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avrg: GFI1 WT vs 36n/n vs KD

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Results for Arid5a

Z-value: 0.54

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Transcription factors associated with Arid5a

Gene Symbol Gene ID Gene Info
Arid5a
ENSMUSG00000037447.17 AT rich interactive domain 5A (MRF1-like)

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Arid5amm39_v1_chr1_+_36346824_36346850-0.464.3e-01Click!

Activity profile of Arid5a motif

Sorted Z-values of Arid5a motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr10_-_115198093 0.33 ENSMUST00000219890.2
ENSMUST00000218731.2
ENSMUST00000217887.2
ENSMUST00000092170.7
Tmem19
transmembrane protein 19
chrM_+_8603 0.33 ENSMUST00000082409.1
mt-Co3
mitochondrially encoded cytochrome c oxidase III
chr13_+_94954202 0.28 ENSMUST00000220825.2
Tbca
tubulin cofactor A
chr10_-_115197775 0.25 ENSMUST00000217848.2
Tmem19
transmembrane protein 19
chr17_-_35265702 0.23 ENSMUST00000097338.11
Msh5
mutS homolog 5
chr15_-_55421144 0.22 ENSMUST00000172387.8
Mrpl13
mitochondrial ribosomal protein L13
chrM_+_7758 0.22 ENSMUST00000082407.1
mt-Atp8
mitochondrially encoded ATP synthase 8
chr15_+_41573995 0.20 ENSMUST00000229769.2
Oxr1
oxidation resistance 1
chr3_-_146487102 0.18 ENSMUST00000005164.12
Prkacb
protein kinase, cAMP dependent, catalytic, beta
chr11_+_98689479 0.17 ENSMUST00000037930.13
Msl1
male specific lethal 1
chrM_+_7779 0.15 ENSMUST00000082408.1
mt-Atp6
mitochondrially encoded ATP synthase 6
chrX_-_133012600 0.13 ENSMUST00000033610.13
Nox1
NADPH oxidase 1
chr9_+_96140781 0.09 ENSMUST00000190104.7
ENSMUST00000179416.8
ENSMUST00000189606.7
Tfdp2
transcription factor Dp 2
chr17_-_37594351 0.05 ENSMUST00000216328.2
Olfr99
olfactory receptor 99
chr9_+_96140750 0.04 ENSMUST00000186609.7
Tfdp2
transcription factor Dp 2
chr3_+_75982890 0.02 ENSMUST00000160261.8
Fstl5
follistatin-like 5
chr5_-_87074380 0.02 ENSMUST00000031183.3
Ugt2b1
UDP glucuronosyltransferase 2 family, polypeptide B1
chr10_+_52267702 0.02 ENSMUST00000067085.7
Nepn
nephrocan
chr4_-_52919172 0.01 ENSMUST00000107667.3
ENSMUST00000213989.2
Olfr272
olfactory receptor 272
chr4_+_43384320 0.01 ENSMUST00000136360.2
Rusc2
RUN and SH3 domain containing 2
chr2_+_61876806 0.01 ENSMUST00000102735.10
Slc4a10
solute carrier family 4, sodium bicarbonate cotransporter-like, member 10
chrX_-_133012457 0.01 ENSMUST00000159259.3
ENSMUST00000113275.10
Nox1
NADPH oxidase 1
chr10_+_69370038 0.01 ENSMUST00000182439.8
ENSMUST00000092434.12
ENSMUST00000047061.13
ENSMUST00000092432.12
ENSMUST00000092431.12
ENSMUST00000054167.15
Ank3
ankyrin 3, epithelial
chr18_+_37637317 0.01 ENSMUST00000052179.8
Pcdhb20
protocadherin beta 20
chr2_+_105505823 0.01 ENSMUST00000167211.9
ENSMUST00000111083.10
Pax6
paired box 6
chr1_-_162913210 0.01 ENSMUST00000096608.5
Mroh9
maestro heat-like repeat family member 9
chr9_+_37996134 0.01 ENSMUST00000074681.2
Olfr887
olfactory receptor 887
chr1_+_133965228 0.01 ENSMUST00000162779.2
Fmod
fibromodulin
chr2_+_58644922 0.01 ENSMUST00000059102.13
Upp2
uridine phosphorylase 2
chr2_+_61876923 0.01 ENSMUST00000054484.15
Slc4a10
solute carrier family 4, sodium bicarbonate cotransporter-like, member 10
chr2_+_61876956 0.01 ENSMUST00000112480.3
Slc4a10
solute carrier family 4, sodium bicarbonate cotransporter-like, member 10
chr2_+_58645189 0.01 ENSMUST00000102755.4
ENSMUST00000230627.2
ENSMUST00000229923.2
Upp2
uridine phosphorylase 2
chr10_+_129298547 0.01 ENSMUST00000077836.3
Olfr787
olfactory receptor 787
chr2_-_111476340 0.00 ENSMUST00000119566.4
Olfr1298
olfactory receptor 1298
chr7_-_105249308 0.00 ENSMUST00000210531.2
ENSMUST00000033185.10
Hpx
hemopexin
chr2_-_79959802 0.00 ENSMUST00000102653.8
Pde1a
phosphodiesterase 1A, calmodulin-dependent
chr5_+_68189116 0.00 ENSMUST00000094715.8
Grxcr1
glutaredoxin, cysteine rich 1
chr5_-_18054702 0.00 ENSMUST00000165232.8
Cd36
CD36 molecule
chr7_-_132616977 0.00 ENSMUST00000169570.8
Ctbp2
C-terminal binding protein 2

Network of associatons between targets according to the STRING database.

First level regulatory network of Arid5a

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.0 0.1 GO:0072592 positive regulation of integrin biosynthetic process(GO:0045726) oxygen metabolic process(GO:0072592)
0.0 0.2 GO:0051026 chiasma assembly(GO:0051026)
0.0 0.2 GO:1901621 negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning(GO:1901621)
0.0 0.4 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.2 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 GO:0072487 MSL complex(GO:0072487)
0.0 0.4 GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.0 0.1 GO:0071438 invadopodium membrane(GO:0071438)
0.0 0.2 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.0 0.2 GO:0030983 mismatched DNA binding(GO:0030983)
0.0 0.2 GO:0004691 cAMP-dependent protein kinase activity(GO:0004691)
0.0 0.3 GO:0015002 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway