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2D miR_HR1_12

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Results for Nfatc1

Z-value: 0.82

Motif logo

Transcription factors associated with Nfatc1

Gene Symbol Gene ID Gene Info
ENSMUSG00000033016.9 nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Nfatc1mm10_v2_chr18_-_80713062_807130800.313.2e-01Click!

Activity profile of Nfatc1 motif

Sorted Z-values of Nfatc1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr5_-_88527841 1.47 ENSMUST00000087033.3
immunoglobulin joining chain
chr11_-_70656467 0.83 ENSMUST00000131642.1
predicted gene 12319
chr14_-_16575456 0.75 ENSMUST00000063750.6
retinoic acid receptor, beta
chr9_-_44526397 0.72 ENSMUST00000062215.7
chemokine (C-X-C motif) receptor 5
chr1_+_60908993 0.65 ENSMUST00000027164.2
cytotoxic T-lymphocyte-associated protein 4
chr1_+_150100093 0.64 ENSMUST00000035065.7
prostaglandin-endoperoxide synthase 2
chr1_-_170927567 0.64 ENSMUST00000046322.7
ENSMUST00000159171.1
Fc receptor-like A
chr1_+_34005872 0.63 ENSMUST00000182296.1
dystonin
chr4_-_44710408 0.61 ENSMUST00000134968.2
ENSMUST00000173821.1
ENSMUST00000174319.1
ENSMUST00000173733.1
ENSMUST00000172866.1
ENSMUST00000165417.2
ENSMUST00000107825.2
ENSMUST00000102932.3
ENSMUST00000107827.2
ENSMUST00000107826.2
paired box gene 5
chr8_-_69373914 0.60 ENSMUST00000095282.1
predicted gene 10311
chr2_+_74704615 0.53 ENSMUST00000151380.1
homeobox D8
chr9_+_7692086 0.51 ENSMUST00000018767.7
matrix metallopeptidase 7
chr1_+_134037490 0.51 ENSMUST00000162779.1
fibromodulin
chr15_+_78926720 0.50 ENSMUST00000089377.5
lectin, galactose binding, soluble 1
chr18_+_36559972 0.46 ENSMUST00000134146.1
ankyrin repeat and KH domain containing 1
chr16_-_3718105 0.42 ENSMUST00000023180.7
ENSMUST00000100222.2
Mediterranean fever
chr6_-_59426279 0.41 ENSMUST00000051065.4
GPRIN family member 3
chr10_-_19014549 0.41 ENSMUST00000146388.1
tumor necrosis factor, alpha-induced protein 3
chr1_-_120505084 0.40 ENSMUST00000027639.1
macrophage receptor with collagenous structure
chrX_-_9469288 0.39 ENSMUST00000015484.3
cytochrome b-245, beta polypeptide
chr13_-_99900645 0.38 ENSMUST00000022150.6
CART prepropeptide
chr15_-_72546279 0.37 ENSMUST00000044624.6
potassium channel, subfamily K, member 9
chr1_-_180193653 0.37 ENSMUST00000159914.1
aarF domain containing kinase 3
chr6_+_40110251 0.37 ENSMUST00000061740.7
transmembrane protein 178B
chr1_-_170927540 0.36 ENSMUST00000162136.1
ENSMUST00000162887.1
Fc receptor-like A
chr6_-_124911636 0.36 ENSMUST00000032217.1
lymphocyte-activation gene 3
chr8_-_36953139 0.35 ENSMUST00000179501.1
deleted in liver cancer 1
chr4_+_134864536 0.33 ENSMUST00000030627.7
Rh blood group, D antigen
chr1_-_156204998 0.32 ENSMUST00000015628.3
family with sequence similarity 163, member A
chr15_+_4375462 0.31 ENSMUST00000061925.4
phosphatidylinositol-specific phospholipase C, X domain containing 3
chr5_+_138229822 0.31 ENSMUST00000159798.1
ENSMUST00000159964.1
neurexophilin and PC-esterase domain family, member 5
chr1_+_170214826 0.30 ENSMUST00000159201.1
ENSMUST00000055830.1
RIKEN cDNA 4930500M09 gene
chr8_+_45627946 0.30 ENSMUST00000145458.1
sorbin and SH3 domain containing 2
chr1_-_127840290 0.29 ENSMUST00000061512.2
mitogen-activated protein kinase kinase kinase 19
chr11_+_95842668 0.29 ENSMUST00000100532.3
ENSMUST00000036088.4
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2
chr12_+_33314277 0.29 ENSMUST00000133549.1
ataxin 7-like 1
chr9_-_58158498 0.28 ENSMUST00000168864.2
immunoglobulin superfamily containing leucine-rich repeat
chr11_-_100261021 0.28 ENSMUST00000080893.6
keratin 17
chr14_+_61138445 0.28 ENSMUST00000089394.3
ENSMUST00000119509.1
sacsin
chr15_-_66801577 0.28 ENSMUST00000168589.1
src-like adaptor
chrX_-_12128386 0.28 ENSMUST00000145872.1
BCL6 interacting corepressor
chrX_-_105929206 0.28 ENSMUST00000134381.1
ENSMUST00000154866.1
alpha thalassemia/mental retardation syndrome X-linked homolog (human)
chr6_-_82774448 0.28 ENSMUST00000000642.4
hexokinase 2
chr11_+_118433826 0.27 ENSMUST00000106286.1
C1q and tumor necrosis factor related protein 1
chr7_+_134670667 0.27 ENSMUST00000084488.4
dedicator of cytokinesis 1
chr15_+_89568322 0.27 ENSMUST00000023295.2
acrosin prepropeptide
chr7_+_75643223 0.26 ENSMUST00000137959.1
A kinase (PRKA) anchor protein 13
chr2_-_113758638 0.26 ENSMUST00000099575.3
gremlin 1
chrX_+_107088452 0.26 ENSMUST00000150494.1
purinergic receptor P2Y, G-protein coupled 10
chr2_+_30237680 0.26 ENSMUST00000113654.1
ENSMUST00000095078.2
leucine rich repeat containing 8A
chrX_+_73483602 0.26 ENSMUST00000033741.8
ENSMUST00000169489.1
biglycan
chr12_-_101819048 0.26 ENSMUST00000021603.8
fibulin 5
chr15_+_6579841 0.25 ENSMUST00000090461.5
FYN binding protein
chr8_+_34115030 0.25 ENSMUST00000095345.3
membrane bound O-acyltransferase domain containing 4
chr17_-_87282793 0.25 ENSMUST00000146560.2
RIKEN cDNA 4833418N02 gene
chr6_-_31218421 0.25 ENSMUST00000115107.1
cDNA sequence AB041803
chr4_-_82505707 0.24 ENSMUST00000107248.1
ENSMUST00000107247.1
nuclear factor I/B
chr4_-_12087912 0.24 ENSMUST00000050686.3
transmembrane protein 67
chr18_+_37484955 0.24 ENSMUST00000053856.4
protocadherin beta 17
chr19_+_22692613 0.23 ENSMUST00000099564.2
ENSMUST00000099566.3
transient receptor potential cation channel, subfamily M, member 3
chr14_-_59341325 0.23 ENSMUST00000166121.2
PHD finger protein 11B
chr6_+_48739039 0.23 ENSMUST00000054368.4
ENSMUST00000140054.1
GTPase, IMAP family member 1
chr10_+_76562270 0.23 ENSMUST00000009259.4
ENSMUST00000105414.1
spermatogenesis and centriole associated 1 like
chr12_-_103443653 0.23 ENSMUST00000055071.8
interferon, alpha-inducible protein 27 like 2A
chr12_-_99393010 0.22 ENSMUST00000177451.1
forkhead box N3
chrX_-_105929333 0.22 ENSMUST00000134507.1
ENSMUST00000137453.1
ENSMUST00000150914.1
alpha thalassemia/mental retardation syndrome X-linked homolog (human)
chr16_+_23429133 0.22 ENSMUST00000038730.6
receptor transporter protein 1
chr8_+_106510853 0.21 ENSMUST00000080797.6
cadherin 3
chr13_-_23761223 0.21 ENSMUST00000102964.2
histone cluster 1, H4a
chr12_+_36090379 0.21 ENSMUST00000071825.5
predicted gene 5434
chr7_+_30423266 0.21 ENSMUST00000046177.8
nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, delta
chr7_+_46847128 0.20 ENSMUST00000005051.4
lactate dehydrogenase A
chr4_-_116405986 0.20 ENSMUST00000123072.1
ENSMUST00000144281.1
microtubule associated serine/threonine kinase 2
chr11_-_83530505 0.20 ENSMUST00000035938.2
chemokine (C-C motif) ligand 5
chr10_-_27616895 0.19 ENSMUST00000092639.5
laminin, alpha 2
chr2_+_35282380 0.19 ENSMUST00000028239.6
gelsolin
chr19_+_11895999 0.19 ENSMUST00000072784.2
olfactory receptor 1420
chr10_-_87008015 0.19 ENSMUST00000035288.8
stabilin 2
chr4_-_42168603 0.19 ENSMUST00000098121.3
predicted gene 13305
chr10_+_40629987 0.18 ENSMUST00000019977.7
D-aspartate oxidase
chr2_+_155751117 0.18 ENSMUST00000029140.5
ENSMUST00000132608.1
protein C receptor, endothelial
chr13_-_98890974 0.18 ENSMUST00000179301.1
ENSMUST00000179271.1
transportin 1
chr7_-_127137807 0.18 ENSMUST00000049931.5
sialophorin
chr14_+_51984857 0.18 ENSMUST00000100639.4
ENSMUST00000182909.1
ENSMUST00000182760.1
ENSMUST00000182061.1
ENSMUST00000182193.1
Rho guanine nucleotide exchange factor (GEF) 40
chr1_+_4808237 0.18 ENSMUST00000131119.1
lysophospholipase 1
chr18_-_13972617 0.17 ENSMUST00000025288.7
zinc finger protein 521
chr9_-_75597643 0.17 ENSMUST00000164100.1
tropomodulin 2
chr17_-_87282771 0.17 ENSMUST00000161759.1
RIKEN cDNA 4833418N02 gene
chr5_+_104508338 0.17 ENSMUST00000096452.4
cDNA sequence BC005561
chr3_-_152266320 0.17 ENSMUST00000046045.8
nexilin
chr10_+_125966214 0.17 ENSMUST00000074807.6
leucine-rich repeats and immunoglobulin-like domains 3
chrX_+_143664365 0.17 ENSMUST00000126592.1
ENSMUST00000156449.1
ENSMUST00000155215.1
ENSMUST00000112865.1
p21 protein (Cdc42/Rac)-activated kinase 3
chr11_+_95842283 0.17 ENSMUST00000107714.2
ENSMUST00000107711.1
guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 2
chr14_+_48446128 0.16 ENSMUST00000124720.1
transmembrane protein 260
chr4_-_129558355 0.16 ENSMUST00000167288.1
ENSMUST00000134336.1
lymphocyte protein tyrosine kinase
chrX_-_48454152 0.16 ENSMUST00000114958.1
E74-like factor 4 (ets domain transcription factor)
chr10_-_62507737 0.16 ENSMUST00000020271.6
serglycin
chr8_+_105427634 0.16 ENSMUST00000067305.6
leucine rich repeat containing 36
chr10_-_28986280 0.16 ENSMUST00000152363.1
ENSMUST00000015663.6
RIKEN cDNA 2310057J18 gene
chr11_+_99047311 0.16 ENSMUST00000140772.1
insulin-like growth factor binding protein 4
chr5_+_44966583 0.16 ENSMUST00000079389.5
RIKEN cDNA 4930431F12 gene
chr10_+_127048235 0.16 ENSMUST00000165764.1
cytochrome P450, family 27, subfamily b, polypeptide 1
chr17_+_34153072 0.16 ENSMUST00000114232.2
histocompatibility 2, class II, locus Mb1
chr19_-_37176055 0.15 ENSMUST00000142973.1
ENSMUST00000154376.1
cytoplasmic polyadenylation element binding protein 3
chr4_-_129558387 0.15 ENSMUST00000067240.4
lymphocyte protein tyrosine kinase
chr5_-_51567717 0.15 ENSMUST00000127135.1
ENSMUST00000151104.1
peroxisome proliferative activated receptor, gamma, coactivator 1 alpha
chr7_+_43562256 0.15 ENSMUST00000107972.1
zinc finger protein 658
chrX_+_103422010 0.15 ENSMUST00000182089.1
predicted gene, 26992
chr19_-_5845471 0.15 ENSMUST00000174287.1
ENSMUST00000173672.1
nuclear paraspeckle assembly transcript 1 (non-protein coding)
chr8_+_45627709 0.15 ENSMUST00000134321.1
ENSMUST00000135336.1
sorbin and SH3 domain containing 2
chr7_+_110773658 0.15 ENSMUST00000143786.1
adenosine monophosphate deaminase 3
chr1_-_60043087 0.15 ENSMUST00000027172.6
islet cell autoantigen 1-like
chr15_+_98708187 0.15 ENSMUST00000003444.4
coiled-coil domain containing 65
chr11_-_79530569 0.15 ENSMUST00000103236.3
ENSMUST00000170799.1
ENSMUST00000170422.2
ecotropic viral integration site 2a
ecotropic viral integration site 2b
chr7_+_110774240 0.15 ENSMUST00000147587.1
adenosine monophosphate deaminase 3
chr16_-_50330987 0.15 ENSMUST00000114488.1
bobby sox homolog (Drosophila)
chr11_+_82045705 0.15 ENSMUST00000021011.2
chemokine (C-C motif) ligand 7
chr9_+_89199209 0.15 ENSMUST00000068569.4
B cell leukemia/lymphoma 2 related protein A1b
chr11_-_11627824 0.14 ENSMUST00000081896.4
RIKEN cDNA 4930512M02 gene
chr18_+_36560581 0.14 ENSMUST00000155329.2
ankyrin repeat and KH domain containing 1
chr6_+_134035953 0.14 ENSMUST00000164648.1
ets variant gene 6 (TEL oncogene)
chr8_+_66386292 0.14 ENSMUST00000039540.5
ENSMUST00000110253.2
membrane-associated ring finger (C3HC4) 1
chr3_+_146150174 0.14 ENSMUST00000098524.4
mucolipin 2
chr1_-_195092242 0.14 ENSMUST00000162650.1
ENSMUST00000160817.1
ENSMUST00000162614.1
ENSMUST00000016637.6
CD46 antigen, complement regulatory protein
chrX_+_139210031 0.13 ENSMUST00000113043.1
ENSMUST00000169886.1
ENSMUST00000113045.2
melanoma associated antigen (mutated) 1-like 1
chr1_+_87264345 0.13 ENSMUST00000118687.1
ENSMUST00000027472.6
EF hand domain containing 1
chr9_+_124102110 0.13 ENSMUST00000168841.1
ENSMUST00000055918.6
chemokine (C-C motif) receptor 2
chr9_+_100643755 0.13 ENSMUST00000133388.1
stromal antigen 1
chrX_+_164162167 0.13 ENSMUST00000131543.1
angiotensin I converting enzyme (peptidyl-dipeptidase A) 2
chr7_+_81523531 0.13 ENSMUST00000181903.1
RIKEN cDNA 2900076A07 gene
chr16_-_13986855 0.13 ENSMUST00000117803.1
interferon induced transmembrane protein 7
chr2_-_121271315 0.13 ENSMUST00000131245.1
transformation related protein 53 binding protein 1
chrX_+_143664290 0.13 ENSMUST00000112868.1
p21 protein (Cdc42/Rac)-activated kinase 3
chrX_-_12128350 0.13 ENSMUST00000123004.1
BCL6 interacting corepressor
chr12_+_58211772 0.13 ENSMUST00000110671.2
ENSMUST00000044299.2
somatostatin receptor 1
chr13_-_67637776 0.12 ENSMUST00000012314.8
RIKEN cDNA A530054K11 gene
chrX_+_47912387 0.12 ENSMUST00000001202.8
ENSMUST00000115020.1
oculocerebrorenal syndrome of Lowe
chr18_+_37020097 0.12 ENSMUST00000047614.1
protocadherin alpha 2
chr10_+_112172540 0.12 ENSMUST00000132994.1
calcyphosphine 2
chrX_+_163908982 0.12 ENSMUST00000069041.8
adaptor-related protein complex 1, sigma 2 subunit
chr2_+_68104671 0.12 ENSMUST00000042456.3
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1
chr5_+_35893319 0.12 ENSMUST00000064571.4
actin filament associated protein 1
chr11_+_94044331 0.12 ENSMUST00000024979.8
sperm associated antigen 9
chr14_-_7994563 0.12 ENSMUST00000026315.7
deoxyribonuclease 1-like 3
chr4_-_94979063 0.11 ENSMUST00000075872.3
myb-like, SWIRM and MPN domains 1
chr2_-_77170534 0.11 ENSMUST00000111833.2
coiled-coil domain containing 141
chr8_-_69791170 0.11 ENSMUST00000131784.1
zinc finger protein 866
chr16_+_13986596 0.11 ENSMUST00000056521.5
ENSMUST00000118412.1
ENSMUST00000131608.1
RIKEN cDNA 2900011O08 gene
chr13_+_41655697 0.11 ENSMUST00000067176.8
predicted gene 5082
chr10_+_23960494 0.11 ENSMUST00000092660.1
trace amine-associated receptor 4
chr3_+_62419668 0.11 ENSMUST00000161057.1
Rho guanine nucleotide exchange factor (GEF) 26
chr13_+_67128219 0.11 ENSMUST00000052716.7
zinc finger protein 759
chr7_+_81523555 0.11 ENSMUST00000180385.1
ENSMUST00000180879.1
ENSMUST00000181164.1
ENSMUST00000181264.1
RIKEN cDNA 2900076A07 gene
chr2_+_127909058 0.11 ENSMUST00000110344.1
acyl-Coenzyme A oxidase-like
chrX_-_75382291 0.11 ENSMUST00000151772.1
ENSMUST00000033539.6
coagulation factor VIII
chr11_+_94044194 0.10 ENSMUST00000092777.4
ENSMUST00000075695.6
sperm associated antigen 9
chr9_+_92457369 0.10 ENSMUST00000034941.7
phospholipid scramblase 4
chr8_-_25038875 0.10 ENSMUST00000084031.4
HtrA serine peptidase 4
chr19_-_57118897 0.10 ENSMUST00000111526.1
actin-binding LIM protein 1
chr16_-_22161450 0.10 ENSMUST00000115379.1
insulin-like growth factor 2 mRNA binding protein 2
chr7_+_122965636 0.10 ENSMUST00000148880.1
retinoblastoma binding protein 6
chr4_+_102589687 0.10 ENSMUST00000097949.4
ENSMUST00000106901.1
phosphodiesterase 4B, cAMP specific
chr13_-_67683467 0.10 ENSMUST00000137496.2
ENSMUST00000175678.1
ENSMUST00000175821.1
ENSMUST00000125495.3
zinc finger protein 738
chr11_+_94044241 0.10 ENSMUST00000103168.3
sperm associated antigen 9
chr17_-_14934653 0.10 ENSMUST00000170386.1
WD repeat domain 27
chr9_-_20521375 0.10 ENSMUST00000068296.7
ENSMUST00000174462.1
zinc finger protein 266
chr17_+_87107621 0.10 ENSMUST00000041369.6
suppressor of cytokine signaling 5
chr11_+_96286623 0.10 ENSMUST00000049352.7
homeobox B7
chr2_-_140671440 0.10 ENSMUST00000099301.1
fibronectin leucine rich transmembrane protein 3
chr5_+_104202609 0.10 ENSMUST00000066708.5
dentin matrix protein 1
chr11_+_63132569 0.10 ENSMUST00000108701.1
peripheral myelin protein 22
chr9_-_20385090 0.10 ENSMUST00000068079.7
zinc finger protein 560
chr5_-_67099235 0.10 ENSMUST00000012664.8
paired-like homeobox 2b
chr6_+_108660772 0.10 ENSMUST00000163617.1
basic helix-loop-helix family, member e40
chrX_-_75382615 0.09 ENSMUST00000147349.1
coagulation factor VIII
chr11_+_75531690 0.09 ENSMUST00000149727.1
ENSMUST00000042561.7
ENSMUST00000108433.1
ENSMUST00000143035.1
solute carrier family 43, member 2
chr2_-_140671400 0.09 ENSMUST00000056760.3
fibronectin leucine rich transmembrane protein 3
chr18_+_74442551 0.09 ENSMUST00000121875.1
myosin VB
chr11_+_76904513 0.09 ENSMUST00000072633.3
transmembrane and immunoglobulin domain containing 1
chr3_+_121967822 0.09 ENSMUST00000137089.1
Rho GTPase activating protein 29
chr1_+_4807823 0.09 ENSMUST00000027036.4
ENSMUST00000119612.2
ENSMUST00000137887.1
ENSMUST00000115529.1
ENSMUST00000150971.1
lysophospholipase 1
chr3_-_106219477 0.09 ENSMUST00000082219.5
chitinase 3-like 4
chr9_-_96862903 0.08 ENSMUST00000121077.1
ENSMUST00000124923.1
acid phosphatase-like 2
chr1_-_95667555 0.08 ENSMUST00000043336.4
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
chr4_+_150087365 0.08 ENSMUST00000094451.3
G protein-coupled receptor 157
chr18_-_80713062 0.08 ENSMUST00000170905.1
ENSMUST00000078049.4
nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1
chr5_-_44099220 0.08 ENSMUST00000165909.1
prominin 1
chr3_-_116711820 0.08 ENSMUST00000153108.1
solute carrier family 35 (UDP-N-acetylglucosamine (UDP-GlcNAc) transporter), member 3
chrX_+_163909132 0.08 ENSMUST00000033734.7
ENSMUST00000112294.2
adaptor-related protein complex 1, sigma 2 subunit
chr14_+_84443553 0.08 ENSMUST00000071370.5
protocadherin 17
chr1_-_91459254 0.08 ENSMUST00000069620.8
period circadian clock 2
chr15_-_34356421 0.08 ENSMUST00000179647.1
RIKEN cDNA 9430069I07 gene
chr11_+_120361506 0.08 ENSMUST00000026445.2
fascin homolog 2, actin-bundling protein, retinal (Strongylocentrotus purpuratus)
chr14_-_21052120 0.08 ENSMUST00000130370.1
ENSMUST00000022371.3
adaptor-related protein complex 3, mu 1 subunit
chr11_-_31824463 0.08 ENSMUST00000129425.1
ENSMUST00000126265.1
RIKEN cDNA D630024D03 gene
chr7_+_30095150 0.08 ENSMUST00000130526.1
ENSMUST00000108200.1
zinc finger protein 260
chr8_+_10272572 0.08 ENSMUST00000042103.8
myosin XVI
chr6_+_149309391 0.08 ENSMUST00000130664.1
ENSMUST00000046689.6
RIKEN cDNA 2810474O19 gene
chr7_+_99535439 0.08 ENSMUST00000098266.2
ENSMUST00000179755.1
arrestin, beta 1
chr7_+_140218258 0.08 ENSMUST00000084460.6
CD163 molecule-like 1

Network of associatons between targets according to the STRING database.

First level regulatory network of Nfatc1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.4 GO:0071608 macrophage inflammatory protein-1 alpha production(GO:0071608)
0.2 0.5 GO:0002780 antimicrobial peptide biosynthetic process(GO:0002777) antibacterial peptide biosynthetic process(GO:0002780)
0.2 0.6 GO:1902219 positive regulation of fibroblast growth factor production(GO:0090271) negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902219)
0.1 0.6 GO:0035127 post-embryonic appendage morphogenesis(GO:0035120) post-embryonic limb morphogenesis(GO:0035127) post-embryonic forelimb morphogenesis(GO:0035128) telomeric repeat-containing RNA transcription(GO:0097393) telomeric repeat-containing RNA transcription from RNA pol II promoter(GO:0097394) regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901580) negative regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901581) positive regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901582)
0.1 0.7 GO:0045590 negative regulation of regulatory T cell differentiation(GO:0045590)
0.1 0.4 GO:0072573 regulation of granuloma formation(GO:0002631) negative regulation of granuloma formation(GO:0002632) regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429) tolerance induction to lipopolysaccharide(GO:0072573)
0.1 0.4 GO:0070093 negative regulation of glucagon secretion(GO:0070093)
0.1 0.8 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.1 0.4 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.1 0.3 GO:1900157 regulation of bone mineralization involved in bone maturation(GO:1900157)
0.1 0.5 GO:0002317 plasma cell differentiation(GO:0002317)
0.1 0.2 GO:0051794 negative regulation of hair follicle maturation(GO:0048817) regulation of catagen(GO:0051794)
0.1 0.2 GO:0003345 proepicardium cell migration involved in pericardium morphogenesis(GO:0003345)
0.1 0.2 GO:1903903 positive regulation of keratinocyte apoptotic process(GO:1902174) regulation of establishment of T cell polarity(GO:1903903)
0.1 0.2 GO:0006533 aspartate catabolic process(GO:0006533) D-amino acid catabolic process(GO:0019478)
0.1 0.2 GO:0001806 type IV hypersensitivity(GO:0001806) negative regulation of hypersensitivity(GO:0002884)
0.1 0.2 GO:0032474 otolith morphogenesis(GO:0032474)
0.1 0.3 GO:0035795 negative regulation of mitochondrial membrane permeability(GO:0035795) positive regulation of macromitophagy(GO:1901526) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925)
0.1 0.3 GO:0007341 penetration of zona pellucida(GO:0007341)
0.1 0.3 GO:0045085 negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.1 0.2 GO:1900248 cytoplasmic translational elongation(GO:0002182) regulation of cytoplasmic translational elongation(GO:1900247) negative regulation of cytoplasmic translational elongation(GO:1900248)
0.1 0.2 GO:0033634 positive regulation of cell-cell adhesion mediated by integrin(GO:0033634)
0.0 0.4 GO:0097411 hypoxia-inducible factor-1alpha signaling pathway(GO:0097411)
0.0 0.1 GO:0043380 regulation of memory T cell differentiation(GO:0043380)
0.0 0.3 GO:0002084 protein depalmitoylation(GO:0002084) negative regulation of Golgi to plasma membrane protein transport(GO:0042997) negative regulation of establishment of protein localization to plasma membrane(GO:0090005) macromolecule depalmitoylation(GO:0098734)
0.0 0.3 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.0 0.2 GO:0033370 protein localization to secretory granule(GO:0033366) protein localization to mast cell secretory granule(GO:0033367) protease localization to mast cell secretory granule(GO:0033368) maintenance of protein location in mast cell secretory granule(GO:0033370) T cell secretory granule organization(GO:0033371) maintenance of protease location in mast cell secretory granule(GO:0033373) protein localization to T cell secretory granule(GO:0033374) protease localization to T cell secretory granule(GO:0033375) maintenance of protein location in T cell secretory granule(GO:0033377) maintenance of protease location in T cell secretory granule(GO:0033379) granzyme B localization to T cell secretory granule(GO:0033380) maintenance of granzyme B location in T cell secretory granule(GO:0033382)
0.0 0.2 GO:0019244 fermentation(GO:0006113) lactate biosynthetic process from pyruvate(GO:0019244) glucose catabolic process to lactate(GO:0019659) glycolytic fermentation(GO:0019660) glucose catabolic process to lactate via pyruvate(GO:0019661)
0.0 0.2 GO:0007597 blood coagulation, intrinsic pathway(GO:0007597)
0.0 0.3 GO:2000860 positive regulation of mineralocorticoid secretion(GO:2000857) positive regulation of aldosterone secretion(GO:2000860)
0.0 0.2 GO:0010979 regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980)
0.0 0.2 GO:2000182 regulation of progesterone biosynthetic process(GO:2000182)
0.0 0.3 GO:0032264 IMP salvage(GO:0032264)
0.0 0.3 GO:0070472 regulation of uterine smooth muscle contraction(GO:0070472) positive regulation of uterine smooth muscle contraction(GO:0070474)
0.0 0.3 GO:0071883 activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.0 0.2 GO:0032224 positive regulation of synaptic transmission, cholinergic(GO:0032224)
0.0 0.1 GO:0003051 angiotensin-mediated drinking behavior(GO:0003051) aromatic amino acid transport(GO:0015801) tryptophan transport(GO:0015827)
0.0 0.2 GO:0070245 positive regulation of thymocyte apoptotic process(GO:0070245)
0.0 0.1 GO:0035522 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.0 0.1 GO:1903976 negative regulation of glial cell migration(GO:1903976)
0.0 0.1 GO:0060854 patterning of lymph vessels(GO:0060854)
0.0 0.1 GO:0072139 glomerular parietal epithelial cell differentiation(GO:0072139)
0.0 0.1 GO:0031554 regulation of DNA-templated transcription, termination(GO:0031554)
0.0 0.6 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 0.3 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.6 GO:0021670 lateral ventricle development(GO:0021670)
0.0 0.1 GO:0035565 regulation of pronephros size(GO:0035565) mesonephros morphogenesis(GO:0061206) mesonephric nephron development(GO:0061215) mesonephric nephron morphogenesis(GO:0061228) mesenchymal stem cell maintenance involved in mesonephric nephron morphogenesis(GO:0061235) regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:0061295) negative regulation of mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:0061296) mesenchymal cell apoptotic process involved in mesonephric nephron morphogenesis(GO:1901146)
0.0 0.3 GO:0051798 positive regulation of hair follicle development(GO:0051798)
0.0 0.1 GO:0032439 endosome localization(GO:0032439)
0.0 0.2 GO:0051694 pointed-end actin filament capping(GO:0051694)
0.0 0.3 GO:0030322 stabilization of membrane potential(GO:0030322)
0.0 0.1 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.0 0.3 GO:0015695 organic cation transport(GO:0015695)
0.0 0.3 GO:0019800 peptide cross-linking via chondroitin 4-sulfate glycosaminoglycan(GO:0019800)
0.0 0.1 GO:0033078 extrathymic T cell differentiation(GO:0033078)
0.0 0.1 GO:0046271 coumarin metabolic process(GO:0009804) phenylpropanoid catabolic process(GO:0046271)
0.0 0.1 GO:0048880 hindbrain tangential cell migration(GO:0021934) sensory system development(GO:0048880)
0.0 0.1 GO:0045629 negative regulation of T-helper 2 cell differentiation(GO:0045629)
0.0 0.1 GO:0001866 NK T cell proliferation(GO:0001866)
0.0 0.2 GO:0046606 negative regulation of centrosome duplication(GO:0010826) negative regulation of centrosome cycle(GO:0046606)
0.0 0.3 GO:0002329 pre-B cell differentiation(GO:0002329)
0.0 0.7 GO:0032467 positive regulation of cytokinesis(GO:0032467)
0.0 0.3 GO:1900119 positive regulation of execution phase of apoptosis(GO:1900119)
0.0 0.4 GO:0007194 negative regulation of adenylate cyclase activity(GO:0007194)
0.0 0.0 GO:0072190 ureter urothelium development(GO:0072190) ureter morphogenesis(GO:0072197)
0.0 0.1 GO:0015788 UDP-N-acetylglucosamine transport(GO:0015788)
0.0 0.1 GO:0070170 regulation of tooth mineralization(GO:0070170)
0.0 0.1 GO:0042699 follicle-stimulating hormone signaling pathway(GO:0042699)
0.0 0.2 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.2 GO:0048739 cardiac muscle fiber development(GO:0048739)
0.0 0.1 GO:0090094 canonical Wnt signaling pathway involved in positive regulation of wound healing(GO:0044330) lactic acid secretion(GO:0046722) metanephric cap development(GO:0072185) metanephric cap morphogenesis(GO:0072186) metanephric cap mesenchymal cell proliferation involved in metanephros development(GO:0090094) regulation of metanephric cap mesenchymal cell proliferation(GO:0090095) positive regulation of metanephric cap mesenchymal cell proliferation(GO:0090096)
0.0 0.1 GO:0044838 cell quiescence(GO:0044838)
0.0 0.1 GO:2000124 regulation of endocannabinoid signaling pathway(GO:2000124)
0.0 0.1 GO:0006121 mitochondrial electron transport, succinate to ubiquinone(GO:0006121)
0.0 0.4 GO:0010763 positive regulation of fibroblast migration(GO:0010763)
0.0 0.2 GO:0045075 interleukin-12 biosynthetic process(GO:0042090) regulation of interleukin-12 biosynthetic process(GO:0045075)
0.0 0.2 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.0 0.1 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.0 0.3 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.0 0.1 GO:0019375 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.1 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.1 GO:0045110 intermediate filament bundle assembly(GO:0045110)
0.0 0.0 GO:0002434 immune complex clearance(GO:0002434) immune complex clearance by monocytes and macrophages(GO:0002436) astrocyte chemotaxis(GO:0035700) regulation of immune complex clearance by monocytes and macrophages(GO:0090264) positive regulation of immune complex clearance by monocytes and macrophages(GO:0090265) negative regulation of eosinophil activation(GO:1902567) positive regulation of CD8-positive, alpha-beta T cell extravasation(GO:2000451) regulation of astrocyte chemotaxis(GO:2000458)
0.0 0.3 GO:0002495 antigen processing and presentation of peptide antigen via MHC class II(GO:0002495) antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002504)
0.0 0.0 GO:0033861 negative regulation of NAD(P)H oxidase activity(GO:0033861) neuron projection maintenance(GO:1990535)
0.0 0.1 GO:0032596 T cell antigen processing and presentation(GO:0002457) protein transport into membrane raft(GO:0032596)
0.0 0.2 GO:0045653 negative regulation of megakaryocyte differentiation(GO:0045653)
0.0 0.3 GO:0051482 positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway(GO:0051482)
0.0 0.2 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.0 0.0 GO:2000402 negative regulation of lymphocyte migration(GO:2000402)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:1990707 subtelomeric heterochromatin(GO:1990421) nuclear subtelomeric heterochromatin(GO:1990707)
0.1 0.6 GO:0031673 H zone(GO:0031673)
0.1 0.3 GO:0071953 elastic fiber(GO:0071953)
0.0 0.4 GO:0043020 NADPH oxidase complex(GO:0043020)
0.0 0.1 GO:0002079 inner acrosomal membrane(GO:0002079)
0.0 0.8 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.0 0.2 GO:0030478 actin cap(GO:0030478)
0.0 0.3 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.1 GO:0042382 paraspeckles(GO:0042382)
0.0 0.2 GO:0000445 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.1 GO:0071914 prominosome(GO:0071914)
0.0 0.2 GO:0042629 mast cell granule(GO:0042629)
0.0 0.2 GO:0001931 uropod(GO:0001931) cell trailing edge(GO:0031254)
0.0 0.2 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 0.3 GO:0000242 pericentriolar material(GO:0000242)
0.0 0.2 GO:0035686 sperm fibrous sheath(GO:0035686)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:0048030 disaccharide binding(GO:0048030)
0.1 0.6 GO:0042289 MHC class II protein binding(GO:0042289)
0.1 0.6 GO:0015616 DNA translocase activity(GO:0015616)
0.1 0.6 GO:0016494 C-X-C chemokine receptor activity(GO:0016494)
0.1 0.2 GO:0045159 myosin II binding(GO:0045159)
0.1 0.2 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.1 0.3 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.1 0.4 GO:0016175 superoxide-generating NADPH oxidase activity(GO:0016175)
0.1 0.3 GO:0042610 CD8 receptor binding(GO:0042610)
0.1 0.2 GO:0003884 D-amino-acid oxidase activity(GO:0003884)
0.1 0.4 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.1 0.2 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 0.2 GO:0031849 olfactory receptor binding(GO:0031849)
0.0 0.3 GO:0047623 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.0 0.1 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.0 0.8 GO:0003708 retinoic acid receptor activity(GO:0003708)
0.0 0.3 GO:0019158 fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0 0.6 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.1 GO:0031896 V2 vasopressin receptor binding(GO:0031896)
0.0 0.1 GO:0047275 glucosaminylgalactosylglucosylceramide beta-galactosyltransferase activity(GO:0047275)
0.0 0.1 GO:0001225 RNA polymerase II transcription coactivator binding(GO:0001225)
0.0 0.6 GO:0016702 oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702)
0.0 0.3 GO:0098599 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.2 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.0 0.1 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 0.1 GO:0004994 somatostatin receptor activity(GO:0004994)
0.0 0.1 GO:0098770 FBXO family protein binding(GO:0098770)
0.0 0.3 GO:0022841 potassium ion leak channel activity(GO:0022841)
0.0 0.3 GO:0045028 G-protein coupled nucleotide receptor activity(GO:0001608) G-protein coupled purinergic nucleotide receptor activity(GO:0045028)
0.0 0.3 GO:0005225 volume-sensitive anion channel activity(GO:0005225)
0.0 0.3 GO:0017166 vinculin binding(GO:0017166)
0.0 0.1 GO:0008241 peptidyl-dipeptidase activity(GO:0008241)
0.0 0.1 GO:0030977 taurine binding(GO:0030977)
0.0 0.2 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.4 GO:0005184 neuropeptide hormone activity(GO:0005184)
0.0 0.1 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.0 0.2 GO:0005523 tropomyosin binding(GO:0005523)
0.0 0.3 GO:0005537 mannose binding(GO:0005537)
0.0 0.3 GO:0008519 ammonium transmembrane transporter activity(GO:0008519)
0.0 0.3 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.2 GO:0005549 odorant binding(GO:0005549)
0.0 0.2 GO:0005041 low-density lipoprotein receptor activity(GO:0005041)
0.0 0.1 GO:1990254 keratin filament binding(GO:1990254)
0.0 0.0 GO:0035717 chemokine (C-C motif) ligand 7 binding(GO:0035717)
0.0 0.1 GO:0043426 MRF binding(GO:0043426)
0.0 0.1 GO:0003997 acyl-CoA oxidase activity(GO:0003997)
0.0 0.1 GO:0005250 A-type (transient outward) potassium channel activity(GO:0005250)
0.0 0.1 GO:0001594 trace-amine receptor activity(GO:0001594)
0.0 0.2 GO:0035925 mRNA 3'-UTR AU-rich region binding(GO:0035925)
0.0 0.2 GO:0051787 misfolded protein binding(GO:0051787)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 PID HDAC CLASSII PATHWAY Signaling events mediated by HDAC Class II
0.0 0.9 NABA PROTEOGLYCANS Genes encoding proteoglycans
0.0 0.6 PID S1P S1P1 PATHWAY S1P1 pathway
0.0 1.3 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.0 0.5 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.5 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.2 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.2 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.8 PID RETINOIC ACID PATHWAY Retinoic acid receptors-mediated signaling
0.0 0.4 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway
0.0 0.7 PID SYNDECAN 1 PATHWAY Syndecan-1-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.4 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.3 REACTOME TANDEM PORE DOMAIN POTASSIUM CHANNELS Genes involved in Tandem pore domain potassium channels
0.0 0.3 REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE Genes involved in Translocation of ZAP-70 to Immunological synapse
0.0 0.2 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.3 REACTOME P2Y RECEPTORS Genes involved in P2Y receptors
0.0 0.8 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 0.3 REACTOME CS DS DEGRADATION Genes involved in CS/DS degradation
0.0 0.6 REACTOME DEGRADATION OF THE EXTRACELLULAR MATRIX Genes involved in Degradation of the extracellular matrix
0.0 0.7 REACTOME CTLA4 INHIBITORY SIGNALING Genes involved in CTLA4 inhibitory signaling
0.0 0.9 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 0.4 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.3 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.3 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.3 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin
0.0 0.2 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.5 REACTOME ADP SIGNALLING THROUGH P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.0 0.1 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.4 REACTOME NOD1 2 SIGNALING PATHWAY Genes involved in NOD1/2 Signaling Pathway