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avrg: GFI1 WT vs 36n/n vs KD

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Results for Dmc1

Z-value: 0.50

Motif logo

Transcription factors associated with Dmc1

Gene Symbol Gene ID Gene Info
ENSMUSG00000022429.12 DNA meiotic recombinase 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Dmc1mm39_v1_chr15_-_79489286_79489315-0.108.7e-01Click!

Activity profile of Dmc1 motif

Sorted Z-values of Dmc1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr7_-_107696793 0.29 ENSMUST00000217304.2
olfactory receptor 482
chr5_-_115257336 0.26 ENSMUST00000031524.11
acyl-Coenzyme A dehydrogenase, short chain
chr17_+_35643818 0.25 ENSMUST00000174699.8
histocompatibility 2, Q region locus 6
chr6_-_7692855 0.25 ENSMUST00000115542.8
ENSMUST00000148349.2
asparagine synthetase
chr11_-_29497819 0.24 ENSMUST00000102844.4
ribosomal protein S27A
chr17_+_35643853 0.24 ENSMUST00000113879.4
histocompatibility 2, Q region locus 6
chr4_+_102617332 0.23 ENSMUST00000066824.14
SH3-domain GRB2-like (endophilin) interacting protein 1
chr6_-_68713748 0.23 ENSMUST00000183936.2
ENSMUST00000196863.2
immunoglobulin kappa chain variable 19-93
chr10_+_128745214 0.22 ENSMUST00000220308.2
CD63 antigen
chr11_+_3280401 0.21 ENSMUST00000045153.11
phosphoinositide-3-kinase interacting protein 1
chrX_+_133657312 0.21 ENSMUST00000081834.10
ENSMUST00000086880.11
ENSMUST00000086884.5
armadillo repeat containing, X-linked 3
chr2_-_91274967 0.19 ENSMUST00000064652.14
ENSMUST00000102594.11
ENSMUST00000094835.9
RIKEN cDNA 1110051M20 gene
chr3_+_108164242 0.19 ENSMUST00000090569.10
proteasome subunit alpha 5
chr2_+_103800459 0.19 ENSMUST00000111143.8
ENSMUST00000138815.2
LIM domain only 2
chr14_-_73613385 0.19 ENSMUST00000227454.2
integral membrane protein 2B
chr4_-_42856771 0.18 ENSMUST00000107981.2
predicted gene 12394
chr6_+_17749169 0.18 ENSMUST00000053148.14
ENSMUST00000115417.4
suppression of tumorigenicity 7
chr4_-_107928567 0.18 ENSMUST00000106701.2
sterol carrier protein 2, liver
chr15_+_84208915 0.18 ENSMUST00000023074.9
parvin, gamma
chr6_-_126916487 0.17 ENSMUST00000144954.5
ENSMUST00000112220.8
ENSMUST00000112221.8
RAD51 associated protein 1
chr13_+_33187205 0.17 ENSMUST00000063191.14
serine (or cysteine) peptidase inhibitor, clade B, member 9
chr5_+_149202157 0.17 ENSMUST00000200806.4
arachidonate 5-lipoxygenase activating protein
chr2_+_84810802 0.16 ENSMUST00000028467.6
proteoglycan 2, bone marrow
chr4_+_138926577 0.16 ENSMUST00000145368.8
capping protein (actin filament) muscle Z-line, beta
chr6_-_7693184 0.16 ENSMUST00000031766.12
asparagine synthetase
chr7_-_125090540 0.16 ENSMUST00000138616.3
NSE1 homolog, SMC5-SMC6 complex component
chr12_-_85420684 0.16 ENSMUST00000222585.2
transmembrane p24 trafficking protein 10
chrX_-_72502595 0.16 ENSMUST00000033737.15
ENSMUST00000077243.5
HAUS augmin-like complex, subunit 7
chr16_-_56984137 0.15 ENSMUST00000231733.2
nitrilase family, member 2
chr2_+_151385797 0.15 ENSMUST00000142271.2
FK506 binding protein 1a
chr14_-_56026266 0.15 ENSMUST00000168716.8
ENSMUST00000178399.3
ENSMUST00000022830.14
receptor-interacting serine-threonine kinase 3
chr1_-_75101826 0.15 ENSMUST00000152855.3
non-homologous end joining factor 1
chrX_+_134786600 0.14 ENSMUST00000180025.8
ENSMUST00000148374.8
ENSMUST00000068755.14
basic helix-loop-helix domain containing, class B9
chr17_+_34062059 0.14 ENSMUST00000002379.15
CD320 antigen
chr7_-_79765042 0.14 ENSMUST00000206714.2
ENSMUST00000107384.10
isocitrate dehydrogenase 2 (NADP+), mitochondrial
chr8_-_57003828 0.14 ENSMUST00000134162.8
ENSMUST00000140107.8
ENSMUST00000040330.15
ENSMUST00000135337.8
centrosomal protein 44
chr5_-_92496730 0.14 ENSMUST00000038816.13
ENSMUST00000118006.3
chemokine (C-X-C motif) ligand 10
chr11_-_48836975 0.14 ENSMUST00000104958.2
protease (prosome, macropain) activator subunit 2B
chr17_-_35827676 0.14 ENSMUST00000160885.2
ENSMUST00000159009.2
ENSMUST00000161012.8
transcription factor 19
chr11_+_3280771 0.13 ENSMUST00000136536.8
ENSMUST00000093399.11
phosphoinositide-3-kinase interacting protein 1
chr3_+_100829798 0.13 ENSMUST00000106980.9
tripartite motif-containing 45
chr6_+_48653047 0.13 ENSMUST00000054050.5
GTPase, IMAP family member 9
chr15_-_60696790 0.13 ENSMUST00000100635.5
LRAT domain containing 1
chr8_-_85620537 0.13 ENSMUST00000003907.14
ENSMUST00000109745.8
ENSMUST00000142748.2
glutaryl-Coenzyme A dehydrogenase
chr6_-_115652831 0.13 ENSMUST00000112949.8
v-raf-leukemia viral oncogene 1
chr1_-_192946359 0.13 ENSMUST00000161737.8
hydroxysteroid 11-beta dehydrogenase 1
chr12_+_100076407 0.13 ENSMUST00000021595.10
protease (prosome, macropain) 26S subunit, ATPase 1
chr4_-_116664729 0.13 ENSMUST00000106455.8
ENSMUST00000030451.10
target of EGR1, member 1 (nuclear)
chr9_+_110867807 0.13 ENSMUST00000197575.2
lactotransferrin
chr1_-_52271455 0.12 ENSMUST00000114512.8
glutaminase
chr3_+_100829750 0.12 ENSMUST00000037409.13
tripartite motif-containing 45
chr19_-_4675352 0.12 ENSMUST00000224707.2
ENSMUST00000237059.2
Ras converting CAAX endopeptidase 1
chr5_+_149201577 0.12 ENSMUST00000071130.5
arachidonate 5-lipoxygenase activating protein
chr13_+_62277700 0.12 ENSMUST00000221772.2
ENSMUST00000099449.4
zinc finger protein 808
chr1_-_184578057 0.12 ENSMUST00000068725.10
mitochondrial amidoxime reducing component 2
chr3_+_14706781 0.12 ENSMUST00000029071.9
carbonic anhydrase 13
chr12_-_79239022 0.12 ENSMUST00000161204.8
retinol dehydrogenase 11
chr11_-_6217718 0.12 ENSMUST00000004507.11
ENSMUST00000151446.2
DEAD box helicase 56
chr1_+_52026296 0.12 ENSMUST00000168302.8
signal transducer and activator of transcription 4
chr2_+_103799873 0.12 ENSMUST00000123437.8
LIM domain only 2
chr11_-_116164928 0.12 ENSMUST00000106425.4
signal recognition particle 68
chr1_-_156501860 0.12 ENSMUST00000188964.7
ENSMUST00000190607.2
ENSMUST00000079625.11
torsin family 3, member A
chr19_+_8931187 0.12 ENSMUST00000096239.7
terminal uridylyl transferase 1, U6 snRNA-specific
chr4_-_116508842 0.12 ENSMUST00000030455.15
aldo-keto reductase family 1, member A1 (aldehyde reductase)
chr10_-_81201642 0.12 ENSMUST00000020456.5
RIKEN cDNA 4930404N11 gene
chr6_+_82923876 0.11 ENSMUST00000113980.4
meiosis 1 associated protein
chr18_+_32970363 0.11 ENSMUST00000166214.9
WD repeat domain 36
chr17_-_25104874 0.11 ENSMUST00000234597.2
nucleotide binding protein 2
chr2_-_126342551 0.11 ENSMUST00000129187.2
ATPase, class I, type 8B, member 4
chr10_-_75673175 0.11 ENSMUST00000220440.2
glutathione S-transferase, theta 2
chr11_+_115455260 0.11 ENSMUST00000021085.11
nucleoporin 85
chr6_-_128414616 0.11 ENSMUST00000151796.3
FK506 binding protein 4
chr17_-_65901946 0.11 ENSMUST00000232686.2
vesicle-associated membrane protein, associated protein A
chr17_-_80514725 0.11 ENSMUST00000234696.2
ENSMUST00000235069.2
ENSMUST00000063417.11
serine and arginine-rich splicing factor 7
chr6_+_126916956 0.11 ENSMUST00000201617.2
DNA segment, Chr 6, Wayne State University 163, expressed
chr17_-_28736483 0.11 ENSMUST00000114792.8
ENSMUST00000177939.8
FK506 binding protein 5
chr14_-_78866714 0.11 ENSMUST00000228362.2
ENSMUST00000227767.2
diacylglycerol kinase, eta
chr18_+_77032080 0.11 ENSMUST00000026485.15
ENSMUST00000150990.9
ENSMUST00000148955.3
haloacid dehalogenase-like hydrolase domain containing 2
chr17_+_37581103 0.11 ENSMUST00000038580.7
histocompatibility 2, M region locus 3
chr6_+_34361153 0.11 ENSMUST00000038383.14
ENSMUST00000115051.8
aldo-keto reductase family 1, member B10 (aldose reductase)
chr18_+_32970278 0.11 ENSMUST00000053663.11
WD repeat domain 36
chrX_-_149223883 0.11 ENSMUST00000163233.2
transmembrane protein 29
chr7_+_46496929 0.10 ENSMUST00000132157.2
ENSMUST00000210631.2
lactate dehydrogenase A
chr19_-_4675300 0.10 ENSMUST00000225264.2
ENSMUST00000237022.2
ENSMUST00000224675.3
Ras converting CAAX endopeptidase 1
chr1_-_106687457 0.10 ENSMUST00000010049.6
3-ketodihydrosphingosine reductase
chr19_+_36325683 0.10 ENSMUST00000225920.2
polycomb group ring finger 5
chr9_+_113641615 0.10 ENSMUST00000111838.10
ENSMUST00000166734.10
ENSMUST00000214522.2
ENSMUST00000163895.3
CLIP associating protein 2
chr12_+_103354915 0.10 ENSMUST00000101094.9
ENSMUST00000021620.13
OTU domain, ubiquitin aldehyde binding 2
chr1_+_16735401 0.10 ENSMUST00000177501.2
ENSMUST00000065373.6
transmembrane protein 70
chr4_-_117039809 0.10 ENSMUST00000065896.9
kinesin family member 2C
chr15_-_38518406 0.10 ENSMUST00000151319.8
antizyme inhibitor 1
chr9_-_37568570 0.10 ENSMUST00000117654.3
transforming growth factor beta regulated gene 1
chr7_+_90091937 0.10 ENSMUST00000061767.5
CREB/ATF bZIP transcription factor
chr8_-_123939480 0.10 ENSMUST00000000759.9
charged multivesicular body protein 1A
chr19_-_3956991 0.10 ENSMUST00000126070.9
ENSMUST00000001801.11
T cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 protein A3
chr15_+_82984402 0.10 ENSMUST00000078218.11
serine hydrolase-like
chr7_+_131162338 0.10 ENSMUST00000208571.2
BUB3 mitotic checkpoint protein
chr9_-_21421458 0.10 ENSMUST00000213167.2
ENSMUST00000034698.9
transmembrane p24 trafficking protein 1
chr15_+_82984481 0.10 ENSMUST00000167389.9
ENSMUST00000166427.8
serine hydrolase-like
chr11_-_58059293 0.10 ENSMUST00000172035.8
ENSMUST00000035604.13
ENSMUST00000102711.9
gem nuclear organelle associated protein 5
chr16_-_96244794 0.09 ENSMUST00000113773.2
ENSMUST00000000161.14
integrin beta 2-like
chr14_-_14389372 0.09 ENSMUST00000023924.4
ribonuclease P 14 subunit
chr7_-_24423715 0.09 ENSMUST00000081657.6
Ly6/PLAUR domain containing 11
chr18_-_46874611 0.09 ENSMUST00000035648.6
autophagy related 12
chr3_-_97517472 0.09 ENSMUST00000029730.5
chromodomain helicase DNA binding protein 1-like
chr16_+_48692976 0.09 ENSMUST00000065666.6
resistin like gamma
chr16_-_16950241 0.09 ENSMUST00000023453.10
stromal cell-derived factor 2-like 1
chr6_+_137731526 0.09 ENSMUST00000203216.3
ENSMUST00000087675.9
ENSMUST00000203693.3
deoxyribose-phosphate aldolase (putative)
chr11_+_85202990 0.09 ENSMUST00000127717.2
protein phosphatase 1D magnesium-dependent, delta isoform
chr7_+_126575781 0.09 ENSMUST00000206450.2
ENSMUST00000205830.2
CDP-diacylglycerol--inositol 3-phosphatidyltransferase (phosphatidylinositol synthase)
chr19_-_38031774 0.09 ENSMUST00000226068.2
myoferlin
chr5_+_115417725 0.09 ENSMUST00000040421.11
coenzyme Q5 methyltransferase
chr2_-_25436884 0.09 ENSMUST00000114234.2
TNF receptor-associated factor 2
chr6_-_125208738 0.09 ENSMUST00000043422.8
TAP binding protein-like
chr7_+_65343156 0.09 ENSMUST00000032726.14
ENSMUST00000107495.5
ENSMUST00000143508.3
ENSMUST00000129166.3
ENSMUST00000206517.2
ENSMUST00000206837.2
ENSMUST00000206628.2
ENSMUST00000206361.2
TM2 domain containing 3
chr17_+_25517363 0.09 ENSMUST00000037453.4
protease, serine 34
chr7_-_117728790 0.09 ENSMUST00000206491.2
ADP-ribosylation factor-like 6 interacting protein 1
chr2_-_66086919 0.09 ENSMUST00000125446.3
ENSMUST00000102718.10
tetratricopeptide repeat domain 21B
chr6_-_129449739 0.09 ENSMUST00000112076.9
ENSMUST00000184581.3
C-type lectin domain family 7, member a
chr11_+_51858476 0.09 ENSMUST00000102763.5
