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2D miR_HR1_12
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Results for Taf1
Z-value: 2.88
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Transcription factors associated with Taf1
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Taf1 | mm10_v2_chrX_+_101532734_101532777 | 0.77 | 3.1e-03 | Click! |
Network of associatons between targets according to the STRING database.
First level regulatory network of Taf1
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 14.8 | GO:0006412 | translation(GO:0006412) |
| 0.4 | 12.6 | GO:0000027 | ribosomal large subunit assembly(GO:0000027) |
| 0.2 | 9.4 | GO:0042273 | ribosomal large subunit biogenesis(GO:0042273) |
| 0.0 | 9.2 | GO:0000375 | RNA splicing, via transesterification reactions(GO:0000375) |
| 1.1 | 9.0 | GO:0010032 | meiotic chromosome condensation(GO:0010032) |
| 1.8 | 8.9 | GO:0090521 | glomerular visceral epithelial cell migration(GO:0090521) |
| 0.6 | 7.9 | GO:0051292 | nuclear pore complex assembly(GO:0051292) |
| 0.5 | 7.9 | GO:0000920 | cell separation after cytokinesis(GO:0000920) |
| 0.5 | 7.5 | GO:2000042 | negative regulation of double-strand break repair via homologous recombination(GO:2000042) |
| 0.1 | 7.3 | GO:0042254 | ribosome biogenesis(GO:0042254) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 23.6 | GO:0005730 | nucleolus(GO:0005730) |
| 0.3 | 23.3 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
| 0.3 | 15.4 | GO:0015934 | large ribosomal subunit(GO:0015934) |
| 0.4 | 14.9 | GO:0005763 | organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763) |
| 2.9 | 14.5 | GO:0044611 | nuclear pore inner ring(GO:0044611) |
| 0.3 | 12.6 | GO:0022627 | cytosolic small ribosomal subunit(GO:0022627) |
| 0.2 | 11.9 | GO:0005871 | kinesin complex(GO:0005871) |
| 1.0 | 9.0 | GO:0000796 | condensin complex(GO:0000796) |
| 0.1 | 7.9 | GO:0044452 | nucleolar part(GO:0044452) |
| 0.4 | 7.5 | GO:0097431 | mitotic spindle pole(GO:0097431) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.3 | 59.8 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
| 0.2 | 18.4 | GO:0003777 | microtubule motor activity(GO:0003777) |
| 0.7 | 16.8 | GO:0017056 | structural constituent of nuclear pore(GO:0017056) |
| 0.2 | 11.5 | GO:0003743 | translation initiation factor activity(GO:0003743) |
| 0.1 | 7.1 | GO:0005200 | structural constituent of cytoskeleton(GO:0005200) |
| 0.0 | 6.1 | GO:0008017 | microtubule binding(GO:0008017) |
| 0.9 | 6.0 | GO:0034513 | box H/ACA snoRNA binding(GO:0034513) |
| 0.5 | 6.0 | GO:0008097 | 5S rRNA binding(GO:0008097) |
| 0.2 | 5.4 | GO:0008143 | poly(A) binding(GO:0008143) |
| 0.2 | 5.0 | GO:0003746 | translation elongation factor activity(GO:0003746) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.5 | 25.8 | PID AURORA B PATHWAY | Aurora B signaling |
| 0.1 | 8.8 | PID MTOR 4PATHWAY | mTOR signaling pathway |
| 0.1 | 6.9 | PID TELOMERASE PATHWAY | Regulation of Telomerase |
| 0.2 | 6.5 | PID TRAIL PATHWAY | TRAIL signaling pathway |
| 0.1 | 5.4 | PID BARD1 PATHWAY | BARD1 signaling events |
| 0.1 | 4.7 | PID CASPASE PATHWAY | Caspase cascade in apoptosis |
| 0.1 | 4.7 | PID E2F PATHWAY | E2F transcription factor network |
| 0.1 | 4.3 | PID CERAMIDE PATHWAY | Ceramide signaling pathway |
| 0.0 | 3.7 | PID MYC ACTIV PATHWAY | Validated targets of C-MYC transcriptional activation |
| 0.2 | 3.2 | PID RANBP2 PATHWAY | Sumoylation by RanBP2 regulates transcriptional repression |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.4 | 39.5 | REACTOME PEPTIDE CHAIN ELONGATION | Genes involved in Peptide chain elongation |
| 0.4 | 21.0 | REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE | Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere |
| 0.5 | 16.8 | REACTOME NEP NS2 INTERACTS WITH THE CELLULAR EXPORT MACHINERY | Genes involved in NEP/NS2 Interacts with the Cellular Export Machinery |
| 0.2 | 14.0 | REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES | Genes involved in Loss of Nlp from mitotic centrosomes |
| 0.4 | 12.1 | REACTOME KINESINS | Genes involved in Kinesins |
| 0.1 | 10.6 | REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 | Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 |
| 0.1 | 10.2 | REACTOME MITOTIC PROMETAPHASE | Genes involved in Mitotic Prometaphase |
| 0.2 | 8.0 | REACTOME MITOCHONDRIAL PROTEIN IMPORT | Genes involved in Mitochondrial Protein Import |
| 0.1 | 7.4 | REACTOME RESPIRATORY ELECTRON TRANSPORT | Genes involved in Respiratory electron transport |
| 0.2 | 7.1 | REACTOME CREB PHOSPHORYLATION THROUGH THE ACTIVATION OF RAS | Genes involved in CREB phosphorylation through the activation of Ras |