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2D miR_HR1_12

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Results for Trp53

Z-value: 1.08

Motif logo

Transcription factors associated with Trp53

Gene Symbol Gene ID Gene Info
ENSMUSG00000059552.7 transformation related protein 53

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Trp53mm10_v2_chr11_+_69580359_695803820.921.7e-05Click!

Activity profile of Trp53 motif

Sorted Z-values of Trp53 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr17_-_33890584 3.21 ENSMUST00000114361.2
ENSMUST00000173492.1
kinesin family member C1
chr17_-_33890539 2.91 ENSMUST00000173386.1
kinesin family member C1
chr17_+_29090969 2.84 ENSMUST00000119901.1
cyclin-dependent kinase inhibitor 1A (P21)
chr8_-_22185758 2.83 ENSMUST00000046916.7
cytoskeleton associated protein 2
chr11_-_40755201 2.39 ENSMUST00000020576.7
cyclin G1
chr15_+_62039216 2.07 ENSMUST00000183297.1
plasmacytoma variant translocation 1
chr15_+_85859689 1.77 ENSMUST00000170629.1
G two S phase expressed protein 1
chr2_+_152962485 1.66 ENSMUST00000099197.2
ENSMUST00000103155.3
tubulin tyrosine ligase-like family, member 9
chr15_-_102350692 1.61 ENSMUST00000041208.7
achalasia, adrenocortical insufficiency, alacrimia
chr9_-_106656081 1.57 ENSMUST00000023959.7
glutamate receptor, metabotropic 2
chr16_+_17144600 1.47 ENSMUST00000115702.1
YdjC homolog (bacterial)
chr11_-_102925086 1.42 ENSMUST00000021311.9
kinesin family member 18B
chr2_+_72285637 1.22 ENSMUST00000090824.5
ENSMUST00000135469.1
sterile alpha motif and leucine zipper containing kinase AZK
chr17_+_26917091 1.21 ENSMUST00000078961.4
kinesin family member C5B
chr16_-_17144415 1.21 ENSMUST00000115709.1
coiled-coil domain containing 116
chr2_+_129100995 1.16 ENSMUST00000103205.4
ENSMUST00000028874.7
polymerase (RNA) I polypeptide B
chr14_-_118925314 1.15 ENSMUST00000004055.8
DAZ interacting protein 1
chr7_+_16309577 1.14 ENSMUST00000002152.6
BCL2 binding component 3
chr1_-_79858627 1.03 ENSMUST00000027467.4
serine (or cysteine) peptidase inhibitor, clade E, member 2
chr8_-_106136890 0.95 ENSMUST00000115979.2
epithelial splicing regulatory protein 2
chr9_+_66946057 0.95 ENSMUST00000040917.7
ENSMUST00000127896.1
ribosomal protein S27-like
chr1_+_55237177 0.92 ENSMUST00000061334.8
methionine-tRNA synthetase 2 (mitochondrial)
chr5_+_8798139 0.84 ENSMUST00000009058.5
ATP-binding cassette, sub-family B (MDR/TAP), member 1B
chr10_+_57632108 0.82 ENSMUST00000177438.1
protein kinase inhibitor beta, cAMP dependent, testis specific
chr1_-_191907527 0.75 ENSMUST00000069573.5
RIKEN cDNA 1700034H15 gene
chr16_+_38458887 0.74 ENSMUST00000099816.2
CD80 antigen
chr11_+_4267095 0.73 ENSMUST00000040750.3
leukemia inhibitory factor
chr10_+_110745433 0.72 ENSMUST00000174857.1
ENSMUST00000073781.5
ENSMUST00000173471.1
ENSMUST00000173634.1
E2F transcription factor 7
chr2_-_69206146 0.71 ENSMUST00000127243.1
ENSMUST00000149643.1
ENSMUST00000167875.2
ENSMUST00000005365.8
SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae)
chr14_-_70653081 0.68 ENSMUST00000062629.4
nucleophosmin/nucleoplasmin 2
chr12_-_78906929 0.66 ENSMUST00000021544.7
pleckstrin 2
chr14_-_55944536 0.63 ENSMUST00000022834.6
chymase 1, mast cell
chr19_-_43524462 0.60 ENSMUST00000026196.7
glutamate oxaloacetate transaminase 1, soluble
chr7_+_24884809 0.57 ENSMUST00000156372.1
ENSMUST00000124035.1
ribosomal protein S19
chr14_+_13454010 0.57 ENSMUST00000112656.2
synaptoporin
chr17_-_57149633 0.55 ENSMUST00000019633.7
CD70 antigen
chr2_-_69206133 0.54 ENSMUST00000112320.1
SPC25, NDC80 kinetochore complex component, homolog (S. cerevisiae)
chr6_-_128891105 0.54 ENSMUST00000178918.1
ENSMUST00000160290.1
cDNA sequence BC035044
chr15_-_77927728 0.51 ENSMUST00000174468.1
ENSMUST00000174529.1
ENSMUST00000173631.1
thioredoxin 2
chr13_-_98815408 0.50 ENSMUST00000040340.8
ENSMUST00000099277.4
ENSMUST00000179563.1
ENSMUST00000109403.1
FCH domain only 2
chr16_-_94856682 0.50 ENSMUST00000165538.1
potassium inwardly-rectifying channel, subfamily J, member 6
chrX_+_6415736 0.48 ENSMUST00000143641.3
shroom family member 4
chr19_-_10974664 0.48 ENSMUST00000072748.6
membrane-spanning 4-domains, subfamily A, member 10
chr5_-_115194283 0.47 ENSMUST00000112113.1
calcium binding protein 1
chr17_+_12584183 0.46 ENSMUST00000046959.7
solute carrier family 22 (organic cation transporter), member 2
chr14_+_13453937 0.45 ENSMUST00000153954.1
synaptoporin
chr4_-_43030440 0.44 ENSMUST00000135660.1
stomatin (Epb7.2)-like 2
chrX_-_101734125 0.44 ENSMUST00000056614.6
chemokine (C-X-C motif) receptor 3
chr7_+_24884651 0.44 ENSMUST00000153451.2
ENSMUST00000108429.1
ribosomal protein S19
chr1_-_38664947 0.43 ENSMUST00000039827.7
ENSMUST00000027250.7
AF4/FMR2 family, member 3
chr7_+_18718075 0.43 ENSMUST00000108481.1
ENSMUST00000051973.8
pregnancy-specific glycoprotein 22
chr11_-_3527916 0.42 ENSMUST00000020718.4
smoothelin
chr6_-_136941887 0.42 ENSMUST00000111891.1
Rho, GDP dissociation inhibitor (GDI) beta
chr7_+_24884611 0.38 ENSMUST00000108428.1
ribosomal protein S19
chr17_-_45595842 0.38 ENSMUST00000164618.1
ENSMUST00000097317.3
ENSMUST00000170113.1
solute carrier family 29 (nucleoside transporters), member 1
chr8_-_93079965 0.36 ENSMUST00000109582.1
carboxylesterase 1B
chr10_+_57631981 0.36 ENSMUST00000095668.3
ENSMUST00000075992.5
protein kinase inhibitor beta, cAMP dependent, testis specific
chr1_+_171559186 0.36 ENSMUST00000004829.7
CD244 natural killer cell receptor 2B4
chr3_+_64081642 0.36 ENSMUST00000029406.4
vomeronasal 2, receptor 1
chr6_-_136941494 0.36 ENSMUST00000111892.1
Rho, GDP dissociation inhibitor (GDI) beta
chr2_-_17731035 0.36 ENSMUST00000028080.5
nebulette
chr14_+_47001336 0.36 ENSMUST00000125113.1
sterile alpha motif domain containing 4
chr4_-_9643638 0.36 ENSMUST00000108333.1
ENSMUST00000108334.1
ENSMUST00000108335.1
ENSMUST00000152526.1
ENSMUST00000103004.3
aspartate-beta-hydroxylase
chr4_+_139622842 0.35 ENSMUST00000039818.9
aldehyde dehydrogenase 4 family, member A1
chrX_-_73435332 0.34 ENSMUST00000033738.7
three prime repair exonuclease 2
chr1_+_60908993 0.34 ENSMUST00000027164.2
cytotoxic T-lymphocyte-associated protein 4
chr5_-_30073554 0.34 ENSMUST00000026846.6
thymidylate synthase
chr8_-_105851981 0.33 ENSMUST00000040776.4
centromere protein T
chr1_-_52232296 0.33 ENSMUST00000114512.1
glutaminase
chr9_-_100486788 0.33 ENSMUST00000098458.3
interleukin 20 receptor beta
chr16_-_11909398 0.33 ENSMUST00000127972.1
ENSMUST00000121750.1
ENSMUST00000096272.4
ENSMUST00000073371.6
calcineurin-like phosphoesterase domain containing 1
chr9_-_59486323 0.32 ENSMUST00000165322.1
ariadne ubiquitin-conjugating enzyme E2 binding protein homolog 1 (Drosophila)
chr19_-_47138280 0.32 ENSMUST00000140512.1
ENSMUST00000035822.1
calcium homeostasis modulator 2
chr14_-_78725089 0.32 ENSMUST00000074729.5
diacylglycerol kinase, eta
chr1_-_193130201 0.32 ENSMUST00000085555.1
digestive organ expansion factor homolog (zebrafish)
chr13_-_12520377 0.31 ENSMUST00000179308.1
EDAR (ectodysplasin-A receptor)-associated death domain
chr17_+_27685197 0.31 ENSMUST00000097360.2
protein kinase C and casein kinase substrate in neurons 1
chr7_+_47050628 0.31 ENSMUST00000010451.5
transmembrane protein 86A
chr17_+_24840108 0.31 ENSMUST00000164251.1
hydroxyacyl glutathione hydrolase
chr6_-_136941694 0.30 ENSMUST00000032344.5
Rho, GDP dissociation inhibitor (GDI) beta
chr1_+_6487231 0.30 ENSMUST00000140079.1
ENSMUST00000131494.1
suppression of tumorigenicity 18
chr3_-_132950043 0.29 ENSMUST00000117164.1
ENSMUST00000093971.4
ENSMUST00000042729.9
ENSMUST00000042744.9
ENSMUST00000117811.1
nephronectin
chr3_-_19265007 0.29 ENSMUST00000091314.4
phosphodiesterase 7A
chr8_-_22694061 0.29 ENSMUST00000131767.1
inhibitor of kappaB kinase beta
chr2_-_155074447 0.29 ENSMUST00000137242.1
ENSMUST00000054607.9
S-adenosylhomocysteine hydrolase
chr7_+_64392645 0.28 ENSMUST00000037205.8
methylmalonyl CoA epimerase
chr16_+_20651652 0.25 ENSMUST00000007212.8
proteasome (prosome, macropain) 26S subunit, non-ATPase, 2
chr9_-_106158109 0.24 ENSMUST00000159809.1
ENSMUST00000162562.1
ENSMUST00000036382.6
ENSMUST00000112543.2
glycerate kinase
chr9_-_26999491 0.24 ENSMUST00000060513.7
ENSMUST00000120367.1
acyl-Coenzyme A dehydrogenase family, member 8
chr6_+_128438757 0.24 ENSMUST00000144745.1
predicted gene 10069
chr11_+_118476824 0.24 ENSMUST00000135383.2
endo-beta-N-acetylglucosaminidase
chr11_+_52360824 0.24 ENSMUST00000102758.1
voltage-dependent anion channel 1
chr10_+_79822617 0.23 ENSMUST00000046833.4
mitotic spindle positioning
chr17_-_24696147 0.23 ENSMUST00000046839.8
growth factor, erv1 (S. cerevisiae)-like (augmenter of liver regeneration)
chr18_+_66458587 0.22 ENSMUST00000025399.7
phorbol-12-myristate-13-acetate-induced protein 1
chr8_-_70632419 0.22 ENSMUST00000110103.1
growth differentiation factor 15
chr16_+_20717665 0.22 ENSMUST00000021405.7
polymerase (RNA) II (DNA directed) polypeptide H
chr15_-_98004634 0.22 ENSMUST00000131560.1
ENSMUST00000088355.5
collagen, type II, alpha 1
chr8_-_93131271 0.21 ENSMUST00000034189.8
carboxylesterase 1C
chr2_-_155592567 0.21 ENSMUST00000155347.1
ENSMUST00000130881.1
ENSMUST00000079691.6
glutathione synthetase
chr3_-_146495115 0.20 ENSMUST00000093951.2
spermatogenesis associated 1
chr14_+_74735641 0.20 ENSMUST00000177283.1
esterase D/formylglutathione hydrolase
chr2_+_29890063 0.20 ENSMUST00000028128.6
outer dense fiber of sperm tails 2
chr15_+_83100201 0.19 ENSMUST00000078218.4
serine hydrolase-like
chr18_+_61639542 0.19 ENSMUST00000183083.1
ENSMUST00000183087.1
predicted gene, 20748
chr14_-_37110087 0.18 ENSMUST00000179488.1
RIKEN cDNA 2610528A11 gene
chr11_+_88204396 0.18 ENSMUST00000118784.1
ENSMUST00000139170.1
ENSMUST00000107915.3
ENSMUST00000144070.1
mitochondrial ribosomal protein S23
chr7_-_19458494 0.18 ENSMUST00000085715.5
MAP/microtubule affinity-regulating kinase 4
chr14_-_59365410 0.18 ENSMUST00000161031.1
ENSMUST00000160425.1
PHD finger protein 11D
chr11_-_93968242 0.18 ENSMUST00000107844.2
NME/NM23 nucleoside diphosphate kinase 1
chr16_+_57353093 0.18 ENSMUST00000159816.1
filamin A interacting protein 1-like
chr7_-_98309471 0.17 ENSMUST00000033020.7
alkaline ceramidase 3
chr11_+_73267388 0.17 ENSMUST00000049676.2
transient receptor potential cation channel, subfamily V, member 3
chr15_-_98004695 0.17 ENSMUST00000023123.8
collagen, type II, alpha 1
chr15_+_83100281 0.17 ENSMUST00000167389.1
ENSMUST00000166427.1
serine hydrolase-like
chr12_-_26415256 0.16 ENSMUST00000020971.6
ENSMUST00000062149.4
ring finger protein 144A
chr6_-_38837224 0.16 ENSMUST00000160962.1
homeodomain interacting protein kinase 2
chr6_+_39592569 0.16 ENSMUST00000135671.1
ENSMUST00000119379.1
NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2
chr6_+_71707561 0.16 ENSMUST00000121469.1
receptor accessory protein 1
chr2_-_136891363 0.15 ENSMUST00000028730.6
ENSMUST00000110089.2
McKusick-Kaufman syndrome
chr4_+_112232245 0.15 ENSMUST00000038455.5
ENSMUST00000170945.1
selection and upkeep of intraepithelial T cells 3
chr4_+_115057410 0.15 ENSMUST00000136946.1
T cell acute lymphocytic leukemia 1
chr9_+_78395777 0.15 ENSMUST00000113367.1
DEAD (Asp-Glu-Ala-Asp) box polypeptide 43
chr4_+_108459389 0.14 ENSMUST00000106673.1
ENSMUST00000043368.5
zinc finger, CCHC domain containing 11
chr14_-_59365465 0.14 ENSMUST00000095157.4
PHD finger protein 11D
chr1_-_22315792 0.14 ENSMUST00000164877.1
regulating synaptic membrane exocytosis 1
chr4_+_141213948 0.14 ENSMUST00000097813.2
REM2 and RAB-like small GTPase 1
chr12_+_76255209 0.14 ENSMUST00000021443.5
methylenetetrahydrofolate dehydrogenase (NADP+ dependent), methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthase
chr4_+_132351768 0.14 ENSMUST00000172202.1
predicted gene, 17300
chr14_-_54926784 0.14 ENSMUST00000022813.6
embryonal Fyn-associated substrate
chr9_+_38719024 0.14 ENSMUST00000129598.1
von Willebrand factor A domain containing 5A
chr19_-_10604258 0.13 ENSMUST00000037678.6
dihydroxyacetone kinase 2 homolog (yeast)
chr4_-_149099802 0.13 ENSMUST00000103217.4
peroxisomal biogenesis factor 14
chr8_-_84893887 0.13 ENSMUST00000003907.7
ENSMUST00000182458.1
ENSMUST00000109745.1
ENSMUST00000142748.1
glutaryl-Coenzyme A dehydrogenase
chr11_+_55469677 0.13 ENSMUST00000018727.3
GTPase activating protein (SH3 domain) binding protein 1
chr17_-_35066170 0.13 ENSMUST00000174190.1
ENSMUST00000097337.1
expressed sequence AU023871
chr6_-_116461024 0.12 ENSMUST00000164547.1
ENSMUST00000170186.1
arachidonate 5-lipoxygenase
chr9_+_65361049 0.12 ENSMUST00000147185.1
predicted gene 514
chr9_+_72438519 0.11 ENSMUST00000184604.1
meiosis-specific nuclear structural protein 1
chr5_+_92392585 0.11 ENSMUST00000126281.1
ADP-ribosyltransferase 3
chr2_-_150362708 0.11 ENSMUST00000051153.5
RIKEN cDNA 3300002I08 gene
chr17_+_3532554 0.10 ENSMUST00000168560.1
claudin 20
chr9_+_122117258 0.10 ENSMUST00000146832.1
ENSMUST00000139181.1
SNF related kinase
chr16_+_91391721 0.10 ENSMUST00000160764.1
predicted gene 21970
chr10_-_128409632 0.10 ENSMUST00000172348.1
ENSMUST00000166608.1
ENSMUST00000164199.1
ENSMUST00000171370.1
ENSMUST00000026439.7
nucleic acid binding protein 2
chr11_-_32267547 0.10 ENSMUST00000109389.2
ENSMUST00000129010.1
ENSMUST00000020530.5
nitrogen permease regulator-like 3
chr3_-_84305385 0.09 ENSMUST00000122849.1
ENSMUST00000132283.1
tripartite motif-containing 2
chr9_-_70141484 0.08 ENSMUST00000034749.8
family with sequence similarity 81, member A
chr10_+_21690845 0.08 ENSMUST00000071008.3
predicted gene 5420
chr14_-_20496780 0.08 ENSMUST00000022353.3
MSS51 mitochondrial translational activator
chr3_+_79885930 0.08 ENSMUST00000029567.8
family with sequence similarity 198, member B
chr9_+_108080436 0.08 ENSMUST00000035211.7
ENSMUST00000162886.1
macrophage stimulating 1 (hepatocyte growth factor-like)
chr6_-_85707858 0.07 ENSMUST00000179613.1
predicted gene 4477
chr5_-_66080971 0.07 ENSMUST00000127275.1
ENSMUST00000113724.1
RNA binding motif protein 47
chr3_+_90669063 0.07 ENSMUST00000069927.8
S100 calcium binding protein A8 (calgranulin A)
chr13_+_24376070 0.07 ENSMUST00000050859.5
cytidine monophospho-N-acetylneuraminic acid hydroxylase
chr2_-_163397946 0.07 ENSMUST00000017961.4
ENSMUST00000109425.2
junctophilin 2
chr3_+_96172327 0.06 ENSMUST00000076372.4
splicing factor 3b, subunit 4
chr10_+_94550852 0.06 ENSMUST00000148910.1
ENSMUST00000117460.1
transmembrane and coiled coil domains 3
chr1_-_173982842 0.06 ENSMUST00000000266.7
interferon activated gene 202B
chr14_-_49066368 0.06 ENSMUST00000161504.1
exocyst complex component 5
chr2_+_180078623 0.05 ENSMUST00000087563.6
mitochondrial ribosome associated GTPase 2
chr19_-_4793851 0.05 ENSMUST00000178615.1
ENSMUST00000179189.1
ENSMUST00000164376.2
ENSMUST00000164209.2
ENSMUST00000180248.1
RNA binding motif protein 4
chr7_-_64872993 0.04 ENSMUST00000094331.2
necdin-like 2
chr5_+_24100578 0.04 ENSMUST00000030841.5
ENSMUST00000163409.1
kelch-like 7
chr6_+_127446819 0.04 ENSMUST00000112191.1
poly (ADP-ribose) polymerase family, member 11
chr1_+_51289106 0.03 ENSMUST00000051572.6
serum deprivation response
chr17_-_34862122 0.02 ENSMUST00000154526.1
complement factor B
chr10_+_80622677 0.02 ENSMUST00000079773.6
casein kinase 1, gamma 2
chr11_+_71516515 0.01 ENSMUST00000151841.1
RIKEN cDNA 9230020A06 gene
chr1_-_161131428 0.01 ENSMUST00000111611.1
kelch-like 20
chr8_-_9977650 0.01 ENSMUST00000170033.1
ligase IV, DNA, ATP-dependent
chr8_+_9977707 0.01 ENSMUST00000139793.1
ENSMUST00000048216.5
abhydrolase domain containing 13
chr11_-_116077606 0.01 ENSMUST00000106450.1
unc-13 homolog D (C. elegans)
chr9_-_76567092 0.00 ENSMUST00000183437.1
family with sequence similarity 83, member B
chr7_-_92637079 0.00 ENSMUST00000056106.7
ENSMUST00000118157.1
ankyrin repeat domain 42
chr7_-_120095177 0.00 ENSMUST00000046993.3
dynein, axonemal, heavy chain 3

Network of associatons between targets according to the STRING database.

