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avrg: GFI1 WT vs 36n/n vs KD

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Results for Cebpd

Z-value: 0.93

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Transcription factors associated with Cebpd

Gene Symbol Gene ID Gene Info
Cebpd
ENSMUSG00000071637.6 CCAAT/enhancer binding protein (C/EBP), delta

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Cebpdmm39_v1_chr16_+_15705141_15705156-0.984.2e-03Click!

Activity profile of Cebpd motif

Sorted Z-values of Cebpd motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr11_-_75313412 0.96 ENSMUST00000138661.8
ENSMUST00000000769.14
Serpinf1
serine (or cysteine) peptidase inhibitor, clade F, member 1
chr11_-_75313350 0.93 ENSMUST00000125982.2
ENSMUST00000137103.8
Serpinf1
serine (or cysteine) peptidase inhibitor, clade F, member 1
chr14_+_67953547 0.68 ENSMUST00000078053.13
Kctd9
potassium channel tetramerisation domain containing 9
chr17_-_56428968 0.66 ENSMUST00000041357.9
Lrg1
leucine-rich alpha-2-glycoprotein 1
chr4_-_136626073 0.57 ENSMUST00000046285.6
C1qa
complement component 1, q subcomponent, alpha polypeptide
chr17_+_48653429 0.52 ENSMUST00000024791.15
Trem2
triggering receptor expressed on myeloid cells 2
chr17_+_87270504 0.49 ENSMUST00000024956.15
Rhoq
ras homolog family member Q
chr4_+_152123772 0.44 ENSMUST00000084116.13
ENSMUST00000103197.5
Nol9
nucleolar protein 9
chr17_+_48653493 0.43 ENSMUST00000113237.4
Trem2
triggering receptor expressed on myeloid cells 2
chr17_-_36343573 0.42 ENSMUST00000102678.5
H2-T23
histocompatibility 2, T region locus 23
chr17_+_37581103 0.39 ENSMUST00000038580.7
H2-M3
histocompatibility 2, M region locus 3
chr7_-_126873219 0.38 ENSMUST00000082428.6
Sephs2
selenophosphate synthetase 2
chr8_-_46664321 0.36 ENSMUST00000034049.5
Slc25a4
solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 4
chr7_-_46365108 0.32 ENSMUST00000006956.9
ENSMUST00000210913.2
Saa3
serum amyloid A 3
chr5_+_115417725 0.30 ENSMUST00000040421.11
Coq5
coenzyme Q5 methyltransferase
chr7_-_45480200 0.29 ENSMUST00000107723.9
ENSMUST00000131384.3
Grwd1
glutamate-rich WD repeat containing 1
chr5_-_100867520 0.29 ENSMUST00000112908.2
ENSMUST00000045617.15
Hpse
heparanase
chr4_+_63262775 0.28 ENSMUST00000030044.3
Orm1
orosomucoid 1
chr4_-_108690741 0.27 ENSMUST00000102740.8
ENSMUST00000102741.8
Btf3l4
basic transcription factor 3-like 4
chr11_+_106107752 0.26 ENSMUST00000021046.6
Ddx42
DEAD box helicase 42
chr2_-_3513783 0.26 ENSMUST00000124331.8
ENSMUST00000140494.2
ENSMUST00000027961.12
Gm45902
Hspa14
predicted gene 45902
heat shock protein 14
chr11_-_106107132 0.24 ENSMUST00000002043.10
Ccdc47
coiled-coil domain containing 47
chr6_-_11907392 0.23 ENSMUST00000204084.3
ENSMUST00000031637.8
ENSMUST00000204978.3
ENSMUST00000204714.2
Ndufa4
Ndufa4, mitochondrial complex associated
chr16_-_65359406 0.23 ENSMUST00000231259.2
Chmp2b
charged multivesicular body protein 2B
chr5_-_129856267 0.21 ENSMUST00000201394.4
Psph
phosphoserine phosphatase
chr11_-_72441054 0.21 ENSMUST00000021154.7
Spns3
spinster homolog 3
chrX_+_158086253 0.20 ENSMUST00000112491.2
Rps6ka3
ribosomal protein S6 kinase polypeptide 3
chr17_+_87270707 0.20 ENSMUST00000139344.2
Rhoq
ras homolog family member Q
chr19_+_55240357 0.19 ENSMUST00000225551.2
Acsl5
acyl-CoA synthetase long-chain family member 5
chr7_+_30463175 0.17 ENSMUST00000165887.8
ENSMUST00000085691.11
ENSMUST00000054427.13
ENSMUST00000085688.11
Dmkn
dermokine
chr14_+_22069709 0.17 ENSMUST00000075639.11
Lrmda
leucine rich melanocyte differentiation associated
chr6_-_3968365 0.15 ENSMUST00000031674.11
Tfpi2
tissue factor pathway inhibitor 2
chr14_+_67953584 0.15 ENSMUST00000145542.8
ENSMUST00000125212.2
Kctd9
potassium channel tetramerisation domain containing 9
chr9_-_103107460 0.15 ENSMUST00000165296.8
ENSMUST00000112645.8
Trf
transferrin
chr3_+_20011201 0.14 ENSMUST00000091309.12
ENSMUST00000108329.8
ENSMUST00000003714.13
Cp
ceruloplasmin
chr4_-_43558386 0.14 ENSMUST00000130353.2
Tln1
talin 1
chr2_-_129213050 0.13 ENSMUST00000028881.14
Il1b
interleukin 1 beta
chr11_-_86977576 0.11 ENSMUST00000020801.14
Smg8
smg-8 homolog, nonsense mediated mRNA decay factor (C. elegans)
chr5_-_147831610 0.11 ENSMUST00000118527.8
ENSMUST00000031655.4
ENSMUST00000138244.2
Slc46a3
solute carrier family 46, member 3
chr7_-_44181477 0.10 ENSMUST00000098483.9
ENSMUST00000035323.6
Spib
Spi-B transcription factor (Spi-1/PU.1 related)
chr2_+_172235820 0.09 ENSMUST00000109136.3
ENSMUST00000228775.2
Cass4
Cas scaffolding protein family member 4
chrX_-_133501874 0.09 ENSMUST00000033621.8
Gla
galactosidase, alpha
chr2_+_15531281 0.09 ENSMUST00000146205.3
Malrd1
MAM and LDL receptor class A domain containing 1
chr13_-_117161921 0.09 ENSMUST00000223949.2
Parp8
poly (ADP-ribose) polymerase family, member 8
chr3_+_66127330 0.07 ENSMUST00000029421.6
Ptx3
pentraxin related gene
chr6_-_87786736 0.07 ENSMUST00000032134.9
Rab43
RAB43, member RAS oncogene family
chr8_+_94763826 0.07 ENSMUST00000109556.9
ENSMUST00000093301.9
ENSMUST00000060632.8
Ogfod1
2-oxoglutarate and iron-dependent oxygenase domain containing 1
chr4_-_130253703 0.07 ENSMUST00000134159.3
Zcchc17
zinc finger, CCHC domain containing 17
chr13_-_117162041 0.06 ENSMUST00000022239.8
Parp8
poly (ADP-ribose) polymerase family, member 8
chr19_-_8796288 0.06 ENSMUST00000153281.2
Ttc9c
tetratricopeptide repeat domain 9C
chr10_-_6930376 0.06 ENSMUST00000105617.8
Ipcef1
interaction protein for cytohesin exchange factors 1
chr5_-_129856237 0.05 ENSMUST00000118268.9
Psph
phosphoserine phosphatase
chr18_+_44237474 0.04 ENSMUST00000081271.7
Spink12
serine peptidase inhibitor, Kazal type 12
chr7_-_45109075 0.04 ENSMUST00000210864.2
Ftl1
ferritin light polypeptide 1
chr9_-_103107495 0.04 ENSMUST00000035158.16
Trf
transferrin
chr1_-_164281344 0.04 ENSMUST00000193367.2
Atp1b1
ATPase, Na+/K+ transporting, beta 1 polypeptide
chr3_+_20011405 0.04 ENSMUST00000108325.9
Cp
ceruloplasmin
chrX_+_133501928 0.04 ENSMUST00000074950.11
ENSMUST00000113203.2
ENSMUST00000113202.8
ENSMUST00000050331.13
ENSMUST00000059297.6
Hnrnph2
heterogeneous nuclear ribonucleoprotein H2
chr3_+_20011251 0.04 ENSMUST00000108328.8
Cp
ceruloplasmin
chr8_+_10056654 0.03 ENSMUST00000033892.9
Tnfsf13b
tumor necrosis factor (ligand) superfamily, member 13b
chr18_+_44237577 0.03 ENSMUST00000239465.2
Spink12
serine peptidase inhibitor, Kazal type 12
chr19_-_8796677 0.03 ENSMUST00000096751.11
Ttc9c
tetratricopeptide repeat domain 9C
chr19_-_50667079 0.03 ENSMUST00000209413.2
ENSMUST00000072685.13
ENSMUST00000164039.9
Sorcs1
sortilin-related VPS10 domain containing receptor 1
chr5_+_114284585 0.03 ENSMUST00000102582.8
Acacb
acetyl-Coenzyme A carboxylase beta
chr18_-_52662728 0.02 ENSMUST00000025409.9
Lox
lysyl oxidase
chr2_-_88559941 0.02 ENSMUST00000099815.2
Olfr1197
olfactory receptor 1197
chr18_-_52662917 0.02 ENSMUST00000171470.8
Lox
lysyl oxidase
chr2_-_88844406 0.02 ENSMUST00000099800.2
Olfr1216
olfactory receptor 1216
chr2_-_110781268 0.02 ENSMUST00000099623.10
Ano3
anoctamin 3
chr7_+_26006594 0.02 ENSMUST00000098657.5
Cyp2a4
cytochrome P450, family 2, subfamily a, polypeptide 4
chr14_-_68771138 0.01 ENSMUST00000022640.8
Adam7
a disintegrin and metallopeptidase domain 7
chr7_+_13467422 0.01 ENSMUST00000086148.8
Sult2a2
sulfotransferase family 2A, dehydroepiandrosterone (DHEA)-preferring, member 2
chr5_+_8010445 0.01 ENSMUST00000115421.3
Steap4
STEAP family member 4
chr6_-_116050081 0.01 ENSMUST00000173548.3
Tmcc1
transmembrane and coiled coil domains 1
chr14_-_45715308 0.01 ENSMUST00000141424.2
Fermt2
fermitin family member 2
chr16_-_22847808 0.01 ENSMUST00000115349.9
Kng2
kininogen 2
chr1_-_106980033 0.01 ENSMUST00000112717.3
Serpinb3a
serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 3A
chr14_+_22069877 0.01 ENSMUST00000161249.8
ENSMUST00000159777.8
ENSMUST00000162540.2
Lrmda
leucine rich melanocyte differentiation associated
chr18_-_43925932 0.01 ENSMUST00000237926.2
ENSMUST00000096570.4
Gm94
predicted gene 94
chr8_+_10056631 0.01 ENSMUST00000207792.3
Tnfsf13b
tumor necrosis factor (ligand) superfamily, member 13b
chr1_-_107088844 0.01 ENSMUST00000086694.11
Serpinb3b
serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 3B
chr15_-_101759212 0.00 ENSMUST00000023790.5
Krt1
keratin 1
chr6_+_17463748 0.00 ENSMUST00000115443.8
Met
met proto-oncogene
chr1_+_164624200 0.00 ENSMUST00000027861.6
Dpt
dermatopontin
chr17_-_36679309 0.00 ENSMUST00000073546.5
H2-M10.3
histocompatibility 2, M region locus 10.3
chr2_+_14828903 0.00 ENSMUST00000193800.6
Cacnb2
calcium channel, voltage-dependent, beta 2 subunit
chr2_-_25360043 0.00 ENSMUST00000114251.8
Ptgds
prostaglandin D2 synthase (brain)
chr9_-_48516447 0.00 ENSMUST00000034808.12
ENSMUST00000119426.2
Nnmt
nicotinamide N-methyltransferase
chr2_-_25359752 0.00 ENSMUST00000114259.3
ENSMUST00000015234.13
Ptgds
prostaglandin D2 synthase (brain)

Network of associatons between targets according to the STRING database.

First level regulatory network of Cebpd

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0002588 positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002582) positive regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002588) detection of peptidoglycan(GO:0032499)
0.3 0.8 GO:0002476 antigen processing and presentation of endogenous peptide antigen via MHC class Ib(GO:0002476)
0.2 1.9 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.1 0.4 GO:0000448 cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000448)
0.1 0.3 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.1 0.4 GO:1902109 negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109)
0.1 0.4 GO:0016259 selenocysteine metabolic process(GO:0016259)
0.0 0.2 GO:1903575 cornified envelope assembly(GO:1903575)
0.0 0.1 GO:0046136 positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
0.0 0.2 GO:0010747 positive regulation of plasma membrane long-chain fatty acid transport(GO:0010747)
0.0 0.3 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.0 0.2 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376)
0.0 0.1 GO:0052203 modulation by symbiont of host molecular function(GO:0052055) modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422)
0.0 0.1 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.0 0.2 GO:0070447 positive regulation of oligodendrocyte progenitor proliferation(GO:0070447)
0.0 0.7 GO:1904376 negative regulation of protein localization to plasma membrane(GO:1903077) negative regulation of protein localization to cell periphery(GO:1904376)
0.0 0.7 GO:1903846 positive regulation of transforming growth factor beta receptor signaling pathway(GO:0030511) positive regulation of cellular response to transforming growth factor beta stimulus(GO:1903846)
0.0 0.2 GO:0006983 ER overload response(GO:0006983)
0.0 0.3 GO:0006337 nucleosome disassembly(GO:0006337)
0.0 0.1 GO:1904252 negative regulation of bile acid biosynthetic process(GO:0070858) negative regulation of bile acid metabolic process(GO:1904252)
0.0 0.3 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.0 0.0 GO:1903281 positive regulation of calcium:sodium antiporter activity(GO:1903281)
0.0 0.3 GO:0006744 ubiquinone biosynthetic process(GO:0006744)
0.0 0.2 GO:0039702 viral budding via host ESCRT complex(GO:0039702) regulation of mitotic spindle assembly(GO:1901673)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.9 GO:0043203 axon hillock(GO:0043203)
0.0 0.8 GO:0042611 MHC protein complex(GO:0042611)
0.0 0.2 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.2 GO:0097433 dense body(GO:0097433)
0.0 0.2 GO:0005751 mitochondrial respiratory chain complex IV(GO:0005751)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0016781 selenide, water dikinase activity(GO:0004756) phosphotransferase activity, paired acceptors(GO:0016781)
0.1 0.9 GO:0070891 lipoteichoic acid binding(GO:0070891)
0.1 0.4 GO:0051731 polynucleotide 5'-hydroxyl-kinase activity(GO:0051731)
0.0 0.3 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.0 0.7 GO:0005522 profilin binding(GO:0005522)
0.0 0.3 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.0 0.2 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.0 0.4 GO:0005347 ATP transmembrane transporter activity(GO:0005347) ADP transmembrane transporter activity(GO:0015217)
0.0 0.8 GO:0097602 cullin family protein binding(GO:0097602)
0.0 0.1 GO:0052692 raffinose alpha-galactosidase activity(GO:0052692)
0.0 0.3 GO:0045545 syndecan binding(GO:0045545)
0.0 0.2 GO:0015091 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.0 0.4 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.0 0.1 GO:0031544 peptidyl-proline 3-dioxygenase activity(GO:0031544)
0.0 0.3 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.2 GO:0016724 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.4 GO:0042605 peptide antigen binding(GO:0042605)
0.0 2.1 GO:0004867 serine-type endopeptidase inhibitor activity(GO:0004867)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 PID INSULIN GLUCOSE PATHWAY Insulin-mediated glucose transport

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.9 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.3 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation