avrg: GFI1 WT vs 36n/n vs KD

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
• Expression table
• Download the whole report

Gene Symbol	Gene ID	Gene Info
Bhlhe40 Links Ensembl NCBI MGI UniProt	ENSMUSG00000030103.12	basic helix-loop-helix family, member e40

Gene	Promoter	Pearson corr. coef.	P-value	Plot
Bhlhe40	mm39_v1_chr6_+_108637816_108637835	0.58	3.1e-01	Click!

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr4_+_148123490 Show fit	0.34	ENSMUST00000097788.11	Mthfr Links Ensembl NCBI MGI UniProt Show fit	methylenetetrahydrofolate reductase
chr4_-_148123223 Show fit	0.20	ENSMUST00000030879.12 ENSMUST00000137724.8	Clcn6 Links Ensembl NCBI MGI UniProt Show fit	chloride channel, voltage-sensitive 6
chr4_-_136776006 Show fit	0.15	ENSMUST00000049583.8	Zbtb40 Links Ensembl NCBI MGI UniProt Show fit	zinc finger and BTB domain containing 40
chr17_-_12988492 Show fit	0.14	ENSMUST00000024599.14	Igf2r Links Ensembl NCBI MGI UniProt Show fit	insulin-like growth factor 2 receptor
chr8_+_85763780 Show fit	0.14	ENSMUST00000211601.2 ENSMUST00000166592.2	Tnpo2 Links Ensembl NCBI MGI UniProt Show fit	transportin 2 (importin 3, karyopherin beta 2b)
chr8_+_85763534 Show fit	0.14	ENSMUST00000093360.12	Tnpo2 Links Ensembl NCBI MGI UniProt Show fit	transportin 2 (importin 3, karyopherin beta 2b)
chr5_+_123390149 Show fit	0.12	ENSMUST00000121964.8	Wdr66 Links Ensembl NCBI MGI UniProt Show fit	WD repeat domain 66
chr3_-_95014090 Show fit	0.12	ENSMUST00000005768.8 ENSMUST00000107232.9 ENSMUST00000107236.9	Pip5k1a Links Ensembl NCBI MGI UniProt Show fit	phosphatidylinositol-4-phosphate 5-kinase, type 1 alpha
chr5_-_137531463 Show fit	0.12	ENSMUST00000170293.8	Gnb2 Links Ensembl NCBI MGI UniProt Show fit	guanine nucleotide binding protein (G protein), beta 2
chr11_+_75239259 Show fit	0.12	ENSMUST00000044530.3	Smyd4 Links Ensembl NCBI MGI UniProt Show fit	SET and MYND domain containing 4
chr12_+_3476857 Show fit	0.12	ENSMUST00000111215.10 ENSMUST00000092003.12 ENSMUST00000144247.9 ENSMUST00000153102.9	Asxl2 Links Ensembl NCBI MGI UniProt Show fit	ASXL transcriptional regulator 2
chr14_+_51162425 Show fit	0.11	ENSMUST00000049411.12 ENSMUST00000136753.8 ENSMUST00000154288.3	Apex1 Links Ensembl NCBI MGI UniProt Show fit	apurinic/apyrimidinic endonuclease 1
chr4_-_119279551 Show fit	0.10	ENSMUST00000106316.2 ENSMUST00000030385.13	Ppcs Links Ensembl NCBI MGI UniProt Show fit	phosphopantothenoylcysteine synthetase
chr11_+_55095144 Show fit	0.10	ENSMUST00000108872.9 ENSMUST00000147506.8 ENSMUST00000020499.14	Slc36a1 Links Ensembl NCBI MGI UniProt Show fit	solute carrier family 36 (proton/amino acid symporter), member 1
chr8_+_3550533 Show fit	0.10	ENSMUST00000208306.2	Mcoln1 Links Ensembl NCBI MGI UniProt Show fit	mucolipin 1
chr5_+_104194383 Show fit	0.10	ENSMUST00000150226.8	Nudt9 Links Ensembl NCBI MGI UniProt Show fit	nudix (nucleoside diphosphate linked moiety X)-type motif 9
chr5_-_137531413 Show fit	0.09	ENSMUST00000168746.8	Gnb2 Links Ensembl NCBI MGI UniProt Show fit	guanine nucleotide binding protein (G protein), beta 2
chr9_-_44272923 Show fit	0.09	ENSMUST00000034644.10	Vps11 Links Ensembl NCBI MGI UniProt Show fit	VPS11, CORVET/HOPS core subunit
chr3_-_95014218 Show fit	0.09	ENSMUST00000107233.9	Pip5k1a Links Ensembl NCBI MGI UniProt Show fit	phosphatidylinositol-4-phosphate 5-kinase, type 1 alpha
chr14_-_51162346 Show fit	0.08	ENSMUST00000159292.8	Osgep Links Ensembl NCBI MGI UniProt Show fit	O-sialoglycoprotein endopeptidase
chr16_+_8647959 Show fit	0.08	ENSMUST00000023150.7	1810013L24Rik Links Ensembl NCBI MGI UniProt Show fit	RIKEN cDNA 1810013L24 gene
chr10_+_78410803 Show fit	0.07	ENSMUST00000218763.2 ENSMUST00000220430.2 ENSMUST00000218885.2 ENSMUST00000218215.2 ENSMUST00000218271.2	Ilvbl Links Ensembl NCBI MGI UniProt Show fit	ilvB (bacterial acetolactate synthase)-like
chr6_+_116314975 Show fit	0.07	ENSMUST00000079012.13 ENSMUST00000101032.10 ENSMUST00000123405.8 ENSMUST00000204657.3 ENSMUST00000203116.2 ENSMUST00000203193.3 ENSMUST00000126376.8	Marchf8 Links Ensembl NCBI MGI UniProt Show fit	membrane associated ring-CH-type finger 8
chr6_+_17694003 Show fit	0.07	ENSMUST00000052113.12 ENSMUST00000081635.13	St7 Links Ensembl NCBI MGI UniProt Show fit	suppression of tumorigenicity 7
chr10_-_17898838 Show fit	0.07	ENSMUST00000220433.2	Abracl Links Ensembl NCBI MGI UniProt Show fit	ABRA C-terminal like
chr8_+_111760521 Show fit	0.07	ENSMUST00000034441.8	Aars Links Ensembl NCBI MGI UniProt Show fit	alanyl-tRNA synthetase
chr14_+_51162635 Show fit	0.07	ENSMUST00000128395.2	Apex1 Links Ensembl NCBI MGI UniProt Show fit	apurinic/apyrimidinic endonuclease 1
chr8_+_85415935 Show fit	0.07	ENSMUST00000125370.10 ENSMUST00000175784.2	Trmt1 Links Ensembl NCBI MGI UniProt Show fit	tRNA methyltransferase 1
chr15_+_80139371 Show fit	0.07	ENSMUST00000109605.5 ENSMUST00000229828.2	Atf4 Links Ensembl NCBI MGI UniProt Show fit	activating transcription factor 4
chr5_-_72325482 Show fit	0.07	ENSMUST00000196241.2 ENSMUST00000013693.11	Commd8 Links Ensembl NCBI MGI UniProt Show fit	COMM domain containing 8
chr6_+_17694153 Show fit	0.07	ENSMUST00000115418.8	St7 Links Ensembl NCBI MGI UniProt Show fit	suppression of tumorigenicity 7
chr12_+_86994117 Show fit	0.06	ENSMUST00000187814.7 ENSMUST00000038369.11	Cipc Links Ensembl NCBI MGI UniProt Show fit	CLOCK interacting protein, circadian
chr11_+_3599183 Show fit	0.06	ENSMUST00000096441.5	Morc2a Links Ensembl NCBI MGI UniProt Show fit	microrchidia 2A
chr2_+_144210881 Show fit	0.06	ENSMUST00000028911.15 ENSMUST00000147747.8 ENSMUST00000183618.3	Kat14 Links Ensembl NCBI MGI UniProt Show fit Pet117 Links Ensembl NCBI MGI UniProt Show fit	lysine acetyltransferase 14 PET117 homolog
chr6_+_17693941 Show fit	0.06	ENSMUST00000115420.8 ENSMUST00000115419.8	St7 Links Ensembl NCBI MGI UniProt Show fit	suppression of tumorigenicity 7
chr5_-_123711098 Show fit	0.06	ENSMUST00000031388.13	Vps33a Links Ensembl NCBI MGI UniProt Show fit	VPS33A CORVET/HOPS core subunit
chr1_+_155034452 Show fit	0.06	ENSMUST00000027743.13 ENSMUST00000195302.6	Stx6 Links Ensembl NCBI MGI UniProt Show fit	syntaxin 6
chr16_+_4867876 Show fit	0.06	ENSMUST00000230703.2 ENSMUST00000052449.6	Ubn1 Links Ensembl NCBI MGI UniProt Show fit	ubinuclein 1
chr3_+_85481416 Show fit	0.05	ENSMUST00000107672.8 ENSMUST00000127348.8 ENSMUST00000107674.2	Gatb Links Ensembl NCBI MGI UniProt Show fit	glutamyl-tRNA(Gln) amidotransferase, subunit B
chr11_+_97340962 Show fit	0.05	ENSMUST00000107601.8	Arhgap23 Links Ensembl NCBI MGI UniProt Show fit	Rho GTPase activating protein 23
chr2_+_84669739 Show fit	0.05	ENSMUST00000146816.8 ENSMUST00000028469.14	Slc43a1 Links Ensembl NCBI MGI UniProt Show fit	solute carrier family 43, member 1
chr16_+_5051478 Show fit	0.05	ENSMUST00000100196.9 ENSMUST00000049207.9	Alg1 Links Ensembl NCBI MGI UniProt Show fit	asparagine-linked glycosylation 1 (beta-1,4-mannosyltransferase)
chr9_+_107879700 Show fit	0.05	ENSMUST00000035214.11 ENSMUST00000176854.7 ENSMUST00000175874.2	Ip6k1 Links Ensembl NCBI MGI UniProt Show fit	inositol hexaphosphate kinase 1
chr5_+_104194930 Show fit	0.05	ENSMUST00000134313.8	Nudt9 Links Ensembl NCBI MGI UniProt Show fit	nudix (nucleoside diphosphate linked moiety X)-type motif 9
chr5_+_65357034 Show fit	0.04	ENSMUST00000203653.3 ENSMUST00000041892.13	Wdr19 Links Ensembl NCBI MGI UniProt Show fit	WD repeat domain 19
chr7_-_35502392 Show fit	0.04	ENSMUST00000187282.3 ENSMUST00000205670.2 ENSMUST00000061586.11	Zfp507 Links Ensembl NCBI MGI UniProt Show fit	zinc finger protein 507
chr11_-_117671436 Show fit	0.04	ENSMUST00000026659.10 ENSMUST00000127227.2	Tmc6 Links Ensembl NCBI MGI UniProt Show fit	transmembrane channel-like gene family 6
chr11_-_75239084 Show fit	0.04	ENSMUST00000000767.6 ENSMUST00000092907.12	Rpa1 Links Ensembl NCBI MGI UniProt Show fit	replication protein A1
chr18_+_77153332 Show fit	0.04	ENSMUST00000114776.4 ENSMUST00000168882.9	Pias2 Links Ensembl NCBI MGI UniProt Show fit	protein inhibitor of activated STAT 2
chr12_-_84497718 Show fit	0.04	ENSMUST00000085192.7 ENSMUST00000220491.2	Aldh6a1 Links Ensembl NCBI MGI UniProt Show fit	aldehyde dehydrogenase family 6, subfamily A1
chr18_-_21029135 Show fit	0.04	ENSMUST00000097658.2 ENSMUST00000225661.3	Trappc8 Links Ensembl NCBI MGI UniProt Show fit	trafficking protein particle complex 8
chr11_-_75345482 Show fit	0.03	ENSMUST00000173320.8	Wdr81 Links Ensembl NCBI MGI UniProt Show fit	WD repeat domain 81
chr8_+_85415876 Show fit	0.03	ENSMUST00000109767.9 ENSMUST00000177084.8 ENSMUST00000109768.9 ENSMUST00000152301.9 ENSMUST00000177423.8	Trmt1 Links Ensembl NCBI MGI UniProt Show fit	tRNA methyltransferase 1
chr14_-_78774201 Show fit	0.03	ENSMUST00000123853.9	Akap11 Links Ensembl NCBI MGI UniProt Show fit	A kinase (PRKA) anchor protein 11
chrX_-_7054952 Show fit	0.03	ENSMUST00000004428.14	Clcn5 Links Ensembl NCBI MGI UniProt Show fit	chloride channel, voltage-sensitive 5
chr8_+_3550450 Show fit	0.03	ENSMUST00000004683.13 ENSMUST00000160338.2	Mcoln1 Links Ensembl NCBI MGI UniProt Show fit	mucolipin 1
chr18_+_77152890 Show fit	0.03	ENSMUST00000114777.10	Pias2 Links Ensembl NCBI MGI UniProt Show fit	protein inhibitor of activated STAT 2
chr1_+_87254729 Show fit	0.03	ENSMUST00000172794.8 ENSMUST00000164992.9 ENSMUST00000173173.8	Gigyf2 Links Ensembl NCBI MGI UniProt Show fit	GRB10 interacting GYF protein 2
chr14_-_51162083 Show fit	0.03	ENSMUST00000160375.8 ENSMUST00000162177.8	Osgep Links Ensembl NCBI MGI UniProt Show fit	O-sialoglycoprotein endopeptidase
chr7_-_82297676 Show fit	0.02	ENSMUST00000207693.2 ENSMUST00000056728.5 ENSMUST00000156720.8 ENSMUST00000126478.2	Saxo2 Links Ensembl NCBI MGI UniProt Show fit	stabilizer of axonemal microtubules 2
chr3_-_96634880 Show fit	0.02	ENSMUST00000029741.9	Polr3c Links Ensembl NCBI MGI UniProt Show fit	polymerase (RNA) III (DNA directed) polypeptide C
chr12_-_79343040 Show fit	0.02	ENSMUST00000218377.2 ENSMUST00000021547.8	Zfyve26 Links Ensembl NCBI MGI UniProt Show fit	zinc finger, FYVE domain containing 26
chr2_-_37312881 Show fit	0.02	ENSMUST00000112936.4 ENSMUST00000112934.8	Rc3h2 Links Ensembl NCBI MGI UniProt Show fit	ring finger and CCCH-type zinc finger domains 2
chr11_+_94544593 Show fit	0.02	ENSMUST00000025278.8	Mrpl27 Links Ensembl NCBI MGI UniProt Show fit	mitochondrial ribosomal protein L27
chr19_-_53378990 Show fit	0.02	ENSMUST00000025997.7	Smndc1 Links Ensembl NCBI MGI UniProt Show fit	survival motor neuron domain containing 1
chr16_+_43960183 Show fit	0.02	ENSMUST00000159514.8 ENSMUST00000161326.8 ENSMUST00000063520.15 ENSMUST00000063542.8	Naa50 Links Ensembl NCBI MGI UniProt Show fit	N(alpha)-acetyltransferase 50, NatE catalytic subunit
chr1_+_58432629 Show fit	0.02	ENSMUST00000186949.2	Bzw1 Links Ensembl NCBI MGI UniProt Show fit	basic leucine zipper and W2 domains 1
chr1_+_87254719 Show fit	0.02	ENSMUST00000027475.15	Gigyf2 Links Ensembl NCBI MGI UniProt Show fit	GRB10 interacting GYF protein 2
chr10_-_17898977 Show fit	0.02	ENSMUST00000020002.9	Abracl Links Ensembl NCBI MGI UniProt Show fit	ABRA C-terminal like
chr10_-_17898938 Show fit	0.02	ENSMUST00000220110.2	Abracl Links Ensembl NCBI MGI UniProt Show fit	ABRA C-terminal like
chrX_-_133501677 Show fit	0.02	ENSMUST00000239113.2	Gla Links Ensembl NCBI MGI UniProt Show fit	galactosidase, alpha
chr15_+_66449385 Show fit	0.01	ENSMUST00000230882.2 ENSMUST00000048188.10 ENSMUST00000230948.2 ENSMUST00000229160.2	Phf20l1 Links Ensembl NCBI MGI UniProt Show fit	PHD finger protein 20-like 1
chr15_+_84807582 Show fit	0.01	ENSMUST00000165443.4	Nup50 Links Ensembl NCBI MGI UniProt Show fit	nucleoporin 50
chrX_+_135039745 Show fit	0.01	ENSMUST00000116527.2	Bex4 Links Ensembl NCBI MGI UniProt Show fit	brain expressed X-linked 4
chr17_-_34043320 Show fit	0.01	ENSMUST00000173879.8 ENSMUST00000166693.3 ENSMUST00000173019.8	Rps28 Links Ensembl NCBI MGI UniProt Show fit	ribosomal protein S28
chr14_-_56137697 Show fit	0.01	ENSMUST00000111325.5	Sdr39u1 Links Ensembl NCBI MGI UniProt Show fit	short chain dehydrogenase/reductase family 39U, member 1
chr9_-_13738204 Show fit	0.01	ENSMUST00000147115.8	Cep57 Links Ensembl NCBI MGI UniProt Show fit	centrosomal protein 57
chr3_-_96634752 Show fit	0.01	ENSMUST00000154679.8	Polr3c Links Ensembl NCBI MGI UniProt Show fit	polymerase (RNA) III (DNA directed) polypeptide C
chr1_-_152642073 Show fit	0.01	ENSMUST00000111857.3	Rgl1 Links Ensembl NCBI MGI UniProt Show fit	ral guanine nucleotide dissociation stimulator,-like 1
chr19_-_4251589 Show fit	0.01	ENSMUST00000237923.2 ENSMUST00000025740.8 ENSMUST00000237723.2	Rad9a Links Ensembl NCBI MGI UniProt Show fit	RAD9 checkpoint clamp component A
chr11_+_95557783 Show fit	0.01	ENSMUST00000125172.8 ENSMUST00000036374.6	Phb Links Ensembl NCBI MGI UniProt Show fit	prohibitin
chr5_+_104194735 Show fit	0.01	ENSMUST00000031250.14	Nudt9 Links Ensembl NCBI MGI UniProt Show fit	nudix (nucleoside diphosphate linked moiety X)-type motif 9
chr1_-_152642032 Show fit	0.01	ENSMUST00000111859.8	Rgl1 Links Ensembl NCBI MGI UniProt Show fit	ral guanine nucleotide dissociation stimulator,-like 1
chr9_-_13738304 Show fit	0.01	ENSMUST00000148086.8 ENSMUST00000034398.12	Cep57 Links Ensembl NCBI MGI UniProt Show fit	centrosomal protein 57
chrX_+_152615221 Show fit	0.00	ENSMUST00000148708.2 ENSMUST00000123264.2 ENSMUST00000049999.9	Spin2c Links Ensembl NCBI MGI UniProt Show fit	spindlin family, member 2C
chr4_-_48473403 Show fit	0.00	ENSMUST00000164866.2 ENSMUST00000030030.15	Tex10 Links Ensembl NCBI MGI UniProt Show fit	testis expressed gene 10

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Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.2	GO:0046032	ADP catabolic process(GO:0046032)
0.0	0.2	GO:0070829	heterochromatin maintenance(GO:0070829)
0.0	0.1	GO:0002940	tRNA N2-guanine methylation(GO:0002940)
0.0	0.1	GO:0002949	tRNA threonylcarbamoyladenosine modification(GO:0002949)
0.0	0.3	GO:0006610	ribosomal protein import into nucleus(GO:0006610)
0.0	0.1	GO:0006419	alanyl-tRNA aminoacylation(GO:0006419)
0.0	0.1	GO:1900157	regulation of bone mineralization involved in bone maturation(GO:1900157)
0.0	0.1	GO:0070681	glutaminyl-tRNAGln biosynthesis via transamidation(GO:0070681)
0.0	0.1	GO:0036091	positive regulation of transcription from RNA polymerase II promoter in response to oxidative stress(GO:0036091)
0.0	0.2	GO:0043247	telomere maintenance in response to DNA damage(GO:0043247)
0.0	0.0	GO:0006208	pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.0	0.1	GO:0015808	L-alanine transport(GO:0015808)
0.0	0.1	GO:0035542	regulation of SNARE complex assembly(GO:0035542)
0.0	0.0	GO:0060830	ciliary receptor clustering involved in smoothened signaling pathway(GO:0060830) myotome development(GO:0061055)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.2	GO:0033263	CORVET complex(GO:0033263)
0.0	0.1	GO:0030956	glutamyl-tRNA(Gln) amidotransferase complex(GO:0030956)
0.0	0.1	GO:1990589	Lewy body core(GO:1990037) ATF4-CREB1 transcription factor complex(GO:1990589) ATF1-ATF4 transcription factor complex(GO:1990590)
0.0	0.1	GO:0000408	EKC/KEOPS complex(GO:0000408)
0.0	0.2	GO:0005847	mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.2	GO:0004489	methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.1	0.2	GO:0016890	site-specific endodeoxyribonuclease activity, specific for altered base(GO:0016890)
0.0	0.1	GO:0061711	N(6)-L-threonylcarbamoyladenine synthase(GO:0061711)
0.0	0.1	GO:0005302	L-tyrosine transmembrane transporter activity(GO:0005302)
0.0	0.1	GO:0072345	NAADP-sensitive calcium-release channel activity(GO:0072345)
0.0	0.2	GO:0016308	1-phosphatidylinositol-4-phosphate 5-kinase activity(GO:0016308)
0.0	0.1	GO:0004813	alanine-tRNA ligase activity(GO:0004813)
0.0	0.1	GO:0004809	tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.0	0.2	GO:0047631	ADP-ribose diphosphatase activity(GO:0047631)
0.0	0.1	GO:0050567	glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity(GO:0050567)
0.0	0.1	GO:0031995	insulin-like growth factor II binding(GO:0031995)
0.0	0.2	GO:0005247	voltage-gated chloride channel activity(GO:0005247)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.2	REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY	Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway