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avrg: GFI1 WT vs 36n/n vs KD

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Results for E2f4

Z-value: 0.67

Motif logo

Transcription factors associated with E2f4

Gene Symbol Gene ID Gene Info
ENSMUSG00000014859.10 E2F transcription factor 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
E2f4mm39_v1_chr8_+_106024294_106024367-0.968.1e-03Click!

Activity profile of E2f4 motif

Sorted Z-values of E2f4 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr4_-_133694607 0.49 ENSMUST00000105893.8
high mobility group nucleosomal binding domain 2
chr12_+_24758240 0.41 ENSMUST00000020980.12
ribonucleotide reductase M2
chr4_+_134238310 0.40 ENSMUST00000105866.3
aurora kinase A and ninein interacting protein
chr6_-_56681657 0.35 ENSMUST00000176595.3
ENSMUST00000170382.5
ENSMUST00000203958.2
LSM5 homolog, U6 small nuclear RNA and mRNA degradation associated
chrX_+_37689503 0.31 ENSMUST00000000365.3
malignant T cell amplified sequence 1
chr1_-_72251466 0.31 ENSMUST00000048860.9
melanoregulin
chr1_-_10108325 0.31 ENSMUST00000027050.10
ENSMUST00000188619.2
COP9 signalosome subunit 5
chr10_+_87982916 0.29 ENSMUST00000169309.3
nucleoporin 37
chr5_+_21577640 0.29 ENSMUST00000035799.6
fibrinogen-like protein 2
chr10_+_87982854 0.28 ENSMUST00000052355.15
nucleoporin 37
chr17_+_85264134 0.28 ENSMUST00000112305.10
protein phosphatase 1B, magnesium dependent, beta isoform
chr4_-_133694543 0.28 ENSMUST00000123234.8
high mobility group nucleosomal binding domain 2
chr11_+_68936457 0.28 ENSMUST00000108666.8
ENSMUST00000021277.6
aurora kinase B
chr4_-_132072988 0.27 ENSMUST00000030726.13
regulator of chromosome condensation 1
chr8_+_108271643 0.26 ENSMUST00000212543.2
WW domain containing E3 ubiquitin protein ligase 2
chr1_+_57416752 0.26 ENSMUST00000042734.3
RIKEN cDNA 1700066M21 gene
chr3_-_107876477 0.26 ENSMUST00000004136.10
glutathione S-transferase, mu 3
chr4_-_132073048 0.26 ENSMUST00000084250.11
regulator of chromosome condensation 1
chr9_+_107828136 0.25 ENSMUST00000049348.9
ENSMUST00000194271.2
TRAF-interacting protein
chr11_+_95557783 0.24 ENSMUST00000125172.8
ENSMUST00000036374.6
prohibitin
chr19_+_6135013 0.24 ENSMUST00000025704.3
cell division cycle associated 5
chr4_-_133695264 0.24 ENSMUST00000102553.11
high mobility group nucleosomal binding domain 2
chr4_-_133695204 0.24 ENSMUST00000100472.10
ENSMUST00000136327.2
high mobility group nucleosomal binding domain 2
chrX_+_12454031 0.23 ENSMUST00000033313.3
ATPase, H+ transporting, lysosomal accessory protein 2
chr17_-_66408461 0.22 ENSMUST00000024909.15
ENSMUST00000147484.2
NADH:ubiquinone oxidoreductase core subunit V2
chr1_-_169359015 0.22 ENSMUST00000111368.8
NUF2, NDC80 kinetochore complex component
chr4_-_3835595 0.22 ENSMUST00000138502.2
ribosomal protein S20
chr9_+_106354463 0.21 ENSMUST00000047721.10
ribosomal RNA processing 9, U3 small nucleolar RNA binding protein
chr2_+_125994050 0.21 ENSMUST00000170908.8
DTW domain containing 1
chr19_-_7460550 0.20 ENSMUST00000088169.7
reticulon 3
chr5_-_138170077 0.20 ENSMUST00000155902.8
ENSMUST00000148879.8
minichromosome maintenance complex component 7
chr2_-_3513783 0.20 ENSMUST00000124331.8
ENSMUST00000140494.2
ENSMUST00000027961.12
predicted gene 45902
heat shock protein 14
chr5_-_92496730 0.20 ENSMUST00000038816.13
ENSMUST00000118006.3
chemokine (C-X-C motif) ligand 10
chr15_-_98729333 0.20 ENSMUST00000168846.3
protein kinase, AMP-activated, gamma 1 non-catalytic subunit
chr12_-_87194658 0.19 ENSMUST00000037788.6
protein-O-mannosyltransferase 2
chrX_+_163763588 0.18 ENSMUST00000167446.8
ENSMUST00000057150.8
Fanconi anemia, complementation group B
chr11_+_108811168 0.18 ENSMUST00000052915.14
axin 2
chr11_+_108316018 0.18 ENSMUST00000150863.9
ENSMUST00000061287.12
ENSMUST00000149683.9
centrosomal protein 112
chr9_-_103243039 0.17 ENSMUST00000035484.11
carnitine deficiency-associated gene expressed in ventricle 3
chr2_+_71617402 0.17 ENSMUST00000238991.2
integrin alpha 6
chr2_+_71617266 0.17 ENSMUST00000112101.8
ENSMUST00000028522.10
integrin alpha 6
chr9_+_120762884 0.16 ENSMUST00000145093.2
catenin (cadherin associated protein), beta 1
chr11_+_120675083 0.16 ENSMUST00000100134.10
ENSMUST00000208737.2
G protein pathway suppressor 1
chr11_-_51579441 0.16 ENSMUST00000007921.9
RIKEN cDNA 0610009B22 gene
chr11_-_5492175 0.16 ENSMUST00000020776.5
coiled-coil domain containing 117
chr17_-_25946370 0.16 ENSMUST00000170070.3
ENSMUST00000048054.14
CTF18, chromosome transmission fidelity factor 18
chr1_+_85822250 0.15 ENSMUST00000185569.2
integral membrane protein 2C
chr1_-_169358912 0.15 ENSMUST00000192248.2
ENSMUST00000028000.13
NUF2, NDC80 kinetochore complex component
chr9_-_82857528 0.15 ENSMUST00000034787.12
pleckstrin homology domain interacting protein
chr19_-_7460600 0.15 ENSMUST00000235593.2
ENSMUST00000088171.12
ENSMUST00000065304.13
ENSMUST00000025667.14
reticulon 3
chrX_+_161684221 0.14 ENSMUST00000101095.9
cytidine 5'-triphosphate synthase 2
chr18_-_34884555 0.14 ENSMUST00000060710.9
cell division cycle 25C
chr4_+_135583018 0.14 ENSMUST00000105853.10
ENSMUST00000097844.9
ENSMUST00000102544.9
ENSMUST00000126641.2
serine and arginine-rich splicing factor 10
chr8_+_124750133 0.14 ENSMUST00000034457.9
URB2 ribosome biogenesis 2 homolog (S. cerevisiae)
chr10_-_87982732 0.14 ENSMUST00000164121.8
ENSMUST00000164803.2
ENSMUST00000168163.8
ENSMUST00000048518.16
PARP1 binding protein
chrX_-_163763273 0.14 ENSMUST00000112247.9
ENSMUST00000004715.2
motile sperm domain containing 2
chr14_+_76725876 0.13 ENSMUST00000101618.9
TSC22 domain family, member 1
chr6_+_124807176 0.13 ENSMUST00000131847.8
ENSMUST00000151674.3
cell division cycle associated 3
chr17_-_35265702 0.13 ENSMUST00000097338.11
mutS homolog 5
chrX_+_141464393 0.13 ENSMUST00000112889.8
ENSMUST00000101198.9
ENSMUST00000112891.8
ENSMUST00000087333.9
transmembrane protein 164
chr5_+_130285870 0.13 ENSMUST00000100662.10
ENSMUST00000040213.13
tRNA-yW synthesizing protein 1 homolog (S. cerevisiae)
chr3_-_62414391 0.13 ENSMUST00000029336.6
DEAH (Asp-Glu-Ala-His) box polypeptide 36
chr4_+_44004437 0.12 ENSMUST00000107846.10
clathrin, light polypeptide (Lca)
chr10_+_36850532 0.12 ENSMUST00000019911.14
ENSMUST00000105510.2
histone deacetylase 2
chr1_+_9868332 0.12 ENSMUST00000166384.8
ENSMUST00000168907.8
serum/glucocorticoid regulated kinase 3
chr12_+_105976463 0.12 ENSMUST00000072040.7
vaccinia related kinase 1
chr15_-_10714653 0.12 ENSMUST00000169385.3
retinoic acid induced 14
chr11_-_106890307 0.12 ENSMUST00000018506.13
karyopherin (importin) alpha 2
chr14_+_55815580 0.11 ENSMUST00000174484.8
proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
chr12_+_117807607 0.11 ENSMUST00000176735.8
ENSMUST00000177339.2
cell division cycle associated 7 like
chr15_-_39807359 0.11 ENSMUST00000110305.3
low density lipoprotein-related protein 12
