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avrg: GFI1 WT vs 36n/n vs KD

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Results for Cebpb

Z-value: 1.73

Motif logo

Transcription factors associated with Cebpb

Gene Symbol Gene ID Gene Info
ENSMUSG00000056501.4 CCAAT/enhancer binding protein (C/EBP), beta

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Cebpbmm39_v1_chr2_+_167530835_167530894-0.039.6e-01Click!

Activity profile of Cebpb motif

Sorted Z-values of Cebpb motif

Promoter Log-likelihood Transcript Gene Gene Info
chr9_-_109678685 3.35 ENSMUST00000112022.5
cathelicidin antimicrobial peptide
chr19_-_11618192 2.60 ENSMUST00000112984.4
membrane-spanning 4-domains, subfamily A, member 3
chr19_-_11618165 2.57 ENSMUST00000186023.7
membrane-spanning 4-domains, subfamily A, member 3
chr11_-_75313350 1.46 ENSMUST00000125982.2
ENSMUST00000137103.8
serine (or cysteine) peptidase inhibitor, clade F, member 1
chr11_-_75313412 1.42 ENSMUST00000138661.8
ENSMUST00000000769.14
serine (or cysteine) peptidase inhibitor, clade F, member 1
chr9_+_110248815 1.17 ENSMUST00000035061.9
neutrophilic granule protein
chr17_+_48653429 1.12 ENSMUST00000024791.15
triggering receptor expressed on myeloid cells 2
chr17_-_56428968 1.09 ENSMUST00000041357.9
leucine-rich alpha-2-glycoprotein 1
chr3_-_50398027 0.96 ENSMUST00000029297.6
ENSMUST00000194462.6
solute carrier family 7 (cationic amino acid transporter, y+ system), member 11
chr17_+_48653493 0.96 ENSMUST00000113237.4
triggering receptor expressed on myeloid cells 2
chr9_+_110867807 0.95 ENSMUST00000197575.2
lactotransferrin
chr6_-_56878854 0.95 ENSMUST00000101367.9
5'-nucleotidase, cytosolic III
chr9_+_107957640 0.88 ENSMUST00000162886.2
macrophage stimulating 1 (hepatocyte growth factor-like)
chr9_+_107957621 0.88 ENSMUST00000035211.14
macrophage stimulating 1 (hepatocyte growth factor-like)
chr4_-_136626073 0.87 ENSMUST00000046285.6
complement component 1, q subcomponent, alpha polypeptide
chr17_+_87270504 0.79 ENSMUST00000024956.15
ras homolog family member Q
chr4_+_152123772 0.78 ENSMUST00000084116.13
ENSMUST00000103197.5
nucleolar protein 9
chr4_+_150322151 0.77 ENSMUST00000141931.2
enolase 1, alpha non-neuron
chr10_+_80765900 0.72 ENSMUST00000015456.10
ENSMUST00000220246.2
growth arrest and DNA-damage-inducible 45 beta
chr3_+_106393348 0.70 ENSMUST00000183271.2
DENN/MADD domain containing 2D
chr1_+_134110142 0.69 ENSMUST00000082060.10
ENSMUST00000153856.8
ENSMUST00000133701.8
ENSMUST00000132873.8
chitinase-like 1
chr3_+_87814147 0.68 ENSMUST00000159492.8
heparin binding growth factor
chr7_-_46365108 0.65 ENSMUST00000006956.9
ENSMUST00000210913.2
serum amyloid A 3
chr7_-_107696793 0.65 ENSMUST00000217304.2
olfactory receptor 482
chr15_-_103218876 0.64 ENSMUST00000079824.6
G protein-coupled receptor 84
chr17_+_47908025 0.64 ENSMUST00000183206.2
cyclin D3
chr13_-_53135064 0.64 ENSMUST00000071065.8
nuclear factor, interleukin 3, regulated
chr7_+_120634834 0.62 ENSMUST00000207351.2
methyltransferase like 9
chr14_+_51181956 0.61 ENSMUST00000178092.2
ENSMUST00000227052.2
purine-nucleoside phosphorylase
predicted gene, 49342
chr13_+_25127127 0.60 ENSMUST00000021773.13
glycosylphosphatidylinositol specific phospholipase D1
chr13_+_49835576 0.59 ENSMUST00000165316.8
ENSMUST00000047363.14
isoleucine-tRNA synthetase
chr1_+_40123858 0.59 ENSMUST00000027243.13
interleukin 1 receptor, type II
chr7_-_45480200 0.56 ENSMUST00000107723.9
ENSMUST00000131384.3
glutamate-rich WD repeat containing 1
chr9_-_39405284 0.55 ENSMUST00000077757.7
ENSMUST00000215065.3
ENSMUST00000216316.3
olfactory receptor 44
chr8_-_46664321 0.53 ENSMUST00000034049.5
solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 4
chr5_+_135038006 0.53 ENSMUST00000111216.8
ENSMUST00000046999.12
abhydrolase domain containing 11
chr6_+_40605758 0.52 ENSMUST00000202636.4
ENSMUST00000201148.4
ENSMUST00000071535.10
maltase-glucoamylase
chr5_+_115417725 0.52 ENSMUST00000040421.11
coenzyme Q5 methyltransferase
chr2_+_119181703 0.49 ENSMUST00000028780.4
ChaC, cation transport regulator 1
chr2_-_3513783 0.48 ENSMUST00000124331.8
ENSMUST00000140494.2
ENSMUST00000027961.12
predicted gene 45902
heat shock protein 14
chr2_-_32278245 0.48 ENSMUST00000192241.2
lipocalin 2
chr10_+_79722081 0.47 ENSMUST00000046091.7
elastase, neutrophil expressed
chr18_-_64649497 0.47 ENSMUST00000237351.2
ENSMUST00000236186.2
ENSMUST00000235325.2
asparaginyl-tRNA synthetase
chr7_+_30463175 0.46 ENSMUST00000165887.8
ENSMUST00000085691.11
ENSMUST00000054427.13
ENSMUST00000085688.11
dermokine
chr6_-_11907392 0.45 ENSMUST00000204084.3
ENSMUST00000031637.8
ENSMUST00000204978.3
ENSMUST00000204714.2
Ndufa4, mitochondrial complex associated
chr7_-_45083688 0.45 ENSMUST00000210439.2
RuvB-like protein 2
chr7_-_126873219 0.45 ENSMUST00000082428.6
selenophosphate synthetase 2
chr11_-_45943138 0.44 ENSMUST00000093169.3
predicted gene 12166
chr5_+_31212165 0.44 ENSMUST00000202795.4
ENSMUST00000201182.4
ENSMUST00000200953.4
carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
chr19_-_15902292 0.44 ENSMUST00000025542.10
phosphoserine aminotransferase 1
chr8_+_111760521 0.43 ENSMUST00000034441.8
alanyl-tRNA synthetase
chr13_+_49835667 0.43 ENSMUST00000172254.3
isoleucine-tRNA synthetase
chr3_+_96011810 0.42 ENSMUST00000132980.8
ENSMUST00000138206.8
ENSMUST00000090785.9
ENSMUST00000035519.12
OTU domain containing 7B
chr5_+_31212110 0.41 ENSMUST00000013773.12
ENSMUST00000201838.4
carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
chr15_+_41694317 0.41 ENSMUST00000166917.3
ENSMUST00000230127.2
ENSMUST00000230131.2
oxidation resistance 1
chr17_+_34131696 0.41 ENSMUST00000174146.3
Fas death domain-associated protein
chr8_+_86219191 0.40 ENSMUST00000034136.12
glutamic pyruvate transaminase (alanine aminotransferase) 2
chr4_+_63262775 0.39 ENSMUST00000030044.3
orosomucoid 1
chr11_-_3321307 0.39 ENSMUST00000101640.10
ENSMUST00000101642.10
LIM motif-containing protein kinase 2
chr11_+_49141339 0.36 ENSMUST00000101293.11
mannoside acetylglucosaminyltransferase 1
chr8_+_26298502 0.35 ENSMUST00000033979.6
steroidogenic acute regulatory protein
chr2_-_164198427 0.35 ENSMUST00000109367.10
secretory leukocyte peptidase inhibitor
chr1_+_171173252 0.35 ENSMUST00000006579.5
prefoldin 2
chr1_+_171173237 0.35 ENSMUST00000135941.8
prefoldin 2
chr3_+_109481223 0.34 ENSMUST00000106576.3
vav 3 oncogene
chr17_+_87270707 0.34 ENSMUST00000139344.2
ras homolog family member Q
chr18_-_64649620 0.33 ENSMUST00000025483.11
ENSMUST00000237400.2
asparaginyl-tRNA synthetase
chr4_-_108690741 0.33 ENSMUST00000102740.8
ENSMUST00000102741.8
basic transcription factor 3-like 4
chr3_+_20011201 0.33 ENSMUST00000091309.12
ENSMUST00000108329.8
ENSMUST00000003714.13
ceruloplasmin
chr11_-_120521382 0.32 ENSMUST00000106181.8
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein G (avian)
chr1_-_131204651 0.32 ENSMUST00000161764.8
inhibitor of kappaB kinase epsilon
chr1_-_78465479 0.32 ENSMUST00000190441.2
ENSMUST00000170217.8
ENSMUST00000188247.7
ENSMUST00000068333.14
phenylalanyl-tRNA synthetase, beta subunit
chr10_+_127919142 0.31 ENSMUST00000026459.6
ATP synthase, H+ transporting mitochondrial F1 complex, beta subunit
chr19_+_55240357 0.31 ENSMUST00000225551.2
acyl-CoA synthetase long-chain family member 5
chr10_+_61556371 0.31 ENSMUST00000080099.6
apoptosis-inducing factor, mitochondrion-associated 2
chr17_+_28910302 0.30 ENSMUST00000004990.14
ENSMUST00000114754.8
ENSMUST00000062694.16
mitogen-activated protein kinase 14
chr2_-_152185901 0.30 ENSMUST00000040312.7
tribbles pseudokinase 3
chr3_-_121608859 0.30 ENSMUST00000029770.8
ATP-binding cassette, sub-family D (ALD), member 3
chr9_+_5298669 0.29 ENSMUST00000238505.2
caspase 1
chr3_+_31150982 0.29 ENSMUST00000118204.2
SKI-like
chr5_-_129856267 0.28 ENSMUST00000201394.4
phosphoserine phosphatase
chr19_-_8690330 0.28 ENSMUST00000206598.2
solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2
chr11_-_87716849 0.28 ENSMUST00000103177.10
lactoperoxidase
chr1_+_55170476 0.28 ENSMUST00000162553.2
MOB family member 4, phocein
chr5_-_137531413 0.28 ENSMUST00000168746.8
guanine nucleotide binding protein (G protein), beta 2
chr4_+_126915104 0.28 ENSMUST00000030623.8
splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated)
chr6_-_3968365 0.28 ENSMUST00000031674.11
tissue factor pathway inhibitor 2
chr11_-_120534469 0.28 ENSMUST00000141254.8
ENSMUST00000170556.8
ENSMUST00000151876.8
ENSMUST00000026133.15
ENSMUST00000139706.2
pyrroline-5-carboxylate reductase 1
chr11_+_106107752 0.27 ENSMUST00000021046.6
DEAD box helicase 42
chr7_-_44181477 0.27 ENSMUST00000098483.9
ENSMUST00000035323.6
Spi-B transcription factor (Spi-1/PU.1 related)
chr14_-_54648057 0.27 ENSMUST00000200545.2
ENSMUST00000227967.2
solute carrier family 7 (cationic amino acid transporter, y+ system), member 7
chr14_+_22069709 0.27 ENSMUST00000075639.11
leucine rich melanocyte differentiation associated
chr13_-_49462694 0.27 ENSMUST00000110087.9
FYVE, RhoGEF and PH domain containing 3
chr4_-_133694543 0.27 ENSMUST00000123234.8
high mobility group nucleosomal binding domain 2
chr4_-_43558386 0.26 ENSMUST00000130353.2
talin 1
chr4_-_151129020 0.26 ENSMUST00000103204.11
period circadian clock 3
chr11_-_101442663 0.25 ENSMUST00000017290.11
breast cancer 1, early onset
chr11_+_49141410 0.25 ENSMUST00000129588.2
mannoside acetylglucosaminyltransferase 1
chr4_-_130068902 0.25 ENSMUST00000105998.8
tubulointerstitial nephritis antigen-like 1
chr3_-_121608809 0.25 ENSMUST00000197383.5
ATP-binding cassette, sub-family D (ALD), member 3
chr17_+_27276262 0.24 ENSMUST00000049308.9
inositol 1,4,5-triphosphate receptor 3
chr11_-_72441054 0.24 ENSMUST00000021154.7
spinster homolog 3
chr5_+_93416091 0.24 ENSMUST00000121127.2
cyclin G2
chr5_-_123126550 0.24 ENSMUST00000086200.11
ENSMUST00000156474.8
lysine (K)-specific demethylase 2B
chr10_-_88192852 0.23 ENSMUST00000020249.2
DNA-damage regulated autophagy modulator 1
chr4_-_107928567 0.23 ENSMUST00000106701.2
sterol carrier protein 2, liver
chr11_-_86977576 0.22 ENSMUST00000020801.14
smg-8 homolog, nonsense mediated mRNA decay factor (C. elegans)
chr11_-_120520954 0.22 ENSMUST00000106180.2
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein G (avian)
chr9_-_103107460 0.22 ENSMUST00000165296.8
ENSMUST00000112645.8
transferrin
chr13_+_95460110 0.22 ENSMUST00000221807.2
zinc finger, BED type containing 3
chr11_-_84761472 0.21 ENSMUST00000018547.9
gametogenetin binding protein 2
chr2_+_25313240 0.21 ENSMUST00000134259.8
ENSMUST00000100320.5
fucosyltransferase 7
chr7_+_109617456 0.21 ENSMUST00000084731.5
importin 7
chr2_+_103858168 0.20 ENSMUST00000111135.8
ENSMUST00000111136.8
ENSMUST00000102565.4
F-box protein 3
chr6_-_87786736 0.20 ENSMUST00000032134.9
RAB43, member RAS oncogene family
chr7_-_109092834 0.19 ENSMUST00000106739.8
tripartite motif-containing 66
chr19_-_8796288 0.19 ENSMUST00000153281.2
tetratricopeptide repeat domain 9C
chr14_-_55108384 0.19 ENSMUST00000146642.2
homeodomain leucine zipper-encoding gene
chr11_-_102120953 0.19 ENSMUST00000107150.8
ENSMUST00000156337.2
ENSMUST00000107151.9
ENSMUST00000107152.9
histone deacetylase 5
chr2_+_103858066 0.19 ENSMUST00000028603.10
F-box protein 3
chr13_-_117161921 0.18 ENSMUST00000223949.2
poly (ADP-ribose) polymerase family, member 8
chr13_+_51254852 0.18 ENSMUST00000095797.6
spindlin 1
chr11_-_102120917 0.18 ENSMUST00000008999.12
histone deacetylase 5
chr7_+_45084300 0.18 ENSMUST00000211150.2
glycogen synthase 1, muscle
chr6_-_123266820 0.18 ENSMUST00000032239.11
ENSMUST00000177367.8
C-type lectin domain family 4, member e
chr14_+_31887739 0.17 ENSMUST00000111994.10
ENSMUST00000168114.8
ENSMUST00000168034.8
nuclear receptor coactivator 4
chr8_+_94763826 0.17 ENSMUST00000109556.9
ENSMUST00000093301.9
ENSMUST00000060632.8
2-oxoglutarate and iron-dependent oxygenase domain containing 1
chr14_-_54647647 0.16 ENSMUST00000228488.2
ENSMUST00000195970.5
solute carrier family 7 (cationic amino acid transporter, y+ system), member 7
chr19_+_12438125 0.16 ENSMUST00000081035.9
macrophage expressed gene 1
chr2_-_129213050 0.16 ENSMUST00000028881.14
interleukin 1 beta
chr17_+_29333116 0.16 ENSMUST00000233717.2
ENSMUST00000141239.2
RAB44, member RAS oncogene family
chr7_+_18915086 0.16 ENSMUST00000120595.8
ENSMUST00000048502.10
echinoderm microtubule associated protein like 2
chr11_-_6150411 0.15 ENSMUST00000066496.10
NudC domain containing 3
chr15_+_37233280 0.15 ENSMUST00000161405.8
ENSMUST00000022895.15
ENSMUST00000161532.2
grainyhead like transcription factor 2
chr7_-_45084012 0.15 ENSMUST00000107771.12
ENSMUST00000211666.2
RuvB-like protein 2
chr11_-_84761538 0.15 ENSMUST00000170741.2
ENSMUST00000172405.8
ENSMUST00000100686.10
ENSMUST00000108081.9
gametogenetin binding protein 2
chr11_-_84761637 0.15 ENSMUST00000168434.8
gametogenetin binding protein 2
chr2_+_15531281 0.15 ENSMUST00000146205.3
MAM and LDL receptor class A domain containing 1
chr1_+_55170411 0.14 ENSMUST00000027122.14
MOB family member 4, phocein
chr1_-_171173168 0.14 ENSMUST00000156856.8
ENSMUST00000111296.8
nitrilase 1
chr12_-_113843161 0.14 ENSMUST00000103451.5
immunoglobulin heavy variable 2-9
chr1_-_79838897 0.14 ENSMUST00000190724.2
serine (or cysteine) peptidase inhibitor, clade E, member 2
chr9_-_71678814 0.13 ENSMUST00000122065.2
ENSMUST00000121322.8
ENSMUST00000072899.9
cingulin-like 1
chr17_-_57501170 0.13 ENSMUST00000005976.8
tumor necrosis factor (ligand) superfamily, member 14
chr3_+_146110709 0.13 ENSMUST00000129978.2
synovial sarcoma, X 2 interacting protein
chr19_-_8796677 0.13 ENSMUST00000096751.11
tetratricopeptide repeat domain 9C
chr4_+_155646807 0.13 ENSMUST00000030939.14
NAD kinase
chrX_-_56384089 0.12 ENSMUST00000033468.11
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr13_-_117162041 0.12 ENSMUST00000022239.8
poly (ADP-ribose) polymerase family, member 8
chrX_-_133501874 0.12 ENSMUST00000033621.8
galactosidase, alpha
chr3_+_66127330 0.12 ENSMUST00000029421.6
pentraxin related gene
chr19_+_6451667 0.12 ENSMUST00000113471.3
ENSMUST00000113469.3
RAS, guanyl releasing protein 2
chr10_-_99595498 0.12 ENSMUST00000056085.6
citrate synthase like
chr10_-_8632519 0.12 ENSMUST00000212869.2
SAM and SH3 domain containing 1
chr1_+_55170390 0.11 ENSMUST00000159311.8
ENSMUST00000162364.8
MOB family member 4, phocein
chr7_+_30475819 0.11 ENSMUST00000041703.10
dermokine
chr14_-_68893253 0.11 ENSMUST00000225767.3
ENSMUST00000111072.8
ENSMUST00000022642.6
ENSMUST00000224039.2
a disintegrin and metallopeptidase domain 28
chr17_+_35863025 0.11 ENSMUST00000044804.8
