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avrg: GFI1 WT vs 36n/n vs KD

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Results for Atf6

Z-value: 1.69

Motif logo

Transcription factors associated with Atf6

Gene Symbol Gene ID Gene Info
ENSMUSG00000026663.7 activating transcription factor 6

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Atf6mm39_v1_chr1_-_170695328_170695354-0.771.2e-01Click!

Activity profile of Atf6 motif

Sorted Z-values of Atf6 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr2_+_80145805 1.03 ENSMUST00000028392.8
DnaJ heat shock protein family (Hsp40) member C10
chr11_-_69812016 1.01 ENSMUST00000108607.8
eukaryotic translation initiation factor 5A
chrX_-_133709733 0.98 ENSMUST00000035559.11
armadillo repeat containing, X-linked 2
chr6_+_83092476 0.97 ENSMUST00000032114.8
mannosyl-oligosaccharide glucosidase
chr3_+_104545974 0.74 ENSMUST00000046212.2
solute carrier family 16 (monocarboxylic acid transporters), member 1
chr4_-_149858694 0.73 ENSMUST00000105686.3
solute carrier family 25, member 33
chr6_+_88061464 0.60 ENSMUST00000032143.8
ribophorin I
chr6_-_124441731 0.58 ENSMUST00000008297.5
calsyntenin 3
chr19_-_41836514 0.57 ENSMUST00000059231.4
frequently rearranged in advanced T cell lymphomas 2
chr8_+_13388745 0.55 ENSMUST00000209885.2
ENSMUST00000209396.2
transcription factor Dp 1
chr4_-_43000450 0.54 ENSMUST00000030164.8
valosin containing protein
chr7_-_45116197 0.54 ENSMUST00000211195.2
ENSMUST00000210019.2
BCL2-associated X protein
chr14_+_32507920 0.54 ENSMUST00000039191.8
ENSMUST00000227060.2
ENSMUST00000228481.2
transmembrane protein 273
chr7_-_113853894 0.53 ENSMUST00000033012.9
coatomer protein complex, subunit beta 1
chr17_-_36353582 0.52 ENSMUST00000058801.15
ENSMUST00000080015.12
ENSMUST00000077960.7
histocompatibility 2, T region locus 22
chr1_-_93373145 0.51 ENSMUST00000186787.7
high density lipoprotein (HDL) binding protein
chr7_-_45116216 0.50 ENSMUST00000210392.2
ENSMUST00000211365.2
BCL2-associated X protein
chr15_-_98626002 0.50 ENSMUST00000003445.8
FK506 binding protein 11
chr1_-_93373364 0.49 ENSMUST00000190321.7
ENSMUST00000042498.14
high density lipoprotein (HDL) binding protein
chr3_+_89366425 0.49 ENSMUST00000029564.12
phosphomevalonate kinase
chr7_-_45116316 0.48 ENSMUST00000033093.10
BCL2-associated X protein
chr2_-_105229653 0.48 ENSMUST00000006128.7
reticulocalbin 1
chr16_-_94171853 0.46 ENSMUST00000113914.8
ENSMUST00000113905.8
phosphatidylinositol glycan anchor biosynthesis, class P
chr5_+_45677571 0.45 ENSMUST00000156481.8
ENSMUST00000119579.3
ENSMUST00000118833.3
mediator complex subunit 28
chr9_+_44290832 0.45 ENSMUST00000161318.8
ENSMUST00000217019.2
ENSMUST00000160902.8
hypoxia up-regulated 1
chr6_+_88442391 0.44 ENSMUST00000032165.16
RuvB-like protein 1
chr10_+_88566918 0.44 ENSMUST00000116234.9
ADP-ribosylation factor-like 1
chr15_+_44291470 0.43 ENSMUST00000226827.2
ENSMUST00000060652.5
ENY2 transcription and export complex 2 subunit
chr5_-_137531463 0.42 ENSMUST00000170293.8
guanine nucleotide binding protein (G protein), beta 2
chr13_-_111626562 0.42 ENSMUST00000091236.11
ENSMUST00000047627.14
GC-rich promoter binding protein 1
chr7_+_65759198 0.41 ENSMUST00000036372.8
chondroitin sulfate synthase 1
chr1_-_131025562 0.41 ENSMUST00000016672.11
MAP kinase-activated protein kinase 2
chr13_-_119545479 0.41 ENSMUST00000223268.2
nicotinamide nucleotide transhydrogenase
chr11_-_69811717 0.40 ENSMUST00000152589.2
ENSMUST00000108612.8
ENSMUST00000108611.8
eukaryotic translation initiation factor 5A
chr7_-_30814652 0.40 ENSMUST00000168884.8
ENSMUST00000108102.9
hepsin
chr4_+_102843540 0.39 ENSMUST00000030248.12
ENSMUST00000125417.9
ENSMUST00000169211.3
dynein light chain Tctex-type 5
chr4_+_47474652 0.39 ENSMUST00000065678.6
Sec61 beta subunit
chr6_+_134617903 0.39 ENSMUST00000062755.10
BLOC-1 related complex subunit 5
chr12_-_13299197 0.39 ENSMUST00000071103.10
DEAD box helicase 1
chr11_-_93776580 0.38 ENSMUST00000066888.10
UTP18 small subunit processome component
chr5_-_52628825 0.38 ENSMUST00000198008.5
ENSMUST00000059428.7
coiled-coil domain containing 149
chr17_+_35117905 0.38 ENSMUST00000097342.10
ENSMUST00000013931.12
euchromatic histone lysine N-methyltransferase 2
chr5_-_137531413 0.38 ENSMUST00000168746.8
guanine nucleotide binding protein (G protein), beta 2
chr5_+_30824121 0.38 ENSMUST00000144742.6
ENSMUST00000149759.2
ENSMUST00000199320.5
centromere protein A
chr12_-_13299136 0.38 ENSMUST00000221623.2
DEAD box helicase 1
chr19_+_23118545 0.37 ENSMUST00000036884.3
Kruppel-like factor 9
chrX_+_133618693 0.37 ENSMUST00000113201.8
ENSMUST00000051256.10
ENSMUST00000113199.8
ENSMUST00000035748.14
ENSMUST00000113198.8
ENSMUST00000113197.2
armadillo repeat containing, X-linked 1
chr11_-_69872050 0.37 ENSMUST00000108594.8
elongator acetyltransferase complex subunit 5
chr9_+_44290787 0.37 ENSMUST00000066601.13
hypoxia up-regulated 1
chr13_-_119545520 0.36 ENSMUST00000069902.13
ENSMUST00000099149.10
ENSMUST00000109204.8
nicotinamide nucleotide transhydrogenase
chr16_+_17577464 0.36 ENSMUST00000129199.8
kelch-like 22
chr1_+_157334298 0.36 ENSMUST00000086130.9
SEC16 homolog B (S. cerevisiae)
chr1_+_157334347 0.36 ENSMUST00000027881.15
SEC16 homolog B (S. cerevisiae)
chr16_+_17577493 0.36 ENSMUST00000165790.9
kelch-like 22
chr10_+_128158413 0.36 ENSMUST00000219836.2
canopy FGF signaling regulator 2
chr12_+_84363603 0.35 ENSMUST00000045931.12
zinc finger protein 410
chr17_-_29566774 0.35 ENSMUST00000095427.12
ENSMUST00000118366.9
mitochondrial carrier 1
chr11_-_69811890 0.35 ENSMUST00000108609.8
ENSMUST00000108608.8
ENSMUST00000164359.8
eukaryotic translation initiation factor 5A
chr15_-_79571977 0.35 ENSMUST00000023061.7
Josephin domain containing 1
chr8_+_26210064 0.35 ENSMUST00000068916.16
ENSMUST00000139836.8
phospholipid phosphatase 5
chr6_-_115735935 0.35 ENSMUST00000072933.13
transmembrane protein 40
chr13_+_93440265 0.35 ENSMUST00000109494.8
homer scaffolding protein 1
chrX_-_135642025 0.34 ENSMUST00000155207.8
ENSMUST00000080411.13
ENSMUST00000169418.8
mortality factor 4 like 2
chr4_+_47474715 0.34 ENSMUST00000137461.8
ENSMUST00000125622.2
Sec61 beta subunit
chr17_+_29709723 0.34 ENSMUST00000024811.9
proviral integration site 1
chr6_-_131270136 0.34 ENSMUST00000032307.12
mago homolog B, exon junction complex core component
chrX_+_49930311 0.34 ENSMUST00000114887.9
serine/threonine kinase 26
chr3_-_143910926 0.33 ENSMUST00000120539.8
ENSMUST00000196264.5
LIM domain only 4
chr11_+_87938626 0.33 ENSMUST00000107920.10
serine and arginine-rich splicing factor 1
chr9_+_120321557 0.33 ENSMUST00000007139.6
eukaryotic translation initiation factor 1B
chr8_-_86281946 0.33 ENSMUST00000034138.7
DnaJ heat shock protein family (Hsp40) member A2
chr4_+_46489248 0.33 ENSMUST00000030018.5
N-acetylneuraminic acid synthase (sialic acid synthase)
chr4_-_150994083 0.33 ENSMUST00000105674.8
ENSMUST00000105673.8
Parkinson disease (autosomal recessive, early onset) 7
chr13_+_93440572 0.33 ENSMUST00000109493.9
homer scaffolding protein 1
chr10_-_84369831 0.33 ENSMUST00000167671.2
ENSMUST00000053871.5
cytoskeleton-associated protein 4
chr7_-_84339045 0.32 ENSMUST00000209165.2
zinc finger, AN1-type domain 6
chr15_-_44291699 0.32 ENSMUST00000038719.8
NudC domain containing 1
chr2_+_75489596 0.32 ENSMUST00000111964.8
ENSMUST00000111962.8
ENSMUST00000111961.8
ENSMUST00000164947.9
ENSMUST00000090792.11
heterogeneous nuclear ribonucleoprotein A3
chr3_+_123061094 0.32 ENSMUST00000047923.12
ENSMUST00000200333.2
Sec24 related gene family, member D (S. cerevisiae)
chr15_+_78915071 0.32 ENSMUST00000006544.9
ENSMUST00000171999.9
glycine C-acetyltransferase (2-amino-3-ketobutyrate-coenzyme A ligase)
glycine C-acetyltransferase (2-amino-3-ketobutyrate-coenzyme A ligase)
chr3_+_87754057 0.32 ENSMUST00000107581.9
SH2 domain containing 2A
chr19_-_41252370 0.31 ENSMUST00000237871.2
ENSMUST00000025989.10
transmembrane 9 superfamily member 3
chr11_-_72106418 0.31 ENSMUST00000021157.9
mediator complex subunit 31
chr2_+_164587948 0.31 ENSMUST00000109327.4
deoxynucleotidyltransferase, terminal, interacting protein 1
chr11_+_96209093 0.31 ENSMUST00000049241.9
homeobox B4
chr4_+_33031342 0.31 ENSMUST00000124992.8
ubiquitin-conjugating enzyme E2J 1
chr3_+_131270529 0.30 ENSMUST00000029666.14
3'-phosphoadenosine 5'-phosphosulfate synthase 1
chr11_-_6217718 0.30 ENSMUST00000004507.11
ENSMUST00000151446.2
DEAD box helicase 56
chr16_-_94171533 0.30 ENSMUST00000113910.8
phosphatidylinositol glycan anchor biosynthesis, class P
chr17_+_35117438 0.30 ENSMUST00000114033.9
ENSMUST00000078061.13
euchromatic histone lysine N-methyltransferase 2
chr9_+_108216433 0.30 ENSMUST00000191997.2
glutathione peroxidase 1
chr6_+_116314975 0.30 ENSMUST00000079012.13
ENSMUST00000101032.10
ENSMUST00000123405.8
ENSMUST00000204657.3
ENSMUST00000203116.2
ENSMUST00000203193.3
ENSMUST00000126376.8
membrane associated ring-CH-type finger 8
chr11_+_94520567 0.30 ENSMUST00000021239.7
leucine rich repeat containing 59
chr15_-_98729333 0.29 ENSMUST00000168846.3
protein kinase, AMP-activated, gamma 1 non-catalytic subunit
chr9_-_62029877 0.29 ENSMUST00000185675.7
glucuronyl C5-epimerase
chr6_-_119825081 0.29 ENSMUST00000183703.8
ENSMUST00000183911.8
ELKS/RAB6-interacting/CAST family member 1
chr5_-_124490296 0.29 ENSMUST00000111472.6
CDK2 (cyclin-dependent kinase 2)-associated protein 1
chr8_+_26210484 0.29 ENSMUST00000210629.2
phospholipid phosphatase 5
chr5_-_65650269 0.29 ENSMUST00000121661.8
small integral membrane protein 14
chr11_-_103588605 0.29 ENSMUST00000021329.14
golgi SNAP receptor complex member 2
chr19_-_53026965 0.28 ENSMUST00000183274.8
ENSMUST00000182097.2
X-prolyl aminopeptidase (aminopeptidase P) 1, soluble
chr8_-_106692668 0.28 ENSMUST00000116429.9
ENSMUST00000034370.17
solute carrier family 12, member 4
chrX_-_135641869 0.28 ENSMUST00000166930.8
ENSMUST00000113095.8
mortality factor 4 like 2
chr19_+_8849000 0.28 ENSMUST00000096255.7
UBX domain protein 1
chr13_+_33187205 0.28 ENSMUST00000063191.14
serine (or cysteine) peptidase inhibitor, clade B, member 9
chr9_+_107468146 0.28 ENSMUST00000195746.2
interferon-related developmental regulator 2
chr9_+_57428490 0.27 ENSMUST00000000090.8
cytochrome c oxidase subunit 5A
chr12_-_84455764 0.27 ENSMUST00000120942.8
ENSMUST00000110272.9
ectonucleoside triphosphate diphosphohydrolase 5
chr17_-_34250616 0.27 ENSMUST00000169397.9
solute carrier family 39 (zinc transporter), member 7
chr12_+_51424343 0.27 ENSMUST00000219434.2
ENSMUST00000021335.7
Sec1 family domain containing 1
chr8_-_13155431 0.27 ENSMUST00000164416.8
PCI domain containing 2
chr12_-_59058780 0.27 ENSMUST00000021375.12
SEC23 homolog A, COPII coat complex component
chr1_-_161078723 0.27 ENSMUST00000051925.5
ENSMUST00000071718.12
peroxiredoxin 6
chrX_-_133501874 0.26 ENSMUST00000033621.8
galactosidase, alpha
chr17_-_65920481 0.26 ENSMUST00000024897.10
vesicle-associated membrane protein, associated protein A
chr1_+_171173252 0.26 ENSMUST00000006579.5
prefoldin 2
chr2_+_121279842 0.26 ENSMUST00000110615.8
ENSMUST00000099475.12
small EDRK-rich factor 2
chr1_+_91468266 0.26 ENSMUST00000086843.11
ankyrin repeat and SOCS box-containing 1
chr11_-_102771751 0.26 ENSMUST00000021306.14
elongation factor Tu GTP binding domain containing 2
chr13_-_100969823 0.26 ENSMUST00000225922.2
solute carrier family 30 (zinc transporter), member 5
chr19_+_8944369 0.25 ENSMUST00000052248.8
eukaryotic translation elongation factor 1 gamma
chr4_-_129271909 0.25 ENSMUST00000030610.3
zinc finger and BTB domain containing 8a
chr9_+_59198829 0.25 ENSMUST00000217570.2
ENSMUST00000026266.9
ADP-dependent glucokinase
chr19_-_46950355 0.25 ENSMUST00000236501.2
5'-nucleotidase, cytosolic II
chr17_-_67661382 0.25 ENSMUST00000223982.2
ENSMUST00000224091.2
protein tyrosine phosphatase, receptor type, M
chr3_+_89366632 0.25 ENSMUST00000107410.8
phosphomevalonate kinase
chr2_+_18677195 0.25 ENSMUST00000171845.8
ENSMUST00000061158.5
COMM domain containing 3
chr9_-_89996712 0.25 ENSMUST00000191353.2
ENSMUST00000085248.12
mortality factor 4 like 1
chr7_+_45522551 0.25 ENSMUST00000211234.2
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 1
chr10_-_18619658 0.24 ENSMUST00000215836.2
ARFGEF family member 3
chr4_+_88012836 0.24 ENSMUST00000097992.10
focadhesin
chr12_+_84455813 0.24 ENSMUST00000081828.13
basal body orientation factor 1
chr12_+_72488625 0.24 ENSMUST00000161284.3
ENSMUST00000162159.8
leucine rich repeat containing 9
chr17_+_25352353 0.24 ENSMUST00000162862.3
ENSMUST00000040729.9
chloride channel, voltage-sensitive 7
chr3_+_40904253 0.24 ENSMUST00000048490.13
La ribonucleoprotein domain family, member 1B
chr6_+_17694003 0.24 ENSMUST00000052113.12
ENSMUST00000081635.13
suppression of tumorigenicity 7
chr3_-_37778470 0.24 ENSMUST00000108105.2
ENSMUST00000079755.5
ENSMUST00000099128.2
predicted gene 5148
chr4_+_3938881 0.24 ENSMUST00000108386.8
ENSMUST00000121110.8
ENSMUST00000149544.8
coiled-coil-helix-coiled-coil-helix domain containing 7
chrX_+_133501928 0.24 ENSMUST00000074950.11
ENSMUST00000113203.2
ENSMUST00000113202.8
ENSMUST00000050331.13
ENSMUST00000059297.6
heterogeneous nuclear ribonucleoprotein H2
chr5_+_143389573 0.23 ENSMUST00000110731.4
KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2
chr18_+_34994253 0.23 ENSMUST00000165033.2
early growth response 1
chr9_+_59446823 0.23 ENSMUST00000026262.8
hexosaminidase A
chr11_-_102771806 0.23 ENSMUST00000107060.8
elongation factor Tu GTP binding domain containing 2
chr8_+_13807652 0.23 ENSMUST00000130173.9
ENSMUST00000043962.9
ENSMUST00000134645.8
CDC16 cell division cycle 16
chr7_-_113875261 0.23 ENSMUST00000135570.8
proteasome subunit alpha 1
chr6_+_134012602 0.23 ENSMUST00000081028.13
ENSMUST00000111963.8
ets variant 6
chr19_+_8718837 0.23 ENSMUST00000177373.8
ENSMUST00000010254.16
syntaxin 5A
chr11_-_69812053 0.23 ENSMUST00000108613.10
ENSMUST00000043419.10
ENSMUST00000070996.11
eukaryotic translation initiation factor 5A
chr14_+_70314727 0.23 ENSMUST00000225200.2
early growth response 3
chr7_-_44778050 0.23 ENSMUST00000209711.2
ENSMUST00000211037.2
ENSMUST00000209927.2
ENSMUST00000209815.2
ENSMUST00000210918.2
ENSMUST00000150350.9
ribosomal protein L13A
chr5_-_123127346 0.22 ENSMUST00000118027.8
lysine (K)-specific demethylase 2B
chr17_-_25459086 0.22 ENSMUST00000038973.7
ENSMUST00000115154.11
N-acetylglucosamine-1-phosphotransferase, gamma subunit
chr11_+_62442502 0.22 ENSMUST00000136938.2
ubiquitin B
chr19_+_8719033 0.22 ENSMUST00000176314.8
ENSMUST00000073430.14
ENSMUST00000175901.8
syntaxin 5A
chr13_-_100969878 0.22 ENSMUST00000067246.6
solute carrier family 30 (zinc transporter), member 5
chr4_+_8535604 0.22 ENSMUST00000060232.8
RAB2A, member RAS oncogene family
chr11_+_87017878 0.22 ENSMUST00000041282.13
tripartite motif-containing 37
chr19_+_8848924 0.22 ENSMUST00000238036.2
UBX domain protein 1
chrX_-_133501677 0.22 ENSMUST00000239113.2
galactosidase, alpha
chr12_+_3941728 0.22 ENSMUST00000172689.8
ENSMUST00000111186.8
DNA methyltransferase 3A
chrX_-_73416824 0.21 ENSMUST00000178691.2
ENSMUST00000114146.8
ubiquitin-like 4A
solute carrier family 10 (sodium/bile acid cotransporter family), member 3
chr19_+_8848876 0.21 ENSMUST00000166407.9
UBX domain protein 1
chr8_+_86219191 0.21 ENSMUST00000034136.12
glutamic pyruvate transaminase (alanine aminotransferase) 2
chr8_+_106895488 0.21 ENSMUST00000034378.5
ENSMUST00000212421.2
solute carrier family 7 (cationic amino acid transporter, y+ system), member 6
chr17_+_57586094 0.21 ENSMUST00000169220.9
ENSMUST00000005889.16
ENSMUST00000112870.5
vav 1 oncogene
chr6_+_17694153 0.21 ENSMUST00000115418.8
suppression of tumorigenicity 7
chr8_-_34614187 0.21 ENSMUST00000033910.9
leptin receptor overlapping transcript-like 1
chr8_+_107783502 0.20 ENSMUST00000034392.13
ENSMUST00000170962.3
NIP7, nucleolar pre-rRNA processing protein
chr3_+_51323383 0.20 ENSMUST00000029303.13
N(alpha)-acetyltransferase 15, NatA auxiliary subunit
chr1_-_170002444 0.20 ENSMUST00000111351.10
ENSMUST00000027981.8
UDP-N-acetylglucosamine pyrophosphorylase 1
chr4_-_135714465 0.20 ENSMUST00000105851.9
PITH (C-terminal proteasome-interacting domain of thioredoxin-like) domain containing 1
chr9_-_107167046 0.20 ENSMUST00000035194.8
mitogen-activated protein kinase-activated protein kinase 3
chr4_+_130001349 0.20 ENSMUST00000030563.6
penta-EF hand domain containing 1
chr16_-_19801781 0.20 ENSMUST00000058839.10
kelch-like 6
chr7_-_110682204 0.20 ENSMUST00000161051.8
ENSMUST00000160132.8
ENSMUST00000162415.9
eukaryotic translation initiation factor 4, gamma 2
chr11_-_69811347 0.20 ENSMUST00000108610.8
eukaryotic translation initiation factor 5A
chr11_-_103588487 0.20 ENSMUST00000107013.3
golgi SNAP receptor complex member 2
chrX_-_93166992 0.20 ENSMUST00000088102.12
ENSMUST00000113927.8
zinc finger protein X-linked
chr3_+_40699763 0.19 ENSMUST00000203353.3
heat shock protein 4 like
chr13_-_38178059 0.19 ENSMUST00000225319.2
ENSMUST00000225246.2
ENSMUST00000021864.8
signal sequence receptor, alpha
chr1_-_170002526 0.19 ENSMUST00000111350.10
UDP-N-acetylglucosamine pyrophosphorylase 1
chr19_+_6135013 0.19 ENSMUST00000025704.3
cell division cycle associated 5
chr15_-_97664931 0.19 ENSMUST00000177352.8
Rap guanine nucleotide exchange factor (GEF) 3
chr8_-_68270870 0.19 ENSMUST00000059374.5
pleckstrin and Sec7 domain containing 3
chr2_+_129854256 0.19 ENSMUST00000110299.3
transglutaminase 3, E polypeptide
chr1_+_155916655 0.19 ENSMUST00000065648.15
ENSMUST00000097526.3
torsin A interacting protein 2
chr9_-_36678868 0.19 ENSMUST00000217599.2
ENSMUST00000120381.9
STT3, subunit of the oligosaccharyltransferase complex, homolog A (S. cerevisiae)
chr1_+_135060994 0.19 ENSMUST00000167080.3
protein tyrosine phosphatase, non-receptor type 7
chr9_+_44238089 0.18 ENSMUST00000054708.5
dolichyl-phosphate (UDP-N-acetylglucosamine) acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase)
chr15_+_34082805 0.18 ENSMUST00000022865.17
metadherin
chr11_+_87938519 0.18 ENSMUST00000079866.11
serine and arginine-rich splicing factor 1
chr5_-_145138639 0.18 ENSMUST00000162220.2
ENSMUST00000031632.9
ENSMUST00000198959.2
zinc finger with KRAB and SCAN domains 14
chr11_+_87018079 0.18 ENSMUST00000139532.2
tripartite motif-containing 37
chr10_-_43777712 0.18 ENSMUST00000020012.7
glutaminyl-tRNA synthase (glutamine-hydrolyzing)-like 1
chr10_+_79613083 0.18 ENSMUST00000020575.5
follistatin-like 3
chr9_-_50256268 0.18 ENSMUST00000076364.6
ribosomal protein L10, pseudogene 3
chr6_+_17693941 0.18 ENSMUST00000115420.8
ENSMUST00000115419.8
suppression of tumorigenicity 7
chr11_-_20781009 0.17 ENSMUST00000047028.9
lectin, galactoside binding-like
chr1_-_89858901 0.17 ENSMUST00000036954.9
gastrulation brain homeobox 2
chr13_-_36918424 0.17 ENSMUST00000037623.15
neuritin 1

Network of associatons between targets according to the STRING database.

First level regulatory network of Atf6

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:1990117 release of matrix enzymes from mitochondria(GO:0032976) B cell receptor apoptotic signaling pathway(GO:1990117)
0.4 2.2 GO:0006452 translational frameshifting(GO:0006452) positive regulation of translational termination(GO:0045905)
0.3 0.8 GO:0006740 NADPH regeneration(GO:0006740)
0.2 0.7 GO:0031204 posttranslational protein targeting to membrane, translocation(GO:0031204)
0.2 0.7 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.2 0.5 GO:0042726 flavin-containing compound metabolic process(GO:0042726)
0.2 1.0 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.2 1.2 GO:1903093 regulation of protein K48-linked deubiquitination(GO:1903093) negative regulation of protein K48-linked deubiquitination(GO:1903094) negative regulation of ubiquitin-specific protease activity(GO:2000157)
0.1 0.7 GO:0072531 pyrimidine-containing compound transmembrane transport(GO:0072531)
0.1 0.7 GO:0036166 phenotypic switching(GO:0036166) cellular response to cocaine(GO:0071314)
0.1 0.4 GO:0034769 basement membrane disassembly(GO:0034769)
0.1 0.4 GO:0010269 response to symbiont(GO:0009608) response to symbiotic bacterium(GO:0009609) response to selenium ion(GO:0010269)
0.1 0.9 GO:0048208 vesicle targeting, rough ER to cis-Golgi(GO:0048207) COPII vesicle coating(GO:0048208)
0.1 0.4 GO:0021993 initiation of neural tube closure(GO:0021993)
0.1 0.3 GO:0030210 heparin biosynthetic process(GO:0030210)
0.1 0.2 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.1 0.2 GO:0042222 interleukin-1 biosynthetic process(GO:0042222)
0.1 0.5 GO:0010756 positive regulation of plasminogen activation(GO:0010756)
0.1 0.3 GO:0046167 glycerol-3-phosphate biosynthetic process(GO:0046167)
0.1 0.7 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.1 0.8 GO:1903298 regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903297) negative regulation of hypoxia-induced intrinsic apoptotic signaling pathway(GO:1903298)
0.1 0.2 GO:0016256 N-glycan processing to lysosome(GO:0016256)
0.1 1.0 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.1 0.5 GO:0045716 positive regulation of low-density lipoprotein particle receptor biosynthetic process(GO:0045716)
0.1 0.8 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.1 0.4 GO:0006048 UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.1 0.4 GO:0007296 vitellogenesis(GO:0007296)
0.1 0.4 GO:0006621 protein retention in ER lumen(GO:0006621)
0.1 0.2 GO:0043686 co-translational protein modification(GO:0043686)
0.1 0.7 GO:0035873 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
0.1 0.5 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.1 0.4 GO:0090086 negative regulation of protein deubiquitination(GO:0090086)
0.1 0.2 GO:0070681 glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.1 0.4 GO:0036353 histone H2A-K119 monoubiquitination(GO:0036353)
0.1 0.1 GO:1902065 response to L-glutamate(GO:1902065)
0.1 0.2 GO:0021555 midbrain-hindbrain boundary morphogenesis(GO:0021555)
0.1 0.3 GO:0000973 posttranscriptional tethering of RNA polymerase II gene DNA at nuclear periphery(GO:0000973) nuclear retention of pre-mRNA at the site of transcription(GO:0071033)
0.1 0.4 GO:0050847 progesterone receptor signaling pathway(GO:0050847)
0.1 0.2 GO:0097212 cleavage furrow ingression(GO:0036090) lysosomal membrane organization(GO:0097212)
0.1 0.2 GO:0042851 L-alanine metabolic process(GO:0042851)
0.0 0.2 GO:1904453 regulation of hydrogen:potassium-exchanging ATPase activity(GO:1904451) positive regulation of hydrogen:potassium-exchanging ATPase activity(GO:1904453)
0.0 0.5 GO:1904153 negative regulation of protein exit from endoplasmic reticulum(GO:0070862) negative regulation of retrograde protein transport, ER to cytosol(GO:1904153)
0.0 0.1 GO:1902219 negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902219)
0.0 0.3 GO:0019348 dolichol metabolic process(GO:0019348)
0.0 0.5 GO:0044351 macropinocytosis(GO:0044351)
0.0 0.1 GO:0019264 glycine biosynthetic process from serine(GO:0019264)
0.0 0.4 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.0 0.1 GO:0060574 intestinal epithelial cell maturation(GO:0060574)
0.0 0.3 GO:0010815 bradykinin catabolic process(GO:0010815)
0.0 0.1 GO:0016093 polyprenol metabolic process(GO:0016093)
0.0 0.5 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.0 0.3 GO:0048539 bone marrow development(GO:0048539)
0.0 0.2 GO:0071921 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.0 0.2 GO:0021888 hypothalamus gonadotrophin-releasing hormone neuron differentiation(GO:0021886) hypothalamus gonadotrophin-releasing hormone neuron development(GO:0021888)
0.0 0.1 GO:2001245 regulation of phosphatidylcholine biosynthetic process(GO:2001245)
0.0 0.7 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.0 0.1 GO:0002270 plasmacytoid dendritic cell activation(GO:0002270)
0.0 0.3 GO:0042270 protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.0 0.5 GO:0006824 cobalt ion transport(GO:0006824)
0.0 0.4 GO:0070561 vitamin D receptor signaling pathway(GO:0070561) regulation of hematopoietic stem cell proliferation(GO:1902033)
0.0 0.3 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
0.0 0.9 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.1 GO:1901526 positive regulation of macromitophagy(GO:1901526) positive regulation of mitophagy in response to mitochondrial depolarization(GO:1904925)
0.0 0.1 GO:0000415 negative regulation of histone H3-K36 methylation(GO:0000415)
0.0 0.4 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
0.0 0.1 GO:0021660 rhombomere formation(GO:0021594) rhombomere 3 formation(GO:0021660) rhombomere 5 morphogenesis(GO:0021664) rhombomere 5 formation(GO:0021666)
0.0 0.2 GO:0032511 late endosome to vacuole transport via multivesicular body sorting pathway(GO:0032511)
0.0 0.4 GO:1902474 positive regulation of protein localization to synapse(GO:1902474)
0.0 0.2 GO:0006689 ganglioside catabolic process(GO:0006689) glycosphingolipid catabolic process(GO:0046479)
0.0 0.1 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089)
0.0 0.5 GO:0032776 DNA methylation on cytosine(GO:0032776)
0.0 0.3 GO:1902902 negative regulation of autophagosome assembly(GO:1902902)
0.0 0.2 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0 0.4 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.0 0.2 GO:0090168 Golgi reassembly(GO:0090168)
0.0 0.1 GO:2000819 regulation of nucleotide-excision repair(GO:2000819)
0.0 0.1 GO:0030043 actin filament fragmentation(GO:0030043)
0.0 0.2 GO:0071816 tail-anchored membrane protein insertion into ER membrane(GO:0071816)
0.0 0.1 GO:0017187 peptidyl-glutamic acid carboxylation(GO:0017187)
0.0 0.2 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.0 0.4 GO:0071459 protein localization to chromosome, centromeric region(GO:0071459)
0.0 0.1 GO:0051385 response to mineralocorticoid(GO:0051385)
0.0 0.7 GO:0032012 ARF protein signal transduction(GO:0032011) regulation of ARF protein signal transduction(GO:0032012)
0.0 0.4 GO:0016973 poly(A)+ mRNA export from nucleus(GO:0016973)
0.0 0.3 GO:0006123 mitochondrial electron transport, cytochrome c to oxygen(GO:0006123)
0.0 0.1 GO:0007253 cytoplasmic sequestering of NF-kappaB(GO:0007253)
0.0 0.4 GO:0009404 toxin metabolic process(GO:0009404)
0.0 0.7 GO:0071173 mitotic spindle assembly checkpoint(GO:0007094) spindle assembly checkpoint(GO:0071173)
0.0 0.4 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.2 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.0 0.1 GO:1903760 regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization(GO:1903760)
0.0 0.1 GO:0035720 intraciliary anterograde transport(GO:0035720)
0.0 0.1 GO:0060578 subthalamic nucleus development(GO:0021763) superior vena cava morphogenesis(GO:0060578)
0.0 0.6 GO:0009311 oligosaccharide metabolic process(GO:0009311)
0.0 0.2 GO:0051388 positive regulation of neurotrophin TRK receptor signaling pathway(GO:0051388)
0.0 0.3 GO:2000400 positive regulation of T cell differentiation in thymus(GO:0033089) positive regulation of thymocyte aggregation(GO:2000400)
0.0 0.7 GO:0006506 GPI anchor biosynthetic process(GO:0006506)
0.0 0.1 GO:0009744 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.0 0.2 GO:0034982 mitochondrial protein processing(GO:0034982)
0.0 0.7 GO:0018279 protein N-linked glycosylation via asparagine(GO:0018279)
0.0 0.2 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.0 0.1 GO:0009826 unidimensional cell growth(GO:0009826)
0.0 0.4 GO:0060746 parental behavior(GO:0060746)
0.0 0.1 GO:0071638 negative regulation of monocyte chemotactic protein-1 production(GO:0071638)
0.0 0.6 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.0 0.1 GO:0007501 mesodermal cell fate specification(GO:0007501)
0.0 0.1 GO:0051045 negative regulation of membrane protein ectodomain proteolysis(GO:0051045)
0.0 0.2 GO:0032926 negative regulation of activin receptor signaling pathway(GO:0032926)
0.0 0.2 GO:0034498 early endosome to Golgi transport(GO:0034498)
0.0 0.0 GO:0033128 negative regulation of histone phosphorylation(GO:0033128) cell proliferation involved in heart valve development(GO:2000793)
0.0 0.2 GO:0009191 ribonucleoside diphosphate catabolic process(GO:0009191)
0.0 0.1 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.0 0.5 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.0 0.1 GO:2000017 positive regulation of determination of dorsal identity(GO:2000017)
0.0 0.2 GO:0006613 cotranslational protein targeting to membrane(GO:0006613)
0.0 0.3 GO:0046475 glycerophospholipid catabolic process(GO:0046475)
0.0 0.1 GO:0033227 dsRNA transport(GO:0033227)
0.0 0.3 GO:0030539 male genitalia development(GO:0030539)
0.0 0.3 GO:0042659 regulation of cell fate specification(GO:0042659)
0.0 0.4 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.1 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480) positive regulation of tau-protein kinase activity(GO:1902949)
0.0 0.1 GO:0040016 embryonic cleavage(GO:0040016)
0.0 0.0 GO:0018312 peptidyl-serine ADP-ribosylation(GO:0018312)
0.0 0.3 GO:0042026 protein refolding(GO:0042026)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0097144 BAX complex(GO:0097144)
0.2 0.8 GO:0071920 cleavage body(GO:0071920)
0.2 0.5 GO:1990730 VCP-NSFL1C complex(GO:1990730)
0.2 2.1 GO:0005642 annulate lamellae(GO:0005642)
0.1 1.8 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.1 0.7 GO:0031205 endoplasmic reticulum Sec complex(GO:0031205)
0.1 0.4 GO:0000939 condensed chromosome inner kinetochore(GO:0000939)
0.1 0.7 GO:0005827 polar microtubule(GO:0005827)
0.1 0.2 GO:0018444 translation release factor complex(GO:0018444)
0.1 0.2 GO:0070985 TFIIK complex(GO:0070985)
0.1 0.8 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.1 0.2 GO:0030956 glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.1 0.4 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.1 0.4 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.1 0.4 GO:0097413 Lewy body(GO:0097413)
0.1 0.9 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 0.4 GO:0097255 R2TP complex(GO:0097255)
0.0 0.2 GO:0097574 lateral part of cell(GO:0097574) basolateral part of cell(GO:1990794) rod bipolar cell terminal bouton(GO:1990795)
0.0 0.4 GO:0098574 cytoplasmic side of lysosomal membrane(GO:0098574)
0.0 0.9 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.2 GO:0005745 m-AAA complex(GO:0005745)
0.0 0.3 GO:0070847 core mediator complex(GO:0070847)
0.0 0.2 GO:0097452 GAIT complex(GO:0097452)
0.0 0.3 GO:0000808 origin recognition complex(GO:0000808) nuclear origin of replication recognition complex(GO:0005664)
0.0 1.2 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.4 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.9 GO:1902562 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 1.0 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.4 GO:0000124 SAGA complex(GO:0000124)
0.0 0.3 GO:0016281 eukaryotic translation initiation factor 4F complex(GO:0016281)
0.0 0.2 GO:0072379 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0 0.3 GO:0016272 prefoldin complex(GO:0016272)
0.0 0.2 GO:0005766 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0 0.6 GO:0035098 ESC/E(Z) complex(GO:0035098)
0.0 0.1 GO:0014701 junctional sarcoplasmic reticulum membrane(GO:0014701)
0.0 0.2 GO:0008278 cohesin complex(GO:0008278)
0.0 0.2 GO:0031415 NatA complex(GO:0031415)
0.0 0.3 GO:0017119 Golgi transport complex(GO:0017119)
0.0 1.1 GO:0031201 SNARE complex(GO:0031201)
0.0 0.5 GO:0046540 U4/U6 x U5 tri-snRNP complex(GO:0046540)
0.0 0.3 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 1.0 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.3 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.1 GO:0072487 MSL complex(GO:0072487)
0.0 0.3 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 0.1 GO:0031298 replication fork protection complex(GO:0031298)
0.0 0.2 GO:0032580 Golgi cisterna membrane(GO:0032580)
0.0 0.2 GO:0046581 intercellular canaliculus(GO:0046581)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0071796 K6-linked polyubiquitin binding(GO:0071796)
0.2 0.5 GO:0052692 raffinose alpha-galactosidase activity(GO:0052692)
0.2 0.8 GO:0033677 DNA/RNA helicase activity(GO:0033677)
0.1 1.4 GO:0051434 BH3 domain binding(GO:0051434)
0.1 0.4 GO:0050510 N-acetylgalactosaminyl-proteoglycan 3-beta-glucuronosyltransferase activity(GO:0050510)
0.1 0.5 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.1 0.4 GO:0003977 UDP-N-acetylglucosamine diphosphorylase activity(GO:0003977)
0.1 2.2 GO:0017070 U6 snRNA binding(GO:0017070)
0.1 0.7 GO:0048408 epidermal growth factor binding(GO:0048408)
0.1 0.5 GO:0036470 tyrosine 3-monooxygenase activator activity(GO:0036470) L-dopa decarboxylase activator activity(GO:0036478)
0.1 0.4 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.1 0.7 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.1 0.3 GO:0033149 FFAT motif binding(GO:0033149)
0.1 0.4 GO:0046923 ER retention sequence binding(GO:0046923)
0.1 0.4 GO:0004382 guanosine-diphosphatase activity(GO:0004382)
0.1 0.7 GO:0046974 histone methyltransferase activity (H3-K9 specific)(GO:0046974)
0.1 0.7 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.1 0.8 GO:0004576 oligosaccharyl transferase activity(GO:0004576) dolichyl-diphosphooligosaccharide-protein glycotransferase activity(GO:0004579)
0.1 0.3 GO:0004370 glycerol kinase activity(GO:0004370)
0.1 0.4 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.1 1.0 GO:0016671 oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor(GO:0016671)
0.1 0.2 GO:0050567 glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
0.1 0.4 GO:0051032 nucleic acid transmembrane transporter activity(GO:0051032) RNA transmembrane transporter activity(GO:0051033)
0.1 0.7 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.1 0.7 GO:0031802 type 5 metabotropic glutamate receptor binding(GO:0031802)
0.1 1.0 GO:0015926 glucosidase activity(GO:0015926)
0.0 0.1 GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.0 0.2 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.4 GO:0008508 bile acid:sodium symporter activity(GO:0008508)
0.0 0.1 GO:0004372 glycine hydroxymethyltransferase activity(GO:0004372)
0.0 0.2 GO:0004021 L-alanine:2-oxoglutarate aminotransferase activity(GO:0004021) alanine-oxo-acid transaminase activity(GO:0047635)
0.0 0.1 GO:0000402 open form four-way junction DNA binding(GO:0000401) crossed form four-way junction DNA binding(GO:0000402)
0.0 0.2 GO:0044729 double-stranded methylated DNA binding(GO:0010385) hemi-methylated DNA-binding(GO:0044729)
0.0 0.1 GO:0005128 erythropoietin receptor binding(GO:0005128)
0.0 0.1 GO:0047057 oxidoreductase activity, acting on the CH-OH group of donors, disulfide as acceptor(GO:0016900) vitamin-K-epoxide reductase (warfarin-sensitive) activity(GO:0047057)
0.0 0.1 GO:0004582 dolichyl-phosphate beta-D-mannosyltransferase activity(GO:0004582)
0.0 0.4 GO:0043024 ribosomal small subunit binding(GO:0043024)
0.0 0.2 GO:0003747 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.0 0.1 GO:0016426 tRNA (adenine) methyltransferase activity(GO:0016426)
0.0 0.5 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 0.1 GO:0097100 supercoiled DNA binding(GO:0097100)
0.0 0.1 GO:0046964 3'-phosphoadenosine 5'-phosphosulfate transmembrane transporter activity(GO:0046964)
0.0 0.7 GO:0015215 nucleotide transmembrane transporter activity(GO:0015215)
0.0 0.1 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.0 0.6 GO:0008195 phosphatidate phosphatase activity(GO:0008195)
0.0 0.4 GO:0070008 serine-type exopeptidase activity(GO:0070008)
0.0 0.3 GO:0022820 potassium:chloride symporter activity(GO:0015379) potassium ion symporter activity(GO:0022820)
0.0 0.9 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.3 GO:0008349 MAP kinase kinase kinase kinase activity(GO:0008349)
0.0 0.5 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.2 GO:0005001 transmembrane receptor protein tyrosine phosphatase activity(GO:0005001) transmembrane receptor protein phosphatase activity(GO:0019198)
0.0 0.7 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 1.0 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.1 GO:0004454 ketohexokinase activity(GO:0004454)
0.0 0.2 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.0 0.2 GO:0003886 DNA (cytosine-5-)-methyltransferase activity(GO:0003886)
0.0 0.3 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.8 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.1 GO:0008427 calcium-dependent protein kinase inhibitor activity(GO:0008427) calcium-dependent protein kinase regulator activity(GO:0010858)
0.0 0.2 GO:0017034 Rap guanyl-nucleotide exchange factor activity(GO:0017034)
0.0 0.0 GO:0031370 eukaryotic initiation factor 4G binding(GO:0031370)
0.0 0.4 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.1 GO:0071535 RING-like zinc finger domain binding(GO:0071535)
0.0 0.6 GO:0005086 ARF guanyl-nucleotide exchange factor activity(GO:0005086)
0.0 0.5 GO:0042605 peptide antigen binding(GO:0042605)
0.0 0.2 GO:0016004 phospholipase activator activity(GO:0016004)
0.0 0.8 GO:0016776 phosphotransferase activity, phosphate group as acceptor(GO:0016776)
0.0 0.2 GO:0048185 activin binding(GO:0048185)
0.0 0.2 GO:0016857 racemase and epimerase activity, acting on carbohydrates and derivatives(GO:0016857)
0.0 0.3 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.3 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.0 0.3 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.1 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.5 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.1 GO:0019158 fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0 0.8 GO:0050661 NADP binding(GO:0050661)
0.0 0.2 GO:0005247 voltage-gated chloride channel activity(GO:0005247)
0.0 0.1 GO:0016427 tRNA (cytosine) methyltransferase activity(GO:0016427)
0.0 0.8 GO:0031491 nucleosome binding(GO:0031491)
0.0 0.1 GO:0015319 sodium:inorganic phosphate symporter activity(GO:0015319)
0.0 0.5 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631) ubiquitin-like protein conjugating enzyme activity(GO:0061650)
0.0 0.3 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors(GO:0016675) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.5 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.2 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.6 PID ARF 3PATHWAY Arf1 pathway
0.0 0.5 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.1 PID FOXO PATHWAY FoxO family signaling
0.0 0.4 PID IL5 PATHWAY IL5-mediated signaling events
0.0 0.4 PID MYC PATHWAY C-MYC pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 2.0 REACTOME PTM GAMMA CARBOXYLATION HYPUSINE FORMATION AND ARYLSULFATASE ACTIVATION Genes involved in PTM: gamma carboxylation, hypusine formation and arylsulfatase activation
0.1 1.0 REACTOME N GLYCAN TRIMMING IN THE ER AND CALNEXIN CALRETICULIN CYCLE Genes involved in N-glycan trimming in the ER and Calnexin/Calreticulin cycle
0.0 0.7 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.8 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.8 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.5 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 0.4 REACTOME COPI MEDIATED TRANSPORT Genes involved in COPI Mediated Transport
0.0 0.6 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.8 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.6 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.9 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)
0.0 1.5 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.9 REACTOME RNA POL I TRANSCRIPTION INITIATION Genes involved in RNA Polymerase I Transcription Initiation
0.0 1.2 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 0.4 REACTOME DESTABILIZATION OF MRNA BY BRF1 Genes involved in Destabilization of mRNA by Butyrate Response Factor 1 (BRF1)
0.0 0.7 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.9 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 0.3 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation
0.0 1.2 REACTOME INTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Intrinsic Pathway for Apoptosis
0.0 0.3 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.5 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.2 REACTOME HYALURONAN UPTAKE AND DEGRADATION Genes involved in Hyaluronan uptake and degradation
0.0 0.4 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 1.1 REACTOME ER PHAGOSOME PATHWAY Genes involved in ER-Phagosome pathway
0.0 0.2 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.0 0.5 REACTOME GLYCOSPHINGOLIPID METABOLISM Genes involved in Glycosphingolipid metabolism
0.0 0.1 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.0 0.2 REACTOME AUTODEGRADATION OF CDH1 BY CDH1 APC C Genes involved in Autodegradation of Cdh1 by Cdh1:APC/C
0.0 1.0 REACTOME ASPARAGINE N LINKED GLYCOSYLATION Genes involved in Asparagine N-linked glycosylation