 GO:0070934 CRD-mediated mRNA stabilization(GO:0070934)
0.7 16.5 GO:0000154 rRNA modification(GO:0000154)
0.6 3.8 GO:0090070 positive regulation of ribosome biogenesis(GO:0090070) positive regulation of rRNA processing(GO:2000234)
0.6 2.5 GO:0016340 calcium-dependent cell-matrix adhesion(GO:0016340)
0.6 3.1 GO:0035984 response to trichostatin A(GO:0035983) cellular response to trichostatin A(GO:0035984)
0.6 1.9 GO:1903660 transforming growth factor beta activation(GO:0036363) regulation of complement-dependent cytotoxicity(GO:1903659) negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.6 1.8 GO:1901355 response to rapamycin(GO:1901355)
0.6 1.2 GO:0006244 pyrimidine nucleotide catabolic process(GO:0006244) pyrimidine deoxyribonucleotide catabolic process(GO:0009223)
0.6 2.4 GO:0019919 peptidyl-arginine methylation, to asymmetrical-dimethyl arginine(GO:0019919)
0.6 4.8 GO:0009162 deoxyribonucleoside monophosphate metabolic process(GO:0009162)
0.6 1.8 GO:0019405 hexitol metabolic process(GO:0006059) alditol catabolic process(GO:0019405)
0.6 2.4 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.6 8.9 GO:1904816 positive regulation of protein localization to chromosome, telomeric region(GO:1904816)
0.6 4.1 GO:0045876 positive regulation of sister chromatid cohesion(GO:0045876)
0.6 2.3 GO:0003349 epicardium-derived cardiac endothelial cell differentiation(GO:0003349)
0.6 2.3 GO:1900740 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.6 1.7 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.6 0.6 GO:0000738 DNA catabolic process, exonucleolytic(GO:0000738)
0.5 4.4 GO:1902570 protein localization to nucleolus(GO:1902570)
0.5 3.8 GO:0035356 cellular triglyceride homeostasis(GO:0035356)
0.5 4.2 GO:0061484 hematopoietic stem cell homeostasis(GO:0061484)
0.5 2.1 GO:0016078 tRNA catabolic process(GO:0016078)
0.5 2.6 GO:0051005 negative regulation of lipoprotein lipase activity(GO:0051005)
0.5 4.6 GO:0051503 adenine nucleotide transport(GO:0051503)
0.5 2.6 GO:0031022 nuclear migration along microfilament(GO:0031022)
0.5 1.5 GO:0001180 transcription initiation from RNA polymerase I promoter for nuclear large rRNA transcript(GO:0001180)
0.5 2.5 GO:0043504 mitochondrial DNA repair(GO:0043504)
0.5 3.9 GO:1904263 positive regulation of TORC1 signaling(GO:1904263)
0.5 1.5 GO:0033566 gamma-tubulin complex localization(GO:0033566)
0.5 2.4 GO:1905247 positive regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902961) positive regulation of aspartic-type peptidase activity(GO:1905247)
0.5 1.9 GO:2000623 regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000622) negative regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay(GO:2000623)
0.5 1.9 GO:0032053 ciliary basal body organization(GO:0032053)
0.5 2.7 GO:0032929 negative regulation of superoxide anion generation(GO:0032929)
0.5 1.4 GO:0009130 pyrimidine nucleoside monophosphate metabolic process(GO:0009129) pyrimidine nucleoside monophosphate biosynthetic process(GO:0009130)
0.4 2.2 GO:2000210 positive regulation of anoikis(GO:2000210)
0.4 5.3 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.4 1.8 GO:0018201 peptidyl-glycine modification(GO:0018201)
0.4 0.9 GO:2000812 regulation of barbed-end actin filament capping(GO:2000812)
0.4 2.2 GO:1904874 positive regulation of telomerase RNA localization to Cajal body(GO:1904874)
0.4 1.3 GO:0099578 regulation of translation at synapse, modulating synaptic transmission(GO:0099547) regulation of translation at postsynapse, modulating synaptic transmission(GO:0099578) positive regulation of intracellular transport of viral material(GO:1901254)
0.4 7.7 GO:0048642 negative regulation of skeletal muscle tissue development(GO:0048642)
0.4 0.9 GO:0071492 cellular response to UV-A(GO:0071492)
0.4 1.3 GO:0046900 tetrahydrofolylpolyglutamate metabolic process(GO:0046900)
0.4 3.4 GO:0033313 meiotic cell cycle checkpoint(GO:0033313)
0.4 2.5 GO:0034080 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.4 2.5 GO:0009082 branched-chain amino acid biosynthetic process(GO:0009082) leucine biosynthetic process(GO:0009098) valine biosynthetic process(GO:0009099)
0.4 1.7 GO:0002143 tRNA wobble position uridine thiolation(GO:0002143)
0.4 1.5 GO:1904776 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.4 1.5 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.4 4.2 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.4 1.1 GO:0046881 positive regulation of follicle-stimulating hormone secretion(GO:0046881)
0.4 4.1 GO:0006228 UTP biosynthetic process(GO:0006228)
0.4 1.1 GO:0043096 purine nucleobase salvage(GO:0043096)
0.4 11.9 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.4 1.8 GO:0007412 axon target recognition(GO:0007412)
0.4 13.5 GO:0006270 DNA replication initiation(GO:0006270)
0.4 2.5 GO:0001922 B-1 B cell homeostasis(GO:0001922)
0.4 1.1 GO:0098923 positive regulation of circadian sleep/wake cycle, wakefulness(GO:0010841) retrograde trans-synaptic signaling by soluble gas(GO:0098923)
0.4 3.2 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.4 10.2 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.3 1.0 GO:0000101 sulfur amino acid transport(GO:0000101)
0.3 3.8 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.3 1.7 GO:0051142 regulation of NK T cell proliferation(GO:0051140) positive regulation of NK T cell proliferation(GO:0051142)
0.3 0.7 GO:0033128 negative regulation of histone phosphorylation(GO:0033128)
0.3 1.0 GO:0071638 negative regulation of monocyte chemotactic protein-1 production(GO:0071638)
0.3 0.9 GO:0042823 pyridoxal phosphate biosynthetic process(GO:0042823)
0.3 0.9 GO:0072321 chaperone-mediated protein transport(GO:0072321)
0.3 3.4 GO:0045719 negative regulation of glycogen biosynthetic process(GO:0045719)
0.3 3.4 GO:0001842 neural fold formation(GO:0001842)
0.3 3.1 GO:0007168 receptor guanylyl cyclase signaling pathway(GO:0007168)
0.3 1.2 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.3 0.9 GO:1904882 telomerase catalytic core complex assembly(GO:1904868) regulation of telomerase catalytic core complex assembly(GO:1904882) positive regulation of telomerase catalytic core complex assembly(GO:1904884)
0.3 1.2 GO:0035246 peptidyl-arginine N-methylation(GO:0035246)
0.3 2.4 GO:0000076 DNA replication checkpoint(GO:0000076)
0.3 0.9 GO:1902809 regulation of skeletal muscle fiber differentiation(GO:1902809)
0.3 1.2 GO:2000017 positive regulation of determination of dorsal identity(GO:2000017)
0.3 8.5 GO:0046852 positive regulation of bone resorption(GO:0045780) positive regulation of bone remodeling(GO:0046852)
0.3 1.5 GO:0072429 response to intra-S DNA damage checkpoint signaling(GO:0072429)
0.3 0.9 GO:0019343 cysteine biosynthetic process via cystathionine(GO:0019343)
0.3 1.2 GO:0006975 DNA damage induced protein phosphorylation(GO:0006975)
0.3 0.9 GO:0038001 paracrine signaling(GO:0038001) tertiary branching involved in mammary gland duct morphogenesis(GO:0060748)
0.3 3.0 GO:0030490 maturation of SSU-rRNA(GO:0030490)
0.3 1.9 GO:0010668 ectodermal cell differentiation(GO:0010668)
0.3 1.7 GO:0015822 ornithine transport(GO:0015822)
0.3 1.9 GO:0070601 centromeric sister chromatid cohesion(GO:0070601)
0.3 1.4 GO:0090038 negative regulation of protein kinase C signaling(GO:0090038)
0.3 0.5 GO:1901857 positive regulation of cellular respiration(GO:1901857)
0.3 2.4 GO:2000781 positive regulation of double-strand break repair(GO:2000781)
0.3 1.9 GO:0015862 uridine transport(GO:0015862)
0.3 2.4 GO:0006362 transcription elongation from RNA polymerase I promoter(GO:0006362)
0.3 1.0 GO:0034724 DNA replication-independent nucleosome organization(GO:0034724)
0.3 0.5 GO:0000320 re-entry into mitotic cell cycle(GO:0000320)
0.3 4.6 GO:0006744 ubiquinone biosynthetic process(GO:0006744)
0.3 2.3 GO:0001522 pseudouridine synthesis(GO:0001522)
0.3 3.1 GO:2000507 positive regulation of energy homeostasis(GO:2000507)
0.3 1.3 GO:0021637 trigeminal nerve morphogenesis(GO:0021636) trigeminal nerve structural organization(GO:0021637) semaphorin-plexin signaling pathway involved in axon guidance(GO:1902287)
0.3 3.0 GO:0043247 telomere maintenance in response to DNA damage(GO:0043247)
0.2 1.0 GO:0070889 platelet alpha granule organization(GO:0070889)
0.2 0.5 GO:0000965 mitochondrial RNA 3'-end processing(GO:0000965)
0.2 1.9 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
0.2 0.7 GO:0034238 macrophage fusion(GO:0034238)
0.2 0.7 GO:1990928 response to amino acid starvation(GO:1990928)
0.2 0.7 GO:0070634 transepithelial ammonium transport(GO:0070634)
0.2 0.7 GO:0060399 positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.2 1.2 GO:0061073 ciliary body morphogenesis(GO:0061073)
0.2 1.4 GO:0060178 regulation of exocyst localization(GO:0060178)
0.2 0.7 GO:1904933 regulation of cell proliferation in midbrain(GO:1904933)
0.2 0.7 GO:0044337 canonical Wnt signaling pathway involved in positive regulation of apoptotic process(GO:0044337)
0.2 0.6 GO:0008612 peptidyl-lysine modification to peptidyl-hypusine(GO:0008612)
0.2 1.3 GO:0045917 positive regulation of complement activation(GO:0045917) positive regulation of protein activation cascade(GO:2000259)
0.2 0.2 GO:0034971 histone H3-R17 methylation(GO:0034971)
0.2 0.6 GO:0006931 substrate-dependent cell migration, cell attachment to substrate(GO:0006931)
0.2 2.1 GO:0099515 actin filament-based transport(GO:0099515)
0.2 0.8 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
0.2 7.0 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.2 1.2 GO:0045905 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.2 0.2 GO:1900368 regulation of RNA interference(GO:1900368)
0.2 2.6 GO:0031581 hemidesmosome assembly(GO:0031581)
0.2 2.6 GO:0051292 nuclear pore complex assembly(GO:0051292)
0.2 1.4 GO:1902416 positive regulation of mRNA binding(GO:1902416)
0.2 0.4 GO:0045869 negative regulation of single stranded viral RNA replication via double stranded DNA intermediate(GO:0045869)
0.2 0.6 GO:0075525 viral translational termination-reinitiation(GO:0075525)
0.2 3.7 GO:0060081 membrane hyperpolarization(GO:0060081)
0.2 1.5 GO:0034316 negative regulation of Arp2/3 complex-mediated actin nucleation(GO:0034316)
0.2 4.0 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.2 0.6 GO:0007000 nucleolus organization(GO:0007000)
0.2 1.1 GO:2000505 regulation of energy homeostasis(GO:2000505)
0.2 0.4 GO:0000720 pyrimidine dimer repair by nucleotide-excision repair(GO:0000720)
0.2 1.7 GO:0019852 L-ascorbic acid metabolic process(GO:0019852)
0.2 0.6 GO:0043686 co-translational protein modification(GO:0043686)
0.2 0.6 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.2 0.4 GO:0010032 meiotic chromosome condensation(GO:0010032)
0.2 5.5 GO:0043252 sodium-independent organic anion transport(GO:0043252)
0.2 1.1 GO:0051088 PMA-inducible membrane protein ectodomain proteolysis(GO:0051088)
0.2 0.4 GO:0046098 guanine metabolic process(GO:0046098)
0.2 1.5 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.2 0.7 GO:1902037 negative regulation of hematopoietic stem cell differentiation(GO:1902037)
0.2 1.4 GO:1900264 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.2 2.5 GO:0007076 mitotic chromosome condensation(GO:0007076)
0.2 0.5 GO:0042275 error-free postreplication DNA repair(GO:0042275)
0.2 3.2 GO:0009303 rRNA transcription(GO:0009303)
0.2 1.6 GO:0070131 positive regulation of mitochondrial translation(GO:0070131)
0.2 0.2 GO:0042256 mature ribosome assembly(GO:0042256)
0.2 1.0 GO:0006450 regulation of translational fidelity(GO:0006450)
0.2 5.1 GO:0034723 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.2 3.5 GO:0031571 mitotic G1 DNA damage checkpoint(GO:0031571)
0.2 1.0 GO:0072553 terminal button organization(GO:0072553)
0.2 5.4 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.2 8.9 GO:0006364 rRNA processing(GO:0006364)
0.2 1.1 GO:0000054 ribosomal subunit export from nucleus(GO:0000054) ribosome localization(GO:0033750) establishment of ribosome localization(GO:0033753)
0.2 3.2 GO:0046033 AMP metabolic process(GO:0046033)
0.2 2.1 GO:1902715 positive regulation of interferon-gamma secretion(GO:1902715)
0.2 0.5 GO:0009113 purine nucleobase biosynthetic process(GO:0009113)
0.2 1.1 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.2 3.6 GO:0032933 response to sterol depletion(GO:0006991) SREBP signaling pathway(GO:0032933) cellular response to sterol depletion(GO:0071501)
0.2 2.8 GO:0035414 negative regulation of catenin import into nucleus(GO:0035414)
0.2 0.6 GO:0006290 pyrimidine dimer repair(GO:0006290)
0.1 0.6 GO:0030311 poly-N-acetyllactosamine metabolic process(GO:0030309) poly-N-acetyllactosamine biosynthetic process(GO:0030311)
0.1 1.5 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.1 0.7 GO:0010735 positive regulation of transcription via serum response element binding(GO:0010735)
0.1 0.3 GO:0072054 renal outer medulla development(GO:0072054)
0.1 0.4 GO:1990167 protein K6-linked deubiquitination(GO:0044313) protein K27-linked deubiquitination(GO:1990167)
0.1 0.7 GO:0018343 protein farnesylation(GO:0018343)
0.1 0.4 GO:1900157 regulation of bone mineralization involved in bone maturation(GO:1900157)
0.1 1.6 GO:0035330 regulation of hippo signaling(GO:0035330)
0.1 2.1 GO:0043457 regulation of cellular respiration(GO:0043457)
0.1 0.4 GO:0003360 brainstem development(GO:0003360)
0.1 2.2 GO:0000212 meiotic spindle organization(GO:0000212)
0.1 0.6 GO:0042347 negative regulation of NF-kappaB import into nucleus(GO:0042347)
0.1 1.1 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.1 0.3 GO:0002191 cap-dependent translational initiation(GO:0002191)
0.1 0.4 GO:0000491 small nucleolar ribonucleoprotein complex assembly(GO:0000491) box C/D snoRNP assembly(GO:0000492)
0.1 0.5 GO:0070459 prolactin secretion(GO:0070459)
0.1 0.7 GO:0006868 glutamine transport(GO:0006868)
0.1 0.4 GO:1902310 positive regulation of peptidyl-serine dephosphorylation(GO:1902310)
0.1 0.7 GO:0051987 positive regulation of attachment of spindle microtubules to kinetochore(GO:0051987)
0.1 0.5 GO:0070272 proton-transporting ATP synthase complex assembly(GO:0043461) proton-transporting ATP synthase complex biogenesis(GO:0070272)
0.1 0.5 GO:1903033 regulation of microtubule plus-end binding(GO:1903031) positive regulation of microtubule plus-end binding(GO:1903033)
0.1 0.5 GO:0071672 negative regulation of smooth muscle cell chemotaxis(GO:0071672)
0.1 0.5 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.1 1.3 GO:0015791 polyol transport(GO:0015791)
0.1 0.4 GO:0016256 N-glycan processing to lysosome(GO:0016256)
0.1 1.0 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.1 0.4 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.1 1.4 GO:0098953 receptor diffusion trapping(GO:0098953) postsynaptic neurotransmitter receptor diffusion trapping(GO:0098970) neurotransmitter receptor diffusion trapping(GO:0099628)
0.1 3.7 GO:0009072 aromatic amino acid family metabolic process(GO:0009072)
0.1 0.2 GO:0033484 nitric oxide homeostasis(GO:0033484)
0.1 1.0 GO:0016560 protein import into peroxisome matrix, docking(GO:0016560)
0.1 1.3 GO:0042118 endothelial cell activation(GO:0042118)
0.1 0.7 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.1 0.5 GO:1903422 negative regulation of synaptic vesicle recycling(GO:1903422)
0.1 0.5 GO:0030576 Cajal body organization(GO:0030576)
0.1 1.9 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.1 1.1 GO:0048742 regulation of skeletal muscle fiber development(GO:0048742)
0.1 0.8 GO:0010587 miRNA catabolic process(GO:0010587)
0.1 1.0 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.1 1.9 GO:0071392 cellular response to estradiol stimulus(GO:0071392)
0.1 0.7 GO:0000414 regulation of histone H3-K36 methylation(GO:0000414)
0.1 0.8 GO:0098909 regulation of cardiac muscle cell action potential involved in regulation of contraction(GO:0098909)
0.1 4.5 GO:0006414 translational elongation(GO:0006414)
0.1 0.7 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.1 0.6 GO:0003383 apical constriction(GO:0003383)
0.1 1.2 GO:0006474 N-terminal protein amino acid acetylation(GO:0006474)
0.1 0.2 GO:0007161 calcium-independent cell-matrix adhesion(GO:0007161)
0.1 0.3 GO:0030043 actin filament fragmentation(GO:0030043)
0.1 0.7 GO:0035948 positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter(GO:0035948)
0.1 0.6 GO:1903691 positive regulation of wound healing, spreading of epidermal cells(GO:1903691)
0.1 0.3 GO:0071930 negative regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071930)
0.1 1.7 GO:0070816 phosphorylation of RNA polymerase II C-terminal domain(GO:0070816)
0.1 0.5 GO:0010452 histone H3-K36 methylation(GO:0010452)
0.1 0.4 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.1 0.3 GO:0006409 tRNA export from nucleus(GO:0006409) tRNA-containing ribonucleoprotein complex export from nucleus(GO:0071431)
0.1 0.5 GO:0015889 cobalamin transport(GO:0015889)
0.1 0.5 GO:0006543 glutamine catabolic process(GO:0006543)
0.1 1.3 GO:0016322 neuron remodeling(GO:0016322)
0.1 0.6 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.1 0.7 GO:0060528 secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development(GO:0060528)
0.1 0.6 GO:0006369 termination of RNA polymerase II transcription(GO:0006369)
0.1 0.3 GO:1902548 regulation of endothelial tube morphogenesis(GO:1901509) regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202) negative regulation of cellular response to vascular endothelial growth factor stimulus(GO:1902548)
0.1 0.3 GO:0010641 activation of plasma proteins involved in acute inflammatory response(GO:0002541) positive regulation of platelet-derived growth factor receptor signaling pathway(GO:0010641)
0.1 0.4 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.1 0.4 GO:1901299 negative regulation of hydrogen peroxide-mediated programmed cell death(GO:1901299)
0.1 1.4 GO:0008272 sulfate transport(GO:0008272)
0.1 2.2 GO:0006515 misfolded or incompletely synthesized protein catabolic process(GO:0006515)
0.1 0.4 GO:0033140 negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140)
0.1 0.3 GO:1902174 positive regulation of keratinocyte apoptotic process(GO:1902174)
0.1 3.2 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026) regulation of microtubule depolymerization(GO:0031114)
0.1 1.3 GO:2001273 regulation of glucose import in response to insulin stimulus(GO:2001273)
0.1 0.3 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.1 1.3 GO:0031987 locomotion involved in locomotory behavior(GO:0031987)
0.1 1.6 GO:0051205 protein insertion into membrane(GO:0051205)
0.1 0.9 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.1 0.6 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.1 0.2 GO:0009786 regulation of asymmetric cell division(GO:0009786)
0.1 0.5 GO:0038018 Wnt receptor catabolic process(GO:0038018)
0.1 0.8 GO:0034501 protein localization to kinetochore(GO:0034501)
0.1 0.3 GO:0048298 regulation of isotype switching to IgA isotypes(GO:0048296) positive regulation of isotype switching to IgA isotypes(GO:0048298)
0.1 1.3 GO:0043567 regulation of insulin-like growth factor receptor signaling pathway(GO:0043567)
0.1 0.4 GO:1903553 positive regulation of extracellular exosome assembly(GO:1903553)
0.1 0.6 GO:0034143 regulation of toll-like receptor 4 signaling pathway(GO:0034143)
0.1 1.4 GO:0051654 establishment of mitochondrion localization(GO:0051654)
0.1 0.9 GO:0035563 positive regulation of chromatin binding(GO:0035563)
0.1 0.4 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.1 0.8 GO:0019368 fatty acid elongation, saturated fatty acid(GO:0019367) fatty acid elongation, unsaturated fatty acid(GO:0019368) fatty acid elongation, monounsaturated fatty acid(GO:0034625) fatty acid elongation, polyunsaturated fatty acid(GO:0034626)
0.1 0.8 GO:0042532 negative regulation of tyrosine phosphorylation of STAT protein(GO:0042532)
0.1 2.6 GO:0006284 base-excision repair(GO:0006284)
0.1 1.0 GO:0007141 male meiosis I(GO:0007141)
0.1 0.2 GO:1902915 negative regulation of protein K63-linked ubiquitination(GO:1900045) negative regulation of protein polyubiquitination(GO:1902915) regulation of interleukin-17 secretion(GO:1905076) negative regulation of interleukin-17 secretion(GO:1905077)
0.1 0.1 GO:0036166 phenotypic switching(GO:0036166) cellular response to cocaine(GO:0071314)
0.1 1.6 GO:0002052 positive regulation of neuroblast proliferation(GO:0002052)
0.1 0.4 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.1 1.1 GO:0000338 protein deneddylation(GO:0000338)
0.1 3.5 GO:0031122 cytoplasmic microtubule organization(GO:0031122)
0.1 0.8 GO:0018126 protein hydroxylation(GO:0018126)
0.1 0.6 GO:0018095 protein polyglutamylation(GO:0018095)
0.1 0.6 GO:0033292 T-tubule organization(GO:0033292) protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371)
0.1 0.6 GO:0042989 sequestering of actin monomers(GO:0042989)
0.1 0.2 GO:0019464 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.1 0.2 GO:2000196 positive regulation of female gonad development(GO:2000196) positive regulation of progesterone secretion(GO:2000872)
0.1 0.7 GO:0002726 positive regulation of T cell cytokine production(GO:0002726)
0.1 2.7 GO:0050850 positive regulation of calcium-mediated signaling(GO:0050850)
0.1 1.3 GO:0010842 retina layer formation(GO:0010842)
0.1 0.4 GO:0006741 NADP biosynthetic process(GO:0006741)
0.1 0.3 GO:1990253 cellular response to leucine starvation(GO:1990253)
0.1 0.7 GO:0002347 response to tumor cell(GO:0002347)
0.1 1.1 GO:1900078 positive regulation of cellular response to insulin stimulus(GO:1900078)
0.1 0.8 GO:0071420 cellular response to histamine(GO:0071420)
0.1 0.3 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.1 0.2 GO:0021986 epithalamus development(GO:0021538) habenula development(GO:0021986)
0.1 1.2 GO:0002115 store-operated calcium entry(GO:0002115)
0.1 0.6 GO:0032308 positive regulation of prostaglandin secretion(GO:0032308)
0.1 2.4 GO:0042771 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:0042771)
0.1 0.4 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.1 0.4 GO:0015871 choline transport(GO:0015871)
0.1 2.4 GO:0070936 protein K48-linked ubiquitination(GO:0070936)
0.1 0.4 GO:0010991 regulation of SMAD protein complex assembly(GO:0010990) negative regulation of SMAD protein complex assembly(GO:0010991)
0.1 1.0 GO:0050650 chondroitin sulfate proteoglycan biosynthetic process(GO:0050650)
0.1 0.9 GO:0007019 microtubule depolymerization(GO:0007019)
0.1 0.3 GO:0008355 olfactory learning(GO:0008355)
0.0 2.9 GO:0009060 aerobic respiration(GO:0009060)
0.0 2.3 GO:0021680 cerebellar Purkinje cell layer development(GO:0021680)
0.0 0.2 GO:0071910 determination of pancreatic left/right asymmetry(GO:0035469) determination of liver left/right asymmetry(GO:0071910)
0.0 0.3 GO:0032776 DNA methylation on cytosine(GO:0032776)
0.0 0.1 GO:0006435 threonyl-tRNA aminoacylation(GO:0006435)
0.0 0.4 GO:0045618 positive regulation of keratinocyte differentiation(GO:0045618)
0.0 0.2 GO:1902340 telomeric heterochromatin assembly(GO:0031509) negative regulation of chromosome condensation(GO:1902340)
0.0 0.1 GO:1903294 regulation of glutamate secretion, neurotransmission(GO:1903294) positive regulation of glutamate secretion, neurotransmission(GO:1903296)
0.0 3.2 GO:0006334 nucleosome assembly(GO:0006334)
0.0 0.1 GO:0007144 female meiosis I(GO:0007144)
0.0 1.1 GO:0008209 androgen metabolic process(GO:0008209)
0.0 0.4 GO:0035269 protein O-linked mannosylation(GO:0035269)
0.0 1.1 GO:0006910 phagocytosis, recognition(GO:0006910)
0.0 0.9 GO:1904030 negative regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045736) negative regulation of cyclin-dependent protein kinase activity(GO:1904030)
0.0 1.6 GO:0006446 regulation of translational initiation(GO:0006446)
0.0 0.5 GO:0014823 response to activity(GO:0014823)
0.0 0.4 GO:0042407 cristae formation(GO:0042407)
0.0 0.3 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.0 2.6 GO:0051865 protein autoubiquitination(GO:0051865)
0.0 0.1 GO:0061470 T follicular helper cell differentiation(GO:0061470)
0.0 0.9 GO:1990126 retrograde transport, endosome to plasma membrane(GO:1990126)
0.0 0.2 GO:0048170 positive regulation of long-term neuronal synaptic plasticity(GO:0048170)
0.0 0.6 GO:0044146 negative regulation of growth of symbiont in host(GO:0044130) negative regulation of growth of symbiont involved in interaction with host(GO:0044146)
0.0 0.2 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.0 0.1 GO:1901069 guanosine-containing compound catabolic process(GO:1901069)
0.0 0.7 GO:0042753 positive regulation of circadian rhythm(GO:0042753)
0.0 0.4 GO:0043496 regulation of protein homodimerization activity(GO:0043496)
0.0 0.2 GO:1901029 negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
0.0 0.5 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.3 GO:0090177 establishment of planar polarity involved in neural tube closure(GO:0090177)
0.0 0.5 GO:1902187 negative regulation of viral release from host cell(GO:1902187)
0.0 1.9 GO:0048477 oogenesis(GO:0048477)
0.0 0.2 GO:0051901 positive regulation of mitochondrial depolarization(GO:0051901)
0.0 0.2 GO:0051823 regulation of synapse structural plasticity(GO:0051823)
0.0 0.3 GO:1902949 positive regulation of tau-protein kinase activity(GO:1902949)
0.0 0.9 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.1 GO:0072531 pyrimidine-containing compound transmembrane transport(GO:0072531)
0.0 0.1 GO:0030974 thiamine pyrophosphate transport(GO:0030974)
0.0 0.5 GO:0000920 cell separation after cytokinesis(GO:0000920)
0.0 0.3 GO:1901250 regulation of lung goblet cell differentiation(GO:1901249) negative regulation of lung goblet cell differentiation(GO:1901250)
0.0 0.2 GO:0061113 pancreas morphogenesis(GO:0061113)
0.0 0.6 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 0.2 GO:0035878 nail development(GO:0035878)
0.0 0.1 GO:0042636 negative regulation of hair cycle(GO:0042636)
0.0 1.1 GO:0030071 regulation of mitotic metaphase/anaphase transition(GO:0030071) regulation of metaphase/anaphase transition of cell cycle(GO:1902099)
0.0 2.0 GO:0030032 lamellipodium assembly(GO:0030032)
0.0 0.3 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.2 GO:0010807 regulation of synaptic vesicle priming(GO:0010807)
0.0 0.3 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.0 0.5 GO:2000651 positive regulation of sodium ion transmembrane transporter activity(GO:2000651)
0.0 0.4 GO:0007097 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.0 0.1 GO:0014028 notochord formation(GO:0014028)
0.0 0.1 GO:0010832 negative regulation of myotube differentiation(GO:0010832)
0.0 0.5 GO:0040034 regulation of development, heterochronic(GO:0040034)
0.0 0.3 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.7 GO:0038202 TORC1 signaling(GO:0038202)
0.0 0.4 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.3 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.0 0.2 GO:0045075 interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.0 0.6 GO:0060285 cilium or flagellum-dependent cell motility(GO:0001539) cilium-dependent cell motility(GO:0060285)
0.0 2.0 GO:0051092 positive regulation of NF-kappaB transcription factor activity(GO:0051092)
0.0 0.4 GO:2000279 negative regulation of DNA biosynthetic process(GO:2000279)
0.0 0.9 GO:0030901 midbrain development(GO:0030901)
0.0 0.2 GO:0006477 protein sulfation(GO:0006477)
0.0 0.9 GO:0006826 iron ion transport(GO:0006826)
0.0 0.1 GO:0003065 positive regulation of heart rate by epinephrine(GO:0003065)
0.0 0.2 GO:0090141 positive regulation of mitochondrial fission(GO:0090141)
