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avrg: GFI1 WT vs 36n/n vs KD

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Results for En1

Z-value: 1.08

Motif logo

Transcription factors associated with En1

Gene Symbol Gene ID Gene Info
ENSMUSG00000058665.9 engrailed 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
En1mm39_v1_chr1_+_120530134_1205301470.424.8e-01Click!

Activity profile of En1 motif

Sorted Z-values of En1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr9_+_110867807 0.66 ENSMUST00000197575.2
lactotransferrin
chr1_+_40554513 0.62 ENSMUST00000027237.12
interleukin 18 receptor accessory protein
chr19_-_11618165 0.56 ENSMUST00000186023.7
membrane-spanning 4-domains, subfamily A, member 3
chr19_-_11618192 0.55 ENSMUST00000112984.4
membrane-spanning 4-domains, subfamily A, member 3
chr6_-_124410452 0.43 ENSMUST00000124998.2
ENSMUST00000238807.2
calsyntenin 3
chr17_+_34124078 0.40 ENSMUST00000172817.2
small integral membrane protein 40
chr9_+_121245036 0.38 ENSMUST00000211187.2
trafficking protein, kinesin binding 1
chr19_-_10079091 0.37 ENSMUST00000025567.9
fatty acid desaturase 2
chr2_-_71198091 0.35 ENSMUST00000151937.8
solute carrier family 25 (mitochondrial carrier, Aralar), member 12
chr2_+_72306503 0.34 ENSMUST00000102691.11
ENSMUST00000157019.2
cell division cycle associated 7
chr3_+_89970088 0.34 ENSMUST00000238911.2
ENSMUST00000029551.3
RIKEN cDNA 1700094D03 gene
chr19_-_32038838 0.32 ENSMUST00000096119.5
N-acylsphingosine amidohydrolase 2
chr19_-_40982576 0.31 ENSMUST00000117695.8
B cell linker
chr14_+_71011744 0.29 ENSMUST00000022698.8
docking protein 2
chr13_-_22190575 0.28 ENSMUST00000150547.3
protease, serine 16 (thymus)
chr1_-_105591362 0.28 ENSMUST00000187537.7
ENSMUST00000186485.7
ENSMUST00000190811.7
phosphatidylinositol glycan anchor biosynthesis, class N
chr5_-_121045568 0.28 ENSMUST00000080322.8
2'-5' oligoadenylate synthetase 1A
chr4_+_148125630 0.28 ENSMUST00000069604.15
methylenetetrahydrofolate reductase
chr17_+_18801989 0.26 ENSMUST00000165692.8
vomeronasal 2, receptor 96
chr3_+_96543143 0.25 ENSMUST00000165842.3
peroxisomal biogenesis factor 11 beta
chr1_+_177273226 0.25 ENSMUST00000077225.8
zinc finger and BTB domain containing 18
chr12_+_59060162 0.25 ENSMUST00000021379.8
gem nuclear organelle associated protein 2
chr6_+_70703409 0.25 ENSMUST00000103410.3
immunoglobulin kappa constant
chr17_+_36152559 0.24 ENSMUST00000174124.2
mediator of DNA damage checkpoint 1
chr17_-_44416619 0.24 ENSMUST00000143137.2
ectonucleotide pyrophosphatase/phosphodiesterase 4
chr6_-_69415741 0.24 ENSMUST00000103354.3
immunoglobulin kappa variable 4-59
chr12_-_36206750 0.24 ENSMUST00000221388.2
basic leucine zipper and W2 domains 2
chr11_+_87000032 0.22 ENSMUST00000020794.6
spindle and kinetochore associated complex subunit 2
chr2_+_14234198 0.22 ENSMUST00000028045.4
mannose receptor, C type 1
chr10_+_61010983 0.21 ENSMUST00000143207.8
ENSMUST00000148181.8
ENSMUST00000151886.8
thymus, brain and testes associated
chr4_-_115980813 0.21 ENSMUST00000102704.4
ENSMUST00000102705.10
RAD54 like (S. cerevisiae)
chr17_-_44416665 0.20 ENSMUST00000024757.14
ectonucleotide pyrophosphatase/phosphodiesterase 4
chr16_+_13721016 0.20 ENSMUST00000128757.8
Mpv17 transgene, kidney disease mutant-like
chr19_-_8691460 0.20 ENSMUST00000206560.2
ENSMUST00000205538.2
solute carrier family 3 (activators of dibasic and neutral amino acid transport), member 2
chr7_-_4448631 0.19 ENSMUST00000008579.14
retinol dehydrogenase 13 (all-trans and 9-cis)
chr1_-_88205233 0.19 ENSMUST00000065420.12
ENSMUST00000054674.15
Holliday junction recognition protein
chrX_+_134786600 0.18 ENSMUST00000180025.8
ENSMUST00000148374.8
ENSMUST00000068755.14
basic helix-loop-helix domain containing, class B9
chr5_+_137292865 0.18 ENSMUST00000052825.7
UFM1-specific peptidase 1
chr16_-_13720915 0.18 ENSMUST00000115803.9
pyridoxal-dependent decarboxylase domain containing 1
chr1_+_170472092 0.18 ENSMUST00000046792.9
olfactomedin-like 2B
chrX_-_100463810 0.18 ENSMUST00000118092.8
ENSMUST00000119699.8
zinc finger, MYM-type 3
chr8_+_89020845 0.17 ENSMUST00000098521.4
adenylate cyclase 7
chr9_+_113641615 0.17 ENSMUST00000111838.10
ENSMUST00000166734.10
ENSMUST00000214522.2
ENSMUST00000163895.3
CLIP associating protein 2
chr3_+_94600863 0.17 ENSMUST00000090848.10
ENSMUST00000173981.8
ENSMUST00000173849.8
ENSMUST00000174223.2
selenium binding protein 2
chr19_-_47003551 0.17 ENSMUST00000172239.3
5'-nucleotidase, cytosolic II
chr4_+_106924181 0.17 ENSMUST00000106758.8
ENSMUST00000145324.8
ENSMUST00000106760.8
cytochrome b5 reductase-like
chr9_+_107468146 0.17 ENSMUST00000195746.2
interferon-related developmental regulator 2
chr5_-_35886605 0.17 ENSMUST00000070203.14
SH3 domain and tetratricopeptide repeats 1
chr6_-_125213911 0.17 ENSMUST00000112282.3
ENSMUST00000112281.8
ENSMUST00000032486.13
CD27 antigen
chr14_-_70945434 0.16 ENSMUST00000228346.2
exportin 7
chr7_-_24997393 0.16 ENSMUST00000005583.12
platelet-activating factor acetylhydrolase, isoform 1b, subunit 3
chr7_+_46490899 0.16 ENSMUST00000147535.8
lactate dehydrogenase A
chr10_-_59838815 0.16 ENSMUST00000182116.8
anaphase promoting complex subunit 16
chr13_+_104315301 0.16 ENSMUST00000022225.12
ENSMUST00000069187.12
tripartite motif-containing 23
chr2_+_4022537 0.16 ENSMUST00000177457.8
FERM domain containing 4A
chr4_+_152123772 0.16 ENSMUST00000084116.13
ENSMUST00000103197.5
nucleolar protein 9
chr4_-_42665763 0.16 ENSMUST00000238770.2
interleukin 11 receptor, alpha chain 2
chr11_-_95733235 0.16 ENSMUST00000059026.10
ABI family member 3
chr2_+_25346841 0.16 ENSMUST00000114265.9
ENSMUST00000102918.3
chloride intracellular channel 3
chr7_-_24997291 0.15 ENSMUST00000148150.8
ENSMUST00000155118.2
platelet-activating factor acetylhydrolase, isoform 1b, subunit 3
chr4_-_56802266 0.15 ENSMUST00000030140.3
elongator complex protein 1
chr4_-_42168603 0.15 ENSMUST00000098121.4
predicted gene 13305
chr6_+_51447317 0.15 ENSMUST00000094623.10
chromobox 3
chr8_-_61436249 0.15 ENSMUST00000004430.14
ENSMUST00000110301.2
ENSMUST00000093490.9
chloride channel, voltage-sensitive 3
chr2_-_35351259 0.15 ENSMUST00000113001.9
ENSMUST00000113002.9
glycoprotein galactosyltransferase alpha 1, 3
chr2_-_89239943 0.15 ENSMUST00000217226.2
ENSMUST00000217237.2
olfactory receptor 1238
chr2_+_30156733 0.15 ENSMUST00000113645.8
ENSMUST00000133877.8
ENSMUST00000139719.8
ENSMUST00000113643.8
ENSMUST00000150695.8
phytanoyl-CoA dioxygenase domain containing 1
chr17_-_27816151 0.15 ENSMUST00000231742.2
nudix (nucleotide diphosphate linked moiety X)-type motif 3
chr3_-_86906591 0.14 ENSMUST00000063869.11
ENSMUST00000029717.4
CD1d1 antigen
chr6_+_57679455 0.14 ENSMUST00000072954.8
LanC (bacterial lantibiotic synthetase component C)-like 2
chr2_-_69542805 0.14 ENSMUST00000102706.4
ENSMUST00000073152.13
FAST kinase domains 1
chr16_-_30900181 0.14 ENSMUST00000055389.9
xyloside xylosyltransferase 1
chr9_+_8544143 0.14 ENSMUST00000050433.8
ENSMUST00000217462.2
transient receptor potential cation channel, subfamily C, member 6
chr5_+_90920294 0.14 ENSMUST00000031320.8
platelet factor 4
chr17_+_28945057 0.14 ENSMUST00000233003.2
predicted gene 4356
chr13_+_25127127 0.14 ENSMUST00000021773.13
glycosylphosphatidylinositol specific phospholipase D1
chr19_+_44994094 0.14 ENSMUST00000236685.2
twinkle mtDNA helicase
chr5_+_24791719 0.14 ENSMUST00000088295.9
ENSMUST00000121863.5
chondroitin polymerizing factor 2
chr4_+_118721846 0.14 ENSMUST00000106360.3
ENSMUST00000216589.2
olfactory receptor 1331
chr8_+_72022300 0.13 ENSMUST00000212111.2
solute carrier family 27 (fatty acid transporter), member 1
chr17_-_45883421 0.13 ENSMUST00000130406.2
heat shock protein 90 alpha (cytosolic), class B member 1
chr3_+_20011201 0.13 ENSMUST00000091309.12
ENSMUST00000108329.8
ENSMUST00000003714.13
ceruloplasmin
chr6_-_87798613 0.13 ENSMUST00000204169.2
predicted gene 45140
chr15_-_79658608 0.13 ENSMUST00000229644.2
ENSMUST00000023055.8
dynein, axonemal, light chain 4
chr16_+_35758836 0.13 ENSMUST00000114878.8
poly (ADP-ribose) polymerase family, member 9
chrX_-_135072979 0.13 ENSMUST00000163584.8
ENSMUST00000060101.10
transcription elongation factor A (SII)-like 8
chr10_-_127147609 0.13 ENSMUST00000037290.12
ENSMUST00000171564.8
methionine-tRNA synthetase 1
chr13_+_21295653 0.13 ENSMUST00000213326.2
ENSMUST00000215941.2
ENSMUST00000215207.2
ENSMUST00000213922.2
olfactory receptor 1369, pseudogene 1
chr1_-_134883645 0.12 ENSMUST00000045665.13
ENSMUST00000086444.6
ENSMUST00000112163.2
protein phosphatase 1, regulatory subunit 12B
chr19_-_46950355 0.12 ENSMUST00000236501.2
5'-nucleotidase, cytosolic II
chr11_+_49327451 0.12 ENSMUST00000215226.2
olfactory receptor 1388
chr10_+_128089965 0.12 ENSMUST00000060782.5
ENSMUST00000218722.2
apolipoprotein N
chr11_-_98915005 0.12 ENSMUST00000068031.8
topoisomerase (DNA) II alpha
chr16_-_26190578 0.12 ENSMUST00000023154.3
claudin 1
chr9_+_122717536 0.12 ENSMUST00000063980.8
zinc finger with KRAB and SCAN domains 7
chr1_-_133681419 0.12 ENSMUST00000125659.8
ENSMUST00000048953.14
ENSMUST00000165602.9
ATPase, Ca++ transporting, plasma membrane 4
chr1_-_63215812 0.12 ENSMUST00000185847.2
ENSMUST00000185732.7
ENSMUST00000188370.7
ENSMUST00000168099.9
NADH:ubiquinone oxidoreductase core subunit S1
chr17_+_26342474 0.12 ENSMUST00000025014.10
ENSMUST00000236166.2
ENSMUST00000127647.3
mitochondrial ribosomal protein L28
chrX_+_47235313 0.12 ENSMUST00000033427.7
SAM and SH3 domain containing 3
chr5_+_96989853 0.12 ENSMUST00000196126.2
annexin A3
chr12_-_108859123 0.12 ENSMUST00000161154.2
ENSMUST00000161410.8
tryptophanyl-tRNA synthetase
chr5_+_31652079 0.12 ENSMUST00000076949.13
ENSMUST00000202394.4
GPN-loop GTPase 1
chr9_+_92131797 0.12 ENSMUST00000093801.10
phospholipid scramblase 1
chr6_+_68247469 0.11 ENSMUST00000103321.3
immunoglobulin kappa variable 1-110
chr13_+_75987987 0.11 ENSMUST00000022082.8
ENSMUST00000223120.2
ENSMUST00000220523.2
glutaredoxin
chrX_+_138464065 0.11 ENSMUST00000113027.8
ring finger protein 128
chr18_-_39620115 0.11 ENSMUST00000097592.9
ENSMUST00000115571.8
nuclear receptor subfamily 3, group C, member 1
chr9_+_81745723 0.11 ENSMUST00000057067.10
ENSMUST00000189832.7
ENSMUST00000189391.2
meiotic double-stranded break formation protein 4
chr14_+_55120777 0.11 ENSMUST00000022806.10
BCL2-like 2
chr2_+_28417800 0.11 ENSMUST00000238699.2
ral guanine nucleotide dissociation stimulator
chr2_-_91274967 0.11 ENSMUST00000064652.14
ENSMUST00000102594.11
ENSMUST00000094835.9
RIKEN cDNA 1110051M20 gene
chr7_-_34755985 0.11 ENSMUST00000130491.3
CCAAT/enhancer binding protein (C/EBP), gamma
chr10_+_116013256 0.11 ENSMUST00000155606.8
ENSMUST00000128399.2
protein tyrosine phosphatase, receptor type, R
chr13_-_48746836 0.11 ENSMUST00000238995.2
protein tyrosine phosphatase domain containing 1
chrX_-_100463395 0.11 ENSMUST00000117901.8
ENSMUST00000120201.8
ENSMUST00000117637.8
ENSMUST00000134005.2
ENSMUST00000121520.8
zinc finger, MYM-type 3
chr4_-_106656976 0.11 ENSMUST00000145061.8
ENSMUST00000102762.10
acyl-CoA thioesterase 11
chr9_+_108820846 0.11 ENSMUST00000198140.5
ENSMUST00000051873.15
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4
chr7_-_80020830 0.10 ENSMUST00000205436.2
ENSMUST00000098346.5
mannosidase 2, alpha 2
chr6_-_56878854 0.10 ENSMUST00000101367.9
5'-nucleotidase, cytosolic III
chr1_+_88154727 0.10 ENSMUST00000061013.13
ENSMUST00000113130.8
maestro heat-like repeat family member 2A
chr17_+_34416689 0.10 ENSMUST00000173441.9
proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7)
chr9_+_64024429 0.10 ENSMUST00000034969.14
lactase-like
chr7_-_126399208 0.10 ENSMUST00000133514.8
ENSMUST00000151137.8
aldolase A, fructose-bisphosphate
chr10_-_8632519 0.10 ENSMUST00000212869.2
SAM and SH3 domain containing 1
chr1_-_191307648 0.10 ENSMUST00000027933.11
denticleless E3 ubiquitin protein ligase
chr6_+_92069376 0.10 ENSMUST00000113463.8
nuclear receptor subfamily 2, group C, member 2
chr3_+_152101080 0.10 ENSMUST00000106103.8
zinc finger, ZZ domain containing 3
chr11_+_75239259 0.10 ENSMUST00000044530.3
SET and MYND domain containing 4
chr8_-_27618643 0.10 ENSMUST00000033877.6
BRF2, RNA polymerase III transcription initiation factor 50kDa subunit
chr12_+_117480099 0.10 ENSMUST00000109691.4
Rap guanine nucleotide exchange factor (GEF) 5
chr2_-_35332101 0.10 ENSMUST00000131745.8
glycoprotein galactosyltransferase alpha 1, 3
chr5_+_137628377 0.10 ENSMUST00000175968.8
leucine-rich repeats and calponin homology (CH) domain containing 4
chr5_-_110927803 0.10 ENSMUST00000112426.8
pseudouridine synthase 1
chr6_-_87786736 0.10 ENSMUST00000032134.9
RAB43, member RAS oncogene family
chr10_-_56104732 0.09 ENSMUST00000099739.5
TBC1 domain family, member 32
chr2_-_11558703 0.09 ENSMUST00000192949.6
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
chr5_+_31079177 0.09 ENSMUST00000031053.15
ENSMUST00000202752.2
ketohexokinase
chr4_-_149760488 0.09 ENSMUST00000118704.8
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit delta
chr6_+_29859372 0.09 ENSMUST00000115238.10
S-adenosylhomocysteine hydrolase-like 2
chr16_+_38279289 0.09 ENSMUST00000099816.3
ENSMUST00000232409.2
CD80 antigen
chr14_-_33996185 0.09 ENSMUST00000227006.2
shieldin complex subunit 2
chr17_-_23990512 0.09 ENSMUST00000226460.2
FLYWCH-type zinc finger 1
chr15_-_79658584 0.09 ENSMUST00000069877.12
dynein, axonemal, light chain 4
chr12_-_36206626 0.09 ENSMUST00000220828.2
basic leucine zipper and W2 domains 2
chr17_-_31417834 0.09 ENSMUST00000236793.2
transmembrane protease, serine 3
chr14_-_70405288 0.09 ENSMUST00000129174.8
ENSMUST00000125300.3
PDZ and LIM domain 2
chr9_-_119813724 0.09 ENSMUST00000213936.2
cysteine-serine-rich nuclear protein 1
chr6_-_50374048 0.09 ENSMUST00000136926.3
oxysterol binding protein-like 3
chr7_+_30264835 0.09 ENSMUST00000043850.14
IGF-like family receptor 1
chrX_+_20570145 0.09 ENSMUST00000033383.3
ubiquitin specific peptidase 11
chr6_+_68402550 0.09 ENSMUST00000103323.3
immunoglobulin kappa variable 16-104
chr19_-_8775935 0.09 ENSMUST00000096261.5
polymerase (RNA) II (DNA directed) polypeptide G
chr12_+_76353835 0.09 ENSMUST00000220321.2
methylenetetrahydrofolate dehydrogenase (NADP+ dependent), methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthase
chr12_+_112940361 0.09 ENSMUST00000223368.2
ENSMUST00000223508.2
BTB (POZ) domain containing 6
chr7_-_121306476 0.09 ENSMUST00000046929.7
ubiquitin specific peptidase 31
chr7_-_126194097 0.09 ENSMUST00000058429.6
interleukin 27
chr14_-_62998561 0.09 ENSMUST00000053959.7
ENSMUST00000223585.2
integrator complex subunit 6
chr9_-_45847344 0.09 ENSMUST00000034590.4
transgelin
chr17_-_75858835 0.09 ENSMUST00000234785.2
ENSMUST00000112507.4
family with sequence similarity 98, member A
chr3_-_14843512 0.09 ENSMUST00000094365.11
carbonic anhydrase 1
chr4_+_115685257 0.09 ENSMUST00000030477.4
MOB kinase activator 3C
chr7_+_83281167 0.08 ENSMUST00000075418.15
StAR-related lipid transfer (START) domain containing 5
chr17_+_34416707 0.08 ENSMUST00000025196.9
proteasome (prosome, macropain) subunit, beta type 8 (large multifunctional peptidase 7)
chr4_-_123611974 0.08 ENSMUST00000137312.2
ENSMUST00000106206.8
NADH:ubiquinone oxidoreductase core subunit S5
chrX_-_56326951 0.08 ENSMUST00000114735.9
Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6
chr9_+_65494469 0.08 ENSMUST00000239405.2
ENSMUST00000047099.13
ENSMUST00000131483.3
ENSMUST00000141046.3
PIF1 5'-to-3' DNA helicase
chr6_+_86381201 0.08 ENSMUST00000095754.10
ENSMUST00000095753.9
cytotoxic granule-associated RNA binding protein 1
chrX_+_135950334 0.08 ENSMUST00000047852.8
family with sequence similarity 199, X-linked
chr10_-_25076008 0.08 ENSMUST00000100012.3
A kinase (PRKA) anchor protein 7
chr9_+_111011327 0.08 ENSMUST00000216430.2
leucine rich repeat (in FLII) interacting protein 2
chr9_+_111011388 0.08 ENSMUST00000217117.2
leucine rich repeat (in FLII) interacting protein 2
chrX_-_55643429 0.08 ENSMUST00000059899.3
membrane magnesium transporter 1
chr9_+_54858388 0.08 ENSMUST00000171900.2
proteasome subunit alpha 4
chr6_-_69204417 0.08 ENSMUST00000103346.3
immunoglobulin kappa chain variable 4-72
chr12_+_98234884 0.08 ENSMUST00000075072.6
G-protein coupled receptor 65
chr16_-_13720949 0.08 ENSMUST00000023361.12
ENSMUST00000115802.2
pyridoxal-dependent decarboxylase domain containing 1
chr14_+_55120875 0.08 ENSMUST00000134077.2
ENSMUST00000172844.8
ENSMUST00000133397.4
ENSMUST00000227108.2
predicted gene 20521
BCL2-like 2
chr7_+_51537645 0.08 ENSMUST00000208711.2
growth arrest specific 2
chr15_-_78056618 0.08 ENSMUST00000229476.2
intraflagellar transport 27
chr2_-_155199300 0.07 ENSMUST00000165234.2
ENSMUST00000077626.13
phosphatidylinositol glycan anchor biosynthesis, class U
chr8_+_124750133 0.07 ENSMUST00000034457.9
URB2 ribosome biogenesis 2 homolog (S. cerevisiae)
chr4_-_44066960 0.07 ENSMUST00000173234.8
ENSMUST00000173274.2
glucosamine (UDP-N-acetyl)-2-epimerase/N-acetylmannosamine kinase
chr7_+_125307060 0.07 ENSMUST00000124223.8
ENSMUST00000069660.13
katanin interacting protein
chr19_-_11243530 0.07 ENSMUST00000169159.3
membrane-spanning 4-domains, subfamily A, member 1
chr16_+_20367327 0.07 ENSMUST00000003319.6
ENSMUST00000232680.2
ENSMUST00000232490.2
ATP-binding cassette, sub-family F (GCN20), member 3
chr3_-_96812610 0.07 ENSMUST00000029738.14
G protein-coupled receptor 89
chr4_+_122910382 0.07 ENSMUST00000102649.4
tRNA isopentenyltransferase 1
chr11_+_72687080 0.07 ENSMUST00000207107.2
zinc finger, ZZ-type with EF hand domain 1
chr10_+_4382467 0.07 ENSMUST00000095893.11
ENSMUST00000118544.8
ENSMUST00000117489.8
acidic residue methyltransferase 1
chr1_+_163875783 0.07 ENSMUST00000027874.6
selectin, endothelial cell
chr12_+_102710008 0.07 ENSMUST00000057416.8
transmembrane protein 251
chr13_-_49473695 0.07 ENSMUST00000110086.2
FYVE, RhoGEF and PH domain containing 3
chr6_+_90179768 0.07 ENSMUST00000078371.6
vomeronasal 1 receptor, A8
chr10_-_18890281 0.07 ENSMUST00000146388.2
tumor necrosis factor, alpha-induced protein 3
chrX_+_139857640 0.07 ENSMUST00000112971.2
autophagy related 4A, cysteine peptidase
chr1_+_105591595 0.07 ENSMUST00000039173.13
ENSMUST00000086721.10
ENSMUST00000190501.7
RAB11 binding and LisH domain, coiled-coil and HEAT repeat containing
chr16_-_45830575 0.07 ENSMUST00000130481.2
phosphatidylinositol-specific phospholipase C, X domain containing 2
chr17_-_25105277 0.06 ENSMUST00000234583.2
ENSMUST00000234968.2
ENSMUST00000044252.7
nucleotide binding protein 2
chr9_-_44891626 0.06 ENSMUST00000002101.12
ENSMUST00000160886.2
CD3 antigen, gamma polypeptide
chr16_-_55755160 0.06 ENSMUST00000122280.8
ENSMUST00000121703.3
centrosomal protein 97

Network of associatons between targets according to the STRING database.

First level regulatory network of En1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:1900191 biofilm formation(GO:0042710) single-species biofilm formation(GO:0044010) single-species biofilm formation in or on host organism(GO:0044407) membrane disruption in other organism(GO:0051673) regulation of single-species biofilm formation(GO:1900190) negative regulation of single-species biofilm formation(GO:1900191) regulation of single-species biofilm formation in or on host organism(GO:1900228) negative regulation of single-species biofilm formation in or on host organism(GO:1900229)
0.1 0.4 GO:0098957 anterograde axonal transport of mitochondrion(GO:0098957)
0.1 0.3 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.1 0.2 GO:0033580 protein glycosylation at cell surface(GO:0033575) protein galactosylation at cell surface(GO:0033580) protein galactosylation(GO:0042125)
0.1 0.3 GO:0070829 heterochromatin maintenance(GO:0070829)
0.1 0.2 GO:0000448 cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000448)
0.1 0.3 GO:0044375 regulation of peroxisome size(GO:0044375)
0.0 0.1 GO:0097401 synaptic vesicle lumen acidification(GO:0097401)
0.0 0.1 GO:0048003 positive regulation of interleukin-4 biosynthetic process(GO:0045404) antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.0 0.1 GO:1903660 transforming growth factor beta activation(GO:0036363) regulation of complement-dependent cytotoxicity(GO:1903659) negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.0 0.1 GO:1903348 positive regulation of bicellular tight junction assembly(GO:1903348)
0.0 0.1 GO:0010751 negative regulation of nitric oxide mediated signal transduction(GO:0010751) negative regulation of cellular amino acid metabolic process(GO:0045763)
0.0 0.2 GO:0060356 leucine import(GO:0060356)
0.0 0.1 GO:0044376 RNA polymerase II complex import to nucleus(GO:0044376) RNA polymerase III complex localization to nucleus(GO:1990022)
0.0 0.1 GO:0071544 diphosphoinositol polyphosphate catabolic process(GO:0071544)
0.0 0.1 GO:1901421 positive regulation of response to alcohol(GO:1901421)
0.0 0.2 GO:0006659 phosphatidylserine biosynthetic process(GO:0006659)
0.0 0.1 GO:0006507 GPI anchor release(GO:0006507) regulation of high-density lipoprotein particle clearance(GO:0010982)
0.0 0.4 GO:1902474 positive regulation of protein localization to synapse(GO:1902474)
0.0 0.2 GO:0010730 negative regulation of hydrogen peroxide biosynthetic process(GO:0010730)
0.0 0.2 GO:0035660 MyD88-dependent toll-like receptor 4 signaling pathway(GO:0035660)
0.0 0.1 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.0 0.2 GO:0045347 negative regulation of MHC class II biosynthetic process(GO:0045347)
0.0 0.2 GO:0034080 CENP-A containing nucleosome assembly(GO:0034080) CENP-A containing chromatin organization(GO:0061641)
0.0 0.1 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.0 0.1 GO:0042138 meiotic DNA double-strand break formation(GO:0042138)
0.0 0.1 GO:0002358 B cell homeostatic proliferation(GO:0002358)
0.0 0.2 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.0 0.2 GO:0039692 single stranded viral RNA replication via double stranded DNA intermediate(GO:0039692)
0.0 0.4 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.1 GO:0034285 response to sucrose(GO:0009744) response to disaccharide(GO:0034285)
0.0 0.2 GO:0009644 response to high light intensity(GO:0009644)
0.0 0.1 GO:0034148 regulation of granuloma formation(GO:0002631) negative regulation of granuloma formation(GO:0002632) regulation of toll-like receptor 5 signaling pathway(GO:0034147) negative regulation of toll-like receptor 5 signaling pathway(GO:0034148) negative regulation of nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070429)
0.0 0.1 GO:0009257 histidine biosynthetic process(GO:0000105) 10-formyltetrahydrofolate biosynthetic process(GO:0009257)
0.0 0.4 GO:0045078 positive regulation of interferon-gamma biosynthetic process(GO:0045078)
0.0 0.1 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.0 0.2 GO:2000582 regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 0.1 GO:0016266 O-glycan processing(GO:0016266)
0.0 0.4 GO:0006152 purine nucleoside catabolic process(GO:0006152) purine ribonucleoside catabolic process(GO:0046130)
0.0 0.2 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.1 GO:0006553 lysine metabolic process(GO:0006553)
0.0 0.1 GO:2000587 negative regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000587)
0.0 0.2 GO:0060011 Sertoli cell proliferation(GO:0060011)
0.0 0.1 GO:1904826 regulation of hydrogen sulfide biosynthetic process(GO:1904826) positive regulation of hydrogen sulfide biosynthetic process(GO:1904828)
0.0 0.2 GO:0019660 glucose catabolic process to lactate(GO:0019659) glycolytic fermentation(GO:0019660) glucose catabolic process to lactate via pyruvate(GO:0019661)
0.0 0.1 GO:0072434 signal transduction involved in G2 DNA damage checkpoint(GO:0072425) signal transduction involved in mitotic G2 DNA damage checkpoint(GO:0072434)
0.0 0.1 GO:0051697 protein delipidation(GO:0051697)
0.0 0.1 GO:1900170 negative regulation of glucocorticoid mediated signaling pathway(GO:1900170)
0.0 0.1 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.0 0.1 GO:0034214 protein hexamerization(GO:0034214)
0.0 0.0 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.0 0.2 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0 0.1 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.0 0.0 GO:0071500 cellular response to nitrosative stress(GO:0071500)
0.0 0.2 GO:0071361 cellular response to ethanol(GO:0071361)
0.0 0.0 GO:0061739 protein lipidation involved in autophagosome assembly(GO:0061739)
0.0 0.1 GO:0044806 G-quadruplex DNA unwinding(GO:0044806)
0.0 0.0 GO:0009609 response to symbiont(GO:0009608) response to symbiotic bacterium(GO:0009609)
0.0 0.0 GO:0030845 regulation of inositol-polyphosphate 5-phosphatase activity(GO:0010924) positive regulation of inositol-polyphosphate 5-phosphatase activity(GO:0010925) phospholipase C-inhibiting G-protein coupled receptor signaling pathway(GO:0030845) regulation of cell diameter(GO:0060305)
0.0 0.1 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 0.0 GO:2000156 regulation of retrograde vesicle-mediated transport, Golgi to ER(GO:2000156)
0.0 0.1 GO:0090034 regulation of chaperone-mediated protein complex assembly(GO:0090034) positive regulation of chaperone-mediated protein complex assembly(GO:0090035)
0.0 0.1 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.0 0.1 GO:0033031 positive regulation of neutrophil apoptotic process(GO:0033031)
0.0 0.1 GO:0010636 positive regulation of mitochondrial fusion(GO:0010636)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.6 GO:0044218 other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
0.1 0.2 GO:1904511 cortical microtubule plus-end(GO:1903754) cytoplasmic microtubule plus-end(GO:1904511)
0.0 0.3 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.0 0.2 GO:1990111 spermatoproteasome complex(GO:1990111)
0.0 0.1 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.0 0.1 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.0 0.4 GO:1904115 axon cytoplasm(GO:1904115)
0.0 0.1 GO:0070939 Dsl1p complex(GO:0070939)
0.0 0.2 GO:0000940 condensed chromosome outer kinetochore(GO:0000940)
0.0 0.2 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.1 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 0.0 GO:1990622 CHOP-C/EBP complex(GO:0036488) CHOP-ATF3 complex(GO:1990622)
0.0 0.2 GO:0020005 symbiont-containing vacuole membrane(GO:0020005)
0.0 0.1 GO:0042765 GPI-anchor transamidase complex(GO:0042765)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0047710 bis(5'-adenosyl)-triphosphatase activity(GO:0047710)
0.1 0.3 GO:0004489 methylenetetrahydrofolate reductase (NAD(P)H) activity(GO:0004489)
0.1 0.3 GO:0051377 mannose-ethanolamine phosphotransferase activity(GO:0051377)
0.1 0.3 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.0 0.6 GO:0004908 interleukin-1 receptor activity(GO:0004908)
0.0 0.3 GO:0047179 platelet-activating factor acetyltransferase activity(GO:0047179)
0.0 0.4 GO:0004768 stearoyl-CoA 9-desaturase activity(GO:0004768)
0.0 0.1 GO:0033680 ATP-dependent DNA/RNA helicase activity(GO:0033680)
0.0 0.6 GO:0005068 transmembrane receptor protein tyrosine kinase adaptor activity(GO:0005068)
0.0 0.3 GO:0017040 ceramidase activity(GO:0017040)
0.0 0.1 GO:0019153 protein-disulfide reductase (glutathione) activity(GO:0019153)
0.0 0.1 GO:0072320 volume-sensitive chloride channel activity(GO:0072320)
0.0 0.2 GO:0047276 N-acetyllactosaminide 3-alpha-galactosyltransferase activity(GO:0047276)
0.0 0.1 GO:0004572 mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase activity(GO:0004572)
0.0 0.2 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.0 0.1 GO:0004454 ketohexokinase activity(GO:0004454)
0.0 0.1 GO:0003918 DNA topoisomerase type II (ATP-hydrolyzing) activity(GO:0003918) DNA topoisomerase II activity(GO:0061505)
0.0 0.1 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.0 0.3 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.0 0.1 GO:0035252 UDP-xylosyltransferase activity(GO:0035252)
0.0 0.7 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 0.2 GO:0051731 polynucleotide 5'-hydroxyl-kinase activity(GO:0051731)
0.0 0.2 GO:0003873 6-phosphofructo-2-kinase activity(GO:0003873)
0.0 0.1 GO:0004329 formate-tetrahydrofolate ligase activity(GO:0004329)
0.0 0.1 GO:0034432 endopolyphosphatase activity(GO:0000298) diphosphoinositol-polyphosphate diphosphatase activity(GO:0008486) bis(5'-adenosyl)-hexaphosphatase activity(GO:0034431) bis(5'-adenosyl)-pentaphosphatase activity(GO:0034432)
0.0 0.1 GO:0071723 lipopeptide binding(GO:0071723)
0.0 0.1 GO:0001032 RNA polymerase III type 3 promoter DNA binding(GO:0001032)
0.0 0.1 GO:0002135 CTP binding(GO:0002135)
0.0 0.2 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0 0.2 GO:0036310 annealing helicase activity(GO:0036310)
0.0 0.1 GO:0038049 glucocorticoid receptor activity(GO:0004883) transcription factor activity, ligand-activated RNA polymerase II transcription factor binding(GO:0038049) glucocorticoid-activated RNA polymerase II transcription factor binding transcription factor activity(GO:0038051)
0.0 0.1 GO:0008422 beta-glucosidase activity(GO:0008422)
0.0 0.4 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.4 GO:0050811 GABA receptor binding(GO:0050811)
0.0 0.1 GO:0004630 phospholipase D activity(GO:0004630)
0.0 0.1 GO:0008761 UDP-N-acetylglucosamine 2-epimerase activity(GO:0008761)
0.0 0.1 GO:0019834 phospholipase A2 inhibitor activity(GO:0019834)
0.0 0.2 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 0.0 GO:0033829 O-fucosylpeptide 3-beta-N-acetylglucosaminyltransferase activity(GO:0033829)
0.0 0.2 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.0 GO:0004342 glucosamine-6-phosphate deaminase activity(GO:0004342)
0.0 0.2 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.1 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.2 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.1 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
0.0 0.1 GO:0004322 ferroxidase activity(GO:0004322) oxidoreductase activity, oxidizing metal ions, oxygen as acceptor(GO:0016724)
0.0 0.1 GO:0004315 3-oxoacyl-[acyl-carrier-protein] synthase activity(GO:0004315)
0.0 0.1 GO:0004064 arylesterase activity(GO:0004064)
0.0 0.1 GO:0030911 TPR domain binding(GO:0030911)
0.0 0.1 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.0 0.1 GO:0004332 fructose-bisphosphate aldolase activity(GO:0004332)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.8 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 REACTOME AMYLOIDS Genes involved in Amyloids
0.0 0.3 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.3 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.1 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.0 0.2 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.2 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.4 REACTOME REGULATION OF SIGNALING BY CBL Genes involved in Regulation of signaling by CBL
0.0 0.2 REACTOME ADENYLATE CYCLASE ACTIVATING PATHWAY Genes involved in Adenylate cyclase activating pathway