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2D miR_HR1_12
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Results for Elf5
Z-value: 1.63
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Transcription factors associated with Elf5
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Elf5 | mm10_v2_chr2_+_103411682_103411696 | -0.67 | 1.7e-02 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chr9_+_110476985 Show fit | 3.14 |
ENSMUST00000084948.4
ENSMUST00000061155.6 ENSMUST00000140686.1 ENSMUST00000084952.5 |
kinesin family member 9 |
|
| chr1_+_16688405 Show fit | 3.14 |
ENSMUST00000026881.4
|
lymphocyte antigen 96 |
|
| chr2_+_180725263 Show fit | 2.67 |
ENSMUST00000094218.3
|
solute carrier family 17, member 9 |
|
| chr11_+_70647258 Show fit | 2.65 |
ENSMUST00000037534.7
|
ring finger protein 167 |
|
| chr11_-_109722214 Show fit | 2.27 |
ENSMUST00000020938.7
|
family with sequence similarity 20, member A |
|
| chr10_-_83648713 Show fit | 2.19 |
ENSMUST00000020500.7
|
adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2 |
|
| chr7_-_101864093 Show fit | 2.13 |
ENSMUST00000106981.1
|
folate receptor 1 (adult) |
|
| chr11_+_68556186 Show fit | 1.93 |
ENSMUST00000053211.6
|
major facilitator superfamily domain containing 6-like |
|
| chr3_-_137981523 Show fit | 1.92 |
ENSMUST00000136613.1
ENSMUST00000029806.6 |
dual adaptor for phosphotyrosine and 3-phosphoinositides 1 |
|
| chr9_-_105395237 Show fit | 1.91 |
ENSMUST00000140851.1
|
NIMA (never in mitosis gene a)-related expressed kinase 11 |
Network of associatons between targets according to the STRING database.
First level regulatory network of Elf5
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 5.6 | GO:0006891 | intra-Golgi vesicle-mediated transport(GO:0006891) |
| 0.1 | 4.3 | GO:0006888 | ER to Golgi vesicle-mediated transport(GO:0006888) |
| 0.8 | 4.2 | GO:1904721 | regulation of mRNA cleavage(GO:0031437) negative regulation of mRNA cleavage(GO:0031438) regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904720) negative regulation of mRNA endonucleolytic cleavage involved in unfolded protein response(GO:1904721) |
| 0.2 | 3.7 | GO:0016558 | protein import into peroxisome matrix(GO:0016558) |
| 0.1 | 3.6 | GO:0006506 | GPI anchor biosynthetic process(GO:0006506) |
| 0.6 | 3.2 | GO:0033277 | abortive mitotic cell cycle(GO:0033277) |
| 0.5 | 3.1 | GO:0032497 | detection of lipopolysaccharide(GO:0032497) |
| 0.2 | 3.1 | GO:0060363 | cranial suture morphogenesis(GO:0060363) |
| 0.3 | 3.0 | GO:0071569 | protein ufmylation(GO:0071569) |
| 0.1 | 2.9 | GO:0071577 | zinc II ion transmembrane transport(GO:0071577) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 10.7 | GO:0005783 | endoplasmic reticulum(GO:0005783) |
| 0.0 | 7.6 | GO:0005764 | lytic vacuole(GO:0000323) lysosome(GO:0005764) |
| 0.0 | 7.5 | GO:0005773 | vacuole(GO:0005773) |
| 0.0 | 6.9 | GO:0005789 | endoplasmic reticulum membrane(GO:0005789) |
| 0.0 | 5.5 | GO:0031227 | intrinsic component of endoplasmic reticulum membrane(GO:0031227) |
| 0.0 | 5.0 | GO:0030133 | transport vesicle(GO:0030133) |
| 0.1 | 4.6 | GO:0005776 | autophagosome(GO:0005776) |
| 0.6 | 4.0 | GO:0046696 | lipopolysaccharide receptor complex(GO:0046696) |
| 0.3 | 3.9 | GO:0017119 | Golgi transport complex(GO:0017119) |
| 0.1 | 3.4 | GO:0070971 | endoplasmic reticulum exit site(GO:0070971) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 8.0 | GO:0004842 | ubiquitin-protein transferase activity(GO:0004842) |
| 0.1 | 6.9 | GO:0019905 | syntaxin binding(GO:0019905) |
| 0.0 | 5.7 | GO:0017137 | Rab GTPase binding(GO:0017137) |
| 0.7 | 4.2 | GO:0060698 | endoribonuclease inhibitor activity(GO:0060698) |
| 0.1 | 3.6 | GO:0005385 | zinc ion transmembrane transporter activity(GO:0005385) |
| 0.4 | 3.3 | GO:0019198 | transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198) |
| 0.1 | 3.3 | GO:0080025 | phosphatidylinositol-3,5-bisphosphate binding(GO:0080025) |
| 0.6 | 3.1 | GO:0001875 | lipopolysaccharide receptor activity(GO:0001875) |
| 0.1 | 3.0 | GO:0004715 | non-membrane spanning protein tyrosine kinase activity(GO:0004715) |
| 0.0 | 2.7 | GO:0048306 | calcium-dependent protein binding(GO:0048306) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 5.2 | PID ERBB1 RECEPTOR PROXIMAL PATHWAY | EGF receptor (ErbB1) signaling pathway |
| 0.1 | 4.3 | PID TOLL ENDOGENOUS PATHWAY | Endogenous TLR signaling |
| 0.0 | 4.2 | NABA ECM REGULATORS | Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix |
| 0.1 | 2.6 | PID HIV NEF PATHWAY | HIV-1 Nef: Negative effector of Fas and TNF-alpha |
| 0.1 | 2.4 | PID DNA PK PATHWAY | DNA-PK pathway in nonhomologous end joining |
| 0.0 | 2.4 | PID P38 ALPHA BETA DOWNSTREAM PATHWAY | Signaling mediated by p38-alpha and p38-beta |
| 0.1 | 2.2 | ST G ALPHA S PATHWAY | G alpha s Pathway |
| 0.0 | 2.2 | PID IL2 1PATHWAY | IL2-mediated signaling events |
| 0.1 | 1.8 | PID ARF 3PATHWAY | Arf1 pathway |
| 0.1 | 1.7 | PID ERBB2 ERBB3 PATHWAY | ErbB2/ErbB3 signaling events |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 6.9 | REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S | Genes involved in Activation of Chaperone Genes by XBP1(S) |
| 0.3 | 5.2 | REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS | Genes involved in Signal regulatory protein (SIRP) family interactions |
| 0.1 | 3.9 | REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT | Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT) |
| 0.1 | 3.6 | REACTOME TIGHT JUNCTION INTERACTIONS | Genes involved in Tight junction interactions |
| 0.2 | 3.0 | REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP | Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) |
| 0.2 | 2.6 | REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 | Genes involved in IKK complex recruitment mediated by RIP1 |
| 0.1 | 2.6 | REACTOME GABA SYNTHESIS RELEASE REUPTAKE AND DEGRADATION | Genes involved in GABA synthesis, release, reuptake and degradation |
| 0.2 | 2.5 | REACTOME COPI MEDIATED TRANSPORT | Genes involved in COPI Mediated Transport |
| 0.0 | 2.5 | REACTOME PROTEIN FOLDING | Genes involved in Protein folding |
| 0.2 | 2.4 | REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK | Genes involved in Regulation of Rheb GTPase activity by AMPK |