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2D miR_HR1_12

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Results for Esrrg

Z-value: 0.84

Motif logo

Transcription factors associated with Esrrg

Gene Symbol Gene ID Gene Info
ENSMUSG00000026610.7 estrogen-related receptor gamma

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Esrrgmm10_v2_chr1_+_187997821_1879978340.847.0e-04Click!

Activity profile of Esrrg motif

Sorted Z-values of Esrrg motif

Promoter Log-likelihood Transcript Gene Gene Info
chr15_-_79285470 2.30 ENSMUST00000170955.1
BAI1-associated protein 2-like 2
chr9_+_55326913 2.20 ENSMUST00000085754.3
ENSMUST00000034862.4
expressed sequence AI118078
chr19_-_43524462 1.53 ENSMUST00000026196.7
glutamate oxaloacetate transaminase 1, soluble
chr2_+_32587057 1.52 ENSMUST00000102818.4
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 4
chr2_+_131186942 1.47 ENSMUST00000028804.8
ENSMUST00000079857.8
cell division cycle 25B
chr15_-_79285502 1.47 ENSMUST00000165408.1
BAI1-associated protein 2-like 2
chr2_+_155611175 1.41 ENSMUST00000092995.5
myosin, heavy chain 7B, cardiac muscle, beta
chr6_+_113531675 1.38 ENSMUST00000036340.5
ENSMUST00000101051.2
Fanconi anemia, complementation group D2
chr10_+_128083273 1.36 ENSMUST00000026459.5
ATP synthase, H+ transporting mitochondrial F1 complex, beta subunit
chr15_+_78430086 1.34 ENSMUST00000162808.1
potassium channel tetramerisation domain containing 17
chr2_-_73911323 1.27 ENSMUST00000111996.1
ENSMUST00000018914.2
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C3 (subunit 9)
chr7_-_4445181 1.13 ENSMUST00000138798.1
retinol dehydrogenase 13 (all-trans and 9-cis)
chr19_-_53371766 1.10 ENSMUST00000086887.1
predicted gene 10197
chr11_-_100441795 0.99 ENSMUST00000107398.1
5'-nucleotidase, cytosolic IIIB
chrX_-_111463149 0.87 ENSMUST00000096348.3
ENSMUST00000113428.2
ribosomal protein S6 kinase polypeptide 6
chr14_+_25694170 0.86 ENSMUST00000022419.6
peptidylprolyl isomerase F (cyclophilin F)
chr9_+_54586450 0.81 ENSMUST00000167866.1
isocitrate dehydrogenase 3 (NAD+) alpha
chr7_-_4445595 0.80 ENSMUST00000119485.1
retinol dehydrogenase 13 (all-trans and 9-cis)
chr2_+_121357714 0.78 ENSMUST00000125812.1
ENSMUST00000078222.2
ENSMUST00000125221.1
ENSMUST00000150271.1
creatine kinase, mitochondrial 1, ubiquitous
chr12_-_83951355 0.77 ENSMUST00000181399.1
predicted gene, 26571
chr19_-_4839286 0.75 ENSMUST00000037246.5
copper chaperone for superoxide dismutase
chr15_-_76199835 0.75 ENSMUST00000054449.7
ENSMUST00000169714.1
ENSMUST00000165453.1
plectin
chr10_-_80855187 0.73 ENSMUST00000035775.8
LSM7 homolog, U6 small nuclear RNA associated (S. cerevisiae)
chr19_+_41911851 0.69 ENSMUST00000011896.6
phosphoglycerate mutase 1
chr19_+_47090748 0.68 ENSMUST00000072141.2
programmed cell death 11
chr6_-_125165576 0.67 ENSMUST00000183272.1
ENSMUST00000182052.1
ENSMUST00000182277.1
glyceraldehyde-3-phosphate dehydrogenase
chr4_+_141115660 0.66 ENSMUST00000181450.1
RIKEN cDNA 4921514A10 gene
chr2_+_121358591 0.65 ENSMUST00000000317.6
ENSMUST00000129130.1
creatine kinase, mitochondrial 1, ubiquitous
chr9_-_43116514 0.64 ENSMUST00000061833.4
transmembrane protein 136
chr16_+_32608973 0.64 ENSMUST00000120680.1
transferrin receptor
chr2_+_140170641 0.62 ENSMUST00000044825.4
NADH dehydrogenase (ubiquinone) complex I, assembly factor 5
chr1_-_191907527 0.62 ENSMUST00000069573.5
RIKEN cDNA 1700034H15 gene
chr2_+_178119166 0.61 ENSMUST00000108916.1
phosphatase and actin regulator 3
chr7_-_4445637 0.60 ENSMUST00000008579.7
retinol dehydrogenase 13 (all-trans and 9-cis)
chr4_+_128993224 0.58 ENSMUST00000030583.6
ENSMUST00000102604.4
adenylate kinase 2
chr8_-_70523085 0.58 ENSMUST00000137610.1
ENSMUST00000121623.1
ENSMUST00000093456.5
ENSMUST00000118850.1
KxDL motif containing 1
chr14_-_21848924 0.58 ENSMUST00000124549.1
catechol-O-methyltransferase domain containing 1
chr2_-_103073335 0.58 ENSMUST00000132449.1
ENSMUST00000111183.1
ENSMUST00000011058.2
pyruvate dehydrogenase complex, component X
chr2_-_10080055 0.57 ENSMUST00000130067.1
ENSMUST00000139810.1
ATP synthase, H+ transporting, mitochondrial F1 complex, gamma polypeptide 1
chr14_+_20929416 0.57 ENSMUST00000022369.7
vinculin
chr2_-_140170528 0.57 ENSMUST00000046030.7
ESF1, nucleolar pre-rRNA processing protein, homolog (S. cerevisiae)
chr1_+_6734827 0.56 ENSMUST00000139838.1
suppression of tumorigenicity 18
chr2_+_178118975 0.54 ENSMUST00000108917.1
phosphatase and actin regulator 3
chr17_-_45474839 0.54 ENSMUST00000024731.8
spermatogenesis associated, serine-rich 1
chr12_-_71136611 0.54 ENSMUST00000021486.8
ENSMUST00000166120.1
translocase of inner mitochondrial membrane 9
chr7_-_116237767 0.53 ENSMUST00000182834.1
pleckstrin homology domain containing, family A member 7
chr11_-_97573929 0.52 ENSMUST00000126287.1
ENSMUST00000107590.1
SRC kinase signaling inhibitor 1
chr4_+_13751297 0.51 ENSMUST00000105566.2
runt-related transcription factor 1; translocated to, 1 (cyclin D-related)
chr1_-_64122256 0.50 ENSMUST00000135075.1
Kruppel-like factor 7 (ubiquitous)
chr3_+_68869563 0.50 ENSMUST00000054551.2
RIKEN cDNA 1110032F04 gene
chr15_+_76343504 0.48 ENSMUST00000023210.6
cytochrome c-1
chr17_+_26123514 0.47 ENSMUST00000025014.8
mitochondrial ribosomal protein L28
chr5_-_49285653 0.47 ENSMUST00000175660.1
Kv channel interacting protein 4
chr2_+_121295437 0.47 ENSMUST00000110639.1
microtubule-associated protein 1 A
chr10_-_43540945 0.44 ENSMUST00000147196.1
ENSMUST00000019932.3
RIKEN cDNA 1700021F05 gene
chr3_+_85574109 0.44 ENSMUST00000127348.1
ENSMUST00000107672.1
ENSMUST00000107674.1
PET112 homolog (S. cerevisiae)
chr4_+_140961203 0.43 ENSMUST00000010007.8
succinate dehydrogenase complex, subunit B, iron sulfur (Ip)
chr9_-_54661666 0.42 ENSMUST00000128624.1
acyl-CoA synthetase bubblegum family member 1
chr17_-_81649607 0.42 ENSMUST00000163680.2
ENSMUST00000086538.3
ENSMUST00000163123.1
solute carrier family 8 (sodium/calcium exchanger), member 1
chr16_+_32608920 0.42 ENSMUST00000023486.8
transferrin receptor
chr1_+_131910458 0.40 ENSMUST00000062264.6
nuclear casein kinase and cyclin-dependent kinase substrate 1
chr17_-_35667546 0.40 ENSMUST00000043674.8
valyl-tRNA synthetase 2, mitochondrial (putative)
chr7_+_120635176 0.39 ENSMUST00000033176.5
ubiquinol cytochrome c reductase core protein 2
chr6_+_91157373 0.39 ENSMUST00000155007.1
histone deacetylase 11
chr7_+_45575100 0.39 ENSMUST00000140077.1
branched chain aminotransferase 2, mitochondrial
chr7_-_17027853 0.38 ENSMUST00000003183.5
protein phosphatase 5, catalytic subunit
chr18_-_67449083 0.38 ENSMUST00000025408.8
AFG3(ATPase family gene 3)-like 2 (yeast)
chr16_-_91931643 0.38 ENSMUST00000023677.3
ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit
chrX_-_8145713 0.38 ENSMUST00000115615.2
ENSMUST00000115616.1
ENSMUST00000115621.2
RNA binding motif protein 3
chr11_-_53430779 0.38 ENSMUST00000061326.4
ENSMUST00000109021.3
ubiquinol-cytochrome c reductase, complex III subunit VII
chrX_-_8145679 0.37 ENSMUST00000115619.1
ENSMUST00000115617.3
ENSMUST00000040010.3
RNA binding motif protein 3
chr18_+_45268876 0.37 ENSMUST00000183850.1
ENSMUST00000066890.7
potassium intermediate/small conductance calcium-activated channel, subfamily N, member 2
chr18_+_77773956 0.36 ENSMUST00000114748.1
ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1
chr7_-_17027807 0.36 ENSMUST00000142597.1
protein phosphatase 5, catalytic subunit
chr9_-_44980390 0.35 ENSMUST00000002101.5
ENSMUST00000160886.1
CD3 antigen, gamma polypeptide
chr1_+_63176818 0.35 ENSMUST00000129339.1
eukaryotic translation elongation factor 1 beta 2
chr3_-_32737147 0.35 ENSMUST00000043966.7
mitochondrial ribosomal protein L47
chr4_-_40279389 0.35 ENSMUST00000108108.2
ENSMUST00000095128.3
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 6
chrX_-_136976859 0.33 ENSMUST00000127404.1
ENSMUST00000113071.1
thymosin beta 15b like
thymosin beta 15b1
chr2_+_127587214 0.32 ENSMUST00000028852.6
mitochondrial ribosomal protein S5
chr1_-_131097535 0.32 ENSMUST00000016672.4
MAP kinase-activated protein kinase 2
chr6_-_71823805 0.31 ENSMUST00000065103.2
mitochondrial ribosomal protein L35
chr11_+_70023905 0.31 ENSMUST00000124568.2
discs, large homolog 4 (Drosophila)
chr2_-_26021532 0.31 ENSMUST00000136750.1
ubiquitin associated domain containing 1
chr16_+_84834901 0.30 ENSMUST00000114184.1
GA repeat binding protein, alpha
chr3_+_32736990 0.30 ENSMUST00000127477.1
ENSMUST00000121778.1
ENSMUST00000154257.1
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 5
chr2_-_26021679 0.30 ENSMUST00000036509.7
ubiquitin associated domain containing 1
chr16_-_8637662 0.30 ENSMUST00000052505.8
transmembrane protein 186
chr11_-_115267236 0.29 ENSMUST00000106554.1
glutamate receptor, ionotropic, NMDA2C (epsilon 3)
chr4_-_126202583 0.28 ENSMUST00000106142.1
ENSMUST00000169403.1
ENSMUST00000130334.1
thyroid hormone receptor associated protein 3
chrX_-_72656135 0.28 ENSMUST00000055966.6
gamma-aminobutyric acid (GABA) A receptor, subunit alpha 3
chr17_-_32420965 0.28 ENSMUST00000170392.1
peptidoglycan recognition protein 2
chr2_+_130576170 0.27 ENSMUST00000028764.5
oxytocin
chr11_-_102407315 0.27 ENSMUST00000149777.1
ENSMUST00000154001.1
solute carrier family 25, member 39
chr19_+_37207528 0.27 ENSMUST00000024078.7
ENSMUST00000112391.1
membrane-associated ring finger (C3HC4) 5
chr18_-_34954302 0.26 ENSMUST00000025217.8
heat shock protein 9
chr7_-_100583072 0.26 ENSMUST00000152876.1
ENSMUST00000150042.1
mitochondrial ribosomal protein L48
chr8_+_70863127 0.25 ENSMUST00000050921.2
RIKEN cDNA A230052G05 gene
chr8_-_94838255 0.25 ENSMUST00000161762.1
ENSMUST00000162538.1
cytokine induced apoptosis inhibitor 1
chr11_+_6415443 0.25 ENSMUST00000132846.1
peptidylprolyl isomerase A
chrX_+_75382384 0.25 ENSMUST00000033541.4
FUN14 domain containing 2
chr1_+_36691487 0.24 ENSMUST00000081180.4
cytochrome c oxidase subunit Vb
chr12_-_84194007 0.23 ENSMUST00000110294.1
ELM2 and Myb/SANT-like domain containing 1
chr11_+_76407143 0.23 ENSMUST00000021203.6
ENSMUST00000152183.1
translocase of inner mitochondrial membrane 22
chr16_-_5013505 0.23 ENSMUST00000023191.10
ENSMUST00000090453.5
rogdi homolog (Drosophila)
chr15_-_98195542 0.23 ENSMUST00000165379.1
ENSMUST00000142443.1
olfactory receptor 288
chr16_-_56024628 0.22 ENSMUST00000119981.1
ENSMUST00000096021.3
PEST proteolytic signal containing nuclear protein
chr14_+_58076507 0.21 ENSMUST00000166770.1
fibroblast growth factor 9
chr11_-_101095367 0.21 ENSMUST00000019447.8
proteasome (prosome, macropain) 26S subunit, ATPase 3, interacting protein
chr19_+_6400611 0.21 ENSMUST00000113467.1
RAS, guanyl releasing protein 2
chr17_+_29032664 0.21 ENSMUST00000130216.1
serine/arginine-rich splicing factor 3
chr7_-_141429351 0.20 ENSMUST00000164387.1
ENSMUST00000137488.1
ENSMUST00000084436.3
cell cycle exit and neuronal differentiation 1
chr5_+_32863700 0.19 ENSMUST00000149350.1
ENSMUST00000118698.1
ENSMUST00000150130.1
ENSMUST00000087897.4
ENSMUST00000119705.1
ENSMUST00000125574.1
ENSMUST00000049780.6
DEP domain containing 5
chr7_-_35396708 0.19 ENSMUST00000154597.1
ENSMUST00000032704.5
RIKEN cDNA C230052I12 gene
chr13_+_54192106 0.18 ENSMUST00000038101.3
histamine receptor H2
chr6_-_92183972 0.17 ENSMUST00000140438.1
mitochondrial ribosomal protein S25
chr15_-_99457742 0.17 ENSMUST00000023747.7
NCK-associated protein 5-like
chr16_+_45158725 0.17 ENSMUST00000023343.3
autophagy related 3
chr5_+_123344440 0.16 ENSMUST00000031391.2
ENSMUST00000117971.1
B cell CLL/lymphoma 7A
chr14_-_36919314 0.16 ENSMUST00000182797.1
coiled-coil serine rich 2
chr2_+_130012336 0.16 ENSMUST00000110299.2
transglutaminase 3, E polypeptide
chr18_-_36744518 0.15 ENSMUST00000014438.4
NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2
chr7_+_34251038 0.14 ENSMUST00000105172.1
predicted gene 6096
chr4_+_124880899 0.14 ENSMUST00000059343.6
Eph receptor A10
chr11_-_94677404 0.14 ENSMUST00000116349.2
xylosyltransferase II
chr11_-_84870812 0.13 ENSMUST00000168434.1
gametogenetin binding protein 2
chr7_-_105574324 0.13 ENSMUST00000081165.7
amyloid beta (A4) precursor protein-binding, family B, member 1
chr4_-_108780782 0.13 ENSMUST00000106657.1
zinc finger, FYVE domain containing 9
chr6_+_83349446 0.13 ENSMUST00000136501.1
bolA-like 3 (E. coli)
chr15_-_35938009 0.12 ENSMUST00000156915.1
cytochrome c oxidase subunit VIc
chr19_-_47090610 0.11 ENSMUST00000096014.3
upregulated during skeletal muscle growth 5
chr14_-_36919513 0.11 ENSMUST00000182042.1
coiled-coil serine rich 2
chr11_-_84870646 0.11 ENSMUST00000018547.2
gametogenetin binding protein 2
chr2_+_155517948 0.10 ENSMUST00000029135.8
ENSMUST00000065973.2
ENSMUST00000103142.5
acyl-CoA synthetase short-chain family member 2
chr11_-_84870712 0.10 ENSMUST00000170741.1
ENSMUST00000172405.1
ENSMUST00000100686.3
ENSMUST00000108081.2
gametogenetin binding protein 2
chr2_+_164785994 0.09 ENSMUST00000152471.1
sorting nexin family member 21
chr19_-_4334001 0.09 ENSMUST00000176653.1
lysine (K)-specific demethylase 2A
chr5_+_118065360 0.09 ENSMUST00000031305.3
predicted gene 9754
chr4_-_108780503 0.09 ENSMUST00000106658.1
zinc finger, FYVE domain containing 9
chr1_+_127204986 0.09 ENSMUST00000038361.4
mannoside acetylglucosaminyltransferase 5
chr8_+_94838321 0.09 ENSMUST00000034234.8
ENSMUST00000159871.1
coenzyme Q9 homolog (yeast)
chr11_+_100441882 0.09 ENSMUST00000001599.3
ENSMUST00000107395.2
kelch-like 10
chr16_+_21891969 0.09 ENSMUST00000042065.6
mitogen-activated protein kinase kinase kinase 13
chr1_+_36471590 0.09 ENSMUST00000153128.1
cyclin M4
chr4_-_82505707 0.09 ENSMUST00000107248.1
ENSMUST00000107247.1
nuclear factor I/B
chr2_+_164785823 0.08 ENSMUST00000174070.1
ENSMUST00000172577.1
ENSMUST00000056181.6
sorting nexin family member 21
chr7_-_81706905 0.07 ENSMUST00000026922.7
homer homolog 2 (Drosophila)
chr4_-_82505749 0.07 ENSMUST00000107245.2
ENSMUST00000107246.1
nuclear factor I/B
chrX_-_75382615 0.06 ENSMUST00000147349.1
coagulation factor VIII
chr10_-_84440591 0.06 ENSMUST00000020220.8
NUAK family, SNF1-like kinase, 1
chrX_+_56963325 0.05 ENSMUST00000096431.3
G protein-coupled receptor 112
chr7_-_126475082 0.05 ENSMUST00000032978.6
SH2B adaptor protein 1
chr2_+_158794807 0.05 ENSMUST00000029186.7
ENSMUST00000109478.2
ENSMUST00000156893.1
DEAH (Asp-Glu-Ala-His) box polypeptide 35
chr5_+_123343834 0.05 ENSMUST00000120593.1
B cell CLL/lymphoma 7A
chr16_-_19883873 0.04 ENSMUST00000100083.3
RIKEN cDNA A930003A15 gene
chr16_+_4684070 0.04 ENSMUST00000060067.5
ENSMUST00000115854.3
DnaJ (Hsp40) homolog, subfamily A, member 3
chr9_-_42461414 0.03 ENSMUST00000066179.7
tubulin folding cofactor E-like
chr11_+_94044331 0.03 ENSMUST00000024979.8
sperm associated antigen 9
chr4_-_128962420 0.03 ENSMUST00000119354.1
ENSMUST00000106068.1
ENSMUST00000030581.3
arginine decarboxylase
chr2_+_29965560 0.03 ENSMUST00000113717.1
ENSMUST00000113719.2
ENSMUST00000100225.2
ENSMUST00000113741.1
ENSMUST00000095083.4
ENSMUST00000046257.7
spectrin alpha, non-erythrocytic 1
chr4_+_99955715 0.03 ENSMUST00000102783.4
phosphoglucomutase 2
chr11_+_70844745 0.03 ENSMUST00000076270.6
ENSMUST00000179114.1
ENSMUST00000100928.4
ENSMUST00000177731.1
ENSMUST00000108533.3
ENSMUST00000081362.6
ENSMUST00000178245.1
rabaptin, RAB GTPase binding effector protein 1
chr17_-_17624458 0.02 ENSMUST00000041047.2
leucyl/cystinyl aminopeptidase
chr15_-_99457712 0.02 ENSMUST00000161948.1
NCK-associated protein 5-like
chr13_-_102905740 0.02 ENSMUST00000167462.1
microtubule associated serine/threonine kinase family member 4
chr14_+_21500879 0.00 ENSMUST00000182964.1
K(lysine) acetyltransferase 6B
chr16_+_10545390 0.00 ENSMUST00000115827.1
ENSMUST00000038145.6
ENSMUST00000150894.1
C-type lectin domain family 16, member A
chr7_-_141429433 0.00 ENSMUST00000124444.1
cell cycle exit and neuronal differentiation 1
chr14_+_78849171 0.00 ENSMUST00000040990.5
von Willebrand factor A domain containing 8

Network of associatons between targets according to the STRING database.

