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2D miR_HR1_12

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Results for Nkx3-1

Z-value: 0.90

Motif logo

Transcription factors associated with Nkx3-1

Gene Symbol Gene ID Gene Info
ENSMUSG00000022061.8 NK3 homeobox 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Nkx3-1mm10_v2_chr14_+_69190638_69190691-0.728.3e-03Click!

Activity profile of Nkx3-1 motif

Sorted Z-values of Nkx3-1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chrX_+_164438039 2.41 ENSMUST00000033755.5
ankyrin repeat and SOCS box-containing 11
chr19_+_58759700 2.29 ENSMUST00000026081.3
pancreatic lipase-related protein 2
chr1_+_171155512 1.78 ENSMUST00000111334.1
myelin protein zero
chr4_-_137409777 1.57 ENSMUST00000024200.6
predicted gene 13011
chr4_-_137430517 1.44 ENSMUST00000102522.4
chymotrypsin-like elastase family, member 3B
chr6_+_78425973 1.39 ENSMUST00000079926.5
regenerating islet-derived 1
chr3_-_113324052 1.21 ENSMUST00000179314.1
amylase 2a3
chr10_+_5639210 1.16 ENSMUST00000019906.4
vasoactive intestinal polypeptide
chr6_-_41035501 1.16 ENSMUST00000031931.5
RIKEN cDNA 2210010C04 gene
chr1_-_162478004 1.13 ENSMUST00000086074.5
ENSMUST00000070330.7
dynamin 3
chr19_+_5406815 1.13 ENSMUST00000174412.1
ENSMUST00000153017.2
RIKEN cDNA 4930481A15 gene
chr3_-_113291449 1.02 ENSMUST00000179568.1
amylase 2a4
chr8_+_114133557 1.02 ENSMUST00000073521.5
ENSMUST00000066514.6
nudix (nucleoside diphosphate linked moiety X)-type motif 7
chr4_+_104766308 1.01 ENSMUST00000031663.3
complement component 8, beta polypeptide
chr16_+_32756336 0.97 ENSMUST00000135753.1
mucin 4
chr8_+_114133601 0.97 ENSMUST00000109109.1
nudix (nucleoside diphosphate linked moiety X)-type motif 7
chr4_+_110397661 0.97 ENSMUST00000106589.2
ENSMUST00000106587.2
ENSMUST00000106591.1
ENSMUST00000106592.1
ATP/GTP binding protein-like 4
chr13_-_99900645 0.95 ENSMUST00000022150.6
CART prepropeptide
chr9_-_62537036 0.93 ENSMUST00000048043.5
coronin, actin binding protein, 2B
chr3_-_113356658 0.90 ENSMUST00000098667.3
amylase 2a2
chr5_+_90367204 0.89 ENSMUST00000068250.3
predicted gene 9958
chr4_+_110397764 0.89 ENSMUST00000097920.2
ENSMUST00000080744.6
ATP/GTP binding protein-like 4
chr8_+_114133635 0.88 ENSMUST00000147605.1
ENSMUST00000134593.1
nudix (nucleoside diphosphate linked moiety X)-type motif 7
chr3_-_113532288 0.87 ENSMUST00000132353.1
amylase 2a1
chr3_-_113258837 0.87 ENSMUST00000098673.3
amylase 2a5
chr18_-_6241486 0.85 ENSMUST00000025083.7
kinesin family member 5B
chr14_+_41131777 0.85 ENSMUST00000022314.3
ENSMUST00000170719.1
surfactant associated protein A1
chr10_-_41579207 0.85 ENSMUST00000095227.3
coiled-coil domain containing 162
chr4_-_108217897 0.80 ENSMUST00000106690.1
ENSMUST00000043793.6
zyg-11 family member A, cell cycle regulator
chr5_+_66968416 0.78 ENSMUST00000038188.7
LIM and calponin homology domains 1
chr1_-_174921813 0.78 ENSMUST00000055294.3
gremlin 2 homolog, cysteine knot superfamily (Xenopus laevis)
chr9_+_99470440 0.76 ENSMUST00000056103.4
RIKEN cDNA 1600029I14 gene
chr12_-_78983476 0.75 ENSMUST00000070174.7
transmembrane protein 229B
chr8_+_71689214 0.71 ENSMUST00000034261.7
insulin-like 3
chr1_+_171503410 0.68 ENSMUST00000081527.1
Aly/REF export factor 2
chr1_-_162866502 0.65 ENSMUST00000046049.7
flavin containing monooxygenase 1
chr9_+_78191966 0.65 ENSMUST00000034903.5
glutathione S-transferase, alpha 4
chr10_-_115185015 0.64 ENSMUST00000006949.8
tryptophan hydroxylase 2
chr7_+_12834743 0.64 ENSMUST00000004614.8
zinc finger protein 110
chr4_-_45530330 0.62 ENSMUST00000061986.5
src homology 2 domain-containing transforming protein B
chr17_-_78418083 0.62 ENSMUST00000070039.7
ENSMUST00000112487.1
fasciculation and elongation protein zeta 2 (zygin II)
chr2_+_84734050 0.62 ENSMUST00000090729.2
yippee-like 4 (Drosophila)
chr7_+_110627650 0.61 ENSMUST00000033054.8
adrenomedullin
chr11_-_58613481 0.60 ENSMUST00000048801.7
RIKEN cDNA 2210407C18 gene
chr15_-_75111684 0.58 ENSMUST00000100542.3
lymphocyte antigen 6 complex, locus C2
chr15_-_75048837 0.57 ENSMUST00000179762.1
ENSMUST00000065408.9
lymphocyte antigen 6 complex, locus C1
chr17_+_37270214 0.56 ENSMUST00000038580.6
histocompatibility 2, M region locus 3
chr10_+_69219357 0.53 ENSMUST00000172261.1
Rho-related BTB domain containing 1
chr7_-_127930066 0.50 ENSMUST00000032988.8
protease, serine, 8 (prostasin)
chr14_-_73049107 0.50 ENSMUST00000044664.4
ENSMUST00000169168.1
cysteinyl leukotriene receptor 2
chrX_+_163911401 0.47 ENSMUST00000140845.1
adaptor-related protein complex 1, sigma 2 subunit
chr3_-_88027465 0.47 ENSMUST00000005014.2
hyaluronan and proteoglycan link protein 2
chr9_+_108049254 0.47 ENSMUST00000112295.2
ENSMUST00000047947.7
GDP-mannose pyrophosphorylase B
chr19_+_20601958 0.46 ENSMUST00000087638.3
aldehyde dehydrogenase family 1, subfamily A1
chr15_-_74997634 0.45 ENSMUST00000023248.6
lymphocyte antigen 6 complex, locus A
chr11_+_69098937 0.44 ENSMUST00000021271.7
period circadian clock 1
chr9_-_20976762 0.44 ENSMUST00000054197.5
sphingosine-1-phosphate receptor 2
chr2_-_84715160 0.43 ENSMUST00000035840.5
zinc finger, DHHC domain containing 5
chr9_-_122310921 0.42 ENSMUST00000180685.1
predicted gene, 26797
chr18_-_6241470 0.42 ENSMUST00000163210.1
kinesin family member 5B
chr7_-_25237849 0.42 ENSMUST00000071739.5
ENSMUST00000108411.1
glycogen synthase kinase 3 alpha
chr3_-_104818539 0.41 ENSMUST00000106774.1
ENSMUST00000106775.1
ENSMUST00000166979.1
ENSMUST00000136148.1
Moloney leukemia virus 10
chr2_+_23068168 0.40 ENSMUST00000028121.7
ENSMUST00000114523.2
ENSMUST00000144088.1
acyl-Coenzyme A binding domain containing 5
chrX_+_56454871 0.39 ENSMUST00000039374.2
ENSMUST00000101553.2
DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 26B
chr19_-_17356631 0.38 ENSMUST00000174236.1
glucosaminyl (N-acetyl) transferase 1, core 2
chrX_-_101222426 0.38 ENSMUST00000120389.1
ENSMUST00000156473.1
ENSMUST00000077876.3
sorting nexin 12
chr18_+_75018709 0.38 ENSMUST00000039608.7
dymeclin
chr16_-_48771956 0.37 ENSMUST00000170861.1
T cell receptor associated transmembrane adaptor 1
chr7_+_58658181 0.37 ENSMUST00000168747.1
ATPase, class V, type 10A
chrX_+_7919816 0.37 ENSMUST00000041096.3
proprotein convertase subtilisin/kexin type 1 inhibitor
chr17_-_47692466 0.34 ENSMUST00000113300.1
prickle homolog 4 (Drosophila)
chr5_+_8422831 0.34 ENSMUST00000066921.3
solute carrier family 25, member 40
chr1_-_156034800 0.34 ENSMUST00000169241.1
torsin A interacting protein 1
chr11_-_103697661 0.34 ENSMUST00000107013.2
golgi SNAP receptor complex member 2
chr8_+_36457548 0.33 ENSMUST00000135373.1
ENSMUST00000147525.1
RIKEN cDNA 6430573F11 gene
chr4_-_103026709 0.33 ENSMUST00000084382.5
ENSMUST00000106869.2
insulin-like 5
chr7_+_139214661 0.32 ENSMUST00000135509.1
leucine rich repeat containing 27
chr14_-_54864055 0.31 ENSMUST00000142283.2
homeodomain leucine zipper-encoding gene
chr10_-_59441748 0.30 ENSMUST00000009798.4
oncoprotein induced transcript 3
chr15_+_100422147 0.30 ENSMUST00000132119.1
predicted gene 5475
chr10_-_12861735 0.29 ENSMUST00000076817.4
utrophin
chr8_-_69791170 0.29 ENSMUST00000131784.1
zinc finger protein 866
chr7_-_121035096 0.29 ENSMUST00000065740.2
predicted gene 9905
chr4_+_3940747 0.29 ENSMUST00000119403.1
coiled-coil-helix-coiled-coil-helix domain containing 7
chrX_-_8206475 0.28 ENSMUST00000089403.3
ENSMUST00000077595.5
ENSMUST00000089402.3
ENSMUST00000082320.5
porcupine homolog (Drosophila)
chr12_-_87233556 0.27 ENSMUST00000021423.7
NADP+ dependent oxidoreductase domain containing 1
chr17_-_36190121 0.26 ENSMUST00000097329.3
ENSMUST00000025312.6
ENSMUST00000102675.3
histocompatibility 2, T region locus 3
chr3_-_57575907 0.26 ENSMUST00000120977.1
WW domain containing transcription regulator 1
chr4_+_134397380 0.26 ENSMUST00000105870.1
platelet-activating factor acetylhydrolase 2
chr2_+_25403128 0.26 ENSMUST00000154809.1
ENSMUST00000055921.7
ENSMUST00000141567.1
neural proliferation, differentiation and control 1
chr4_-_99654983 0.25 ENSMUST00000136525.1
predicted gene 12688
chr17_+_84956718 0.25 ENSMUST00000112305.3
protein phosphatase 1B, magnesium dependent, beta isoform
chr11_-_101278927 0.25 ENSMUST00000168089.1
ENSMUST00000017332.3
cytochrome C oxidase assembly factor 3
chr4_+_62619515 0.24 ENSMUST00000084521.4
ENSMUST00000107424.1
regulator of G-protein signaling 3
chr7_+_123123870 0.24 ENSMUST00000094053.5
trinucleotide repeat containing 6a
chr16_+_87553313 0.24 ENSMUST00000026700.7
Map3k7 C-terminal like
chr17_+_29268788 0.24 ENSMUST00000064709.5
ENSMUST00000120346.1
cDNA sequence BC004004
chr2_+_25403044 0.24 ENSMUST00000071442.5
neural proliferation, differentiation and control 1
chr15_-_74983430 0.24 ENSMUST00000023250.4
ENSMUST00000166694.1
lymphocyte antigen 6 complex, locus I
chr14_-_43923368 0.22 ENSMUST00000163652.1
eosinophil-associated, ribonuclease A family, member 10
chr11_+_101279092 0.22 ENSMUST00000103107.4
cyclin N-terminal domain containing 1
chr3_-_30140407 0.22 ENSMUST00000108271.3
MDS1 and EVI1 complex locus
chr17_+_35135196 0.21 ENSMUST00000172571.1
ENSMUST00000173491.1
BCL2-associated athanogene 6
chr3_+_30792876 0.21 ENSMUST00000029256.7
SEC62 homolog (S. cerevisiae)
chr7_+_75455534 0.21 ENSMUST00000147005.1
ENSMUST00000166315.1
A kinase (PRKA) anchor protein 13
chr17_+_35135174 0.21 ENSMUST00000166426.2
ENSMUST00000025250.7
BCL2-associated athanogene 6
chr19_+_43689672 0.20 ENSMUST00000081079.5
ectonucleoside triphosphate diphosphohydrolase 7
chr12_+_59095653 0.19 ENSMUST00000021384.4
melanoma inhibitory activity 2
chr15_+_75268379 0.18 ENSMUST00000023247.6
lymphocyte antigen 6 complex, locus F
chr9_+_89199209 0.18 ENSMUST00000068569.4
B cell leukemia/lymphoma 2 related protein A1b
chr2_-_93849679 0.18 ENSMUST00000068513.4
ENSMUST00000041593.8
ENSMUST00000130077.1
1-aminocyclopropane-1-carboxylate synthase (non-functional)
chr9_+_89199319 0.18 ENSMUST00000138109.1
5, 10-methenyltetrahydrofolate synthetase
chr5_-_145879857 0.17 ENSMUST00000035918.7
cytochrome P450, family 3, subfamily a, polypeptide 11
chr8_+_47824459 0.17 ENSMUST00000038693.6
claudin 22
chr1_+_167598450 0.17 ENSMUST00000111386.1
ENSMUST00000111384.1
retinoid X receptor gamma
chr11_-_21370452 0.16 ENSMUST00000102875.4
UDP-glucose pyrophosphorylase 2
chr5_-_38491948 0.15 ENSMUST00000129099.1
solute carrier family 2 (facilitated glucose transporter), member 9
chr5_-_21424664 0.15 ENSMUST00000115245.1
ENSMUST00000030552.5
coiled-coil domain containing 146
chr12_-_103694657 0.15 ENSMUST00000117053.1
serine (or cysteine) peptidase inhibitor, clade A, member 1F
chr5_-_72559599 0.14 ENSMUST00000074948.4
ENSMUST00000087216.5
nuclear transcription factor, X-box binding-like 1
chr18_+_60963517 0.14 ENSMUST00000115295.2
ENSMUST00000039904.6
calcium/calmodulin-dependent protein kinase II alpha
chr13_+_23571382 0.14 ENSMUST00000079251.5
histone cluster 1, H2bg
chr19_+_8819401 0.14 ENSMUST00000096753.3
heterogeneous nuclear ribonucleoprotein U-like 2
chr8_-_95807458 0.14 ENSMUST00000098473.4
ENSMUST00000068452.8
CCR4-NOT transcription complex, subunit 1
chr17_-_79715034 0.14 ENSMUST00000024894.1
cytochrome P450, family 1, subfamily b, polypeptide 1
chr3_-_57575760 0.14 ENSMUST00000029380.7
WW domain containing transcription regulator 1
chr10_+_4432467 0.13 ENSMUST00000095893.4
ENSMUST00000118544.1
ENSMUST00000117489.1
RIKEN cDNA 1700052N19 gene
chr4_-_121017201 0.13 ENSMUST00000043200.7
small ArfGAP 2
chr12_+_8012359 0.13 ENSMUST00000171239.1
apolipoprotein B
chr5_+_28071356 0.13 ENSMUST00000059155.10
insulin induced gene 1
chrX_-_75874536 0.13 ENSMUST00000033547.7
plastin 3 (T-isoform)
chr8_-_3748941 0.13 ENSMUST00000012847.1
CD209a antigen
chrX_+_14211148 0.11 ENSMUST00000079952.2
predicted gene 5382
chr16_+_20535475 0.11 ENSMUST00000090023.6
ENSMUST00000007216.8
adaptor-related protein complex 2, mu 1 subunit
chr13_+_51408618 0.11 ENSMUST00000087978.3
sphingosine-1-phosphate receptor 3
chr10_+_90576872 0.11 ENSMUST00000182550.1
ENSMUST00000099364.5
ankyrin repeat and sterile alpha motif domain containing 1B
chr17_-_38131190 0.11 ENSMUST00000087128.1
olfactory receptor 132
chr7_+_5350542 0.10 ENSMUST00000056639.6
predicted gene 5065
chr14_-_46831984 0.10 ENSMUST00000181311.1
ENSMUST00000074862.2
predicted gene 10101
chr8_-_41041828 0.10 ENSMUST00000051379.7
mitochondrial tumor suppressor 1
chr19_-_8405060 0.10 ENSMUST00000064507.5
ENSMUST00000120540.1
ENSMUST00000096269.4
solute carrier family 22, member 30
chr6_+_58833689 0.09 ENSMUST00000041401.8
hect domain and RLD 3
chr3_-_20242173 0.09 ENSMUST00000001921.1
carboxypeptidase A3, mast cell
chr10_-_14718191 0.09 ENSMUST00000020016.4
gap junction protein, epsilon 1
chr9_-_103222063 0.09 ENSMUST00000170904.1
transferrin
chr14_-_21748610 0.08 ENSMUST00000075040.2
ENSMUST00000183943.1
dual specificity phosphatase 13
chrX_+_134187492 0.08 ENSMUST00000064476.4
ADP-ribosylation factor-like 13A
chr2_+_79707780 0.08 ENSMUST00000090760.2
ENSMUST00000040863.4
ENSMUST00000111780.2
protein phosphatase 1, regulatory (inhibitor) subunit 1C
chr10_-_13324160 0.08 ENSMUST00000105545.4
phosphatase and actin regulator 2
chrX_-_100625901 0.08 ENSMUST00000059099.6
PDZ domain containing 11
chr1_+_167598384 0.08 ENSMUST00000015987.3
retinoid X receptor gamma
chr1_-_133907053 0.08 ENSMUST00000149380.1
ENSMUST00000124051.2
opticin
chr8_+_69791163 0.08 ENSMUST00000034326.6
ATPase type 13A1
chr10_+_90576777 0.08 ENSMUST00000183136.1
ENSMUST00000182595.1
ankyrin repeat and sterile alpha motif domain containing 1B
chr10_+_90576708 0.07 ENSMUST00000182430.1
ENSMUST00000182960.1
ENSMUST00000182045.1
ENSMUST00000182083.1
ankyrin repeat and sterile alpha motif domain containing 1B
chr14_+_61309753 0.07 ENSMUST00000055159.7
ADP-ribosylation factor-like 11
chr4_-_140774196 0.07 ENSMUST00000026381.6
peptidyl arginine deiminase, type IV
chr10_+_102159000 0.07 ENSMUST00000020039.6
mannosyl (alpha-1,3-)-glycoprotein beta-1,4-N-acetylglucosaminyltransferase, isozyme C (putative)
chr2_-_84775388 0.07 ENSMUST00000023994.3
serine (or cysteine) peptidase inhibitor, clade G, member 1
chr1_-_133906973 0.07 ENSMUST00000126123.1
opticin
chr2_-_84775420 0.06 ENSMUST00000111641.1
serine (or cysteine) peptidase inhibitor, clade G, member 1
chr15_+_78597047 0.06 ENSMUST00000043069.5
cytohesin 4
chr2_+_132846638 0.06 ENSMUST00000028835.6
ENSMUST00000110122.3
cardiolipin synthase 1
chr10_-_128211788 0.06 ENSMUST00000061995.8
SPRY domain containing 4
chr2_+_57997884 0.05 ENSMUST00000112616.1
ENSMUST00000166729.1
UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase 5
chr14_-_55788810 0.05 ENSMUST00000022830.6
ENSMUST00000168716.1
ENSMUST00000178399.1
receptor-interacting serine-threonine kinase 3
chr6_-_83527986 0.05 ENSMUST00000121731.1
actin, gamma 2, smooth muscle, enteric
chr9_+_58079310 0.04 ENSMUST00000136154.1
stimulated by retinoic acid gene 6
chr10_+_90576252 0.04 ENSMUST00000182427.1
ENSMUST00000182053.1
ENSMUST00000182113.1
ankyrin repeat and sterile alpha motif domain containing 1B
chr5_-_69592274 0.04 ENSMUST00000174233.1
ENSMUST00000120789.1
ENSMUST00000166298.1
glucosamine-6-phosphate deaminase 2
chr12_+_17266545 0.04 ENSMUST00000057288.5
protein disulfide isomerase associated 6
chr10_+_90576570 0.04 ENSMUST00000182786.1
ENSMUST00000182600.1
ankyrin repeat and sterile alpha motif domain containing 1B
chr1_-_173766876 0.04 ENSMUST00000111214.2
interferon activated gene 204
chr7_-_126922887 0.03 ENSMUST00000134134.1
ENSMUST00000119781.1
ENSMUST00000121612.2
transmembrane protein 219
chr1_-_52953179 0.03 ENSMUST00000114492.1
RIKEN cDNA 1700019D03 gene
chr12_+_52516077 0.03 ENSMUST00000110725.1
Rho GTPase activating protein 5
chr9_-_18512885 0.03 ENSMUST00000034653.6
mucin 16
chr5_+_107597760 0.03 ENSMUST00000112655.1
RNA polymerase II associated protein 2
chr12_-_100159601 0.03 ENSMUST00000021596.7
nrde-2 necessary for RNA interference, domain containing
chr10_+_90576678 0.03 ENSMUST00000182284.1
ankyrin repeat and sterile alpha motif domain containing 1B
chr12_-_54695829 0.02 ENSMUST00000162106.1
ENSMUST00000160085.1
ENSMUST00000161592.1
ENSMUST00000163433.1
E2F-associated phosphoprotein
chr6_+_18170782 0.02 ENSMUST00000115406.1
cystic fibrosis transmembrane conductance regulator
chr1_-_130452416 0.02 ENSMUST00000140400.1
CD55 antigen
chrX_+_150547375 0.02 ENSMUST00000066337.6
ENSMUST00000112715.1
aminolevulinic acid synthase 2, erythroid
chr3_-_64137480 0.02 ENSMUST00000077958.3
vomeronasal 2, receptor 2
chr3_-_102782708 0.02 ENSMUST00000029450.3
ENSMUST00000172026.1
ENSMUST00000170856.1
thyroid stimulating hormone, beta subunit
chr7_+_102702331 0.02 ENSMUST00000094124.3
olfactory receptor 558
chr5_+_142629537 0.02 ENSMUST00000036872.9
ENSMUST00000110778.1
WD repeat domain, phosphoinositide interacting 2
chr12_-_52028063 0.01 ENSMUST00000040161.4
G protein-coupled receptor 33
chr4_-_115496129 0.01 ENSMUST00000030487.2
cytochrome P450, family 4, subfamily a, polypeptide 14
chrX_-_75875101 0.01 ENSMUST00000114059.3
plastin 3 (T-isoform)
chr10_-_60752773 0.01 ENSMUST00000117513.1
ENSMUST00000119595.1
solute carrier family 29 (nucleoside transporters), member 3
chr7_+_43607169 0.01 ENSMUST00000120935.1
ENSMUST00000127765.1
ENSMUST00000032661.7
zinc finger protein 819
chr18_+_82910863 0.00 ENSMUST00000171238.1
zinc finger protein 516
chr13_+_33084113 0.00 ENSMUST00000016951.7
serine (or cysteine) peptidase inhibitor, clade B, member 1b
chr4_-_15149755 0.00 ENSMUST00000108273.1
N-terminal EF-hand calcium binding protein 1

Network of associatons between targets according to the STRING database.

First level regulatory network of Nkx3-1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.9 GO:0046356 coenzyme A catabolic process(GO:0015938) nucleoside bisphosphate catabolic process(GO:0033869) ribonucleoside bisphosphate catabolic process(GO:0034031) purine nucleoside bisphosphate catabolic process(GO:0034034) acetyl-CoA catabolic process(GO:0046356)
0.5 1.9 GO:0035609 C-terminal protein deglutamylation(GO:0035609)
0.3 1.0 GO:0070093 negative regulation of glucagon secretion(GO:0070093)
0.3 1.1 GO:0098884 postsynaptic neurotransmitter receptor internalization(GO:0098884)
0.3 0.8 GO:0060300 regulation of cytokine activity(GO:0060300)
0.3 1.3 GO:0072383 stress granule disassembly(GO:0035617) plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386) regulation of voltage-gated sodium channel activity(GO:1905150)
0.2 1.2 GO:0010578 regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010578) positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway(GO:0010579)
0.2 1.0 GO:0002835 negative regulation of response to tumor cell(GO:0002835) negative regulation of immune response to tumor cell(GO:0002838)
