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2D miR_HR1_12

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Results for Spdef

Z-value: 1.34

Motif logo

Transcription factors associated with Spdef

Gene Symbol Gene ID Gene Info
ENSMUSG00000024215.7 SAM pointed domain containing ets transcription factor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Spdefmm10_v2_chr17_-_27728889_277289560.313.3e-01Click!

Activity profile of Spdef motif

Sorted Z-values of Spdef motif

Promoter Log-likelihood Transcript Gene Gene Info
chr16_+_5007283 2.73 ENSMUST00000184439.1
small integral membrane protein 22
chr11_+_69965396 2.41 ENSMUST00000018713.6
claudin 7
chr5_+_113735782 2.27 ENSMUST00000065698.5
FIC domain containing
chr9_+_110476985 1.97 ENSMUST00000084948.4
ENSMUST00000061155.6
ENSMUST00000140686.1
ENSMUST00000084952.5
kinesin family member 9
chr12_-_84698769 1.89 ENSMUST00000095550.2
synapse differentiation inducing 1 like
chr10_+_34483400 1.81 ENSMUST00000019913.7
ENSMUST00000170771.1
fyn-related kinase
chr7_-_4546567 1.70 ENSMUST00000065957.5
synaptotagmin V
chr8_+_105305572 1.62 ENSMUST00000109375.2
engulfment and cell motility 3
chr7_+_141079759 1.56 ENSMUST00000066873.4
ENSMUST00000163041.1
plakophilin 3
chr4_+_118527229 1.49 ENSMUST00000030261.5
RIKEN cDNA 2610528J11 gene
chr5_+_117133567 1.48 ENSMUST00000179276.1
ENSMUST00000092889.5
ENSMUST00000145640.1
TAO kinase 3
chr9_+_107296843 1.46 ENSMUST00000167072.1
cytokine inducible SH2-containing protein
chr11_+_70647258 1.42 ENSMUST00000037534.7
ring finger protein 167
chr15_+_102102926 1.42 ENSMUST00000169627.1
ENSMUST00000046144.9
tensin like C1 domain-containing phosphatase
chr11_-_109722214 1.41 ENSMUST00000020938.7
family with sequence similarity 20, member A
chr3_-_5576233 1.40 ENSMUST00000059021.4
peroxisomal biogenesis factor 2
chr3_-_5576111 1.36 ENSMUST00000165309.1
ENSMUST00000164828.1
ENSMUST00000071280.5
peroxisomal biogenesis factor 2
chr5_+_66968416 1.33 ENSMUST00000038188.7
LIM and calponin homology domains 1
chr16_-_44016387 1.30 ENSMUST00000036174.3
GRAM domain containing 1C
chr16_+_5007306 1.30 ENSMUST00000178155.2
ENSMUST00000184256.1
ENSMUST00000185147.1
small integral membrane protein 22
chr15_-_54278420 1.29 ENSMUST00000079772.3
tumor necrosis factor receptor superfamily, member 11b (osteoprotegerin)
chr9_-_65908676 1.29 ENSMUST00000119245.1
ENSMUST00000134338.1
ENSMUST00000179395.1
thyroid hormone receptor interactor 4
chr19_-_5106967 1.28 ENSMUST00000025804.5
RAB1B, member RAS oncogene family
chr17_-_35979679 1.27 ENSMUST00000173724.1
ENSMUST00000172900.1
ENSMUST00000174849.1
proline-rich polypeptide 3
chr5_-_29735928 1.25 ENSMUST00000065372.3
predicted gene 5129
chr19_+_8920358 1.19 ENSMUST00000096243.5
beta-1,3-glucuronyltransferase 3 (glucuronosyltransferase I)
chr5_-_123865491 1.16 ENSMUST00000057145.5
niacin receptor 1
chr2_+_129592914 1.14 ENSMUST00000103203.1
signal-regulatory protein alpha
chr10_-_40025253 1.14 ENSMUST00000163705.2
expressed sequence AI317395
chr7_+_127841817 1.10 ENSMUST00000121705.1
syntaxin 4A (placental)
chr4_-_130279205 1.08 ENSMUST00000120126.2
serine incorporator 2
chr3_-_90243073 1.08 ENSMUST00000107369.1
cAMP responsive element binding protein 3-like 4
chr2_+_129592818 1.06 ENSMUST00000153491.1
ENSMUST00000161620.1
ENSMUST00000179001.1
signal-regulatory protein alpha
chr11_-_94474088 1.06 ENSMUST00000107786.1
ENSMUST00000107791.1
ENSMUST00000103166.2
ENSMUST00000107792.1
ENSMUST00000100561.3
ENSMUST00000107793.1
ENSMUST00000107788.1
ENSMUST00000107790.1
ENSMUST00000107789.1
ENSMUST00000107785.1
ENSMUST00000021234.8
calcium channel, voltage-dependent, T type, alpha 1G subunit
chr11_-_119355484 1.04 ENSMUST00000100172.2
ENSMUST00000005173.4
N-sulfoglucosamine sulfohydrolase (sulfamidase)
chr14_+_20674311 1.02 ENSMUST00000048657.8
Sec24 related gene family, member C (S. cerevisiae)
chr11_-_58330319 1.02 ENSMUST00000065533.2
predicted gene 9900
chr1_-_121328024 1.01 ENSMUST00000003818.7
insulin induced gene 2
chr7_+_127841752 0.99 ENSMUST00000033075.7
syntaxin 4A (placental)
chr11_-_48817332 0.99 ENSMUST00000047145.7
tripartite motif-containing 41
chr8_+_72161101 0.98 ENSMUST00000003121.8
RAB8A, member RAS oncogene family
chr7_+_45705088 0.94 ENSMUST00000080885.3
D site albumin promoter binding protein
chr10_+_39899304 0.94 ENSMUST00000181590.1
RIKEN cDNA 4930547M16 gene
chr6_-_128581597 0.94 ENSMUST00000060574.7
cDNA sequence BC048546
chr9_+_114978507 0.92 ENSMUST00000183104.1
oxysterol binding protein-like 10
chr7_-_126583177 0.92 ENSMUST00000098036.2
ENSMUST00000032962.4
ceroid lipofuscinosis, neuronal 3, juvenile (Batten, Spielmeyer-Vogt disease)
chr7_+_143473736 0.92 ENSMUST00000052348.5
solute carrier family 22 (organic cation transporter), member 18
chrX_+_163908982 0.91 ENSMUST00000069041.8
adaptor-related protein complex 1, sigma 2 subunit
chr17_+_28207778 0.90 ENSMUST00000002327.5
differentially expressed in FDCP 6
chrX_-_75416533 0.89 ENSMUST00000033542.4
mature T cell proliferation 1
chr17_-_57247632 0.88 ENSMUST00000005975.6
G protein-coupled receptor 108
chr12_+_80644212 0.87 ENSMUST00000085245.5
solute carrier family 39 (zinc transporter), member 9
chr17_+_80290206 0.87 ENSMUST00000061703.9
MORN repeat containing 2
chr14_+_54936456 0.86 ENSMUST00000037814.6
CKLF-like MARVEL transmembrane domain containing 5
chr19_-_6840590 0.85 ENSMUST00000170516.2
ENSMUST00000025903.5
ribosomal protein S6 kinase, polypeptide 4
chr8_+_113635787 0.85 ENSMUST00000035777.8
MON1 homolog b (yeast)
chr4_+_45972233 0.83 ENSMUST00000102929.1
tudor domain containing 7
chr2_-_52742142 0.83 ENSMUST00000138290.1
signal transducing adaptor molecule (SH3 domain and ITAM motif) 2
chr10_-_93311073 0.81 ENSMUST00000008542.5
ELK3, member of ETS oncogene family
chr11_-_70646972 0.80 ENSMUST00000014750.8
solute carrier family 25 (mitochondrial carrier oxoglutarate carrier), member 11
chr4_+_118526986 0.80 ENSMUST00000106367.1
RIKEN cDNA 2610528J11 gene
chr8_+_113635550 0.79 ENSMUST00000179926.1
MON1 homolog b (yeast)
chr9_-_88438898 0.78 ENSMUST00000173011.1
ENSMUST00000174806.1
sorting nexin 14
chr3_+_96576984 0.78 ENSMUST00000148290.1
predicted gene 16253
chr17_-_35979237 0.76 ENSMUST00000165613.2
ENSMUST00000173872.1
proline-rich polypeptide 3
chr13_+_40886758 0.75 ENSMUST00000069958.7
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme
chr9_-_88438940 0.75 ENSMUST00000165315.1
ENSMUST00000173039.1
sorting nexin 14
chr17_+_48232755 0.74 ENSMUST00000113251.3
ENSMUST00000048782.6
triggering receptor expressed on myeloid cells 1
chrX_-_75416562 0.73 ENSMUST00000033543.7
ENSMUST00000149863.2
ENSMUST00000114081.1
mature T cell proliferation 1
mature T cell proliferation 1
chr1_-_183297008 0.73 ENSMUST00000057062.5
BRO1 domain and CAAX motif containing
chr11_-_105944412 0.73 ENSMUST00000019734.4
ENSMUST00000184269.1
ENSMUST00000150563.1
cytochrome b-561
chr13_-_9878998 0.71 ENSMUST00000063093.9
cholinergic receptor, muscarinic 3, cardiac
chr9_+_107296682 0.71 ENSMUST00000168260.1
cytokine inducible SH2-containing protein
chr7_-_27355944 0.70 ENSMUST00000003857.6
Sh3kbp1 binding protein 1
chr12_+_76533540 0.69 ENSMUST00000075249.4
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr8_+_105269788 0.69 ENSMUST00000036127.2
ENSMUST00000163734.2
heat shock transcription factor 4
chrX_+_107816477 0.68 ENSMUST00000143975.1
ENSMUST00000144695.1
ENSMUST00000167154.1
family with sequence similarity 46, member D
chr17_+_47140942 0.68 ENSMUST00000077951.7
transcriptional regulating factor 1
chr8_-_70353243 0.67 ENSMUST00000075666.6
UPF1 regulator of nonsense transcripts homolog (yeast)
chr4_+_43562672 0.67 ENSMUST00000167751.1
ENSMUST00000132631.1
cAMP responsive element binding protein 3
chr5_+_129941949 0.67 ENSMUST00000051758.7
ENSMUST00000073945.4
vitamin K epoxide reductase complex, subunit 1-like 1
chr14_-_54253907 0.66 ENSMUST00000128231.1
defender against cell death 1
chr3_-_63964659 0.66 ENSMUST00000161659.1
solute carrier family 33 (acetyl-CoA transporter), member 1
chr9_+_118040475 0.66 ENSMUST00000044454.5
5-azacytidine induced gene 2
chr12_-_84361802 0.65 ENSMUST00000021659.1
ENSMUST00000065536.2
family with sequence similarity 161, member B
chr5_-_30907692 0.64 ENSMUST00000132034.2
ENSMUST00000132253.2
oligosaccharyltransferase 4 homolog (S. cerevisiae)
chr15_-_88819279 0.64 ENSMUST00000043087.8
ENSMUST00000162183.1
asparagine-linked glycosylation 12 (alpha-1,6-mannosyltransferase)
chr18_-_3281036 0.64 ENSMUST00000049942.6
ENSMUST00000139537.1
ENSMUST00000124747.1
cAMP responsive element modulator
chr1_+_85894281 0.64 ENSMUST00000027425.9
integral membrane protein 2C
chr2_-_127541385 0.64 ENSMUST00000103214.2
prominin 2
chrX_-_57338598 0.63 ENSMUST00000033468.4
ENSMUST00000114736.1
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr10_+_127290774 0.63 ENSMUST00000026475.8
ENSMUST00000139091.1
DNA-damage inducible transcript 3
chr2_+_145785980 0.63 ENSMUST00000110005.1
ENSMUST00000094480.4
Ras and Rab interactor 2
chr10_+_95417352 0.63 ENSMUST00000181781.1
RIKEN cDNA 5730420D15 gene
chr12_+_109747903 0.63 ENSMUST00000183084.1
ENSMUST00000182300.1
miRNA containing gene
chr18_-_46597299 0.62 ENSMUST00000036030.7
transmembrane emp24 protein transport domain containing 7
chr4_+_21848039 0.62 ENSMUST00000098238.2
ENSMUST00000108229.1
serine/arginine-rich splicing factor 18
chr11_+_21572221 0.62 ENSMUST00000020568.3
ENSMUST00000131135.1
WD repeat containing planar cell polarity effector
chr17_-_32947372 0.62 ENSMUST00000139353.1
cytochrome P450, family 4, subfamily f, polypeptide 13
chr4_+_155812489 0.62 ENSMUST00000030944.4
cyclin L2
chr17_-_25240112 0.61 ENSMUST00000038973.6
ENSMUST00000115154.4
N-acetylglucosamine-1-phosphotransferase, gamma subunit
chr9_+_118040509 0.60 ENSMUST00000133580.1
5-azacytidine induced gene 2
chr17_-_35074485 0.60 ENSMUST00000007259.3
lymphocyte antigen 6 complex, locus G6D
chr11_+_117654798 0.60 ENSMUST00000106344.1
trinucleotide repeat containing 6C
chr1_-_13589717 0.60 ENSMUST00000027068.4
translocating chain-associating membrane protein 1
chr2_-_127541412 0.59 ENSMUST00000028855.7
prominin 2
chr5_+_66968559 0.59 ENSMUST00000127184.1
LIM and calponin homology domains 1
chr18_-_46597480 0.59 ENSMUST00000151189.1
transmembrane emp24 protein transport domain containing 7
chr4_-_62519885 0.59 ENSMUST00000107444.1
ENSMUST00000030090.3
aminolevulinate, delta-, dehydratase
chr1_+_84839833 0.59 ENSMUST00000097672.3
F-box protein 36
chr16_-_19983005 0.59 ENSMUST00000058839.8
kelch-like 6
chr2_-_52742169 0.59 ENSMUST00000102759.1
ENSMUST00000127316.1
signal transducing adaptor molecule (SH3 domain and ITAM motif) 2
chr1_+_151755339 0.59 ENSMUST00000059498.5
ER degradation enhancer, mannosidase alpha-like 3
chr19_+_57361009 0.58 ENSMUST00000036407.4
family with sequence similarity 160, member B1
chr8_+_105269837 0.58 ENSMUST00000172525.1
ENSMUST00000174837.1
ENSMUST00000173859.1
heat shock transcription factor 4
chr11_+_117654211 0.57 ENSMUST00000026658.6
trinucleotide repeat containing 6C
chr7_+_28440927 0.56 ENSMUST00000078845.6
glia maturation factor, gamma
chr8_+_85840971 0.56 ENSMUST00000053771.7
ENSMUST00000161850.1
phosphorylase kinase beta
chr2_-_26445175 0.56 ENSMUST00000114082.2
ENSMUST00000091252.4
SEC16 homolog A (S. cerevisiae)
chrX_+_143518576 0.56 ENSMUST00000033640.7
p21 protein (Cdc42/Rac)-activated kinase 3
chr3_-_89393294 0.56 ENSMUST00000142119.1
ENSMUST00000029677.8
ENSMUST00000148361.1
zinc finger and BTB domain containing 7B
chr4_+_101647763 0.55 ENSMUST00000106927.1
leptin receptor overlapping transcript
chr11_-_48816936 0.55 ENSMUST00000140800.1
tripartite motif-containing 41
chr12_-_78861636 0.55 ENSMUST00000021536.7
ATPase, H+ transporting, lysosomal V1 subunit D
chr7_-_25718976 0.55 ENSMUST00000002683.2
coiled-coil domain containing 97
chr5_-_38561658 0.54 ENSMUST00000005234.9
WD repeat domain 1
chr17_-_24527925 0.54 ENSMUST00000176652.1
TNF receptor-associated factor 7
chr19_+_6363671 0.54 ENSMUST00000131252.1
splicing factor 1
chr4_+_101647712 0.53 ENSMUST00000030254.8
leptin receptor overlapping transcript
chr6_+_30509849 0.53 ENSMUST00000031797.4
serine-rich single-pass membrane protein 1
chr4_+_3678108 0.52 ENSMUST00000041377.6
ENSMUST00000103010.3
Yamaguchi sarcoma viral (v-yes-1) oncogene homolog
chrX_+_101254528 0.52 ENSMUST00000062000.4
forkhead box O4
chr9_+_30427329 0.52 ENSMUST00000164099.1
sorting nexin 19
chr13_+_22043189 0.52 ENSMUST00000110452.1
histone cluster 1, H2bj
chr2_+_6322621 0.51 ENSMUST00000114937.1
USP6 N-terminal like
chr8_-_65129317 0.51 ENSMUST00000098713.3
cDNA sequence BC030870
chr11_+_109362771 0.51 ENSMUST00000020930.7
ENSMUST00000106702.3
guanine nucleotide binding protein, alpha 13
chr14_+_54254124 0.51 ENSMUST00000180359.1
abhydrolase domain containing 4
chr9_+_88438598 0.50 ENSMUST00000181138.1
RIKEN cDNA 4932427H20 gene
chr5_+_66968961 0.50 ENSMUST00000132991.1
LIM and calponin homology domains 1
chr6_-_72390659 0.50 ENSMUST00000059983.9
vesicle-associated membrane protein 8
chr9_+_6168601 0.50 ENSMUST00000168039.1
platelet-derived growth factor, D polypeptide
chr9_+_56994932 0.50 ENSMUST00000034832.6
protein tyrosine phosphatase, non-receptor type 9
chr7_+_28441026 0.50 ENSMUST00000135686.1
glia maturation factor, gamma
chr7_-_100547620 0.49 ENSMUST00000064334.2
RIKEN cDNA D630004N19 gene
chr7_+_28071230 0.49 ENSMUST00000138392.1
ENSMUST00000076648.7
Fc fragment of IgG binding protein
chr11_-_72795801 0.49 ENSMUST00000079681.5
cytochrome b5 domain containing 2
chr8_-_85840877 0.49 ENSMUST00000034140.7
integrin alpha FG-GAP repeat containing 1
chr17_+_32506446 0.49 ENSMUST00000165999.1
cytochrome P450, family 4, subfamily f, polypeptide 17
chr4_-_129573637 0.49 ENSMUST00000102596.1
lymphocyte protein tyrosine kinase
chr2_+_166805506 0.49 ENSMUST00000099078.3
ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited)
chr4_-_119174178 0.49 ENSMUST00000106355.3
zinc finger protein 691
chr7_-_126583523 0.48 ENSMUST00000125508.1
ENSMUST00000147086.1
ENSMUST00000150587.1
ceroid lipofuscinosis, neuronal 3, juvenile (Batten, Spielmeyer-Vogt disease)
chr6_+_4003926 0.48 ENSMUST00000031670.8
guanine nucleotide binding protein (G protein), gamma 11
chr11_+_97050594 0.48 ENSMUST00000090020.5
oxysterol binding protein-like 7
chr15_+_76671615 0.47 ENSMUST00000037551.8
protein phosphatase 1, regulatory (inhibitor) subunit 16A
chr1_+_95313607 0.47 ENSMUST00000059975.6
family with sequence similarity 174, member A
chr5_+_57718021 0.46 ENSMUST00000094783.3
ENSMUST00000068110.7
protocadherin 7
chrX_-_107816238 0.46 ENSMUST00000120722.1
RIKEN cDNA 2610002M06 gene
chr7_+_131032061 0.46 ENSMUST00000084509.3
deleted in malignant brain tumors 1
chr17_-_24527830 0.46 ENSMUST00000176353.1
ENSMUST00000176237.1
TNF receptor-associated factor 7
chr7_-_73537621 0.45 ENSMUST00000172704.1
chromodomain helicase DNA binding protein 2
chr16_-_94370450 0.45 ENSMUST00000138514.1
phosphatidylinositol glycan anchor biosynthesis, class P
chr11_-_5542177 0.45 ENSMUST00000020776.4
coiled-coil domain containing 117
chr17_+_37050631 0.45 ENSMUST00000172792.1
ENSMUST00000174347.1
gamma-aminobutyric acid (GABA) B receptor, 1
chr5_+_115631902 0.45 ENSMUST00000031492.8
RAB35, member RAS oncogene family
chr11_+_97050811 0.44 ENSMUST00000168565.1
oxysterol binding protein-like 7
chr6_-_120822680 0.44 ENSMUST00000019354.8
ATPase, H+ transporting, lysosomal V1 subunit E1
chr10_-_30655859 0.43 ENSMUST00000092610.4
nuclear receptor coactivator 7
chr18_-_10610124 0.43 ENSMUST00000097670.3
establishment of cohesion 1 homolog 1 (S. cerevisiae)
chr17_+_84956718 0.42 ENSMUST00000112305.3
protein phosphatase 1B, magnesium dependent, beta isoform
chr5_-_115272883 0.42 ENSMUST00000040555.8
ENSMUST00000112096.2
ENSMUST00000112097.1
ring finger protein 10
chr18_-_34373313 0.41 ENSMUST00000006027.5
receptor accessory protein 5
chr17_-_25919506 0.41 ENSMUST00000164982.1
ENSMUST00000179998.1
ENSMUST00000167626.1
ENSMUST00000164738.1
ENSMUST00000026826.7
ENSMUST00000167018.1
Rab40c, member RAS oncogene family
chr2_-_121171107 0.41 ENSMUST00000163766.1
ENSMUST00000146243.1
zinc finger SCAN domains 29
chr14_-_75754475 0.41 ENSMUST00000049168.7
component of oligomeric golgi complex 3
chr10_-_95324072 0.40 ENSMUST00000053594.5
CASP2 and RIPK1 domain containing adaptor with death domain
chr9_+_80165013 0.40 ENSMUST00000035889.8
ENSMUST00000113268.1
myosin VI
chrX_+_119927196 0.40 ENSMUST00000040961.2
ENSMUST00000113366.1
poly(A) binding protein, cytoplasmic 5
chr19_+_40894692 0.40 ENSMUST00000050092.6
zinc finger protein 518A
chr9_-_21918089 0.40 ENSMUST00000128442.1
ENSMUST00000119055.1
ENSMUST00000122211.1
ENSMUST00000115351.3
RAB3D, member RAS oncogene family
chr13_+_40859768 0.40 ENSMUST00000110191.2
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme
chr5_-_25100624 0.39 ENSMUST00000030784.7
protein kinase, AMP-activated, gamma 2 non-catalytic subunit
chr18_-_10610048 0.39 ENSMUST00000115864.1
establishment of cohesion 1 homolog 1 (S. cerevisiae)
chr11_+_83302641 0.39 ENSMUST00000176430.1
ENSMUST00000065692.7
adaptor-related protein complex 2, beta 1 subunit
chr9_-_110476637 0.39 ENSMUST00000111934.1
ENSMUST00000068025.6
kelch-like 18
chr11_-_100850724 0.39 ENSMUST00000004143.2
signal transducer and activator of transcription 5B
chr14_-_78536762 0.39 ENSMUST00000123853.1
A kinase (PRKA) anchor protein 11
chr18_+_74268251 0.39 ENSMUST00000097530.3
methyl-CpG binding domain protein 1
chr7_-_13034722 0.38 ENSMUST00000005711.4
charged multivesicular body protein 2A
chr14_-_78536854 0.38 ENSMUST00000022593.5
A kinase (PRKA) anchor protein 11
chr11_+_83302817 0.38 ENSMUST00000142680.1
adaptor-related protein complex 2, beta 1 subunit
chr19_+_6363719 0.38 ENSMUST00000113489.1
ENSMUST00000113488.1
splicing factor 1
chr19_+_46599081 0.38 ENSMUST00000138302.2
ENSMUST00000099376.4
WW domain binding protein 1 like
chr3_+_135825648 0.37 ENSMUST00000180196.1
solute carrier family 39 (metal ion transporter), member 8
chr1_+_58802492 0.37 ENSMUST00000165549.1
caspase 8
chr9_+_57910974 0.37 ENSMUST00000163329.1
ubiquitin-like 7 (bone marrow stromal cell-derived)
chr11_+_120361506 0.37 ENSMUST00000026445.2
fascin homolog 2, actin-bundling protein, retinal (Strongylocentrotus purpuratus)
chr8_-_83332416 0.37 ENSMUST00000177594.1
ENSMUST00000053902.3
ELMO/CED-12 domain containing 2
chr13_-_22042949 0.36 ENSMUST00000091741.4
histone cluster 1, H2ag

Network of associatons between targets according to the STRING database.

First level regulatory network of Spdef

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.1 GO:1902568 positive regulation of eosinophil degranulation(GO:0043311) positive regulation of eosinophil activation(GO:1902568)
0.5 1.6 GO:0019085 early viral transcription(GO:0019085)
0.4 1.1 GO:0071846 actin filament debranching(GO:0071846)
0.3 1.4 GO:0044565 dendritic cell proliferation(GO:0044565)
0.3 1.0 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.3 1.2 GO:2001287 negative regulation of caveolin-mediated endocytosis(GO:2001287)
0.3 0.9 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.3 1.4 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
0.3 1.1 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.3 1.6 GO:0002159 desmosome assembly(GO:0002159)
0.2 1.2 GO:0050651 dermatan sulfate proteoglycan biosynthetic process(GO:0050651)
0.2 0.7 GO:0019043 positive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response(GO:0006990) establishment of viral latency(GO:0019043) release from viral latency(GO:0019046)
0.2 0.7 GO:0017187 peptidyl-glutamic acid carboxylation(GO:0017187) protein carboxylation(GO:0018214)
0.2 0.9 GO:0043376 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376)
0.2 1.1 GO:0060398 regulation of growth hormone receptor signaling pathway(GO:0060398)
0.2 0.6 GO:2000016 negative regulation of determination of dorsal identity(GO:2000016)
0.2 0.6 GO:0016256 N-glycan processing to lysosome(GO:0016256)
0.2 1.0 GO:0034421 post-translational protein acetylation(GO:0034421)
0.2 0.8 GO:2000439 positive regulation of monocyte extravasation(GO:2000439)
0.2 1.1 GO:0036438 maintenance of lens transparency(GO:0036438)
0.2 0.5 GO:0060369 positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369) positive regulation of dendritic cell apoptotic process(GO:2000670)
0.2 0.5 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.2 0.5 GO:0070625 zymogen granule exocytosis(GO:0070625)
0.2 3.3 GO:0016558 protein import into peroxisome matrix(GO:0016558)
0.2 2.8 GO:0032463 negative regulation of protein homooligomerization(GO:0032463)
0.2 1.1 GO:1904217 regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904217) positive regulation of CDP-diacylglycerol-serine O-phosphatidyltransferase activity(GO:1904219) positive regulation of serine C-palmitoyltransferase activity(GO:1904222)
0.1 0.7 GO:0070945 neutrophil mediated killing of gram-negative bacterium(GO:0070945)
0.1 0.7 GO:0007207 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.1 0.5 GO:0030043 actin filament fragmentation(GO:0030043)
0.1 0.7 GO:0032201 telomere maintenance via semi-conservative replication(GO:0032201)
0.1 1.3 GO:0042483 negative regulation of odontogenesis(GO:0042483)
0.1 1.4 GO:0070166 enamel mineralization(GO:0070166)
0.1 0.4 GO:1903722 regulation of centriole elongation(GO:1903722)
0.1 0.6 GO:0044314 protein K27-linked ubiquitination(GO:0044314)
0.1 0.6 GO:0090521 glomerular visceral epithelial cell migration(GO:0090521)
0.1 0.6 GO:0035977 protein deglycosylation involved in glycoprotein catabolic process(GO:0035977) protein demannosylation(GO:0036507) protein alpha-1,2-demannosylation(GO:0036508) glycoprotein ERAD pathway(GO:0097466) mannose trimming involved in glycoprotein ERAD pathway(GO:1904382)
0.1 0.3 GO:0044837 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837) ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611)
0.1 0.2 GO:1903774 positive regulation of viral budding via host ESCRT complex(GO:1903774)
0.1 0.9 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.1 0.9 GO:0071397 cellular response to cholesterol(GO:0071397)
0.1 0.3 GO:1900060 negative regulation of ceramide biosynthetic process(GO:1900060)
0.1 2.0 GO:0007095 mitotic G2 DNA damage checkpoint(GO:0007095)
0.1 0.6 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.1 1.3 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.1 0.4 GO:0006481 C-terminal protein methylation(GO:0006481)
0.1 0.3 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.1 0.3 GO:0032058 positive regulation of translational initiation in response to stress(GO:0032058)
0.1 0.4 GO:0010626 negative regulation of Schwann cell proliferation(GO:0010626)
0.1 0.4 GO:0018125 peptidyl-cysteine methylation(GO:0018125)
0.1 0.2 GO:2000845 positive regulation of testosterone secretion(GO:2000845)
0.1 1.2 GO:0035278 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.1 0.4 GO:0070672 response to interleukin-15(GO:0070672)
0.1 1.0 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.1 0.2 GO:1904457 positive regulation of neuronal action potential(GO:1904457)
0.1 0.4 GO:0048227 plasma membrane to endosome transport(GO:0048227)
0.1 0.7 GO:0070574 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.1 1.0 GO:0060363 cranial suture morphogenesis(GO:0060363)
0.1 2.4 GO:0006910 phagocytosis, recognition(GO:0006910)
0.1 0.6 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.1 2.0 GO:0071801 regulation of podosome assembly(GO:0071801)
0.1 0.4 GO:0014053 negative regulation of gamma-aminobutyric acid secretion(GO:0014053)
0.1 2.2 GO:0007205 protein kinase C-activating G-protein coupled receptor signaling pathway(GO:0007205)
0.1 0.1 GO:1901668 regulation of superoxide dismutase activity(GO:1901668)
0.1 0.2 GO:0038163 endomitotic cell cycle(GO:0007113) thrombopoietin-mediated signaling pathway(GO:0038163) positive regulation of male germ cell proliferation(GO:2000256)
0.1 0.2 GO:1904211 membrane protein proteolysis involved in retrograde protein transport, ER to cytosol(GO:1904211)
0.1 0.9 GO:0033327 Leydig cell differentiation(GO:0033327)
0.1 1.3 GO:0033169 histone H3-K9 demethylation(GO:0033169)
0.1 0.3 GO:0050916 sensory perception of sweet taste(GO:0050916) sensory perception of umami taste(GO:0050917)
0.1 1.0 GO:0098969 neurotransmitter receptor transport to plasma membrane(GO:0098877) neurotransmitter receptor transport to postsynaptic membrane(GO:0098969) establishment of protein localization to postsynaptic membrane(GO:1903540)
0.1 0.2 GO:0072720 response to sorbitol(GO:0072708) response to dithiothreitol(GO:0072720)
0.1 0.2 GO:2000847 negative regulation of corticosteroid hormone secretion(GO:2000847) negative regulation of glucocorticoid secretion(GO:2000850)
0.1 0.2 GO:1904732 regulation of electron carrier activity(GO:1904732) regulation of cytochrome-c oxidase activity(GO:1904959)
0.1 0.2 GO:2000170 positive regulation of peptidyl-cysteine S-nitrosylation(GO:2000170)
0.1 1.5 GO:0097352 autophagosome maturation(GO:0097352)
0.1 0.2 GO:1990166 protein localization to site of double-strand break(GO:1990166)
0.1 0.7 GO:0071257 cellular response to electrical stimulus(GO:0071257)
0.1 0.2 GO:0061428 negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428)
0.0 0.1 GO:0036015 response to interleukin-3(GO:0036015) cellular response to interleukin-3(GO:0036016)
0.0 0.6 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.5 GO:0070474 positive regulation of uterine smooth muscle contraction(GO:0070474)
0.0 0.2 GO:1903898 regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202) negative regulation of PERK-mediated unfolded protein response(GO:1903898)
0.0 0.2 GO:1905077 negative regulation of interleukin-17 secretion(GO:1905077)
0.0 0.5 GO:0031584 activation of phospholipase D activity(GO:0031584)
0.0 1.7 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 1.3 GO:1903020 positive regulation of glycoprotein metabolic process(GO:1903020)
0.0 0.2 GO:1900226 negative regulation of NLRP3 inflammasome complex assembly(GO:1900226)
0.0 0.3 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.0 0.4 GO:0036462 TRAIL-activated apoptotic signaling pathway(GO:0036462)
0.0 0.2 GO:0072738 response to diamide(GO:0072737) cellular response to diamide(GO:0072738)
0.0 0.2 GO:0032485 regulation of Ral protein signal transduction(GO:0032485)
0.0 0.3 GO:0097039 protein linear polyubiquitination(GO:0097039)
0.0 0.3 GO:1901727 positive regulation of histone deacetylase activity(GO:1901727)
0.0 0.4 GO:0070236 negative regulation of activation-induced cell death of T cells(GO:0070236)
0.0 0.3 GO:0032534 regulation of microvillus assembly(GO:0032534)
0.0 0.4 GO:2000169 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083) regulation of peptidyl-cysteine S-nitrosylation(GO:2000169)
0.0 1.0 GO:0045662 negative regulation of myoblast differentiation(GO:0045662)
0.0 0.1 GO:0044313 protein K6-linked deubiquitination(GO:0044313)
0.0 0.2 GO:0015760 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 0.2 GO:0006041 glucosamine metabolic process(GO:0006041)
0.0 0.8 GO:0010763 positive regulation of fibroblast migration(GO:0010763)
0.0 0.3 GO:0090315 negative regulation of protein targeting to membrane(GO:0090315)
0.0 0.1 GO:0046381 CMP-N-acetylneuraminate metabolic process(GO:0046381)
0.0 0.4 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977)
0.0 0.2 GO:0031145 anaphase-promoting complex-dependent catabolic process(GO:0031145)
0.0 1.2 GO:0045661 regulation of myoblast differentiation(GO:0045661)
0.0 2.3 GO:0038083 peptidyl-tyrosine autophosphorylation(GO:0038083)
0.0 0.8 GO:0002089 lens morphogenesis in camera-type eye(GO:0002089)
0.0 0.3 GO:1990403 embryonic brain development(GO:1990403)
0.0 0.6 GO:0095500 acetylcholine receptor signaling pathway(GO:0095500) signal transduction involved in cellular response to ammonium ion(GO:1903831) response to acetylcholine(GO:1905144) cellular response to acetylcholine(GO:1905145)
0.0 0.1 GO:0019276 UDP-N-acetylgalactosamine metabolic process(GO:0019276)
0.0 0.9 GO:0006829 zinc II ion transport(GO:0006829)
0.0 0.2 GO:0071955 recycling endosome to Golgi transport(GO:0071955)
0.0 0.5 GO:0060218 hematopoietic stem cell differentiation(GO:0060218)
0.0 0.6 GO:0006691 leukotriene metabolic process(GO:0006691)
0.0 0.6 GO:0046686 response to cadmium ion(GO:0046686)
0.0 0.4 GO:0032688 negative regulation of interferon-beta production(GO:0032688)
0.0 0.2 GO:0032532 regulation of microvillus length(GO:0032532)
0.0 2.3 GO:0006888 ER to Golgi vesicle-mediated transport(GO:0006888)
0.0 0.5 GO:0001833 inner cell mass cell proliferation(GO:0001833)
0.0 0.1 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.0 0.8 GO:0010738 regulation of protein kinase A signaling(GO:0010738)
0.0 0.9 GO:0015893 drug transport(GO:0015893)
0.0 0.1 GO:0051715 cytolysis in other organism(GO:0051715)
0.0 0.6 GO:0050853 B cell receptor signaling pathway(GO:0050853)
0.0 0.4 GO:0030220 platelet formation(GO:0030220)
0.0 0.2 GO:0002756 MyD88-independent toll-like receptor signaling pathway(GO:0002756)
0.0 0.1 GO:0061146 Peyer's patch morphogenesis(GO:0061146)
0.0 0.1 GO:0061739 protein lipidation involved in autophagosome assembly(GO:0061739)
0.0 0.4 GO:0048712 negative regulation of astrocyte differentiation(GO:0048712)
0.0 0.1 GO:0006108 malate metabolic process(GO:0006108)
0.0 0.2 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.3 GO:0006044 N-acetylglucosamine metabolic process(GO:0006044)
0.0 0.1 GO:0031848 protection from non-homologous end joining at telomere(GO:0031848)
0.0 0.5 GO:0045742 positive regulation of epidermal growth factor receptor signaling pathway(GO:0045742)
0.0 1.0 GO:0030968 endoplasmic reticulum unfolded protein response(GO:0030968)
0.0 0.2 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.0 0.3 GO:0035721 intraciliary retrograde transport(GO:0035721)
0.0 0.1 GO:0002426 immunoglobulin production in mucosal tissue(GO:0002426)
0.0 0.9 GO:0060612 adipose tissue development(GO:0060612)
0.0 0.2 GO:0031937 positive regulation of chromatin silencing(GO:0031937)
0.0 0.3 GO:0002446 neutrophil mediated immunity(GO:0002446)
0.0 0.3 GO:0045648 positive regulation of erythrocyte differentiation(GO:0045648)
0.0 0.2 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.0 0.5 GO:0061512 protein localization to cilium(GO:0061512)
0.0 0.2 GO:0030502 negative regulation of bone mineralization(GO:0030502)
0.0 0.6 GO:0007029 endoplasmic reticulum organization(GO:0007029)
0.0 0.0 GO:1902277 negative regulation of pancreatic amylase secretion(GO:1902277)
0.0 0.2 GO:1902857 positive regulation of nonmotile primary cilium assembly(GO:1902857)
0.0 0.2 GO:0002227 innate immune response in mucosa(GO:0002227)
0.0 0.2 GO:0007220 Notch receptor processing(GO:0007220)
0.0 0.2 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.2 GO:0009048 dosage compensation by inactivation of X chromosome(GO:0009048)
0.0 0.5 GO:0042462 eye photoreceptor cell development(GO:0042462)
0.0 0.6 GO:0006687 glycosphingolipid metabolic process(GO:0006687)
0.0 0.5 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 0.2 GO:0016045 detection of bacterium(GO:0016045) detection of other organism(GO:0098543)
0.0 0.1 GO:0002829 negative regulation of type 2 immune response(GO:0002829)
0.0 0.1 GO:0009249 protein lipoylation(GO:0009249)
0.0 0.4 GO:0010800 positive regulation of peptidyl-threonine phosphorylation(GO:0010800)
0.0 0.2 GO:0045948 positive regulation of translational initiation(GO:0045948)
0.0 0.0 GO:1903588 negative regulation of blood vessel endothelial cell proliferation involved in sprouting angiogenesis(GO:1903588)
0.0 0.3 GO:0043551 regulation of phosphatidylinositol 3-kinase activity(GO:0043551)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.6 GO:0005914 spot adherens junction(GO:0005914)
0.3 1.7 GO:1990769 proximal neuron projection(GO:1990769)
0.3 1.2 GO:0044393 microspike(GO:0044393)
0.3 2.1 GO:0000322 storage vacuole(GO:0000322)
0.3 2.8 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.2 0.6 GO:0036488 CHOP-C/EBP complex(GO:0036488)
0.2 0.5 GO:0034666 integrin alpha2-beta1 complex(GO:0034666)
0.2 0.5 GO:0032280 symmetric synapse(GO:0032280)
0.1 0.5 GO:1990415 Pex17p-Pex14p docking complex(GO:1990415) peroxisomal importomer complex(GO:1990429)
0.1 1.0 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.1 0.4 GO:0030690 Noc1p-Noc2p complex(GO:0030690)
0.1 0.7 GO:0044530 supraspliceosomal complex(GO:0044530)
0.1 2.4 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.1 0.4 GO:0038039 G-protein coupled receptor heterodimeric complex(GO:0038039)
0.1 0.4 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.1 0.3 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.1 1.3 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.1 1.3 GO:0030127 COPII vesicle coat(GO:0030127)
0.1 0.6 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.1 0.5 GO:0030670 phagocytic vesicle membrane(GO:0030670)
0.1 0.3 GO:0035339 SPOTS complex(GO:0035339)
0.1 0.3 GO:0071797 LUBAC complex(GO:0071797)
0.1 0.2 GO:0044316 cone cell pedicle(GO:0044316)
0.1 0.9 GO:0030008 TRAPP complex(GO:0030008)
0.1 0.8 GO:0033391 chromatoid body(GO:0033391)
0.0 0.6 GO:0005766 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0 0.4 GO:0098554 cytoplasmic side of endoplasmic reticulum membrane(GO:0098554)
0.0 0.3 GO:0019815 B cell receptor complex(GO:0019815)
0.0 2.0 GO:0002102 podosome(GO:0002102)
0.0 1.2 GO:0045334 clathrin-coated endocytic vesicle(GO:0045334)
0.0 0.3 GO:0097441 basilar dendrite(GO:0097441)
0.0 0.4 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.5 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.0 0.7 GO:0098984 asymmetric synapse(GO:0032279) neuron to neuron synapse(GO:0098984)
0.0 0.2 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.0 0.2 GO:0070765 gamma-secretase complex(GO:0070765)
0.0 2.5 GO:0005776 autophagosome(GO:0005776)
0.0 1.3 GO:0055038 recycling endosome membrane(GO:0055038)
0.0 1.6 GO:0005801 cis-Golgi network(GO:0005801)
0.0 0.7 GO:0070971 endoplasmic reticulum exit site(GO:0070971)
0.0 0.3 GO:0030991 intraciliary transport particle A(GO:0030991)
0.0 0.4 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.6 GO:0042588 zymogen granule(GO:0042588)
0.0 0.3 GO:0030663 COPI vesicle coat(GO:0030126) COPI-coated vesicle membrane(GO:0030663)
0.0 1.8 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 1.2 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 0.3 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.2 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.1 GO:1990130 Iml1 complex(GO:1990130)
0.0 0.2 GO:0089701 U2AF(GO:0089701)
0.0 0.2 GO:0072557 IPAF inflammasome complex(GO:0072557)
0.0 0.3 GO:0031209 SCAR complex(GO:0031209)
0.0 1.0 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.6 GO:0044447 axoneme part(GO:0044447)
0.0 3.3 GO:0031234 extrinsic component of cytoplasmic side of plasma membrane(GO:0031234)
0.0 0.4 GO:0031588 nucleotide-activated protein kinase complex(GO:0031588)
0.0 0.4 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 0.2 GO:0031105 septin complex(GO:0031105)
0.0 0.2 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.1 GO:0070419 nonhomologous end joining complex(GO:0070419)
0.0 0.0 GO:0017133 mitochondrial electron transfer flavoprotein complex(GO:0017133) electron transfer flavoprotein complex(GO:0045251)
0.0 0.4 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.2 GO:0032433 filopodium tip(GO:0032433)
0.0 0.1 GO:0033178 proton-transporting two-sector ATPase complex, catalytic domain(GO:0033178)
0.0 1.2 GO:0030864 cortical actin cytoskeleton(GO:0030864)
0.0 0.3 GO:0030904 retromer complex(GO:0030904)
0.0 0.3 GO:0005839 proteasome core complex(GO:0005839)
0.0 0.6 GO:0000307 cyclin-dependent protein kinase holoenzyme complex(GO:0000307)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 2.1 GO:0016230 sphingomyelin phosphodiesterase activator activity(GO:0016230)
0.3 1.1 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.3 0.8 GO:0015140 malate transmembrane transporter activity(GO:0015140)
0.3 1.1 GO:0008332 low voltage-gated calcium channel activity(GO:0008332)
0.2 0.7 GO:0022865 transmembrane electron transfer carrier(GO:0022865)
0.2 1.2 GO:0072542 protein phosphatase activator activity(GO:0072542)
0.2 0.9 GO:0045131 pre-mRNA branch point binding(GO:0045131)
0.2 0.7 GO:0031726 CCR1 chemokine receptor binding(GO:0031726)
0.2 0.8 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.2 0.5 GO:0005128 erythropoietin receptor binding(GO:0005128)
0.2 0.6 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.1 0.1 GO:0030348 syntaxin-3 binding(GO:0030348)
0.1 0.9 GO:0051185 coenzyme transporter activity(GO:0051185)
0.1 0.7 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.1 0.3 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.1 0.3 GO:0031752 D5 dopamine receptor binding(GO:0031752)
0.1 0.5 GO:0042610 CD8 receptor binding(GO:0042610)
0.1 1.6 GO:0045294 alpha-catenin binding(GO:0045294)
0.1 0.4 GO:0035877 death effector domain binding(GO:0035877)
0.1 0.4 GO:0003880 protein C-terminal carboxyl O-methyltransferase activity(GO:0003880)
0.1 0.4 GO:0089720 caspase binding(GO:0089720)
0.1 1.2 GO:0015194 L-serine transmembrane transporter activity(GO:0015194) serine transmembrane transporter activity(GO:0022889)
0.1 1.1 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.1 0.6 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.1 0.6 GO:0030550 acetylcholine receptor inhibitor activity(GO:0030550)
0.1 0.4 GO:0004965 G-protein coupled GABA receptor activity(GO:0004965)
0.1 0.2 GO:0004346 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.1 0.6 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.1 1.0 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.1 0.3 GO:0000822 inositol hexakisphosphate binding(GO:0000822) inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.1 1.1 GO:0035497 cAMP response element binding(GO:0035497)
0.1 0.3 GO:0050265 RNA uridylyltransferase activity(GO:0050265)
0.1 0.6 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.1 1.9 GO:0070566 adenylyltransferase activity(GO:0070566)
0.1 0.4 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.1 0.3 GO:0004699 calcium-independent protein kinase C activity(GO:0004699)
0.1 0.3 GO:0004342 glucosamine-6-phosphate deaminase activity(GO:0004342)
0.1 1.5 GO:0034237 protein kinase A regulatory subunit binding(GO:0034237)
0.1 0.4 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.1 1.5 GO:0004709 MAP kinase kinase kinase activity(GO:0004709)
0.1 0.2 GO:0031711 bradykinin receptor binding(GO:0031711)
0.1 1.4 GO:0031489 myosin V binding(GO:0031489)
0.1 2.8 GO:0001786 phosphatidylserine binding(GO:0001786)
0.1 1.5 GO:0080025 phosphatidylinositol-3,5-bisphosphate binding(GO:0080025)
0.0 0.1 GO:0030060 L-malate dehydrogenase activity(GO:0030060)
0.0 0.7 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.2 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427) calcium-dependent protein kinase regulator activity(GO:0010858)
0.0 0.1 GO:0001888 glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0001888)
0.0 0.2 GO:0043812 phosphatidylinositol-4-phosphate phosphatase activity(GO:0043812)
0.0 0.4 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.8 GO:0005161 platelet-derived growth factor receptor binding(GO:0005161)
0.0 1.4 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.2 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.0 0.5 GO:0004579 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.0 0.3 GO:0070290 N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.4 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.4 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.7 GO:0048038 quinone binding(GO:0048038)
0.0 0.8 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 1.3 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 2.3 GO:0004715 non-membrane spanning protein tyrosine kinase activity(GO:0004715)
0.0 0.2 GO:0047134 protein-disulfide reductase activity(GO:0047134)
0.0 2.2 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.6 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.1 GO:0016501 prostacyclin receptor activity(GO:0016501)
0.0 0.9 GO:0015238 drug transmembrane transporter activity(GO:0015238)
0.0 2.0 GO:0045309 protein phosphorylated amino acid binding(GO:0045309)
0.0 0.2 GO:0031821 G-protein coupled serotonin receptor binding(GO:0031821)
0.0 1.3 GO:0016922 ligand-dependent nuclear receptor binding(GO:0016922)
0.0 0.4 GO:0070513 death domain binding(GO:0070513)
0.0 0.4 GO:0031210 phosphatidylcholine binding(GO:0031210)
0.0 0.1 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.0 0.4 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.0 1.3 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.2 GO:0046790 virion binding(GO:0046790)
0.0 0.2 GO:1990380 Lys63-specific deubiquitinase activity(GO:0061578) Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.7 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.2 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.2 GO:0050693 LBD domain binding(GO:0050693)
0.0 0.2 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.0 0.2 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.2 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.3 GO:0030296 protein tyrosine kinase activator activity(GO:0030296)
0.0 0.2 GO:0016531 copper chaperone activity(GO:0016531)
0.0 0.2 GO:0036312 phosphatidylinositol 3-kinase regulatory subunit binding(GO:0036312)
0.0 1.2 GO:0030276 clathrin binding(GO:0030276)
0.0 2.2 GO:0004860 protein kinase inhibitor activity(GO:0004860)
0.0 0.2 GO:0003909 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0 0.5 GO:0032266 phosphatidylinositol-3-phosphate binding(GO:0032266)
0.0 0.3 GO:0046030 inositol-polyphosphate 5-phosphatase activity(GO:0004445) inositol trisphosphate phosphatase activity(GO:0046030)
0.0 0.1 GO:0030368 interleukin-17 receptor activity(GO:0030368)
0.0 0.6 GO:0050681 androgen receptor binding(GO:0050681)
0.0 0.1 GO:0035312 5'-3' exodeoxyribonuclease activity(GO:0035312)
0.0 0.3 GO:0070577 lysine-acetylated histone binding(GO:0070577)
0.0 1.3 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.4 GO:0035259 glucocorticoid receptor binding(GO:0035259)
0.0 0.2 GO:0030628 pre-mRNA 3'-splice site binding(GO:0030628)
0.0 0.3 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.3 GO:0035004 phosphatidylinositol 3-kinase activity(GO:0035004)
0.0 0.1 GO:0038062 protein tyrosine kinase collagen receptor activity(GO:0038062)
0.0 0.3 GO:0005149 interleukin-1 receptor binding(GO:0005149)
0.0 0.2 GO:0017166 vinculin binding(GO:0017166)
0.0 0.3 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.6 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.7 GO:0061733 peptide-lysine-N-acetyltransferase activity(GO:0061733)
0.0 1.4 GO:0005089 Rho guanyl-nucleotide exchange factor activity(GO:0005089)
0.0 0.4 GO:0030374 ligand-dependent nuclear receptor transcription coactivator activity(GO:0030374)
0.0 1.2 GO:0000149 SNARE binding(GO:0000149)
0.0 1.5 GO:0017124 SH3 domain binding(GO:0017124)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.3 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.1 1.1 PID IL5 PATHWAY IL5-mediated signaling events
0.0 1.3 PID P38 ALPHA BETA PATHWAY Regulation of p38-alpha and p38-beta
0.0 1.4 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.7 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 0.4 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.7 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 2.2 PID RAC1 REG PATHWAY Regulation of RAC1 activity
0.0 1.4 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.8 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.2 PID AR NONGENOMIC PATHWAY Nongenotropic Androgen signaling
0.0 0.5 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.9 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 0.6 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.6 PID HIV NEF PATHWAY HIV-1 Nef: Negative effector of Fas and TNF-alpha
0.0 0.1 PID IL27 PATHWAY IL27-mediated signaling events
0.0 0.7 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 0.2 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.4 PID AURORA A PATHWAY Aurora A signaling
0.0 0.3 ST G ALPHA I PATHWAY G alpha i Pathway
0.0 0.7 PID ECADHERIN STABILIZATION PATHWAY Stabilization and expansion of the E-cadherin adherens junction
0.0 0.5 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.2 PID ERBB1 RECEPTOR PROXIMAL PATHWAY EGF receptor (ErbB1) signaling pathway
0.0 0.3 PID ARF 3PATHWAY Arf1 pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.2 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.1 0.9 REACTOME ORGANIC CATION ANION ZWITTERION TRANSPORT Genes involved in Organic cation/anion/zwitterion transport
0.1 3.3 REACTOME GROWTH HORMONE RECEPTOR SIGNALING Genes involved in Growth hormone receptor signaling
0.1 0.9 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.1 2.0 REACTOME KINESINS Genes involved in Kinesins
0.1 1.3 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.1 0.6 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.1 1.2 REACTOME A TETRASACCHARIDE LINKER SEQUENCE IS REQUIRED FOR GAG SYNTHESIS Genes involved in A tetrasaccharide linker sequence is required for GAG synthesis
0.1 0.6 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.1 2.4 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions
0.1 1.6 REACTOME NEF MEDIATES DOWN MODULATION OF CELL SURFACE RECEPTORS BY RECRUITING THEM TO CLATHRIN ADAPTERS Genes involved in Nef-mediates down modulation of cell surface receptors by recruiting them to clathrin adapters
0.0 0.6 REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.0 1.3 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 1.0 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 0.2 REACTOME ADP SIGNALLING THROUGH P2RY12 Genes involved in ADP signalling through P2Y purinoceptor 12
0.0 1.2 REACTOME REGULATORY RNA PATHWAYS Genes involved in Regulatory RNA pathways
0.0 0.7 REACTOME GAP JUNCTION DEGRADATION Genes involved in Gap junction degradation
0.0 1.1 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 0.8 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.7 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.9 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 0.5 REACTOME LYSOSOME VESICLE BIOGENESIS Genes involved in Lysosome Vesicle Biogenesis
0.0 0.5 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.3 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.4 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.3 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.4 REACTOME SEMA3A PLEXIN REPULSION SIGNALING BY INHIBITING INTEGRIN ADHESION Genes involved in SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion
0.0 0.4 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.6 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.1 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 1.9 REACTOME REGULATION OF INSULIN SECRETION Genes involved in Regulation of Insulin Secretion
0.0 0.6 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.8 REACTOME THROMBOXANE SIGNALLING THROUGH TP RECEPTOR Genes involved in Thromboxane signalling through TP receptor
0.0 0.4 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.0 0.8 REACTOME PACKAGING OF TELOMERE ENDS Genes involved in Packaging Of Telomere Ends
0.0 1.1 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions
0.0 0.2 REACTOME REGULATED PROTEOLYSIS OF P75NTR Genes involved in Regulated proteolysis of p75NTR
0.0 0.5 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 0.4 REACTOME G PROTEIN BETA GAMMA SIGNALLING Genes involved in G-protein beta:gamma signalling
0.0 0.3 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION IN TLR7 8 OR 9 SIGNALING Genes involved in TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling
0.0 0.8 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.5 REACTOME PIP3 ACTIVATES AKT SIGNALING Genes involved in PIP3 activates AKT signaling
0.0 0.2 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.3 REACTOME PHOSPHORYLATION OF THE APC C Genes involved in Phosphorylation of the APC/C
0.0 0.7 REACTOME BMAL1 CLOCK NPAS2 ACTIVATES CIRCADIAN EXPRESSION Genes involved in BMAL1:CLOCK/NPAS2 Activates Circadian Expression
0.0 0.1 REACTOME OPIOID SIGNALLING Genes involved in Opioid Signalling
0.0 0.8 REACTOME ASPARAGINE N LINKED GLYCOSYLATION Genes involved in Asparagine N-linked glycosylation