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2D miR_HR1_12

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Results for Rarb

Z-value: 0.53

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Transcription factors associated with Rarb

Gene Symbol Gene ID Gene Info
ENSMUSG00000017491.8 retinoic acid receptor, beta

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Rarbmm10_v2_chr14_-_16575456_16575501-0.127.0e-01Click!

Activity profile of Rarb motif

Sorted Z-values of Rarb motif

Promoter Log-likelihood Transcript Gene Gene Info
chr3_+_88081997 1.84 ENSMUST00000071812.5
IQ motif containing GTPase activating protein 3
chr1_+_191821444 1.69 ENSMUST00000027931.7
NIMA (never in mitosis gene a)-related expressed kinase 2
chr10_-_126901315 0.99 ENSMUST00000026504.5
ENSMUST00000168520.1
XRCC6 binding protein 1
chr11_-_45944910 0.61 ENSMUST00000129820.1
U7 snRNP-specific Sm-like protein LSM11
chr2_+_30281043 0.60 ENSMUST00000143119.2
RP23-395P6.9
chr13_-_25270076 0.58 ENSMUST00000057866.6
neurensin 1
chr19_-_8786272 0.41 ENSMUST00000176610.1
ENSMUST00000177056.1
TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor
chr10_-_92722356 0.41 ENSMUST00000020163.6
neural precursor cell expressed, developmentally down-regulated gene 1
chr19_-_8786245 0.39 ENSMUST00000177216.1
TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor
chr8_+_106683052 0.39 ENSMUST00000048359.4
transport and golgi organization 6
chr19_-_8786408 0.34 ENSMUST00000176496.1
TAF6-like RNA polymerase II, p300/CBP-associated factor (PCAF)-associated factor
chr12_+_7977640 0.33 ENSMUST00000171271.1
ENSMUST00000037811.6
ENSMUST00000037520.7
apolipoprotein B
chr2_-_163417092 0.28 ENSMUST00000127038.1
oxidative stress responsive serine rich 1
chr5_+_92897981 0.24 ENSMUST00000113051.2
shroom family member 3
chr7_+_45617575 0.15 ENSMUST00000008605.5
fucosyltransferase 1
chr10_+_67185730 0.15 ENSMUST00000173689.1
jumonji domain containing 1C
chr17_+_12584183 0.13 ENSMUST00000046959.7
solute carrier family 22 (organic cation transporter), member 2
chr3_+_154711125 0.13 ENSMUST00000051862.6
RIKEN cDNA 4922501L14 gene
chr5_-_87092546 0.12 ENSMUST00000132667.1
ENSMUST00000145617.1
ENSMUST00000094649.4
UDP glucuronosyltransferase 2 family, polypeptide B36
chr6_-_85820965 0.12 ENSMUST00000032074.3
camello-like 5
chr9_-_46235631 0.12 ENSMUST00000118649.1
apolipoprotein C-III
chr7_+_127904079 0.10 ENSMUST00000071056.7
branched chain ketoacid dehydrogenase kinase
chr11_+_83409137 0.09 ENSMUST00000021022.3
RAS-like, family 10, member B
chr8_-_4105764 0.08 ENSMUST00000138439.1
ENSMUST00000145007.1
CD209f antigen
chr11_+_83409655 0.08 ENSMUST00000175848.1
ENSMUST00000108140.3
RAS-like, family 10, member B
chr6_-_85820936 0.06 ENSMUST00000174143.1
predicted gene 11128
chr1_+_90203980 0.06 ENSMUST00000065587.4
ENSMUST00000159654.1
atypical chemokine receptor 3
chr7_-_116031047 0.06 ENSMUST00000106612.1
SRY-box containing gene 6
chr15_-_98662858 0.05 ENSMUST00000162384.1
ENSMUST00000003450.8
DEAD (Asp-Glu-Ala-Asp) box polypeptide 23
chr19_+_44992127 0.04 ENSMUST00000179305.1
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
chr11_+_76904513 0.03 ENSMUST00000072633.3
transmembrane and immunoglobulin domain containing 1
chr2_+_3770673 0.02 ENSMUST00000177037.1
family with sequence similarity 107, member B
chr11_+_76904475 0.02 ENSMUST00000142166.1
transmembrane and immunoglobulin domain containing 1
chr7_+_35449035 0.02 ENSMUST00000118969.1
ENSMUST00000118383.1
solute carrier family 7 (cationic amino acid transporter, y+ system), member 9
chr19_+_28990476 0.01 ENSMUST00000050148.3
cell division cycle 37-like 1
chr5_-_87140318 0.00 ENSMUST00000067790.6
ENSMUST00000113327.1
UDP glucuronosyltransferase 2 family, polypeptide B5

Network of associatons between targets according to the STRING database.

First level regulatory network of Rarb

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.7 GO:0030997 regulation of centriole-centriole cohesion(GO:0030997)
0.1 1.8 GO:0033601 positive regulation of mammary gland epithelial cell proliferation(GO:0033601)
0.1 0.6 GO:0006398 mRNA 3'-end processing by stem-loop binding and cleavage(GO:0006398)
0.0 0.4 GO:0006642 triglyceride mobilization(GO:0006642)
0.0 0.2 GO:0003050 regulation of systemic arterial blood pressure by atrial natriuretic peptide(GO:0003050)
0.0 0.1 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.0 1.1 GO:0043966 histone H3 acetylation(GO:0043966)
0.0 0.4 GO:0071539 protein localization to centrosome(GO:0071539)
0.0 0.1 GO:0015697 quaternary ammonium group transport(GO:0015697)
0.0 0.2 GO:0036065 fucosylation(GO:0036065)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0005683 U7 snRNP(GO:0005683)
0.1 0.4 GO:0008274 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.1 1.1 GO:0030914 STAGA complex(GO:0030914)
0.0 0.4 GO:0034363 intermediate-density lipoprotein particle(GO:0034363)
0.0 0.1 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0 1.8 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 1.7 GO:0000794 condensed nuclear chromosome(GO:0000794)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.8 GO:0032027 myosin light chain binding(GO:0032027)
0.2 0.6 GO:0071209 U7 snRNA binding(GO:0071209)
0.1 0.2 GO:0031127 galactoside 2-alpha-L-fucosyltransferase activity(GO:0008107) alpha-(1,2)-fucosyltransferase activity(GO:0031127)
0.0 0.1 GO:0005333 norepinephrine transmembrane transporter activity(GO:0005333)
0.0 0.3 GO:0035473 lipase binding(GO:0035473)
0.0 0.1 GO:0070653 high-density lipoprotein particle receptor binding(GO:0070653)
0.0 1.1 GO:0004402 histone acetyltransferase activity(GO:0004402)
0.0 0.1 GO:0019958 C-X-C chemokine binding(GO:0019958)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.7 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 1.8 PID RAC1 PATHWAY RAC1 signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.7 REACTOME APC CDC20 MEDIATED DEGRADATION OF NEK2A Genes involved in APC-Cdc20 mediated degradation of Nek2A
0.1 0.6 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 0.4 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.4 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.1 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport