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avrg: GFI1 WT vs 36n/n vs KD

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Results for E2f2_E2f5

Z-value: 1.75

Motif logo

Transcription factors associated with E2f2_E2f5

Gene Symbol Gene ID Gene Info
ENSMUSG00000018983.10 E2F transcription factor 2
ENSMUSG00000027552.15 E2F transcription factor 5

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
E2f2mm39_v1_chr4_+_135899678_1358997380.819.5e-02Click!
E2f5mm39_v1_chr3_+_14643669_14643756-0.583.0e-01Click!

Activity profile of E2f2_E2f5 motif

Sorted Z-values of E2f2_E2f5 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr13_+_21938258 3.40 ENSMUST00000091709.3
H2B clustered histone 15
chr13_+_22220000 3.24 ENSMUST00000110455.4
H2B clustered histone 12
chr13_+_21971631 3.09 ENSMUST00000110473.3
ENSMUST00000102982.2
H2B clustered histone 22
chr13_+_22227359 2.73 ENSMUST00000110452.2
H2B clustered histone 11
chr13_+_22017906 2.55 ENSMUST00000180288.2
H2B clustered histone 24
chr13_-_21900313 2.30 ENSMUST00000091756.2
H2B clustered histone 13
chr13_-_23929490 2.30 ENSMUST00000091752.5
H3 clustered histone 3
chr13_-_23758370 1.90 ENSMUST00000105106.2
H2B clustered histone 7
chr13_-_23746543 1.73 ENSMUST00000105107.2
H3 clustered histone 6
chr13_-_22219738 1.72 ENSMUST00000091742.6
H2A clustered histone 12
chr13_-_21967540 1.61 ENSMUST00000189457.2
H3 clustered histone 11
chr13_-_21937997 1.60 ENSMUST00000074752.4
H2A clustered histone 15
chr13_-_21994366 1.59 ENSMUST00000091749.4
H2B clustered histone 23
chr13_-_21971388 1.59 ENSMUST00000091751.3
H2A clustered histone 22
chr3_+_96154001 1.58 ENSMUST00000176059.2
ENSMUST00000177796.2
H3 clustered histone 14
chr13_-_22017677 1.35 ENSMUST00000081342.7
H2A clustered histone 24
chr18_+_10617858 1.32 ENSMUST00000235020.2
small nuclear ribonucleoprotein D1
chr13_-_22227114 1.30 ENSMUST00000091741.6
H2A clustered histone 11
chr13_+_21906214 0.95 ENSMUST00000224651.2
H2B clustered histone 14
chr13_+_21994588 0.95 ENSMUST00000091745.6
H2A clustered histone 23
chr7_-_48530777 0.94 ENSMUST00000058745.15
E2F transcription factor 8
chr10_+_80633865 0.93 ENSMUST00000148665.8
splicing factor 3a, subunit 2
chr7_-_48531344 0.88 ENSMUST00000119223.2
E2F transcription factor 8
chr13_+_21900554 0.88 ENSMUST00000070124.5
H2A clustered histone 13
chr7_-_45045097 0.85 ENSMUST00000211121.2
ENSMUST00000074575.11
small nuclear ribonucleoprotein 70 (U1)
chr6_-_38852857 0.85 ENSMUST00000162359.8
homeodomain interacting protein kinase 2
chr9_+_100525807 0.84 ENSMUST00000133388.2
stromal antigen 1
chr12_+_11316101 0.84 ENSMUST00000218866.2
structural maintenance of chromosomes 6
chr3_+_97920819 0.81 ENSMUST00000079812.8
notch 2
chr11_+_50492899 0.77 ENSMUST00000142118.3
ENSMUST00000040523.9
a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 2
chr19_-_6134703 0.70 ENSMUST00000161548.8
zinc finger like protein 1
chr10_+_110581293 0.66 ENSMUST00000174857.8
ENSMUST00000073781.12
ENSMUST00000173471.8
ENSMUST00000173634.2
E2F transcription factor 7
chr8_-_123404811 0.66 ENSMUST00000006525.14
ENSMUST00000064674.13
CBFA2/RUNX1 translocation partner 3
chr10_-_60055082 0.64 ENSMUST00000135158.9
carbohydrate sulfotransferase 3
chr4_+_135899678 0.59 ENSMUST00000061721.6
E2F transcription factor 2
chr10_+_80634488 0.58 ENSMUST00000151928.8
splicing factor 3a, subunit 2
chr9_-_21003268 0.57 ENSMUST00000115487.3
ribonucleoprotein, PTB-binding 1
chr9_+_21458138 0.57 ENSMUST00000034703.15
ENSMUST00000115395.10
ENSMUST00000115394.8
coactivator-associated arginine methyltransferase 1
chr16_-_18066591 0.56 ENSMUST00000115645.10
RAN binding protein 1
chrX_+_41239872 0.56 ENSMUST00000123245.8
stromal antigen 2
chr5_-_106844396 0.55 ENSMUST00000137285.8
ENSMUST00000124263.2
ENSMUST00000112695.4
ENSMUST00000155495.8
ENSMUST00000135108.2
ENSMUST00000149128.3
zinc finger protein 644
predicted gene, 28039
chr9_+_100525501 0.54 ENSMUST00000146312.8
ENSMUST00000129269.8
stromal antigen 1
chr18_+_10617773 0.54 ENSMUST00000002551.5
ENSMUST00000234207.2
small nuclear ribonucleoprotein D1
chr2_-_180351778 0.54 ENSMUST00000103057.8
ENSMUST00000103055.8
death inducer-obliterator 1
chr7_+_126380655 0.53 ENSMUST00000172352.8
ENSMUST00000094037.5
T-box 6
chr6_-_38853097 0.52 ENSMUST00000161779.8
homeodomain interacting protein kinase 2
chr5_-_143846600 0.52 ENSMUST00000031613.11
ENSMUST00000100483.3
aminoacyl tRNA synthetase complex-interacting multifunctional protein 2
chr1_+_176642226 0.49 ENSMUST00000056773.15
ENSMUST00000027785.15
serologically defined colon cancer antigen 8
chr11_-_102446947 0.49 ENSMUST00000143842.2
G patch domain containing 8
chr15_-_98465516 0.49 ENSMUST00000012104.7
cyclin T1
chr4_+_84802592 0.48 ENSMUST00000102819.10
centlein, centrosomal protein
chr19_-_7194912 0.47 ENSMUST00000039758.6
cytochrome c oxidase subunit 8A
chr17_-_33979280 0.46 ENSMUST00000173860.8
RAB11B, member RAS oncogene family
chr19_+_53588808 0.46 ENSMUST00000025930.10
structural maintenance of chromosomes 3
chrX_+_93278203 0.46 ENSMUST00000153900.8
kelch-like 15
chrX_+_150799414 0.45 ENSMUST00000045312.6
structural maintenance of chromosomes 1A
chrX_+_162691978 0.45 ENSMUST00000069041.15
adaptor-related protein complex 1, sigma 2 subunit
chr9_+_100525637 0.45 ENSMUST00000041418.13
stromal antigen 1
chr11_+_58839716 0.43 ENSMUST00000078267.5
H2B.U histone 2
chr19_+_23736205 0.41 ENSMUST00000025830.9
amyloid beta (A4) precursor protein binding, family A, member 1
chr4_+_126450762 0.40 ENSMUST00000147675.2
claspin
chr13_+_23758555 0.40 ENSMUST00000090776.7
H2A clustered histone 7
chr14_-_73563212 0.39 ENSMUST00000022701.7
RB transcriptional corepressor 1
chrX_+_93278588 0.39 ENSMUST00000096369.10
ENSMUST00000113911.9
kelch-like 15
chr4_-_135080437 0.39 ENSMUST00000030613.11
ENSMUST00000131373.8
serine/arginine repetitive matrix 1
chr6_-_149003171 0.39 ENSMUST00000111557.8
DENN/MADD domain containing 5B
chr2_-_30364219 0.39 ENSMUST00000065134.4
immediate early response 5-like
chr5_-_106844685 0.37 ENSMUST00000127434.8
ENSMUST00000112696.8
ENSMUST00000112698.8
zinc finger protein 644
chr9_+_13739003 0.37 ENSMUST00000059579.12
family with sequence similarity 76, member B
chr1_-_176641607 0.37 ENSMUST00000195717.6
ENSMUST00000192961.6
centrosomal protein 170
chr2_-_32271833 0.37 ENSMUST00000146423.2
RIKEN cDNA 1110008P14 gene
chr14_+_27150750 0.35 ENSMUST00000022450.6
transcription activation suppressor
chr10_-_125225298 0.35 ENSMUST00000210780.2
solute carrier family 16 (monocarboxylic acid transporters), member 7
chr17_-_26727437 0.35 ENSMUST00000236661.2
ENSMUST00000025025.7
dual specificity phosphatase 1
chr6_-_149003003 0.34 ENSMUST00000127727.2
DENN/MADD domain containing 5B
chrX_+_47430221 0.34 ENSMUST00000136348.8
BCL6 co-repressor-like 1
chr16_+_51851917 0.34 ENSMUST00000227062.2
Casitas B-lineage lymphoma b
chr10_-_80634293 0.34 ENSMUST00000218209.2
ENSMUST00000036805.7
pleckstrin homology domain containing, family J member 1
chr16_-_76170714 0.34 ENSMUST00000231585.2
ENSMUST00000121927.8
nuclear receptor interacting protein 1
chr1_+_11484313 0.33 ENSMUST00000171690.9
ENSMUST00000048613.14
RIKEN cDNA A830018L16 gene
chr16_-_90081300 0.32 ENSMUST00000039280.9
ENSMUST00000232371.2