chr12_-_118162652 0.11 ENSMUST00000084806.7
dynein, axonemal, heavy chain 11
chr2_+_162896602 0.11 ENSMUST00000018005.10
myeloblastosis oncogene-like 2
chr4_-_115980813 0.11 ENSMUST00000102704.4
ENSMUST00000102705.10
RAD54 like (S. cerevisiae)
chr19_+_8713156 0.11 ENSMUST00000210512.2
ENSMUST00000049424.11
WD repeat domain 74
chr19_+_5416769 0.11 ENSMUST00000025759.9
eukaryotic translation initiation factor 1A domain containing
chr1_+_92862432 0.11 ENSMUST00000117814.8
calpain 10
chr18_+_65933586 0.10 ENSMUST00000025394.14
ENSMUST00000236847.2
ENSMUST00000153193.3
SEC11 homolog C, signal peptidase complex subunit
chr8_-_11600689 0.10 ENSMUST00000049461.7
cysteinyl-tRNA synthetase 2 (mitochondrial)(putative)
chr18_+_56840813 0.10 ENSMUST00000025486.9
lamin B1
chr19_+_45991907 0.10 ENSMUST00000099393.4
HPS6, biogenesis of lysosomal organelles complex 2 subunit 3
chrX_-_165992145 0.10 ENSMUST00000112176.8
thymosin, beta 4, X chromosome
chr19_+_6451667 0.10 ENSMUST00000113471.3
ENSMUST00000113469.3
RAS, guanyl releasing protein 2
chr17_+_35219998 0.10 ENSMUST00000173584.8
valyl-tRNA synthetase
chr7_-_37806912 0.10 ENSMUST00000108023.10
cyclin E1
chr3_-_142587419 0.09 ENSMUST00000174422.8
ENSMUST00000173830.8
protein kinase N2
chr4_+_108691798 0.09 ENSMUST00000030296.9
thioredoxin domain containing 12 (endoplasmic reticulum)
chr5_-_138170644 0.09 ENSMUST00000000505.16
minichromosome maintenance complex component 7
chr2_+_180961507 0.09 ENSMUST00000098971.11
ENSMUST00000054622.15
ENSMUST00000108814.8
ENSMUST00000048608.16
ENSMUST00000108815.8
regulator of telomere elongation helicase 1
chr5_+_123214332 0.09 ENSMUST00000067505.15
ENSMUST00000111619.10
ENSMUST00000160344.2
transmembrane protein 120B
chr4_-_59783780 0.09 ENSMUST00000107526.8
ENSMUST00000095063.11
INTS3 and NABP interacting protein
chr9_+_44245981 0.08 ENSMUST00000052686.4
H2A.X variant histone
chr13_-_74085880 0.08 ENSMUST00000022053.11
thyroid hormone receptor interactor 13
chr5_-_25910788 0.08 ENSMUST00000030773.12
X-ray repair complementing defective repair in Chinese hamster cells 2
chr8_-_106223502 0.08 ENSMUST00000212303.2
zinc finger, DHHC domain containing 1
chr16_-_59452883 0.08 ENSMUST00000118438.8
ADP-ribosylation factor-like 6
chr11_+_77928736 0.08 ENSMUST00000072289.12
ENSMUST00000100784.9
ENSMUST00000073660.7
flotillin 2
chr12_+_105976533 0.07 ENSMUST00000085026.12
ENSMUST00000021539.16
vaccinia related kinase 1
chr9_+_57615816 0.07 ENSMUST00000043990.14
ENSMUST00000142807.2
enhancer of mRNA decapping 3
chr17_+_35219941 0.07 ENSMUST00000087315.14
valyl-tRNA synthetase
chr3_+_88461059 0.07 ENSMUST00000008748.8
ubiquilin 4
chr1_-_157240138 0.07 ENSMUST00000078308.13
RAS protein activator like 2
chr9_-_60595401 0.07 ENSMUST00000114034.9
ENSMUST00000065603.12
leucine rich repeat containing 49
chr17_-_66408543 0.07 ENSMUST00000143987.9
NADH:ubiquinone oxidoreductase core subunit V2
chr3_-_116456292 0.07 ENSMUST00000029570.9
major facilitator superfamily domain containing 14A
chr11_-_101442663 0.07 ENSMUST00000017290.11
breast cancer 1, early onset
chr11_+_101443014 0.07 ENSMUST00000147239.8
NBR1, autophagy cargo receptor
chr9_-_103242737 0.06 ENSMUST00000072249.13
ENSMUST00000189896.2
carnitine deficiency-associated gene expressed in ventricle 3
chr11_+_29080733 0.06 ENSMUST00000020756.9
polyribonucleotide nucleotidyltransferase 1
chrX_+_104123341 0.06 ENSMUST00000033577.11
polysaccharide biosynthesis domain containing 1
chr5_+_138170259 0.06 ENSMUST00000019662.11
ENSMUST00000151318.8
adaptor-related protein complex AP-4, mu 1
chr10_-_90959853 0.06 ENSMUST00000170810.8
ENSMUST00000076694.13
solute carrier family 25 (mitochondrial carrier, phosphate carrier), member 3
chrX_+_161684563 0.06 ENSMUST00000112303.8
ENSMUST00000033727.14
cytidine 5'-triphosphate synthase 2
chr9_-_83323080 0.06 ENSMUST00000034791.15
ENSMUST00000188548.7
ENSMUST00000034793.15
Leber congenital amaurosis 5 (human)
chr8_-_54091980 0.06 ENSMUST00000047768.11
nei like 3 (E. coli)
chr2_-_145776934 0.06 ENSMUST00000001818.5
crooked neck pre-mRNA splicing factor 1
chr6_-_113508536 0.05 ENSMUST00000032425.7
ER membrane protein complex subunit 3
chr7_+_126808016 0.05 ENSMUST00000206204.2
ENSMUST00000206772.2
myosin light chain, phosphorylatable, fast skeletal muscle
chr3_+_89680867 0.05 ENSMUST00000038356.13
ubiquitin-conjugating enzyme E2Q family member 1
chrX_+_104123367 0.05 ENSMUST00000119477.2
polysaccharide biosynthesis domain containing 1
chr3_-_142587678 0.05 ENSMUST00000043812.15
protein kinase N2
chrX_+_161684735 0.05 ENSMUST00000112302.8
ENSMUST00000112301.8
cytidine 5'-triphosphate synthase 2
chr1_-_179631190 0.05 ENSMUST00000027768.14
AT hook containing transcription factor 1
chr2_+_180961599 0.05 ENSMUST00000153112.2
regulator of telomere elongation helicase 1
chr7_+_24584076 0.04 ENSMUST00000153451.9
ENSMUST00000108429.8
ribosomal protein S19
chr11_+_108811626 0.04 ENSMUST00000140821.2
axin 2
chr2_-_52566583 0.04 ENSMUST00000178799.8
calcium channel, voltage-dependent, beta 4 subunit
chr17_+_31514780 0.04 ENSMUST00000237460.2
solute carrier family 37 (glycerol-3-phosphate transporter), member 1
chr5_-_33809640 0.04 ENSMUST00000151081.2
ENSMUST00000139518.8
ENSMUST00000101354.10
stem-loop binding protein
chr17_+_31515163 0.03 ENSMUST00000235972.2
ENSMUST00000165149.3
ENSMUST00000236251.2
solute carrier family 37 (glycerol-3-phosphate transporter), member 1
chr12_+_99850756 0.03 ENSMUST00000153627.8
tyrosyl-DNA phosphodiesterase 1
chr2_-_30176324 0.03 ENSMUST00000100219.5
dolichol kinase
chr11_-_106890195 0.03 ENSMUST00000106768.2
ENSMUST00000144834.8
karyopherin (importin) alpha 2
chr13_-_14237958 0.03 ENSMUST00000223174.2
geranylgeranyl diphosphate synthase 1
chr17_+_25946644 0.03 ENSMUST00000237183.2
ENSMUST00000237785.2
ENSMUST00000047273.3
RNA pseudouridylate synthase domain containing 1
chr2_-_62476487 0.03 ENSMUST00000112459.4
ENSMUST00000028259.12
interferon induced with helicase C domain 1
chr5_-_33809872 0.03 ENSMUST00000057551.14
stem-loop binding protein
chrX_-_163763337 0.02 ENSMUST00000112248.9
motile sperm domain containing 2
chr4_+_43059028 0.02 ENSMUST00000163653.8
ENSMUST00000107952.9
ENSMUST00000107953.9
unc-13 homolog B
chr7_-_97228589 0.02 ENSMUST00000151840.2
ENSMUST00000135998.8
ENSMUST00000144858.8
ENSMUST00000146605.8
ENSMUST00000072725.12
ENSMUST00000138060.3
ENSMUST00000154853.8
ENSMUST00000136757.8
ENSMUST00000124552.3
adipogenesis associated Mth938 domain containing
chr12_-_4283926 0.02 ENSMUST00000111169.10
ENSMUST00000020981.12
centromere protein O
chr16_-_90524214 0.02 ENSMUST00000099554.5
MIS18 kinetochore protein A
chr7_-_92523396 0.02 ENSMUST00000209074.2
ENSMUST00000208356.2
ENSMUST00000032877.11
DNA damage-induced apoptosis suppressor
chr14_-_54754810 0.02 ENSMUST00000023873.12
protein arginine N-methyltransferase 5
chr6_-_148732893 0.02 ENSMUST00000145960.2
importin 8
chr4_+_11558905 0.02 ENSMUST00000095145.12
ENSMUST00000108306.9
ENSMUST00000070755.13
RAD54 homolog B (S. cerevisiae)
chr7_-_81104423 0.02 ENSMUST00000178892.3
ENSMUST00000098331.10
cytoplasmic polyadenylation element binding protein 1
chr19_+_4771089 0.02 ENSMUST00000238976.3
spectrin beta, non-erythrocytic 2
chr6_+_113508636 0.02 ENSMUST00000036340.12
ENSMUST00000204827.3
Fanconi anemia, complementation group D2
chr2_+_24257576 0.02 ENSMUST00000140547.2
ENSMUST00000102942.8
pleckstrin and Sec7 domain containing 4
chr15_-_37792635 0.01 ENSMUST00000090150.11
ENSMUST00000150453.2
neurocalcin delta
chr9_-_123507847 0.01 ENSMUST00000170591.2
ENSMUST00000171647.9
solute carrier family 6 (neurotransmitter transporter), member 20A
chr7_+_45433103 0.01 ENSMUST00000209617.2
ENSMUST00000209701.2
lemur tyrosine kinase 3
chr15_-_37792237 0.01 ENSMUST00000168992.8
ENSMUST00000148652.9
neurocalcin delta
chr11_+_74510413 0.01 ENSMUST00000100866.3
coiled-coil domain containing 92B
chr7_+_97020810 0.01 ENSMUST00000098300.6
asparagine-linked glycosylation 8 (alpha-1,3-glucosyltransferase)
chr7_-_126859790 0.01 ENSMUST00000035276.5
dCTP pyrophosphatase 1
chr3_+_87704258 0.01 ENSMUST00000029711.9
ENSMUST00000107582.3
insulin receptor-related receptor
chr17_+_35220252 0.01 ENSMUST00000174260.8
valyl-tRNA synthetase
chrY_-_90850446 0.01 ENSMUST00000179623.2
predicted gene, 21748
chr2_-_63014514 0.01 ENSMUST00000112452.2
potassium voltage-gated channel, subfamily H (eag-related), member 7
chr14_+_70793340 0.01 ENSMUST00000163060.2
lysine demethylase and nuclear receptor corepressor
chr1_+_52669849 0.01 ENSMUST00000165859.8
nuclear envelope integral membrane protein 2
chr2_+_101508747 0.01 ENSMUST00000004949.8
TNF receptor-associated factor 6
chr17_+_88748139 0.01 ENSMUST00000112238.9
ENSMUST00000155640.2
forkhead box N2
chr13_-_41264511 0.01 ENSMUST00000225271.2
glial cells missing homolog 2
chr5_+_30437579 0.01 ENSMUST00000145167.9
selenoprotein I
chr2_+_106525938 0.01 ENSMUST00000016530.14
metallophosphoesterase domain containing 2
chr12_-_104120105 0.01 ENSMUST00000085050.4
serine (or cysteine) peptidase inhibitor, clade A, member 3C
chr7_+_45433306 0.01 ENSMUST00000072580.12
lemur tyrosine kinase 3
chr18_-_58343423 0.01 ENSMUST00000025497.8
fibrillin 2
chr11_+_16901370 0.01 ENSMUST00000109635.2
ENSMUST00000061327.2
F-box protein 48
chr19_+_46064302 0.01 ENSMUST00000165017.2
ENSMUST00000223741.2
ENSMUST00000225780.2
nucleolar and coiled-body phosphoprotein 1
chr3_-_6685492 0.01 ENSMUST00000091364.4
RIKEN cDNA 1700008P02 gene
chr4_+_43562706 0.00 ENSMUST00000167751.2
ENSMUST00000132631.2
cAMP responsive element binding protein 3
chr8_-_123884968 0.00 ENSMUST00000137998.2
sulfotransferase family 5A, member 1
chr5_-_108697857 0.00 ENSMUST00000129040.2
ENSMUST00000046892.10
complexin 1
chr4_-_44704006 0.00 ENSMUST00000146335.8
paired box 5
chr4_-_58553171 0.00 ENSMUST00000145361.2
lysophosphatidic acid receptor 1
chr8_-_107783282 0.00 ENSMUST00000034391.4
ENSMUST00000095517.12
component of oligomeric golgi complex 8
chr14_+_33073249 0.00 ENSMUST00000140711.3
Rho GTPase activating protein 22
chr10_+_12936248 0.00 ENSMUST00000193426.6
pleiomorphic adenoma gene-like 1
chr2_+_163046394 0.00 ENSMUST00000128999.8
TOX high mobility group box family member 2
chr1_-_33708876 0.00 ENSMUST00000027312.11
DNA primase, p58 subunit

Network of associatons between targets according to the STRING database.

First level regulatory network of E2f4

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0043988 histone H3-S28 phosphorylation(GO:0043988)
0.1 0.2 GO:1905168 positive regulation of double-strand break repair via homologous recombination(GO:1905168)
0.1 0.2 GO:1904499 regulation of chromatin-mediated maintenance of transcription(GO:1904499) positive regulation of chromatin-mediated maintenance of transcription(GO:1904501) regulation of euchromatin binding(GO:1904793)
0.1 0.3 GO:0002188 translation reinitiation(GO:0002188)
0.0 0.2 GO:1901740 negative regulation of myoblast fusion(GO:1901740)
0.0 0.2 GO:2000259 positive regulation of complement activation(GO:0045917) positive regulation of protein activation cascade(GO:2000259)
0.0 0.2 GO:0071921 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.0 0.2 GO:0072355 histone H3-T3 phosphorylation(GO:0072355)
0.0 0.2 GO:0070602 regulation of centromeric sister chromatid cohesion(GO:0070602)
0.0 0.3 GO:0006499 N-terminal protein myristoylation(GO:0006499)
0.0 0.1 GO:0061198 fungiform papilla formation(GO:0061198)
0.0 0.4 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.0 0.2 GO:0002003 angiotensin maturation(GO:0002003)
0.0 1.2 GO:0040034 regulation of development, heterochronic(GO:0040034)
0.0 0.1 GO:1902990 mitotic telomere maintenance via semi-conservative replication(GO:1902990) negative regulation of t-circle formation(GO:1904430)
0.0 0.3 GO:0035878 nail development(GO:0035878)
0.0 0.2 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
0.0 0.3 GO:1903894 regulation of IRE1-mediated unfolded protein response(GO:1903894)
0.0 0.2 GO:1904098 regulation of protein O-linked glycosylation(GO:1904098) positive regulation of protein O-linked glycosylation(GO:1904100)
0.0 0.1 GO:0090669 telomerase RNA stabilization(GO:0090669)
0.0 0.1 GO:1904008 regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031660) positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in G2/M transition of mitotic cell cycle(GO:0031662) response to monosodium glutamate(GO:1904008) cellular response to monosodium glutamate(GO:1904009)
0.0 0.3 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.0 0.9 GO:0051290 protein heterotetramerization(GO:0051290)
0.0 0.1 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.0 0.1 GO:0035928 rRNA import into mitochondrion(GO:0035928)
0.0 0.2 GO:0042985 negative regulation of amyloid precursor protein biosynthetic process(GO:0042985)
0.0 0.2 GO:1900262 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.0 0.3 GO:0010804 negative regulation of tumor necrosis factor-mediated signaling pathway(GO:0010804)
0.0 0.2 GO:0006241 CTP biosynthetic process(GO:0006241) CTP metabolic process(GO:0046036)
0.0 0.1 GO:0046909 intermembrane transport(GO:0046909) protein transport from ciliary membrane to plasma membrane(GO:1903445)
0.0 0.1 GO:2000042 negative regulation of double-strand break repair via homologous recombination(GO:2000042)
0.0 0.3 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.1 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
0.0 0.1 GO:1903903 protein localization to plasma membrane raft(GO:0044860) regulation of establishment of T cell polarity(GO:1903903)
0.0 0.3 GO:0042640 anagen(GO:0042640)
0.0 0.0 GO:0060265 positive regulation of respiratory burst involved in inflammatory response(GO:0060265)
0.0 0.1 GO:0003352 regulation of cilium movement(GO:0003352) regulation of cilium beat frequency(GO:0003356)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0005971 ribonucleoside-diphosphate reductase complex(GO:0005971)
0.1 0.4 GO:0031262 Ndc80 complex(GO:0031262)
0.0 0.3 GO:0032133 chromosome passenger complex(GO:0032133)
0.0 0.6 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.1 GO:0098843 postsynaptic endocytic zone(GO:0098843)
0.0 0.2 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.0 0.1 GO:0031084 BLOC-2 complex(GO:0031084)
0.0 0.2 GO:0008278 cohesin complex(GO:0008278)
0.0 0.2 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.0 0.1 GO:0008537 proteasome activator complex(GO:0008537)
0.0 0.2 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.0 0.1 GO:0031523 Myb complex(GO:0031523)
0.0 0.2 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.0 0.1 GO:0005638 lamin filament(GO:0005638)
0.0 0.1 GO:0070876 SOSS complex(GO:0070876)
0.0 0.2 GO:0042555 MCM complex(GO:0042555)
0.0 0.1 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.0 0.3 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.1 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.1 GO:0033063 Rad51B-Rad51C-Rad51D-XRCC2 complex(GO:0033063)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.1 0.5 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.1 0.4 GO:0016728 ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor(GO:0004748) oxidoreductase activity, acting on CH or CH2 groups, disulfide as acceptor(GO:0016728) ribonucleoside-diphosphate reductase activity(GO:0061731)
0.1 0.2 GO:0035175 histone kinase activity (H3-S10 specific)(GO:0035175)
0.1 0.2 GO:0003883 CTP synthase activity(GO:0003883)
0.0 0.1 GO:0035851 Krueppel-associated box domain binding(GO:0035851)
0.0 0.2 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.0 0.3 GO:0038132 neuregulin binding(GO:0038132)
0.0 0.1 GO:0019153 protein-disulfide reductase (glutathione) activity(GO:0019153)
0.0 0.2 GO:0004832 valine-tRNA ligase activity(GO:0004832)
0.0 0.2 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.2 GO:0004679 AMP-activated protein kinase activity(GO:0004679)
0.0 0.2 GO:0034511 U3 snoRNA binding(GO:0034511)
0.0 0.4 GO:0070411 I-SMAD binding(GO:0070411)
0.0 0.3 GO:0035174 histone serine kinase activity(GO:0035174)
0.0 0.2 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.1 GO:0000405 bubble DNA binding(GO:0000405)
0.0 0.1 GO:0036310 annealing helicase activity(GO:0036310)
0.0 0.4 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.1 GO:0051880 G-quadruplex DNA binding(GO:0051880)
0.0 0.1 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.1 GO:0015526 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 PID INTEGRIN4 PATHWAY Alpha6 beta4 integrin-ligand interactions
0.0 0.3 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.4 PID BETA CATENIN DEG PATHWAY Degradation of beta catenin

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 REACTOME G1 S SPECIFIC TRANSCRIPTION Genes involved in G1/S-Specific Transcription
0.0 0.3 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 0.2 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.1 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.0 0.4 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0 0.3 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.3 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GLP1 Genes involved in Synthesis, Secretion, and Inactivation of Glucagon-like Peptide-1 (GLP-1)