First level regulatory network of Trp53

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
2.0 6.1 GO:0072382 minus-end-directed vesicle transport along microtubule(GO:0072382)
0.3 1.4 GO:0060265 positive regulation of respiratory burst involved in inflammatory response(GO:0060265)
0.3 1.4 GO:1900740 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.3 2.6 GO:0071493 cellular response to UV-B(GO:0071493)
0.2 0.7 GO:0032877 positive regulation of DNA endoreduplication(GO:0032877)
0.2 1.0 GO:0061110 dense core granule biogenesis(GO:0061110)
0.2 0.6 GO:0006533 fumarate metabolic process(GO:0006106) glycerol biosynthetic process(GO:0006114) aspartate biosynthetic process(GO:0006532) aspartate catabolic process(GO:0006533)
0.2 1.2 GO:0007000 nucleolus organization(GO:0007000)
0.2 0.7 GO:0072108 positive regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis(GO:0072108)
0.2 0.6 GO:0042222 interleukin-1 biosynthetic process(GO:0042222)
0.1 0.4 GO:0090297 positive regulation of mitochondrial DNA replication(GO:0090297) regulation of cardiolipin metabolic process(GO:1900208) positive regulation of cardiolipin metabolic process(GO:1900210) stress-induced mitochondrial fusion(GO:1990046)
0.1 1.1 GO:1901164 negative regulation of trophoblast cell migration(GO:1901164)
0.1 0.4 GO:0071663 granzyme B production(GO:0071613) regulation of granzyme B production(GO:0071661) positive regulation of granzyme B production(GO:0071663)
0.1 0.8 GO:0014045 establishment of endothelial blood-brain barrier(GO:0014045)
0.1 0.4 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.1 0.4 GO:0010133 proline catabolic process to glutamate(GO:0010133)
0.1 0.3 GO:0002884 type IV hypersensitivity(GO:0001806) negative regulation of hypersensitivity(GO:0002884)
0.1 2.2 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.1 0.3 GO:0046073 dTMP biosynthetic process(GO:0006231) dTMP metabolic process(GO:0046073)
0.1 0.3 GO:0061152 trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.1 0.3 GO:2000721 positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721)
0.1 0.3 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.1 0.3 GO:0002439 chronic inflammatory response to antigenic stimulus(GO:0002439)
0.1 0.3 GO:0045590 negative regulation of regulatory T cell differentiation(GO:0045590)
0.1 1.2 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.1 4.3 GO:0007019 microtubule depolymerization(GO:0007019)
0.1 0.3 GO:0006543 glutamine catabolic process(GO:0006543)
0.1 0.4 GO:0015862 uridine transport(GO:0015862)
0.0 0.2 GO:0046294 formaldehyde catabolic process(GO:0046294)
0.0 0.9 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.1 GO:0016561 protein import into peroxisome matrix, translocation(GO:0016561)
0.0 0.1 GO:0046949 fatty-acyl-CoA biosynthetic process(GO:0046949)
0.0 0.7 GO:0007096 regulation of exit from mitosis(GO:0007096) positive regulation of meiotic nuclear division(GO:0045836)
0.0 0.4 GO:0060272 embryonic skeletal joint morphogenesis(GO:0060272)
0.0 0.2 GO:0038108 negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108)
0.0 0.5 GO:0015697 quaternary ammonium group transport(GO:0015697)
0.0 0.1 GO:0010808 positive regulation of synaptic vesicle priming(GO:0010808)
0.0 0.4 GO:1900118 negative regulation of execution phase of apoptosis(GO:1900118)
0.0 0.7 GO:0046641 positive regulation of alpha-beta T cell proliferation(GO:0046641)
0.0 1.6 GO:0014047 glutamate secretion(GO:0014047)
0.0 0.3 GO:0061727 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.0 0.1 GO:0006547 histidine metabolic process(GO:0006547)
0.0 0.3 GO:0034501 protein localization to kinetochore(GO:0034501)
0.0 0.4 GO:0019236 response to pheromone(GO:0019236)
0.0 0.3 GO:0035337 fatty-acyl-CoA metabolic process(GO:0035337)
0.0 0.5 GO:0018904 glycerol ether metabolic process(GO:0006662) ether metabolic process(GO:0018904)
0.0 0.3 GO:2001269 positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway(GO:2001269)
0.0 0.1 GO:0070488 neutrophil aggregation(GO:0070488)
0.0 0.3 GO:0046339 diacylglycerol metabolic process(GO:0046339)
0.0 0.9 GO:0060441 epithelial tube branching involved in lung morphogenesis(GO:0060441)
0.0 0.2 GO:0097421 liver regeneration(GO:0097421)
0.0 0.9 GO:0006418 tRNA aminoacylation for protein translation(GO:0006418)