0.0 0.2 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.0 0.1 GO:0034397 telomere localization(GO:0034397) meiotic telomere clustering(GO:0045141) chromosome localization to nuclear envelope involved in homologous chromosome segregation(GO:0090220)
0.0 0.2 GO:0001672 regulation of chromatin assembly or disassembly(GO:0001672)
0.0 0.5 GO:0035329 hippo signaling(GO:0035329)
0.0 0.3 GO:0016180 snRNA processing(GO:0016180)
0.0 0.5 GO:0050892 intestinal absorption(GO:0050892)
0.0 0.4 GO:0031954 positive regulation of protein autophosphorylation(GO:0031954)
0.0 0.3 GO:0006308 DNA catabolic process(GO:0006308)
0.0 0.1 GO:0045657 positive regulation of monocyte differentiation(GO:0045657)
0.0 0.5 GO:0015813 L-glutamate transport(GO:0015813)
0.0 0.3 GO:0019430 removal of superoxide radicals(GO:0019430)
0.0 0.2 GO:0031547 brain-derived neurotrophic factor receptor signaling pathway(GO:0031547)
0.0 0.7 GO:0048146 positive regulation of fibroblast proliferation(GO:0048146)
0.0 0.4 GO:0051560 mitochondrial calcium ion homeostasis(GO:0051560)
0.0 0.3 GO:0060445 branching involved in salivary gland morphogenesis(GO:0060445)
0.0 0.5 GO:0003333 amino acid transmembrane transport(GO:0003333)
0.0 0.8 GO:0006400 tRNA modification(GO:0006400)
0.0 0.1 GO:0014053 negative regulation of gamma-aminobutyric acid secretion(GO:0014053) negative regulation of serotonin secretion(GO:0014063)
0.0 1.7 GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules(GO:0007156)
0.0 0.3 GO:0046457 prostaglandin biosynthetic process(GO:0001516) prostanoid biosynthetic process(GO:0046457)
0.0 0.1 GO:0032380 regulation of intracellular lipid transport(GO:0032377) regulation of intracellular sterol transport(GO:0032380) regulation of intracellular cholesterol transport(GO:0032383)
0.0 0.2 GO:0001886 endothelial cell morphogenesis(GO:0001886)
0.0 0.9 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.0 0.1 GO:0090210 regulation of establishment of blood-brain barrier(GO:0090210) negative regulation of establishment of blood-brain barrier(GO:0090212)
0.0 0.2 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.4 GO:0001913 T cell mediated cytotoxicity(GO:0001913)
0.0 0.7 GO:0045600 positive regulation of fat cell differentiation(GO:0045600)
0.0 0.4 GO:0010107 potassium ion import(GO:0010107)
0.0 0.4 GO:0046677 response to antibiotic(GO:0046677)
0.0 0.5 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.3 GO:0045116 protein neddylation(GO:0045116)
0.0 0.1 GO:0001956 positive regulation of neurotransmitter secretion(GO:0001956)
0.0 0.1 GO:0048664 neuron fate determination(GO:0048664)
0.0 0.1 GO:0035093 spermatogenesis, exchange of chromosomal proteins(GO:0035093)
0.0 0.3 GO:0045071 negative regulation of viral genome replication(GO:0045071)
0.0 0.0 GO:0034134 toll-like receptor 2 signaling pathway(GO:0034134)
0.0 0.5 GO:0050829 defense response to Gram-negative bacterium(GO:0050829)
0.0 0.3 GO:0040015 negative regulation of multicellular organism growth(GO:0040015)
0.0 0.0 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.0 1.3 GO:1990830 response to leukemia inhibitory factor(GO:1990823) cellular response to leukemia inhibitory factor(GO:1990830)
0.0 0.3 GO:0071479 cellular response to ionizing radiation(GO:0071479)
0.0 0.1 GO:1903182 regulation of SUMO transferase activity(GO:1903182) positive regulation of SUMO transferase activity(GO:1903755)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
3.3 23.0 GO:0031428 box C/D snoRNP complex(GO:0031428)
2.5 12.4 GO:0044611 nuclear pore inner ring(GO:0044611)
2.0 15.6 GO:0031415 NatA complex(GO:0031415)
1.9 5.6 GO:0097135 cyclin E2-CDK2 complex(GO:0097135)
1.7 5.1 GO:0033186 CAF-1 complex(GO:0033186)
1.6 6.5 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
1.4 5.6 GO:0008537 proteasome activator complex(GO:0008537)
1.2 8.6 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
1.2 6.1 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
1.2 3.5 GO:0005967 mitochondrial pyruvate dehydrogenase complex(GO:0005967)
1.2 5.8 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
1.1 6.6 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
1.1 5.4 GO:0001651 dense fibrillar component(GO:0001651)
1.1 6.5 GO:0005826 actomyosin contractile ring(GO:0005826)
1.1 3.2 GO:0031074 nucleocytoplasmic shuttling complex(GO:0031074)
1.0 3.9 GO:0090537 CERF complex(GO:0090537)
0.8 3.2 GO:0070552 BRISC complex(GO:0070552)
0.8 6.0 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.7 5.3 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.7 2.6 GO:0090661 box H/ACA telomerase RNP complex(GO:0090661)
0.7 6.5 GO:0070545 PeBoW complex(GO:0070545)
0.7 3.3 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.6 4.2 GO:0070761 pre-snoRNP complex(GO:0070761)
0.6 4.1 GO:0097452 GAIT complex(GO:0097452)
0.6 1.7 GO:0017109 glutamate-cysteine ligase complex(GO:0017109)
0.6 12.7 GO:0030686 90S preribosome(GO:0030686)
0.5 3.1 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.5 3.0 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.5 2.9 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.5 6.0 GO:0042555 MCM complex(GO:0042555)
0.4 5.6 GO:0032797 SMN complex(GO:0032797)
0.4 1.3 GO:0035101 FACT complex(GO:0035101)
0.4 2.1 GO:1990761 growth cone lamellipodium(GO:1990761)
0.4 10.7 GO:0005680 anaphase-promoting complex(GO:0005680)
0.4 2.0 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.4 6.5 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.4 5.2 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.4 2.0 GO:0070937 CRD-mediated mRNA stability complex(GO:0070937)
0.4 1.5 GO:0097255 R2TP complex(GO:0097255)
0.4 1.1 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.4 3.2 GO:0000801 central element(GO:0000801)
0.4 3.5 GO:0016272 prefoldin complex(GO:0016272)
0.3 2.4 GO:0030896 checkpoint clamp complex(GO:0030896)
0.3 2.4 GO:0001740 Barr body(GO:0001740)
0.3 2.4 GO:0070695 FHF complex(GO:0070695)
0.3 16.1 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.3 7.2 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.3 2.0 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.3 2.6 GO:0030314 junctional membrane complex(GO:0030314)
0.3 1.9 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.3 4.4 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.3 3.4 GO:0005642 annulate lamellae(GO:0005642)
0.3 3.8 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.3 2.0 GO:0005638 lamin filament(GO:0005638)
0.3 1.1 GO:0043511 inhibin complex(GO:0043511)
0.3 2.5 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.3 1.1 GO:0033553 rDNA heterochromatin(GO:0033553)
0.3 5.3 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.3 0.8 GO:0030905 retromer, tubulation complex(GO:0030905)
0.3 1.1 GO:0031084 BLOC-2 complex(GO:0031084)
0.3 10.2 GO:0015030 Cajal body(GO:0015030)
0.3 1.4 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.3 2.4 GO:0097512 cardiac myofibril(GO:0097512)
0.3 4.2 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.3 2.6 GO:0005883 neurofilament(GO:0005883)
0.3 1.0 GO:0030906 retromer, cargo-selective complex(GO:0030906)
0.2 2.2 GO:0000439 core TFIIH complex(GO:0000439)
0.2 2.9 GO:0032040 small-subunit processome(GO:0032040)
0.2 1.2 GO:0071547 piP-body(GO:0071547)
0.2 3.6 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.2 0.9 GO:0099522 region of cytosol(GO:0099522) postsynaptic cytosol(GO:0099524)
0.2 3.2 GO:0030061 mitochondrial crista(GO:0030061)
0.2 4.5 GO:0046930 pore complex(GO:0046930)
0.2 1.4 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.2 0.9 GO:0070032 synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex(GO:0070032)
0.2 1.1 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.2 0.9 GO:0005606 laminin-1 complex(GO:0005606) laminin-10 complex(GO:0043259)
0.2 0.6 GO:0031510 SUMO activating enzyme complex(GO:0031510)
0.2 2.6 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.2 2.2 GO:0031931 TORC1 complex(GO:0031931)
0.2 3.2 GO:0031083 BLOC-1 complex(GO:0031083)
0.2 2.9 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.2 3.0 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.2 1.8 GO:0034709 methylosome(GO:0034709)
0.2 0.5 GO:0097543 ciliary inversin compartment(GO:0097543)
0.2 8.3 GO:0009295 nucleoid(GO:0009295) mitochondrial nucleoid(GO:0042645)
0.2 2.1 GO:1990635 proximal dendrite(GO:1990635)
0.2 0.5 GO:0031372 UBC13-MMS2 complex(GO:0031372)
0.2 13.0 GO:0022626 cytosolic ribosome(GO:0022626)
0.2 3.9 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.2 2.1 GO:0070852 cell body fiber(GO:0070852)
0.2 0.7 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.2 1.4 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.2 0.5 GO:0070985 TFIIK complex(GO:0070985)
0.2 2.9 GO:0030914 STAGA complex(GO:0030914)
0.1 0.1 GO:0034448 EGO complex(GO:0034448)
0.1 0.7 GO:0071556 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.1 0.4 GO:0031533 mRNA cap methyltransferase complex(GO:0031533)
0.1 8.7 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.1 2.8 GO:0031527 filopodium membrane(GO:0031527)
0.1 1.0 GO:0017071 intracellular cyclic nucleotide activated cation channel complex(GO:0017071)
0.1 1.2 GO:0000243 commitment complex(GO:0000243)
0.1 0.5 GO:0030981 cortical microtubule cytoskeleton(GO:0030981)
0.1 0.9 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.1 4.9 GO:0060077 inhibitory synapse(GO:0060077)
