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avrg: GFI1 WT vs 36n/n vs KD

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Results for E2f3

Z-value: 1.78

Motif logo

Transcription factors associated with E2f3

Gene Symbol Gene ID Gene Info
ENSMUSG00000016477.19 E2F transcription factor 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
E2f3mm39_v1_chr13_-_30170031_301700481.003.6e-05Click!

Activity profile of E2f3 motif

Sorted Z-values of E2f3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr15_-_79967543 1.47 ENSMUST00000081650.15
ribosomal protein L3
chr12_+_24758968 1.39 ENSMUST00000154588.2
ribonucleotide reductase M2
chr1_-_91340884 1.17 ENSMUST00000086851.2
hairy and enhancer of split 6
chr12_+_24758724 1.01 ENSMUST00000153058.8
ribonucleotide reductase M2
chr18_+_31922173 0.90 ENSMUST00000025106.5
ENSMUST00000234146.2
polymerase (RNA) II (DNA directed) polypeptide D
chr6_+_86342622 0.87 ENSMUST00000071492.9
family with sequence similarity 136, member A
chr5_-_65855511 0.85 ENSMUST00000201948.4
PDS5 cohesin associated factor A
chr12_+_24758240 0.85 ENSMUST00000020980.12
ribonucleotide reductase M2
chr3_-_84063067 0.77 ENSMUST00000047368.8
meiotic nuclear divisions 1
chr10_-_34003933 0.75 ENSMUST00000062784.8
calcium homeostasis modulator family member 6
chr4_+_132495636 0.72 ENSMUST00000102561.11
replication protein A2
chr2_+_150751475 0.72 ENSMUST00000028948.5
GINS complex subunit 1 (Psf1 homolog)
chr11_+_115455260 0.65 ENSMUST00000021085.11
nucleoporin 85
chr2_+_127112613 0.62 ENSMUST00000125049.2
ENSMUST00000110374.2
START domain containing 7
chr3_+_10077608 0.57 ENSMUST00000029046.9
fatty acid binding protein 5, epidermal
chr2_+_31560725 0.53 ENSMUST00000038474.14
ENSMUST00000137156.2
exosome component 2
chr1_-_66902429 0.53 ENSMUST00000027153.6
acyl-Coenzyme A dehydrogenase, long-chain
chr5_-_100867520 0.52 ENSMUST00000112908.2
ENSMUST00000045617.15
heparanase
chr18_+_47245204 0.49 ENSMUST00000234633.2
heat shock protein 1 (chaperonin 10), related sequence 1
chr16_-_4536992 0.49 ENSMUST00000115851.10
NmrA-like family domain containing 1
chr17_+_29251602 0.48 ENSMUST00000130216.3
serine and arginine-rich splicing factor 3
chr16_-_91443794 0.48 ENSMUST00000232367.2
ENSMUST00000231380.2
ENSMUST00000231444.2
ENSMUST00000232289.2
ENSMUST00000120450.2
ENSMUST00000023684.14
phosphoribosylglycinamide formyltransferase
chr11_+_21189277 0.47 ENSMUST00000109578.8
ENSMUST00000006221.14
VPS54 GARP complex subunit
chrX_-_101232978 0.47 ENSMUST00000033683.8
ribosomal protein S4, X-linked
chr3_-_95125190 0.47 ENSMUST00000136139.8
GA repeat binding protein, beta 2
chr4_-_108436514 0.47 ENSMUST00000079213.6
PRP38 pre-mRNA processing factor 38 (yeast) domain containing A
chr4_+_131570770 0.43 ENSMUST00000030742.11
ENSMUST00000137321.3
mitochondrial trans-2-enoyl-CoA reductase
chr1_-_39616369 0.42 ENSMUST00000195705.2
ring finger protein 149
chr6_-_34887743 0.42 ENSMUST00000081214.12
WD repeat domain 91
chr3_+_96542933 0.40 ENSMUST00000048766.15
peroxisomal biogenesis factor 11 beta
chr9_+_64188857 0.40 ENSMUST00000215031.2
ENSMUST00000213165.2
ENSMUST00000213289.2
ENSMUST00000216594.2
ENSMUST00000034964.7
timeless interacting protein
chr5_-_123038329 0.40 ENSMUST00000031435.14
lysine (K)-specific demethylase 2B
chr8_-_124586159 0.40 ENSMUST00000034452.12
centriole, cilia and spindle associated protein
chr18_+_74912268 0.39 ENSMUST00000041053.11
acetyl-Coenzyme A acyltransferase 2 (mitochondrial 3-oxoacyl-Coenzyme A thiolase)
chr19_+_3373285 0.39 ENSMUST00000025835.6
carnitine palmitoyltransferase 1a, liver
chr17_+_34258411 0.39 ENSMUST00000087497.11
ENSMUST00000131134.9
ENSMUST00000235819.2
ENSMUST00000114255.9
ENSMUST00000114252.9
ENSMUST00000237989.2
collagen, type XI, alpha 2
chr1_-_91326490 0.39 ENSMUST00000190519.2
ENSMUST00000027534.13
ENSMUST00000187306.7
integrin-linked kinase-associated serine/threonine phosphatase 2C
chr8_+_106587268 0.38 ENSMUST00000212610.2
ENSMUST00000212484.2
ENSMUST00000212200.2
nuclear transport factor 2
chr10_-_71180763 0.38 ENSMUST00000045887.9
CDGSH iron sulfur domain 1
chr19_+_5416769 0.37 ENSMUST00000025759.9
eukaryotic translation initiation factor 1A domain containing
chr10_-_60983438 0.36 ENSMUST00000092498.12
ENSMUST00000137833.2
ENSMUST00000155919.8
sphingosine phosphate lyase 1
chr11_-_101442663 0.36 ENSMUST00000017290.11
breast cancer 1, early onset
chr1_-_63215812 0.35 ENSMUST00000185847.2
ENSMUST00000185732.7
ENSMUST00000188370.7
ENSMUST00000168099.9
NADH:ubiquinone oxidoreductase core subunit S1
chr14_-_47805861 0.35 ENSMUST00000228784.2
ENSMUST00000042988.7
autophagy related 14
chr11_-_84020382 0.35 ENSMUST00000018795.13
transcriptional adaptor 2A
chr3_+_81839908 0.35 ENSMUST00000029649.3
cathepsin O
chr16_-_4536943 0.35 ENSMUST00000120056.8
ENSMUST00000074970.8
NmrA-like family domain containing 1
chr1_-_135241429 0.35 ENSMUST00000134088.3
ENSMUST00000081104.10
translocase of inner mitochondrial membrane 17a
chr2_-_24864998 0.35 ENSMUST00000194392.2
mitochondrial ribosomal protein L41
chr3_+_96543143 0.35 ENSMUST00000165842.3
peroxisomal biogenesis factor 11 beta
chr3_-_65300000 0.35 ENSMUST00000029414.12
signal sequence receptor, gamma
chr1_+_156386414 0.35 ENSMUST00000166172.9
ENSMUST00000027888.13
v-abl Abelson murine leukemia viral oncogene 2 (arg, Abelson-related gene)
chr7_+_140461860 0.34 ENSMUST00000026560.14
proteasome (prosome, macropain) 26S subunit, non-ATPase, 13
chr3_-_121608859 0.34 ENSMUST00000029770.8
ATP-binding cassette, sub-family D (ALD), member 3
chr2_+_144398226 0.34 ENSMUST00000155876.8
ENSMUST00000149697.3
SEC23 homolog B, COPII coat complex component
chr17_+_36152559 0.34 ENSMUST00000174124.2
mediator of DNA damage checkpoint 1
chr18_+_11790409 0.33 ENSMUST00000047322.8
retinoblastoma binding protein 8, endonuclease
chr10_+_80062468 0.33 ENSMUST00000130260.2
PWWP domain containing 3A, DNA repair factor
chr3_-_65299967 0.33 ENSMUST00000119896.2
signal sequence receptor, gamma
chr9_-_98483695 0.33 ENSMUST00000035034.10
mitochondrial ribosomal protein S22
chr1_-_128287347 0.33 ENSMUST00000190495.2
ENSMUST00000027601.11
minichromosome maintenance complex component 6
chr16_-_87229485 0.32 ENSMUST00000039449.9
listerin E3 ubiquitin protein ligase 1
chr13_+_54722833 0.32 ENSMUST00000156024.2
ADP-ribosylation factor-like 10
chr16_-_22258469 0.32 ENSMUST00000079601.13
ets variant 5
chr5_-_92653377 0.32 ENSMUST00000031377.9
scavenger receptor class B, member 2
chr3_-_95125002 0.32 ENSMUST00000107209.8
GA repeat binding protein, beta 2
chr13_-_21586858 0.32 ENSMUST00000117721.8
ENSMUST00000070785.16
ENSMUST00000116433.2
ENSMUST00000223831.2
ENSMUST00000116434.11
ENSMUST00000224820.2
zinc finger with KRAB and SCAN domains 3
chr7_+_34818709 0.32 ENSMUST00000205391.2
ENSMUST00000042985.11
CCAAT/enhancer binding protein (C/EBP), alpha
chr12_+_111505253 0.31 ENSMUST00000220803.2
eukaryotic translation initiation factor 5
chr3_-_94949854 0.31 ENSMUST00000117355.2
ENSMUST00000071664.12
ENSMUST00000107237.8
proteasome (prosome, macropain) 26S subunit, non-ATPase, 4
chr15_-_79430942 0.31 ENSMUST00000054014.9
ENSMUST00000229877.2
DEAD box helicase 17
chr8_-_57940834 0.30 ENSMUST00000034022.4
sin3 associated polypeptide
chr2_+_144398149 0.30 ENSMUST00000143573.8
ENSMUST00000028916.15
ENSMUST00000155258.2
SEC23 homolog B, COPII coat complex component
chr3_-_121608809 0.29 ENSMUST00000197383.5
ATP-binding cassette, sub-family D (ALD), member 3
chr10_-_80754016 0.28 ENSMUST00000057623.14
ENSMUST00000179022.8
lamin B2
chrX_+_20570145 0.27 ENSMUST00000033383.3
ubiquitin specific peptidase 11
chr2_-_118987305 0.27 ENSMUST00000135419.8
ENSMUST00000129351.2
ENSMUST00000139519.2
ENSMUST00000094695.12
regulator of microtubule dynamics 3
chr9_+_55949141 0.26 ENSMUST00000114276.3
reticulocalbin 2
chr7_-_140462221 0.26 ENSMUST00000026559.14
sirtuin 3
chr6_-_72322116 0.25 ENSMUST00000070345.5
ubiquitin specific peptidase 39
chr2_+_28531239 0.25 ENSMUST00000028155.12
ENSMUST00000113869.8
ENSMUST00000113867.9
TSC complex subunit 1
chr8_-_120331936 0.25 ENSMUST00000093099.13
TATA-box binding protein associated factor, RNA polymerase I, C
chr9_+_63509925 0.25 ENSMUST00000041551.9
alpha- and gamma-adaptin binding protein
chr8_-_35432783 0.25 ENSMUST00000033929.6
tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase
chr12_-_81468705 0.24 ENSMUST00000085319.4
a disintegrin and metallopeptidase domain 4
chr3_+_33853941 0.24 ENSMUST00000099153.10
tetratricopeptide repeat domain 14
chr6_+_29768470 0.24 ENSMUST00000102995.9
ENSMUST00000115242.9
S-adenosylhomocysteine hydrolase-like 2
chr16_-_87229367 0.23 ENSMUST00000232095.2
listerin E3 ubiquitin protein ligase 1
chr2_+_150628655 0.23 ENSMUST00000045441.8
brain glycogen phosphorylase
chr10_-_30476658 0.23 ENSMUST00000019927.7
tRNA methyltransferase 11
chr6_-_71417607 0.23 ENSMUST00000002292.15
required for meiotic nuclear division 5 homolog A
chr13_-_53135064 0.22 ENSMUST00000071065.8
nuclear factor, interleukin 3, regulated
chr16_-_43709968 0.22 ENSMUST00000023387.14
queuine tRNA-ribosyltransferase accessory subunit 2
chr1_-_63215952 0.22 ENSMUST00000185412.7
ENSMUST00000027111.15
ENSMUST00000189664.2
NADH:ubiquinone oxidoreductase core subunit S1
chr12_+_24701273 0.21 ENSMUST00000020982.7
Kruppel-like factor 11
chr2_-_120183575 0.21 ENSMUST00000028752.8
ENSMUST00000102501.10
VPS39 HOPS complex subunit
chr7_-_140462187 0.21 ENSMUST00000211179.2
sirtuin 3
chr9_-_79700660 0.21 ENSMUST00000034878.12
transmembrane protein 30A
chr9_-_72892617 0.20 ENSMUST00000124565.3
cell cycle progression 1, opposite strand
chr7_+_97049210 0.20 ENSMUST00000032882.9
ENSMUST00000149122.2
NADH:ubiquinone oxidoreductase subunit C2
chr9_-_105372235 0.20 ENSMUST00000176190.8
ENSMUST00000163879.9
ENSMUST00000112558.10
ENSMUST00000176363.9
ATPase, Ca++-sequestering
chr12_-_69274936 0.20 ENSMUST00000221411.2
ENSMUST00000021359.7
polymerase (DNA directed), epsilon 2 (p59 subunit)
chr3_+_96542746 0.20 ENSMUST00000118557.8
peroxisomal biogenesis factor 11 beta
chr11_+_65698001 0.20 ENSMUST00000071465.9
ENSMUST00000018491.8
zinc finger with KRAB and SCAN domains 6
chr6_-_24528012 0.19 ENSMUST00000023851.9
NADH:ubiquinone oxidoreductase subunit A5
chr9_-_20888054 0.19 ENSMUST00000054197.7
sphingosine-1-phosphate receptor 2
chr7_-_140461769 0.19 ENSMUST00000106048.10
ENSMUST00000147331.9
ENSMUST00000137710.2
sirtuin 3
chr13_+_92491234 0.19 ENSMUST00000022218.6
dihydrofolate reductase
chr10_-_60983404 0.18 ENSMUST00000122259.8
sphingosine phosphate lyase 1
chr17_-_80369626 0.18 ENSMUST00000184635.8
heterogeneous nuclear ribonucleoprotein L-like
chr3_+_66893280 0.18 ENSMUST00000161726.2
ENSMUST00000160504.2
arginine/serine-rich coiled-coil 1
chr17_+_27136065 0.18 ENSMUST00000078961.6
kinesin family member C5B
chr17_-_33007238 0.18 ENSMUST00000159086.10
zinc finger protein 871
chr1_+_44187007 0.18 ENSMUST00000027214.4
excision repair cross-complementing rodent repair deficiency, complementation group 5
chr17_-_71782296 0.18 ENSMUST00000127430.2
SMC hinge domain containing 1
chr6_-_88818832 0.18 ENSMUST00000032169.8
ankyrin repeat and BTB (POZ) domain containing 1
chr1_-_16689527 0.18 ENSMUST00000182554.9
ubiquitin-conjugating enzyme E2W (putative)
chr1_-_95595280 0.17 ENSMUST00000043336.11
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4
chr7_-_45362867 0.17 ENSMUST00000211340.2
sphingosine kinase 2
chr7_-_100021514 0.17 ENSMUST00000032963.10
protein phosphatase methylesterase 1
chrX_+_73326303 0.17 ENSMUST00000069722.13
ENSMUST00000124200.8
ENSMUST00000114180.11
ENSMUST00000132437.8
tafazzin
chr4_+_43957677 0.16 ENSMUST00000107855.2
GLI pathogenesis-related 2
chr9_+_108731287 0.16 ENSMUST00000188557.8
solute carrier family 26, member 6
chr12_+_85157607 0.16 ENSMUST00000053811.10
dihydrolipoamide S-succinyltransferase (E2 component of 2-oxo-glutarate complex)
chr7_+_12568647 0.16 ENSMUST00000004614.15
zinc finger protein 110
chr1_-_16689660 0.16 ENSMUST00000117146.9
ubiquitin-conjugating enzyme E2W (putative)
chr17_-_80369762 0.16 ENSMUST00000061331.14
heterogeneous nuclear ribonucleoprotein L-like
chr10_-_80512117 0.16 ENSMUST00000200082.5
MAP kinase-interacting serine/threonine kinase 2
chr14_-_14255736 0.16 ENSMUST00000170111.3
potassium channel tetramerisation domain containing 6
chr15_-_67048595 0.15 ENSMUST00000229213.2
ST3 beta-galactoside alpha-2,3-sialyltransferase 1
chr19_-_8700728 0.15 ENSMUST00000170157.8
solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2
chr17_+_28075495 0.15 ENSMUST00000233809.2
UHRF1 (ICBP90) binding protein 1
chr10_-_62285458 0.15 ENSMUST00000020273.16
suppressor of var1, 3-like 1 (S. cerevisiae)
chr14_-_57635969 0.15 ENSMUST00000022517.9
crystallin, lambda 1
chr4_+_34614939 0.15 ENSMUST00000029968.14
ENSMUST00000148519.3
arginyl-tRNA synthetase 2, mitochondrial
chr12_-_4924341 0.15 ENSMUST00000137337.8
ENSMUST00000045921.14
major facilitator superfamily domain containing 2B
chr5_+_114706077 0.15 ENSMUST00000043650.8
family with sequence similarity 222, member A
chr10_-_90959853 0.14 ENSMUST00000170810.8
ENSMUST00000076694.13
solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 3
chr4_+_10874498 0.14 ENSMUST00000080517.14
RIKEN cDNA 2610301B20 gene
chr15_-_83479312 0.14 ENSMUST00000016901.5
tubulin tyrosine ligase-like family, member 12
chr2_-_109111064 0.14 ENSMUST00000147770.2
methyltransferase like 15
chr5_-_31350352 0.14 ENSMUST00000202758.4
ENSMUST00000114603.8
eukaryotic translation initiation factor 2B, subunit 4 delta
chr12_+_111504450 0.13 ENSMUST00000166123.9
ENSMUST00000222441.2
eukaryotic translation initiation factor 5
chr1_+_139349912 0.13 ENSMUST00000200243.5
ENSMUST00000039867.10
zinc finger and BTB domain containing 41
chr3_+_41697046 0.13 ENSMUST00000120167.8
ENSMUST00000108065.9
ENSMUST00000146165.8
ENSMUST00000192193.6
ENSMUST00000119572.8
ENSMUST00000026867.14
ENSMUST00000026868.13
DNA segment, Chr 3, ERATO Doi 751, expressed
chr19_-_4319170 0.13 ENSMUST00000037992.16
ENSMUST00000113852.6
ENSMUST00000236794.2
slingshot protein phosphatase 3
chr5_-_148336711 0.13 ENSMUST00000048116.15
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr7_-_121580930 0.13 ENSMUST00000205438.2
ENSMUST00000057576.8
component of oligomeric golgi complex 7
chr18_+_11790888 0.13 ENSMUST00000234499.2
retinoblastoma binding protein 8, endonuclease
chr3_-_68911886 0.13 ENSMUST00000169064.8
intraflagellar transport 80
chr3_-_51248032 0.12 ENSMUST00000062009.14
ENSMUST00000194641.6
E74-like factor 2
chr5_-_65855199 0.12 ENSMUST00000031104.7
PDS5 cohesin associated factor A
chr13_+_84370405 0.12 ENSMUST00000057495.10
ENSMUST00000225069.2
transmembrane protein 161B
chr6_+_71808427 0.11 ENSMUST00000171057.2
inner membrane protein, mitochondrial
chr16_+_12927547 0.11 ENSMUST00000023206.14
excision repair cross-complementing rodent repair deficiency, complementation group 4
chr8_+_123294740 0.10 ENSMUST00000006760.3
chromatin licensing and DNA replication factor 1
chr2_-_104542467 0.10 ENSMUST00000111118.8
ENSMUST00000028597.4
t-complex 11 like 1
chr12_+_8971603 0.10 ENSMUST00000020909.4
lysosomal-associated protein transmembrane 4A
chr16_+_90017634 0.10 ENSMUST00000023707.11
superoxide dismutase 1, soluble
chr4_+_3938903 0.10 ENSMUST00000121210.8
ENSMUST00000121651.8
ENSMUST00000041122.11
ENSMUST00000120732.8
ENSMUST00000119307.8
ENSMUST00000123769.8
coiled-coil-helix-coiled-coil-helix domain containing 7
chr4_-_34614883 0.10 ENSMUST00000140334.2
ENSMUST00000108142.8
ENSMUST00000048706.10
origin recognition complex, subunit 3
chr11_+_84020475 0.10 ENSMUST00000133811.3
acetyl-Coenzyme A carboxylase alpha
chr11_+_60066681 0.09 ENSMUST00000102688.2
retinoic acid induced 1
chr16_-_78173645 0.09 ENSMUST00000023570.14
BTG anti-proliferation factor 3
chr8_+_71995554 0.09 ENSMUST00000034272.9
multivesicular body subunit 12A
chr9_-_78350486 0.09 ENSMUST00000070742.14
ENSMUST00000034898.14
cyclic GMP-AMP synthase
chr19_+_38384428 0.09 ENSMUST00000054098.4
solute carrier family 35, member G1
chr4_+_11486002 0.09 ENSMUST00000108307.3
vir like m6A methyltransferase associated
chr5_+_117457126 0.09 ENSMUST00000111967.8
V-set and immunoglobulin domain containing 10
chr2_+_180240015 0.09 ENSMUST00000103059.2
collagen, type IX, alpha 3
chr5_-_148336574 0.09 ENSMUST00000202457.4
solute carrier family 7 (cationic amino acid transporter, y+ system), member 1
chr12_+_111505216 0.09 ENSMUST00000050993.11
eukaryotic translation initiation factor 5
chr1_+_90531183 0.09 ENSMUST00000186750.2
COP9 signalosome subunit 8
chr13_-_92491451 0.09 ENSMUST00000187424.2
ENSMUST00000185852.7
ENSMUST00000022220.13
mutS homolog 3
chr13_-_55477535 0.08 ENSMUST00000021941.8
Max dimerization protein 3
chr3_-_68911835 0.08 ENSMUST00000107812.8
intraflagellar transport 80
chrX_-_50294652 0.08 ENSMUST00000114875.8
muscleblind like splicing factor 3
chr3_+_33854305 0.08 ENSMUST00000196139.5
ENSMUST00000200271.5
ENSMUST00000198529.5
ENSMUST00000117915.8
ENSMUST00000108210.9
ENSMUST00000196975.5
tetratricopeptide repeat domain 14
chrX_-_104973003 0.08 ENSMUST00000130980.2
ENSMUST00000113573.8
ATRX, chromatin remodeler
chr7_+_23781311 0.08 ENSMUST00000207002.2
ENSMUST00000068975.6
ENSMUST00000203854.3
zinc finger protein 180
chr12_-_108145498 0.08 ENSMUST00000071095.14
SET domain containing 3
chr2_+_30282414 0.08 ENSMUST00000123202.8
ENSMUST00000113612.10
dolichyl pyrophosphate phosphatase 1
chr6_+_47431254 0.08 ENSMUST00000031697.9
ENSMUST00000143941.3
cullin 1
chr2_+_152804405 0.08 ENSMUST00000099197.9
ENSMUST00000103155.10
tubulin tyrosine ligase-like family, member 9
chr18_+_44513547 0.08 ENSMUST00000202306.2
ENSMUST00000025350.10
decapping mRNA 2
chr6_+_71808309 0.08 ENSMUST00000064062.13
ENSMUST00000166975.8
ENSMUST00000165331.8
ENSMUST00000114151.10
ENSMUST00000101301.10
ENSMUST00000166938.8
inner membrane protein, mitochondrial
chr11_+_101443014 0.07 ENSMUST00000147239.8
NBR1, autophagy cargo receptor
chr2_+_24944407 0.07 ENSMUST00000102931.11
ENSMUST00000074422.14
ENSMUST00000132172.8
ENSMUST00000114388.8
NMDA receptor synaptonuclear signaling and neuronal migration factor
chr3_+_66893031 0.07 ENSMUST00000046542.13
ENSMUST00000162693.8
arginine/serine-rich coiled-coil 1
chr10_+_43355113 0.06 ENSMUST00000040147.8
BEN domain containing 3
chr2_-_180929828 0.06 ENSMUST00000049032.13
glucocorticoid modulatory element binding protein 2
chr3_+_103483397 0.06 ENSMUST00000183637.8
ENSMUST00000117221.9
ENSMUST00000118117.8
ENSMUST00000118563.3
synaptotagmin VI
chr9_-_105372330 0.06 ENSMUST00000038118.15
ATPase, Ca++-sequestering
chr7_-_5016237 0.06 ENSMUST00000208944.2
Flt3 interacting zinc finger protein 1
chr18_+_9957906 0.06 ENSMUST00000025137.9
THO complex 1
chr12_+_111504640 0.06 ENSMUST00000222375.2
ENSMUST00000222388.2
eukaryotic translation initiation factor 5
chr7_-_100661220 0.05 ENSMUST00000207916.2
purinergic receptor P2Y, G-protein coupled 2
chr7_-_30643444 0.05 ENSMUST00000062620.9
hepcidin antimicrobial peptide
chr10_+_43354807 0.05 ENSMUST00000167488.9
BEN domain containing 3
chr18_-_52662728 0.04 ENSMUST00000025409.9
lysyl oxidase

Network of associatons between targets according to the STRING database.

First level regulatory network of E2f3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0031990 mRNA export from nucleus in response to heat stress(GO:0031990)
0.2 1.0 GO:0044375 regulation of peroxisome size(GO:0044375)
0.2 0.5 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.2 0.2 GO:1990009 retinal cell apoptotic process(GO:1990009)
0.2 0.6 GO:0015910 peroxisomal long-chain fatty acid import(GO:0015910)
0.1 3.2 GO:0009263 deoxyribonucleotide biosynthetic process(GO:0009263)
0.1 0.5 GO:0071043 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.1 0.5 GO:0042758 long-chain fatty acid catabolic process(GO:0042758)
0.1 0.1 GO:0071163 DNA replication preinitiation complex assembly(GO:0071163)
0.1 0.4 GO:0021993 initiation of neural tube closure(GO:0021993)
0.1 0.4 GO:1902109 negative regulation of mitochondrial membrane permeability involved in apoptotic process(GO:1902109)
0.1 0.1 GO:0006267 pre-replicative complex assembly involved in nuclear cell cycle DNA replication(GO:0006267) pre-replicative complex assembly(GO:0036388) pre-replicative complex assembly involved in cell cycle DNA replication(GO:1902299)
0.1 0.5 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.1 0.3 GO:0006295 nucleotide-excision repair, DNA incision, 3'-to lesion(GO:0006295)
0.1 0.4 GO:0016240 autophagosome docking(GO:0016240)
0.1 0.3 GO:0090650 rRNA export from nucleus(GO:0006407) response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.1 0.2 GO:1904742 regulation of telomeric DNA binding(GO:1904742)
0.1 0.4 GO:0048478 replication fork protection(GO:0048478)
0.1 0.4 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
0.1 0.7 GO:1902969 mitotic DNA replication(GO:1902969)
0.1 0.3 GO:0055071 cellular manganese ion homeostasis(GO:0030026) Golgi calcium ion homeostasis(GO:0032468) manganese ion homeostasis(GO:0055071)
0.1 0.2 GO:0060821 inactivation of X chromosome by DNA methylation(GO:0060821)
0.1 0.2 GO:0035965 cardiolipin acyl-chain remodeling(GO:0035965)
0.1 0.4 GO:0060023 soft palate development(GO:0060023)
0.1 0.2 GO:1904046 negative regulation of vascular endothelial growth factor production(GO:1904046)
0.1 0.2 GO:0046724 oxalic acid secretion(GO:0046724)
0.1 0.5 GO:0010792 DNA double-strand break processing involved in repair via single-strand annealing(GO:0010792)
0.1 0.7 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
0.0 0.2 GO:0006669 sphinganine-1-phosphate biosynthetic process(GO:0006669)
0.0 0.7 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.0 0.2 GO:1902774 late endosome to lysosome transport(GO:1902774)
0.0 0.7 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.2 GO:0042276 error-prone translesion synthesis(GO:0042276)
0.0 1.5 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.0 0.8 GO:2000001 regulation of DNA damage checkpoint(GO:2000001)
0.0 0.2 GO:0000960 mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)
0.0 0.3 GO:0048133 germ-line stem cell division(GO:0042078) male germ-line stem cell asymmetric division(GO:0048133) germline stem cell asymmetric division(GO:0098728)
0.0 0.6 GO:0060052 neurofilament cytoskeleton organization(GO:0060052)
0.0 0.6 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.0 0.2 GO:0006545 glycine biosynthetic process(GO:0006545)
0.0 0.4 GO:0033262 regulation of nuclear cell cycle DNA replication(GO:0033262)
0.0 0.2 GO:0060356 leucine import(GO:0060356)
0.0 0.1 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.1 GO:0010387 COP9 signalosome assembly(GO:0010387)
0.0 0.3 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.4 GO:0090043 tubulin deacetylation(GO:0090042) regulation of tubulin deacetylation(GO:0090043)
0.0 0.2 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 0.3 GO:0000050 urea cycle(GO:0000050)
0.0 0.4 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.0 0.5 GO:0033327 Leydig cell differentiation(GO:0033327)
0.0 0.2 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376)
0.0 0.4 GO:1901673 regulation of mitotic spindle assembly(GO:1901673)
0.0 0.6 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 0.5 GO:0006656 phosphatidylcholine biosynthetic process(GO:0006656)
0.0 0.3 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.1 GO:0099527 postsynapse to nucleus signaling pathway(GO:0099527)
0.0 0.1 GO:0044268 multicellular organismal protein metabolic process(GO:0044268)
0.0 0.1 GO:0061092 regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
0.0 0.3 GO:0033148 positive regulation of intracellular estrogen receptor signaling pathway(GO:0033148)