First level regulatory network of Esrrg

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0006114 glycerol biosynthetic process(GO:0006114) aspartate biosynthetic process(GO:0006532) aspartate catabolic process(GO:0006533)
0.3 0.9 GO:1902445 regulation of mitochondrial membrane permeability involved in programmed necrotic cell death(GO:1902445)
0.3 2.5 GO:0009644 response to high light intensity(GO:0009644)
0.2 1.4 GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
0.2 1.1 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.2 1.5 GO:0007144 female meiosis I(GO:0007144)
0.2 0.7 GO:0035606 peptidyl-cysteine S-trans-nitrosylation(GO:0035606)
0.2 3.8 GO:2000251 positive regulation of actin cytoskeleton reorganization(GO:2000251)
0.2 0.8 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.1 1.4 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.1 0.7 GO:0043456 regulation of pentose-phosphate shunt(GO:0043456)
0.1 0.4 GO:0060382 release from viral latency(GO:0019046) regulation of DNA strand elongation(GO:0060382)
0.1 0.4 GO:0006550 isoleucine catabolic process(GO:0006550)
0.1 0.8 GO:0006102 isocitrate metabolic process(GO:0006102)
0.1 0.4 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
0.1 0.6 GO:0006172 ADP biosynthetic process(GO:0006172)
0.1 0.3 GO:0032824 natural killer cell differentiation involved in immune response(GO:0002325) negative regulation of natural killer cell differentiation(GO:0032824) regulation of natural killer cell differentiation involved in immune response(GO:0032826) negative regulation of natural killer cell differentiation involved in immune response(GO:0032827)
0.1 0.7 GO:0016576 histone dephosphorylation(GO:0016576)
0.1 2.2 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.1 0.3 GO:0043133 hindgut contraction(GO:0043133) regulation of hindgut contraction(GO:0043134)
0.1 0.5 GO:0045218 zonula adherens maintenance(GO:0045218)
0.1 0.4 GO:0021539 subthalamus development(GO:0021539)
0.1 1.1 GO:0033572 transferrin transport(GO:0033572)
0.1 0.6 GO:0061732 mitochondrial acetyl-CoA biosynthetic process from pyruvate(GO:0061732)
0.1 0.8 GO:0034982 mitochondrial protein processing(GO:0034982)
0.1 0.2 GO:0021941 radial glia guided migration of cerebellar granule cell(GO:0021933) negative regulation of cerebellar granule cell precursor proliferation(GO:0021941)
0.1 0.3 GO:0033140 negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140)
0.1 0.3 GO:1902037 negative regulation of hematopoietic stem cell differentiation(GO:1902037)
0.1 0.3 GO:0044351 macropinocytosis(GO:0044351)
0.1 0.9 GO:2000381 negative regulation of mesoderm development(GO:2000381)
0.1 0.4 GO:0071313 cellular response to caffeine(GO:0071313)
0.1 0.2 GO:0001698 gastrin-induced gastric acid secretion(GO:0001698)
0.1 0.7 GO:0031581 hemidesmosome assembly(GO:0031581)
0.1 0.4 GO:0098914 membrane repolarization during atrial cardiac muscle cell action potential(GO:0098914)
0.1 0.6 GO:2001269 positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269)
0.0 0.6 GO:0090136 epithelial cell-cell adhesion(GO:0090136)
0.0 0.3 GO:1903350 response to dopamine(GO:1903350) cellular response to dopamine(GO:1903351)
0.0 0.3 GO:0042989 sequestering of actin monomers(GO:0042989)
0.0 1.3 GO:0032469 endoplasmic reticulum calcium ion homeostasis(GO:0032469)
0.0 1.4 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.7 GO:0000466 maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000466)
0.0 0.1 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.0 1.5 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.0 0.3 GO:0099628 receptor diffusion trapping(GO:0098953) postsynaptic neurotransmitter receptor diffusion trapping(GO:0098970) neurotransmitter receptor diffusion trapping(GO:0099628)
0.0 0.1 GO:0006083 acetate metabolic process(GO:0006083) short-chain fatty acid biosynthetic process(GO:0051790)
0.0 0.2 GO:0043653 mitochondrial fragmentation involved in apoptotic process(GO:0043653)
0.0 0.5 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0 0.1 GO:0090598 male genitalia morphogenesis(GO:0048808) male anatomical structure morphogenesis(GO:0090598)
0.0 0.7 GO:0035196 production of miRNAs involved in gene silencing by miRNA(GO:0035196)
0.0 0.3 GO:0090344 negative regulation of cell aging(GO:0090344)
0.0 0.3 GO:0031163 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.0 0.7 GO:0051353 positive regulation of oxidoreductase activity(GO:0051353)
0.0 0.1 GO:0033184 positive regulation of histone ubiquitination(GO:0033184)
0.0 0.2 GO:0006105 succinate metabolic process(GO:0006105)
0.0 0.1 GO:0070166 enamel mineralization(GO:0070166)
0.0 0.2 GO:0007183 SMAD protein complex assembly(GO:0007183)
0.0 0.0 GO:0060331 negative regulation of response to interferon-gamma(GO:0060331) negative regulation of interferon-gamma-mediated signaling pathway(GO:0060336)
0.0 0.2 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 1.2 GO:0032091 negative regulation of protein binding(GO:0032091)
0.0 0.3 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.4 GO:0000038 very long-chain fatty acid metabolic process(GO:0000038)
0.0 0.2 GO:0031424 keratinization(GO:0031424)
0.0 0.2 GO:0034389 lipid particle organization(GO:0034389)
0.0 0.5 GO:0007026 negative regulation of microtubule depolymerization(GO:0007026)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 3.8 GO:0071439 clathrin complex(GO:0071439)
0.3 2.3 GO:0045261 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.1 1.3 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750)
0.1 1.7 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1 0.6 GO:0097226 sperm mitochondrial sheath(GO:0097226)
0.1 0.5 GO:0042719 mitochondrial intermembrane space protein transporter complex(GO:0042719)
0.1 0.7 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.1 0.6 GO:0031314 extrinsic component of mitochondrial inner membrane(GO:0031314)
0.1 1.1 GO:1990712 HFE-transferrin receptor complex(GO:1990712)
0.1 0.4 GO:0005745 m-AAA complex(GO:0005745)
0.1 0.7 GO:0097452 GAIT complex(GO:0097452)
0.1 0.7 GO:0097512 cardiac myofibril(GO:0097512)
0.1 0.6 GO:0045254 pyruvate dehydrogenase complex(GO:0045254)
0.1 0.1 GO:1990812 growth cone filopodium(GO:1990812)
0.1 0.4 GO:0005853 eukaryotic translation elongation factor 1 complex(GO:0005853)
0.1 0.1 GO:0005753 mitochondrial proton-transporting ATP synthase complex(GO:0005753)
0.0 0.7 GO:1990635 proximal dendrite(GO:1990635)
0.0 0.5 GO:0005915 zonula adherens(GO:0005915)
0.0 0.2 GO:0045281 mitochondrial respiratory chain complex II, succinate dehydrogenase complex (ubiquinone)(GO:0005749) succinate dehydrogenase complex (ubiquinone)(GO:0045257) respiratory chain complex II(GO:0045273) succinate dehydrogenase complex(GO:0045281) fumarate reductase complex(GO:0045283)
0.0 0.4 GO:0042105 alpha-beta T cell receptor complex(GO:0042105)
0.0 0.2 GO:1990130 Iml1 complex(GO:1990130)
0.0 0.7 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.6 GO:0005916 fascia adherens(GO:0005916)
0.0 0.6 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 1.4 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.4 GO:0044300 cerebellar mossy fiber(GO:0044300)
0.0 1.6 GO:0044455 mitochondrial membrane part(GO:0044455)
0.0 0.7 GO:0032040 small-subunit processome(GO:0032040)
0.0 0.3 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 1.4 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 2.1 GO:0098798 mitochondrial protein complex(GO:0098798)
0.0 0.2 GO:0001533 cornified envelope(GO:0001533)
0.0 0.5 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.3 GO:1902711 GABA-A receptor complex(GO:1902711)
0.0 0.2 GO:0000153 cytoplasmic ubiquitin ligase complex(GO:0000153)
0.0 0.9 GO:0015934 large ribosomal subunit(GO:0015934)
0.0 1.5 GO:0000922 spindle pole(GO:0000922)
0.0 0.1 GO:0008385 IkappaB kinase complex(GO:0008385)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0080130 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069) L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.4 1.1 GO:0004998 transferrin receptor activity(GO:0004998)
0.3 1.7 GO:0043532 angiostatin binding(GO:0043532)
0.3 0.8 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.2 0.7 GO:0004082 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.2 0.7 GO:0035605 peptidyl-cysteine S-nitrosylase activity(GO:0035605)
0.2 0.9 GO:0004111 creatine kinase activity(GO:0004111)
0.2 1.5 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.2 1.1 GO:0016018 cyclosporin A binding(GO:0016018)
0.1 0.7 GO:0016721 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.1 2.2 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.1 0.4 GO:0051538 3 iron, 4 sulfur cluster binding(GO:0051538)
0.1 0.4 GO:0086038 calcium:sodium antiporter activity involved in regulation of cardiac muscle cell membrane potential(GO:0086038)
0.1 0.4 GO:0004832 valine-tRNA ligase activity(GO:0004832)
0.1 0.6 GO:0004738 pyruvate dehydrogenase activity(GO:0004738) pyruvate dehydrogenase [NAD(P)+] activity(GO:0034603) pyruvate dehydrogenase (NAD+) activity(GO:0034604)
0.1 0.3 GO:0016019 N-acetylmuramoyl-L-alanine amidase activity(GO:0008745) peptidoglycan receptor activity(GO:0016019)
0.1 0.4 GO:0016286 small conductance calcium-activated potassium channel activity(GO:0016286)
0.1 0.7 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.1 0.4 GO:0052655 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.1 0.2 GO:0019776 Atg8 ligase activity(GO:0019776)
0.1 1.0 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.1 1.3 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.6 GO:0004017 adenylate kinase activity(GO:0004017)
0.0 0.4 GO:0008121 ubiquinol-cytochrome-c reductase activity(GO:0008121) oxidoreductase activity, acting on diphenols and related substances as donors, cytochrome as acceptor(GO:0016681)
0.0 0.1 GO:0030158 protein xylosyltransferase activity(GO:0030158)
0.0 1.4 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 0.5 GO:0070097 delta-catenin binding(GO:0070097)
0.0 0.6 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.3 GO:0004972 NMDA glutamate receptor activity(GO:0004972)
0.0 0.3 GO:0031811 G-protein coupled nucleotide receptor binding(GO:0031811) P2Y1 nucleotide receptor binding(GO:0031812)
0.0 0.4 GO:0031957 very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.1 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.0 1.1 GO:0008157 protein phosphatase 1 binding(GO:0008157)
0.0 0.3 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 0.2 GO:0004969 histamine receptor activity(GO:0004969)
0.0 0.6 GO:0008171 O-methyltransferase activity(GO:0008171)
0.0 0.7 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.1 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.1 GO:0030160 GKAP/Homer scaffold activity(GO:0030160)
0.0 0.2 GO:0015266 protein channel activity(GO:0015266)
0.0 0.1 GO:0030144 alpha-1,6-mannosylglycoprotein 6-beta-N-acetylglucosaminyltransferase activity(GO:0030144)
0.0 0.2 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.4 GO:0031078 histone deacetylase activity (H3-K14 specific)(GO:0031078) NAD-dependent histone deacetylase activity (H3-K14 specific)(GO:0032041)
0.0 0.4 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.7 GO:0001965 G-protein alpha-subunit binding(GO:0001965)
0.0 0.1 GO:0045322 unmethylated CpG binding(GO:0045322)
0.0 0.4 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.5 GO:0046966 thyroid hormone receptor binding(GO:0046966)
0.0 0.2 GO:0005545 1-phosphatidylinositol binding(GO:0005545)
0.0 0.3 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.3 GO:0004890 GABA-A receptor activity(GO:0004890)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.5 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 1.4 PID BARD1 PATHWAY BARD1 signaling events
0.0 1.1 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 1.7 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.7 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.1 1.4 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.1 1.6 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.1 1.5 REACTOME CYCLIN A B1 ASSOCIATED EVENTS DURING G2 M TRANSITION Genes involved in Cyclin A/B1 associated events during G2/M transition
0.1 1.5 REACTOME TERMINATION OF O GLYCAN BIOSYNTHESIS Genes involved in Termination of O-glycan biosynthesis
0.1 0.2 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.0 1.0 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.4 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 2.4 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 1.1 REACTOME TRANSFERRIN ENDOCYTOSIS AND RECYCLING Genes involved in Transferrin endocytosis and recycling
0.0 1.4 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.8 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 1.2 REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS Genes involved in CREB phosphorylation through the activation of Ras
0.0 0.6 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.4 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.0 0.3 REACTOME P38MAPK EVENTS Genes involved in p38MAPK events
0.0 0.8 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.4 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.4 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.3 REACTOME GABA A RECEPTOR ACTIVATION Genes involved in GABA A receptor activation
0.0 0.1 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.6 REACTOME SMOOTH MUSCLE CONTRACTION Genes involved in Smooth Muscle Contraction