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avrg: GFI1 WT vs 36n/n vs KD

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Results for Erg

Z-value: 1.64

Motif logo

Transcription factors associated with Erg

Gene Symbol Gene ID Gene Info
ENSMUSG00000040732.21 ETS transcription factor

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Ergmm39_v1_chr16_-_95387444_95387454-0.583.0e-01Click!

Activity profile of Erg motif

Sorted Z-values of Erg motif

Promoter Log-likelihood Transcript Gene Gene Info
chr9_+_123195986 2.18 ENSMUST00000038863.9
ENSMUST00000216843.2
leucyl-tRNA synthetase, mitochondrial
chr1_+_16758629 1.42 ENSMUST00000026881.11
lymphocyte antigen 96
chr5_+_90907207 1.28 ENSMUST00000031318.6
chemokine (C-X-C motif) ligand 5
chr6_+_42326714 1.11 ENSMUST00000203846.3
zyxin
chr6_-_146403410 0.99 ENSMUST00000053273.15
inositol 1,4,5-triphosphate receptor 2
chr10_-_95159933 0.99 ENSMUST00000053594.7
CASP2 and RIPK1 domain containing adaptor with death domain
chr1_+_131936022 0.99 ENSMUST00000146432.2
ELK4, member of ETS oncogene family
chr6_-_97408367 0.95 ENSMUST00000124050.3
FERM domain containing 4B
chr16_-_4698148 0.93 ENSMUST00000037843.7
UBA-like domain containing 1
chr14_+_51366512 0.86 ENSMUST00000095923.4
ribonuclease, RNase A family, 6
chr7_+_75351713 0.84 ENSMUST00000207239.2
A kinase (PRKA) anchor protein 13
chr2_+_164897547 0.83 ENSMUST00000017799.12
ENSMUST00000073707.9
CD40 antigen
chr14_-_32907446 0.82 ENSMUST00000159606.2
WD repeat and FYVE domain containing 4
chr16_-_48592372 0.79 ENSMUST00000231701.3
T cell receptor associated transmembrane adaptor 1
chr2_+_28095660 0.78 ENSMUST00000102879.4
ENSMUST00000028177.11
olfactomedin 1
chr8_-_123768984 0.77 ENSMUST00000212937.2
ankyrin repeat domain 11
chr11_-_103254257 0.76 ENSMUST00000092557.6
Rho GTPase activating protein 27
chr19_+_8828132 0.76 ENSMUST00000235683.2
ENSMUST00000096257.3
LRRN4 C-terminal like
chr6_+_42326980 0.76 ENSMUST00000203849.2
zyxin
chr14_+_20732804 0.74 ENSMUST00000228545.2
Sec24 related gene family, member C (S. cerevisiae)
chr15_-_82783978 0.74 ENSMUST00000230403.2
transcription factor 20
chr11_-_69586626 0.74 ENSMUST00000108649.3
ENSMUST00000174159.8
ENSMUST00000181810.8
tumor necrosis factor (ligand) superfamily, membrane-bound member 13
tumor necrosis factor (ligand) superfamily, member 12
chr3_-_122778052 0.72 ENSMUST00000199401.2
ENSMUST00000197314.5
ENSMUST00000197934.5
ENSMUST00000090379.7
ubiquitin specific peptidase 53
chr12_-_31549538 0.72 ENSMUST00000064240.14
ENSMUST00000185739.8
ENSMUST00000188326.3
ENSMUST00000101499.10
ENSMUST00000085487.12
Casitas B-lineage lymphoma-like 1
chr11_+_116324913 0.72 ENSMUST00000057676.7
UBA-like domain containing 2
chr6_+_42326934 0.71 ENSMUST00000203401.3
ENSMUST00000164375.4
zyxin
chr6_+_42326760 0.70 ENSMUST00000203652.3
ENSMUST00000070635.13
zyxin
chr7_+_130375799 0.69 ENSMUST00000048453.7
ENSMUST00000208593.2
BTB (POZ) domain containing 16
chr2_+_129854256 0.68 ENSMUST00000110299.3
transglutaminase 3, E polypeptide
chr9_-_43027809 0.65 ENSMUST00000216126.2
ENSMUST00000213544.2
ENSMUST00000061833.6
TLC domain containing 5
chr3_+_135143910 0.64 ENSMUST00000196446.5
ENSMUST00000106291.10
ENSMUST00000199613.5
ubiquitin-conjugating enzyme E2D 3
chr4_+_8690398 0.63 ENSMUST00000127476.8
chromodomain helicase DNA binding protein 7
chr14_+_51366306 0.63 ENSMUST00000226210.2
ribonuclease, RNase A family, 6
chr17_-_32503107 0.62 ENSMUST00000237692.2
bromodomain containing 4
chr7_+_126365506 0.62 ENSMUST00000032944.9
glycerophosphodiester phosphodiesterase domain containing 3
chr2_-_5719302 0.62 ENSMUST00000044009.14
calcium/calmodulin-dependent protein kinase ID
chr2_+_32536594 0.62 ENSMUST00000113272.8
ENSMUST00000009705.14
ENSMUST00000167841.8
endoglin
chr15_-_76079891 0.60 ENSMUST00000023226.13
plectin
chr2_-_91854844 0.60 ENSMUST00000028663.5
cAMP responsive element binding protein 3-like 1
chrX_-_156198282 0.59 ENSMUST00000079945.11
ENSMUST00000138396.3
phosphate regulating endopeptidase homolog, X-linked
chr15_-_64254754 0.57 ENSMUST00000177374.8
ENSMUST00000110114.10
ENSMUST00000110115.9
ENSMUST00000023008.16
ArfGAP with SH3 domain, ankyrin repeat and PH domain1
chr2_-_73284262 0.56 ENSMUST00000102679.8
WAS/WASL interacting protein family, member 1
chr17_-_45046499 0.56 ENSMUST00000162373.8
ENSMUST00000162878.8
runt related transcription factor 2
chr11_+_32483290 0.54 ENSMUST00000102821.4
serine/threonine kinase 10
chr17_-_32503060 0.54 ENSMUST00000003726.16
ENSMUST00000121285.8
ENSMUST00000120276.9
bromodomain containing 4
chr3_+_135144304 0.54 ENSMUST00000198685.5
ENSMUST00000197859.5
ubiquitin-conjugating enzyme E2D 3
chrX_-_9335525 0.54 ENSMUST00000015484.10
cytochrome b-245, beta polypeptide
chr1_+_34044940 0.53 ENSMUST00000187486.7
ENSMUST00000182697.8
dystonin
chr4_-_63321591 0.53 ENSMUST00000035724.5
AT-hook transcription factor
chr16_+_51851948 0.53 ENSMUST00000226593.2
Casitas B-lineage lymphoma b
chr8_-_106052884 0.52 ENSMUST00000210412.2
ENSMUST00000210801.2
ENSMUST00000070508.8
leucine rich repeat containing 29
chr9_-_110305705 0.51 ENSMUST00000198164.5
ENSMUST00000068025.13
kelch-like 18
chr7_-_30741762 0.51 ENSMUST00000161684.8
FXYD domain-containing ion transport regulator 5
chr6_-_99073156 0.50 ENSMUST00000175886.8
forkhead box P1
chr16_+_57369595 0.50 ENSMUST00000159414.2
filamin A interacting protein 1-like
chr17_+_33857030 0.50 ENSMUST00000052079.8
PML-RAR alpha-regulated adaptor molecule 1
chr13_-_115238427 0.49 ENSMUST00000224997.2
ENSMUST00000061673.9
predicted gene, 49395
integrin alpha 1
chr16_+_51851917 0.48 ENSMUST00000227062.2
Casitas B-lineage lymphoma b
chr1_+_16758731 0.48 ENSMUST00000190366.2
lymphocyte antigen 96
chr12_+_76580386 0.48 ENSMUST00000219063.2
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr2_-_92290054 0.47 ENSMUST00000136718.2
solute carrier family 35, member C1
chr11_+_113548201 0.47 ENSMUST00000148736.8
ENSMUST00000142069.8
ENSMUST00000134418.8
component of oligomeric golgi complex 1
chrX_+_162691978 0.46 ENSMUST00000069041.15
adaptor-related protein complex 1, sigma 2 subunit
chr2_-_101627999 0.46 ENSMUST00000171088.8
ENSMUST00000043845.14
proline rich 5 like
chr15_-_80989200 0.45 ENSMUST00000109579.9
myocardin related transcription factor A
chr13_-_41640757 0.45 ENSMUST00000021794.14
neural precursor cell expressed, developmentally down-regulated gene 9
chr9_-_114325630 0.45 ENSMUST00000054414.5
chemokine (C-C motif) receptor 4
chr3_-_52012462 0.45 ENSMUST00000121440.4
mastermind like transcriptional coactivator 3
chr9_+_110306052 0.45 ENSMUST00000197248.5
ENSMUST00000061155.12
ENSMUST00000198043.5
ENSMUST00000084952.8
kinesin family member 9
chr7_-_30741532 0.45 ENSMUST00000160689.8
ENSMUST00000202395.4
ENSMUST00000162733.8
ENSMUST00000162087.8
ENSMUST00000009831.14
FXYD domain-containing ion transport regulator 5
chr6_-_83433357 0.45 ENSMUST00000186548.7
tet methylcytosine dioxygenase 3
chr1_+_171668122 0.44 ENSMUST00000135386.2
CD84 antigen
chr1_+_17672117 0.44 ENSMUST00000088476.4
peptidase inhibitor 15
chr10_-_12689345 0.44 ENSMUST00000217899.2
utrophin
chr16_+_43993599 0.44 ENSMUST00000119746.8
ENSMUST00000088356.10
ENSMUST00000169582.3
upstream transcription factor family member 3
chr8_-_123768759 0.44 ENSMUST00000098334.13
ankyrin repeat domain 11
chr2_+_61423469 0.44 ENSMUST00000112494.2
TRAF family member-associated Nf-kappa B activator
chr12_+_37292029 0.43 ENSMUST00000160390.2
alkylglycerol monooxygenase
chr9_+_38119661 0.43 ENSMUST00000211975.3
olfactory receptor 893
chr10_-_68114543 0.43 ENSMUST00000219238.2
AT rich interactive domain 5B (MRF1-like)
chr12_+_76593799 0.42 ENSMUST00000218380.2
ENSMUST00000219751.2
pleckstrin homology domain containing, family G (with RhoGef domain) member 3
chr14_-_122153185 0.42 ENSMUST00000055475.9
G protein-coupled receptor 18
chr3_+_90511068 0.42 ENSMUST00000001046.7
S100 calcium binding protein A4
chr6_-_131224305 0.42 ENSMUST00000032306.15
ENSMUST00000088867.7
killer cell lectin-like receptor, subfamily A, member 2
chr9_-_37259664 0.41 ENSMUST00000216042.2
ENSMUST00000239439.2
ENSMUST00000037275.6
coiled-coil domain containing 15
chr14_-_55909314 0.41 ENSMUST00000163750.8
neural precursor cell expressed, developmentally down-regulated gene 8
chr6_+_42326528 0.41 ENSMUST00000203329.3
zyxin
chr7_-_30741512 0.40 ENSMUST00000159753.2
FXYD domain-containing ion transport regulator 5
chr7_-_46569617 0.40 ENSMUST00000210664.2
ENSMUST00000156335.9
tumor susceptibility gene 101
chr16_+_44586085 0.40 ENSMUST00000057488.15
CD200 receptor 1
chr14_-_19261196 0.40 ENSMUST00000112797.12
ENSMUST00000225885.2
RIKEN cDNA D830030K20 gene
chr6_-_146403638 0.40 ENSMUST00000079573.13
inositol 1,4,5-triphosphate receptor 2
chr13_+_41040657 0.39 ENSMUST00000069958.15
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme
chr2_+_145627900 0.39 ENSMUST00000110005.8
ENSMUST00000094480.11
Ras and Rab interactor 2
chr2_-_121211410 0.39 ENSMUST00000038389.15
stereocilin
chr13_+_120085355 0.39 ENSMUST00000099241.4
chemokine (C-C motif) ligand 28
chr9_-_37259690 0.39 ENSMUST00000213633.2
coiled-coil domain containing 15
chr2_-_26012751 0.38 ENSMUST00000140993.2
ENSMUST00000028300.6
nucleus accumbens associated 2, BEN and BTB (POZ) domain containing
chr12_+_102249294 0.38 ENSMUST00000056950.14
Ras and Rab interactor 3
chrX_+_137815171 0.38 ENSMUST00000064937.14
ENSMUST00000113052.8
Nik related kinase
chr16_+_62635039 0.38 ENSMUST00000055557.6
syntaxin 19
chr11_-_69586884 0.38 ENSMUST00000180587.8
tumor necrosis factor (ligand) superfamily, membrane-bound member 13
chrX_+_109857866 0.38 ENSMUST00000078229.5
POU domain, class 3, transcription factor 4
chr13_+_109397184 0.38 ENSMUST00000153234.8
phosphodiesterase 4D, cAMP specific
chr11_+_29324348 0.38 ENSMUST00000239407.2
coiled coil domain containing 88A
chr19_+_44191704 0.37 ENSMUST00000026220.7
stearoyl-coenzyme A desaturase 3
chr14_-_31157985 0.37 ENSMUST00000091903.5
SH3-domain binding protein 5 (BTK-associated)
chrX_+_158410229 0.37 ENSMUST00000112456.9
SH3-domain kinase binding protein 1
chr2_+_91480513 0.37 ENSMUST00000090614.11
Rho GTPase activating protein 1
chr11_+_117545037 0.37 ENSMUST00000026658.13
trinucleotide repeat containing 6C
chr19_+_6413703 0.36 ENSMUST00000131252.8
ENSMUST00000113489.8
splicing factor 1
chr7_-_46569662 0.36 ENSMUST00000143413.3
ENSMUST00000014546.15
tumor susceptibility gene 101
chr8_+_84852609 0.36 ENSMUST00000093380.5
podocan-like 1
chr1_-_39517761 0.36 ENSMUST00000193823.2
ENSMUST00000054462.11
TBC1 domain family, member 8
chr3_+_124114504 0.36 ENSMUST00000058994.6
translocation associated membrane protein 1-like 1
chr7_-_115933367 0.35 ENSMUST00000205490.2
ENSMUST00000170953.3
ribosomal protein S13
chr3_-_137687284 0.35 ENSMUST00000136613.4
ENSMUST00000029806.13
dual adaptor for phosphotyrosine and 3-phosphoinositides 1
chr12_+_33365371 0.35 ENSMUST00000154742.2
ataxin 7-like 1
chr16_+_55895786 0.35 ENSMUST00000049128.11
ENSMUST00000089362.9
ENSMUST00000202799.4
ENSMUST00000201011.2
ENSMUST00000202000.2
SUMO1/sentrin specific peptidase 7
chr4_-_116413092 0.34 ENSMUST00000069674.6
ENSMUST00000106478.9
transmembrane protein 69
chr15_-_76501525 0.34 ENSMUST00000230977.2
solute carrier family 39 (zinc transporter), member 4
chr12_+_102249375 0.34 ENSMUST00000101114.11
ENSMUST00000150795.8
Ras and Rab interactor 3
chr14_-_55909527 0.34 ENSMUST00000010520.10
neural precursor cell expressed, developmentally down-regulated gene 8
chr5_+_29940935 0.34 ENSMUST00000114839.8
ENSMUST00000198694.5
ENSMUST00000012734.10
ENSMUST00000196528.5
DnaJ heat shock protein family (Hsp40) member B6
chr11_-_119246310 0.34 ENSMUST00000100172.3
ENSMUST00000005173.11
N-sulfoglucosamine sulfohydrolase (sulfamidase)
chr1_-_156301821 0.33 ENSMUST00000188027.2
ENSMUST00000187507.7
ENSMUST00000189661.7
sterol O-acyltransferase 1
chr8_+_3543131 0.33 ENSMUST00000061508.8
ENSMUST00000207318.2
zinc finger protein 358
chrX_-_12628309 0.33 ENSMUST00000096495.11
ENSMUST00000076016.6
mediator complex subunit 14
chr5_-_31684036 0.33 ENSMUST00000202421.2
ENSMUST00000201769.4
ENSMUST00000065388.11
SPT7-like, STAGA complex gamma subunit
chr4_+_125918333 0.33 ENSMUST00000106162.8
colony stimulating factor 3 receptor (granulocyte)
chr3_+_135144202 0.33 ENSMUST00000166033.6
ubiquitin-conjugating enzyme E2D 3
chrX_+_162692126 0.33 ENSMUST00000033734.14
ENSMUST00000112294.9
adaptor-related protein complex 1, sigma 2 subunit
chr11_-_79421397 0.33 ENSMUST00000103236.4
ENSMUST00000170799.8
ENSMUST00000170422.4
ecotropic viral integration site 2a
ecotropic viral integration site 2
chr16_+_51851588 0.32 ENSMUST00000114471.3
Casitas B-lineage lymphoma b
chr17_+_86475205 0.32 ENSMUST00000097275.9
protein kinase C, epsilon
chr7_+_135139542 0.32 ENSMUST00000073961.8
protein tyrosine phosphatase, receptor type, E
chr5_-_86666408 0.32 ENSMUST00000140095.2
ENSMUST00000134179.8
transmembrane protease, serine 11g
chr6_-_122317156 0.32 ENSMUST00000159384.8
polyhomeotic 1
chr7_-_30741237 0.31 ENSMUST00000161805.8
FXYD domain-containing ion transport regulator 5
chr2_-_86882616 0.31 ENSMUST00000213781.2
ENSMUST00000217650.2
olfactory receptor 1106
chrX_+_158623460 0.31 ENSMUST00000112451.8
ENSMUST00000112453.9
SH3-domain kinase binding protein 1
chr2_+_48839505 0.31 ENSMUST00000112745.8
ENSMUST00000112754.8
methyl-CpG binding domain protein 5
chr7_-_30741497 0.31 ENSMUST00000162116.8
ENSMUST00000159924.8
FXYD domain-containing ion transport regulator 5
chr19_-_12302465 0.31 ENSMUST00000207241.3
olfactory receptor 1437
chr12_-_84240781 0.31 ENSMUST00000110294.2
mitotic deacetylase associated SANT domain protein
chr1_-_80642969 0.31 ENSMUST00000190983.7
ENSMUST00000191449.2
dedicator of cytokinesis 10
chrX_+_158410528 0.30 ENSMUST00000073094.10
SH3-domain kinase binding protein 1
chr6_-_52190299 0.30 ENSMUST00000128102.4
predicted gene 28308
chr2_+_91480460 0.30 ENSMUST00000111331.9
Rho GTPase activating protein 1
chr8_+_108020132 0.30 ENSMUST00000151114.8
ENSMUST00000125721.8
ENSMUST00000075922.11
nuclear factor of activated T cells 5
chr17_-_59320257 0.29 ENSMUST00000174122.2
ENSMUST00000025065.12
nudix (nucleoside diphosphate linked moiety X)-type motif 12
chr2_-_180776920 0.29 ENSMUST00000197015.5
ENSMUST00000103050.10
ENSMUST00000081528.13
ENSMUST00000049792.15
ENSMUST00000103048.10
ENSMUST00000103047.10
ENSMUST00000149964.9
potassium voltage-gated channel, subfamily Q, member 2
chr2_-_92290128 0.29 ENSMUST00000067631.7
solute carrier family 35, member C1
chr11_+_70538083 0.29 ENSMUST00000037534.8
ring finger protein 167
chr1_+_138891155 0.29 ENSMUST00000200533.5
DENN/MADD domain containing 1B
chr4_+_129229373 0.29 ENSMUST00000141235.8
zinc finger and BTB domain containing 8 opposite strand
chr11_-_104441218 0.29 ENSMUST00000106962.9
ENSMUST00000106961.2
ENSMUST00000093923.9
cell division cycle 27
chr11_+_117545618 0.29 ENSMUST00000106344.8
trinucleotide repeat containing 6C
chr3_+_135144287 0.29 ENSMUST00000196591.5
ubiquitin-conjugating enzyme E2D 3
chr2_-_22930149 0.29 ENSMUST00000091394.13
ENSMUST00000093171.13
abl interactor 1
chr8_+_120163857 0.28 ENSMUST00000152420.8
ENSMUST00000212112.2
ENSMUST00000098365.4
oxidative stress induced growth inhibitor 1
chr4_-_122779837 0.28 ENSMUST00000106255.8
ENSMUST00000106257.10
CAP, adenylate cyclase-associated protein 1 (yeast)
chr16_+_84631789 0.28 ENSMUST00000114184.8
GA repeat binding protein, alpha
chr3_+_27237143 0.28 ENSMUST00000091284.5
neutral cholesterol ester hydrolase 1
chr7_+_135253659 0.28 ENSMUST00000209979.2
protein tyrosine phosphatase, receptor type, E
chr13_-_110493665 0.27 ENSMUST00000058806.7
ENSMUST00000224534.2
Grb2-binding adaptor, transmembrane
chr17_+_75742881 0.27 ENSMUST00000164192.9
RAS, guanyl releasing protein 3
chr14_-_100521888 0.27 ENSMUST00000226774.2
Kruppel-like factor 12
chr7_+_127475968 0.27 ENSMUST00000131000.2
zinc finger protein 646
chr16_+_95058417 0.27 ENSMUST00000113861.8
ENSMUST00000113854.8
ENSMUST00000113862.8
ENSMUST00000037154.14
ENSMUST00000113855.8
potassium inwardly-rectifying channel, subfamily J, member 15
chr10_-_81335966 0.27 ENSMUST00000053646.7
sphingosine-1-phosphate receptor 4
chr18_+_23937019 0.27 ENSMUST00000025127.5
microtubule-associated protein, RP/EB family, member 2
chr10_-_80895949 0.27 ENSMUST00000219401.2
ENSMUST00000220317.2
ENSMUST00000005067.6
ENSMUST00000218208.2
small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
chr2_+_129434738 0.27 ENSMUST00000153491.8
ENSMUST00000161620.8
ENSMUST00000179001.8
signal-regulatory protein alpha
chr13_+_41013230 0.27 ENSMUST00000110191.10
glucosaminyl (N-acetyl) transferase 2, I-branching enzyme
chr2_-_27317004 0.26 ENSMUST00000056176.8
vav 2 oncogene
chr6_-_122316547 0.26 ENSMUST00000161210.3
ENSMUST00000161054.8
ENSMUST00000159252.8
ENSMUST00000161739.8
ENSMUST00000161149.8
polyhomeotic 1
chr13_-_104056803 0.26 ENSMUST00000091269.11
ENSMUST00000188997.7
ENSMUST00000169083.8
ENSMUST00000191275.7
Erbb2 interacting protein
chr2_+_120398133 0.26 ENSMUST00000110711.9
synaptosomal-associated protein 23
chr9_+_123901979 0.26 ENSMUST00000171719.8
chemokine (C-C motif) receptor 2
chr17_-_29226886 0.26 ENSMUST00000232723.2
serine/threonine kinase 38
chr1_+_55445033 0.26 ENSMUST00000042986.10
phospholipase C-like 1
chr3_-_90120942 0.26 ENSMUST00000195998.5
ENSMUST00000197361.5
ENSMUST00000170122.4
ribosomal protein S27
chr7_+_135139568 0.26 ENSMUST00000209256.2
protein tyrosine phosphatase, receptor type, E
chr5_-_36987917 0.25 ENSMUST00000031002.10
mannosidase 2, alpha B2
chr15_-_66432938 0.25 ENSMUST00000048372.7
transmembrane protein 71
chr3_-_57599956 0.25 ENSMUST00000238789.2
ENSMUST00000197088.5
ENSMUST00000099091.4
ankrin repeat and ubiquitin domain containing 1
chr3_+_103767581 0.25 ENSMUST00000029433.9
protein tyrosine phosphatase, non-receptor type 22 (lymphoid)
chr3_+_96484294 0.25 ENSMUST00000148290.2
predicted gene 16253
chr3_-_105839980 0.25 ENSMUST00000098758.5
RIKEN cDNA I830077J02 gene
chr2_+_129434834 0.25 ENSMUST00000103203.8
signal-regulatory protein alpha
chr15_-_28025920 0.25 ENSMUST00000090247.7
triple functional domain (PTPRF interacting)
chr10_+_115220826 0.25 ENSMUST00000036044.9
zinc finger, C3H1-type containing
chr3_+_45332831 0.25 ENSMUST00000193252.2
ENSMUST00000171554.8
ENSMUST00000166126.7
ENSMUST00000170695.4
protocadherin 10
chrX_-_142716200 0.25 ENSMUST00000112851.8
ENSMUST00000112856.3
ENSMUST00000033642.10
doublecortin
chr11_+_101207021 0.25 ENSMUST00000142640.8
ENSMUST00000019470.14
proteaseome (prosome, macropain) activator subunit 3 (PA28 gamma, Ki)
chr17_+_17669082 0.25 ENSMUST00000140134.2
limb and CNS expressed 1
chr4_+_43730034 0.24 ENSMUST00000131248.2
small regulatory polypeptide of amino acid response
chr11_-_4110286 0.24 ENSMUST00000093381.11
ENSMUST00000101626.9
coiled-coil domain containing 157
chr16_+_43184191 0.24 ENSMUST00000156367.8
zinc finger and BTB domain containing 20

Network of associatons between targets according to the STRING database.

First level regulatory network of Erg

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.2 GO:0006429 leucyl-tRNA aminoacylation(GO:0006429)
0.4 1.3 GO:0070949 regulation of neutrophil mediated cytotoxicity(GO:0070948) regulation of neutrophil mediated killing of symbiont cell(GO:0070949)
0.3 1.9 GO:0032497 detection of lipopolysaccharide(GO:0032497)
0.3 1.0 GO:0007185 transmembrane receptor protein tyrosine phosphatase signaling pathway(GO:0007185)
0.2 1.2 GO:0070278 extracellular matrix constituent secretion(GO:0070278)
0.2 0.8 GO:2000397 regulation of ubiquitin-dependent endocytosis(GO:2000395) positive regulation of ubiquitin-dependent endocytosis(GO:2000397)
0.2 0.6 GO:0003221 right ventricular cardiac muscle tissue morphogenesis(GO:0003221)
0.1 0.4 GO:0002304 gamma-delta intraepithelial T cell differentiation(GO:0002304) CD8-positive, gamma-delta intraepithelial T cell differentiation(GO:0002305)
0.1 1.4 GO:0002913 positive regulation of T cell anergy(GO:0002669) positive regulation of lymphocyte anergy(GO:0002913)
0.1 0.1 GO:0038189 neuropilin signaling pathway(GO:0038189) VEGF-activated neuropilin signaling pathway(GO:0038190)
0.1 0.4 GO:0032685 negative regulation of granulocyte macrophage colony-stimulating factor production(GO:0032685)
0.1 0.8 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.1 0.4 GO:1900477 negative regulation of G1/S transition of mitotic cell cycle by negative regulation of transcription from RNA polymerase II promoter(GO:1900477)
0.1 0.4 GO:0060722 spongiotrophoblast cell proliferation(GO:0060720) cell proliferation involved in embryonic placenta development(GO:0060722)
0.1 0.4 GO:0090264 immune complex clearance by monocytes and macrophages(GO:0002436) regulation of immune complex clearance by monocytes and macrophages(GO:0090264) positive regulation of immune complex clearance by monocytes and macrophages(GO:0090265) negative regulation of eosinophil activation(GO:1902567) positive regulation of CD8-positive, alpha-beta T cell extravasation(GO:2000451)
0.1 0.8 GO:1903527 positive regulation of membrane tubulation(GO:1903527)
0.1 0.3 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.1 0.3 GO:0042986 positive regulation of amyloid precursor protein biosynthetic process(GO:0042986)
0.1 0.7 GO:0032439 endosome localization(GO:0032439) negative regulation of vacuolar transport(GO:1903336)
0.1 0.4 GO:2000158 positive regulation of ubiquitin-specific protease activity(GO:2000158)
0.1 0.6 GO:0070433 negative regulation of nucleotide-binding oligomerization domain containing signaling pathway(GO:0070425) negative regulation of nucleotide-binding oligomerization domain containing 2 signaling pathway(GO:0070433)
0.1 0.6 GO:0002322 B cell proliferation involved in immune response(GO:0002322)
0.1 0.8 GO:0071883 activation of MAPK activity by adrenergic receptor signaling pathway(GO:0071883)
0.1 0.3 GO:0060715 syncytiotrophoblast cell differentiation involved in labyrinthine layer development(GO:0060715)
0.1 1.5 GO:0071361 cellular response to ethanol(GO:0071361)
0.1 0.4 GO:1903237 negative regulation of leukocyte tethering or rolling(GO:1903237)
0.1 0.7 GO:0036438 maintenance of lens transparency(GO:0036438)
0.1 0.4 GO:0044727 DNA demethylation of male pronucleus(GO:0044727)
0.1 0.2 GO:0002545 chronic inflammatory response to non-antigenic stimulus(GO:0002545) regulation of chronic inflammatory response to non-antigenic stimulus(GO:0002880)
0.1 0.3 GO:0060399 positive regulation of growth hormone receptor signaling pathway(GO:0060399)
0.1 1.2 GO:0044154 histone H3-K14 acetylation(GO:0044154)
0.1 0.3 GO:0035880 embryonic nail plate morphogenesis(GO:0035880)
0.1 0.5 GO:0007527 adult somatic muscle development(GO:0007527)
0.1 0.2 GO:0007386 compartment pattern specification(GO:0007386)
0.1 0.2 GO:0071640 regulation of macrophage inflammatory protein 1 alpha production(GO:0071640)
0.1 0.3 GO:1901355 response to rapamycin(GO:1901355)
0.1 0.3 GO:0034224 cellular response to zinc ion starvation(GO:0034224)
0.1 0.4 GO:1903964 monounsaturated fatty acid metabolic process(GO:1903964) monounsaturated fatty acid biosynthetic process(GO:1903966)
0.1 0.5 GO:0097411 hypoxia-inducible factor-1alpha signaling pathway(GO:0097411)
0.1 0.3 GO:1903070 negative regulation of ER-associated ubiquitin-dependent protein catabolic process(GO:1903070)
0.1 0.8 GO:0023041 neuronal signal transduction(GO:0023041)
0.1 0.3 GO:0071336 regulation of hair follicle cell proliferation(GO:0071336)
0.1 0.2 GO:0044878 mitotic cytokinesis checkpoint(GO:0044878)
0.1 0.9 GO:0090037 positive regulation of protein kinase C signaling(GO:0090037)
0.1 0.4 GO:1903566 positive regulation of protein localization to cilium(GO:1903566)
0.1 0.6 GO:0060267 positive regulation of respiratory burst(GO:0060267)
0.1 0.2 GO:0001807 regulation of type IV hypersensitivity(GO:0001807)
0.1 1.0 GO:0030259 lipid glycosylation(GO:0030259)
0.1 0.2 GO:2000588 positive regulation of platelet-derived growth factor receptor-beta signaling pathway(GO:2000588)
0.1 0.8 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.1 0.5 GO:0032625 interleukin-21 production(GO:0032625) interleukin-21 secretion(GO:0072619)
0.1 0.2 GO:1903904 negative regulation of establishment of T cell polarity(GO:1903904)
0.1 1.0 GO:0006977 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest(GO:0006977)
0.1 0.3 GO:1900122 positive regulation of receptor binding(GO:1900122)
0.1 0.2 GO:0002625 regulation of T cell antigen processing and presentation(GO:0002625)
0.1 2.1 GO:0070979 protein K11-linked ubiquitination(GO:0070979)
0.1 0.6 GO:0002051 osteoblast fate commitment(GO:0002051)
0.0 0.4 GO:0038203 TORC2 signaling(GO:0038203)
0.0 0.5 GO:0098881 exocytic insertion of neurotransmitter receptor to plasma membrane(GO:0098881) exocytic insertion of neurotransmitter receptor to postsynaptic membrane(GO:0098967)
0.0 0.2 GO:0045347 negative regulation of MHC class II biosynthetic process(GO:0045347)
0.0 0.1 GO:0021759 globus pallidus development(GO:0021759)
0.0 0.7 GO:0070932 histone H3 deacetylation(GO:0070932)
0.0 0.2 GO:0016584 nucleosome positioning(GO:0016584)
0.0 0.2 GO:0034635 glutathione transport(GO:0034635) tripeptide transport(GO:0042939)
0.0 0.5 GO:0007221 positive regulation of transcription of Notch receptor target(GO:0007221)
0.0 0.7 GO:0035278 miRNA mediated inhibition of translation(GO:0035278) negative regulation of translation, ncRNA-mediated(GO:0040033) regulation of translation, ncRNA-mediated(GO:0045974)
0.0 0.2 GO:0052151 positive regulation by symbiont of host apoptotic process(GO:0052151) positive regulation of apoptotic process by virus(GO:0060139)
0.0 0.6 GO:0031581 hemidesmosome assembly(GO:0031581)
0.0 0.3 GO:0032667 interleukin-23 production(GO:0032627) regulation of interleukin-23 production(GO:0032667)
0.0 0.4 GO:0002315 marginal zone B cell differentiation(GO:0002315)
0.0 0.1 GO:0048022 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.0 0.1 GO:1904828 regulation of hydrogen sulfide biosynthetic process(GO:1904826) positive regulation of hydrogen sulfide biosynthetic process(GO:1904828)
0.0 0.2 GO:0035752 lysosomal lumen pH elevation(GO:0035752)
0.0 0.1 GO:1902277 negative regulation of pancreatic amylase secretion(GO:1902277)
0.0 0.1 GO:0051866 general adaptation syndrome(GO:0051866)
0.0 0.1 GO:0000389 mRNA 3'-splice site recognition(GO:0000389)
0.0 0.5 GO:0060613 fat pad development(GO:0060613)
0.0 0.1 GO:1904274 tricellular tight junction assembly(GO:1904274)
0.0 0.3 GO:0050882 voluntary musculoskeletal movement(GO:0050882)
0.0 0.1 GO:1905076 regulation of interleukin-17 secretion(GO:1905076)
0.0 1.1 GO:0019731 antibacterial humoral response(GO:0019731)
0.0 0.1 GO:1900110 negative regulation of histone H3-K9 dimethylation(GO:1900110)
0.0 0.1 GO:0061534 gamma-aminobutyric acid secretion, neurotransmission(GO:0061534)
0.0 0.2 GO:0034334 adherens junction maintenance(GO:0034334)
0.0 0.1 GO:0043323 positive regulation of natural killer cell degranulation(GO:0043323)
0.0 0.4 GO:0046485 ether lipid metabolic process(GO:0046485)
0.0 0.1 GO:0045659 negative regulation of neutrophil differentiation(GO:0045659)
0.0 0.2 GO:0090383 phagosome acidification(GO:0090383)
0.0 0.2 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.0 0.6 GO:0090110 cargo loading into COPII-coated vesicle(GO:0090110)
0.0 0.2 GO:0070173 regulation of enamel mineralization(GO:0070173)
0.0 0.2 GO:0070933 histone H4 deacetylation(GO:0070933)
0.0 0.1 GO:1904092 regulation of autophagic cell death(GO:1904092) negative regulation of autophagic cell death(GO:1904093)
0.0 0.4 GO:0099500 synaptic vesicle fusion to presynaptic active zone membrane(GO:0031629) vesicle fusion to plasma membrane(GO:0099500)
0.0 0.3 GO:2000675 negative regulation of type B pancreatic cell apoptotic process(GO:2000675)
0.0 0.3 GO:1903350 response to dopamine(GO:1903350) cellular response to dopamine(GO:1903351)
0.0 0.1 GO:0006168 adenine salvage(GO:0006168) adenine metabolic process(GO:0046083) adenine biosynthetic process(GO:0046084)
0.0 0.1 GO:0071579 regulation of zinc ion transport(GO:0071579)
0.0 0.1 GO:0099547 regulation of translation at synapse, modulating synaptic transmission(GO:0099547) regulation of translation at postsynapse, modulating synaptic transmission(GO:0099578) positive regulation of intracellular transport of viral material(GO:1901254)
0.0 0.2 GO:0010701 positive regulation of norepinephrine secretion(GO:0010701)
0.0 0.1 GO:0014878 response to electrical stimulus involved in regulation of muscle adaptation(GO:0014878)
0.0 0.5 GO:0030238 male sex determination(GO:0030238)
0.0 0.1 GO:0090367 negative regulation of mRNA modification(GO:0090367)
0.0 0.1 GO:1990166 protein localization to site of double-strand break(GO:1990166)
0.0 0.3 GO:0006013 mannose metabolic process(GO:0006013)
0.0 0.0 GO:0010482 epidermal cell division(GO:0010481) regulation of epidermal cell division(GO:0010482)
0.0 2.0 GO:2000649 regulation of sodium ion transmembrane transporter activity(GO:2000649)
0.0 0.1 GO:2000211 regulation of glutamate metabolic process(GO:2000211)
0.0 0.7 GO:0045116 protein neddylation(GO:0045116)
0.0 0.4 GO:2001054 negative regulation of mesenchymal cell apoptotic process(GO:2001054)
0.0 0.7 GO:0031424 keratinization(GO:0031424)
0.0 0.1 GO:0071477 hypotonic salinity response(GO:0042539) cellular hypotonic salinity response(GO:0071477)
0.0 0.5 GO:0008090 retrograde axonal transport(GO:0008090)
0.0 1.0 GO:0090162 establishment of epithelial cell polarity(GO:0090162)
0.0 0.8 GO:0046827 positive regulation of protein export from nucleus(GO:0046827)
0.0 0.3 GO:0021902 commitment of neuronal cell to specific neuron type in forebrain(GO:0021902)
0.0 0.1 GO:0002729 positive regulation of natural killer cell cytokine production(GO:0002729) positive regulation of Fc receptor mediated stimulatory signaling pathway(GO:0060369)
0.0 0.3 GO:0051415 interphase microtubule nucleation by interphase microtubule organizing center(GO:0051415) microtubule nucleation by microtubule organizing center(GO:0051418)
0.0 0.2 GO:0030263 apoptotic chromosome condensation(GO:0030263)
0.0 0.3 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.1 GO:0050651 dermatan sulfate proteoglycan biosynthetic process(GO:0050651)
0.0 0.5 GO:0002507 tolerance induction(GO:0002507)
0.0 0.2 GO:0035385 Roundabout signaling pathway(GO:0035385)
0.0 0.1 GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447)
0.0 0.3 GO:1904262 negative regulation of TORC1 signaling(GO:1904262)
0.0 3.1 GO:0043149 contractile actin filament bundle assembly(GO:0030038) stress fiber assembly(GO:0043149)
0.0 0.2 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.0 0.8 GO:0010107 potassium ion import(GO:0010107)
0.0 0.1 GO:0060397 JAK-STAT cascade involved in growth hormone signaling pathway(GO:0060397)
0.0 0.3 GO:0006895 Golgi to endosome transport(GO:0006895)
0.0 0.1 GO:0030538 embryonic genitalia morphogenesis(GO:0030538)
0.0 0.4 GO:0060088 auditory receptor cell stereocilium organization(GO:0060088)
0.0 0.5 GO:0072673 lamellipodium morphogenesis(GO:0072673)
0.0 0.1 GO:0046726 positive regulation by virus of viral protein levels in host cell(GO:0046726)
0.0 0.2 GO:0002002 regulation of angiotensin levels in blood(GO:0002002)
0.0 0.1 GO:2000016 negative regulation of determination of dorsal identity(GO:2000016)
0.0 0.2 GO:0043313 regulation of neutrophil degranulation(GO:0043313) regulation of neutrophil activation(GO:1902563)
0.0 0.1 GO:0002291 T cell activation via T cell receptor contact with antigen bound to MHC molecule on antigen presenting cell(GO:0002291)
0.0 0.1 GO:0099590 neurotransmitter receptor internalization(GO:0099590)
0.0 0.3 GO:0051457 maintenance of protein location in nucleus(GO:0051457)
0.0 0.7 GO:0010996 response to auditory stimulus(GO:0010996)
0.0 0.1 GO:1901164 negative regulation of trophoblast cell migration(GO:1901164)
0.0 0.2 GO:0048672 positive regulation of collateral sprouting(GO:0048672)
0.0 0.3 GO:0060081 membrane hyperpolarization(GO:0060081)
0.0 0.1 GO:0043031 negative regulation of macrophage activation(GO:0043031)
0.0 0.1 GO:0071044 histone mRNA catabolic process(GO:0071044)
0.0 0.1 GO:1902488 regulation of oligodendrocyte apoptotic process(GO:1900141) negative regulation of oligodendrocyte apoptotic process(GO:1900142) cholangiocyte apoptotic process(GO:1902488) regulation of trophectodermal cell proliferation(GO:1904073) positive regulation of trophectodermal cell proliferation(GO:1904075) regulation of cholangiocyte apoptotic process(GO:1904192) negative regulation of cholangiocyte apoptotic process(GO:1904193)
0.0 0.0 GO:2000097 regulation of smooth muscle cell-matrix adhesion(GO:2000097)
0.0 0.1 GO:0031296 B cell costimulation(GO:0031296)
0.0 1.1 GO:0042475 odontogenesis of dentin-containing tooth(GO:0042475)
0.0 0.6 GO:0042059 negative regulation of epidermal growth factor receptor signaling pathway(GO:0042059)
0.0 0.2 GO:0071378 growth hormone receptor signaling pathway(GO:0060396) cellular response to growth hormone stimulus(GO:0071378)
0.0 0.2 GO:0035745 T-helper 2 cell cytokine production(GO:0035745)
0.0 0.1 GO:0001928 regulation of exocyst assembly(GO:0001928)
0.0 0.2 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.1 GO:0016081 synaptic vesicle docking(GO:0016081)
0.0 0.5 GO:0022617 extracellular matrix disassembly(GO:0022617)
0.0 0.2 GO:0045792 negative regulation of cell size(GO:0045792)
0.0 0.3 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 0.0 GO:0090076 relaxation of skeletal muscle(GO:0090076)
0.0 0.1 GO:0007549 dosage compensation(GO:0007549) dosage compensation by inactivation of X chromosome(GO:0009048)
0.0 0.5 GO:0006891 intra-Golgi vesicle-mediated transport(GO:0006891)
0.0 0.7 GO:0060612 adipose tissue development(GO:0060612)
0.0 0.0 GO:0097051 establishment of protein localization to endoplasmic reticulum membrane(GO:0097051)
0.0 0.0 GO:0060729 intestinal epithelial structure maintenance(GO:0060729)
0.0 0.2 GO:0097500 receptor localization to nonmotile primary cilium(GO:0097500)
0.0 0.5 GO:2000401 regulation of lymphocyte migration(GO:2000401)
0.0 0.1 GO:1900028 negative regulation of ruffle assembly(GO:1900028)
0.0 0.2 GO:0042730 fibrinolysis(GO:0042730)
0.0 0.1 GO:0060005 vestibular reflex(GO:0060005)
0.0 0.1 GO:0016554 cytidine to uridine editing(GO:0016554)
0.0 0.4 GO:0035411 catenin import into nucleus(GO:0035411)
0.0 0.1 GO:0035585 calcium-mediated signaling using extracellular calcium source(GO:0035585) positive regulation of platelet aggregation(GO:1901731)
0.0 0.0 GO:0086053 AV node cell to bundle of His cell communication by electrical coupling(GO:0086053)
0.0 0.1 GO:0051409 response to nitrosative stress(GO:0051409)
0.0 0.1 GO:0021979 hypothalamus cell differentiation(GO:0021979)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.9 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.1 0.4 GO:0034665 integrin alpha1-beta1 complex(GO:0034665)
0.1 0.8 GO:0097443 sorting endosome(GO:0097443)
0.1 1.2 GO:0008024 cyclin/CDK positive transcription elongation factor complex(GO:0008024)
0.1 0.6 GO:0031673 H zone(GO:0031673)
0.1 0.3 GO:0008275 gamma-tubulin small complex(GO:0008275)
0.1 0.2 GO:0031088 platelet dense granule membrane(GO:0031088)
0.1 0.8 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.6 GO:0001739 sex chromatin(GO:0001739)
0.0 0.2 GO:0098890 extrinsic component of postsynaptic membrane(GO:0098890)
0.0 1.4 GO:0033017 sarcoplasmic reticulum membrane(GO:0033017)
0.0 0.6 GO:0060091 kinocilium(GO:0060091)
0.0 1.1 GO:0030056 hemidesmosome(GO:0030056)
0.0 0.2 GO:0060171 stereocilium membrane(GO:0060171)
0.0 0.3 GO:0070847 core mediator complex(GO:0070847)
0.0 0.2 GO:0008537 proteasome activator complex(GO:0008537)
0.0 0.7 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 0.4 GO:0001940 male pronucleus(GO:0001940)
0.0 0.6 GO:0030127 COPII vesicle coat(GO:0030127)
0.0 0.5 GO:0017119 Golgi transport complex(GO:0017119)
0.0 0.5 GO:0031209 SCAR complex(GO:0031209)
0.0 0.1 GO:1990415 Pex17p-Pex14p docking complex(GO:1990415) peroxisomal importomer complex(GO:1990429)
0.0 0.3 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 0.7 GO:0038201 TOR complex(GO:0038201)
0.0 0.1 GO:0030905 retromer, tubulation complex(GO:0030905)
0.0 0.3 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.5 GO:0032045 guanyl-nucleotide exchange factor complex(GO:0032045)
0.0 0.1 GO:1904602 serotonin-activated cation-selective channel complex(GO:1904602)
0.0 0.1 GO:0098843 postsynaptic endocytic zone(GO:0098843)
0.0 0.2 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.0 0.1 GO:0034687 integrin alphaL-beta2 complex(GO:0034687)
0.0 0.7 GO:0001533 cornified envelope(GO:0001533)
0.0 0.1 GO:0017109 glutamate-cysteine ligase complex(GO:0017109)
0.0 3.6 GO:0005913 cell-cell adherens junction(GO:0005913)
0.0 0.1 GO:0098536 deuterosome(GO:0098536)
0.0 0.1 GO:0019034 viral replication complex(GO:0019034) dendritic filopodium(GO:1902737)
0.0 0.2 GO:0005828 kinetochore microtubule(GO:0005828)
0.0 0.5 GO:0090665 dystrophin-associated glycoprotein complex(GO:0016010) glycoprotein complex(GO:0090665)
0.0 0.1 GO:0008282 ATP-sensitive potassium channel complex(GO:0008282)
0.0 0.1 GO:0042585 germinal vesicle(GO:0042585)
0.0 0.2 GO:0061689 tricellular tight junction(GO:0061689)
0.0 0.2 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.2 GO:0061574 ASAP complex(GO:0061574)
0.0 0.3 GO:0030914 STAGA complex(GO:0030914)
0.0 0.8 GO:0032281 AMPA glutamate receptor complex(GO:0032281)
0.0 0.4 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0 0.1 GO:1990726 Lsm1-7-Pat1 complex(GO:1990726)
0.0 0.1 GO:0070761 pre-snoRNP complex(GO:0070761)
0.0 0.1 GO:0012507 ER to Golgi transport vesicle membrane(GO:0012507)
0.0 0.1 GO:1990130 Iml1 complex(GO:1990130)
0.0 0.2 GO:0034464 BBSome(GO:0034464)
0.0 0.3 GO:0016327 apicolateral plasma membrane(GO:0016327)
0.0 0.1 GO:0031465 Cul4B-RING E3 ubiquitin ligase complex(GO:0031465)
0.0 0.8 GO:0005891 voltage-gated calcium channel complex(GO:0005891)
0.0 0.1 GO:0016600 flotillin complex(GO:0016600)
0.0 0.1 GO:0097208 alveolar lamellar body(GO:0097208)
0.0 0.1 GO:0034448 EGO complex(GO:0034448)
0.0 0.1 GO:0000322 storage vacuole(GO:0000322)
0.0 0.2 GO:0034362 low-density lipoprotein particle(GO:0034362)
0.0 0.0 GO:0005607 laminin-2 complex(GO:0005607)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.2 GO:0004823 leucine-tRNA ligase activity(GO:0004823)
0.3 1.9 GO:0001875 lipopolysaccharide receptor activity(GO:0001875)
0.3 1.4 GO:0005220 inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity(GO:0005220)
0.2 1.2 GO:0034211 GTP-dependent protein kinase activity(GO:0034211)
0.2 0.7 GO:0008109 N-acetyllactosaminide beta-1,6-N-acetylglucosaminyltransferase activity(GO:0008109)
0.1 0.4 GO:0050479 glyceryl-ether monooxygenase activity(GO:0050479)
0.1 0.5 GO:0045131 pre-mRNA branch point binding(GO:0045131)
0.1 0.4 GO:0035717 chemokine (C-C motif) ligand 7 binding(GO:0035717)
0.1 1.3 GO:0045236 CXCR chemokine receptor binding(GO:0045236)
0.1 0.3 GO:0051916 granulocyte colony-stimulating factor binding(GO:0051916)
0.1 0.4 GO:0035800 deubiquitinase activator activity(GO:0035800)
0.1 0.3 GO:0035276 ethanol binding(GO:0035276)
0.1 0.6 GO:0005534 galactose binding(GO:0005534)
0.1 0.4 GO:0032896 palmitoyl-CoA 9-desaturase activity(GO:0032896)
0.1 0.3 GO:1904288 BAT3 complex binding(GO:1904288)
0.1 0.4 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.1 0.8 GO:0046790 virion binding(GO:0046790)
0.1 0.6 GO:0003810 protein-glutamine gamma-glutamyltransferase activity(GO:0003810)
0.1 0.2 GO:0005333 norepinephrine transmembrane transporter activity(GO:0005333)
0.1 0.2 GO:0008853 exodeoxyribonuclease III activity(GO:0008853)
0.0 0.2 GO:0051435 BH4 domain binding(GO:0051435)
0.0 0.4 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.3 GO:0035529 NADH pyrophosphatase activity(GO:0035529)
0.0 0.3 GO:0010859 calcium-dependent cysteine-type endopeptidase inhibitor activity(GO:0010859)
0.0 0.1 GO:0008281 sulfonylurea receptor activity(GO:0008281)
0.0 0.8 GO:0005078 MAP-kinase scaffold activity(GO:0005078)
0.0 0.2 GO:0045159 myosin II binding(GO:0045159)
0.0 0.7 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 0.3 GO:0051022 Rho GDP-dissociation inhibitor binding(GO:0051022)
0.0 0.4 GO:0050291 sphingosine N-acyltransferase activity(GO:0050291)
0.0 0.8 GO:0070513 death domain binding(GO:0070513)
0.0 1.8 GO:0061631 ubiquitin conjugating enzyme activity(GO:0061631)
0.0 0.1 GO:0002055 adenine binding(GO:0002055) adenine phosphoribosyltransferase activity(GO:0003999)
0.0 0.2 GO:0019960 C-X3-C chemokine binding(GO:0019960)
0.0 0.2 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.0 0.5 GO:0005176 ErbB-2 class receptor binding(GO:0005176)
0.0 0.3 GO:0016312 inositol bisphosphate phosphatase activity(GO:0016312)
0.0 0.4 GO:0070679 inositol 1,4,5 trisphosphate binding(GO:0070679)
0.0 0.2 GO:0019961 interferon binding(GO:0019961)
0.0 0.4 GO:0042301 phosphate ion binding(GO:0042301)
0.0 0.4 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.0 6.9 GO:0017124 SH3 domain binding(GO:0017124)
0.0 0.5 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.2 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.7 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.5 GO:0004559 alpha-mannosidase activity(GO:0004559)
0.0 2.0 GO:0017080 sodium channel regulator activity(GO:0017080)
0.0 0.8 GO:0005031 tumor necrosis factor-activated receptor activity(GO:0005031) death receptor activity(GO:0005035)
0.0 0.6 GO:0004622 lysophospholipase activity(GO:0004622)
0.0 0.1 GO:0030369 ICAM-3 receptor activity(GO:0030369)
0.0 0.2 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 0.0 GO:0070506 high-density lipoprotein particle receptor activity(GO:0070506)
0.0 0.1 GO:0004357 glutamate-cysteine ligase activity(GO:0004357)
0.0 0.2 GO:0032051 clathrin light chain binding(GO:0032051)
0.0 0.2 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.9 GO:0030506 ankyrin binding(GO:0030506)
0.0 0.1 GO:0001888 glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity(GO:0001888)
0.0 0.1 GO:1990460 leptin receptor binding(GO:1990460)
0.0 0.7 GO:0005242 inward rectifier potassium channel activity(GO:0005242)
0.0 0.3 GO:0008484 sulfuric ester hydrolase activity(GO:0008484)
0.0 0.1 GO:0001849 complement component C1q binding(GO:0001849)
0.0 0.8 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.1 GO:0004974 leukotriene receptor activity(GO:0004974)
0.0 0.1 GO:0015018 galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase activity(GO:0015018)
0.0 0.1 GO:0008240 tripeptidyl-peptidase activity(GO:0008240)
0.0 0.1 GO:0035827 rubidium ion transmembrane transporter activity(GO:0035827)
0.0 0.1 GO:0004630 phospholipase D activity(GO:0004630) N-acylphosphatidylethanolamine-specific phospholipase D activity(GO:0070290)
0.0 0.1 GO:0022850 serotonin-gated cation channel activity(GO:0022850)
0.0 0.5 GO:0031435 mitogen-activated protein kinase kinase kinase binding(GO:0031435)
0.0 0.4 GO:0043422 protein kinase B binding(GO:0043422)
0.0 0.1 GO:0005094 Rho GDP-dissociation inhibitor activity(GO:0005094)
0.0 0.7 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.1 GO:0003910 DNA ligase activity(GO:0003909) DNA ligase (ATP) activity(GO:0003910)
0.0 0.2 GO:0038036 sphingosine-1-phosphate receptor activity(GO:0038036)
0.0 0.1 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.0 0.7 GO:1990841 promoter-specific chromatin binding(GO:1990841)
0.0 0.2 GO:0001087 transcription factor activity, sequence-specific DNA binding, RNA polymerase recruiting(GO:0001011) transcription factor activity, TFIIB-class binding(GO:0001087)
0.0 0.1 GO:0008093 cytoskeletal adaptor activity(GO:0008093)
0.0 0.3 GO:0042813 Wnt-activated receptor activity(GO:0042813)
0.0 0.1 GO:0038085 vascular endothelial growth factor binding(GO:0038085)
0.0 0.7 GO:0017112 Rab guanyl-nucleotide exchange factor activity(GO:0017112)
0.0 0.6 GO:0005484 SNAP receptor activity(GO:0005484)
0.0 0.3 GO:0008179 adenylate cyclase binding(GO:0008179)
0.0 0.8 GO:0001540 beta-amyloid binding(GO:0001540)
0.0 0.2 GO:0000339 RNA cap binding(GO:0000339)
0.0 0.6 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.6 GO:0004683 calmodulin-dependent protein kinase activity(GO:0004683)
0.0 0.3 GO:0008009 chemokine activity(GO:0008009)
0.0 0.0 GO:1903763 gap junction channel activity involved in cardiac conduction electrical coupling(GO:0086075) gap junction channel activity involved in AV node cell-bundle of His cell electrical coupling(GO:0086077) gap junction channel activity involved in cell communication by electrical coupling(GO:1903763)
0.0 0.1 GO:0010997 anaphase-promoting complex binding(GO:0010997)
0.0 1.4 GO:0004540 ribonuclease activity(GO:0004540)
0.0 0.1 GO:0001161 intronic transcription regulatory region sequence-specific DNA binding(GO:0001161)
0.0 0.2 GO:0051011 microtubule minus-end binding(GO:0051011)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 3.2 PID ECADHERIN KERATINOCYTE PATHWAY E-cadherin signaling in keratinocytes
0.1 4.7 PID ERBB1 INTERNALIZATION PATHWAY Internalization of ErbB1
0.0 1.8 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 0.1 PID VEGFR1 PATHWAY VEGFR1 specific signals
0.0 1.5 PID TOLL ENDOGENOUS PATHWAY Endogenous TLR signaling
0.0 0.7 PID ERB GENOMIC PATHWAY Validated nuclear estrogen receptor beta network
0.0 0.9 PID ARF 3PATHWAY Arf1 pathway
0.0 0.5 ST PHOSPHOINOSITIDE 3 KINASE PATHWAY PI3K Pathway
0.0 0.4 PID EPHA2 FWD PATHWAY EPHA2 forward signaling
0.0 0.3 PID EPO PATHWAY EPO signaling pathway
0.0 0.3 ST JAK STAT PATHWAY Jak-STAT Pathway
0.0 1.2 PID CDC42 REG PATHWAY Regulation of CDC42 activity
0.0 1.2 PID AJDISS 2PATHWAY Posttranslational regulation of adherens junction stability and dissassembly
0.0 0.6 PID ECADHERIN NASCENT AJ PATHWAY E-cadherin signaling in the nascent adherens junction
0.0 0.2 PID EPHRINB REV PATHWAY Ephrin B reverse signaling
0.0 0.9 PID WNT NONCANONICAL PATHWAY Noncanonical Wnt signaling pathway
0.0 0.3 PID S1P S1P4 PATHWAY S1P4 pathway
0.0 0.2 PID IL8 CXCR1 PATHWAY IL8- and CXCR1-mediated signaling events
0.0 1.0 SIG INSULIN RECEPTOR PATHWAY IN CARDIAC MYOCYTES Genes related to the insulin receptor pathway
0.0 0.7 PID ALK1 PATHWAY ALK1 signaling events
0.0 0.5 PID CD40 PATHWAY CD40/CD40L signaling
0.0 0.2 PID IL8 CXCR2 PATHWAY IL8- and CXCR2-mediated signaling events
0.0 0.7 PID THROMBIN PAR1 PATHWAY PAR1-mediated thrombin signaling events
0.0 0.9 PID P38 ALPHA BETA DOWNSTREAM PATHWAY Signaling mediated by p38-alpha and p38-beta
0.0 0.2 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.4 PID PRL SIGNALING EVENTS PATHWAY Signaling events mediated by PRL
0.0 0.4 PID INTEGRIN A9B1 PATHWAY Alpha9 beta1 integrin signaling events
0.0 0.4 PID TNF PATHWAY TNF receptor signaling pathway
0.0 0.6 PID FGF PATHWAY FGF signaling pathway
0.0 1.0 PID CERAMIDE PATHWAY Ceramide signaling pathway
0.0 0.3 PID INTEGRIN2 PATHWAY Beta2 integrin cell surface interactions
0.0 0.5 PID BCR 5PATHWAY BCR signaling pathway
0.0 0.2 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.4 PID IL6 7 PATHWAY IL6-mediated signaling events
0.0 0.1 PID IL2 1PATHWAY IL2-mediated signaling events
0.0 0.4 NABA PROTEOGLYCANS Genes encoding proteoglycans

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.9 REACTOME IKK COMPLEX RECRUITMENT MEDIATED BY RIP1 Genes involved in IKK complex recruitment mediated by RIP1
0.1 1.2 REACTOME ELEVATION OF CYTOSOLIC CA2 LEVELS Genes involved in Elevation of cytosolic Ca2+ levels
0.1 1.7 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.1 1.8 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.1 0.8 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.1 0.9 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.1 2.9 REACTOME CHEMOKINE RECEPTORS BIND CHEMOKINES Genes involved in Chemokine receptors bind chemokines
0.0 1.3 REACTOME EGFR DOWNREGULATION Genes involved in EGFR downregulation
0.0 1.1 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.0 0.5 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC
0.0 0.2 REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS Genes involved in The role of Nef in HIV-1 replication and disease pathogenesis
0.0 0.5 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.5 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.3 REACTOME G ALPHA Z SIGNALLING EVENTS Genes involved in G alpha (z) signalling events
0.0 1.0 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 1.0 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.7 REACTOME ANTIGEN ACTIVATES B CELL RECEPTOR LEADING TO GENERATION OF SECOND MESSENGERS Genes involved in Antigen Activates B Cell Receptor Leading to Generation of Second Messengers
0.0 0.5 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.0 0.5 REACTOME KINESINS Genes involved in Kinesins
0.0 0.3 REACTOME IL 7 SIGNALING Genes involved in Interleukin-7 signaling
0.0 0.3 REACTOME RECRUITMENT OF NUMA TO MITOTIC CENTROSOMES Genes involved in Recruitment of NuMA to mitotic centrosomes
0.0 0.5 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.4 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.0 0.3 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 0.1 REACTOME PLATELET ADHESION TO EXPOSED COLLAGEN Genes involved in Platelet Adhesion to exposed collagen
0.0 0.2 REACTOME APC C CDC20 MEDIATED DEGRADATION OF CYCLIN B Genes involved in APC/C:Cdc20 mediated degradation of Cyclin B
0.0 0.2 REACTOME DCC MEDIATED ATTRACTIVE SIGNALING Genes involved in DCC mediated attractive signaling
0.0 0.4 REACTOME SIGNALING BY ROBO RECEPTOR Genes involved in Signaling by Robo receptor
0.0 0.1 REACTOME REGULATION OF KIT SIGNALING Genes involved in Regulation of KIT signaling