0.1 2.3 GO:0006968 cellular defense response(GO:0006968) glycolipid catabolic process(GO:0019377)
0.1 0.6 GO:0002477 antigen processing and presentation of exogenous peptide antigen via MHC class Ib(GO:0002477) antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent(GO:0002481) immune response-inhibiting cell surface receptor signaling pathway(GO:0002767)
0.1 1.8 GO:0045217 cell-cell junction maintenance(GO:0045217)
0.1 0.4 GO:2000642 negative regulation of early endosome to late endosome transport(GO:2000642)
0.1 0.4 GO:0036015 response to interleukin-3(GO:0036015) cellular response to interleukin-3(GO:0036016)
0.1 0.4 GO:0098795 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.1 1.4 GO:0061469 regulation of type B pancreatic cell proliferation(GO:0061469)
0.1 0.5 GO:0008065 establishment of blood-nerve barrier(GO:0008065)
0.1 0.8 GO:0008228 opsonization(GO:0008228)
0.1 0.6 GO:1990009 retinal cell apoptotic process(GO:1990009)
0.1 0.4 GO:0097167 circadian regulation of translation(GO:0097167)
0.1 1.0 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.1 0.6 GO:0097647 calcitonin family receptor signaling pathway(GO:0097646) amylin receptor signaling pathway(GO:0097647)
0.1 0.4 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.1 0.3 GO:0007525 somatic muscle development(GO:0007525)
0.1 0.6 GO:1901162 serotonin biosynthetic process(GO:0042427) primary amino compound biosynthetic process(GO:1901162)
0.1 0.1 GO:0018894 dibenzo-p-dioxin metabolic process(GO:0018894)
0.1 0.5 GO:0042904 9-cis-retinoic acid biosynthetic process(GO:0042904) 9-cis-retinoic acid metabolic process(GO:0042905)
0.1 0.4 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376) positive regulation of endothelial cell development(GO:1901552) positive regulation of establishment of endothelial barrier(GO:1903142)
0.1 0.6 GO:1900194 negative regulation of oocyte maturation(GO:1900194)
0.1 0.4 GO:0072257 metanephric nephron tubule epithelial cell differentiation(GO:0072257) regulation of metanephric nephron tubule epithelial cell differentiation(GO:0072307)
0.1 0.4 GO:0030242 pexophagy(GO:0030242)
0.1 0.2 GO:0019255 UDP-glucose metabolic process(GO:0006011) glucose 1-phosphate metabolic process(GO:0019255)
0.1 0.4 GO:0036506 maintenance of unfolded protein(GO:0036506) tail-anchored membrane protein insertion into ER membrane(GO:0071816) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.0 0.6 GO:0070995 NADPH oxidation(GO:0070995)
0.0 0.7 GO:2000018 regulation of male gonad development(GO:2000018)
0.0 0.6 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.0 0.1 GO:0001869 regulation of complement activation, lectin pathway(GO:0001868) negative regulation of complement activation, lectin pathway(GO:0001869)
0.0 0.3 GO:0006499 N-terminal protein myristoylation(GO:0006499)
0.0 0.3 GO:2000253 positive regulation of feeding behavior(GO:2000253)
0.0 0.3 GO:0006561 proline biosynthetic process(GO:0006561)
0.0 0.3 GO:0071763 nuclear membrane organization(GO:0071763)
0.0 0.5 GO:0070633 transepithelial transport(GO:0070633)
0.0 0.2 GO:1901727 positive regulation of histone deacetylase activity(GO:1901727)
0.0 0.1 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.0 0.3 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.0 0.4 GO:1900383 regulation of synaptic plasticity by receptor localization to synapse(GO:1900383)
0.0 0.3 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 0.4 GO:0060352 cell adhesion molecule production(GO:0060352)
0.0 0.2 GO:0071883 activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.0 0.0 GO:2000449 regulation of CD8-positive, alpha-beta T cell extravasation(GO:2000449)
0.0 0.1 GO:0018101 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.0 0.2 GO:0009396 folic acid-containing compound biosynthetic process(GO:0009396)
0.0 0.2 GO:0035278 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0 0.1 GO:0016185 synaptic vesicle budding from presynaptic endocytic zone membrane(GO:0016185)
0.0 0.1 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.0 0.1 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0 0.2 GO:0009191 ribonucleoside diphosphate catabolic process(GO:0009191)
0.0 0.1 GO:0070447 positive regulation of oligodendrocyte progenitor proliferation(GO:0070447)
0.0 0.2 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.0 0.4 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.1 GO:0038166 angiotensin-activated signaling pathway(GO:0038166)
0.0 0.9 GO:0007218 neuropeptide signaling pathway(GO:0007218)
0.0 0.1 GO:1901550 regulation of endothelial cell development(GO:1901550) regulation of establishment of endothelial barrier(GO:1903140)
0.0 0.1 GO:0006642 triglyceride mobilization(GO:0006642)
0.0 0.2 GO:0006620 posttranslational protein targeting to membrane(GO:0006620)
0.0 0.0 GO:0030450 regulation of complement activation, classical pathway(GO:0030450)
0.0 1.4 GO:0008203 cholesterol metabolic process(GO:0008203)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.1 GO:0098843 postsynaptic endocytic zone(GO:0098843)
0.2 2.3 GO:0042589 zymogen granule membrane(GO:0042589)
0.1 1.0 GO:0005579 membrane attack complex(GO:0005579)
0.1 1.4 GO:0042588 zymogen granule(GO:0042588)
0.1 1.3 GO:0035253 ciliary rootlet(GO:0035253)
0.1 0.4 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.1 0.8 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0 1.0 GO:0031528 microvillus membrane(GO:0031528)
0.0 0.1 GO:0099522 region of cytosol(GO:0099522) postsynaptic cytosol(GO:0099524)
0.0 0.2 GO:0035068 micro-ribonucleoprotein complex(GO:0035068)
0.0 2.5 GO:0005791 rough endoplasmic reticulum(GO:0005791)
0.0 0.6 GO:0042611 MHC protein complex(GO:0042611)
0.0 0.3 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 0.1 GO:0030015 CCR4-NOT core complex(GO:0030015)
0.0 0.3 GO:0070938 contractile ring(GO:0070938)
0.0 0.1 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 0.3 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 1.9 GO:0005814 centriole(GO:0005814)
0.0 3.0 GO:0042579 peroxisome(GO:0005777) microbody(GO:0042579)
0.0 0.4 GO:0042101 T cell receptor complex(GO:0042101)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 2.9 GO:0003986 acetyl-CoA hydrolase activity(GO:0003986)
0.6 4.0 GO:0004556 alpha-amylase activity(GO:0004556)
0.4 1.1 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798)
0.2 1.0 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.2 1.3 GO:0099609 microtubule lateral binding(GO:0099609)
0.2 0.5 GO:0004974 leukotriene receptor activity(GO:0004974)
0.2 0.6 GO:0004510 tryptophan 5-monooxygenase activity(GO:0004510)
0.2 0.5 GO:0018479 benzaldehyde dehydrogenase (NAD+) activity(GO:0018479)
0.2 2.3 GO:0047372 acylglycerol lipase activity(GO:0047372)
0.1 0.4 GO:0003829 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity(GO:0003829)
0.1 0.6 GO:0004499 N,N-dimethylaniline monooxygenase activity(GO:0004499)
0.1 0.6 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.1 0.8 GO:0036122 BMP binding(GO:0036122)
0.1 1.9 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.1 0.3 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.1 0.3 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.0 0.5 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.0 1.0 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 2.8 GO:0005179 hormone activity(GO:0005179)
0.0 0.4 GO:0015643 toxic substance binding(GO:0015643)
0.0 0.3 GO:0003847 1-alkyl-2-acetylglycerophosphocholine esterase activity(GO:0003847)
0.0 0.8 GO:0042605 peptide antigen binding(GO:0042605)
0.0 0.3 GO:0004886 9-cis retinoic acid receptor activity(GO:0004886)
0.0 0.1 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.0 0.4 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 0.2 GO:0015143 urate transmembrane transporter activity(GO:0015143) salt transmembrane transporter activity(GO:1901702)
0.0 0.3 GO:0070330 aromatase activity(GO:0070330)
0.0 3.1 GO:0004252 serine-type endopeptidase activity(GO:0004252)
0.0 0.1 GO:0035473 lipase binding(GO:0035473)
0.0 0.3 GO:0017166 vinculin binding(GO:0017166)
0.0 0.4 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.2 GO:0032557 pyrimidine ribonucleotide binding(GO:0032557) uridylyltransferase activity(GO:0070569)
0.0 0.6 GO:0005070 SH3/SH2 adaptor activity(GO:0005070)
0.0 0.6 GO:0004364 glutathione transferase activity(GO:0004364)
0.0 0.1 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 0.1 GO:0015091 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.0 0.4 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.2 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.3 GO:0005521 lamin binding(GO:0005521)
0.0 0.0 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 0.1 GO:0004865 protein serine/threonine phosphatase inhibitor activity(GO:0004865)
0.0 1.4 GO:0008083 growth factor activity(GO:0008083)
0.0 0.4 GO:0000062 fatty-acyl-CoA binding(GO:0000062)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.3 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 0.4 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 0.6 PID PDGFRA PATHWAY PDGFR-alpha signaling pathway
0.0 0.5 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 0.4 PID WNT CANONICAL PATHWAY Canonical Wnt signaling pathway
0.0 1.0 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.4 PID ARF 3PATHWAY Arf1 pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.1 1.3 REACTOME INSULIN SYNTHESIS AND PROCESSING Genes involved in Insulin Synthesis and Processing
0.1 1.0 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.0 0.5 REACTOME EICOSANOID LIGAND BINDING RECEPTORS Genes involved in Eicosanoid ligand-binding receptors
0.0 0.7 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 2.3 REACTOME LIPID DIGESTION MOBILIZATION AND TRANSPORT Genes involved in Lipid digestion, mobilization, and transport
0.0 1.0 REACTOME COMPLEMENT CASCADE Genes involved in Complement cascade
0.0 0.5 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.5 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.8 REACTOME SIGNALING BY BMP Genes involved in Signaling by BMP
0.0 0.8 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 1.2 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors
0.0 0.7 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 0.4 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.0 0.2 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.4 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.6 REACTOME CLASS B 2 SECRETIN FAMILY RECEPTORS Genes involved in Class B/2 (Secretin family receptors)
0.0 0.4 REACTOME O LINKED GLYCOSYLATION OF MUCINS Genes involved in O-linked glycosylation of mucins
0.0 0.1 REACTOME NEF MEDIATES DOWN MODULATION OF CELL SURFACE RECEPTORS BY RECRUITING THEM TO CLATHRIN ADAPTERS Genes involved in Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters
0.0 0.4 REACTOME SMAD2 SMAD3 SMAD4 HETEROTRIMER REGULATES TRANSCRIPTION Genes involved in SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription
0.0 0.2 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.4 REACTOME DOWNSTREAM TCR SIGNALING Genes involved in Downstream TCR signaling