0.0 0.2 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.0 0.5 GO:0048268 clathrin coat assembly(GO:0048268)
0.0 0.1 GO:0002540 leukotriene production involved in inflammatory response(GO:0002540)
0.0 0.2 GO:0006517 protein deglycosylation(GO:0006517)
0.0 0.1 GO:0046381 CMP-N-acetylneuraminate metabolic process(GO:0046381)
0.0 0.2 GO:0006228 UTP biosynthetic process(GO:0006228)
0.0 0.1 GO:0010587 miRNA catabolic process(GO:0010587)
0.0 0.8 GO:0051220 cytoplasmic sequestering of protein(GO:0051220)
0.0 0.2 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)
0.0 0.1 GO:0060316 positive regulation of ryanodine-sensitive calcium-release channel activity(GO:0060316)
0.0 0.4 GO:0000289 nuclear-transcribed mRNA poly(A) tail shortening(GO:0000289)
0.0 0.2 GO:0046512 sphingosine biosynthetic process(GO:0046512) sphingoid biosynthetic process(GO:0046520)
0.0 1.3 GO:0007052 mitotic spindle organization(GO:0007052)
0.0 1.6 GO:0051028 mRNA transport(GO:0051028)
0.0 0.1 GO:2000479 regulation of cAMP-dependent protein kinase activity(GO:2000479)
0.0 0.4 GO:0010107 potassium ion import(GO:0010107)
0.0 0.3 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 0.2 GO:1901741 positive regulation of myoblast fusion(GO:1901741)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.8 GO:0070557 PCNA-p21 complex(GO:0070557)
0.3 6.1 GO:0031616 spindle pole centrosome(GO:0031616)
0.3 1.4 GO:0000235 astral microtubule(GO:0000235)
0.2 1.3 GO:0031262 Ndc80 complex(GO:0031262)
0.2 0.5 GO:0098835 presynaptic endocytic zone(GO:0098833) presynaptic endocytic zone membrane(GO:0098835)
0.1 1.4 GO:0005736 DNA-directed RNA polymerase I complex(GO:0005736)
0.1 1.0 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.1 1.0 GO:0097539 ciliary transition fiber(GO:0097539)
0.1 4.6 GO:0005881 cytoplasmic microtubule(GO:0005881)
0.1 0.8 GO:0046581 intercellular canaliculus(GO:0046581)
0.1 0.4 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.1 0.3 GO:0030485 smooth muscle contractile fiber(GO:0030485)
0.0 2.3 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 1.0 GO:0030285 integral component of synaptic vesicle membrane(GO:0030285) intrinsic component of synaptic vesicle membrane(GO:0098563)
0.0 0.3 GO:0097413 Lewy body(GO:0097413)
0.0 0.2 GO:1902636 kinociliary basal body(GO:1902636)
0.0 0.1 GO:1990429 Pex17p-Pex14p docking complex(GO:1990415) peroxisomal importomer complex(GO:1990429)
0.0 0.4 GO:0098643 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.1 GO:0098831 presynaptic active zone cytoplasmic component(GO:0098831)
0.0 0.1 GO:0070876 SOSS complex(GO:0070876)
0.0 1.2 GO:0005871 kinesin complex(GO:0005871)
0.0 0.1 GO:1990130 Iml1 complex(GO:1990130)
0.0 1.6 GO:0042734 presynaptic membrane(GO:0042734)
0.0 0.3 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.2 GO:0031597 proteasome regulatory particle, base subcomplex(GO:0008540) cytosolic proteasome complex(GO:0031597)
0.0 1.6 GO:0005643 nuclear pore(GO:0005643)
0.0 0.8 GO:0098636 protein complex involved in cell adhesion(GO:0098636)
0.0 0.5 GO:0016460 myosin II complex(GO:0016460)
0.0 0.4 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.2 GO:0046930 pore complex(GO:0046930)
0.0 0.3 GO:0030137 COPI-coated vesicle(GO:0030137)
0.0 0.2 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 0.5 GO:0032809 neuronal cell body membrane(GO:0032809)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 2.8 GO:0019912 cyclin-dependent protein kinase activating kinase activity(GO:0019912)
0.2 6.1 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.2 0.6 GO:0080130 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069) L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.2 1.6 GO:0001640 adenylate cyclase inhibiting G-protein coupled glutamate receptor activity(GO:0001640)
0.2 0.7 GO:0005146 leukemia inhibitory factor receptor binding(GO:0005146)
0.2 0.5 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.2 0.5 GO:0005333 norepinephrine transmembrane transporter activity(GO:0005333)
0.1 1.1 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.1 0.8 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.1 0.3 GO:0042015 interleukin-20 binding(GO:0042015)
0.1 0.9 GO:0008494 translation activator activity(GO:0008494)
0.1 1.4 GO:0001054 RNA polymerase I activity(GO:0001054)
0.1 0.5 GO:0015467 G-protein activated inward rectifier potassium channel activity(GO:0015467)
0.1 0.3 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.1 0.2 GO:0018738 S-formylglutathione hydrolase activity(GO:0018738)
0.1 0.3 GO:0008384 IkappaB kinase activity(GO:0008384)
0.1 0.2 GO:0016971 flavin-linked sulfhydryl oxidase activity(GO:0016971)
0.1 1.2 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.1 0.4 GO:1901612 cardiolipin binding(GO:1901612)
0.1 0.3 GO:0004359 glutaminase activity(GO:0004359)
0.1 0.4 GO:0042289 MHC class II protein binding(GO:0042289)
0.1 0.4 GO:0045545 syndecan binding(GO:0045545)
0.0 0.3 GO:0019958 C-X-C chemokine binding(GO:0019958)
0.0 0.1 GO:0004487 methylenetetrahydrofolate dehydrogenase (NAD+) activity(GO:0004487)
0.0 0.3 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 1.4 GO:0017134 fibroblast growth factor binding(GO:0017134)
0.0 0.3 GO:0034511 U3 snoRNA binding(GO:0034511)
0.0 2.6 GO:0003777 microtubule motor activity(GO:0003777)
0.0 0.2 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.3 GO:0004416 hydroxyacylglutathione hydrolase activity(GO:0004416)
0.0 0.2 GO:0015288 porin activity(GO:0015288)
0.0 0.2 GO:0031849 olfactory receptor binding(GO:0031849)
0.0 0.1 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.0 0.3 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 0.7 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.1 GO:0004051 arachidonate 5-lipoxygenase activity(GO:0004051)
0.0 0.1 GO:0030338 CMP-N-acetylneuraminate monooxygenase activity(GO:0030338)
0.0 0.3 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.4 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.0 0.4 GO:0016646 oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor(GO:0016646)
0.0 0.9 GO:0016876 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.0 0.2 GO:0046790 virion binding(GO:0046790)
0.0 0.1 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.0 0.4 GO:0042288 MHC class I protein binding(GO:0042288)
0.0 0.1 GO:0004920 interleukin-10 receptor activity(GO:0004920)
0.0 0.2 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.4 GO:0030371 translation repressor activity(GO:0030371)
0.0 0.8 GO:0032813 tumor necrosis factor receptor superfamily binding(GO:0032813)
0.0 0.3 GO:0016854 racemase and epimerase activity(GO:0016854)
0.0 0.4 GO:0005337 nucleoside transmembrane transporter activity(GO:0005337)
0.0 0.2 GO:0016594 glycine binding(GO:0016594)
0.0 1.0 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 2.8 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1 1.2 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta
0.0 5.3 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors
0.0 0.7 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 1.1 PID CASPASE PATHWAY Caspase cascade in apoptosis
0.0 1.1 PID E2F PATHWAY E2F transcription factor network
0.0 0.4 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 6.1 REACTOME KINESINS Genes involved in Kinesins
0.1 2.8 REACTOME AKT PHOSPHORYLATES TARGETS IN THE CYTOSOL Genes involved in AKT phosphorylates targets in the cytosol
0.1 1.6 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.1 1.4 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.1 0.5 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.1 1.4 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 1.6 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0 1.1 REACTOME CTLA4 INHIBITORY SIGNALING Genes involved in CTLA4 inhibitory signaling
0.0 0.9 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 0.6 REACTOME METABOLISM OF POLYAMINES Genes involved in Metabolism of polyamines
0.0 1.4 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.6 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.3 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.0 0.5 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.3 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 1.6 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.3 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.3 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.2 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.5 REACTOME INHIBITION OF VOLTAGE GATED CA2 CHANNELS VIA GBETA GAMMA SUBUNITS Genes involved in Inhibition of voltage gated Ca2+ channels via Gbeta/gamma subunits