0.0 0.3 GO:0006622 protein targeting to lysosome(GO:0006622)
0.0 0.2 GO:0070863 positive regulation of protein exit from endoplasmic reticulum(GO:0070863)
0.0 0.1 GO:1903772 regulation of viral budding via host ESCRT complex(GO:1903772)
0.0 0.2 GO:0015809 arginine transport(GO:0015809)
0.0 0.2 GO:2000773 negative regulation of cellular senescence(GO:2000773)
0.0 0.1 GO:0098532 histone H3-K27 trimethylation(GO:0098532)
0.0 0.1 GO:0070475 rRNA base methylation(GO:0070475)
0.0 0.1 GO:0034757 negative regulation of iron ion transport(GO:0034757) negative regulation of iron ion transmembrane transport(GO:0034760)
0.0 0.1 GO:1990034 calcium ion export from cell(GO:1990034)
0.0 0.0 GO:0051309 female meiosis chromosome separation(GO:0051309)
0.0 0.4 GO:0043457 regulation of cellular respiration(GO:0043457)
0.0 0.1 GO:0051095 regulation of helicase activity(GO:0051095) positive regulation of helicase activity(GO:0051096)
0.0 0.7 GO:0035825 reciprocal meiotic recombination(GO:0007131) reciprocal DNA recombination(GO:0035825)
0.0 0.2 GO:0000083 regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0000083)
0.0 0.2 GO:0042407 cristae formation(GO:0042407)
0.0 0.7 GO:0071427 mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.0 0.7 GO:0042773 ATP synthesis coupled electron transport(GO:0042773)
0.0 0.3 GO:0071218 cellular response to misfolded protein(GO:0071218)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.2 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.2 0.7 GO:0000811 GINS complex(GO:0000811)
0.1 0.4 GO:0097632 extrinsic component of pre-autophagosomal structure membrane(GO:0097632)
0.1 0.3 GO:0036488 CHOP-C/EBP complex(GO:0036488)
0.1 0.1 GO:0031261 DNA replication preinitiation complex(GO:0031261)
0.1 0.5 GO:0000938 GARP complex(GO:0000938)
0.1 0.4 GO:0031298 replication fork protection complex(GO:0031298)
0.1 0.4 GO:0061673 mitotic spindle astral microtubule(GO:0061673)
0.1 0.4 GO:0000125 PCAF complex(GO:0000125)
0.1 0.3 GO:0043202 lysosomal lumen(GO:0043202)
0.1 0.3 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.1 0.9 GO:0005662 DNA replication factor A complex(GO:0005662)
0.1 0.1 GO:0000110 nucleotide-excision repair factor 1 complex(GO:0000110)
0.0 0.7 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.7 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 0.2 GO:0034657 GID complex(GO:0034657)
0.0 0.2 GO:0001740 Barr body(GO:0001740)
0.0 0.3 GO:0005744 mitochondrial inner membrane presequence translocase complex(GO:0005744)
0.0 0.3 GO:0000120 RNA polymerase I transcription factor complex(GO:0000120)
0.0 0.2 GO:0008622 epsilon DNA polymerase complex(GO:0008622)
0.0 0.3 GO:0005638 lamin filament(GO:0005638)
0.0 0.6 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.4 GO:0070531 BRCA1-A complex(GO:0070531)
0.0 1.0 GO:0005779 integral component of peroxisomal membrane(GO:0005779)
0.0 0.3 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.3 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 0.3 GO:0042555 MCM complex(GO:0042555)
0.0 0.2 GO:0061617 MICOS complex(GO:0061617)
0.0 0.1 GO:0005594 collagen type IX trimer(GO:0005594)
0.0 0.6 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.2 GO:0044613 nuclear pore central transport channel(GO:0044613)
0.0 0.5 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.1 GO:1990452 Parkin-FBXW7-Cul1 ubiquitin ligase complex(GO:1990452)
0.0 1.0 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 1.5 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.1 GO:0005851 eukaryotic translation initiation factor 2B complex(GO:0005851)
0.0 0.2 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.0 0.2 GO:0030897 HOPS complex(GO:0030897)
0.0 0.1 GO:0036396 MIS complex(GO:0036396)
0.0 0.4 GO:0031307 integral component of mitochondrial outer membrane(GO:0031307)
0.0 0.5 GO:0071011 precatalytic spliceosome(GO:0071011)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 3.2 GO:0061731 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.2 0.7 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.1 0.5 GO:0004466 long-chain-acyl-CoA dehydrogenase activity(GO:0004466)
0.1 0.4 GO:1990698 palmitoleoyltransferase activity(GO:1990698)
0.1 0.5 GO:0016882 cyclo-ligase activity(GO:0016882)
0.1 0.4 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.1 1.5 GO:0008097 5S rRNA binding(GO:0008097)
0.1 0.2 GO:0000405 bubble DNA binding(GO:0000405)
0.1 0.6 GO:0005324 long-chain fatty acid transporter activity(GO:0005324)
0.1 0.6 GO:0071074 eukaryotic initiation factor eIF2 binding(GO:0071074)
0.1 0.3 GO:0015410 manganese-transporting ATPase activity(GO:0015410)
0.1 0.2 GO:0008184 glycogen phosphorylase activity(GO:0008184)
0.1 0.5 GO:0045545 syndecan binding(GO:0045545)
0.1 0.7 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.1 0.7 GO:0098505 G-rich strand telomeric DNA binding(GO:0098505)
0.0 0.2 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.0 0.8 GO:0070403 NAD+ binding(GO:0070403)
0.0 0.7 GO:0043138 3'-5' DNA helicase activity(GO:0043138)
0.0 0.6 GO:0000014 single-stranded DNA endodeoxyribonuclease activity(GO:0000014)
0.0 0.2 GO:0016748 succinyltransferase activity(GO:0016748)
0.0 0.3 GO:0015450 P-P-bond-hydrolysis-driven protein transmembrane transporter activity(GO:0015450)
0.0 0.2 GO:0016802 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.6 GO:0001013 RNA polymerase I regulatory region DNA binding(GO:0001013)
0.0 1.0 GO:0050136 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.1 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.1 GO:0032142 dinucleotide insertion or deletion binding(GO:0032139) single guanine insertion binding(GO:0032142)
0.0 0.1 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.0 0.2 GO:0015563 uptake transmembrane transporter activity(GO:0015563)
0.0 0.2 GO:0008479 queuine tRNA-ribosyltransferase activity(GO:0008479)
0.0 0.2 GO:0015181 arginine transmembrane transporter activity(GO:0015181)
0.0 0.4 GO:0003988 acetyl-CoA C-acyltransferase activity(GO:0003988)
0.0 0.5 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.0 0.2 GO:0047184 1-acylglycerophosphocholine O-acyltransferase activity(GO:0047184)
0.0 0.4 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.0 1.0 GO:0031369 translation initiation factor binding(GO:0031369)
0.0 0.2 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.0 0.4 GO:0051864 histone demethylase activity (H3-K36 specific)(GO:0051864)
0.0 0.1 GO:0003989 acetyl-CoA carboxylase activity(GO:0003989)
0.0 0.1 GO:0045030 UTP-activated nucleotide receptor activity(GO:0045030)
0.0 0.1 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.1 GO:0047874 dolichyldiphosphatase activity(GO:0047874)
0.0 0.1 GO:0004534 5'-3' exoribonuclease activity(GO:0004534)
0.0 0.5 GO:0003678 DNA helicase activity(GO:0003678)
0.0 0.4 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 4.6 PID E2F PATHWAY E2F transcription factor network
0.0 0.9 PID S1P META PATHWAY Sphingosine 1-phosphate (S1P) pathway
0.0 1.1 PID ATR PATHWAY ATR signaling pathway
0.0 0.7 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.5 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.1 1.0 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.1 0.7 REACTOME REMOVAL OF THE FLAP INTERMEDIATE FROM THE C STRAND Genes involved in Removal of the Flap Intermediate from the C-strand
0.0 0.5 REACTOME MRNA DECAY BY 3 TO 5 EXORIBONUCLEASE Genes involved in mRNA Decay by 3' to 5' Exoribonuclease
0.0 1.5 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 0.5 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.2 REACTOME REPAIR SYNTHESIS FOR GAP FILLING BY DNA POL IN TC NER Genes involved in Repair synthesis for gap-filling by DNA polymerase in TC-NER
0.0 0.5 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 0.5 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 0.6 REACTOME ABCA TRANSPORTERS IN LIPID HOMEOSTASIS Genes involved in ABCA transporters in lipid homeostasis
0.0 0.5 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 0.4 REACTOME ACTIVATED AMPK STIMULATES FATTY ACID OXIDATION IN MUSCLE Genes involved in Activated AMPK stimulates fatty-acid oxidation in muscle
0.0 0.3 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.3 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 2.6 REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.0 0.7 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0 0.7 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.3 REACTOME FORMATION OF TRANSCRIPTION COUPLED NER TC NER REPAIR COMPLEX Genes involved in Formation of transcription-coupled NER (TC-NER) repair complex
0.0 0.7 REACTOME TRANSLATION Genes involved in Translation
0.0 0.7 REACTOME CDK MEDIATED PHOSPHORYLATION AND REMOVAL OF CDC6 Genes involved in CDK-mediated phosphorylation and removal of Cdc6
0.0 0.2 REACTOME GLYCOGEN BREAKDOWN GLYCOGENOLYSIS Genes involved in Glycogen breakdown (glycogenolysis)
0.0 0.1 REACTOME E2F ENABLED INHIBITION OF PRE REPLICATION COMPLEX FORMATION Genes involved in E2F-enabled inhibition of pre-replication complex formation