corneodesmosin
chr11_-_99383938 0.11 ENSMUST00000006969.8
keratin 23
chr8_+_10056654 0.10 ENSMUST00000033892.9
tumor necrosis factor (ligand) superfamily, member 13b
chr7_+_78563150 0.10 ENSMUST00000118867.8
interferon-stimulated protein
chr4_-_148172423 0.10 ENSMUST00000030865.9
angiotensin II, type I receptor-associated protein
chr10_+_127126643 0.10 ENSMUST00000026475.15
ENSMUST00000139091.2
ENSMUST00000230446.2
DNA-damage inducible transcript 3
DNA-damage inducible transcript 3
chr12_-_101784727 0.10 ENSMUST00000222587.2
fibulin 5
chr12_+_24622274 0.09 ENSMUST00000085553.13
grainyhead like transcription factor 1
chr4_-_130253703 0.09 ENSMUST00000134159.3
zinc finger, CCHC domain containing 17
chr14_-_49304110 0.09 ENSMUST00000162175.9
exocyst complex component 5
chr7_+_18915136 0.09 ENSMUST00000144054.8
ENSMUST00000141718.8
echinoderm microtubule associated protein like 2
chr1_+_128079543 0.08 ENSMUST00000189317.3
R3H domain containing 1
chr3_+_103739877 0.08 ENSMUST00000062945.12
BCLl2-like 15
chr13_+_83723255 0.08 ENSMUST00000199167.5
ENSMUST00000195904.5
myocyte enhancer factor 2C
chr12_+_76884182 0.08 ENSMUST00000041008.10
farnesyltransferase, CAAX box, beta
chr11_+_110956980 0.08 ENSMUST00000042970.3
potassium inwardly-rectifying channel, subfamily J, member 2
chr12_-_70160491 0.08 ENSMUST00000222237.2
ninein
chr2_+_172235820 0.07 ENSMUST00000109136.3
ENSMUST00000228775.2
Cas scaffolding protein family member 4
chr6_-_116050081 0.07 ENSMUST00000173548.3
transmembrane and coiled coil domains 1
chr7_-_45109075 0.07 ENSMUST00000210864.2
ferritin light polypeptide 1
chr3_+_20011251 0.07 ENSMUST00000108328.8
ceruloplasmin
chr8_+_11547506 0.07 ENSMUST00000177955.8
ENSMUST00000033901.11
ENSMUST00000178721.2
NAD(P)HX dehydratase
chr3_+_20011405 0.06 ENSMUST00000108325.9
ceruloplasmin
chr12_-_101785307 0.06 ENSMUST00000021603.9
fibulin 5
chr9_-_103107495 0.06 ENSMUST00000035158.16
transferrin
chr9_+_121211820 0.06 ENSMUST00000209995.2
trafficking protein, kinesin binding 1
chr15_-_76191301 0.06 ENSMUST00000171340.9
ENSMUST00000023222.13
ENSMUST00000164189.2
5-oxoprolinase (ATP-hydrolysing)
chr13_+_16186410 0.06 ENSMUST00000042603.14
inhibin beta-A
chr15_+_59520199 0.06 ENSMUST00000067543.8
tribbles pseudokinase 1
chr4_+_124635635 0.06 ENSMUST00000094782.10
ENSMUST00000153837.8
ENSMUST00000154229.2
inositol polyphosphate-5-phosphatase B
chr7_+_45084257 0.06 ENSMUST00000003964.17
glycogen synthase 1, muscle
chr1_-_131204422 0.06 ENSMUST00000159195.2
inhibitor of kappaB kinase epsilon
chr4_-_123458465 0.06 ENSMUST00000238731.2
microtubule-actin crosslinking factor 1
chr16_-_21814190 0.06 ENSMUST00000231766.2
ENSMUST00000074230.12
lipase, member H
chr1_-_164281344 0.06 ENSMUST00000193367.2
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr5_+_75312939 0.06 ENSMUST00000202681.4
ENSMUST00000000476.15
platelet derived growth factor receptor, alpha polypeptide
chr14_-_55950545 0.05 ENSMUST00000002389.9
ENSMUST00000226907.2
transglutaminase 1, K polypeptide
chr10_-_6930376 0.05 ENSMUST00000105617.8
interaction protein for cytohesin exchange factors 1
chr18_+_44237474 0.05 ENSMUST00000081271.7
serine peptidase inhibitor, Kazal type 12
chrX_+_94942639 0.05 ENSMUST00000082183.8
zinc finger CCCH-type containing 12B
chr14_+_22069877 0.05 ENSMUST00000161249.8
ENSMUST00000159777.8
ENSMUST00000162540.2
leucine rich melanocyte differentiation associated
chr2_+_119863909 0.05 ENSMUST00000126150.2
phospholipase A2, group IVB (cytosolic)
chr18_+_4994600 0.04 ENSMUST00000140448.8
supervillin

Network of associatons between targets according to the STRING database.

First level regulatory network of Cebpb

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.1 GO:0002588 positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002582) positive regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002588) detection of peptidoglycan(GO:0032499)
0.4 4.3 GO:0002227 innate immune response in mucosa(GO:0002227)
0.3 1.0 GO:0006428 isoleucyl-tRNA aminoacylation(GO:0006428)
0.3 1.2 GO:1901491 negative regulation of lymphangiogenesis(GO:1901491)
0.3 0.8 GO:0000448 cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000448)
0.2 2.9 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.2 0.6 GO:0046122 purine deoxyribonucleoside metabolic process(GO:0046122)
0.2 1.8 GO:0060763 mammary duct terminal end bud growth(GO:0060763)
0.2 0.8 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.2 0.5 GO:0070947 neutrophil mediated killing of fungus(GO:0070947)
0.2 0.6 GO:0006049 UDP-N-acetylglucosamine catabolic process(GO:0006049)
0.2 0.6 GO:0006507 GPI anchor release(GO:0006507) regulation of high-density lipoprotein particle clearance(GO:0010982)
0.1 0.6 GO:0050712 negative regulation of interleukin-1 alpha production(GO:0032690) negative regulation of interleukin-1 alpha secretion(GO:0050712)
0.1 0.4 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.1 0.6 GO:1903575 cornified envelope assembly(GO:1903575)
0.1 0.5 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.1 0.5 GO:1902109 negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109)
0.1 0.8 GO:0006207 'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
0.1 0.6 GO:0071898 regulation of estrogen receptor binding(GO:0071898) negative regulation of estrogen receptor binding(GO:0071899)
0.1 0.4 GO:0042851 L-alanine metabolic process(GO:0042851)
0.1 1.0 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.1 0.7 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.1 0.5 GO:0033140 negative regulation of peptidyl-serine phosphorylation of STAT protein(GO:0033140)
0.1 0.4 GO:0072738 response to diamide(GO:0072737) cellular response to diamide(GO:0072738)
0.1 0.3 GO:0050705 regulation of interleukin-1 alpha secretion(GO:0050705)
0.1 0.4 GO:0070859 positive regulation of bile acid biosynthetic process(GO:0070859) positive regulation of bile acid metabolic process(GO:1904253)
0.1 0.4 GO:0071947 protein deubiquitination involved in ubiquitin-dependent protein catabolic process(GO:0071947)
0.1 0.2 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.1 0.4 GO:0016259 selenocysteine metabolic process(GO:0016259)
0.1 0.3 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.1 0.3 GO:0010747 positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747)
0.1 0.2 GO:0021993 initiation of neural tube closure(GO:0021993)
0.1 0.3 GO:0060356 leucine import(GO:0060356)
0.1 0.2 GO:1901373 positive regulation of intracellular lipid transport(GO:0032379) positive regulation of intracellular sterol transport(GO:0032382) positive regulation of intracellular cholesterol transport(GO:0032385) lipid hydroperoxide transport(GO:1901373)
0.1 0.7 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.1 0.4 GO:0000821 regulation of arginine metabolic process(GO:0000821)
0.1 0.2 GO:0046136 positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
0.1 0.2 GO:0060671 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.1 0.3 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
0.0 0.9 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.1 GO:0061107 seminal vesicle development(GO:0061107)
0.0 0.3 GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
0.0 0.1 GO:0008588 release of cytoplasmic sequestered NF-kappaB(GO:0008588)
0.0 0.2 GO:0050917 sensory perception of sweet taste(GO:0050916) sensory perception of umami taste(GO:0050917)
0.0 0.1 GO:0052422 modulation by symbiont of host molecular function(GO:0052055) modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422)
0.0 0.3 GO:2001184 myoblast differentiation involved in skeletal muscle regeneration(GO:0014835) positive regulation of interleukin-12 secretion(GO:2001184)
0.0 0.3 GO:0070447 positive regulation of oligodendrocyte progenitor proliferation(GO:0070447)
0.0 0.5 GO:0006751 glutathione catabolic process(GO:0006751)
0.0 0.2 GO:0010968 regulation of microtubule nucleation(GO:0010968)
0.0 0.3 GO:0006561 proline biosynthetic process(GO:0006561)
0.0 0.7 GO:0007250 activation of NF-kappaB-inducing kinase activity(GO:0007250)
0.0 0.6 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.0 0.2 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376)
0.0 0.6 GO:0006337 nucleosome disassembly(GO:0006337)
0.0 0.6 GO:0030213 hyaluronan biosynthetic process(GO:0030213)
0.0 1.0 GO:1904376 negative regulation of protein localization to plasma membrane(GO:1903077) negative regulation of protein localization to cell periphery(GO:1904376)
0.0 0.1 GO:0031296 B cell costimulation(GO:0031296)
0.0 0.1 GO:0090076 relaxation of skeletal muscle(GO:0090076)
0.0 0.1 GO:2000016 negative regulation of determination of dorsal identity(GO:2000016)
0.0 0.4 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.1 GO:0070858 negative regulation of bile acid biosynthetic process(GO:0070858) negative regulation of bile acid metabolic process(GO:1904252)
0.0 0.1 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.0 0.3 GO:0045876 positive regulation of sister chromatid cohesion(GO:0045876)
0.0 0.2 GO:0038094 Fc-gamma receptor signaling pathway(GO:0038094)
0.0 0.5 GO:0006744 ubiquinone biosynthetic process(GO:0006744)
0.0 0.4 GO:0090051 regulation of skeletal muscle fiber development(GO:0048742) negative regulation of cell migration involved in sprouting angiogenesis(GO:0090051)
0.0 0.2 GO:0048251 elastic fiber assembly(GO:0048251)
0.0 0.2 GO:0002361 CD4-positive, CD25-positive, alpha-beta regulatory T cell differentiation(GO:0002361)
0.0 0.1 GO:0090222 centrosome-templated microtubule nucleation(GO:0090222)
0.0 0.2 GO:0006449 regulation of translational termination(GO:0006449)
0.0 0.1 GO:1903281 positive regulation of calcium:sodium antiporter activity(GO:1903281)
0.0 0.1 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.0 0.3 GO:1902231 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902231)
0.0 0.2 GO:0007016 cytoskeletal anchoring at plasma membrane(GO:0007016)
0.0 0.3 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.0 0.1 GO:0018343 protein farnesylation(GO:0018343)
0.0 0.5 GO:0046688 response to copper ion(GO:0046688)
0.0 0.6 GO:0071353 cellular response to interleukin-4(GO:0071353)
0.0 0.1 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 0.1 GO:0072275 metanephric glomerulus morphogenesis(GO:0072275) metanephric glomerulus vasculature morphogenesis(GO:0072276) metanephric glomerular capillary formation(GO:0072277)
0.0 0.3 GO:0019731 antibacterial humoral response(GO:0019731)
0.0 0.1 GO:0098957 anterograde axonal transport of mitochondrion(GO:0098957)
0.0 0.1 GO:0060279 positive regulation of ovulation(GO:0060279)
0.0 0.3 GO:0043552 positive regulation of phosphatidylinositol 3-kinase activity(GO:0043552)
0.0 0.4 GO:0010884 positive regulation of lipid storage(GO:0010884)
0.0 0.0 GO:0042560 10-formyltetrahydrofolate catabolic process(GO:0009258) folic acid-containing compound catabolic process(GO:0009397) pteridine-containing compound catabolic process(GO:0042560)
0.0 0.1 GO:0046477 glycosylceramide catabolic process(GO:0046477)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 2.9 GO:0043203 axon hillock(GO:0043203)
0.2 4.3 GO:0042581 specific granule(GO:0042581)
0.1 0.3 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.1 0.3 GO:0097169 AIM2 inflammasome complex(GO:0097169)
0.1 0.6 GO:0097255 R2TP complex(GO:0097255)
0.1 1.0 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.1 0.7 GO:0016272 prefoldin complex(GO:0016272)
0.1 0.8 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.4 GO:0031232 extrinsic component of external side of plasma membrane(GO:0031232)
0.0 0.3 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.0 1.3 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.4 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.0 0.1 GO:0036488 CHOP-C/EBP complex(GO:0036488)
0.0 0.2 GO:0071953 elastic fiber(GO:0071953)
0.0 0.3 GO:0042382 paraspeckles(GO:0042382)
0.0 0.5 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)
0.0 0.8 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.1 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.0 0.3 GO:0070531 BRCA1-A complex(GO:0070531)
0.0 0.4 GO:0030061 mitochondrial crista(GO:0030061)
0.0 0.1 GO:0043512 inhibin A complex(GO:0043512)
0.0 0.2 GO:0005640 nuclear outer membrane(GO:0005640)
0.0 0.4 GO:0001741 XY body(GO:0001741)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0004822 isoleucine-tRNA ligase activity(GO:0004822)
0.3 0.8 GO:0004087 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.2 0.6 GO:0004731 purine-nucleoside phosphorylase activity(GO:0004731)
0.2 0.8 GO:0004816 asparagine-tRNA ligase activity(GO:0004816)
0.2 2.1 GO:0042834 peptidoglycan binding(GO:0042834)
0.2 0.6 GO:0003827 alpha-1,3-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity(GO:0003827)
0.1 0.4 GO:0004756 selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
0.1 0.6 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.1 0.4 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.1 1.0 GO:0000099 sulfur amino acid transmembrane transporter activity(GO:0000099)
0.1 0.8 GO:0051731 polynucleotide 5'-hydroxyl-kinase activity(GO:0051731)
0.1 0.6 GO:0004966 galanin receptor activity(GO:0004966)
0.1 0.5 GO:0032450 maltose alpha-glucosidase activity(GO:0032450)
0.1 0.5 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.1 0.7 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.1 0.4 GO:0047635 L-alanine:2-oxoglutarate aminotransferase activity(GO:0004021) alanine-oxo-acid transaminase activity(GO:0047635)
0.1 0.2 GO:0004373 glycogen (starch) synthase activity(GO:0004373)
0.1 0.3 GO:0043532 angiostatin binding(GO:0043532)
0.1 0.5 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.1 0.6 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.1 1.1 GO:0005522 profilin binding(GO:0005522)
0.1 0.4 GO:0008384 IkappaB kinase activity(GO:0008384)
0.1 0.3 GO:0016649 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.1 0.4 GO:0001226 RNA polymerase II transcription corepressor binding(GO:0001226)
0.1 0.2 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.1 0.2 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.1 0.7 GO:0008061 chitin binding(GO:0008061)
0.1 0.2 GO:0050632 propanoyl-CoA C-acyltransferase activity(GO:0033814) propionyl-CoA C2-trimethyltridecanoyltransferase activity(GO:0050632) phosphatidylethanolamine transporter activity(GO:1904121)
0.1 0.3 GO:0004735 pyrroline-5-carboxylate reductase activity(GO:0004735)
0.1 0.8 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.1 0.3 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.0 0.3 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.0 0.2 GO:0031544 peptidyl-proline 3-dioxygenase activity(GO:0031544)
0.0 0.3 GO:0015091 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.0 0.1 GO:0052692 raffinose alpha-galactosidase activity(GO:0052692)
0.0 0.7 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 0.9 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.4 GO:0015217 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.0 0.2 GO:0046920 alpha-(1->3)-fucosyltransferase activity(GO:0046920)
0.0 0.4 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.4 GO:1990380 Lys48-specific deubiquitinase activity(GO:1990380)
0.0 0.6 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.3 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.1 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.0 3.8 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)
0.0 0.1 GO:0004945 angiotensin type II receptor activity(GO:0004945)
0.0 0.4 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)
0.0 0.9 GO:0043539 protein serine/threonine kinase activator activity(GO:0043539)
0.0 0.2 GO:0004630 phospholipase D activity(GO:0004630)
0.0 0.3 GO:0051525 NFAT protein binding(GO:0051525)
0.0 0.1 GO:0052658 inositol-1,4,5-trisphosphate 5-phosphatase activity(GO:0052658)
0.0 0.3 GO:0030274 LIM domain binding(GO:0030274)
0.0 0.1 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.0 0.7 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.0 1.2 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.5 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 1.8 GO:0030971 receptor tyrosine kinase binding(GO:0030971)
0.0 0.1 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.4 GO:0032183 SUMO binding(GO:0032183)
0.0 0.4 GO:0008483 transaminase activity(GO:0008483)
0.0 0.4 GO:0017127 cholesterol transporter activity(GO:0017127)
0.0 0.7 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.3 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.0 0.1 GO:0016812 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides(GO:0016812)
0.0 0.1 GO:0004720 protein-lysine 6-oxidase activity(GO:0004720)
0.0 0.2 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.3 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.6 GO:0004693 cyclin-dependent protein serine/threonine kinase activity(GO:0004693)
0.0 0.3 GO:0030676 Rac guanyl-nucleotide exchange factor activity(GO:0030676)
0.0 0.2 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.0 0.0 GO:0016155 formyltetrahydrofolate dehydrogenase activity(GO:0016155)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 3.4 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 1.4 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport
0.0 2.0 PID AMB2 NEUTROPHILS PATHWAY amb2 Integrin signaling
0.0 1.0 ST INTERLEUKIN 4 PATHWAY Interleukin 4 (IL-4) Pathway
0.0 1.0 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 1.0 PID UPA UPAR PATHWAY Urokinase-type plasminogen activator (uPA) and uPAR-mediated signaling
0.0 0.5 PID ANTHRAX PATHWAY Cellular roles of Anthrax toxin
0.0 2.2 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation
0.0 0.6 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.3 PID EPHA2 FWD PATHWAY EPHA2 forward signaling

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.1 0.9 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.1 4.2 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.1 2.1 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.1 1.8 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.1 1.8 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 1.4 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 1.7 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.6 REACTOME PURINE CATABOLISM Genes involved in Purine catabolism
0.0 0.2 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.5 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.3 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.3 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.3 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.4 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 0.7 REACTOME PREFOLDIN MEDIATED TRANSFER OF SUBSTRATE TO CCT TRIC Genes involved in Prefoldin mediated transfer of substrate to CCT/TriC
0.0 1.0 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.6 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.0 0.8 REACTOME GLYCOLYSIS Genes involved in Glycolysis
0.0 0.3 REACTOME ACTIVATION OF THE AP1 FAMILY OF TRANSCRIPTION FACTORS Genes involved in Activation of the AP-1 family of transcription factors
0.0 0.8 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import
0.0 0.1 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.6 REACTOME TRANSPORT TO THE GOLGI AND SUBSEQUENT MODIFICATION Genes involved in Transport to the Golgi and subsequent modification
0.0 0.5 REACTOME METAL ION SLC TRANSPORTERS Genes involved in Metal ion SLC transporters
0.0 0.4 REACTOME SEMA4D INDUCED CELL MIGRATION AND GROWTH CONE COLLAPSE Genes involved in Sema4D induced cell migration and growth-cone collapse
0.0 0.6 REACTOME G1 PHASE Genes involved in G1 Phase