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avrg: GFI1 WT vs 36n/n vs KD

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Results for Egr1

Z-value: 0.74

Motif logo

Transcription factors associated with Egr1

Gene Symbol Gene ID Gene Info
ENSMUSG00000038418.8 early growth response 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Egr1mm39_v1_chr18_+_34994253_349942680.593.0e-01Click!

Activity profile of Egr1 motif

Sorted Z-values of Egr1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr13_+_21938258 0.65 ENSMUST00000091709.3
H2B clustered histone 15
chrX_-_20787150 0.49 ENSMUST00000081893.7
ENSMUST00000115345.8
synapsin I
chr13_+_23715220 0.47 ENSMUST00000102972.6
H4 clustered histone 8
chr6_+_122803624 0.45 ENSMUST00000203075.2
forkhead box J2
chr2_+_117942357 0.42 ENSMUST00000039559.9
thrombospondin 1
chr4_+_42949814 0.40 ENSMUST00000037872.10
ENSMUST00000098112.9
DnaJ heat shock protein family (Hsp40) member B5
chr8_+_73072877 0.39 ENSMUST00000067912.8
Kruppel-like factor 2 (lung)
chr6_-_52211882 0.37 ENSMUST00000125581.2
homeobox A10
chr5_-_107873883 0.29 ENSMUST00000159263.3
growth factor independent 1 transcription repressor
chr2_-_34262012 0.28 ENSMUST00000113132.9
ENSMUST00000040638.15
pre B cell leukemia homeobox 3
chr11_+_118913788 0.24 ENSMUST00000026662.8
chromobox 2
chr10_+_79977291 0.24 ENSMUST00000105367.8
ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit
chr1_-_36978602 0.23 ENSMUST00000027290.12
transmembrane protein 131
chr2_+_32425327 0.23 ENSMUST00000133512.2
ENSMUST00000048375.6
family with sequence similarity 102, member A
chr11_+_98851238 0.22 ENSMUST00000107473.3
retinoic acid receptor, alpha
chr5_-_142891686 0.21 ENSMUST00000106216.3
actin, beta
chr14_-_33169099 0.21 ENSMUST00000111944.10
ENSMUST00000022504.12
ENSMUST00000111945.9
mitogen-activated protein kinase 8
chr1_-_86286690 0.21 ENSMUST00000185785.2
nucleolin
chr14_+_24540745 0.21 ENSMUST00000112384.10
ribosomal protein S24
chr6_-_124894902 0.21 ENSMUST00000032216.7
parathymosin
chr19_+_37423198 0.20 ENSMUST00000025944.9
hematopoietically expressed homeobox
chr3_-_131196213 0.20 ENSMUST00000197057.2
sphingomyelin synthase 2
chr1_+_39940189 0.19 ENSMUST00000191761.6
ENSMUST00000193682.6
ENSMUST00000195860.6
ENSMUST00000195259.6
ENSMUST00000195636.6
ENSMUST00000192509.6
mitogen-activated protein kinase kinase kinase kinase 4
chr17_-_35340189 0.18 ENSMUST00000025246.13
ENSMUST00000173114.8
casein kinase 2, beta polypeptide
chr14_+_24540815 0.18 ENSMUST00000224568.2
ribosomal protein S24
chr8_-_33374282 0.17 ENSMUST00000209107.4
ENSMUST00000209022.3
neuregulin 1
chr5_-_137015683 0.17 ENSMUST00000034953.14
ENSMUST00000085941.12
zinc finger, HIT domain containing 1
chr5_+_143608194 0.17 ENSMUST00000116456.10
cytohesin 3
chr7_+_26958150 0.17 ENSMUST00000079258.7
numb-like
chr14_+_24540777 0.16 ENSMUST00000169826.3
ENSMUST00000225023.2
ENSMUST00000223999.2
ribosomal protein S24
chr19_+_4264470 0.16 ENSMUST00000237171.2
predicted gene, 45928
chr17_-_35340006 0.15 ENSMUST00000174306.8
ENSMUST00000174024.8
casein kinase 2, beta polypeptide
chr7_-_45071897 0.15 ENSMUST00000210271.2
RuvB-like protein 2
chr3_+_146205864 0.15 ENSMUST00000119130.2
guanine nucleotide binding protein (G protein), gamma 5
chr2_-_27365612 0.15 ENSMUST00000147736.2
bromodomain containing 3
chr4_+_43669266 0.14 ENSMUST00000107864.8
transmembrane protein 8B
chr4_+_42917228 0.14 ENSMUST00000107976.9
ENSMUST00000069184.9
PHD finger protein 24
chr11_-_106679671 0.14 ENSMUST00000123339.2
DEAD box helicase 5
chr18_-_20879461 0.14 ENSMUST00000070080.6
UDP-Gal:betaGlcNAc beta 1,4-galactosyltransferase, polypeptide 6
chr4_-_133856025 0.14 ENSMUST00000105879.2
ENSMUST00000030651.9
SH3 domain binding glutamic acid-rich protein-like 3
chr11_-_4696778 0.14 ENSMUST00000009219.3
calcium binding protein 7
chr17_-_32503060 0.14 ENSMUST00000003726.16
ENSMUST00000121285.8
ENSMUST00000120276.9
bromodomain containing 4
chrX_+_158410229 0.13 ENSMUST00000112456.9
SH3-domain kinase binding protein 1
chr11_+_80191692 0.13 ENSMUST00000017836.8
rhomboid like 3
chr10_-_127502467 0.13 ENSMUST00000099157.4
Ngfi-A binding protein 2
chr9_+_118755521 0.13 ENSMUST00000073109.12
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
chr14_+_76082736 0.13 ENSMUST00000142061.3
tumor protein, translationally-controlled 1
chr16_+_93680783 0.13 ENSMUST00000023666.11
ENSMUST00000117099.8
chromatin assembly factor 1, subunit B (p60)
chr16_+_10363222 0.13 ENSMUST00000155633.8
ENSMUST00000066345.15
C-type lectin domain family 16, member A
chr14_+_34542053 0.13 ENSMUST00000043349.7
glutamate receptor, ionotropic, delta 1
chr16_+_10363203 0.12 ENSMUST00000115824.10
C-type lectin domain family 16, member A
chr6_+_29468067 0.12 ENSMUST00000143101.4
ENSMUST00000149646.3
ATPase, H+ transporting, lysosomal V1 subunit F
chr12_+_108145997 0.12 ENSMUST00000101055.5
cyclin K
chr16_-_18066591 0.12 ENSMUST00000115645.10
RAN binding protein 1
chr10_-_127502541 0.12 ENSMUST00000026469.9
Ngfi-A binding protein 2
chr2_+_164328375 0.12 ENSMUST00000069385.15
ENSMUST00000143690.8
dysbindin (dystrobrevin binding protein 1) domain containing 2
chr5_-_139115417 0.12 ENSMUST00000026973.14
protein kinase, cAMP dependent regulatory, type I beta
chr15_-_66158445 0.11 ENSMUST00000070256.9
potassium voltage-gated channel, subfamily Q, member 3
chr7_-_126102579 0.11 ENSMUST00000040202.15
ataxin 2-like
chr1_+_39940043 0.11 ENSMUST00000168431.7
ENSMUST00000163854.9
mitogen-activated protein kinase kinase kinase kinase 4
chr4_+_40723083 0.11 ENSMUST00000149794.2
DnaJ heat shock protein family (Hsp40) member A1
chr16_+_33504740 0.11 ENSMUST00000232568.2
heart development protein with EGF-like domains 1
chr3_+_146205562 0.11 ENSMUST00000090031.12
ENSMUST00000118280.2
guanine nucleotide binding protein (G protein), gamma 5
chr7_-_126102470 0.11 ENSMUST00000206577.2
ataxin 2-like
chr14_+_76082533 0.11 ENSMUST00000110894.9
tumor protein, translationally-controlled 1
chr1_+_166828982 0.11 ENSMUST00000165874.8
ENSMUST00000190081.7
family with sequence similarity 78, member B
chr8_-_81466126 0.11 ENSMUST00000043359.9
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 5
chr5_+_135717890 0.11 ENSMUST00000005651.13
ENSMUST00000122113.8
P450 (cytochrome) oxidoreductase
chr2_+_27566452 0.10 ENSMUST00000129514.8
retinoid X receptor alpha
chr11_+_115078299 0.10 ENSMUST00000100235.9
ENSMUST00000061450.7
transmembrane protein 104
chr9_+_62746055 0.10 ENSMUST00000034776.13
ceroid-lipofuscinosis, neuronal 6
chr9_+_59658156 0.10 ENSMUST00000136740.8
ENSMUST00000135298.8
ENSMUST00000128341.2
myosin IXa
chr9_-_102231884 0.10 ENSMUST00000035129.14
ENSMUST00000085169.12
ENSMUST00000149800.3
Eph receptor B1
chr7_+_127566629 0.10 ENSMUST00000106251.10
ENSMUST00000077609.12
ENSMUST00000121616.9
fused in sarcoma
chr15_+_78819378 0.10 ENSMUST00000145157.2
ENSMUST00000123013.2
nucleolar protein 12
chr4_-_93223746 0.10 ENSMUST00000066774.6
tumor suppressor candidate 1
chr2_-_167030706 0.10 ENSMUST00000207917.2
potassium voltage gated channel, Shab-related subfamily, member 1
chr17_+_64907697 0.10 ENSMUST00000086723.10
mannosidase 2, alpha 1
chr6_-_124733441 0.10 ENSMUST00000088357.12
atrophin 1
chr18_-_80243812 0.10 ENSMUST00000025462.7
ribosome binding factor A
chr7_+_101619897 0.10 ENSMUST00000211272.2
nuclear mitotic apparatus protein 1
chr19_+_6413703 0.10 ENSMUST00000131252.8
ENSMUST00000113489.8
splicing factor 1
chr11_-_102298281 0.10 ENSMUST00000107098.8
ENSMUST00000018821.9
solute carrier family 25, member 39
chr8_-_123405392 0.10 ENSMUST00000134045.2
CBFA2/RUNX1 translocation partner 3
chr19_+_53588808 0.10 ENSMUST00000025930.10
structural maintenance of chromosomes 3
chr9_-_56325344 0.10 ENSMUST00000061552.15
pseudopodium-enriched atypical kinase 1
chr5_+_137786031 0.09 ENSMUST00000035852.14
zinc finger, CW type with PWWP domain 1
chr15_+_78784043 0.09 ENSMUST00000001226.11
SH3-domain binding protein 1
chr9_-_44145280 0.09 ENSMUST00000205968.2
ENSMUST00000206147.2
ENSMUST00000037644.8
Casitas B-lineage lymphoma
chr17_-_35420972 0.09 ENSMUST00000167924.2
ENSMUST00000025263.15
tumor necrosis factor
chr19_+_5618029 0.09 ENSMUST00000235575.2
ENSMUST00000235542.2
adaptor-related protein complex 5, beta 1 subunit
chr5_-_137016355 0.09 ENSMUST00000137272.2
ENSMUST00000111090.9
zinc finger, HIT domain containing 1
chr19_+_6413840 0.09 ENSMUST00000113488.8
ENSMUST00000113487.8
splicing factor 1
chr11_-_104333059 0.09 ENSMUST00000106977.8
ENSMUST00000106972.8
KAT8 regulatory NSL complex subunit 1
chr1_-_156766351 0.09 ENSMUST00000189648.2
Ral GEF with PH domain and SH3 binding motif 2
chr7_-_126303351 0.09 ENSMUST00000106364.8
coronin, actin binding protein 1A
chr7_-_126303947 0.09 ENSMUST00000032949.14
coronin, actin binding protein 1A
chr9_+_44245981 0.08 ENSMUST00000052686.4
H2A.X variant histone
chr19_+_23736205 0.08 ENSMUST00000025830.9
amyloid beta (A4) precursor protein binding, family A, member 1
chr4_+_118965992 0.08 ENSMUST00000134105.8
ENSMUST00000144329.8
ENSMUST00000208090.2
solute carrier family 2 (facilitated glucose transporter), member 1
chr5_-_34093678 0.08 ENSMUST00000030993.8
negative elongation factor complex member A, Whsc2
chr4_+_86666764 0.08 ENSMUST00000045512.15
ENSMUST00000082026.14
DENN/MADD domain containing 4C
chrX_+_158410528 0.08 ENSMUST00000073094.10
SH3-domain kinase binding protein 1
chr19_+_5618096 0.08 ENSMUST00000096318.4
adaptor-related protein complex 5, beta 1 subunit
chr7_+_3648264 0.08 ENSMUST00000206287.2
ENSMUST00000038913.16
CCR4-NOT transcription complex, subunit 3
chr7_-_80338600 0.08 ENSMUST00000122255.8
CREB regulated transcription coactivator 3
chr8_-_64659004 0.08 ENSMUST00000066166.6
tolloid-like
chr18_-_38068456 0.08 ENSMUST00000080033.7
ENSMUST00000115631.8
ENSMUST00000115634.8
diaphanous related formin 1
chr11_-_115310743 0.08 ENSMUST00000106537.8
ENSMUST00000043931.9
ENSMUST00000073791.10
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit D
chr2_-_122199604 0.08 ENSMUST00000151130.8
Src homology 2 domain containing F
chr11_-_69260203 0.08 ENSMUST00000092971.13
ENSMUST00000108661.8
chromodomain helicase DNA binding protein 3
chr17_-_16046780 0.08 ENSMUST00000232638.2
ENSMUST00000170578.3
repulsive guidance molecule family member B
chr17_-_65920481 0.08 ENSMUST00000024897.10
vesicle-associated membrane protein, associated protein A
chr5_+_65127412 0.08 ENSMUST00000031080.15
family with sequence similarity 114, member A1
chr4_+_128777339 0.08 ENSMUST00000035667.9
tripartite motif-containing 62
chr11_+_68582731 0.08 ENSMUST00000102611.10
myosin, heavy polypeptide 10, non-muscle
chr13_-_58421935 0.08 ENSMUST00000091579.6
G kinase anchoring protein 1
chr2_+_156455583 0.08 ENSMUST00000109567.10
ENSMUST00000169464.9
DLG associated protein 4
chr12_+_108601963 0.08 ENSMUST00000223109.2
Ena-vasodilator stimulated phosphoprotein
chr6_+_99669640 0.08 ENSMUST00000101122.3
G protein-coupled receptor 27
chr10_+_95350975 0.08 ENSMUST00000099329.5
ubiquitin-conjugating enzyme E2N
chr5_+_124583524 0.08 ENSMUST00000100709.7
lysine methyltransferase 5A
chrX_+_7708295 0.08 ENSMUST00000115667.10
ENSMUST00000115668.10
ENSMUST00000115665.2
OTU domain containing 5
chr7_-_24937276 0.08 ENSMUST00000071739.12
ENSMUST00000108411.2
glycogen synthase kinase 3 alpha
chr7_-_16007542 0.07 ENSMUST00000169612.3
InaF motif containing 1
chr3_-_122778052 0.07 ENSMUST00000199401.2
ENSMUST00000197314.5
ENSMUST00000197934.5
ENSMUST00000090379.7
ubiquitin specific peptidase 53
chr6_+_72074545 0.07 ENSMUST00000069994.11
ENSMUST00000114112.4
ST3 beta-galactoside alpha-2,3-sialyltransferase 5
chr14_+_84680993 0.07 ENSMUST00000071370.7
protocadherin 17
chr4_-_22488296 0.07 ENSMUST00000178174.3
POU domain, class 3, transcription factor 2
chr9_+_100956145 0.07 ENSMUST00000189616.2
MSL complex subunit 2
chr11_-_102298141 0.07 ENSMUST00000149777.8
ENSMUST00000154001.8
solute carrier family 25, member 39
chr8_-_11362731 0.07 ENSMUST00000033898.10
collagen, type IV, alpha 1
chr19_+_6291698 0.07 ENSMUST00000045351.13
autophagy related 2A
chr17_+_25946644 0.07 ENSMUST00000237183.2
ENSMUST00000237785.2
ENSMUST00000047273.3
RNA pseudouridylate synthase domain containing 1
chr4_+_3938881 0.07 ENSMUST00000108386.8
ENSMUST00000121110.8
ENSMUST00000149544.8
coiled-coil-helix-coiled-coil-helix domain containing 7
chr1_+_152642291 0.07 ENSMUST00000077755.11
ENSMUST00000097536.6
actin related protein 2/3 complex, subunit 5
chrX_+_55777139 0.07 ENSMUST00000023854.10
ENSMUST00000114769.9
four and a half LIM domains 1
chr16_-_84970580 0.07 ENSMUST00000227737.2
ENSMUST00000226801.2
amyloid beta (A4) precursor protein
chr1_+_60448931 0.07 ENSMUST00000189082.7
ENSMUST00000187709.7
abl interactor 2
chr1_+_134487928 0.07 ENSMUST00000112198.3
lysine (K)-specific demethylase 5B
chr15_-_64184485 0.07 ENSMUST00000177083.8
ENSMUST00000177371.8
ArfGAP with SH3 domain, ankyrin repeat and PH domain1
chr14_-_30075424 0.07 ENSMUST00000224198.3
ENSMUST00000238675.2
ENSMUST00000112249.10
ENSMUST00000224785.3
calcium channel, voltage-dependent, L type, alpha 1D subunit
chr4_-_129590372 0.07 ENSMUST00000137640.3
transmembrane protein 39b
chr14_+_101891416 0.07 ENSMUST00000002289.8
ubiquitin carboxyl-terminal esterase L3 (ubiquitin thiolesterase)
chr9_-_108141105 0.07 ENSMUST00000166905.8
ENSMUST00000191899.6
dystroglycan 1
chr7_+_44667377 0.07 ENSMUST00000044111.10
related RAS viral (r-ras) oncogene
chr10_-_127504416 0.07 ENSMUST00000129252.2
Ngfi-A binding protein 2
chrX_+_7628891 0.07 ENSMUST00000077680.10
ENSMUST00000079542.13
ENSMUST00000115679.8
ENSMUST00000137467.8
transcription factor E3
chr13_-_108026590 0.06 ENSMUST00000225822.4
ENSMUST00000225197.3
zinc finger SWIM-type containing 6
chr10_+_19467697 0.06 ENSMUST00000020188.13
interferon gamma receptor 1
chr13_-_69147639 0.06 ENSMUST00000022013.8
adenylate cyclase 2
chr11_+_97206542 0.06 ENSMUST00000019026.10
ENSMUST00000132168.2
mitochondrial ribosomal protein L45
chr9_-_87613301 0.06 ENSMUST00000034991.8
T-box18
chr4_+_53631460 0.06 ENSMUST00000132151.8
ENSMUST00000159415.9
ENSMUST00000163067.9
fibronectin type III and SPRY domain containing 1-like
chr2_-_104324745 0.06 ENSMUST00000028600.14
homeodomain interacting protein kinase 3
chr13_+_60749735 0.06 ENSMUST00000226059.2
ENSMUST00000077453.13
death associated protein kinase 1
chr9_-_108140925 0.06 ENSMUST00000171412.7
ENSMUST00000195429.6
ENSMUST00000080435.9
dystroglycan 1
chr10_+_79690452 0.06 ENSMUST00000165704.8
polypyrimidine tract binding protein 1
chr8_+_84699580 0.06 ENSMUST00000005606.8
protein kinase, cAMP dependent, catalytic, alpha
chrX_-_52358663 0.06 ENSMUST00000114841.2
ENSMUST00000071023.12
family with sequence similarity 122, member B
chr7_+_24920840 0.06 ENSMUST00000055604.6
zinc finger protein 526
chr2_+_155850002 0.06 ENSMUST00000088650.11
ERGIC and golgi 3
chr17_-_35191127 0.06 ENSMUST00000087328.4
heat shock protein 1A
chr15_-_36609208 0.06 ENSMUST00000001809.15
poly(A) binding protein, cytoplasmic 1
chr7_+_28508220 0.06 ENSMUST00000172529.8
heterogeneous nuclear ribonucleoprotein L
chr13_-_13568106 0.06 ENSMUST00000021738.10
ENSMUST00000220628.2
G protein-coupled receptor 137B
chr14_-_79718890 0.06 ENSMUST00000022601.7
WW domain binding protein 4
chr13_+_83672389 0.06 ENSMUST00000200394.5
myocyte enhancer factor 2C
chr11_+_107438751 0.06 ENSMUST00000100305.8
ENSMUST00000075012.8
ENSMUST00000106746.8
helicase with zinc finger domain
chr16_+_4964849 0.06 ENSMUST00000165810.2
ENSMUST00000230616.2
SEC14-like lipid binding 5
chr2_-_122199643 0.06 ENSMUST00000125826.8
Src homology 2 domain containing F
chr15_+_79231720 0.06 ENSMUST00000096350.11
v-maf musculoaponeurotic fibrosarcoma oncogene family, protein F (avian)
chr7_-_127308059 0.06 ENSMUST00000061468.9
B cell CLL/lymphoma 7C
chr8_+_26275314 0.06 ENSMUST00000038421.8
LSM1 homolog, mRNA degradation associated
chr16_+_80997580 0.06 ENSMUST00000037785.14
ENSMUST00000067602.5
neural cell adhesion molecule 2
chrX_-_160942713 0.06 ENSMUST00000087085.10
NHS actin remodeling regulator
chr9_+_109961048 0.06 ENSMUST00000088716.12
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1
chr18_+_42408418 0.06 ENSMUST00000091920.6
ENSMUST00000046972.14
ENSMUST00000236240.2
RNA binding motif protein 27
chr10_-_81186137 0.06 ENSMUST00000167481.8
high mobility group 20B
chr12_+_105302853 0.06 ENSMUST00000180458.9
Tcl1 upstream neural differentiation associated RNA
chr7_-_127307898 0.05 ENSMUST00000207019.2
B cell CLL/lymphoma 7C
chr13_-_12121831 0.05 ENSMUST00000021750.15
ENSMUST00000170156.3
ENSMUST00000220597.2
ryanodine receptor 2, cardiac
chr17_-_24388384 0.05 ENSMUST00000024932.12
ATPase, H+ transporting, lysosomal V0 subunit C
chr2_+_25070749 0.05 ENSMUST00000104999.4
Notch-regulated ankyrin repeat protein
chr8_-_25691380 0.05 ENSMUST00000084512.11
transforming, acidic coiled-coil containing protein 1
chr7_+_80643394 0.05 ENSMUST00000107353.3
zinc finger protein 592
chr7_-_44203319 0.05 ENSMUST00000208366.2
ENSMUST00000207737.2
ENSMUST00000107910.8
ENSMUST00000167197.8
ENSMUST00000128600.3
ENSMUST00000107911.8
ENSMUST00000073488.12
nuclear receptor subfamily 1, group H, member 2
chr2_-_181101158 0.05 ENSMUST00000155535.2
ENSMUST00000029106.13
ENSMUST00000087409.10
zinc finger and BTB domain containing 46
chr16_+_33504908 0.05 ENSMUST00000126532.2
heart development protein with EGF-like domains 1
chr9_+_109961079 0.05 ENSMUST00000197480.5
ENSMUST00000197984.5
ENSMUST00000199896.2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1
chr13_-_55661240 0.05 ENSMUST00000069929.13
ENSMUST00000069968.13
ENSMUST00000131306.8
ENSMUST00000046246.13
PDZ and LIM domain 7
chr11_+_60308077 0.05 ENSMUST00000070681.7
GID complex subunit 4, VID24 homolog
chrX_+_23559282 0.05 ENSMUST00000035766.13
ENSMUST00000101670.3
WD repeat domain 44
chr15_+_76131020 0.05 ENSMUST00000229380.2
glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)
chr7_-_127307791 0.05 ENSMUST00000205977.2
B cell CLL/lymphoma 7C
chr14_-_4808744 0.05 ENSMUST00000022303.17
ENSMUST00000091471.12
thyroid hormone receptor beta
chr17_+_56386628 0.05 ENSMUST00000226053.2
ENSMUST00000002911.10
HDGF like 2
chr9_-_118922534 0.05 ENSMUST00000010804.4
phospholipase C, delta 1
chr1_+_171330978 0.05 ENSMUST00000081527.2
Aly/REF export factor 2
chr14_-_100521888 0.05 ENSMUST00000226774.2
Kruppel-like factor 12

Network of associatons between targets according to the STRING database.

First level regulatory network of Egr1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0002581 negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002581) negative regulation of nitric oxide mediated signal transduction(GO:0010751) regulation of cGMP-mediated signaling(GO:0010752) negative regulation of endothelial cell chemotaxis(GO:2001027)
0.1 0.2 GO:1904766 negative regulation of macroautophagy by TORC1 signaling(GO:1904766)
0.1 0.2 GO:0060010 Sertoli cell fate commitment(GO:0060010)
0.1 0.3 GO:0070103 regulation of interleukin-6-mediated signaling pathway(GO:0070103)
0.1 0.2 GO:0098974 postsynaptic actin cytoskeleton organization(GO:0098974)
0.1 0.2 GO:2000384 regulation of ectoderm development(GO:2000383) negative regulation of ectoderm development(GO:2000384)
0.1 0.4 GO:0034616 response to laminar fluid shear stress(GO:0034616) cellular response to laminar fluid shear stress(GO:0071499)
0.1 0.3 GO:0045994 regulation of translational initiation by iron(GO:0006447) positive regulation of translational initiation by iron(GO:0045994)
0.0 0.2 GO:2000017 positive regulation of determination of dorsal identity(GO:2000017)
0.0 0.2 GO:0061017 primary lung bud formation(GO:0060431) hepatoblast differentiation(GO:0061017)
0.0 0.1 GO:0021682 nerve maturation(GO:0021682)
0.0 0.3 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.0 0.3 GO:0070317 negative regulation of G0 to G1 transition(GO:0070317)
0.0 0.1 GO:0071874 smooth endoplasmic reticulum calcium ion homeostasis(GO:0051563) cellular response to norepinephrine stimulus(GO:0071874)
0.0 0.1 GO:2000729 positive regulation of mesenchymal cell proliferation involved in ureter development(GO:2000729)
0.0 0.1 GO:0003017 lymph circulation(GO:0003017)
0.0 0.1 GO:0046604 positive regulation of mitotic centrosome separation(GO:0046604)
0.0 0.1 GO:1904828 regulation of hydrogen sulfide biosynthetic process(GO:1904826) positive regulation of hydrogen sulfide biosynthetic process(GO:1904828)
0.0 0.1 GO:1905077 negative regulation of interleukin-17 secretion(GO:1905077)
0.0 0.1 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.1 GO:0090345 nitrate catabolic process(GO:0043602) nitric oxide catabolic process(GO:0046210) cellular organohalogen metabolic process(GO:0090345) cellular organofluorine metabolic process(GO:0090346)
0.0 0.3 GO:0072513 positive regulation of secondary heart field cardioblast proliferation(GO:0072513)
0.0 0.2 GO:0071898 regulation of estrogen receptor binding(GO:0071898) negative regulation of estrogen receptor binding(GO:0071899)
0.0 0.1 GO:1900738 positive regulation of phospholipase C-activating G-protein coupled receptor signaling pathway(GO:1900738)
0.0 0.1 GO:0036015 response to interleukin-3(GO:0036015) cellular response to interleukin-3(GO:0036016)
0.0 0.2 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
0.0 0.1 GO:0032888 regulation of spindle elongation(GO:0032887) regulation of mitotic spindle elongation(GO:0032888) anastral spindle assembly(GO:0055048) protein localization to spindle pole body(GO:0071988) regulation of protein localization to spindle pole body(GO:1902363) positive regulation of protein localization to spindle pole body(GO:1902365) positive regulation of mitotic spindle elongation(GO:1902846)
0.0 0.2 GO:0032796 uropod organization(GO:0032796) early endosome to recycling endosome transport(GO:0061502)
0.0 0.6 GO:0097091 synaptic vesicle clustering(GO:0097091)
0.0 0.3 GO:0032927 positive regulation of activin receptor signaling pathway(GO:0032927)
0.0 0.2 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.0 0.1 GO:0086046 membrane depolarization during SA node cell action potential(GO:0086046)
0.0 0.1 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.0 0.1 GO:0070650 actin filament bundle distribution(GO:0070650)
0.0 0.1 GO:0010701 positive regulation of norepinephrine secretion(GO:0010701)
0.0 0.1 GO:0003220 left ventricular cardiac muscle tissue morphogenesis(GO:0003220)
0.0 0.1 GO:0060399 positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.0 0.2 GO:1901838 positive regulation of transcription of nuclear large rRNA transcript from RNA polymerase I promoter(GO:1901838) regulation of rRNA processing(GO:2000232)
0.0 0.1 GO:0007621 negative regulation of female receptivity(GO:0007621)
0.0 0.1 GO:2001200 positive regulation of dendritic cell differentiation(GO:2001200)
0.0 0.1 GO:0035938 estradiol secretion(GO:0035938) regulation of estradiol secretion(GO:2000864)
0.0 0.1 GO:0007199 G-protein coupled receptor signaling pathway coupled to cGMP nucleotide second messenger(GO:0007199)
0.0 0.2 GO:0021842 directional guidance of interneurons involved in migration from the subpallium to the cortex(GO:0021840) chemorepulsion involved in interneuron migration from the subpallium to the cortex(GO:0021842)
0.0 0.0 GO:0046881 positive regulation of follicle-stimulating hormone secretion(GO:0046881)
0.0 0.3 GO:0061179 negative regulation of insulin secretion involved in cellular response to glucose stimulus(GO:0061179)
0.0 0.0 GO:0072720 response to sorbitol(GO:0072708) response to dithiothreitol(GO:0072720)
0.0 0.2 GO:0021873 forebrain neuroblast division(GO:0021873)
0.0 0.1 GO:0032485 regulation of Ral protein signal transduction(GO:0032485)
0.0 0.1 GO:0090187 positive regulation of pancreatic juice secretion(GO:0090187)
0.0 0.5 GO:0000462 maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000462)
0.0 0.1 GO:2001015 negative regulation of skeletal muscle cell differentiation(GO:2001015)
0.0 0.2 GO:0030238 male sex determination(GO:0030238)
0.0 0.1 GO:0009405 pathogenesis(GO:0009405)
0.0 0.1 GO:0044791 modulation by host of viral release from host cell(GO:0044789) positive regulation by host of viral release from host cell(GO:0044791)
0.0 0.3 GO:0021516 dorsal spinal cord development(GO:0021516)
0.0 0.2 GO:0007042 lysosomal lumen acidification(GO:0007042)
0.0 0.0 GO:0060084 synaptic transmission involved in micturition(GO:0060084)
0.0 0.0 GO:0002270 plasmacytoid dendritic cell activation(GO:0002270)
0.0 0.0 GO:0019509 L-methionine biosynthetic process from methylthioadenosine(GO:0019509)
0.0 0.4 GO:0060065 uterus development(GO:0060065)
0.0 0.0 GO:2000049 positive regulation of cell-cell adhesion mediated by cadherin(GO:2000049)
0.0 0.1 GO:1903715 regulation of aerobic respiration(GO:1903715)
0.0 0.1 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.0 0.1 GO:0035372 protein localization to microtubule(GO:0035372)
0.0 0.0 GO:2000312 regulation of kainate selective glutamate receptor activity(GO:2000312)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0036020 endolysosome membrane(GO:0036020)
0.1 0.3 GO:0031680 G-protein beta/gamma-subunit complex(GO:0031680)
0.0 0.4 GO:0005577 fibrinogen complex(GO:0005577)
0.0 0.2 GO:0005956 protein kinase CK2 complex(GO:0005956)
0.0 0.1 GO:0002945 cyclin K-CDK12 complex(GO:0002944) cyclin K-CDK13 complex(GO:0002945)
0.0 0.4 GO:0000812 Swr1 complex(GO:0000812)
0.0 0.2 GO:0045261 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.0 0.2 GO:0045298 tubulin complex(GO:0045298)
0.0 0.1 GO:0031372 UBC13-MMS2 complex(GO:0031372)
0.0 0.2 GO:0001651 dense fibrillar component(GO:0001651)
0.0 0.1 GO:0032021 NELF complex(GO:0032021)
0.0 0.1 GO:0061673 mitotic spindle astral microtubule(GO:0061673)
0.0 0.1 GO:0034991 nuclear meiotic cohesin complex(GO:0034991)
0.0 0.1 GO:0070722 Tle3-Aes complex(GO:0070722)
0.0 0.0 GO:0032156 septin cytoskeleton(GO:0032156)
0.0 0.2 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.1 GO:0002111 BRCA2-BRAF35 complex(GO:0002111)
0.0 0.3 GO:0035102 PRC1 complex(GO:0035102)
0.0 0.1 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.0 0.1 GO:1990246 uniplex complex(GO:1990246)
0.0 0.1 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.1 GO:0097513 myosin II filament(GO:0097513)
0.0 0.2 GO:0035267 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 0.1 GO:0071141 SMAD protein complex(GO:0071141)
0.0 0.1 GO:0072487 MSL complex(GO:0072487)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0070052 collagen V binding(GO:0070052)
0.1 0.2 GO:0098973 structural constituent of synapse(GO:0098918) structural constituent of postsynaptic actin cytoskeleton(GO:0098973)
0.0 0.2 GO:0045131 pre-mRNA branch point binding(GO:0045131)
0.0 0.3 GO:0004111 creatine kinase activity(GO:0004111)
0.0 0.2 GO:0016909 JUN kinase activity(GO:0004705) SAP kinase activity(GO:0016909)
0.0 0.2 GO:0047493 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.0 0.1 GO:0035500 MH2 domain binding(GO:0035500)
0.0 0.2 GO:0044547 rRNA primary transcript binding(GO:0042134) DNA topoisomerase binding(GO:0044547)
0.0 0.1 GO:0034211 GTP-dependent protein kinase activity(GO:0034211)
0.0 0.1 GO:0047291 lactosylceramide alpha-2,3-sialyltransferase activity(GO:0047291)
0.0 0.1 GO:0008941 nitric oxide dioxygenase activity(GO:0008941) oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of two atoms of oxygen into one donor(GO:0016708) iron-cytochrome-c reductase activity(GO:0047726)
0.0 0.1 GO:0033149 FFAT motif binding(GO:0033149)
0.0 0.1 GO:0036033 mediator complex binding(GO:0036033)
0.0 0.4 GO:0044323 retinoic acid-responsive element binding(GO:0044323)
0.0 0.1 GO:0086059 voltage-gated calcium channel activity involved SA node cell action potential(GO:0086059)
0.0 0.1 GO:0055056 dehydroascorbic acid transporter activity(GO:0033300) D-glucose transmembrane transporter activity(GO:0055056)
0.0 0.2 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.0 0.1 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.0 0.1 GO:0005219 ryanodine-sensitive calcium-release channel activity(GO:0005219)
0.0 0.1 GO:0034191 apolipoprotein A-I receptor binding(GO:0034191)
0.0 0.1 GO:0034647 histone demethylase activity (H3-trimethyl-K4 specific)(GO:0034647)
0.0 0.3 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.0 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.0 0.1 GO:0043237 laminin-1 binding(GO:0043237)
0.0 0.1 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.0 0.2 GO:0005522 profilin binding(GO:0005522)
0.0 0.2 GO:0008190 eukaryotic initiation factor 4E binding(GO:0008190)
0.0 0.5 GO:0031369 translation initiation factor binding(GO:0031369)
0.0 0.2 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 0.1 GO:0051425 PTB domain binding(GO:0051425)
0.0 0.0 GO:2001069 glycogen binding(GO:2001069)
0.0 0.2 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.0 GO:0000401 open form four-way junction DNA binding(GO:0000401) crossed form four-way junction DNA binding(GO:0000402)
0.0 0.0 GO:0031752 D5 dopamine receptor binding(GO:0031752)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 PID TCR JNK PATHWAY JNK signaling in the CD4+ TCR pathway
0.0 0.1 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway
0.0 0.6 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.2 PID DNA PK PATHWAY DNA-PK pathway in nonhomologous end joining

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 REACTOME DOPAMINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Dopamine Neurotransmitter Release Cycle
0.0 0.3 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 0.0 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)
0.0 0.1 REACTOME IRAK1 RECRUITS IKK COMPLEX Genes involved in IRAK1 recruits IKK complex