CDKN2A interacting protein N-terminal like
chr9_+_73009680 0.09 ENSMUST00000034737.13
ENSMUST00000173734.9
ENSMUST00000167514.2
ENSMUST00000174203.3
KH domain containing 3, subcortical maternal complex member
predicted gene 20509
chr19_-_24938909 0.09 ENSMUST00000025815.10
COBW domain containing 1
chr16_-_87237438 0.09 ENSMUST00000039101.12
RWD domain containing 2B
chr13_-_62771948 0.08 ENSMUST00000223338.2
ENSMUST00000201563.4
RIKEN cDNA 6720489N17 gene
chr15_+_79784365 0.08 ENSMUST00000230135.2
apolipoprotein B mRNA editing enzyme, catalytic polypeptide 3
chr1_+_85992341 0.08 ENSMUST00000027432.9
proteasome (prosome, macropain) 26S subunit, non-ATPase, 1
chr2_-_26917921 0.08 ENSMUST00000102890.11
ENSMUST00000153388.2
ENSMUST00000045702.6
solute carrier family 2 (facilitated glucose transporter), member 6
chr7_-_143294051 0.08 ENSMUST00000119499.8
oxysterol binding protein-like 5
chr19_-_45548942 0.08 ENSMUST00000026239.7
polymerase (DNA directed), lambda
chrX_+_69429475 0.08 ENSMUST00000053981.6
endothelium and lymphocyte associated ASCH domain 1
chr2_+_35512023 0.08 ENSMUST00000091010.12
disabled 2 interacting protein
chr2_-_86109346 0.08 ENSMUST00000217294.2
ENSMUST00000217245.2
ENSMUST00000216432.2
olfactory receptor 1051
chr10_+_81193325 0.08 ENSMUST00000044844.9
major facilitator superfamily domain containing 12
chr1_-_194813843 0.08 ENSMUST00000075451.12
ENSMUST00000191775.2
complement component (3b/4b) receptor 1-like
chr3_+_96537484 0.08 ENSMUST00000200647.2
RNA binding motif protein 8a
chr7_-_46558754 0.08 ENSMUST00000209538.2
tumor susceptibility gene 101
chr13_-_62530965 0.08 ENSMUST00000202194.2
ENSMUST00000187656.7
predicted gene 3604
chr2_+_83554741 0.08 ENSMUST00000028499.11
integrin alpha V
chr8_+_124204598 0.08 ENSMUST00000001520.13
AFG3-like AAA ATPase 1
chr11_-_4799345 0.08 ENSMUST00000053079.13
ENSMUST00000109910.9
neurofibromin 2
chr7_-_30325514 0.08 ENSMUST00000208838.2
cytochrome c oxidase, subunit 6B1
chr13_+_30320446 0.08 ENSMUST00000047311.16
membrane bound O-acyltransferase domain containing 1
chr17_-_66756710 0.08 ENSMUST00000086693.12
ENSMUST00000097291.10
microtubule crosslinking factor 1
chr12_+_59060162 0.08 ENSMUST00000021379.8
gem nuclear organelle associated protein 2
chr9_+_104930438 0.08 ENSMUST00000149243.8
ENSMUST00000035177.15
ENSMUST00000214036.2
mitochondrial ribosomal protein L3
chr9_+_21504018 0.08 ENSMUST00000062125.11
translocase of inner mitochondrial membrane 29
chr4_+_130001349 0.08 ENSMUST00000030563.6
penta-EF hand domain containing 1
chr2_-_119617985 0.08 ENSMUST00000110793.8
ENSMUST00000099529.9
ENSMUST00000048493.12
RNA polymerase II associated protein 1
chr2_-_152857239 0.08 ENSMUST00000028972.9
p53 and DNA damage regulated 1
chr1_-_75118436 0.08 ENSMUST00000189403.7
cyclin Pas1/PHO80 domain containing 1
chr17_-_31731222 0.08 ENSMUST00000236665.2
WD repeat domain 4
chr12_+_55445560 0.07 ENSMUST00000021412.9
proteasome subunit alpha 6
chr16_-_10360893 0.07 ENSMUST00000184863.8
ENSMUST00000038281.6
dexamethasone-induced transcript
chr12_+_84332006 0.07 ENSMUST00000123614.8
ENSMUST00000147363.8
ENSMUST00000135001.8
ENSMUST00000146377.8
prostaglandin reductase 2
chrX_+_105059305 0.07 ENSMUST00000033582.5
cytochrome c oxidase subunit 7B
chr6_+_29272625 0.07 ENSMUST00000054445.9
hypoxia inducible lipid droplet associated
chr8_-_85807308 0.07 ENSMUST00000093357.12
WD repeat domain containing 83
chr10_+_61516078 0.07 ENSMUST00000220372.2
ENSMUST00000020285.10
ENSMUST00000219506.2
ENSMUST00000218474.2
secretion associated Ras related GTPase 1A
chr10_-_17898977 0.07 ENSMUST00000020002.9
ABRA C-terminal like
chr7_-_4066125 0.07 ENSMUST00000108600.9
ENSMUST00000205296.2
leukocyte-associated Ig-like receptor 1
chr7_-_27374017 0.07 ENSMUST00000036453.14
ENSMUST00000108341.2
mitogen-activated protein kinase kinase kinase 10
chr7_-_23998735 0.07 ENSMUST00000145131.8
zinc finger protein 61
chr14_+_21881794 0.07 ENSMUST00000152562.8
voltage-dependent anion channel 2
chr7_-_4066194 0.07 ENSMUST00000086400.13
leukocyte-associated Ig-like receptor 1
chr5_-_104169785 0.07 ENSMUST00000031251.16
hydroxysteroid (17-beta) dehydrogenase 11
chr15_-_38518458 0.07 ENSMUST00000127848.2
antizyme inhibitor 1
chr2_+_176115387 0.07 ENSMUST00000108995.9
ENSMUST00000127687.8
zinc finger protein 968, pseudogene
chr7_+_126575752 0.07 ENSMUST00000206346.2
CDP-diacylglycerol--inositol 3-phosphatidyltransferase (phosphatidylinositol synthase)
chr16_-_65359406 0.07 ENSMUST00000231259.2
charged multivesicular body protein 2B
chr5_+_45650821 0.07 ENSMUST00000198534.2
leucine aminopeptidase 3
chr4_-_11254253 0.07 ENSMUST00000044616.10
ENSMUST00000108319.9
ENSMUST00000108318.3
integrator complex subunit 8
chr4_+_11558905 0.07 ENSMUST00000095145.12
ENSMUST00000108306.9
ENSMUST00000070755.13
RAD54 homolog B (S. cerevisiae)
chr15_-_103123711 0.07 ENSMUST00000122182.2
ENSMUST00000108813.10
ENSMUST00000127191.2
chromobox 5
chr1_+_170846482 0.07 ENSMUST00000078825.5
Fc receptor, IgG, low affinity IV
chr15_-_75781138 0.07 ENSMUST00000145764.2
ENSMUST00000116440.9
ENSMUST00000151066.8
eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)
chr8_-_26505605 0.07 ENSMUST00000016138.11
farnesyltransferase, CAAX box, alpha
chr9_-_56151334 0.07 ENSMUST00000188142.7
pseudopodium-enriched atypical kinase 1
chr4_-_49521036 0.07 ENSMUST00000057829.4
mitochondrial ribosomal protein L50
chr2_+_173579285 0.07 ENSMUST00000067530.6
vesicle-associated membrane protein, associated protein B and C
chr1_-_58735106 0.07 ENSMUST00000055313.14
ENSMUST00000188772.7
flagellum associated containing coiled-coil domains 1
chr9_-_99450948 0.07 ENSMUST00000035043.12
armadillo repeat containing 8
chr7_-_90106375 0.07 ENSMUST00000032844.7
transmembrane protein 126A
chr18_-_35795233 0.06 ENSMUST00000025209.12
ENSMUST00000096573.4
spermatogenesis associated 24
chr1_-_75118335 0.06 ENSMUST00000190679.7
cyclin Pas1/PHO80 domain containing 1
chr3_+_135531548 0.06 ENSMUST00000167390.8
solute carrier family 39 (metal ion transporter), member 8
chr4_-_128512401 0.06 ENSMUST00000074829.4
toll-like receptor 12
chr5_-_107745443 0.06 ENSMUST00000100949.10
ENSMUST00000078021.13
glomulin, FKBP associated protein
chr4_-_117539431 0.06 ENSMUST00000102687.4
DNA methyltransferase 1-associated protein 1
chr17_+_26895379 0.06 ENSMUST00000236299.2
ENSMUST00000167352.2
ATPase, H+ transporting, lysosomal V0 subunit E
chr8_+_46984016 0.06 ENSMUST00000152423.2
acyl-CoA synthetase long-chain family member 1
chr12_+_86994117 0.06 ENSMUST00000187814.7
ENSMUST00000038369.11
CLOCK interacting protein, circadian
chr4_-_133615075 0.06 ENSMUST00000003741.16
ENSMUST00000105894.11
ribosomal protein S6 kinase polypeptide 1
chr11_+_6511133 0.06 ENSMUST00000160633.8
ENSMUST00000109721.3
cerebral cavernous malformation 2
chr1_-_72323464 0.06 ENSMUST00000027381.13
peroxisomal trans-2-enoyl-CoA reductase
chr5_-_115622356 0.06 ENSMUST00000112067.8
sirtuin 4
chr11_-_72106418 0.06 ENSMUST00000021157.9
mediator complex subunit 31
chr11_+_114566257 0.06 ENSMUST00000045779.6
tweety family member 2
chr5_+_122347792 0.06 ENSMUST00000072602.14
hydrogen voltage-gated channel 1
chr1_-_120197979 0.06 ENSMUST00000112639.8
STEAP family member 3
chr6_-_82629835 0.06 ENSMUST00000160281.8
ENSMUST00000095786.6
polymerase (DNA-directed), epsilon 4 (p12 subunit)

Network of associatons between targets according to the STRING database.

First level regulatory network of Dmc1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0006529 asparagine biosynthetic process(GO:0006529)
0.1 0.3 GO:0019626 short-chain fatty acid catabolic process(GO:0019626)
0.1 0.2 GO:0071586 CAAX-box protein processing(GO:0071586) CAAX-box protein maturation(GO:0080120)
0.1 0.2 GO:0002215 defense response to nematode(GO:0002215)
0.0 0.2 GO:1902269 positive regulation of polyamine transmembrane transport(GO:1902269)
0.0 0.3 GO:0002540 leukotriene production involved in inflammatory response(GO:0002540)
0.0 0.1 GO:1904464 regulation of matrix metallopeptidase secretion(GO:1904464) matrix metallopeptidase secretion(GO:1990773)
0.0 0.3 GO:2000680 regulation of rubidium ion transport(GO:2000680)
0.0 0.2 GO:0032385 positive regulation of intracellular lipid transport(GO:0032379) positive regulation of intracellular sterol transport(GO:0032382) positive regulation of intracellular cholesterol transport(GO:0032385) lipid hydroperoxide transport(GO:1901373)
0.0 0.5 GO:0043553 negative regulation of phosphatidylinositol 3-kinase activity(GO:0043553)
0.0 0.1 GO:0046949 fatty-acyl-CoA biosynthetic process(GO:0046949)
0.0 0.1 GO:0071550 death-inducing signaling complex assembly(GO:0071550)
0.0 0.1 GO:0006713 glucocorticoid catabolic process(GO:0006713)
0.0 0.0 GO:0090265 immune complex clearance by monocytes and macrophages(GO:0002436) regulation of immune complex clearance by monocytes and macrophages(GO:0090264) positive regulation of immune complex clearance by monocytes and macrophages(GO:0090265)
0.0 0.1 GO:0016062 adaptation of rhodopsin mediated signaling(GO:0016062) light adaption(GO:0036367)
0.0 0.2 GO:0035964 COPI-coated vesicle budding(GO:0035964)
0.0 0.1 GO:2000449 regulation of CD8-positive, alpha-beta T cell extravasation(GO:2000449)
0.0 0.1 GO:0002476 antigen processing and presentation of endogenous peptide antigen via MHC class Ib(GO:0002476)
0.0 0.1 GO:1901740 negative regulation of myoblast fusion(GO:1901740)
0.0 0.2 GO:0046341 CDP-diacylglycerol metabolic process(GO:0046341)
0.0 0.1 GO:0032066 nucleolus to nucleoplasm transport(GO:0032066)
0.0 0.1 GO:1903173 phytol metabolic process(GO:0033306) fatty alcohol metabolic process(GO:1903173)
0.0 0.1 GO:0045014 carbon catabolite repression of transcription(GO:0045013) negative regulation of transcription by glucose(GO:0045014)
0.0 0.1 GO:1900229 biofilm formation(GO:0042710) single-species biofilm formation(GO:0044010) single-species biofilm formation in or on host organism(GO:0044407) membrane disruption in other organism(GO:0051673) regulation of single-species biofilm formation(GO:1900190) negative regulation of single-species biofilm formation(GO:1900191) regulation of single-species biofilm formation in or on host organism(GO:1900228) negative regulation of single-species biofilm formation in or on host organism(GO:1900229)
0.0 0.2 GO:0006528 asparagine metabolic process(GO:0006528)
0.0 0.1 GO:0002589 regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590)
0.0 0.2 GO:0042270 protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.0 0.1 GO:0031296 B cell costimulation(GO:0031296)
0.0 0.1 GO:0002036 regulation of L-glutamate transport(GO:0002036)
0.0 0.1 GO:0033615 mitochondrial proton-transporting ATP synthase complex assembly(GO:0033615)
0.0 0.1 GO:1902527 positive regulation of protein monoubiquitination(GO:1902527)
0.0 0.2 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.0 0.1 GO:0019853 L-ascorbic acid biosynthetic process(GO:0019853)
0.0 0.1 GO:0002408 myeloid dendritic cell chemotaxis(GO:0002408)
0.0 0.1 GO:1903719 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265) regulation of I-kappaB phosphorylation(GO:1903719) positive regulation of I-kappaB phosphorylation(GO:1903721)
0.0 0.1 GO:0006543 glutamine catabolic process(GO:0006543)
0.0 0.1 GO:2000397 regulation of ubiquitin-dependent endocytosis(GO:2000395) positive regulation of ubiquitin-dependent endocytosis(GO:2000397)
0.0 0.1 GO:0046203 spermidine catabolic process(GO:0046203)
0.0 0.1 GO:0035425 autocrine signaling(GO:0035425)
0.0 0.1 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.0 0.1 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.0 0.1 GO:1901301 regulation of cargo loading into COPII-coated vesicle(GO:1901301)
0.0 0.1 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.0 0.3 GO:0097067 cellular response to thyroid hormone stimulus(GO:0097067)
0.0 0.2 GO:2000507 positive regulation of energy homeostasis(GO:2000507)
0.0 0.1 GO:0006710 androgen catabolic process(GO:0006710)
0.0 0.2 GO:0044829 positive regulation by host of viral genome replication(GO:0044829)
0.0 0.1 GO:1903679 regulation of cap-independent translational initiation(GO:1903677) positive regulation of cap-independent translational initiation(GO:1903679) regulation of cytoplasmic translational initiation(GO:1904688) positive regulation of cytoplasmic translational initiation(GO:1904690)
0.0 0.2 GO:0070574 cadmium ion transport(GO:0015691) cadmium ion transmembrane transport(GO:0070574)
0.0 0.1 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.0 0.1 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.0 0.1 GO:0007060 male meiosis chromosome segregation(GO:0007060)
0.0 0.0 GO:0090149 mitochondrial membrane fission(GO:0090149) regulation of peroxisome organization(GO:1900063)
0.0 0.1 GO:0034982 mitochondrial protein processing(GO:0034982)
0.0 0.0 GO:0071211 protein targeting to vacuole involved in autophagy(GO:0071211)
0.0 0.1 GO:0019287 isopentenyl diphosphate biosynthetic process, mevalonate pathway(GO:0019287)
0.0 0.0 GO:0002654 positive regulation of tolerance induction dependent upon immune response(GO:0002654) regulation of peripheral tolerance induction(GO:0002658) positive regulation of peripheral tolerance induction(GO:0002660) regulation of peripheral T cell tolerance induction(GO:0002849) positive regulation of peripheral T cell tolerance induction(GO:0002851)
0.0 0.1 GO:0006287 base-excision repair, gap-filling(GO:0006287)
0.0 0.0 GO:0032077 positive regulation of deoxyribonuclease activity(GO:0032077) positive regulation of endodeoxyribonuclease activity(GO:0032079)
0.0 0.1 GO:0018343 protein farnesylation(GO:0018343)
0.0 0.3 GO:0016180 snRNA processing(GO:0016180)
0.0 0.0 GO:0070358 regulation of CD8-positive, alpha-beta T cell differentiation(GO:0043376) actin polymerization-dependent cell motility(GO:0070358) positive regulation of CD8-positive, alpha-beta T cell activation(GO:2001187)
0.0 0.1 GO:1902167 positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator(GO:1902167)
0.0 0.2 GO:0051490 negative regulation of filopodium assembly(GO:0051490)
0.0 0.0 GO:0000451 rRNA 2'-O-methylation(GO:0000451)
0.0 0.0 GO:1990022 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.0 0.0 GO:0046125 pyrimidine deoxyribonucleoside metabolic process(GO:0046125)
0.0 0.1 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.0 0.1 GO:0019659 glucose catabolic process to lactate(GO:0019659) glycolytic fermentation(GO:0019660) glucose catabolic process to lactate via pyruvate(GO:0019661)
0.0 0.0 GO:0051030 snRNA transport(GO:0051030)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0031904 endosome lumen(GO:0031904)
0.0 0.1 GO:0033597 mitotic checkpoint complex(GO:0033597) bub1-bub3 complex(GO:1990298)
0.0 0.3 GO:1990597 AIP1-IRE1 complex(GO:1990597)
0.0 0.1 GO:1903754 cortical microtubule plus-end(GO:1903754) cytoplasmic microtubule plus-end(GO:1904511)
0.0 0.2 GO:0032807 DNA ligase IV complex(GO:0032807)
0.0 0.2 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 0.1 GO:0034274 Atg12-Atg5-Atg16 complex(GO:0034274)
0.0 0.4 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 0.1 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.0 0.1 GO:0005965 protein farnesyltransferase complex(GO:0005965)
0.0 0.3 GO:0019773 proteasome core complex, alpha-subunit complex(GO:0019773)
0.0 0.1 GO:0044218 other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
0.0 0.1 GO:0005784 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0 0.1 GO:0005745 m-AAA complex(GO:0005745)
0.0 0.2 GO:0070652 HAUS complex(GO:0070652)
0.0 0.2 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.0 0.2 GO:0031597 proteasome regulatory particle, base subcomplex(GO:0008540) cytosolic proteasome complex(GO:0031597)
0.0 0.2 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.0 0.1 GO:0097342 ripoptosome(GO:0097342)
0.0 0.0 GO:0005588 collagen type V trimer(GO:0005588)
0.0 0.2 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.1 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.0 0.1 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.0 0.2 GO:0070765 gamma-secretase complex(GO:0070765)
0.0 0.1 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.0 0.2 GO:0032797 SMN complex(GO:0032797)
0.0 0.1 GO:0071817 MMXD complex(GO:0071817)
0.0 0.2 GO:0071203 WASH complex(GO:0071203)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0004066 asparagine synthase (glutamine-hydrolyzing) activity(GO:0004066)
0.1 0.3 GO:0036313 phosphatidylinositol 3-kinase catalytic subunit binding(GO:0036313)
0.1 0.2 GO:0033149 FFAT motif binding(GO:0033149)
0.1 0.3 GO:0004051 arachidonate 5-lipoxygenase activity(GO:0004051)
0.1 0.2 GO:0003881 CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity(GO:0003881)
0.0 0.1 GO:0005174 CD40 receptor binding(GO:0005174)
0.0 0.2 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.0 0.2 GO:1904121 propanoyl-CoA C-acyltransferase activity(GO:0033814) propionyl-CoA C2-trimethyltridecanoyltransferase activity(GO:0050632) phosphatidylethanolamine transporter activity(GO:1904121)
0.0 0.1 GO:0003845 11-beta-hydroxysteroid dehydrogenase [NAD(P)] activity(GO:0003845)
0.0 0.2 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.0 0.1 GO:0005171 hepatocyte growth factor receptor binding(GO:0005171)
0.0 0.1 GO:0004450 isocitrate dehydrogenase (NADP+) activity(GO:0004450)
0.0 0.1 GO:0070401 NADP+ binding(GO:0070401)
0.0 0.1 GO:0030622 U4atac snRNA binding(GO:0030622)
0.0 0.1 GO:0019776 Atg8 ligase activity(GO:0019776)
0.0 0.5 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.0 0.1 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.0 0.1 GO:0004373 glycogen (starch) synthase activity(GO:0004373)
0.0 0.1 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.0 0.1 GO:0004652 polynucleotide adenylyltransferase activity(GO:0004652)
0.0 0.1 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.0 0.1 GO:0004660 protein farnesyltransferase activity(GO:0004660)
0.0 0.1 GO:0032767 copper-dependent protein binding(GO:0032767)
0.0 0.1 GO:0004704 NF-kappaB-inducing kinase activity(GO:0004704)
0.0 0.1 GO:0004359 glutaminase activity(GO:0004359)
0.0 0.1 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.1 GO:0030942 signal recognition particle binding(GO:0005047) endoplasmic reticulum signal peptide binding(GO:0030942)
0.0 0.1 GO:0008176 tRNA (guanine-N7-)-methyltransferase activity(GO:0008176)
0.0 0.1 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.0 0.1 GO:0036132 13-prostaglandin reductase activity(GO:0036132) 15-oxoprostaglandin 13-oxidase activity(GO:0047522)
0.0 0.1 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.0 0.1 GO:0004724 magnesium-dependent protein serine/threonine phosphatase activity(GO:0004724)
0.0 0.1 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.0 0.1 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.0 0.4 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.0 0.1 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.0 0.3 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.0 GO:0001147 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160)
0.0 0.0 GO:0009383 rRNA (cytosine-C5-)-methyltransferase activity(GO:0009383)
0.0 0.1 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.0 0.1 GO:0047844 deoxycytidine deaminase activity(GO:0047844)
0.0 0.0 GO:0045142 triplex DNA binding(GO:0045142)
0.0 0.1 GO:0019767 IgE receptor activity(GO:0019767) IgG receptor activity(GO:0019770)
0.0 0.1 GO:0031419 cobalamin binding(GO:0031419)
0.0 0.1 GO:0043758 acetate-CoA ligase (ADP-forming) activity(GO:0043758)
0.0 0.1 GO:0004706 JUN kinase kinase kinase activity(GO:0004706)
0.0 0.2 GO:0031996 thioesterase binding(GO:0031996)
0.0 0.1 GO:0052901 polyamine oxidase activity(GO:0046592) spermine:oxygen oxidoreductase (spermidine-forming) activity(GO:0052901)
0.0 0.0 GO:0070039 rRNA (guanosine-2'-O-)-methyltransferase activity(GO:0070039)
0.0 0.0 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.0 0.3 GO:0070003 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.1 GO:0030171 voltage-gated proton channel activity(GO:0030171)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 PID ALK2 PATHWAY ALK2 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 REACTOME IRAK2 MEDIATED ACTIVATION OF TAK1 COMPLEX UPON TLR7 8 OR 9 STIMULATION Genes involved in IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation
0.0 0.6 REACTOME AMINO ACID SYNTHESIS AND INTERCONVERSION TRANSAMINATION Genes involved in Amino acid synthesis and interconversion (transamination)
0.0 0.3 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.0 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 0.6 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)