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2D miR_HR1_12
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Results for Zbtb16
Z-value: 1.27
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Transcription factors associated with Zbtb16
Activity-expression correlation:
| Gene | Promoter | Pearson corr. coef. | P-value | Plot |
|---|---|---|---|---|
| Zbtb16 | mm10_v2_chr9_-_48835932_48835962 | 0.30 | 3.5e-01 | Click! |
| Promoter | Log-likelihood | Transcript | Gene | Gene Info |
|---|---|---|---|---|
| chrY_+_90785442 Show fit | 4.03 |
ENSMUST00000177591.1
ENSMUST00000177671.1 ENSMUST00000179077.1 |
erythroid differentiation regulator 1 |
|
| chr4_+_44300876 Show fit | 3.52 |
ENSMUST00000045607.5
|
maternal embryonic leucine zipper kinase |
|
| chr4_-_117178726 Show fit | 3.42 |
ENSMUST00000153953.1
ENSMUST00000106436.1 |
kinesin family member 2C |
|
| chrX_-_97377190 Show fit | 2.67 |
ENSMUST00000037353.3
|
ectodysplasin A2 receptor |
|
| chr11_+_69045640 Show fit | 2.61 |
ENSMUST00000108666.1
ENSMUST00000021277.5 |
aurora kinase B |
|
| chrX_-_97377150 Show fit | 2.07 |
ENSMUST00000113832.1
|
ectodysplasin A2 receptor |
|
| chr14_-_65833963 Show fit | 1.92 |
ENSMUST00000022613.9
|
establishment of cohesion 1 homolog 2 (S. cerevisiae) |
|
| chr5_+_110330697 Show fit | 1.89 |
ENSMUST00000112481.1
|
polymerase (DNA directed), epsilon |
|
| chr4_-_116821501 Show fit | 1.47 |
ENSMUST00000055436.3
|
4-hydroxyphenylpyruvate dioxygenase-like |
|
| chr4_+_107367757 Show fit | 1.20 |
ENSMUST00000139560.1
|
NDC1 transmembrane nucleoporin |
Network of associatons between targets according to the STRING database.
First level regulatory network of Zbtb16
Gene Ontology Analysis
Gene overrepresentation in biological process category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 4.7 | GO:0035019 | somatic stem cell population maintenance(GO:0035019) |
| 0.0 | 4.5 | GO:0072332 | intrinsic apoptotic signaling pathway by p53 class mediator(GO:0072332) |
| 0.1 | 3.5 | GO:0008631 | intrinsic apoptotic signaling pathway in response to oxidative stress(GO:0008631) |
| 0.7 | 3.4 | GO:0030951 | establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951) |
| 0.9 | 2.6 | GO:0043988 | histone H3-S28 phosphorylation(GO:0043988) |
| 0.1 | 2.3 | GO:0030488 | tRNA methylation(GO:0030488) |
| 0.6 | 1.9 | GO:0045004 | DNA replication proofreading(GO:0045004) |
| 0.4 | 1.9 | GO:0034421 | post-translational protein acetylation(GO:0034421) |
| 0.0 | 1.5 | GO:0009072 | aromatic amino acid family metabolic process(GO:0009072) |
| 0.1 | 1.2 | GO:0051292 | nuclear pore complex assembly(GO:0051292) |
Gene overrepresentation in cellular component category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.0 | 4.2 | GO:0005938 | cell cortex(GO:0005938) |
| 0.1 | 3.4 | GO:0035371 | microtubule plus-end(GO:0035371) |
| 0.4 | 2.6 | GO:0032133 | chromosome passenger complex(GO:0032133) |
| 0.4 | 1.9 | GO:0008622 | epsilon DNA polymerase complex(GO:0008622) |
| 0.1 | 1.9 | GO:0031618 | nuclear pericentric heterochromatin(GO:0031618) |
| 0.0 | 1.8 | GO:0022625 | cytosolic large ribosomal subunit(GO:0022625) |
| 0.0 | 1.7 | GO:0005643 | nuclear pore(GO:0005643) |
| 0.3 | 1.0 | GO:0071001 | U4/U6 snRNP(GO:0071001) |
| 0.1 | 0.9 | GO:0019815 | B cell receptor complex(GO:0019815) |
| 0.1 | 0.9 | GO:0046581 | intercellular canaliculus(GO:0046581) |
Gene overrepresentation in molecular function category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.2 | 3.4 | GO:0051010 | microtubule plus-end binding(GO:0051010) |
| 0.1 | 3.3 | GO:0004715 | non-membrane spanning protein tyrosine kinase activity(GO:0004715) |
| 0.3 | 2.6 | GO:0035174 | histone serine kinase activity(GO:0035174) |
| 0.3 | 2.2 | GO:0009019 | tRNA (guanine-N1-)-methyltransferase activity(GO:0009019) |
| 0.3 | 1.9 | GO:0004468 | lysine N-acetyltransferase activity, acting on acetyl phosphate as donor(GO:0004468) |
| 0.2 | 1.9 | GO:0008310 | single-stranded DNA 3'-5' exodeoxyribonuclease activity(GO:0008310) |
| 0.0 | 1.8 | GO:0003735 | structural constituent of ribosome(GO:0003735) |
| 0.1 | 1.5 | GO:0016702 | oxidoreductase activity, acting on single donors with incorporation of molecular oxygen, incorporation of two atoms of oxygen(GO:0016702) |
| 0.0 | 1.1 | GO:0017056 | structural constituent of nuclear pore(GO:0017056) |
| 0.0 | 1.1 | GO:1990782 | protein tyrosine kinase binding(GO:1990782) |
Gene overrepresentation in curated gene sets: canonical pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 6.0 | PID AURORA B PATHWAY | Aurora B signaling |
| 0.0 | 0.9 | PID NFKAPPAB ATYPICAL PATHWAY | Atypical NF-kappaB pathway |
| 0.0 | 0.7 | PID IL12 STAT4 PATHWAY | IL12 signaling mediated by STAT4 |
| 0.0 | 0.7 | PID UPA UPAR PATHWAY | Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling |
| 0.0 | 0.7 | PID RAC1 PATHWAY | RAC1 signaling pathway |
| 0.0 | 0.4 | PID ARF6 DOWNSTREAM PATHWAY | Arf6 downstream pathway |
| 0.0 | 0.3 | PID SMAD2 3PATHWAY | Regulation of cytoplasmic and nuclear SMAD2/3 signaling |
Gene overrepresentation in curated gene sets: REACTOME pathways category:
| Log-likelihood per target | Total log-likelihood | Term | Description |
|---|---|---|---|
| 0.1 | 3.4 | REACTOME KINESINS | Genes involved in Kinesins |
| 0.0 | 2.6 | REACTOME APC C CDH1 MEDIATED DEGRADATION OF CDC20 AND OTHER APC C CDH1 TARGETED PROTEINS IN LATE MITOSIS EARLY G1 | Genes involved in APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1 |
| 0.0 | 2.4 | REACTOME PEPTIDE CHAIN ELONGATION | Genes involved in Peptide chain elongation |
| 0.1 | 1.9 | REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER | Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER |
| 0.1 | 0.9 | REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS | Genes involved in Purine ribonucleoside monophosphate biosynthesis |
| 0.0 | 0.9 | REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL | Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell |
| 0.0 | 0.8 | REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS | Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis |
| 0.1 | 0.7 | REACTOME TRANSLOCATION OF ZAP 70 TO IMMUNOLOGICAL SYNAPSE | Genes involved in Translocation of ZAP-70 to Immunological synapse |
| 0.0 | 0.7 | REACTOME REGULATION OF SIGNALING BY CBL | Genes involved in Regulation of signaling by CBL |
| 0.1 | 0.6 | REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY | Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway |