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avrg: GFI1 WT vs 36n/n vs KD

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Results for Epas1_Bcl3

Z-value: 4.14

Motif logo

Transcription factors associated with Epas1_Bcl3

Gene Symbol Gene ID Gene Info
ENSMUSG00000024140.11 endothelial PAS domain protein 1
ENSMUSG00000053175.18 B cell leukemia/lymphoma 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Epas1mm39_v1_chr17_+_87061117_870611370.991.1e-03Click!
Bcl3mm39_v1_chr7_-_19556612_195567120.983.8e-03Click!

Activity profile of Epas1_Bcl3 motif

Sorted Z-values of Epas1_Bcl3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr11_+_34264757 8.40 ENSMUST00000165963.9
ENSMUST00000093192.4
inhibitory synaptic factor family member 2B
chr5_-_129030367 4.21 ENSMUST00000111346.6
ENSMUST00000200470.5
RIMS binding protein 2
chr6_+_136931519 3.67 ENSMUST00000137768.2
phosphodiesterase 6H, cGMP-specific, cone, gamma
chrX_+_55777139 3.27 ENSMUST00000023854.10
ENSMUST00000114769.9
four and a half LIM domains 1
chr10_-_10958031 3.18 ENSMUST00000105561.9
ENSMUST00000044306.13
glutamate receptor, metabotropic 1
chr16_-_23339548 3.12 ENSMUST00000089883.7
mannan-binding lectin serine peptidase 1
chr8_-_3744167 2.98 ENSMUST00000005678.6
Fc receptor, IgE, low affinity II, alpha polypeptide
chr2_-_69416365 2.70 ENSMUST00000100051.9
ENSMUST00000092551.5
ENSMUST00000080953.12
low density lipoprotein receptor-related protein 2
chr19_+_23736205 2.47 ENSMUST00000025830.9
amyloid beta (A4) precursor protein binding, family A, member 1
chr7_+_131568167 2.45 ENSMUST00000045840.5
G protein-coupled receptor 26
chr11_+_112673041 2.34 ENSMUST00000000579.3
SRY (sex determining region Y)-box 9
chr17_+_78815493 2.30 ENSMUST00000024880.11
ENSMUST00000232859.2
vitrin
chr18_-_25887173 2.24 ENSMUST00000225477.2
CUGBP, Elav-like family member 4
chr9_-_29874401 2.18 ENSMUST00000075069.11
neurotrimin
chr1_+_173501215 2.14 ENSMUST00000085876.12
interferon activated gene 208
chr6_+_15185202 2.14 ENSMUST00000154448.2
forkhead box P2
chr4_+_124774692 2.14 ENSMUST00000059343.7
Eph receptor A10
chr5_-_121147593 1.89 ENSMUST00000079204.9
rabphilin 3A
chr17_-_81977590 1.88 ENSMUST00000234923.2
solute carrier family 8 (sodium/calcium exchanger), member 1
chr6_+_91661074 1.83 ENSMUST00000205480.2
ENSMUST00000206545.2
solute carrier family 6 (neurotransmitter transporter, taurine), member 6
chr7_+_43959637 1.82 ENSMUST00000107938.8
SH3 and multiple ankyrin repeat domains 1
chr6_+_65648574 1.81 ENSMUST00000054351.6
neuron-derived neurotrophic factor
chr15_+_82159398 1.73 ENSMUST00000023095.14
ENSMUST00000230365.2
septin 3
chr9_-_50639230 1.70 ENSMUST00000118707.2
ENSMUST00000034566.15
DIX domain containing 1
chr3_-_102111892 1.68 ENSMUST00000029453.13
VANGL planar cell polarity 1
chr18_-_25886908 1.64 ENSMUST00000115816.3
ENSMUST00000223704.2
CUGBP, Elav-like family member 4
chr4_-_131871797 1.63 ENSMUST00000056336.2
opioid receptor, delta 1
chr1_+_40505136 1.59 ENSMUST00000087983.8
ENSMUST00000195684.6
ENSMUST00000108044.4
interleukin 18 receptor 1
chr6_+_91661034 1.52 ENSMUST00000032185.9
solute carrier family 6 (neurotransmitter transporter, taurine), member 6
chr2_+_68691902 1.44 ENSMUST00000176018.2
ceramide synthase 6
chr1_-_36978602 1.43 ENSMUST00000027290.12
transmembrane protein 131
chr7_+_110367375 1.42 ENSMUST00000170374.8
adenosine monophosphate deaminase 3
chr2_-_104324035 1.39 ENSMUST00000111124.8
homeodomain interacting protein kinase 3
chr5_-_30619246 1.34 ENSMUST00000114747.9
ENSMUST00000074171.10
otoferlin
chr12_-_103979900 1.34 ENSMUST00000058464.5
serine (or cysteine) peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 9
chr17_-_33440626 1.32 ENSMUST00000213751.2
ENSMUST00000213642.2
ENSMUST00000215450.2
ENSMUST00000208645.3
olfactory receptor 1564
chr8_+_109429732 1.29 ENSMUST00000188994.2
zinc finger homeobox 3
chr8_-_112356957 1.28 ENSMUST00000070004.4
lactate dehydrogenase D
chr13_-_96269076 1.27 ENSMUST00000161263.8
synaptic vesicle glycoprotein 2c
chr1_+_42734051 1.25 ENSMUST00000239323.2
ENSMUST00000199521.5
ENSMUST00000176807.3
POU domain, class 3, transcription factor 3
predicted gene 20646
chr1_-_171480441 1.25 ENSMUST00000192195.6
SLAM family member 7
chr7_+_19699291 1.22 ENSMUST00000094753.6
carcinoembryonic antigen-related cell adhesion molecule 20
chr2_+_4305273 1.20 ENSMUST00000175669.8
FERM domain containing 4A
chr5_-_135518098 1.18 ENSMUST00000201998.2
huntingtin interacting protein 1
chr6_-_142910094 1.18 ENSMUST00000032421.4
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
chr17_-_32503107 1.17 ENSMUST00000237692.2
bromodomain containing 4
chr16_-_38533597 1.15 ENSMUST00000023487.5
Rho GTPase activating protein 31
chr8_+_79754980 1.09 ENSMUST00000087927.11
ENSMUST00000098614.9
zinc finger protein 827
chr16_+_57173456 1.08 ENSMUST00000159816.8
filamin A interacting protein 1-like
chr11_-_102255999 1.06 ENSMUST00000006749.10
solute carrier family 4 (anion exchanger), member 1
chr5_+_99002293 1.05 ENSMUST00000031278.6
ENSMUST00000200388.2
bone morphogenetic protein 3
chr17_-_32503060 1.05 ENSMUST00000003726.16
ENSMUST00000121285.8
ENSMUST00000120276.9
bromodomain containing 4
chr4_-_20778847 1.04 ENSMUST00000102998.4
Na+/K+ transporting ATPase interacting 3
chr18_+_61058684 1.03 ENSMUST00000102888.10
ENSMUST00000025519.11
calcium/calmodulin-dependent protein kinase II alpha
chr5_+_135197228 1.02 ENSMUST00000111187.10
ENSMUST00000111188.5
ENSMUST00000202606.3
B cell CLL/lymphoma 7B
chr15_+_64689543 1.01 ENSMUST00000180105.2
predicted gene, 21798
chr7_+_3352019 1.01 ENSMUST00000100301.11
protein kinase C, gamma
chr7_-_140535899 0.99 ENSMUST00000081649.10
interferon induced transmembrane protein 2
chr8_-_85526972 0.96 ENSMUST00000099070.10
nuclear factor I/X
chr8_-_85526653 0.95 ENSMUST00000126806.2
ENSMUST00000076715.13
nuclear factor I/X
chrX_+_7708295 0.93 ENSMUST00000115667.10
ENSMUST00000115668.10
ENSMUST00000115665.2
OTU domain containing 5
chr3_+_105811712 0.92 ENSMUST00000000574.3
adenosine A3 receptor
chr9_-_102231884 0.92 ENSMUST00000035129.14
ENSMUST00000085169.12
ENSMUST00000149800.3
Eph receptor B1
chr9_+_89791943 0.89 ENSMUST00000189545.2
ENSMUST00000034909.11
ENSMUST00000034912.6
RAS protein-specific guanine nucleotide-releasing factor 1
chr10_-_5500636 0.85 ENSMUST00000215295.2
ENSMUST00000041639.7
spectrin repeat containing, nuclear envelope 1
chr6_-_112924205 0.83 ENSMUST00000088373.11
SLIT-ROBO Rho GTPase activating protein 3
chrX_-_63320543 0.82 ENSMUST00000114679.2
ENSMUST00000069926.14
SLIT and NTRK-like family, member 4
chr15_-_5137975 0.80 ENSMUST00000118365.3
caspase recruitment domain family, member 6
chr6_+_119152210 0.79 ENSMUST00000112777.9
ENSMUST00000073909.6
decapping mRNA 1B
chr6_+_128376729 0.78 ENSMUST00000001561.12
nuclear receptor interacting protein 2
chr7_+_110371811 0.78 ENSMUST00000005829.13
adenosine monophosphate deaminase 3
chr10_-_127587576 0.77 ENSMUST00000079692.6
G protein-coupled receptor 182
chr15_+_84565174 0.77 ENSMUST00000065499.5
proline rich 5 (renal)
chr17_+_75772475 0.77 ENSMUST00000095204.6
RAS, guanyl releasing protein 3
chr2_-_165996716 0.76 ENSMUST00000139266.2
sulfatase 2
chr7_-_48531344 0.76 ENSMUST00000119223.2
E2F transcription factor 8
chr9_-_50650663 0.74 ENSMUST00000117093.2
ENSMUST00000121634.8
DIX domain containing 1
chr2_+_68691778 0.73 ENSMUST00000028426.9
ceramide synthase 6
chr3_-_52012462 0.73 ENSMUST00000121440.4
mastermind like transcriptional coactivator 3
chr17_-_57385490 0.73 ENSMUST00000011623.9
DENN/MADD domain containing 1C
chr17_-_38370970 0.71 ENSMUST00000216476.2
olfactory receptor 129
chr7_-_140590605 0.71 ENSMUST00000026565.7
interferon induced transmembrane protein 3
chr18_+_82928782 0.71 ENSMUST00000235793.2
zinc finger protein 516
chr5_-_91550853 0.70 ENSMUST00000121044.6
betacellulin, epidermal growth factor family member
chr1_-_158785937 0.70 ENSMUST00000159861.9
pappalysin 2
chr11_-_97040858 0.69 ENSMUST00000118375.8
TBK1 binding protein 1
chr1_-_74002156 0.69 ENSMUST00000191367.2
tensin 1
chr15_+_81820954 0.69 ENSMUST00000038757.8
ENSMUST00000230633.2
cold shock domain containing C2, RNA binding
chr4_+_32983417 0.68 ENSMUST00000084747.6
Ras-related GTP binding D
chr11_-_72302520 0.68 ENSMUST00000108500.8
ENSMUST00000050226.7
smoothelin-like 2
chr12_+_4284009 0.67 ENSMUST00000179139.3
peptidyl-tRNA hydrolase domain containing 1
chr13_+_94495457 0.67 ENSMUST00000022196.5
adaptor-related protein complex 3, beta 1 subunit
chr10_-_120312374 0.67 ENSMUST00000072777.14
ENSMUST00000159699.2
high mobility group AT-hook 2
chr11_+_94900677 0.67 ENSMUST00000055947.10
sterile alpha motif domain containing 14
chr6_+_128376844 0.66 ENSMUST00000120405.4
nuclear receptor interacting protein 2
chr1_-_74544946 0.65 ENSMUST00000044260.11
ENSMUST00000186282.7
ubiquitin specific peptidase 37
chr13_+_42205790 0.65 ENSMUST00000220525.2
human immunodeficiency virus type I enhancer binding protein 1
chr5_+_135197137 0.65 ENSMUST00000031692.12
B cell CLL/lymphoma 7B
chr9_+_44394080 0.64 ENSMUST00000220303.2
B cell CLL/lymphoma 9-like
chr13_-_92268156 0.61 ENSMUST00000151408.9
ENSMUST00000216219.2
RAS protein-specific guanine nucleotide-releasing factor 2
chr19_+_10366450 0.61 ENSMUST00000073899.6
synaptotagmin VII
chr2_-_165997179 0.61 ENSMUST00000088086.4
sulfatase 2
chr5_+_130477642 0.61 ENSMUST00000111288.4
calneuron 1
chr19_+_45036220 0.61 ENSMUST00000084493.8
sideroflexin 3
chr5_+_109567554 0.60 ENSMUST00000232833.2
ENSMUST00000232722.2
ENSMUST00000233536.2
ENSMUST00000171841.3
ENSMUST00000233038.2
ENSMUST00000233724.2
vomeronasal 2, receptor 17
chr17_-_56019571 0.59 ENSMUST00000086876.7
ENSMUST00000233557.2
ENSMUST00000233972.2
protection of telomeres 1B
chr3_-_131196213 0.59 ENSMUST00000197057.2
sphingomyelin synthase 2
chr13_+_42205491 0.58 ENSMUST00000060148.6
human immunodeficiency virus type I enhancer binding protein 1
chr2_+_169474916 0.58 ENSMUST00000109159.3
teashirt zinc finger family member 2
chr12_-_14202041 0.58 ENSMUST00000020926.8
LRAT domain containing 1
chr9_+_108174052 0.56 ENSMUST00000035230.7
aminomethyltransferase
chr14_-_100521888 0.55 ENSMUST00000226774.2
Kruppel-like factor 12
chr12_+_17740831 0.54 ENSMUST00000071858.5
hippocalcin-like 1
chr10_+_80330669 0.54 ENSMUST00000051773.9
one cut domain, family member 3
chr17_+_57412325 0.54 ENSMUST00000039490.9
tumor necrosis factor (ligand) superfamily, member 9
chr3_-_96501443 0.53 ENSMUST00000145001.2
ENSMUST00000091924.10
polymerase (RNA) III (DNA directed) polypeptide G like
chr8_-_123980908 0.53 ENSMUST00000122363.8
VPS9 domain containing 1
chr11_-_72098239 0.52 ENSMUST00000238653.2
ENSMUST00000108505.2
RIKEN cDNA 4933427D14 gene
chr2_+_174485327 0.52 ENSMUST00000059452.6
zinc finger protein 831
chr12_-_77008799 0.51 ENSMUST00000218640.2
Max protein
chr7_-_140676623 0.50 ENSMUST00000209352.2
single immunoglobulin and toll-interleukin 1 receptor (TIR) domain
chr14_+_33645539 0.49 ENSMUST00000168727.3
growth differentiation factor 10
chr3_-_105839980 0.49 ENSMUST00000098758.5
RIKEN cDNA I830077J02 gene
chrX_+_7630182 0.49 ENSMUST00000144900.2
ENSMUST00000115677.8
ENSMUST00000101695.9
ENSMUST00000115678.3
transcription factor E3
chr3_+_130904000 0.49 ENSMUST00000029611.14
ENSMUST00000106341.9
ENSMUST00000066849.13
lymphoid enhancer binding factor 1
chr14_+_84680993 0.48 ENSMUST00000071370.7
protocadherin 17
chr6_+_124986224 0.48 ENSMUST00000112427.8
zinc finger protein 384
chr8_-_41087793 0.48 ENSMUST00000173957.2
ENSMUST00000048898.17
ENSMUST00000174205.8
myotubularin related protein 7
chr16_-_89940652 0.47 ENSMUST00000114124.9
T cell lymphoma invasion and metastasis 1
chr18_+_53596570 0.47 ENSMUST00000236096.2
PR domain containing 6
chr6_+_129022843 0.46 ENSMUST00000032257.10
ENSMUST00000204320.2
killer cell lectin-like receptor subfamily B member 1F
chrX_+_158197568 0.46 ENSMUST00000112471.9
MAP7 domain containing 2
chr17_-_74766131 0.45 ENSMUST00000052124.9
NLR family, CARD domain containing 4
chr13_+_89687915 0.45 ENSMUST00000022108.9
hyaluronan and proteoglycan link protein 1
chr11_-_28534260 0.45 ENSMUST00000093253.10
ENSMUST00000109502.9
ENSMUST00000042534.15
coiled-coil domain containing 85A
chr7_-_24937276 0.44 ENSMUST00000071739.12
ENSMUST00000108411.2
glycogen synthase kinase 3 alpha
chr18_+_82928959 0.44 ENSMUST00000171238.8
zinc finger protein 516
chr15_+_44059531 0.44 ENSMUST00000038856.14
ENSMUST00000110289.4
thyrotropin releasing hormone receptor
chr3_-_127019496 0.43 ENSMUST00000182064.9
ENSMUST00000182452.8
ankyrin 2, brain
chrX_-_161612373 0.43 ENSMUST00000041370.11
ENSMUST00000112316.9
ENSMUST00000112315.2
taxilin gamma
chr15_-_83054369 0.43 ENSMUST00000162834.3
cytochrome b5 reductase 3
chr7_-_100512579 0.42 ENSMUST00000142885.2
ENSMUST00000008462.11
RELT tumor necrosis factor receptor
chr2_-_113588983 0.42 ENSMUST00000099575.4
gremlin 1, DAN family BMP antagonist
chr16_-_31133622 0.41 ENSMUST00000115230.2
ENSMUST00000130560.8
apolipoprotein D
chr5_-_68004743 0.40 ENSMUST00000072971.13
ENSMUST00000113652.8
ENSMUST00000113651.8
ENSMUST00000037380.15
ATPase, aminophospholipid transporter (APLT), class I, type 8A, member 1
chr13_-_110417421 0.40 ENSMUST00000223922.2
RAB3C, member RAS oncogene family
chr4_+_97665992 0.40 ENSMUST00000107062.9
ENSMUST00000052018.12
ENSMUST00000107057.8
nuclear factor I/A
chr7_+_79309938 0.39 ENSMUST00000035977.9
TOPBP1-interacting checkpoint and replication regulator
chrX_+_100342749 0.39 ENSMUST00000118111.8
ENSMUST00000130555.8
ENSMUST00000151528.8
neuroligin 3
chr17_+_34362281 0.39 ENSMUST00000236519.2
histocompatibility 2, class II, locus Mb2
chr6_-_122587005 0.38 ENSMUST00000032211.5
growth differentiation factor 3
chr19_+_8641369 0.38 ENSMUST00000035444.10
ENSMUST00000163785.2
cholinergic receptor, muscarinic 1, CNS
chr11_-_97466035 0.38 ENSMUST00000107596.9
ENSMUST00000238314.2
ENSMUST00000238597.2
ENSMUST00000238342.2
SRC kinase signaling inhibitor 1
chr7_+_43284131 0.37 ENSMUST00000032663.10
carcinoembryonic antigen-related cell adhesion molecule 18
chr11_+_66802807 0.37 ENSMUST00000123434.3
phosphoinositide-interacting regulator of transient receptor potential channels
chr10_+_25317309 0.37 ENSMUST00000217929.2
ENSMUST00000220121.2
erythrocyte membrane protein band 4.1 like 2
chr2_-_91014163 0.36 ENSMUST00000077941.13
ENSMUST00000111381.9
ENSMUST00000111372.8
ENSMUST00000111371.8
ENSMUST00000075269.10
ENSMUST00000066473.12
MAP-kinase activating death domain
chr17_+_38032699 0.36 ENSMUST00000207771.3
olfactory receptor 120
chr3_-_146388165 0.36 ENSMUST00000124931.8
ENSMUST00000147113.2
sterile alpha motif domain containing 13
chr17_+_35354430 0.35 ENSMUST00000173535.8
ENSMUST00000173952.8
BCL2-associated athanogene 6
chr12_-_77008952 0.35 ENSMUST00000110395.11
ENSMUST00000082136.7
Max protein
chr5_-_134776101 0.34 ENSMUST00000015138.13
elastin
chr9_-_89620461 0.33 ENSMUST00000060700.4
ENSMUST00000185470.3
ankyrin repeat domain 34C
chr3_+_89072096 0.32 ENSMUST00000121212.9
ENSMUST00000152205.5
ENSMUST00000090927.12
ENSMUST00000148265.8
ENSMUST00000121931.8
CDC-like kinase 2
chr4_-_141325517 0.32 ENSMUST00000131317.8
ENSMUST00000006381.11
ENSMUST00000129602.8
filamin binding LIM protein 1
chr19_+_34585322 0.32 ENSMUST00000076249.6
interferon-induced protein with tetratricopeptide repeats 3B
chr10_-_128481833 0.32 ENSMUST00000133342.10
IKAROS family zinc finger 4
chr6_-_136150076 0.32 ENSMUST00000053880.13
glutamate receptor, ionotropic, NMDA2B (epsilon 2)
chr9_+_121471782 0.31 ENSMUST00000035115.5
vasoactive intestinal peptide receptor 1
chr18_+_65022035 0.31 ENSMUST00000224385.3
ENSMUST00000163516.9
neural precursor cell expressed, developmentally down-regulated gene 4-like
chr5_-_136594286 0.31 ENSMUST00000176172.8
cut-like homeobox 1
chr5_+_43672856 0.31 ENSMUST00000076939.10
C1q and tumor necrosis factor related protein 7
chr11_-_116545071 0.31 ENSMUST00000021166.6
cytoglobin
chr6_+_124986193 0.31 ENSMUST00000112428.8
zinc finger protein 384
chr16_+_91184661 0.30 ENSMUST00000139503.2
interferon (alpha and beta) receptor 2
chr12_+_37930169 0.30 ENSMUST00000221176.2
diacylglycerol kinase, beta
chr6_-_88852017 0.30 ENSMUST00000145944.3
podocalyxin-like 2
chr2_+_147206910 0.30 ENSMUST00000109968.3
paired box 1
chr7_+_4693603 0.30 ENSMUST00000120836.8
BR serine/threonine kinase 1
chr17_+_37180437 0.30 ENSMUST00000060524.11
tripartite motif-containing 10
chr1_+_183766572 0.30 ENSMUST00000048655.8
dual specificity phosphatase 10
chr13_+_31990604 0.30 ENSMUST00000062292.5
forkhead box C1
chr8_+_12981662 0.30 ENSMUST00000238472.2
mcf.2 transforming sequence-like
chr5_+_143636977 0.29 ENSMUST00000110727.2
cytohesin 3
chr11_+_95603494 0.29 ENSMUST00000107717.8
zinc finger protein 652
chr18_-_43571345 0.29 ENSMUST00000121805.9
dihydropyrimidinase-like 3
chr11_-_72097821 0.29 ENSMUST00000204457.3
predicted gene, 43951
chr7_-_105218472 0.28 ENSMUST00000187683.7
ENSMUST00000210079.2
ENSMUST00000187051.7
ENSMUST00000189265.7
ENSMUST00000190369.7
amyloid beta (A4) precursor protein-binding, family B, member 1
chrX_-_36167148 0.28 ENSMUST00000239259.2
NF-kappaB repressing factor
chr5_+_138019523 0.28 ENSMUST00000171498.3
ENSMUST00000085886.3
sperm motility kinase 3A
chr10_-_42152684 0.28 ENSMUST00000175881.8
ENSMUST00000056974.4
ENSMUST00000105502.8
ENSMUST00000105501.2
forkhead box O3
chrX_+_7708034 0.28 ENSMUST00000033494.16
ENSMUST00000115666.8
OTU domain containing 5
chr11_-_97886997 0.28 ENSMUST00000042971.16
ADP-ribosylation factor-like 5C
chr7_-_30755007 0.28 ENSMUST00000206474.2
ENSMUST00000205807.2
ENSMUST00000039909.13
ENSMUST00000206305.2
ENSMUST00000205439.2
FXYD domain-containing ion transport regulator 1
chr4_+_137589548 0.28 ENSMUST00000102518.10
endothelin converting enzyme 1
chr6_-_85351588 0.27 ENSMUST00000204087.2
RAB11 family interacting protein 5 (class I)
chr19_+_26725589 0.27 ENSMUST00000207812.2
ENSMUST00000175791.9
ENSMUST00000207118.2
ENSMUST00000209085.2
ENSMUST00000112637.10
ENSMUST00000207054.2
ENSMUST00000208589.2
ENSMUST00000176475.9
ENSMUST00000176698.9
ENSMUST00000207832.2
ENSMUST00000177252.9
ENSMUST00000208712.2
ENSMUST00000208186.2
ENSMUST00000208806.2
ENSMUST00000208027.2
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr4_+_130640436 0.27 ENSMUST00000151698.8
lysosomal-associated protein transmembrane 5
chr3_-_9069745 0.27 ENSMUST00000120143.8
tumor protein D52
chr19_-_41732104 0.27 ENSMUST00000025993.10
slit guidance ligand 1

Network of associatons between targets according to the STRING database.

First level regulatory network of Epas1_Bcl3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.3 GO:0015734 beta-alanine transport(GO:0001762) taurine transport(GO:0015734)
0.8 2.3 GO:0035622 intrahepatic bile duct development(GO:0035622) renal vesicle induction(GO:0072034)
0.7 3.5 GO:0099566 regulation of postsynaptic cytosolic calcium ion concentration(GO:0099566)
0.4 3.0 GO:0002925 positive regulation of humoral immune response mediated by circulating immunoglobulin(GO:0002925)
0.4 1.3 GO:0072233 ascending thin limb development(GO:0072021) thick ascending limb development(GO:0072023) metanephric ascending thin limb development(GO:0072218) metanephric thick ascending limb development(GO:0072233)
0.3 1.2 GO:1905077 negative regulation of interleukin-17 secretion(GO:1905077)
0.3 1.2 GO:2000588 positive regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000588)
0.3 1.3 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.3 0.8 GO:0032877 positive regulation of DNA endoreduplication(GO:0032877)
0.2 3.0 GO:0001867 complement activation, lectin pathway(GO:0001867)
0.2 1.6 GO:0038003 opioid receptor signaling pathway(GO:0038003)
0.2 1.4 GO:0014846 esophagus smooth muscle contraction(GO:0014846)
0.2 0.7 GO:0048003 antigen processing and presentation of lipid antigen via MHC class Ib(GO:0048003) antigen processing and presentation, exogenous lipid antigen via MHC class Ib(GO:0048007)
0.2 2.6 GO:0060501 positive regulation of epithelial cell proliferation involved in lung morphogenesis(GO:0060501)
0.2 1.5 GO:0098989 NMDA selective glutamate receptor signaling pathway(GO:0098989)
0.2 1.9 GO:0098735 positive regulation of the force of heart contraction(GO:0098735)
0.2 0.6 GO:2000331 regulation of terminal button organization(GO:2000331)
0.2 2.6 GO:1902866 regulation of retina development in camera-type eye(GO:1902866)
0.2 0.6 GO:0072695 negative regulation of DNA recombination at telomere(GO:0048239) regulation of DNA recombination at telomere(GO:0072695)
0.2 0.6 GO:1990926 short-term synaptic potentiation(GO:1990926)
0.2 0.6 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.2 0.6 GO:0006546 glycine catabolic process(GO:0006546) glycine decarboxylation via glycine cleavage system(GO:0019464)
0.2 1.8 GO:0046959 habituation(GO:0046959)
0.2 1.8 GO:0061042 vascular wound healing(GO:0061042)
0.2 2.1 GO:0021869 forebrain ventricular zone progenitor cell division(GO:0021869)
0.2 0.5 GO:1904092 regulation of autophagic cell death(GO:1904092) negative regulation of autophagic cell death(GO:1904093)
0.2 1.5 GO:0032264 IMP salvage(GO:0032264)
0.1 0.4 GO:0071879 positive regulation of adrenergic receptor signaling pathway(GO:0071879)
0.1 2.2 GO:0044154 histone H3-K14 acetylation(GO:0044154)
0.1 0.4 GO:1900158 negative regulation of bone mineralization involved in bone maturation(GO:1900158)
0.1 1.6 GO:0035655 interleukin-18-mediated signaling pathway(GO:0035655)
0.1 0.5 GO:0032696 negative regulation of interleukin-13 production(GO:0032696) trachea submucosa development(GO:0061152) trachea gland development(GO:0061153)
0.1 0.8 GO:0043578 nuclear matrix organization(GO:0043578) nuclear matrix anchoring at nuclear membrane(GO:0090292)
0.1 0.4 GO:1902277 negative regulation of pancreatic amylase secretion(GO:1902277)
0.1 3.9 GO:0045745 positive regulation of G-protein coupled receptor protein signaling pathway(GO:0045745)
0.1 0.9 GO:2001015 negative regulation of skeletal muscle cell differentiation(GO:2001015)
0.1 0.3 GO:1902256 apoptotic process involved in outflow tract morphogenesis(GO:0003275) regulation of apoptotic process involved in outflow tract morphogenesis(GO:1902256)
0.1 0.3 GO:0002661 B cell tolerance induction(GO:0002514) regulation of tolerance induction to self antigen(GO:0002649) regulation of B cell tolerance induction(GO:0002661) positive regulation of B cell tolerance induction(GO:0002663) endocardial cushion fusion(GO:0003274)
0.1 0.9 GO:0002441 histamine production involved in inflammatory response(GO:0002349) histamine secretion involved in inflammatory response(GO:0002441) histamine secretion by mast cell(GO:0002553)
0.1 1.9 GO:0021707 cerebellar granular layer formation(GO:0021684) cerebellar granule cell differentiation(GO:0021707)
0.1 1.7 GO:0043508 negative regulation of JUN kinase activity(GO:0043508)
0.1 0.8 GO:0031087 deadenylation-independent decapping of nuclear-transcribed mRNA(GO:0031087)
0.1 0.8 GO:0038203 TORC2 signaling(GO:0038203)
0.1 1.9 GO:0046597 negative regulation of viral entry into host cell(GO:0046597)
0.1 0.3 GO:0007197 adenylate cyclase-inhibiting G-protein coupled acetylcholine receptor signaling pathway(GO:0007197) phospholipase C-activating G-protein coupled acetylcholine receptor signaling pathway(GO:0007207)
0.1 2.2 GO:0014051 gamma-aminobutyric acid secretion(GO:0014051)
0.1 0.5 GO:0032423 regulation of mismatch repair(GO:0032423)
0.1 3.7 GO:0010972 negative regulation of G2/M transition of mitotic cell cycle(GO:0010972)
0.1 0.5 GO:0045585 regulation of cytotoxic T cell differentiation(GO:0045583) positive regulation of cytotoxic T cell differentiation(GO:0045585)
0.1 0.7 GO:0071233 response to leucine(GO:0043201) cellular response to leucine(GO:0071233)
0.1 0.3 GO:0061056 sclerotome development(GO:0061056)
0.1 2.7 GO:0010165 response to X-ray(GO:0010165)
0.1 0.4 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.1 0.5 GO:0061092 regulation of phospholipid translocation(GO:0061091) positive regulation of phospholipid translocation(GO:0061092)
0.1 0.6 GO:0006686 sphingomyelin biosynthetic process(GO:0006686)
0.1 1.3 GO:0016082 synaptic vesicle priming(GO:0016082)
0.1 0.2 GO:0035771 interleukin-4-mediated signaling pathway(GO:0035771) positive regulation of isotype switching to IgE isotypes(GO:0048295)
0.1 0.7 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.1 0.2 GO:0035521 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.1 0.4 GO:0036371 protein localization to M-band(GO:0036309) protein localization to T-tubule(GO:0036371) regulation of SA node cell action potential(GO:0098907)
0.0 1.8 GO:0048791 calcium ion-regulated exocytosis of neurotransmitter(GO:0048791)
0.0 0.4 GO:0048859 formation of anatomical boundary(GO:0048859)
0.0 0.3 GO:0050757 thymidylate synthase biosynthetic process(GO:0050757) regulation of thymidylate synthase biosynthetic process(GO:0050758) negative regulation of thymidylate synthase biosynthetic process(GO:0050760)
0.0 0.7 GO:0035871 protein K11-linked deubiquitination(GO:0035871)
0.0 0.4 GO:1903797 positive regulation of inorganic anion transmembrane transport(GO:1903797)
0.0 0.2 GO:0010980 regulation of vitamin D 24-hydroxylase activity(GO:0010979) positive regulation of vitamin D 24-hydroxylase activity(GO:0010980)
0.0 0.3 GO:0035585 calcium-mediated signaling using extracellular calcium source(GO:0035585)
0.0 0.4 GO:0036506 maintenance of unfolded protein(GO:0036506) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.0 0.3 GO:0015671 oxygen transport(GO:0015671)
0.0 0.1 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.0 0.7 GO:0035810 positive regulation of urine volume(GO:0035810)
0.0 0.3 GO:1901300 positive regulation of hydrogen peroxide-mediated programmed cell death(GO:1901300)
0.0 1.0 GO:0015701 bicarbonate transport(GO:0015701)
0.0 1.5 GO:2000310 regulation of N-methyl-D-aspartate selective glutamate receptor activity(GO:2000310)
0.0 0.5 GO:2000807 regulation of synaptic vesicle clustering(GO:2000807)
0.0 0.1 GO:0070649 formin-nucleated actin cable assembly(GO:0070649)
0.0 0.2 GO:0033563 dorsal/ventral axon guidance(GO:0033563)
0.0 0.5 GO:0051151 negative regulation of smooth muscle cell differentiation(GO:0051151)
0.0 4.1 GO:0010923 negative regulation of phosphatase activity(GO:0010923)
0.0 0.3 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.0 0.4 GO:0090073 positive regulation of protein homodimerization activity(GO:0090073)
0.0 2.5 GO:0007189 adenylate cyclase-activating G-protein coupled receptor signaling pathway(GO:0007189)
0.0 0.5 GO:0070269 pyroptosis(GO:0070269)
0.0 0.2 GO:1903758 regulation of postsynaptic density protein 95 clustering(GO:1902897) regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.0 1.8 GO:0046513 ceramide biosynthetic process(GO:0046513)
0.0 1.4 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.2 GO:0009992 cellular water homeostasis(GO:0009992)
0.0 0.1 GO:0010958 regulation of amino acid import(GO:0010958)
0.0 0.4 GO:0072540 T-helper cell lineage commitment(GO:0002295) T-helper 17 cell lineage commitment(GO:0072540)
0.0 0.4 GO:2001288 positive regulation of caveolin-mediated endocytosis(GO:2001288)
0.0 0.1 GO:0061073 ciliary body morphogenesis(GO:0061073)
0.0 0.1 GO:0045743 positive regulation of fibroblast growth factor receptor signaling pathway(GO:0045743)
0.0 0.2 GO:0035696 monocyte extravasation(GO:0035696) positive regulation of epithelial cell proliferation involved in wound healing(GO:0060054)
0.0 0.5 GO:0046838 phosphorylated carbohydrate dephosphorylation(GO:0046838) inositol phosphate dephosphorylation(GO:0046855)
0.0 0.2 GO:0060017 parathyroid gland development(GO:0060017)
0.0 1.4 GO:0010862 positive regulation of pathway-restricted SMAD protein phosphorylation(GO:0010862)
0.0 0.0 GO:0060849 regulation of transcription involved in lymphatic endothelial cell fate commitment(GO:0060849)
0.0 0.4 GO:1904776 regulation of protein localization to cell cortex(GO:1904776) positive regulation of protein localization to cell cortex(GO:1904778)
0.0 1.2 GO:0009409 response to cold(GO:0009409)
0.0 0.2 GO:0045085 negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.0 0.3 GO:0033623 regulation of integrin activation(GO:0033623)
0.0 0.1 GO:0007060 male meiosis chromosome segregation(GO:0007060)
0.0 0.3 GO:0045721 negative regulation of gluconeogenesis(GO:0045721)
0.0 0.1 GO:1900127 positive regulation of hyaluronan biosynthetic process(GO:1900127)
0.0 0.1 GO:0035735 intraciliary transport involved in cilium morphogenesis(GO:0035735)
0.0 0.4 GO:0019886 antigen processing and presentation of exogenous peptide antigen via MHC class II(GO:0019886)
0.0 1.3 GO:0006754 ATP biosynthetic process(GO:0006754)
0.0 1.0 GO:0032814 regulation of natural killer cell activation(GO:0032814)
0.0 0.8 GO:0010718 positive regulation of epithelial to mesenchymal transition(GO:0010718)
0.0 0.2 GO:0031914 negative regulation of synaptic plasticity(GO:0031914)
0.0 0.3 GO:0035455 response to interferon-alpha(GO:0035455)
0.0 0.2 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.0 0.1 GO:0003025 regulation of systemic arterial blood pressure by baroreceptor feedback(GO:0003025) vagus nerve development(GO:0021564)
0.0 1.2 GO:0034605 cellular response to heat(GO:0034605)
0.0 0.4 GO:0048266 behavioral response to pain(GO:0048266)
0.0 0.2 GO:1901249 regulation of lung goblet cell differentiation(GO:1901249) negative regulation of lung goblet cell differentiation(GO:1901250)
0.0 0.5 GO:0071539 protein localization to centrosome(GO:0071539)
0.0 0.3 GO:0050901 leukocyte tethering or rolling(GO:0050901)
0.0 0.3 GO:0035404 histone-serine phosphorylation(GO:0035404)
0.0 0.0 GO:0060912 cardiac cell fate specification(GO:0060912)
0.0 2.2 GO:0010811 positive regulation of cell-substrate adhesion(GO:0010811)
0.0 0.2 GO:0035235 ionotropic glutamate receptor signaling pathway(GO:0035235)
0.0 0.1 GO:0043320 natural killer cell degranulation(GO:0043320)
0.0 0.0 GO:0033577 protein glycosylation in endoplasmic reticulum(GO:0033577)
0.0 0.4 GO:0007212 dopamine receptor signaling pathway(GO:0007212)
0.0 0.2 GO:0007614 short-term memory(GO:0007614)
0.0 0.6 GO:0010761 fibroblast migration(GO:0010761)
0.0 0.1 GO:0099540 synaptic signaling via neuropeptide(GO:0099538) trans-synaptic signaling by neuropeptide(GO:0099540) trans-synaptic signaling by neuropeptide, modulating synaptic transmission(GO:0099551)
0.0 0.2 GO:0042118 endothelial cell activation(GO:0042118)
0.0 2.1 GO:0010977 negative regulation of neuron projection development(GO:0010977)
0.0 0.0 GO:1904252 negative regulation of bile acid biosynthetic process(GO:0070858) negative regulation of bile acid metabolic process(GO:1904252)
0.0 0.0 GO:0045079 negative regulation of chemokine biosynthetic process(GO:0045079)
0.0 0.4 GO:0061001 regulation of dendritic spine morphogenesis(GO:0061001)
0.0 0.1 GO:0060313 negative regulation of cellular extravasation(GO:0002692) negative regulation of neutrophil degranulation(GO:0043314) negative regulation of blood vessel remodeling(GO:0060313)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0099573 glutamatergic postsynaptic density(GO:0099573)
0.2 3.2 GO:0038037 G-protein coupled receptor dimeric complex(GO:0038037) G-protein coupled receptor complex(GO:0097648)
0.2 1.2 GO:0098890 extrinsic component of postsynaptic membrane(GO:0098890)
0.2 2.2 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.1 0.7 GO:1990131 Gtr1-Gtr2 GTPase complex(GO:1990131)
0.1 1.3 GO:0048787 presynaptic active zone membrane(GO:0048787)
0.1 2.3 GO:0005614 interstitial matrix(GO:0005614)
0.1 2.1 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.1 0.8 GO:0034992 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.1 0.5 GO:0072557 IPAF inflammasome complex(GO:0072557)
0.1 0.6 GO:1990907 beta-catenin-TCF complex(GO:1990907)
0.0 0.8 GO:0031932 TORC2 complex(GO:0031932)
0.0 0.7 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.0 0.6 GO:0032009 early phagosome(GO:0032009)
0.0 0.6 GO:0000783 telomere cap complex(GO:0000782) nuclear telomere cap complex(GO:0000783)
0.0 0.9 GO:0032433 filopodium tip(GO:0032433)
0.0 0.4 GO:0071818 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)
0.0 0.3 GO:0031095 platelet dense tubular network membrane(GO:0031095)
0.0 0.2 GO:0044316 cone cell pedicle(GO:0044316)
0.0 0.6 GO:0032279 asymmetric synapse(GO:0032279)
0.0 0.3 GO:1990812 growth cone filopodium(GO:1990812)
0.0 0.5 GO:0060091 kinocilium(GO:0060091)
0.0 0.4 GO:0042613 MHC class II protein complex(GO:0042613)
0.0 1.6 GO:0032590 dendrite membrane(GO:0032590)
0.0 0.3 GO:0033093 Weibel-Palade body(GO:0033093)
0.0 0.9 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.5 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 7.0 GO:0008021 synaptic vesicle(GO:0008021)
0.0 0.2 GO:0042583 chromaffin granule(GO:0042583)
0.0 3.0 GO:0014704 intercalated disc(GO:0014704)
0.0 1.6 GO:0016328 lateral plasma membrane(GO:0016328)
0.0 0.5 GO:0005666 DNA-directed RNA polymerase III complex(GO:0005666)
0.0 2.1 GO:0005905 clathrin-coated pit(GO:0005905)
0.0 0.9 GO:0071339 MLL1/2 complex(GO:0044665) MLL1 complex(GO:0071339)
0.0 0.5 GO:0031528 microvillus membrane(GO:0031528)
0.0 0.7 GO:0034451 centriolar satellite(GO:0034451)
0.0 0.6 GO:0032588 trans-Golgi network membrane(GO:0032588)
0.0 0.6 GO:0060077 inhibitory synapse(GO:0060077)
0.0 0.9 GO:0030173 integral component of Golgi membrane(GO:0030173)
0.0 0.2 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 2.1 GO:0043679 axon terminus(GO:0043679)
0.0 0.2 GO:0070382 exocytic vesicle(GO:0070382)
0.0 0.1 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.3 GO:0071564 npBAF complex(GO:0071564)
0.0 1.4 GO:0016605 PML body(GO:0016605)
0.0 0.1 GO:0005915 zonula adherens(GO:0005915)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
1.1 3.3 GO:0005368 beta-alanine transmembrane transporter activity(GO:0001761) taurine transmembrane transporter activity(GO:0005368) taurine:sodium symporter activity(GO:0005369)
1.1 3.2 GO:0099530 PLC activating G-protein coupled glutamate receptor activity(GO:0001639) G-protein coupled receptor activity involved in regulation of postsynaptic membrane potential(GO:0099530)
0.9 2.7 GO:0042954 lipoprotein transporter activity(GO:0042954)
0.6 1.9 GO:0099580 ion antiporter activity involved in regulation of postsynaptic membrane potential(GO:0099580)
0.4 2.2 GO:0034211 GTP-dependent protein kinase activity(GO:0034211)
0.4 3.1 GO:0005005 transmembrane-ephrin receptor activity(GO:0005005)
0.4 1.3 GO:0016898 D-lactate dehydrogenase (cytochrome) activity(GO:0004458) oxidoreductase activity, acting on the CH-OH group of donors, cytochrome as acceptor(GO:0016898)
0.4 1.6 GO:0042008 interleukin-18 receptor activity(GO:0042008)
0.4 3.0 GO:0019863 IgE binding(GO:0019863)
0.3 1.0 GO:0004698 calcium-dependent protein kinase C activity(GO:0004698)
0.3 1.6 GO:0004985 opioid receptor activity(GO:0004985)
0.3 1.8 GO:0030160 GKAP/Homer scaffold activity(GO:0030160) ankyrin repeat binding(GO:0071532)
0.2 2.2 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.2 1.2 GO:0003828 alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity(GO:0003828)
0.2 1.4 GO:0008449 N-acetylglucosamine-6-sulfatase activity(GO:0008449)
0.2 2.3 GO:0097157 pre-mRNA intronic binding(GO:0097157)
0.2 1.2 GO:0061578 Lys63-specific deubiquitinase activity(GO:0061578)
0.2 1.5 GO:0003876 AMP deaminase activity(GO:0003876) adenosine-phosphate deaminase activity(GO:0047623)
0.1 0.7 GO:0004045 aminoacyl-tRNA hydrolase activity(GO:0004045)
0.1 3.6 GO:0030553 cGMP binding(GO:0030553)
0.1 1.9 GO:0042301 phosphate ion binding(GO:0042301)
0.1 2.5 GO:0035612 AP-2 adaptor complex binding(GO:0035612)
0.1 1.7 GO:0001206 transcriptional repressor activity, RNA polymerase II distal enhancer sequence-specific binding(GO:0001206)
0.1 0.3 GO:0004999 vasoactive intestinal polypeptide receptor activity(GO:0004999)
0.1 0.4 GO:0030297 transmembrane receptor protein tyrosine kinase activator activity(GO:0030297)
0.1 0.6 GO:0033188 sphingomyelin synthase activity(GO:0033188) ceramide cholinephosphotransferase activity(GO:0047493)
0.1 0.3 GO:0005026 transforming growth factor beta receptor activity, type II(GO:0005026)
0.1 1.2 GO:0070700 BMP receptor binding(GO:0070700)
0.1 0.8 GO:0097642 calcitonin family receptor activity(GO:0097642)
0.1 0.3 GO:0016907 G-protein coupled acetylcholine receptor activity(GO:0016907)
0.1 1.0 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.1 0.3 GO:0004096 catalase activity(GO:0004096)
0.1 0.9 GO:0001609 G-protein coupled adenosine receptor activity(GO:0001609)
0.1 0.6 GO:0010521 telomerase inhibitor activity(GO:0010521)
0.1 0.5 GO:0030284 estrogen receptor activity(GO:0030284)
0.1 0.3 GO:0099583 neurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration(GO:0099583)
0.1 0.3 GO:0004904 interferon receptor activity(GO:0004904) type I interferon receptor activity(GO:0004905) type I interferon binding(GO:0019962)
0.1 0.2 GO:0005105 type 1 fibroblast growth factor receptor binding(GO:0005105)
0.1 0.5 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312)
0.1 3.1 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 2.6 GO:0036002 pre-mRNA binding(GO:0036002)
0.0 0.2 GO:0005222 intracellular cAMP activated cation channel activity(GO:0005222)
0.0 0.3 GO:0048495 Roundabout binding(GO:0048495)
0.0 1.4 GO:0004190 aspartic-type endopeptidase activity(GO:0004190)
0.0 3.0 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.9 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.2 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.0 0.8 GO:0005521 lamin binding(GO:0005521)
0.0 1.3 GO:0004993 G-protein coupled serotonin receptor activity(GO:0004993)
0.0 0.4 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0 0.7 GO:0003906 DNA-(apurinic or apyrimidinic site) lyase activity(GO:0003906)
0.0 0.2 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.9 GO:0000983 transcription factor activity, RNA polymerase II core promoter sequence-specific(GO:0000983)
0.0 0.3 GO:0035374 chondroitin sulfate binding(GO:0035374)
0.0 0.4 GO:0042731 PH domain binding(GO:0042731)
0.0 0.6 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 1.1 GO:0030742 GTP-dependent protein binding(GO:0030742)
0.0 0.4 GO:0050321 tau-protein kinase activity(GO:0050321)
0.0 1.3 GO:0071837 HMG box domain binding(GO:0071837)
0.0 0.2 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 0.2 GO:0005332 gamma-aminobutyric acid:sodium symporter activity(GO:0005332)
0.0 0.3 GO:0008301 DNA binding, bending(GO:0008301)
0.0 2.4 GO:0048306 calcium-dependent protein binding(GO:0048306)
0.0 0.3 GO:0048273 mitogen-activated protein kinase p38 binding(GO:0048273)
0.0 1.1 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 4.9 GO:0001078 transcriptional repressor activity, RNA polymerase II core promoter proximal region sequence-specific binding(GO:0001078)
0.0 0.3 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.4 GO:0015643 toxic substance binding(GO:0015643)
0.0 4.4 GO:0005539 glycosaminoglycan binding(GO:0005539)
0.0 0.1 GO:0004111 creatine kinase activity(GO:0004111)
0.0 1.4 GO:0048365 Rac GTPase binding(GO:0048365)
0.0 0.4 GO:0023026 MHC class II protein complex binding(GO:0023026)
0.0 3.7 GO:0044325 ion channel binding(GO:0044325)
0.0 0.5 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 0.1 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.3 GO:0035174 histone serine kinase activity(GO:0035174)
0.0 0.3 GO:0031005 filamin binding(GO:0031005)
0.0 0.2 GO:0001011 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.4 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.6 GO:0005160 transforming growth factor beta receptor binding(GO:0005160)
0.0 0.5 GO:0003899 DNA-directed RNA polymerase activity(GO:0003899)
0.0 0.1 GO:0051011 microtubule minus-end binding(GO:0051011)
0.0 0.0 GO:0008900 hydrogen:potassium-exchanging ATPase activity(GO:0008900)
0.0 2.1 GO:0005088 Ras guanyl-nucleotide exchange factor activity(GO:0005088)
0.0 0.1 GO:0060175 brain-derived neurotrophic factor-activated receptor activity(GO:0060175)
0.0 0.3 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.5 GO:0005544 calcium-dependent phospholipid binding(GO:0005544)
0.0 0.5 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.2 GO:0042975 peroxisome proliferator activated receptor binding(GO:0042975)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 4.6 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.1 2.1 PID HEDGEHOG 2PATHWAY Signaling events mediated by the Hedgehog family
0.0 1.6 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 1.4 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.6 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 2.7 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 0.9 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 0.9 PID MYC PATHWAY C-MYC pathway
0.0 0.7 PID ERBB NETWORK PATHWAY ErbB receptor signaling network
0.0 0.2 SIG IL4RECEPTOR IN B LYPHOCYTES Genes related to IL4 rceptor signaling in B lymphocytes
0.0 5.2 NABA ECM REGULATORS Genes encoding enzymes and their regulators involved in the remodeling of the extracellular matrix
0.0 2.5 WNT SIGNALING Genes related to Wnt-mediated signal transduction
0.0 1.5 PID MTOR 4PATHWAY mTOR signaling pathway
0.0 3.5 NABA ECM GLYCOPROTEINS Genes encoding structural ECM glycoproteins
0.0 1.4 PID TRKR PATHWAY Neurotrophic factor-mediated Trk receptor signaling
0.0 0.4 PID FRA PATHWAY Validated transcriptional targets of AP1 family members Fra1 and Fra2
0.0 1.4 PID AR PATHWAY Coregulation of Androgen receptor activity
0.0 0.3 PID IL2 PI3K PATHWAY IL2 signaling events mediated by PI3K
0.0 0.7 PID ILK PATHWAY Integrin-linked kinase signaling
0.0 0.3 PID CD8 TCR DOWNSTREAM PATHWAY Downstream signaling in naïve CD8+ T cells
0.0 0.4 NABA PROTEOGLYCANS Genes encoding proteoglycans

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.8 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.2 3.2 REACTOME CLASS C 3 METABOTROPIC GLUTAMATE PHEROMONE RECEPTORS Genes involved in Class C/3 (Metabotropic glutamate/pheromone receptors)
0.2 3.6 REACTOME NA CL DEPENDENT NEUROTRANSMITTER TRANSPORTERS Genes involved in Na+/Cl- dependent neurotransmitter transporters
0.1 2.8 REACTOME RAS ACTIVATION UOPN CA2 INFUX THROUGH NMDA RECEPTOR Genes involved in Ras activation uopn Ca2+ infux through NMDA receptor
0.1 1.8 REACTOME PLATELET CALCIUM HOMEOSTASIS Genes involved in Platelet calcium homeostasis
0.1 1.5 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.1 1.3 REACTOME TRAFFICKING OF GLUR2 CONTAINING AMPA RECEPTORS Genes involved in Trafficking of GluR2-containing AMPA receptors
0.0 1.9 REACTOME STEROID HORMONES Genes involved in Steroid hormones
0.0 1.8 REACTOME SPHINGOLIPID DE NOVO BIOSYNTHESIS Genes involved in Sphingolipid de novo biosynthesis
0.0 0.7 REACTOME NOTCH HLH TRANSCRIPTION PATHWAY Genes involved in Notch-HLH transcription pathway
0.0 0.8 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease
0.0 0.9 REACTOME NUCLEOTIDE LIKE PURINERGIC RECEPTORS Genes involved in Nucleotide-like (purinergic) receptors
0.0 0.9 REACTOME CYCLIN E ASSOCIATED EVENTS DURING G1 S TRANSITION Genes involved in Cyclin E associated events during G1/S transition
0.0 0.5 REACTOME SYNTHESIS OF PIPS AT THE LATE ENDOSOME MEMBRANE Genes involved in Synthesis of PIPs at the late endosome membrane
0.0 0.5 REACTOME RNA POL III CHAIN ELONGATION Genes involved in RNA Polymerase III Chain Elongation
0.0 0.3 REACTOME TGF BETA RECEPTOR SIGNALING IN EMT EPITHELIAL TO MESENCHYMAL TRANSITION Genes involved in TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)
0.0 0.5 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.0 1.0 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 1.0 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.7 REACTOME SHC1 EVENTS IN ERBB4 SIGNALING Genes involved in SHC1 events in ERBB4 signaling
0.0 0.8 REACTOME MEIOTIC SYNAPSIS Genes involved in Meiotic Synapsis
0.0 0.3 REACTOME GLUCAGON TYPE LIGAND RECEPTORS Genes involved in Glucagon-type ligand receptors
0.0 0.2 REACTOME DOWNSTREAM SIGNAL TRANSDUCTION Genes involved in Downstream signal transduction
0.0 0.3 REACTOME REGULATION OF IFNA SIGNALING Genes involved in Regulation of IFNA signaling
0.0 0.6 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.3 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.2 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.5 REACTOME REGULATION OF BETA CELL DEVELOPMENT Genes involved in Regulation of beta-cell development
0.0 0.3 REACTOME SIGNALING BY NODAL Genes involved in Signaling by NODAL