0.1 1.6 GO:0000153 cytoplasmic ubiquitin ligase complex(GO:0000153)
0.1 18.6 GO:0001650 fibrillar center(GO:0001650)
0.1 0.9 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.1 0.7 GO:0031258 lamellipodium membrane(GO:0031258)
0.1 1.1 GO:0097197 tetraspanin-enriched microdomain(GO:0097197)
0.1 2.0 GO:0031045 dense core granule(GO:0031045)
0.1 0.5 GO:0071817 MMXD complex(GO:0071817)
0.1 1.9 GO:0035253 ciliary rootlet(GO:0035253)
0.1 0.7 GO:0070847 core mediator complex(GO:0070847)
0.1 0.7 GO:1990023 mitotic spindle midzone(GO:1990023)
0.1 0.6 GO:0098560 cytoplasmic side of late endosome membrane(GO:0098560)
0.1 0.2 GO:0070044 synaptobrevin 2-SNAP-25-syntaxin-1a complex(GO:0070044)
0.1 5.6 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.1 0.7 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.1 3.1 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.1 0.4 GO:0097059 CNTFR-CLCF1 complex(GO:0097059)
0.1 6.5 GO:0005657 replication fork(GO:0005657)
0.1 1.1 GO:0042571 immunoglobulin complex, circulating(GO:0042571)
0.1 1.3 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.1 0.7 GO:0000127 transcription factor TFIIIC complex(GO:0000127)
0.1 0.7 GO:0031466 Cul5-RING ubiquitin ligase complex(GO:0031466)
0.1 0.4 GO:0043293 apoptosome(GO:0043293)
0.1 1.8 GO:0030056 hemidesmosome(GO:0030056)
0.1 4.2 GO:0031228 integral component of Golgi membrane(GO:0030173) intrinsic component of Golgi membrane(GO:0031228)
0.1 0.9 GO:0042405 nuclear inclusion body(GO:0042405)
0.1 2.6 GO:0005921 gap junction(GO:0005921)
0.1 0.9 GO:0031080 nuclear pore outer ring(GO:0031080)
0.1 4.5 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.1 1.4 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.1 1.2 GO:0005686 U2 snRNP(GO:0005686)
0.1 4.6 GO:0015934 large ribosomal subunit(GO:0015934)
0.1 1.8 GO:0000930 gamma-tubulin complex(GO:0000930)
0.1 0.3 GO:0072487 MSL complex(GO:0072487)
0.1 1.1 GO:0097539 ciliary transition fiber(GO:0097539)
0.1 0.3 GO:0032389 MutLalpha complex(GO:0032389)
0.1 0.4 GO:0009331 glycerol-3-phosphate dehydrogenase complex(GO:0009331)
0.1 2.4 GO:0005840 ribosome(GO:0005840)
0.1 0.8 GO:0044452 nucleolar part(GO:0044452)
0.1 0.8 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.1 1.3 GO:0097431 mitotic spindle pole(GO:0097431)
0.1 0.2 GO:0031417 NatC complex(GO:0031417)
0.1 2.2 GO:0033268 node of Ranvier(GO:0033268)
0.1 1.4 GO:0001741 XY body(GO:0001741)
0.1 0.3 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.1 4.3 GO:0072686 mitotic spindle(GO:0072686)
0.1 8.8 GO:0005759 mitochondrial matrix(GO:0005759)
0.1 1.3 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.1 14.9 GO:0031965 nuclear membrane(GO:0031965)
0.1 2.2 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 1.8 GO:0005865 striated muscle thin filament(GO:0005865)
0.1 1.1 GO:0043034 costamere(GO:0043034)
0.1 0.8 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.1 1.6 GO:0001891 phagocytic cup(GO:0001891)
0.1 0.5 GO:0005845 mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.1 0.6 GO:0097546 ciliary base(GO:0097546)
0.1 0.4 GO:0042382 paraspeckles(GO:0042382)
0.1 1.1 GO:0090568 nuclear transcriptional repressor complex(GO:0090568)
0.1 0.6 GO:0005641 nuclear envelope lumen(GO:0005641)
0.1 1.0 GO:0032839 dendrite cytoplasm(GO:0032839)
0.1 1.6 GO:0005876 spindle microtubule(GO:0005876)
0.1 3.7 GO:0017053 transcriptional repressor complex(GO:0017053)
0.1 1.6 GO:0016592 mediator complex(GO:0016592)
0.0 0.8 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 1.2 GO:0097228 sperm principal piece(GO:0097228)
0.0 0.7 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 22.2 GO:0005813 centrosome(GO:0005813)
0.0 0.7 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.9 GO:0061702 inflammasome complex(GO:0061702)
0.0 2.3 GO:0099501 synaptic vesicle membrane(GO:0030672) exocytic vesicle membrane(GO:0099501)
0.0 0.4 GO:0061617 MICOS complex(GO:0061617)
0.0 0.4 GO:0000796 condensin complex(GO:0000796)
0.0 0.5 GO:1990752 microtubule end(GO:1990752)
0.0 2.7 GO:0000776 kinetochore(GO:0000776)
0.0 0.4 GO:0089717 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.0 3.0 GO:0016459 myosin complex(GO:0016459)
0.0 1.5 GO:0010494 cytoplasmic stress granule(GO:0010494)
0.0 0.2 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0 1.7 GO:0000118 histone deacetylase complex(GO:0000118)
0.0 0.2 GO:0071439 clathrin complex(GO:0071439)
0.0 21.3 GO:0005730 nucleolus(GO:0005730)
0.0 0.2 GO:0043203 axon hillock(GO:0043203)
0.0 2.4 GO:0030496 midbody(GO:0030496)
0.0 0.2 GO:0016589 NURF complex(GO:0016589)
0.0 0.5 GO:0035097 histone methyltransferase complex(GO:0035097)
0.0 2.0 GO:0016363 nuclear matrix(GO:0016363)
0.0 0.6 GO:0031430 M band(GO:0031430)
0.0 2.1 GO:0005811 lipid particle(GO:0005811)
0.0 0.2 GO:0071004 U2-type prespliceosome(GO:0071004)
0.0 0.3 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.1 GO:0032300 mismatch repair complex(GO:0032300)
0.0 0.3 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.2 GO:0016442 RISC complex(GO:0016442) RNAi effector complex(GO:0031332)
0.0 1.9 GO:0000784 nuclear chromosome, telomeric region(GO:0000784)
0.0 0.3 GO:0032039 integrator complex(GO:0032039)
0.0 2.1 GO:0072562 blood microparticle(GO:0072562)
0.0 0.4 GO:0031305 intrinsic component of mitochondrial inner membrane(GO:0031304) integral component of mitochondrial inner membrane(GO:0031305)
0.0 2.7 GO:0031225 anchored component of membrane(GO:0031225)
0.0 0.6 GO:0000786 nucleosome(GO:0000786)
0.0 0.0 GO:0045273 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 0.1 GO:0031254 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 1.3 GO:0001725 stress fiber(GO:0001725) contractile actin filament bundle(GO:0097517)
0.0 0.0 GO:1990730 VCP-NSFL1C complex(GO:1990730)
0.0 1.7 GO:0005741 mitochondrial outer membrane(GO:0005741)
0.0 0.1 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.2 GO:0097440 apical dendrite(GO:0097440)
0.0 0.8 GO:0071013 catalytic step 2 spliceosome(GO:0071013)
0.0 0.4 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.9 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.1 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
2.6 12.9 GO:1990190 peptide-glutamate-N-acetyltransferase activity(GO:1990190)
2.5 7.4 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
2.2 13.4 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
2.1 6.3 GO:0008732 threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
1.6 12.6 GO:0001094 TFIID-class transcription factor binding(GO:0001094)
1.4 4.2 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
1.4 4.1 GO:0033680 ATP-dependent DNA/RNA helicase activity(GO:0033680)
1.3 5.0 GO:0000010 trans-hexaprenyltranstransferase activity(GO:0000010) trans-octaprenyltranstransferase activity(GO:0050347)
1.2 4.9 GO:0003875 ADP-ribosylarginine hydrolase activity(GO:0003875)
1.2 4.8 GO:0015232 heme transporter activity(GO:0015232)
1.2 3.5 GO:0004350 glutamate 5-kinase activity(GO:0004349) glutamate-5-semialdehyde dehydrogenase activity(GO:0004350) delta1-pyrroline-5-carboxylate synthetase activity(GO:0017084) amino acid kinase activity(GO:0019202)
1.1 4.6 GO:0004832 valine-tRNA ligase activity(GO:0004832)
1.1 3.4 GO:0003846 2-acylglycerol O-acyltransferase activity(GO:0003846) retinol O-fatty-acyltransferase activity(GO:0050252)
1.1 8.6 GO:0043559 insulin binding(GO:0043559)
1.1 3.2 GO:0009383 rRNA (cytosine-C5-)-methyltransferase activity(GO:0009383)
1.0 9.2 GO:0004331 6-phosphofructo-2-kinase activity(GO:0003873) fructose-2,6-bisphosphate 2-phosphatase activity(GO:0004331)
1.0 3.0 GO:0000401 open form four-way junction DNA binding(GO:0000401) crossed form four-way junction DNA binding(GO:0000402)
1.0 3.0 GO:0008311 double-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008311)
1.0 7.0 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
1.0 4.8 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.9 8.5 GO:0055104 ligase inhibitor activity(GO:0055104) ubiquitin ligase inhibitor activity(GO:1990948)
0.9 2.7 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.9 3.5 GO:0004740 pyruvate dehydrogenase (acetyl-transferring) kinase activity(GO:0004740)
0.9 13.9 GO:1990226 histone methyltransferase binding(GO:1990226)
0.9 2.6 GO:0008176 tRNA (guanine-N7-)-methyltransferase activity(GO:0008176)
0.8 2.5 GO:0031403 lithium ion binding(GO:0031403)
0.7 5.1 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.7 2.1 GO:0000171 ribonuclease MRP activity(GO:0000171)
0.7 5.6 GO:0061133 endopeptidase activator activity(GO:0061133)
0.7 5.5 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.7 10.3 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.7 5.4 GO:0070087 chromo shadow domain binding(GO:0070087)
0.7 4.6 GO:0004767 sphingomyelin phosphodiesterase activity(GO:0004767)
0.6 3.8 GO:0016742 hydroxymethyl-, formyl- and related transferase activity(GO:0016742)
0.6 4.9 GO:0034511 U3 snoRNA binding(GO:0034511)
0.6 1.8 GO:0035851 Krueppel-associated box domain binding(GO:0035851)
0.6 0.6 GO:1990189 peptide-serine-N-acetyltransferase activity(GO:1990189)
0.6 1.7 GO:0004357 glutamate-cysteine ligase activity(GO:0004357)
0.6 2.2 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.5 3.2 GO:1990932 5.8S rRNA binding(GO:1990932)
0.5 4.3 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.5 2.1 GO:0047288 beta-galactoside (CMP) alpha-2,3-sialyltransferase activity(GO:0003836) monosialoganglioside sialyltransferase activity(GO:0047288)
0.5 3.7 GO:0033592 RNA strand annealing activity(GO:0033592)
0.5 10.7 GO:0048027 mRNA 5'-UTR binding(GO:0048027)
0.5 2.5 GO:0008269 JAK pathway signal transduction adaptor activity(GO:0008269)
0.5 12.4 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.5 5.0 GO:0008097 5S rRNA binding(GO:0008097)
0.5 6.9 GO:0019103 pyrimidine nucleotide binding(GO:0019103)
0.5 4.9 GO:0015193 L-proline transmembrane transporter activity(GO:0015193)
0.5 2.4 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.5 3.4 GO:0016428 tRNA (cytosine-5-)-methyltransferase activity(GO:0016428)
0.5 1.4 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.5 7.9 GO:0015643 toxic substance binding(GO:0015643)
0.5 4.5 GO:0051434 BH3 domain binding(GO:0051434)
0.5 0.9 GO:0005237 inhibitory extracellular ligand-gated ion channel activity(GO:0005237)
0.4 3.4 GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.4 1.3 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.4 2.5 GO:0004084 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.4 2.4 GO:0098519 nucleotide phosphatase activity, acting on free nucleotides(GO:0098519)
0.4 2.3 GO:0032027 myosin light chain binding(GO:0032027)
0.4 3.8 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.4 1.5 GO:0031694 alpha-2A adrenergic receptor binding(GO:0031694)
0.4 1.5 GO:0004427 inorganic diphosphatase activity(GO:0004427)
0.4 1.5 GO:0030984 kininogen binding(GO:0030984)
0.4 1.1 GO:0031686 A1 adenosine receptor binding(GO:0031686)
0.4 1.1 GO:0097100 supercoiled DNA binding(GO:0097100)
0.3 4.7 GO:0003688 DNA replication origin binding(GO:0003688)
0.3 2.3 GO:0046976 histone methyltransferase activity (H3-K27 specific)(GO:0046976)
0.3 1.7 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.3 1.3 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.3 2.9 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.3 15.2 GO:0030332 cyclin binding(GO:0030332)
0.3 1.0 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.3 1.6 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.3 2.2 GO:0001162 RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding(GO:0001162)
0.3 1.2 GO:0004176 ATP-dependent peptidase activity(GO:0004176)
0.3 13.8 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.3 0.9 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.3 1.2 GO:0032407 MutSalpha complex binding(GO:0032407)
0.3 9.8 GO:0098632 protein binding involved in cell-cell adhesion(GO:0098632)
0.3 1.2 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.3 0.9 GO:0008192 RNA guanylyltransferase activity(GO:0008192)
0.3 4.2 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.3 6.5 GO:0003746 translation elongation factor activity(GO:0003746)
0.3 2.5 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.3 2.5 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.3 2.8 GO:0070097 delta-catenin binding(GO:0070097)
0.3 1.7 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.3 4.1 GO:0043495 protein anchor(GO:0043495)
0.3 0.8 GO:0004998 transferrin receptor activity(GO:0004998)
0.3 2.4 GO:0051575 5'-deoxyribose-5-phosphate lyase activity(GO:0051575)
0.3 5.2 GO:0016799 hydrolase activity, hydrolyzing N-glycosyl compounds(GO:0016799)
0.3 3.1 GO:0043522 leucine zipper domain binding(GO:0043522)
0.3 1.8 GO:0008297 single-stranded DNA exodeoxyribonuclease activity(GO:0008297)
0.3 4.8 GO:0008266 poly(U) RNA binding(GO:0008266)
0.2 7.7 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.2 1.2 GO:0030620 U2 snRNA binding(GO:0030620)
0.2 5.7 GO:0070064 proline-rich region binding(GO:0070064)
0.2 1.9 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.2 3.0 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.2 1.4 GO:0001179 RNA polymerase I transcription factor binding(GO:0001179)
0.2 5.0 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.2 1.1 GO:0001226 RNA polymerase II transcription corepressor binding(GO:0001226)
0.2 1.1 GO:0002060 purine nucleobase binding(GO:0002060)
0.2 1.3 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.2 1.3 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.2 0.6 GO:0001042 RNA polymerase I core binding(GO:0001042)
0.2 1.7 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.2 0.8 GO:1990460 leptin receptor binding(GO:1990460)
0.2 8.3 GO:0008536 Ran GTPase binding(GO:0008536)
0.2 0.2 GO:0034046 poly(G) binding(GO:0034046)
0.2 2.2 GO:0070034 telomerase RNA binding(GO:0070034)
0.2 1.0 GO:0004849 uridine kinase activity(GO:0004849)
0.2 6.3 GO:0031369 translation initiation factor binding(GO:0031369)
0.2 0.6 GO:0008532 N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity(GO:0008532)
0.2 1.2 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.2 1.4 GO:0000340 RNA 7-methylguanosine cap binding(GO:0000340)
0.2 0.6 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.2 0.4 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.2 0.6 GO:0004616 phosphogluconate dehydrogenase (decarboxylating) activity(GO:0004616)
0.2 4.1 GO:0003887 DNA-directed DNA polymerase activity(GO:0003887)
0.2 0.6 GO:0004534 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160) 5'-3' exoribonuclease activity(GO:0004534)
0.2 0.6 GO:0003963 RNA-3'-phosphate cyclase activity(GO:0003963)
0.2 1.5 GO:0008026 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004) ATP-dependent helicase activity(GO:0008026) RNA-dependent ATPase activity(GO:0008186) purine NTP-dependent helicase activity(GO:0070035)
0.2 0.4 GO:0033192 calmodulin-dependent protein phosphatase activity(GO:0033192)
0.2 0.5 GO:1990050 phosphatidic acid transporter activity(GO:1990050)
0.2 1.1 GO:0051033 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.2 0.9 GO:0070012 oligopeptidase activity(GO:0070012)
0.2 1.8 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.2 4.9 GO:0015347 sodium-independent organic anion transmembrane transporter activity(GO:0015347)
0.2 1.0 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.2 0.5 GO:0015140 malate transmembrane transporter activity(GO:0015140)
0.2 0.2 GO:0005128 erythropoietin receptor binding(GO:0005128)
0.2 1.4 GO:0031812 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.2 7.3 GO:0003743 translation initiation factor activity(GO:0003743)
0.2 1.1 GO:0016018 cyclosporin A binding(GO:0016018)
0.2 1.0 GO:0005052 peroxisome matrix targeting signal-1 binding(GO:0005052)
0.2 4.3 GO:0016881 acid-amino acid ligase activity(GO:0016881)
0.2 1.3 GO:1901612 cardiolipin binding(GO:1901612)
0.2 0.5 GO:0004487 methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
0.2 0.2 GO:0050816 phosphothreonine binding(GO:0050816)
0.2 0.8 GO:0070883 pre-miRNA binding(GO:0070883)
0.1 4.8 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.1 0.4 GO:0036470 tyrosine 3-monooxygenase activator activity(GO:0036470) L-dopa decarboxylase activator activity(GO:0036478)
0.1 1.0 GO:0005314 high-affinity glutamate transmembrane transporter activity(GO:0005314)
0.1 0.4 GO:0004482 mRNA (guanine-N7-)-methyltransferase activity(GO:0004482)
0.1 0.4 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.1 2.5 GO:0016594 glycine binding(GO:0016594)
0.1 1.2 GO:0001135 transcription factor activity, RNA polymerase II transcription factor recruiting(GO:0001135)
0.1 1.7 GO:0016783 sulfurtransferase activity(GO:0016783)
0.1 5.6 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.1 0.4 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.1 0.4 GO:0005275 amine transmembrane transporter activity(GO:0005275)
0.1 11.6 GO:0003823 antigen binding(GO:0003823)
0.1 3.4 GO:0015215 nucleotide transmembrane transporter activity(GO:0015215)
0.1 0.9 GO:0008467 [heparan sulfate]-glucosamine 3-sulfotransferase 1 activity(GO:0008467)
0.1 3.0 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.1 1.9 GO:0030346 protein phosphatase 2B binding(GO:0030346)
0.1 0.9 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.1 0.9 GO:0005000 vasopressin receptor activity(GO:0005000)
0.1 1.4 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.1 1.1 GO:0034711 inhibin binding(GO:0034711)
0.1 0.8 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1 1.1 GO:0003909 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.1 0.7 GO:0030375 thyroid hormone receptor coactivator activity(GO:0030375)
0.1 9.6 GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups(GO:0016765)
0.1 0.6 GO:0042895 antibiotic transporter activity(GO:0042895)
0.1 0.2 GO:0045182 translation regulator activity(GO:0045182)
0.1 1.1 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.1 4.2 GO:0043021 ribonucleoprotein complex binding(GO:0043021)
0.1 0.9 GO:0030267 hydroxypyruvate reductase activity(GO:0016618) glyoxylate reductase (NADP) activity(GO:0030267)
0.1 1.8 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.1 16.8 GO:0003735 structural constituent of ribosome(GO:0003735)
0.1 1.1 GO:0002161 aminoacyl-tRNA editing activity(GO:0002161)
0.1 0.7 GO:0016624 oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor(GO:0016624)
0.1 1.5 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.1 2.8 GO:0016504 peptidase activator activity(GO:0016504)
0.1 0.9 GO:0005004 GPI-linked ephrin receptor activity(GO:0005004)
0.1 0.7 GO:0051731 polynucleotide 5'-hydroxyl-kinase activity(GO:0051731)
0.1 2.3 GO:0008171 O-methyltransferase activity(GO:0008171)
0.1 1.3 GO:0017154 semaphorin receptor activity(GO:0017154)
0.1 1.2 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.1 0.9 GO:0043208 glycosphingolipid binding(GO:0043208)
0.1 0.6 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.1 3.9 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.1 1.6 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 0.5 GO:0015186 L-glutamine transmembrane transporter activity(GO:0015186)
0.1 4.3 GO:0008307 structural constituent of muscle(GO:0008307)
0.1 0.4 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.1 0.6 GO:0016888 endodeoxyribonuclease activity, producing 5'-phosphomonoesters(GO:0016888)
0.1 0.3 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.1 4.2 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.1 0.3 GO:0004458 D-lactate dehydrogenase (cytochrome) activity(GO:0004458) oxidoreductase activity, acting on the CH-OH group of donors, cytochrome as acceptor(GO:0016898)
0.1 3.5 GO:0051959 dynein light intermediate chain binding(GO:0051959)
0.1 2.9 GO:0008138 protein tyrosine/serine/threonine phosphatase activity(GO:0008138)
0.1 1.3 GO:0008143 poly(A) binding(GO:0008143)
0.1 1.2 GO:0004549 tRNA-specific ribonuclease activity(GO:0004549)
0.1 1.0 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.1 3.8 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.1 2.3 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.1 0.7 GO:0044388 small protein activating enzyme binding(GO:0044388)
0.1 5.5 GO:0005200 structural constituent of cytoskeleton(GO:0005200)
0.1 0.3 GO:0032296 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.1 0.4 GO:0004367 glycerol-3-phosphate dehydrogenase [NAD+] activity(GO:0004367)
0.1 1.9 GO:0008432 JUN kinase binding(GO:0008432)
0.1 0.8 GO:0102337 fatty acid elongase activity(GO:0009922) 3-oxo-arachidoyl-CoA synthase activity(GO:0102336) 3-oxo-cerotoyl-CoA synthase activity(GO:0102337) 3-oxo-lignoceronyl-CoA synthase activity(GO:0102338)
0.1 2.9 GO:0003678 DNA helicase activity(GO:0003678)
0.1 0.3 GO:1902379 chemoattractant activity involved in axon guidance(GO:1902379)
0.1 0.6 GO:0008821 crossover junction endodeoxyribonuclease activity(GO:0008821)
0.1 1.2 GO:0001671 ATPase activator activity(GO:0001671)
0.1 0.9 GO:0003958 NADPH-hemoprotein reductase activity(GO:0003958)
0.1 0.1 GO:0004829 threonine-tRNA ligase activity(GO:0004829)
0.1 1.1 GO:0042043 neurexin family protein binding(GO:0042043)
0.1 0.6 GO:0035198 miRNA binding(GO:0035198)
0.1 0.5 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.1 0.4 GO:0031493 nucleosomal histone binding(GO:0031493)
0.1 3.7 GO:0015485 cholesterol binding(GO:0015485)
0.1 0.9 GO:0003680 AT DNA binding(GO:0003680)
0.1 0.4 GO:0004035 alkaline phosphatase activity(GO:0004035)
0.1 0.1 GO:0071820 N-box binding(GO:0071820)
0.1 0.6 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.1 1.1 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.1 0.5 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.1 1.5 GO:0008094 DNA-dependent ATPase activity(GO:0008094)
0.1 0.4 GO:0008321 Ral guanyl-nucleotide exchange factor activity(GO:0008321)
0.1 0.8 GO:0019531 oxalate transmembrane transporter activity(GO:0019531)
0.1 2.0 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.1 3.4 GO:0008168 methyltransferase activity(GO:0008168)
0.1 0.4 GO:0015220 choline transmembrane transporter activity(GO:0015220)
0.1 2.3 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.1 6.9 GO:0051117 ATPase binding(GO:0051117)
0.1 0.4 GO:0016936 galactosidase activity(GO:0015925) galactoside binding(GO:0016936)
0.1 1.2 GO:0004745 retinol dehydrogenase activity(GO:0004745)
0.1 0.2 GO:0008948 oxaloacetate decarboxylase activity(GO:0008948) hydrolase activity, acting on acid carbon-carbon bonds(GO:0016822) hydrolase activity, acting on acid carbon-carbon bonds, in ketonic substances(GO:0016823)
0.1 0.4 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.1 0.4 GO:0004897 ciliary neurotrophic factor receptor activity(GO:0004897)
0.1 0.3 GO:0016421 CoA carboxylase activity(GO:0016421)
0.1 4.1 GO:0003697 single-stranded DNA binding(GO:0003697)
0.1 1.2 GO:0030506 ankyrin binding(GO:0030506)
0.1 0.5 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.1 0.2 GO:0005483 soluble NSF attachment protein activity(GO:0005483)
0.1 2.8 GO:0005158 insulin receptor binding(GO:0005158)
0.1 0.7 GO:0016863 intramolecular oxidoreductase activity, transposing C=C bonds(GO:0016863)
0.0 1.4 GO:0004386 helicase activity(GO:0004386)
0.0 3.7 GO:0008565 protein transporter activity(GO:0008565)
0.0 1.4 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 3.6 GO:0004843 thiol-dependent ubiquitin-specific protease activity(GO:0004843)
0.0 0.9 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 1.8 GO:0042054 histone methyltransferase activity(GO:0042054)
0.0 0.6 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 0.1 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.0 1.1 GO:0008175 tRNA methyltransferase activity(GO:0008175)
0.0 2.3 GO:0035064 methylated histone binding(GO:0035064)
0.0 0.6 GO:1904264 ubiquitin protein ligase activity involved in ERAD pathway(GO:1904264)
0.0 0.4 GO:0019966 interleukin-1 binding(GO:0019966)
0.0 1.3 GO:0046875 ephrin receptor binding(GO:0046875)
0.0 1.2 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 0.5 GO:0017147 Wnt-protein binding(GO:0017147)
0.0 5.4 GO:0051015 actin filament binding(GO:0051015)
0.0 2.1 GO:0004527 exonuclease activity(GO:0004527)
0.0 1.2 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.3 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 1.5 GO:0016831 carboxy-lyase activity(GO:0016831)
0.0 0.3 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 1.2 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.3 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 11.7 GO:0005096 GTPase activator activity(GO:0005096)
0.0 0.7 GO:0003684 damaged DNA binding(GO:0003684)
0.0 0.6 GO:0004622 lysophospholipase activity(GO:0004622)
0.0 45.0 GO:0003723 RNA binding(GO:0003723)
0.0 0.9 GO:0004864 protein phosphatase inhibitor activity(GO:0004864)
0.0 0.5 GO:0032041 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.0 GO:0070698 type I activin receptor binding(GO:0070698)
0.0 0.1 GO:0008431 vitamin E binding(GO:0008431)
0.0 0.2 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.6 GO:0005326 neurotransmitter transporter activity(GO:0005326)
0.0 0.2 GO:0008294 calcium- and calmodulin-responsive adenylate cyclase activity(GO:0008294)
0.0 0.3 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 1.1 GO:0051082 unfolded protein binding(GO:0051082)
0.0 0.4 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 0.9 GO:0030145 manganese ion binding(GO:0030145)
0.0 0.4 GO:0031418 L-ascorbic acid binding(GO:0031418)
0.0 0.4 GO:0004550 nucleoside diphosphate kinase activity(GO:0004550)
0.0 0.2 GO:0008865 fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0 1.0 GO:0001205 transcriptional activator activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001205)
0.0 0.1 GO:0004692 cGMP-dependent protein kinase activity(GO:0004692)
0.0 0.7 GO:0016709 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen(GO:0016709)
0.0 0.0 GO:0008177 succinate dehydrogenase (ubiquinone) activity(GO:0008177)
0.0 0.7 GO:0019213 deacetylase activity(GO:0019213)
0.0 0.5 GO:0016763 transferase activity, transferring pentosyl groups(GO:0016763)
0.0 0.2 GO:0005212 structural constituent of eye lens(GO:0005212)
0.0 4.7 GO:0045296 cadherin binding(GO:0045296)
0.0 0.2 GO:0048403 brain-derived neurotrophic factor binding(GO:0048403)
0.0 0.5 GO:0051539 4 iron, 4 sulfur cluster binding(GO:0051539)
0.0 0.1 GO:0004985 opioid receptor activity(GO:0004985)
0.0 1.7 GO:0005262 calcium channel activity(GO:0005262)
0.0 0.1 GO:0042979 ornithine decarboxylase regulator activity(GO:0042979)
0.0 0.1 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.3 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.0 0.1 GO:0019828 aspartic-type endopeptidase inhibitor activity(GO:0019828)
0.0 0.1 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.3 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.7 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 2.4 GO:0008022 protein C-terminus binding(GO:0008022)
0.0 0.1 GO:0015234 thiamine transmembrane transporter activity(GO:0015234)
0.0 0.6 GO:0004497 monooxygenase activity(GO:0004497)
0.0 0.1 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.3 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.0 0.2 GO:0051428 peptide hormone receptor binding(GO:0051428)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
1.0 16.5 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.5 9.9 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.3 40.4 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.3 2.1 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.2 1.5 SA G1 AND S PHASES Cdk2, 4, and 6 bind cyclin D in G1, while cdk2/cyclin E promotes the G1/S transition.
0.2 5.8 PID WNT SIGNALING PATHWAY Wnt signaling network
0.2 6.6 PID ATR PATHWAY ATR signaling pathway
0.1 0.4 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.1 0.7 PID AVB3 OPN PATHWAY Osteopontin-mediated events
0.1 2.9 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.1 7.1 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.1 3.6 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.1 5.6 PID MTOR 4PATHWAY mTOR signaling pathway
0.1 7.5 PID NOTCH PATHWAY Notch signaling pathway
0.1 6.1 PID HIF1 TFPATHWAY HIF-1-alpha transcription factor network
0.1 3.2 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.1 4.2 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.1 2.0 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.1 7.0 PID BETA CATENIN NUC PATHWAY Regulation of nuclear beta catenin signaling and target gene transcription
0.1 1.1 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.1 2.1 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.1 1.9 PID ALPHA SYNUCLEIN PATHWAY Alpha-synuclein signaling
0.1 3.2 PID AURORA B PATHWAY Aurora B signaling
0.1 3.4 PID IGF1 PATHWAY IGF1 pathway
0.1 2.2 PID EPHA FWDPATHWAY EPHA forward signaling
0.1 0.9 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.1 2.8 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.1 1.2 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.1 2.4 PID ILK PATHWAY Integrin-linked kinase signaling
0.1 0.8 PID RANBP2 PATHWAY Sumoylation by RanBP2 regulates transcriptional repression
0.1 3.1 PID E2F PATHWAY E2F transcription factor network
0.1 0.2 PID S1P S1P1 PATHWAY S1P1 pathway
0.1 0.9 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.1 1.4 ST GA12 PATHWAY G alpha 12 Pathway
0.1 0.9 PID BARD1 PATHWAY BARD1 signaling events
0.1 2.2 PID RB 1PATHWAY Regulation of retinoblastoma protein
0.1 2.6 PID AR PATHWAY Coregulation of Androgen receptor activity
0.1 0.6 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 2.7 PID TELOMERASE PATHWAY Regulation of Telomerase
0.0 2.8 PID CMYB PATHWAY C-MYB transcription factor network
0.0 1.1 PID RHODOPSIN PATHWAY Visual signal transduction: Rods
0.0 2.6 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 0.2 PID MYC PATHWAY C-MYC pathway
0.0 1.0 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 2.3 PID RHOA REG PATHWAY Regulation of RhoA activity
0.0 1.2 PID INSULIN PATHWAY Insulin Pathway
0.0 0.4 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway
0.0 0.9 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 0.4 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.9 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events
0.0 0.1 PID TXA2PATHWAY Thromboxane A2 receptor signaling
0.0 0.3 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.2 PID LPA4 PATHWAY LPA4-mediated signaling events
0.0 0.3 ST JNK MAPK PATHWAY JNK MAPK Pathway
0.0 0.2 NABA COLLAGENS Genes encoding collagen proteins
0.0 0.3 PID PI3KCI PATHWAY Class I PI3K signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
2.7 2.7 REACTOME NRAGE SIGNALS DEATH THROUGH JNK Genes involved in NRAGE signals death through JNK
1.3 13.8 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.6 9.4 REACTOME PROCESSIVE SYNTHESIS ON THE LAGGING STRAND Genes involved in Processive synthesis on the lagging strand
0.6 10.6 REACTOME PHOSPHORYLATION OF THE APC C Genes involved in Phosphorylation of the APC/C
0.5 7.7 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.5 32.5 REACTOME ACTIVATION OF THE MRNA UPON BINDING OF THE CAP BINDING COMPLEX AND EIFS AND SUBSEQUENT BINDING TO 43S Genes involved in Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S
0.5 10.4 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.4 5.7 REACTOME REGULATION OF PYRUVATE DEHYDROGENASE PDH COMPLEX Genes involved in Regulation of pyruvate dehydrogenase (PDH) complex
0.4 3.5 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.4 6.3 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.4 13.8 REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery
0.4 3.7 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.4 2.9 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.4 9.9 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.3 2.7 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.3 4.3 REACTOME RESOLUTION OF AP SITES VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Resolution of AP sites via the single-nucleotide replacement pathway
0.3 12.3 REACTOME G1 PHASE Genes involved in G1 Phase
0.3 15.8 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.3 10.3 REACTOME ASSOCIATION OF TRIC CCT WITH TARGET PROTEINS DURING BIOSYNTHESIS Genes involved in Association of TriC/CCT with target proteins during biosynthesis
0.3 5.7 REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS Genes involved in Activation of ATR in response to replication stress
0.3 6.5 REACTOME G0 AND EARLY G1 Genes involved in G0 and Early G1
0.3 2.9 REACTOME HIGHLY CALCIUM PERMEABLE POSTSYNAPTIC NICOTINIC ACETYLCHOLINE RECEPTORS Genes involved in Highly calcium permeable postsynaptic nicotinic acetylcholine receptors
0.3 10.1 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.2 4.4 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.2 16.2 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.2 3.8 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.2 0.4 REACTOME MRNA CAPPING Genes involved in mRNA Capping
0.2 2.5 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.2 7.3 REACTOME ACTIVATED NOTCH1 TRANSMITS SIGNAL TO THE NUCLEUS Genes involved in Activated NOTCH1 Transmits Signal to the Nucleus
0.2 5.0 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.2 4.0 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.2 1.2 REACTOME NRIF SIGNALS CELL DEATH FROM THE NUCLEUS Genes involved in NRIF signals cell death from the nucleus
0.2 2.6 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.2 3.3 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening
0.2 3.4 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.1 3.0 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.1 1.1 REACTOME GLYCOPROTEIN HORMONES Genes involved in Glycoprotein hormones
0.1 3.1 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.1 3.5 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.1 3.1 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.1 2.6 REACTOME INFLUENZA VIRAL RNA TRANSCRIPTION AND REPLICATION Genes involved in Influenza Viral RNA Transcription and Replication
0.1 4.8 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.1 2.9 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.1 3.2 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1 5.7 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.1 5.1 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.1 3.9 REACTOME FATTY ACYL COA BIOSYNTHESIS Genes involved in Fatty Acyl-CoA Biosynthesis
0.1 1.0 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.1 0.3 REACTOME CELL DEATH SIGNALLING VIA NRAGE NRIF AND NADE Genes involved in Cell death signalling via NRAGE, NRIF and NADE
0.1 1.7 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.1 1.1 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.1 4.6 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.1 1.9 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.1 1.3 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.1 1.8 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.1 1.3 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.1 0.5 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.1 4.8 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.1 3.8 REACTOME METABOLISM OF VITAMINS AND COFACTORS Genes involved in Metabolism of vitamins and cofactors
0.1 1.8 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.1 2.0 REACTOME ABC FAMILY PROTEINS MEDIATED TRANSPORT Genes involved in ABC-family proteins mediated transport
0.1 1.3 REACTOME LATE PHASE OF HIV LIFE CYCLE Genes involved in Late Phase of HIV Life Cycle
0.1 0.7 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.1 0.8 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 1.8 REACTOME TRIGLYCERIDE BIOSYNTHESIS Genes involved in Triglyceride Biosynthesis
0.0 4.4 REACTOME MRNA SPLICING Genes involved in mRNA Splicing
0.0 0.9 REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION Genes involved in GABA synthesis, release, reuptake and degradation
0.0 1.0 REACTOME PRE NOTCH PROCESSING IN GOLGI Genes involved in Pre-NOTCH Processing in Golgi
0.0 0.9 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling
0.0 1.2 REACTOME SIGNALING BY HIPPO Genes involved in Signaling by Hippo
0.0 1.3 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 0.4 REACTOME AMINE COMPOUND SLC TRANSPORTERS Genes involved in Amine compound SLC transporters
0.0 0.6 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 2.6 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 1.5 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.8 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.8 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits
0.0 0.3 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 1.3 REACTOME INTERACTION BETWEEN L1 AND ANKYRINS Genes involved in Interaction between L1 and Ankyrins
0.0 1.5 REACTOME VIF MEDIATED DEGRADATION OF APOBEC3G Genes involved in Vif-mediated degradation of APOBEC3G
0.0 0.2 REACTOME MICRORNA MIRNA BIOGENESIS Genes involved in MicroRNA (miRNA) Biogenesis
0.0 0.4 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway
0.0 0.1 REACTOME RNA POL I TRANSCRIPTION INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.0 0.2 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 1.9 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.3 REACTOME ACTIVATION OF RAC Genes involved in Activation of Rac
0.0 0.0 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.0 0.3 REACTOME FORMATION OF FIBRIN CLOT CLOTTING CASCADE Genes involved in Formation of Fibrin Clot (Clotting Cascade)
0.0 0.2 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 1.4 REACTOME DNA REPAIR Genes involved in DNA Repair
0.0 0.2 REACTOME REGULATION OF APOPTOSIS Genes involved in Regulation of Apoptosis
0.0 0.4 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.2 REACTOME REGULATION OF WATER BALANCE BY RENAL AQUAPORINS Genes involved in Regulation of Water Balance by Renal Aquaporins
0.0 1.0 REACTOME TRANSLATION Genes involved in Translation
0.0 0.4 REACTOME REGULATION OF AMPK ACTIVITY VIA LKB1 Genes involved in Regulation of AMPK activity via LKB1
0.0 1.5 REACTOME METABOLISM OF AMINO ACIDS AND DERIVATIVES Genes involved in Metabolism of amino acids and derivatives
0.0 3.2 REACTOME ANTIGEN PROCESSING UBIQUITINATION PROTEASOME DEGRADATION Genes involved in Antigen processing: Ubiquitination & Proteasome degradation
0.0 0.3 REACTOME ACYL CHAIN REMODELLING OF PI Genes involved in Acyl chain remodelling of PI
0.0 2.2 REACTOME G ALPHA I SIGNALLING EVENTS Genes involved in G alpha (i) signalling events
0.0 0.5 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction
0.0 0.2 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 1.2 REACTOME NUCLEAR RECEPTOR TRANSCRIPTION PATHWAY Genes involved in Nuclear Receptor transcription pathway
0.0 0.2 REACTOME KERATAN SULFATE BIOSYNTHESIS Genes involved in Keratan sulfate biosynthesis
0.0 0.6 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 1.2 REACTOME FACTORS INVOLVED IN MEGAKARYOCYTE DEVELOPMENT AND PLATELET PRODUCTION Genes involved in Factors involved in megakaryocyte development and platelet production