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avrg: GFI1 WT vs 36n/n vs KD

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Results for Alx4

Z-value: 1.23

Motif logo

Transcription factors associated with Alx4

Gene Symbol Gene ID Gene Info
ENSMUSG00000040310.13 aristaless-like homeobox 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Alx4mm39_v1_chr2_+_93472657_93472733-0.875.6e-02Click!

Activity profile of Alx4 motif

Sorted Z-values of Alx4 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr12_-_75678092 1.49 ENSMUST00000238938.2
ribosomal protein, large P2, pseudogene 1
chr5_-_138169253 1.41 ENSMUST00000139983.8
minichromosome maintenance complex component 7
chr11_+_87684299 1.20 ENSMUST00000020779.11
myeloperoxidase
chr3_+_142326363 1.09 ENSMUST00000165774.8
guanylate binding protein 2
chr11_+_58062467 0.95 ENSMUST00000020820.2
mitochondrial ribosomal protein L22
chr5_-_138169509 0.87 ENSMUST00000153867.8
minichromosome maintenance complex component 7
chr13_-_100922910 0.76 ENSMUST00000174038.2
ENSMUST00000091295.14
ENSMUST00000072119.15
cyclin B1
chr8_+_85415935 0.74 ENSMUST00000125370.10
ENSMUST00000175784.2
tRNA methyltransferase 1
chr15_-_79658608 0.73 ENSMUST00000229644.2
ENSMUST00000023055.8
dynein, axonemal, light chain 4
chr14_-_45626237 0.70 ENSMUST00000227865.2
ENSMUST00000226856.2
ENSMUST00000226276.2
ENSMUST00000046191.9
glucosamine-phosphate N-acetyltransferase 1
chr8_-_4829519 0.68 ENSMUST00000022945.9
Shc SH2-domain binding protein 1
chr8_+_31640332 0.67 ENSMUST00000209851.2
ENSMUST00000098842.3
ENSMUST00000210129.2
TELO2 interacting protein 2
chr7_+_37882642 0.63 ENSMUST00000178207.10
ENSMUST00000179525.10
RIKEN cDNA 1600014C10 gene
chr19_-_24178000 0.60 ENSMUST00000233658.3
tight junction protein 2
chr8_+_85415876 0.59 ENSMUST00000109767.9
ENSMUST00000177084.8
ENSMUST00000109768.9
ENSMUST00000152301.9
ENSMUST00000177423.8
tRNA methyltransferase 1
chr9_-_14292453 0.59 ENSMUST00000167549.2
endonuclease domain containing 1
chr8_-_85389470 0.58 ENSMUST00000060427.6
immediate early response 2
chr3_+_89366425 0.57 ENSMUST00000029564.12
phosphomevalonate kinase
chr1_-_160898181 0.57 ENSMUST00000035430.4
aspartyl-tRNA synthetase 2 (mitochondrial)
chrM_+_8603 0.57 ENSMUST00000082409.1
mitochondrially encoded cytochrome c oxidase III
chr2_-_29677634 0.56 ENSMUST00000177467.8
ENSMUST00000113807.10
TruB pseudouridine (psi) synthase family member 2
chr12_-_80690573 0.55 ENSMUST00000166931.2
ENSMUST00000218364.2
ERH mRNA splicing and mitosis factor
chr5_-_65855511 0.54 ENSMUST00000201948.4
PDS5 cohesin associated factor A
chr19_+_41921903 0.54 ENSMUST00000224258.2
ENSMUST00000026154.9
ENSMUST00000224896.2
zinc finger, DHHC domain containing 16
chr2_-_144112700 0.53 ENSMUST00000110030.10
sorting nexin 5
chr11_-_58059293 0.53 ENSMUST00000172035.8
ENSMUST00000035604.13
ENSMUST00000102711.9
gem nuclear organelle associated protein 5
chr9_+_21634779 0.52 ENSMUST00000034713.9
low density lipoprotein receptor
chr11_+_69729340 0.52 ENSMUST00000133967.8
ENSMUST00000094065.5
transmembrane protein 256
chr11_+_94632608 0.51 ENSMUST00000021240.7
ENSMUST00000188741.2
cell division cycle 34B
chr12_+_117807224 0.50 ENSMUST00000021592.16
cell division cycle associated 7 like
chr9_+_73009680 0.49 ENSMUST00000034737.13
ENSMUST00000173734.9
ENSMUST00000167514.2
ENSMUST00000174203.3
KH domain containing 3, subcortical maternal complex member
predicted gene 20509
chr2_-_131021905 0.49 ENSMUST00000089510.5
centromere protein B
chr2_+_174169351 0.49 ENSMUST00000124935.8
GNAS (guanine nucleotide binding protein, alpha stimulating) complex locus
chr6_-_129449739 0.48 ENSMUST00000112076.9
ENSMUST00000184581.3
C-type lectin domain family 7, member a
chr4_-_154721288 0.48 ENSMUST00000030902.13
ENSMUST00000105637.8
ENSMUST00000070313.14
ENSMUST00000105636.8
ENSMUST00000105638.9
ENSMUST00000097759.9
ENSMUST00000124771.2
PR domain containing 16
chr10_+_128173603 0.48 ENSMUST00000005826.9
citrate synthase
chr15_-_79658584 0.48 ENSMUST00000069877.12
dynein, axonemal, light chain 4
chr18_-_64649497 0.46 ENSMUST00000237351.2
ENSMUST00000236186.2
ENSMUST00000235325.2
asparaginyl-tRNA synthetase
chr4_-_136329953 0.44 ENSMUST00000105847.8
ENSMUST00000116273.9
lysine (K)-specific demethylase 1A
chr14_+_62529924 0.43 ENSMUST00000166879.8
ribonuclease H2, subunit B
chr7_-_110673269 0.43 ENSMUST00000163014.2
eukaryotic translation initiation factor 4, gamma 2
chr7_+_37883074 0.43 ENSMUST00000178876.10
RIKEN cDNA 1600014C10 gene
chr15_+_100202021 0.43 ENSMUST00000230472.2
methyltransferase like 7A1
chr12_+_10440755 0.43 ENSMUST00000020947.7
retinol dehydrogenase 14 (all-trans and 9-cis)
chr10_-_30076543 0.42 ENSMUST00000099985.6
centromere protein W
chr10_-_37014859 0.42 ENSMUST00000092584.6
myristoylated alanine rich protein kinase C substrate
chr12_-_79237722 0.41 ENSMUST00000085254.7
retinol dehydrogenase 11
chr10_-_128640232 0.41 ENSMUST00000051011.14
transmembrane protein 198b
chr15_+_100202079 0.40 ENSMUST00000230252.2
ENSMUST00000231166.2
methyltransferase like 7A1
chr5_-_151574620 0.40 ENSMUST00000038131.10
replication factor C (activator 1) 3
chr18_-_10030017 0.39 ENSMUST00000116669.2
ENSMUST00000092096.14
ubiquitin specific peptidase 14
chr4_+_43493344 0.39 ENSMUST00000030181.12
ENSMUST00000107922.3
coiled-coil domain containing 107
chr4_-_135714465 0.39 ENSMUST00000105851.9
PITH (C-terminal proteasome-interacting domain of thioredoxin-like) domain containing 1
chr19_-_44095840 0.38 ENSMUST00000119591.2
ENSMUST00000026217.11
conserved helix-loop-helix ubiquitous kinase
chr9_+_98873831 0.38 ENSMUST00000185472.2
Fas apoptotic inhibitory molecule
chr3_+_89366632 0.38 ENSMUST00000107410.8
phosphomevalonate kinase
chr1_+_160898283 0.37 ENSMUST00000028035.14
ENSMUST00000111620.10
ENSMUST00000111618.8
centromere protein L
chr9_-_22028370 0.37 ENSMUST00000213233.2
ELF1 homolog, elongation factor 1
chr1_+_190660689 0.37 ENSMUST00000066632.14
ENSMUST00000110899.7
angel homolog 2
chr11_-_4045343 0.36 ENSMUST00000004868.6
mitochondrial fission process 1
chrM_+_9459 0.36 ENSMUST00000082411.1
mitochondrially encoded NADH dehydrogenase 3
chrX_-_105264751 0.35 ENSMUST00000113495.9
TATA-box binding protein associated factor 9B
chr9_+_65368207 0.35 ENSMUST00000034955.8
ENSMUST00000213957.2
SPG21, maspardin
chr6_+_11926757 0.35 ENSMUST00000133776.2
PHD finger protein 14
chr1_+_87983099 0.34 ENSMUST00000138182.8
ENSMUST00000113142.10
UDP glycosyltransferase 1 family, polypeptide A10
chr8_+_107757847 0.34 ENSMUST00000034388.10
vacuolar protein sorting 4A
chr11_-_87249837 0.33 ENSMUST00000055438.5
protein phosphatase 1E (PP2C domain containing)
chr7_-_24423715 0.33 ENSMUST00000081657.6
Ly6/PLAUR domain containing 11
chr10_+_80003612 0.33 ENSMUST00000105365.9
cold inducible RNA binding protein
chr12_-_102724931 0.33 ENSMUST00000174651.2
predicted gene 20604
chr10_-_9776823 0.33 ENSMUST00000141722.8
syntaxin binding protein 5 (tomosyn)
chr7_-_121700958 0.33 ENSMUST00000139456.2
ENSMUST00000106471.9
ENSMUST00000123296.8
ENSMUST00000033157.10
NADH:ubiquinone oxidoreductase subunit AB1
chr14_-_104760051 0.33 ENSMUST00000022716.4
ENSMUST00000228448.2
ENSMUST00000227640.2
ORC ubiquitin ligase 1
chr6_+_137731599 0.33 ENSMUST00000204356.2
deoxyribose-phosphate aldolase (putative)
chr15_+_100659622 0.32 ENSMUST00000023776.13
solute carrier family 4 (anion exchanger), member 8
chr1_-_88205233 0.32 ENSMUST00000065420.12
ENSMUST00000054674.15
Holliday junction recognition protein
chr7_+_45219766 0.32 ENSMUST00000120864.10
branched chain aminotransferase 2, mitochondrial
chr6_+_137731526 0.32 ENSMUST00000203216.3
ENSMUST00000087675.9
ENSMUST00000203693.3
deoxyribose-phosphate aldolase (putative)
chr14_+_55797443 0.32 ENSMUST00000117236.8
DDB1 and CUL4 associated factor 11
chr6_-_148847854 0.31 ENSMUST00000139355.8
ENSMUST00000146457.2
ENSMUST00000054080.15
SIN3-HDAC complex associated factor
chrX_-_94488394 0.31 ENSMUST00000084535.6
APC membrane recruitment 1
chr1_-_185061525 0.31 ENSMUST00000027921.11
ENSMUST00000110975.8
ENSMUST00000110974.4
isoleucine-tRNA synthetase 2, mitochondrial
chr11_+_106107752 0.31 ENSMUST00000021046.6
DEAD box helicase 42
chr3_+_96552895 0.31 ENSMUST00000119365.8
ENSMUST00000029744.6
integrin, alpha 10
chrX_-_133012600 0.30 ENSMUST00000033610.13
NADPH oxidase 1
chr18_+_37898633 0.30 ENSMUST00000044851.8
protocadherin gamma subfamily A, 12
chr11_-_79853200 0.30 ENSMUST00000108241.8
ENSMUST00000043152.6
UTP6 small subunit processome component
chr2_-_126342551 0.30 ENSMUST00000129187.2
ATPase, class I, type 8B, member 4
chr18_-_57108405 0.30 ENSMUST00000139243.9
ENSMUST00000025488.15
RIKEN cDNA C330018D20 gene
chr16_-_10360893 0.30 ENSMUST00000184863.8
ENSMUST00000038281.6
dexamethasone-induced transcript
chr13_-_43634695 0.29 ENSMUST00000144326.4
RAN binding protein 9
chr11_-_107228382 0.29 ENSMUST00000040380.13
phosphatidylinositol transfer protein, cytoplasmic 1
chr1_+_87983189 0.29 ENSMUST00000173325.2
UDP glycosyltransferase 1 family, polypeptide A10
chr1_+_87998487 0.29 ENSMUST00000073772.5
UDP glucuronosyltransferase 1 family, polypeptide A9
chr4_-_106536063 0.29 ENSMUST00000106772.10
ENSMUST00000135676.2
ENSMUST00000026480.13
tetratricopeptide repeat domain 4
chr15_+_65682066 0.28 ENSMUST00000211878.2
EFR3 homolog A
chr1_-_171854818 0.28 ENSMUST00000138714.2
ENSMUST00000027837.13
ENSMUST00000111264.8
VANGL planar cell polarity 2
chr1_-_63215812 0.28 ENSMUST00000185847.2
ENSMUST00000185732.7
ENSMUST00000188370.7
ENSMUST00000168099.9
NADH:ubiquinone oxidoreductase core subunit S1
chr5_-_118293443 0.28 ENSMUST00000049474.9
F-box and WD-40 domain protein 8
chr4_+_102446883 0.28 ENSMUST00000097949.11
ENSMUST00000106901.2
phosphodiesterase 4B, cAMP specific
chr5_+_115417725 0.27 ENSMUST00000040421.11
coenzyme Q5 methyltransferase
chr15_+_102234802 0.27 ENSMUST00000169637.8
prefoldin 5
chr9_-_56151334 0.27 ENSMUST00000188142.7
pseudopodium-enriched atypical kinase 1
chr12_-_79054050 0.26 ENSMUST00000056660.13
ENSMUST00000174721.8
transmembrane protein 229B
chr14_-_59602859 0.26 ENSMUST00000161031.2
PHD finger protein 11D
chr11_-_106205320 0.26 ENSMUST00000167143.2
CD79B antigen
chr2_+_91376650 0.26 ENSMUST00000099716.11
ENSMUST00000046769.16
ENSMUST00000111337.3
cytoskeleton associated protein 5
chr9_-_20871081 0.26 ENSMUST00000177754.9
DNA methyltransferase (cytosine-5) 1
chr17_-_33252341 0.26 ENSMUST00000087654.5
zinc finger protein 763
chr14_-_64654397 0.26 ENSMUST00000210428.2
methionine sulfoxide reductase A
chr13_+_76727787 0.25 ENSMUST00000126960.8
ENSMUST00000109583.9
multiple C2 domains, transmembrane 1
chrX_+_133587268 0.25 ENSMUST00000124226.3
armadillo repeat containing, X-linked 4
chr7_+_126832399 0.25 ENSMUST00000056232.7
zinc finger protein 553
chr3_+_32762656 0.24 ENSMUST00000029214.14
actin-like 6A
chr5_-_23821523 0.24 ENSMUST00000088392.9
serine/arginine-rich protein specific kinase 2
chr4_-_9643636 0.24 ENSMUST00000108333.8
ENSMUST00000108334.8
ENSMUST00000108335.8
ENSMUST00000152526.8
ENSMUST00000103004.10
aspartate-beta-hydroxylase
chr12_+_80690985 0.24 ENSMUST00000219405.2
ENSMUST00000085245.7
solute carrier family 39 (zinc transporter), member 9
chr12_+_55350023 0.24 ENSMUST00000184766.8
ENSMUST00000183475.8
ENSMUST00000183654.2
protein only RNase P catalytic subunit
chr7_+_101545547 0.24 ENSMUST00000035395.14
ENSMUST00000106973.8
ENSMUST00000144207.9
anaphase promoting complex C subunit 15
chr8_-_35432783 0.24 ENSMUST00000033929.6
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
chr11_-_51497665 0.23 ENSMUST00000074669.10
ENSMUST00000101249.9
ENSMUST00000109103.4
heterogeneous nuclear ribonucleoprotein A/B
chr12_+_87204374 0.23 ENSMUST00000222222.2
glutathione transferase zeta 1 (maleylacetoacetate isomerase)
chr6_-_115014777 0.23 ENSMUST00000174848.8
ENSMUST00000032461.12
TAM41 mitochondrial translocator assembly and maintenance homolog
chr17_+_66418598 0.23 ENSMUST00000116556.4
ENSMUST00000233354.2
WASH complex subunit 1
chr11_+_109434519 0.23 ENSMUST00000106696.2
arylsulfatase G
chr1_-_78465479 0.23 ENSMUST00000190441.2
ENSMUST00000170217.8
ENSMUST00000188247.7
ENSMUST00000068333.14
phenylalanyl-tRNA synthetase, beta subunit
chr6_-_148847633 0.23 ENSMUST00000132696.8
SIN3-HDAC complex associated factor
chr18_-_36587573 0.23 ENSMUST00000025204.7
ENSMUST00000237792.2
prefoldin 1
chr18_-_64649620 0.22 ENSMUST00000025483.11
ENSMUST00000237400.2
asparaginyl-tRNA synthetase
chr2_-_87504008 0.22 ENSMUST00000213835.2
olfactory receptor 1135
chr12_+_88327305 0.22 ENSMUST00000101165.9
aarF domain containing kinase 1
chr7_-_10488291 0.22 ENSMUST00000226874.2
ENSMUST00000227003.2
ENSMUST00000228561.2
ENSMUST00000228248.2
ENSMUST00000228526.2
ENSMUST00000228098.2
ENSMUST00000227940.2
ENSMUST00000228374.2
ENSMUST00000227702.2
vomeronasal 1 receptor 71
chr7_+_101546059 0.22 ENSMUST00000143835.8
anaphase promoting complex C subunit 15
chr5_-_120750623 0.22 ENSMUST00000140554.2
ENSMUST00000031599.9
ENSMUST00000177800.8
RBPJ interacting and tubulin associated 1
chr16_+_48692976 0.21 ENSMUST00000065666.6
resistin like gamma
chr14_+_55797468 0.21 ENSMUST00000147981.2
ENSMUST00000133256.8
DDB1 and CUL4 associated factor 11
chr8_-_117809188 0.21 ENSMUST00000109093.9
ENSMUST00000098375.6
polycystic kidney disease 1 like 2
chr19_+_5012362 0.21 ENSMUST00000236917.2
mitochondrial ribosomal protein L11
chr3_-_88317601 0.21 ENSMUST00000193338.6
ENSMUST00000056370.13
polyamine-modulated factor 1
chr16_+_18655318 0.21 ENSMUST00000055413.13
ENSMUST00000123146.8
ENSMUST00000191388.2
RIKEN cDNA 2510002D24 gene
chr12_-_114012399 0.21 ENSMUST00000103468.3
immunoglobulin heavy variable V11-2
chr7_+_126575781 0.20 ENSMUST00000206450.2
ENSMUST00000205830.2
CDP-diacylglycerol--inositol 3-phosphatidyltransferase (phosphatidylinositol synthase)
chr4_+_147216495 0.20 ENSMUST00000084149.10
zinc finger protein 991
chrX_-_133501002 0.20 ENSMUST00000153024.2
galactosidase, alpha
chr16_-_35184211 0.20 ENSMUST00000043521.5
SEC22 homolog A, vesicle trafficking protein
chr17_+_66418525 0.20 ENSMUST00000072383.14
WASH complex subunit 1
chrX_+_20529137 0.20 ENSMUST00000001989.9
ubiquitin-like modifier activating enzyme 1
chr6_-_13607963 0.20 ENSMUST00000031554.9
ENSMUST00000149123.3
transmembrane protein 168
chr12_-_55349760 0.20 ENSMUST00000021410.10
protein phosphatase 2, regulatory subunit B'', gamma
chr2_-_131001916 0.20 ENSMUST00000103188.10
ENSMUST00000133602.8
ENSMUST00000028800.12
RIKEN cDNA 1700037H04 gene
chr7_+_23969822 0.19 ENSMUST00000108438.10
zinc finger protein 93
chr14_-_64654592 0.19 ENSMUST00000210363.2
methionine sulfoxide reductase A
chr17_-_56343531 0.19 ENSMUST00000233803.2
SH3-domain GRB2-like 1
chr12_+_88327391 0.19 ENSMUST00000222695.2
aarF domain containing kinase 1
chr2_-_104847360 0.19 ENSMUST00000111110.3
ENSMUST00000028592.12
eukaryotic translation initiation factor 3, subunit M
chr11_+_80074677 0.19 ENSMUST00000017839.3
ring finger protein 135
chr11_+_60428788 0.19 ENSMUST00000044250.4
alkB homolog 5, RNA demethylase
chr18_+_46730765 0.19 ENSMUST00000238168.2
ENSMUST00000078079.11
ENSMUST00000168382.2
ENSMUST00000235849.2
ENSMUST00000235973.2
ENSMUST00000235455.2
ENSMUST00000237478.2
eukaryotic translation initiation factor 1A
chr14_+_32043944 0.19 ENSMUST00000022480.8
ENSMUST00000228529.2
oxoglutarate dehydrogenase-like
chr1_-_152262425 0.19 ENSMUST00000015124.15
tRNA splicing endonuclease subunit 15
chr1_+_75498162 0.19 ENSMUST00000027414.16
ENSMUST00000113553.2
serine/threonine kinase 11 interacting protein
chr6_-_69282389 0.19 ENSMUST00000103350.3
immunoglobulin kappa variable 4-68
chr9_+_19828161 0.18 ENSMUST00000217347.2
ENSMUST00000057596.10
olfactory receptor 77
chr17_+_29493113 0.18 ENSMUST00000234326.2
ENSMUST00000235117.2
cDNA sequence BC004004
chr18_+_44960813 0.18 ENSMUST00000037763.11
YTH domain containing 2
chr14_-_66361931 0.18 ENSMUST00000070515.2
epoxide hydrolase 2, cytoplasmic
chr11_+_62442502 0.18 ENSMUST00000136938.2
ubiquitin B
chr6_+_123239076 0.18 ENSMUST00000032240.4
C-type lectin domain family 4, member d
chr19_-_46033353 0.17 ENSMUST00000026252.14
ENSMUST00000156585.9
ENSMUST00000185355.7
ENSMUST00000152946.8
LIM domain binding 1
chr13_+_51562675 0.17 ENSMUST00000087978.5
sphingosine-1-phosphate receptor 3
chr18_+_31742565 0.17 ENSMUST00000164667.2
RIKEN cDNA B930094E09 gene
chr2_-_34716083 0.17 ENSMUST00000113077.8
ENSMUST00000028220.10
F-box and WD-40 domain protein 2
chr19_+_8713156 0.17 ENSMUST00000210512.2
ENSMUST00000049424.11
WD repeat domain 74
chr6_-_108162513 0.17 ENSMUST00000167338.8
ENSMUST00000172188.2
ENSMUST00000032191.16
sulfatase modifying factor 1
chrX_+_139857640 0.17 ENSMUST00000112971.2
autophagy related 4A, cysteine peptidase
chr17_+_79919267 0.17 ENSMUST00000223924.2
regulator of microtubule dynamics 2
chr1_-_152262339 0.16 ENSMUST00000162371.2
tRNA splicing endonuclease subunit 15
chr5_-_137834444 0.16 ENSMUST00000197586.2
paired immunoglobin-like type 2 receptor alpha
chr17_+_29493049 0.16 ENSMUST00000149405.4
cDNA sequence BC004004
chr9_+_21437440 0.16 ENSMUST00000086361.12
ENSMUST00000173769.3
cDNA sequence AB124611
chr7_+_44221791 0.16 ENSMUST00000002274.10
napsin A aspartic peptidase
chr6_-_28397997 0.16 ENSMUST00000035930.11
zinc finger protein 800
chr3_-_108469468 0.16 ENSMUST00000106622.3
transmembrane protein 167B
chr2_+_22785534 0.16 ENSMUST00000053729.14
prenyl (solanesyl) diphosphate synthase, subunit 1
chrX_+_36390430 0.16 ENSMUST00000016553.5
NFKB activating protein
chr15_+_80017315 0.15 ENSMUST00000023050.9
TGF-beta activated kinase 1/MAP3K7 binding protein 1
chr10_-_129107354 0.15 ENSMUST00000204573.3
olfactory receptor 777
chr18_+_23885390 0.15 ENSMUST00000170802.8
ENSMUST00000155708.8
ENSMUST00000118826.9
microtubule-associated protein, RP/EB family, member 2
chr14_+_19801333 0.15 ENSMUST00000022340.5
nidogen 2
chr12_-_85871281 0.15 ENSMUST00000021676.12
ENSMUST00000142331.2
ergosterol biosynthesis 28
chrX_+_139857688 0.15 ENSMUST00000239541.1
autophagy related 4A, cysteine peptidase
chr17_+_35188888 0.14 ENSMUST00000173680.2
predicted gene 20481
chr13_-_81859056 0.14 ENSMUST00000161920.2
ENSMUST00000048993.12
polymerase (RNA) III (DNA directed) polypeptide G
chr1_-_88205185 0.14 ENSMUST00000147393.2
Holliday junction recognition protein
chr2_-_86109346 0.14 ENSMUST00000217294.2
ENSMUST00000217245.2
ENSMUST00000216432.2
olfactory receptor 1051
chr1_-_63215952 0.14 ENSMUST00000185412.7
ENSMUST00000027111.15
ENSMUST00000189664.2
NADH:ubiquinone oxidoreductase core subunit S1
chr4_+_150938376 0.14 ENSMUST00000073600.9
ERBB receptor feedback inhibitor 1
chr5_-_138169476 0.14 ENSMUST00000147920.2
minichromosome maintenance complex component 7
chr2_+_32496990 0.14 ENSMUST00000095045.9
ENSMUST00000095044.10
ENSMUST00000126636.8
ST6 (alpha-N-acetyl-neuraminyl-2,3-beta-galactosyl-1,3)-N-acetylgalactosaminide alpha-2,6-sialyltransferase 6
chr11_+_114566257 0.13 ENSMUST00000045779.6
tweety family member 2

Network of associatons between targets according to the STRING database.

First level regulatory network of Alx4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0002940 tRNA N2-guanine methylation(GO:0002940)
0.4 1.2 GO:0002149 hypochlorous acid metabolic process(GO:0002148) hypochlorous acid biosynthetic process(GO:0002149)
0.2 1.2 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.2 1.0 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.2 2.4 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.2 0.8 GO:0031660 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662)
0.2 0.8 GO:0006041 glucosamine metabolic process(GO:0006041)
0.1 0.5 GO:0010899 regulation of phosphatidylcholine catabolic process(GO:0010899) receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport(GO:0090118) positive regulation of lysosomal protein catabolic process(GO:1905167)
0.1 0.6 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.1 0.3 GO:0044878 mitotic cytokinesis checkpoint(GO:0044878)
0.1 1.2 GO:2000582 regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.1 0.4 GO:0046098 guanine metabolic process(GO:0046098)
0.1 0.3 GO:0006550 isoleucine catabolic process(GO:0006550)
0.1 0.3 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
0.1 0.1 GO:0046122 purine deoxyribonucleoside metabolic process(GO:0046122)
0.1 0.4 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.1 0.3 GO:0061341 dichotomous subdivision of terminal units involved in lung branching(GO:0060448) non-canonical Wnt signaling pathway involved in heart development(GO:0061341) planar cell polarity pathway involved in heart morphogenesis(GO:0061346)
0.1 0.6 GO:2001205 negative regulation of osteoclast development(GO:2001205)
0.1 0.2 GO:0016062 adaptation of rhodopsin mediated signaling(GO:0016062) light adaption(GO:0036367)
0.1 0.2 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.1 0.2 GO:1904742 regulation of telomeric DNA binding(GO:1904742)
0.1 0.9 GO:0052696 flavonoid glucuronidation(GO:0052696) xenobiotic glucuronidation(GO:0052697)
0.1 0.5 GO:0061641 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.1 0.4 GO:0072592 oxygen metabolic process(GO:0072592)
0.1 0.4 GO:2000583 regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000583) negative regulation of platelet-derived growth factor receptor-alpha signaling pathway(GO:2000584)
0.1 0.3 GO:0090116 C-5 methylation of cytosine(GO:0090116) positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.1 0.4 GO:1904109 positive regulation of cholesterol import(GO:1904109) positive regulation of sterol import(GO:2000911)
0.1 0.2 GO:0046271 phenylpropanoid catabolic process(GO:0046271) olefin metabolic process(GO:1900673)
0.1 0.2 GO:0043973 histone H3-K4 acetylation(GO:0043973)
0.1 0.2 GO:0002408 myeloid dendritic cell chemotaxis(GO:0002408)
0.0 0.1 GO:0006696 ergosterol biosynthetic process(GO:0006696) ergosterol metabolic process(GO:0008204)
0.0 0.2 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.0 0.3 GO:0051697 protein delipidation(GO:0051697)
0.0 0.4 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.0 1.1 GO:0044406 adhesion of symbiont to host(GO:0044406)
0.0 0.3 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.0 0.3 GO:0070417 cellular response to cold(GO:0070417)
0.0 0.4 GO:0040032 post-embryonic body morphogenesis(GO:0040032)
0.0 0.2 GO:0046341 CDP-diacylglycerol metabolic process(GO:0046341)
0.0 0.2 GO:0035063 nuclear speck organization(GO:0035063)
0.0 0.1 GO:1900377 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.0 0.5 GO:1901727 positive regulation of histone deacetylase activity(GO:1901727)
0.0 0.3 GO:0009249 protein lipoylation(GO:0009249)
0.0 0.1 GO:2001200 positive regulation of dendritic cell differentiation(GO:2001200)
0.0 0.4 GO:0072642 type I interferon secretion(GO:0072641) interferon-alpha secretion(GO:0072642) regulation of interferon-alpha secretion(GO:1902739) positive regulation of interferon-alpha secretion(GO:1902741)
0.0 0.5 GO:0030853 negative regulation of granulocyte differentiation(GO:0030853)
0.0 0.2 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.0 0.2 GO:0035553 oxidative single-stranded RNA demethylation(GO:0035553)
0.0 0.3 GO:2001012 mesenchymal cell differentiation involved in kidney development(GO:0072161) mesenchymal cell differentiation involved in renal system development(GO:2001012)
0.0 1.1 GO:0051560 mitochondrial calcium ion homeostasis(GO:0051560)
0.0 0.2 GO:0006572 tyrosine catabolic process(GO:0006572)
0.0 0.2 GO:0002759 regulation of antimicrobial humoral response(GO:0002759)
0.0 0.5 GO:0090266 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.0 0.4 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.1 GO:1903243 negative regulation of cardiac muscle adaptation(GO:0010616) negative regulation of cardiac muscle hypertrophy in response to stress(GO:1903243)
0.0 0.6 GO:0001522 pseudouridine synthesis(GO:0001522)
0.0 0.3 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 0.3 GO:0016191 synaptic vesicle uncoating(GO:0016191)
0.0 0.2 GO:0038094 Fc-gamma receptor signaling pathway(GO:0038094)
0.0 0.2 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 0.3 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 0.1 GO:0038108 negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108)
0.0 0.2 GO:0006655 phosphatidylglycerol biosynthetic process(GO:0006655) cardiolipin biosynthetic process(GO:0032049)
0.0 0.4 GO:0051382 kinetochore assembly(GO:0051382)
0.0 0.3 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.4 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.0 0.1 GO:0002879 positive regulation of acute inflammatory response to non-antigenic stimulus(GO:0002879)
0.0 0.1 GO:1902962 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.0 0.1 GO:0015851 nucleobase transport(GO:0015851) pyrimidine nucleobase transport(GO:0015855)
0.0 0.3 GO:0001574 ganglioside biosynthetic process(GO:0001574)
0.0 0.1 GO:0019323 pentose catabolic process(GO:0019323)
0.0 0.5 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.5 GO:0007094 mitotic spindle assembly checkpoint(GO:0007094)
0.0 0.5 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 0.2 GO:0044829 positive regulation by host of viral genome replication(GO:0044829)
0.0 0.4 GO:0006744 ubiquinone biosynthetic process(GO:0006744)
0.0 0.7 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.0 0.2 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.0 0.4 GO:0042572 retinol metabolic process(GO:0042572)
0.0 0.5 GO:0018345 protein palmitoylation(GO:0018345)
0.0 0.4 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0 0.1 GO:0071034 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.0 0.1 GO:0021888 hypothalamus gonadotrophin-releasing hormone neuron differentiation(GO:0021886) hypothalamus gonadotrophin-releasing hormone neuron development(GO:0021888)
0.0 0.1 GO:0061718 NADH regeneration(GO:0006735) canonical glycolysis(GO:0061621) glucose catabolic process to pyruvate(GO:0061718)
0.0 0.4 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.2 GO:0043129 surfactant homeostasis(GO:0043129)
0.0 0.5 GO:0006907 pinocytosis(GO:0006907)
0.0 0.1 GO:0090168 Golgi reassembly(GO:0090168)
0.0 0.6 GO:0009060 aerobic respiration(GO:0009060)
0.0 0.5 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 0.1 GO:1903599 positive regulation of mitophagy(GO:1903599)
0.0 0.2 GO:0045602 negative regulation of endothelial cell differentiation(GO:0045602)
0.0 0.2 GO:1900017 positive regulation of cytokine production involved in inflammatory response(GO:1900017)
0.0 0.2 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.1 GO:0019532 oxalate transport(GO:0019532)
0.0 0.3 GO:0060712 spongiotrophoblast layer development(GO:0060712)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0000942 condensed nuclear chromosome outer kinetochore(GO:0000942)
0.2 0.5 GO:1990666 PCSK9-LDLR complex(GO:1990666)
0.2 2.4 GO:0042555 MCM complex(GO:0042555)
0.1 0.3 GO:0034680 integrin alpha10-beta1 complex(GO:0034680)
0.1 0.3 GO:0060187 cell pole(GO:0060187)
0.1 1.1 GO:0020005 symbiont-containing vacuole membrane(GO:0020005)
0.1 0.2 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.1 0.5 GO:0031313 extrinsic component of endosome membrane(GO:0031313)
0.1 0.4 GO:0032299 ribonuclease H2 complex(GO:0032299)
0.1 1.2 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.1 0.4 GO:0042585 germinal vesicle(GO:0042585)
0.1 0.4 GO:0005663 DNA replication factor C complex(GO:0005663)
0.1 0.3 GO:0071438 invadopodium membrane(GO:0071438)
0.1 0.5 GO:0045179 apical cortex(GO:0045179)
0.0 0.3 GO:1990393 3M complex(GO:1990393)
0.0 0.5 GO:0034719 SMN-Sm protein complex(GO:0034719)
0.0 0.3 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 0.5 GO:0034709 methylosome(GO:0034709)
0.0 0.2 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.0 0.4 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.4 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.1 GO:0030312 external encapsulating structure(GO:0030312)
0.0 0.4 GO:0071203 WASH complex(GO:0071203)
0.0 0.3 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.5 GO:0031618 nuclear pericentric heterochromatin(GO:0031618)
0.0 0.3 GO:0019815 B cell receptor complex(GO:0019815)
0.0 0.4 GO:0008385 IkappaB kinase complex(GO:0008385)
0.0 0.4 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.2 GO:0044214 spanning component of plasma membrane(GO:0044214) spanning component of membrane(GO:0089717)
0.0 0.2 GO:0032541 cortical endoplasmic reticulum(GO:0032541)
0.0 0.2 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 1.2 GO:0030286 dynein complex(GO:0030286)
0.0 0.5 GO:0000777 condensed chromosome kinetochore(GO:0000777)
0.0 1.2 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.1 GO:1990037 Lewy body core(GO:1990037)
0.0 0.1 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.0 0.5 GO:0000930 gamma-tubulin complex(GO:0000930)
0.0 0.2 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 0.6 GO:0005921 gap junction(GO:0005921)
0.0 0.3 GO:0005721 pericentric heterochromatin(GO:0005721)
0.0 0.5 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.5 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.3 GO:0005892 acetylcholine-gated channel complex(GO:0005892)
0.0 0.2 GO:0097208 alveolar lamellar body(GO:0097208)
0.0 0.2 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.2 GO:0031011 Ino80 complex(GO:0031011)
0.0 0.9 GO:0005793 endoplasmic reticulum-Golgi intermediate compartment(GO:0005793)
0.0 0.2 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 0.4 GO:0030140 trans-Golgi network transport vesicle(GO:0030140)
0.0 0.4 GO:0032588 trans-Golgi network membrane(GO:0032588)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.3 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.2 0.5 GO:0030622 U4atac snRNA binding(GO:0030622)
0.2 0.7 GO:0004816 asparagine-tRNA ligase activity(GO:0004816)
0.1 0.8 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.1 0.5 GO:0003696 satellite DNA binding(GO:0003696)
0.1 0.4 GO:0008113 peptide-methionine (S)-S-oxide reductase activity(GO:0008113)
0.1 0.3 GO:0031177 phosphopantetheine binding(GO:0031177)
0.1 0.3 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
0.1 0.4 GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.1 0.2 GO:0016034 maleylacetoacetate isomerase activity(GO:0016034)
0.1 0.2 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.1 0.2 GO:0003881 CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity(GO:0003881)
0.1 0.6 GO:0034452 dynactin binding(GO:0034452)
0.1 0.5 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.1 0.2 GO:0052692 raffinose alpha-galactosidase activity(GO:0052692)
0.1 0.5 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.1 0.2 GO:0050309 glucose-6-phosphatase activity(GO:0004346) sugar-terminal-phosphatase activity(GO:0050309)
0.1 0.4 GO:0008384 IkappaB kinase activity(GO:0008384)
0.1 0.4 GO:0004523 RNA-DNA hybrid ribonuclease activity(GO:0004523)
0.1 0.4 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.1 0.4 GO:0000213 tRNA-intron endonuclease activity(GO:0000213)
0.1 0.3 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.1 2.4 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.1 0.2 GO:1990932 5.8S rRNA binding(GO:1990932)
0.1 0.4 GO:0008106 alcohol dehydrogenase (NADP+) activity(GO:0008106)
0.1 0.3 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.0 0.2 GO:0004301 epoxide hydrolase activity(GO:0004301)
0.0 1.2 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.2 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 0.3 GO:0004084 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.0 0.2 GO:0000010 trans-hexaprenyltranstransferase activity(GO:0000010) trans-octaprenyltranstransferase activity(GO:0050347)
0.0 0.4 GO:0001075 transcription factor activity, RNA polymerase II core promoter sequence-specific binding involved in preinitiation complex assembly(GO:0001075)
0.0 0.2 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.4 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.2 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.0 0.7 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.0 0.8 GO:0008327 methyl-CpG binding(GO:0008327)
0.0 0.6 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.4 GO:0051430 corticotropin-releasing hormone receptor 1 binding(GO:0051430)
0.0 0.4 GO:0042609 CD4 receptor binding(GO:0042609)
0.0 0.3 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 0.2 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.0 0.1 GO:0019136 deoxynucleoside kinase activity(GO:0019136)
0.0 0.3 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 0.3 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.1 GO:0005174 CD40 receptor binding(GO:0005174)
0.0 0.9 GO:0015020 glucuronosyltransferase activity(GO:0015020)
0.0 0.2 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.0 0.2 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.0 0.2 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.1 GO:0008802 betaine-aldehyde dehydrogenase activity(GO:0008802)
0.0 0.5 GO:0016676 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 1.2 GO:0004601 peroxidase activity(GO:0004601)
0.0 0.5 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.2 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 0.3 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.1 GO:0015205 purine nucleobase transmembrane transporter activity(GO:0005345) pyrimidine nucleobase transmembrane transporter activity(GO:0005350) nucleobase transmembrane transporter activity(GO:0015205) glycerol channel activity(GO:0015254)
0.0 0.3 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 1.0 GO:0016776 phosphotransferase activity, phosphate group as acceptor(GO:0016776)
0.0 0.4 GO:0070628 proteasome binding(GO:0070628)
0.0 0.1 GO:0032027 myosin light chain binding(GO:0032027)
0.0 0.1 GO:0019158 fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0 0.1 GO:0008273 calcium, potassium:sodium antiporter activity(GO:0008273)
0.0 0.7 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.5 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.0 0.5 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.2 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.0 0.2 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.3 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.7 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.1 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0 0.2 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.0 0.3 GO:0017075 syntaxin-1 binding(GO:0017075)
0.0 0.1 GO:0033038 bitter taste receptor activity(GO:0033038)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.9 PID ATR PATHWAY ATR signaling pathway
0.0 1.3 PID FOXM1 PATHWAY FOXM1 transcription factor network
0.0 1.2 PID IL23 PATHWAY IL23-mediated signaling events
0.0 0.4 PID NFKAPPAB CANONICAL PATHWAY Canonical NF-kappaB pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.4 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.1 1.2 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.1 0.8 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0 0.4 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.8 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.6 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0 0.4 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 1.0 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.3 REACTOME GLUCURONIDATION Genes involved in Glucuronidation
0.0 0.6 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.0 0.4 REACTOME POL SWITCHING Genes involved in Polymerase switching
0.0 0.5 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.5 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.5 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 1.1 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.0 0.3 REACTOME GLUCOSE TRANSPORT Genes involved in Glucose transport
0.0 0.2 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 0.3 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.4 REACTOME ANTIVIRAL MECHANISM BY IFN STIMULATED GENES Genes involved in Antiviral mechanism by IFN-stimulated genes
0.0 0.3 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)