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avrg: GFI1 WT vs 36n/n vs KD

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Results for Cdc5l

Z-value: 0.80

Motif logo

Transcription factors associated with Cdc5l

Gene Symbol Gene ID Gene Info
ENSMUSG00000023932.10 cell division cycle 5-like (S. pombe)

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Cdc5lmm39_v1_chr17_-_45744637_45744671-0.503.9e-01Click!

Activity profile of Cdc5l motif

Sorted Z-values of Cdc5l motif

Promoter Log-likelihood Transcript Gene Gene Info
chr16_+_36004452 0.88 ENSMUST00000114858.2
cystatin domain containing 4
chr10_+_17598961 0.66 ENSMUST00000038107.9
ENSMUST00000219558.2
ENSMUST00000218370.2
Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2
chr4_-_55532453 0.46 ENSMUST00000132746.2
ENSMUST00000107619.3
Kruppel-like factor 4 (gut)
chr1_+_17672117 0.44 ENSMUST00000088476.4
peptidase inhibitor 15
chr6_+_6863269 0.38 ENSMUST00000171311.8
ENSMUST00000160937.9
distal-less homeobox 6
chr18_-_22983794 0.36 ENSMUST00000092015.11
ENSMUST00000069215.13
nucleolar protein 4
chr1_+_143516402 0.34 ENSMUST00000038252.4
UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 2
chr15_-_50746202 0.32 ENSMUST00000184885.8
transcriptional repressor GATA binding 1
chr7_-_104611827 0.26 ENSMUST00000214216.2
olfactory receptor 670
chr7_-_29898236 0.26 ENSMUST00000001845.13
calpain, small subunit 1
chrX_+_135723420 0.22 ENSMUST00000033800.13
proteolipid protein (myelin) 1
chr19_+_23881821 0.19 ENSMUST00000237688.2
amyloid beta (A4) precursor protein binding, family A, member 1
chr17_+_47451868 0.19 ENSMUST00000190080.9
transcriptional regulating factor 1
chr14_+_66872699 0.18 ENSMUST00000159365.8
ENSMUST00000054661.8
ENSMUST00000225182.2
ENSMUST00000159068.2
adrenergic receptor, alpha 1a
chrX_-_36368176 0.15 ENSMUST00000130324.2
UPF3 regulator of nonsense transcripts homolog B (yeast)
chr19_+_53128901 0.14 ENSMUST00000235754.2
ENSMUST00000237301.2
ENSMUST00000238130.2
adducin 3 (gamma)
chr7_-_101517874 0.13 ENSMUST00000150184.2
folate receptor 1 (adult)
chr7_+_5086702 0.12 ENSMUST00000208634.2
epsin 1
chr5_-_86666408 0.11 ENSMUST00000140095.2
ENSMUST00000134179.8
transmembrane protease, serine 11g
chr4_-_149211145 0.11 ENSMUST00000030815.3
cortistatin
chr11_+_97732108 0.10 ENSMUST00000155954.3
ENSMUST00000164364.2
ENSMUST00000170806.2
RIKEN cDNA B230217C12 gene
chr12_+_59176506 0.10 ENSMUST00000175912.8
ENSMUST00000176892.8
MIA SH3 domain ER export factor 2
chr3_-_122910662 0.09 ENSMUST00000051443.8
synaptopodin 2
chr19_+_53128861 0.09 ENSMUST00000111741.10
adducin 3 (gamma)
chr11_+_3152874 0.08 ENSMUST00000179770.8
ENSMUST00000110048.8
eukaryotic translation initiation factor 4E nuclear import factor 1
chr6_+_135339543 0.08 ENSMUST00000205156.3
epithelial membrane protein 1
chr5_+_104447037 0.07 ENSMUST00000031246.9
integrin binding sialoprotein
chr7_-_103390529 0.07 ENSMUST00000051346.5
olfactory receptor 629
chr12_+_59176543 0.07 ENSMUST00000069430.15
ENSMUST00000177370.8
MIA SH3 domain ER export factor 2
chr1_+_60785517 0.06 ENSMUST00000027165.3
CD28 antigen
chr5_+_88073438 0.06 ENSMUST00000001667.13
ENSMUST00000113267.8
casein kappa
chr5_-_138278223 0.06 ENSMUST00000014089.9
ENSMUST00000161827.8
glypican 2 (cerebroglycan)
chr13_-_18556626 0.06 ENSMUST00000139064.10
ENSMUST00000175703.9
POU domain, class 6, transcription factor 2
chr14_+_73475335 0.05 ENSMUST00000044405.8
lysophosphatidic acid receptor 6
chrX_+_135723531 0.04 ENSMUST00000113085.2
proteolipid protein (myelin) 1
chr15_-_13173736 0.02 ENSMUST00000036439.6
cadherin 6
chr2_+_125876566 0.02 ENSMUST00000064794.14
fibroblast growth factor 7
chr8_+_91681898 0.02 ENSMUST00000209746.2
chromodomain helicase DNA binding protein 9
chr2_+_125876883 0.02 ENSMUST00000110442.2
fibroblast growth factor 7
chr17_-_78991691 0.01 ENSMUST00000145480.2
striatin, calmodulin binding protein
chr10_+_20046748 0.01 ENSMUST00000215924.2
microtubule-associated protein 7
chrX_-_93410383 0.01 ENSMUST00000044989.12
family with sequence similarity 90, member A1B
chr14_+_52680447 0.01 ENSMUST00000205900.3
ENSMUST00000215030.2
ENSMUST00000206100.2
ENSMUST00000206718.2
olfactory receptor 1509
chr5_-_136911969 0.00 ENSMUST00000057497.13
ENSMUST00000111103.2
collagen, type XXVI, alpha 1
chr11_+_59197746 0.00 ENSMUST00000000128.10
ENSMUST00000108783.4
wingless-type MMTV integration site family, member 9A
chr2_+_106525938 0.00 ENSMUST00000016530.14
metallophosphoesterase domain containing 2
chr2_+_121991181 0.00 ENSMUST00000036089.8
tripartite motif-containing 69
chr4_-_119240885 0.00 ENSMUST00000238422.2
ENSMUST00000238719.2
ENSMUST00000238723.2
ENSMUST00000044781.9
ENSMUST00000084307.5
ENSMUST00000148236.9
ENSMUST00000127474.3
ENSMUST00000238704.2
coiled-coil domain containing 30
chr8_-_49009043 0.00 ENSMUST00000110343.3
teneurin transmembrane protein 3
chr2_-_85993291 0.00 ENSMUST00000099907.2
olfactory receptor 1043

Network of associatons between targets according to the STRING database.

First level regulatory network of Cdc5l

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0035801 adrenal cortex development(GO:0035801) adrenal cortex formation(GO:0035802)
0.1 0.5 GO:0045415 negative regulation of interleukin-8 biosynthetic process(GO:0045415)
0.0 0.3 GO:0006682 galactosylceramide biosynthetic process(GO:0006682) galactolipid biosynthetic process(GO:0019375)
0.0 0.2 GO:0001994 norepinephrine-epinephrine vasoconstriction involved in regulation of systemic arterial blood pressure(GO:0001994)
0.0 0.0 GO:0061033 secretion by lung epithelial cell involved in lung growth(GO:0061033)
0.0 0.1 GO:0061713 neural crest cell migration involved in heart formation(GO:0003147) anterior neural tube closure(GO:0061713) cellular response to folic acid(GO:0071231)
0.0 0.3 GO:0042759 long-chain fatty acid biosynthetic process(GO:0042759)
0.0 0.3 GO:1902043 positive regulation of extrinsic apoptotic signaling pathway via death domain receptors(GO:1902043)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0098890 extrinsic component of postsynaptic membrane(GO:0098890)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0001010 transcription factor activity, sequence-specific DNA binding transcription factor recruiting(GO:0001010)
0.1 0.2 GO:0004937 alpha1-adrenergic receptor activity(GO:0004937)
0.0 0.3 GO:0008499 UDP-galactose:beta-N-acetylglucosamine beta-1,3-galactosyltransferase activity(GO:0008499)
0.0 0.7 GO:0050693 LBD domain binding(GO:0050693)
0.0 0.3 GO:0019911 structural constituent of myelin sheath(GO:0019911)
0.0 0.1 GO:0051870 methotrexate binding(GO:0051870)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 PID HIF2PATHWAY HIF-2-alpha transcription factor network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 REACTOME SYNTHESIS SECRETION AND DEACYLATION OF GHRELIN Genes involved in Synthesis, Secretion, and Deacylation of Ghrelin