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2D miR_HR1_12
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Results for Foxj3_Tbl1xr1
Z-value: 1.46
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Transcription factors associated with Foxj3_Tbl1xr1
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Tbl1xr1 | mm10_v2_chr3_+_22076644_22076681 | 0.50 | 1.0e-01 | Click! |
| Foxj3 | mm10_v2_chr4_+_119539716_119539779 | 0.30 | 3.5e-01 | Click! |
Network of associatons between targets according to the STRING database.
First level regulatory network of Foxj3_Tbl1xr1
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 4.0 | GO:0006910 | phagocytosis, recognition(GO:0006910) |
| 0.3 | 3.7 | GO:0051988 | regulation of attachment of spindle microtubules to kinetochore(GO:0051988) |
| 0.6 | 3.4 | GO:0060523 | prostate epithelial cord elongation(GO:0060523) |
| 0.1 | 3.0 | GO:0042274 | ribosomal small subunit biogenesis(GO:0042274) |
| 0.1 | 2.8 | GO:0008608 | attachment of spindle microtubules to kinetochore(GO:0008608) |
| 0.1 | 2.5 | GO:0006978 | DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator(GO:0006978) |
| 0.8 | 2.4 | GO:1990523 | bone regeneration(GO:1990523) |
| 0.4 | 2.4 | GO:0051987 | positive regulation of attachment of spindle microtubules to kinetochore(GO:0051987) |
| 0.1 | 2.3 | GO:0032543 | mitochondrial translation(GO:0032543) |
| 0.4 | 2.2 | GO:2000473 | regulation of hematopoietic stem cell migration(GO:2000471) positive regulation of hematopoietic stem cell migration(GO:2000473) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 8.2 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
| 0.5 | 5.2 | GO:0042571 | immunoglobulin complex, circulating(GO:0042571) |
| 0.0 | 5.2 | GO:0005813 | centrosome(GO:0005813) |
| 0.4 | 5.1 | GO:0000940 | condensed chromosome outer kinetochore(GO:0000940) |
| 0.1 | 4.4 | GO:0044391 | ribosomal subunit(GO:0044391) |
| 0.1 | 4.1 | GO:0000776 | kinetochore(GO:0000776) |
| 0.1 | 4.0 | GO:0035371 | microtubule plus-end(GO:0035371) |
| 0.1 | 3.7 | GO:0015935 | small ribosomal subunit(GO:0015935) cytosolic small ribosomal subunit(GO:0022627) |
| 0.0 | 3.6 | GO:0000793 | condensed chromosome(GO:0000793) |
| 0.0 | 3.2 | GO:0001650 | fibrillar center(GO:0001650) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 13.8 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
| 0.3 | 5.3 | GO:0034987 | immunoglobulin receptor binding(GO:0034987) |
| 0.1 | 3.7 | GO:0003777 | microtubule motor activity(GO:0003777) |
| 0.0 | 3.3 | GO:0008017 | microtubule binding(GO:0008017) |
| 1.1 | 3.2 | GO:0031798 | type 1 metabotropic glutamate receptor binding(GO:0031798) |
| 0.1 | 3.2 | GO:0003743 | translation initiation factor activity(GO:0003743) |
| 0.0 | 3.2 | GO:0101005 | thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005) |
| 0.5 | 2.9 | GO:0010997 | anaphase-promoting complex binding(GO:0010997) |
| 0.3 | 2.9 | GO:0035174 | histone serine kinase activity(GO:0035174) |
| 0.2 | 2.4 | GO:0003688 | DNA replication origin binding(GO:0003688) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 11.6 | PID PLK1 PATHWAY | PLK1 signaling events |
| 0.2 | 7.3 | PID AURORA B PATHWAY | Aurora B signaling |
| 0.1 | 4.9 | PID FOXM1 PATHWAY | FOXM1 transcription factor network |
| 0.0 | 4.6 | PID MYC ACTIV PATHWAY | Validated targets of C-MYC transcriptional activation |
| 0.1 | 3.7 | PID CXCR3 PATHWAY | CXCR3-mediated signaling events |
| 0.1 | 3.5 | PID AURORA A PATHWAY | Aurora A signaling |
| 0.0 | 3.4 | PID E2F PATHWAY | E2F transcription factor network |
| 0.1 | 3.3 | PID ATR PATHWAY | ATR signaling pathway |
| 0.1 | 3.2 | PID WNT SIGNALING PATHWAY | Wnt signaling network |
| 0.1 | 2.8 | PID BARD1 PATHWAY | BARD1 signaling events |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 19.8 | REACTOME MITOTIC PROMETAPHASE | Genes involved in Mitotic Prometaphase |
| 0.1 | 12.8 | REACTOME PEPTIDE CHAIN ELONGATION | Genes involved in Peptide chain elongation |
| 0.2 | 8.7 | REACTOME ACTIVATION OF THE PRE REPLICATIVE COMPLEX | Genes involved in Activation of the pre-replicative complex |
| 0.1 | 5.3 | REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL | Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell |
| 0.1 | 4.2 | REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES | Genes involved in Chemokine receptors bind chemokines |
| 0.0 | 3.7 | REACTOME RESPIRATORY ELECTRON TRANSPORT ATP SYNTHESIS BY CHEMIOSMOTIC COUPLING AND HEAT PRODUCTION BY UNCOUPLING PROTEINS | Genes involved in Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. |
| 0.2 | 2.9 | REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS | Genes involved in Phosphorylation of CD3 and TCR zeta chains |
| 0.1 | 2.8 | REACTOME NUCLEAR SIGNALING BY ERBB4 | Genes involved in Nuclear signaling by ERBB4 |
| 0.1 | 2.7 | REACTOME FANCONI ANEMIA PATHWAY | Genes involved in Fanconi Anemia pathway |
| 0.1 | 2.3 | REACTOME LIGAND GATED ION CHANNEL TRANSPORT | Genes involved in Ligand-gated ion channel transport |