SR-related CTD-associated factor 4
chrX_+_137815171 0.32 ENSMUST00000064937.14
ENSMUST00000113052.8
Nik related kinase
chr15_-_58953838 0.32 ENSMUST00000080371.8
MTSS I-BAR domain containing 1
chr12_+_33197692 0.31 ENSMUST00000077456.13
ENSMUST00000110824.9
ataxin 7-like 1
chrX_+_162692126 0.31 ENSMUST00000033734.14
ENSMUST00000112294.9
adaptor-related protein complex 1, sigma 2 subunit
chr2_+_127267069 0.31 ENSMUST00000062211.4
glycerol-3-phosphate acyltransferase 2, mitochondrial
chr16_-_10131804 0.31 ENSMUST00000078357.5
epithelial membrane protein 2
chr11_-_59730569 0.31 ENSMUST00000141415.2
COP9 signalosome subunit 3
chr2_-_32271921 0.30 ENSMUST00000048792.5
RIKEN cDNA 1110008P14 gene
chr7_-_25454177 0.30 ENSMUST00000206832.2
heterogeneous nuclear ribonucleoprotein U-like 1
chr12_+_33197776 0.30 ENSMUST00000125192.9
ENSMUST00000136644.8
ataxin 7-like 1
chr2_-_45000389 0.30 ENSMUST00000201804.4
ENSMUST00000028229.13
ENSMUST00000202187.4
ENSMUST00000153561.6
ENSMUST00000201490.2
zinc finger E-box binding homeobox 2
chr2_-_26012751 0.30 ENSMUST00000140993.2
ENSMUST00000028300.6
nucleus accumbens associated 2, BEN and BTB (POZ) domain containing
chr2_-_45000250 0.30 ENSMUST00000201211.4
ENSMUST00000177302.8
zinc finger E-box binding homeobox 2
chr11_-_62349334 0.29 ENSMUST00000141447.2
nuclear receptor co-repressor 1
chr11_+_77353218 0.29 ENSMUST00000102493.8
coronin 6
chr16_-_90081188 0.29 ENSMUST00000163419.9
SR-related CTD-associated factor 4
chr4_+_132766793 0.29 ENSMUST00000105914.2
AT hook, DNA binding motif, containing 1
chr4_-_135080471 0.29 ENSMUST00000084846.12
ENSMUST00000136342.9
ENSMUST00000105861.8
serine/arginine repetitive matrix 1
chr2_+_91480513 0.28 ENSMUST00000090614.11
Rho GTPase activating protein 1
chr12_+_33197753 0.28 ENSMUST00000146040.9
ataxin 7-like 1
chr3_-_95125051 0.26 ENSMUST00000107204.8
GA repeat binding protein, beta 2
chr5_+_137786031 0.26 ENSMUST00000035852.14
zinc finger, CW type with PWWP domain 1
chr12_-_72455708 0.26 ENSMUST00000078505.14
reticulon 1
chr11_+_62349238 0.26 ENSMUST00000014389.6
phosphatidylinositol glycan anchor biosynthesis, class L
chr19_+_6413840 0.26 ENSMUST00000113488.8
ENSMUST00000113487.8
splicing factor 1
chr8_+_83891972 0.26 ENSMUST00000034145.11
TBC1 domain family, member 9
chr1_-_86287080 0.25 ENSMUST00000027438.8
nucleolin
chr8_+_84874654 0.25 ENSMUST00000143833.8
ENSMUST00000118856.8
break repair meiotic recombinase recruitment factor 1
chr6_+_8259288 0.25 ENSMUST00000159335.8
UMAP1-MVP12 associated (UMA) domain containing 1
chr9_-_102231884 0.25 ENSMUST00000035129.14
ENSMUST00000085169.12
ENSMUST00000149800.3
Eph receptor B1
chr7_+_44465714 0.24 ENSMUST00000208172.2
nucleoporin 62
chr1_-_64776890 0.24 ENSMUST00000116133.4
ENSMUST00000063982.7
frizzled class receptor 5
chr17_+_74835417 0.24 ENSMUST00000182944.8
ENSMUST00000182597.8
ENSMUST00000182133.8
ENSMUST00000183224.8
baculoviral IAP repeat-containing 6
chr15_-_97991114 0.24 ENSMUST00000180657.2
SUMO1/sentrin specific peptidase 1
chr17_-_36568728 0.24 ENSMUST00000077535.5
ribonuclease P 21 subunit
chr6_+_119152210 0.24 ENSMUST00000112777.9
ENSMUST00000073909.6
decapping mRNA 1B
chr8_+_69333143 0.24 ENSMUST00000015712.15
lipoprotein lipase
chr11_-_101875575 0.23 ENSMUST00000176261.2
ENSMUST00000143177.2
ENSMUST00000003612.13
dual specificity phosphatase 3 (vaccinia virus phosphatase VH1-related)
chr2_+_69553384 0.23 ENSMUST00000040915.15
peptidyl-prolyl isomerase G (cyclophilin G)
chr15_+_30172716 0.23 ENSMUST00000081728.7
catenin (cadherin associated protein), delta 2
chr1_+_131838220 0.23 ENSMUST00000189946.7
nuclear casein kinase and cyclin-dependent kinase substrate 1
chr19_+_6413703 0.23 ENSMUST00000131252.8
ENSMUST00000113489.8
splicing factor 1
chr7_-_25454126 0.23 ENSMUST00000108401.3
ENSMUST00000043765.14
heterogeneous nuclear ribonucleoprotein U-like 1
chr2_+_69553141 0.23 ENSMUST00000090858.10
peptidyl-prolyl isomerase G (cyclophilin G)
chr19_-_6134903 0.22 ENSMUST00000160977.8
ENSMUST00000159859.2
ENSMUST00000025707.9
ENSMUST00000160712.8
ENSMUST00000237738.2
zinc finger like protein 1
chr15_+_82183143 0.22 ENSMUST00000023089.5
WBP2 N-terminal like
chr2_+_91480460 0.21 ENSMUST00000111331.9
Rho GTPase activating protein 1
chrX_+_93278526 0.21 ENSMUST00000113908.8
ENSMUST00000113916.10
kelch-like 15
chr5_-_136596299 0.21 ENSMUST00000004097.16
cut-like homeobox 1
chr7_+_29931309 0.21 ENSMUST00000019882.16
ENSMUST00000149654.8
polymerase (RNA) II (DNA directed) polypeptide I
chr4_+_99082131 0.21 ENSMUST00000030279.15
autophagy related 4C, cysteine peptidase
chr5_-_136596094 0.21 ENSMUST00000175975.9
ENSMUST00000176216.9
ENSMUST00000176745.8
cut-like homeobox 1
chr13_-_96269076 0.21 ENSMUST00000161263.8
synaptic vesicle glycoprotein 2c
chr9_+_44245981 0.20 ENSMUST00000052686.4
H2A.X variant histone
chr8_+_84874881 0.20 ENSMUST00000093375.5
break repair meiotic recombinase recruitment factor 1
chr17_-_23959334 0.20 ENSMUST00000024702.5
progestin and adipoQ receptor family member IV
chr14_-_67106037 0.20 ENSMUST00000022629.9
dihydropyrimidinase-like 2
chr1_-_74544946 0.19 ENSMUST00000044260.11
ENSMUST00000186282.7
ubiquitin specific peptidase 37
chr18_-_80756273 0.19 ENSMUST00000078049.12
ENSMUST00000236711.2
nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 1
chr1_-_38168801 0.19 ENSMUST00000195383.2
REV1, DNA directed polymerase
chr8_-_84874468 0.19 ENSMUST00000117424.9
ENSMUST00000040383.9
coiled-coil and C2 domain containing 1A
chr3_-_116388334 0.18 ENSMUST00000197190.5
ENSMUST00000198454.2
tRNA methyltransferase 13
chr7_+_19093665 0.18 ENSMUST00000140836.8
protein phosphatase 1, regulatory subunit 13 like
chr18_-_16942289 0.18 ENSMUST00000025166.14
cadherin 2
chr1_+_191307748 0.18 ENSMUST00000045450.7
integrator complex subunit 7
chr15_+_61857226 0.18 ENSMUST00000161976.8
ENSMUST00000022971.8
myelocytomatosis oncogene
chr9_+_122780111 0.18 ENSMUST00000040717.7
ENSMUST00000214652.2
ENSMUST00000217401.2
kinesin family member 15
chr2_-_58990967 0.18 ENSMUST00000226455.2
ENSMUST00000077687.6
coiled-coil domain containing 148
chr13_+_54769611 0.17 ENSMUST00000026991.16
ENSMUST00000137413.8
ENSMUST00000135232.8
ENSMUST00000124752.2
Fas associated factor family member 2
chr18_+_36693024 0.17 ENSMUST00000134146.8
ankyrin repeat and KH domain containing 1
chr15_+_78912642 0.17 ENSMUST00000180086.3
H1.0 linker histone
chr5_-_25703700 0.17 ENSMUST00000173073.8
ENSMUST00000045291.14
ENSMUST00000173174.2
lysine (K)-specific methyltransferase 2C
chr3_+_116388600 0.17 ENSMUST00000198386.5
ENSMUST00000198311.5
ENSMUST00000197335.2
SAS-6 centriolar assembly protein
chr1_+_11484489 0.17 ENSMUST00000135014.8
RIKEN cDNA A830018L16 gene
chr6_+_4601124 0.17 ENSMUST00000141359.2
CAS1 domain containing 1
chr1_+_61677977 0.16 ENSMUST00000075374.10
par-3 family cell polarity regulator beta
chr7_-_16348862 0.16 ENSMUST00000171937.2
ENSMUST00000075845.11
Rho GTPase activating protein 35
chr15_-_8473918 0.16 ENSMUST00000052965.8
NIPBL cohesin loading factor
chr9_+_61280501 0.16 ENSMUST00000162583.8
ENSMUST00000161993.8
ENSMUST00000160882.8
ENSMUST00000160724.8
ENSMUST00000162973.8
ENSMUST00000159050.8
transducin-like enhancer of split 3
chr2_+_53082079 0.16 ENSMUST00000028336.7
ADP-ribosylation factor-like 6 interacting protein 6
chr9_+_61280764 0.16 ENSMUST00000160541.8
ENSMUST00000161207.8
ENSMUST00000159630.8
transducin-like enhancer of split 3
chrX_+_150586309 0.16 ENSMUST00000026292.15
HECT, UBA and WWE domain containing 1
chr8_-_89088782 0.15 ENSMUST00000034085.8
bromodomain containing 7
chr18_-_35760260 0.15 ENSMUST00000025212.8
solute carrier family 23 (nucleobase transporters), member 1
chr9_-_63929308 0.15 ENSMUST00000179458.2
ENSMUST00000041029.6
SMAD family member 6
chr5_-_135518098 0.15 ENSMUST00000201998.2
huntingtin interacting protein 1
chr17_-_35265514 0.15 ENSMUST00000007250.14
mutS homolog 5
chr2_+_164721277 0.15 ENSMUST00000041643.5
phosphorylated CTD interacting factor 1
chr4_+_114857370 0.14 ENSMUST00000129957.8
Scl/Tal1 interrupting locus
chr17_+_50816296 0.14 ENSMUST00000043938.8
phospholipase C-like 2
chr15_-_72932853 0.14 ENSMUST00000170633.9
ENSMUST00000228960.2
trafficking protein particle complex 9
chr18_-_38068456 0.14 ENSMUST00000080033.7
ENSMUST00000115631.8
ENSMUST00000115634.8
diaphanous related formin 1
chr3_-_151543088 0.14 ENSMUST00000029670.7
prostaglandin F receptor
chr4_+_84802513 0.14 ENSMUST00000047023.13
centlein, centrosomal protein
chr4_+_137196080 0.14 ENSMUST00000030547.15
ENSMUST00000171332.2
perlecan (heparan sulfate proteoglycan 2)
chr11_+_115921129 0.14 ENSMUST00000021116.12
ENSMUST00000106452.2
unkempt family zinc finger
chr11_-_77498636 0.14 ENSMUST00000058496.8
TAO kinase 1
chr9_+_61280890 0.13 ENSMUST00000161689.8
transducin-like enhancer of split 3
chr7_-_6733411 0.13 ENSMUST00000239104.2
ENSMUST00000051209.11
paternally expressed 3
chr19_+_46064302 0.13 ENSMUST00000165017.2
ENSMUST00000223741.2
ENSMUST00000225780.2
nucleolar and coiled-body phosphoprotein 1
chr4_+_114857348 0.13 ENSMUST00000030490.13
Scl/Tal1 interrupting locus
chr19_+_6291698 0.13 ENSMUST00000045351.13
autophagy related 2A
chr7_+_44465353 0.13 ENSMUST00000208626.2
ENSMUST00000057195.17
nucleoporin 62
chr7_+_112806672 0.13 ENSMUST00000047321.9
ENSMUST00000210074.2
ENSMUST00000210238.2
aryl hydrocarbon receptor nuclear translocator-like
chr18_-_64622092 0.13 ENSMUST00000235766.3
ENSMUST00000025484.9
ENSMUST00000237502.2
ENSMUST00000236586.3
ferrochelatase
chr15_-_57998443 0.13 ENSMUST00000038194.5
ATPase family, AAA domain containing 2
chr1_+_183766572 0.12 ENSMUST00000048655.8
dual specificity phosphatase 10
chr15_+_9140614 0.12 ENSMUST00000227556.3
LMBR1 domain containing 2
chr13_-_47259652 0.12 ENSMUST00000021807.13
ENSMUST00000135278.8
DEK proto-oncogene (DNA binding)
chr18_-_40352372 0.12 ENSMUST00000025364.6
Yip1 domain family, member 5
chr8_-_70664901 0.12 ENSMUST00000063788.8
ENSMUST00000110127.8
solute carrier family 25, member 42
chr15_+_61857390 0.12 ENSMUST00000159327.2
ENSMUST00000167731.8
myelocytomatosis oncogene
chr4_-_11966367 0.11 ENSMUST00000056050.5
ENSMUST00000108299.2
ENSMUST00000108297.3
pyruvate dehyrogenase phosphatase catalytic subunit 1
chr13_-_47259266 0.11 ENSMUST00000129352.3
DEK proto-oncogene (DNA binding)
chr18_+_31937129 0.11 ENSMUST00000082319.15
ENSMUST00000234957.2
ENSMUST00000025264.8
ENSMUST00000234344.2
WD repeat domain 33
chr5_+_65921414 0.11 ENSMUST00000201615.4
ENSMUST00000087264.4
NEDD4 binding protein 2
chr2_+_121787131 0.11 ENSMUST00000110574.8
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase like 2
chr15_-_79489286 0.11 ENSMUST00000229408.2
ENSMUST00000023065.8
DNA meiotic recombinase 1
chr18_-_38068430 0.11 ENSMUST00000025337.14
diaphanous related formin 1

Network of associatons between targets according to the STRING database.

First level regulatory network of E2f2_E2f5

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.5 GO:0032877 positive regulation of DNA endoreduplication(GO:0032877)
0.3 0.8 GO:0035622 intrahepatic bile duct development(GO:0035622) cholangiocyte proliferation(GO:1990705)
0.2 0.6 GO:0034970 histone H3-R2 methylation(GO:0034970)
0.2 0.5 GO:1903632 positive regulation of aminoacyl-tRNA ligase activity(GO:1903632)
0.2 1.4 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.2 1.1 GO:0071630 nucleus-associated proteasomal ubiquitin-dependent protein catabolic process(GO:0071630)
0.1 0.5 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.1 1.2 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.1 0.3 GO:0060720 spongiotrophoblast cell proliferation(GO:0060720) cell proliferation involved in embryonic placenta development(GO:0060722)
0.1 0.3 GO:1900477 negative regulation of G1/S transition of mitotic cell cycle by negative regulation of transcription from RNA polymerase II promoter(GO:1900477)
0.1 0.4 GO:1903944 regulation of hepatocyte apoptotic process(GO:1903943) negative regulation of hepatocyte apoptotic process(GO:1903944)
0.1 0.5 GO:1903336 negative regulation of vacuolar transport(GO:1903336)
0.1 0.5 GO:0045054 constitutive secretory pathway(GO:0045054)
0.1 0.6 GO:1902748 positive regulation of lens fiber cell differentiation(GO:1902748)
0.1 0.3 GO:0001543 ovarian follicle rupture(GO:0001543)
0.1 0.3 GO:0002337 B-1a B cell differentiation(GO:0002337)
0.1 0.3 GO:0019046 release from viral latency(GO:0019046) regulation of DNA strand elongation(GO:0060382)
0.1 0.2 GO:0060061 Spemann organizer formation(GO:0060061) syncytiotrophoblast cell differentiation involved in labyrinthine layer development(GO:0060715)
0.1 0.3 GO:0090096 lactic acid secretion(GO:0046722) regulation of metanephric cap mesenchymal cell proliferation(GO:0090095) positive regulation of metanephric cap mesenchymal cell proliferation(GO:0090096)
0.1 0.3 GO:0072362 regulation of glycolytic process by negative regulation of transcription from RNA polymerase II promoter(GO:0072362)
0.1 0.4 GO:1903438 regulation of cytokinetic process(GO:0032954) regulation of mitotic cytokinetic process(GO:1903436) positive regulation of mitotic cytokinetic process(GO:1903438) positive regulation of mitotic cytokinesis(GO:1903490)
0.1 0.5 GO:0014043 negative regulation of neuron maturation(GO:0014043)
0.1 0.6 GO:0030206 chondroitin sulfate biosynthetic process(GO:0030206)
0.1 0.7 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.1 0.3 GO:0034334 adherens junction maintenance(GO:0034334)
0.1 0.4 GO:1901475 pyruvate transmembrane transport(GO:1901475)
0.0 0.1 GO:0015882 L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904)
0.0 0.1 GO:0071799 response to prostaglandin D(GO:0071798) cellular response to prostaglandin D stimulus(GO:0071799)
0.0 0.5 GO:1901409 negative regulation of mRNA polyadenylation(GO:1900364) positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0 1.9 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 0.2 GO:0003349 epicardium-derived cardiac endothelial cell differentiation(GO:0003349)
0.0 0.1 GO:1901642 purine nucleoside transmembrane transport(GO:0015860) nucleoside transmembrane transport(GO:1901642)
0.0 0.3 GO:1990086 lens fiber cell apoptotic process(GO:1990086)
0.0 0.2 GO:0044838 cell quiescence(GO:0044838)
0.0 0.1 GO:0007352 zygotic specification of dorsal/ventral axis(GO:0007352)
0.0 0.1 GO:2000588 positive regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000588)
0.0 0.3 GO:0002913 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.0 0.2 GO:0055096 lipoprotein particle mediated signaling(GO:0055095) low-density lipoprotein particle mediated signaling(GO:0055096)
0.0 0.1 GO:1901254 regulation of translation at synapse, modulating synaptic transmission(GO:0099547) regulation of translation at postsynapse, modulating synaptic transmission(GO:0099578) positive regulation of intracellular transport of viral material(GO:1901254)
0.0 0.2 GO:1902897 regulation of postsynaptic density protein 95 clustering(GO:1902897)
0.0 0.8 GO:0030574 collagen catabolic process(GO:0030574)
0.0 0.2 GO:0051697 protein delipidation(GO:0051697)
0.0 0.5 GO:0030238 male sex determination(GO:0030238)
0.0 0.3 GO:0006072 glycerol-3-phosphate metabolic process(GO:0006072)
0.0 0.3 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 0.2 GO:2001015 negative regulation of skeletal muscle cell differentiation(GO:2001015)
0.0 0.2 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.0 0.1 GO:0090403 oxidative stress-induced premature senescence(GO:0090403)
0.0 0.1 GO:0046501 protoporphyrinogen IX metabolic process(GO:0046501)
0.0 0.1 GO:1904092 regulation of autophagic cell death(GO:1904092) negative regulation of autophagic cell death(GO:1904093)
0.0 0.1 GO:1990764 regulation of myofibroblast contraction(GO:1904328) myofibroblast contraction(GO:1990764)
0.0 0.1 GO:1900220 semaphorin-plexin signaling pathway involved in bone trabecula morphogenesis(GO:1900220)
0.0 0.9 GO:0048026 positive regulation of mRNA splicing, via spliceosome(GO:0048026)
0.0 0.2 GO:0032237 activation of store-operated calcium channel activity(GO:0032237)
0.0 0.2 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.0 0.3 GO:0033504 floor plate development(GO:0033504)
0.0 0.2 GO:0061010 gall bladder development(GO:0061010)
0.0 0.3 GO:1901838 positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838)
0.0 0.4 GO:0000188 inactivation of MAPK activity(GO:0000188)
0.0 0.3 GO:0060318 definitive erythrocyte differentiation(GO:0060318)
0.0 0.2 GO:0006283 transcription-coupled nucleotide-excision repair(GO:0006283)
0.0 0.3 GO:2001212 caveola assembly(GO:0070836) regulation of vasculogenesis(GO:2001212)
0.0 0.1 GO:2000016 negative regulation of determination of dorsal identity(GO:2000016)
0.0 0.1 GO:0042262 DNA protection(GO:0042262)
0.0 0.1 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.2 GO:0007000 nucleolus organization(GO:0007000)
0.0 0.0 GO:0019859 pyrimidine nucleobase catabolic process(GO:0006208) thymine catabolic process(GO:0006210) thymine metabolic process(GO:0019859)
0.0 0.1 GO:0055005 ventricular cardiac myofibril assembly(GO:0055005)
0.0 0.4 GO:0014051 gamma-aminobutyric acid secretion(GO:0014051)
0.0 0.2 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.0 0.2 GO:0007343 egg activation(GO:0007343)
0.0 0.2 GO:0034472 snRNA 3'-end processing(GO:0034472)
0.0 0.0 GO:1900109 regulation of histone H3-K9 dimethylation(GO:1900109)
0.0 0.3 GO:0034389 lipid particle organization(GO:0034389)
0.0 0.1 GO:0010793 regulation of mRNA export from nucleus(GO:0010793)
0.0 0.1 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.0 0.2 GO:0060712 spongiotrophoblast layer development(GO:0060712)
0.0 0.1 GO:0034184 positive regulation of maintenance of mitotic sister chromatid cohesion(GO:0034184) protein localization to site of double-strand break(GO:1990166)
0.0 0.1 GO:0090080 positive regulation of MAPKKK cascade by fibroblast growth factor receptor signaling pathway(GO:0090080)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.9 GO:0034715 pICln-Sm protein complex(GO:0034715)
0.2 0.9 GO:0035061 interchromatin granule(GO:0035061)
0.2 0.9 GO:0030893 meiotic cohesin complex(GO:0030893)
0.1 2.4 GO:0071004 U2-type prespliceosome(GO:0071004)
0.1 0.5 GO:0097443 sorting endosome(GO:0097443)
0.1 0.9 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.0 0.4 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.0 0.5 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.1 GO:0098890 extrinsic component of postsynaptic membrane(GO:0098890)
0.0 0.6 GO:1904115 axon cytoplasm(GO:1904115)
0.0 0.2 GO:0098536 deuterosome(GO:0098536)
0.0 0.1 GO:0019034 viral replication complex(GO:0019034) dendritic filopodium(GO:1902737)
0.0 0.2 GO:0005655 nucleolar ribonuclease P complex(GO:0005655)
0.0 0.1 GO:0032156 septin cytoskeleton(GO:0032156)
0.0 0.1 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 0.2 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 0.3 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 0.3 GO:0016580 Sin3 complex(GO:0016580)
0.0 0.5 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.3 GO:0090545 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.1 GO:0000308 cytoplasmic cyclin-dependent protein kinase holoenzyme complex(GO:0000308)
0.0 0.2 GO:0042627 chylomicron(GO:0042627)
0.0 0.1 GO:0001651 dense fibrillar component(GO:0001651)
0.0 0.1 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.2 GO:0032433 filopodium tip(GO:0032433)
0.0 1.0 GO:0031463 Cul3-RING ubiquitin ligase complex(GO:0031463)
0.0 1.3 GO:0005814 centriole(GO:0005814)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.1 GO:0036033 mediator complex binding(GO:0036033)
0.2 2.8 GO:1990446 U1 snRNP binding(GO:1990446)
0.1 0.6 GO:0034481 chondroitin sulfotransferase activity(GO:0034481)
0.1 0.5 GO:0045131 pre-mRNA branch point binding(GO:0045131)
0.1 0.3 GO:0008330 protein tyrosine/threonine phosphatase activity(GO:0008330)
0.1 1.4 GO:0046790 virion binding(GO:0046790)
0.1 0.2 GO:0070137 ubiquitin-like protein-specific endopeptidase activity(GO:0070137) SUMO-specific endopeptidase activity(GO:0070139)
0.1 0.6 GO:0035242 protein-arginine omega-N asymmetric methyltransferase activity(GO:0035242)
0.1 0.4 GO:0051425 PTB domain binding(GO:0051425)
0.1 0.4 GO:0050833 pyruvate transmembrane transporter activity(GO:0050833)
0.0 0.1 GO:0015229 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.0 0.1 GO:0070698 type I activin receptor binding(GO:0070698)
0.0 0.1 GO:0004958 prostaglandin F receptor activity(GO:0004958)
0.0 0.4 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.0 0.1 GO:0030350 iron-responsive element binding(GO:0030350)
0.0 0.5 GO:0097322 7SK snRNA binding(GO:0097322)
0.0 0.3 GO:0004366 glycerol-3-phosphate O-acyltransferase activity(GO:0004366)
0.0 0.2 GO:0001225 RNA polymerase II transcription coactivator binding(GO:0001225)
0.0 0.3 GO:0042134 rRNA primary transcript binding(GO:0042134)
0.0 0.2 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.2 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.0 0.3 GO:0035033 histone deacetylase regulator activity(GO:0035033)
0.0 0.1 GO:0004741 [pyruvate dehydrogenase (lipoamide)] phosphatase activity(GO:0004741)
0.0 0.1 GO:0017150 tRNA dihydrouridine synthase activity(GO:0017150)
0.0 0.1 GO:0051185 coenzyme transporter activity(GO:0051185)
0.0 0.4 GO:0033549 MAP kinase phosphatase activity(GO:0033549)
0.0 0.6 GO:0005092 GDP-dissociation inhibitor activity(GO:0005092)
0.0 0.3 GO:0035473 lipase binding(GO:0035473)
0.0 0.6 GO:0031489 myosin V binding(GO:0031489)
0.0 0.1 GO:0004566 beta-glucuronidase activity(GO:0004566)
0.0 0.1 GO:0046404 ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity(GO:0046404) polydeoxyribonucleotide kinase activity(GO:0051733) ATP-dependent polynucleotide kinase activity(GO:0051734)
0.0 0.8 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.2 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.1 GO:0016934 extracellular-glycine-gated ion channel activity(GO:0016933) extracellular-glycine-gated chloride channel activity(GO:0016934)
0.0 0.1 GO:0005047 signal recognition particle binding(GO:0005047)
0.0 0.3 GO:0005522 profilin binding(GO:0005522)
0.0 0.2 GO:0004806 triglyceride lipase activity(GO:0004806)
0.0 0.6 GO:0070412 R-SMAD binding(GO:0070412)
0.0 0.7 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.2 GO:0015279 store-operated calcium channel activity(GO:0015279)
0.0 0.1 GO:0050220 prostaglandin-E synthase activity(GO:0050220)
0.0 0.1 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 0.1 GO:0033592 RNA strand annealing activity(GO:0033592)
0.0 0.1 GO:0043533 inositol 1,3,4,5 tetrakisphosphate binding(GO:0043533)
0.0 0.2 GO:0042813 Wnt-activated receptor activity(GO:0042813)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.8 PID AR TF PATHWAY Regulation of Androgen receptor activity
0.0 1.0 PID ERBB4 PATHWAY ErbB4 signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.5 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.1 0.8 REACTOME RECEPTOR LIGAND BINDING INITIATES THE SECOND PROTEOLYTIC CLEAVAGE OF NOTCH RECEPTOR Genes involved in Receptor-ligand binding initiates the second proteolytic cleavage of Notch receptor
0.1 0.8 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 1.8 REACTOME METABOLISM OF NON CODING RNA Genes involved in Metabolism of non-coding RNA
0.0 0.6 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.4 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.1 REACTOME ERK MAPK TARGETS Genes involved in ERK/MAPK targets
0.0 0.5 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.1 REACTOME PROSTANOID LIGAND RECEPTORS Genes involved in Prostanoid ligand receptors
0.0 0.4 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.2 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.2 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 1.0 REACTOME NOTCH1 INTRACELLULAR DOMAIN REGULATES TRANSCRIPTION Genes involved in NOTCH1 Intracellular Domain Regulates Transcription
0.0 0.7 REACTOME COLLAGEN FORMATION Genes involved in Collagen formation
0.0 0.4 REACTOME LOSS OF NLP FROM MITOTIC CENTROSOMES Genes involved in Loss of Nlp from mitotic centrosomes