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avrg: GFI1 WT vs 36n/n vs KD

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Results for Batf

Z-value: 0.86

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Transcription factors associated with Batf

Gene Symbol Gene ID Gene Info
Batf
ENSMUSG00000034266.7 basic leucine zipper transcription factor, ATF-like

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Batfmm39_v1_chr12_+_85733415_85733478-0.098.8e-01Click!

Activity profile of Batf motif

Sorted Z-values of Batf motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr13_-_21964747 1.18 ENSMUST00000080511.3
H1f5
H1.5 linker histone, cluster member
chr4_-_118795809 0.71 ENSMUST00000215312.3
Olfr1328
olfactory receptor 1328
chrX_-_20955370 0.63 ENSMUST00000040667.13
Zfp300
zinc finger protein 300
chr2_+_88470886 0.63 ENSMUST00000217379.2
ENSMUST00000120598.3
Olfr1191-ps1
olfactory receptor 1191, pseudogene 1
chr14_-_32907446 0.62 ENSMUST00000159606.2
Wdfy4
WD repeat and FYVE domain containing 4
chr9_+_75682637 0.55 ENSMUST00000012281.8
Bmp5
bone morphogenetic protein 5
chr2_+_88285211 0.54 ENSMUST00000219871.2
ENSMUST00000213115.3
Olfr1183
olfactory receptor 1183
chr7_-_85895409 0.52 ENSMUST00000165771.2
ENSMUST00000233075.2
ENSMUST00000233317.2
ENSMUST00000233312.2
ENSMUST00000233928.2
ENSMUST00000232799.2
ENSMUST00000233744.2
Vmn2r76
vomeronasal 2, receptor 76
chr18_+_82929451 0.50 ENSMUST00000235902.2
Zfp516
zinc finger protein 516
chr9_+_37995368 0.50 ENSMUST00000212502.4
Olfr887
olfactory receptor 887
chr11_-_78950698 0.47 ENSMUST00000141409.8
Ksr1
kinase suppressor of ras 1
chr1_+_107456731 0.46 ENSMUST00000182198.8
Serpinb10
serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 10
chr9_+_38026494 0.42 ENSMUST00000217286.2
Olfr889
olfactory receptor 889
chr18_+_82928782 0.41 ENSMUST00000235793.2
Zfp516
zinc finger protein 516
chr2_+_71884943 0.40 ENSMUST00000028525.6
Rapgef4
Rap guanine nucleotide exchange factor (GEF) 4
chr6_-_122833109 0.34 ENSMUST00000042081.9
C3ar1
complement component 3a receptor 1
chr2_-_111843053 0.33 ENSMUST00000213559.3
Olfr1310
olfactory receptor 1310
chr18_+_82928959 0.32 ENSMUST00000171238.8
Zfp516
zinc finger protein 516
chr9_+_106247943 0.32 ENSMUST00000173748.2
Dusp7
dual specificity phosphatase 7
chr14_+_45588632 0.31 ENSMUST00000228818.2
Styx
serine/threonine/tyrosine interaction protein
chr16_-_59421342 0.28 ENSMUST00000172910.3
Crybg3
beta-gamma crystallin domain containing 3
chr9_+_123921573 0.28 ENSMUST00000111442.3
ENSMUST00000171499.3
Ccr5
chemokine (C-C motif) receptor 5
chr6_-_97436223 0.27 ENSMUST00000113359.8
Frmd4b
FERM domain containing 4B
chr11_-_97913420 0.24 ENSMUST00000103144.10
ENSMUST00000017552.13
ENSMUST00000092736.11
ENSMUST00000107562.2
Cacnb1
calcium channel, voltage-dependent, beta 1 subunit
chr13_+_120085355 0.24 ENSMUST00000099241.4
Ccl28
chemokine (C-C motif) ligand 28
chr12_+_71062733 0.23 ENSMUST00000046305.12
Arid4a
AT rich interactive domain 4A (RBP1-like)
chr19_-_56810593 0.23 ENSMUST00000118592.8
Ccdc186
coiled-coil domain containing 186
chr8_+_109429732 0.22 ENSMUST00000188994.2
Zfhx3
zinc finger homeobox 3
chrX_-_104919201 0.19 ENSMUST00000198209.2
Atrx
ATRX, chromatin remodeler
chr1_-_171476559 0.19 ENSMUST00000111276.9
ENSMUST00000194531.6
Slamf7
SLAM family member 7
chr3_-_37286714 0.19 ENSMUST00000161015.2
ENSMUST00000029273.8
Il21
interleukin 21
chr11_+_75542902 0.17 ENSMUST00000102504.10
Myo1c
myosin IC
chr18_+_42408418 0.17 ENSMUST00000091920.6
ENSMUST00000046972.14
ENSMUST00000236240.2
Rbm27
RNA binding motif protein 27
chr3_-_79439181 0.16 ENSMUST00000239298.2
Fnip2
folliculin interacting protein 2
chr7_-_12829100 0.15 ENSMUST00000209822.3
ENSMUST00000235753.2
Vmn1r85
vomeronasal 1 receptor 85
chr12_+_83678987 0.15 ENSMUST00000048155.16
ENSMUST00000182618.8
ENSMUST00000183154.8
ENSMUST00000182036.8
ENSMUST00000182347.8
Rbm25
RNA binding motif protein 25
chr13_+_20295672 0.14 ENSMUST00000180626.2
Elmo1
engulfment and cell motility 1
chr10_+_128542120 0.14 ENSMUST00000054125.9
Pmel
premelanosome protein
chr5_-_86666408 0.13 ENSMUST00000140095.2
ENSMUST00000134179.8
Tmprss11g
transmembrane protease, serine 11g
chr17_+_48080113 0.13 ENSMUST00000160373.8
ENSMUST00000159641.8
Tfeb
transcription factor EB
chr4_-_155953849 0.11 ENSMUST00000030950.8
Cptp
ceramide-1-phosphate transfer protein
chrX_-_104918911 0.10 ENSMUST00000200471.2
Atrx
ATRX, chromatin remodeler
chr18_-_38131766 0.10 ENSMUST00000236588.2
ENSMUST00000237272.2
ENSMUST00000236134.2
Arap3
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
chr6_-_141892517 0.10 ENSMUST00000168119.8
Slco1a1
solute carrier organic anion transporter family, member 1a1
chr4_-_123466853 0.10 ENSMUST00000238555.2
Macf1
microtubule-actin crosslinking factor 1
chr19_-_12093187 0.09 ENSMUST00000208391.3
ENSMUST00000214103.2
Olfr1428
olfactory receptor 1428
chr10_+_129219952 0.09 ENSMUST00000214064.2
Olfr784
olfactory receptor 784
chr1_+_180978491 0.08 ENSMUST00000134115.8
ENSMUST00000111059.2
Cnih4
cornichon family AMPA receptor auxiliary protein 4
chr9_-_44179479 0.08 ENSMUST00000213803.2
Nlrx1
NLR family member X1
chr17_+_38082190 0.08 ENSMUST00000217119.2
Olfr122
olfactory receptor 122
chr11_-_78950641 0.06 ENSMUST00000226282.2
Ksr1
kinase suppressor of ras 1
chr16_-_19241884 0.04 ENSMUST00000206110.4
Olfr165
olfactory receptor 165
chr3_+_103034843 0.04 ENSMUST00000172288.3
Dennd2c
DENN/MADD domain containing 2C
chr5_+_67473069 0.04 ENSMUST00000202770.2
Slc30a9
solute carrier family 30 (zinc transporter), member 9
chr14_+_26789345 0.03 ENSMUST00000226105.2
Il17rd
interleukin 17 receptor D
chr12_-_115258124 0.03 ENSMUST00000192591.2
Ighv8-8
immunoglobulin heavy variable 8-8
chr7_-_142215027 0.03 ENSMUST00000105936.8
Igf2
insulin-like growth factor 2
chr9_-_39914761 0.02 ENSMUST00000215523.2
Olfr979
olfactory receptor 979
chr10_-_117074501 0.02 ENSMUST00000159193.8
ENSMUST00000020392.5
9530003J23Rik
RIKEN cDNA 9530003J23 gene
chr7_+_102834996 0.02 ENSMUST00000218618.2
Olfr592
olfactory receptor 592
chr16_+_35590745 0.01 ENSMUST00000231579.2
Hspbap1
Hspb associated protein 1
chr2_-_126625343 0.01 ENSMUST00000028842.9
ENSMUST00000130356.3
Usp50
ubiquitin specific peptidase 50
chr5_+_137759934 0.01 ENSMUST00000110983.3
ENSMUST00000031738.5
Tsc22d4
TSC22 domain family, member 4
chr2_-_36995660 0.01 ENSMUST00000100144.2
Olfr362
olfactory receptor 362
chrX_+_73636285 0.01 ENSMUST00000216108.2
ENSMUST00000216007.2
Olfr1325
olfactory receptor 1325
chr2_-_74409723 0.01 ENSMUST00000130586.8
Lnpk
lunapark, ER junction formation factor
chr9_+_7272514 0.00 ENSMUST00000015394.10
Mmp13
matrix metallopeptidase 13
chr18_+_82929037 0.00 ENSMUST00000236858.2
Zfp516
zinc finger protein 516
chr7_+_98092628 0.00 ENSMUST00000098274.5
Gucy2d
guanylate cyclase 2d
chr7_-_102408573 0.00 ENSMUST00000210453.3
ENSMUST00000232246.3
ENSMUST00000239110.2
ENSMUST00000060187.15
ENSMUST00000168007.3
Olfr560
Olfr78
olfactory receptor 560
olfactory receptor 78
chr14_+_55459462 0.00 ENSMUST00000022820.12
Dhrs2
dehydrogenase/reductase member 2
chr17_-_31383976 0.00 ENSMUST00000235870.2
Tff1
trefoil factor 1
chr12_+_86516875 0.00 ENSMUST00000167891.2
Esrrb
estrogen related receptor, beta
chrY_-_13465579 0.00 ENSMUST00000178428.2
Gm21866
predicted gene, 21866
chr6_-_40917431 0.00 ENSMUST00000122181.8
ENSMUST00000031935.10
1700074P13Rik
RIKEN cDNA 1700074P13 gene

Network of associatons between targets according to the STRING database.

First level regulatory network of Batf

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0021502 neural fold elevation formation(GO:0021502)
0.1 0.3 GO:0045204 MAPK export from nucleus(GO:0045204)
0.1 0.4 GO:1904457 positive regulation of neuronal action potential(GO:1904457)
0.1 0.2 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
0.1 0.3 GO:0060139 positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation of apoptotic process by virus(GO:0060139)
0.0 0.3 GO:0097394 post-embryonic appendage morphogenesis(GO:0035120) post-embryonic limb morphogenesis(GO:0035127) post-embryonic forelimb morphogenesis(GO:0035128) telomeric repeat-containing RNA transcription(GO:0097393) telomeric repeat-containing RNA transcription from RNA pol II promoter(GO:0097394) regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901580) negative regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901581) positive regulation of telomeric RNA transcription from RNA pol II promoter(GO:1901582)
0.0 0.3 GO:0002461 tolerance induction dependent upon immune response(GO:0002461)
0.0 0.2 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.0 0.1 GO:0035627 ceramide transport(GO:0035627)
0.0 0.1 GO:0009816 defense response to bacterium, incompatible interaction(GO:0009816) regulation of defense response to bacterium, incompatible interaction(GO:1902477)
0.0 0.2 GO:0002729 positive regulation of natural killer cell cytokine production(GO:0002729)
0.0 0.2 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.0 0.2 GO:1900748 positive regulation of vascular endothelial growth factor signaling pathway(GO:1900748)
0.0 1.0 GO:0009409 response to cold(GO:0009409)
0.0 0.1 GO:0035021 negative regulation of Rac protein signal transduction(GO:0035021)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0044316 cone cell pedicle(GO:0044316)
0.0 0.3 GO:1990707 subtelomeric heterochromatin(GO:1990421) nuclear subtelomeric heterochromatin(GO:1990707)
0.0 0.2 GO:0045160 myosin I complex(GO:0045160)
0.0 0.1 GO:0032585 multivesicular body membrane(GO:0032585)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 GO:0070700 BMP receptor binding(GO:0070700)
0.0 0.3 GO:0015616 DNA translocase activity(GO:0015616)
0.0 0.3 GO:0004875 complement receptor activity(GO:0004875)
0.0 0.2 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.0 0.5 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.2 GO:0042030 ATPase inhibitor activity(GO:0042030)
0.0 0.1 GO:0097001 ceramide binding(GO:0097001)
0.0 0.3 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.3 GO:0019957 C-C chemokine binding(GO:0019957)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.0 0.3 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated