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avrg: GFI1 WT vs 36n/n vs KD

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Results for Esr1

Z-value: 0.67

Motif logo

Transcription factors associated with Esr1

Gene Symbol Gene ID Gene Info
ENSMUSG00000019768.17 estrogen receptor 1 (alpha)

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Esr1mm39_v1_chr10_+_4561974_45620750.976.4e-03Click!

Activity profile of Esr1 motif

Sorted Z-values of Esr1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr9_+_110848339 0.73 ENSMUST00000198884.5
ENSMUST00000196777.5
ENSMUST00000196209.5
ENSMUST00000035077.8
ENSMUST00000196122.3
lactotransferrin
chr11_-_102255999 0.34 ENSMUST00000006749.10
solute carrier family 4 (anion exchanger), member 1
chr16_+_22926162 0.28 ENSMUST00000023599.13
ENSMUST00000168891.8
eukaryotic translation initiation factor 4A2
chr7_+_125202653 0.26 ENSMUST00000206103.2
ENSMUST00000033000.8
interleukin 21 receptor
chr7_-_144493560 0.25 ENSMUST00000093962.5
cyclin D1
chr2_-_50186690 0.23 ENSMUST00000144143.8
ENSMUST00000102769.11
ENSMUST00000133768.2
methylmalonic aciduria (cobalamin deficiency) cblD type, with homocystinuria
chr11_+_87684299 0.22 ENSMUST00000020779.11
myeloperoxidase
chr17_+_28075415 0.20 ENSMUST00000114849.3
UHRF1 (ICBP90) binding protein 1
chr11_+_87684548 0.19 ENSMUST00000143021.9
myeloperoxidase
chr19_+_3372296 0.19 ENSMUST00000237938.2
carnitine palmitoyltransferase 1a, liver
chr11_+_23615612 0.18 ENSMUST00000109525.8
ENSMUST00000020520.11
pseudouridylate synthase 10
chr6_-_69415741 0.18 ENSMUST00000103354.3
immunoglobulin kappa variable 4-59
chr6_-_69584812 0.18 ENSMUST00000103359.3
immunoglobulin kappa variable 4-55
chr5_+_3621673 0.17 ENSMUST00000008451.12
RIKEN cDNA 1700109H08 gene
chr5_-_113428407 0.17 ENSMUST00000112324.2
ENSMUST00000057209.12
small G protein signaling modulator 1
chr8_+_72021567 0.16 ENSMUST00000034267.5
solute carrier family 27 (fatty acid transporter), member 1
chr1_-_63215812 0.16 ENSMUST00000185847.2
ENSMUST00000185732.7
ENSMUST00000188370.7
ENSMUST00000168099.9
NADH:ubiquinone oxidoreductase core subunit S1
chr5_+_122347912 0.15 ENSMUST00000143560.8
hydrogen voltage-gated channel 1
chr7_-_140462187 0.15 ENSMUST00000211179.2
sirtuin 3
chr8_+_72021510 0.15 ENSMUST00000212889.2
solute carrier family 27 (fatty acid transporter), member 1
chr11_+_87685032 0.15 ENSMUST00000121303.8
myeloperoxidase
chr7_+_46496929 0.15 ENSMUST00000132157.2
ENSMUST00000210631.2
lactate dehydrogenase A
chr14_-_56322654 0.14 ENSMUST00000015594.9
mast cell protease 8
chr7_+_46496552 0.14 ENSMUST00000005051.6
lactate dehydrogenase A
chr11_-_31621863 0.14 ENSMUST00000058060.14
biorientation of chromosomes in cell division 1
chr10_+_79722081 0.13 ENSMUST00000046091.7
elastase, neutrophil expressed
chr19_-_4240984 0.13 ENSMUST00000045864.4
TBC1 domain family, member 10c
chr7_-_125976580 0.13 ENSMUST00000119846.8
ENSMUST00000119754.8
ENSMUST00000032994.15
spinster homolog 1
chr9_+_107926502 0.13 ENSMUST00000047947.9
GDP-mannose pyrophosphorylase B
chr11_-_117764258 0.13 ENSMUST00000033230.8
threonine aldolase 1
chr7_+_144468837 0.13 ENSMUST00000128057.8
ENSMUST00000033388.12
ENSMUST00000141737.2
ENSMUST00000105895.2
ABCE maturation factor
chr11_-_99045894 0.13 ENSMUST00000103134.4
chemokine (C-C motif) receptor 7
chr17_+_28491085 0.13 ENSMUST00000169040.3
peroxisome proliferator activator receptor delta
chr3_+_96088467 0.13 ENSMUST00000035371.9
synaptic vesicle glycoprotein 2 a
chr8_+_121395047 0.13 ENSMUST00000181795.2
cytochrome c oxidase subunit 4I1
chr5_+_36050663 0.12 ENSMUST00000064571.11
actin filament associated protein 1
chr17_+_35539505 0.12 ENSMUST00000105041.10
ENSMUST00000073208.6
histocompatibility 2, Q region locus 1
chr13_-_107073415 0.12 ENSMUST00000080856.14
importin 11
chr15_+_79784543 0.12 ENSMUST00000230741.2
apolipoprotein B mRNA editing enzyme, catalytic polypeptide 3
chr4_+_99812912 0.12 ENSMUST00000102783.5
phosphoglucomutase 1
chr4_+_140427799 0.12 ENSMUST00000071169.9
regulator of chromosome condensation 2
chr10_+_39245746 0.12 ENSMUST00000063091.13
ENSMUST00000099967.10
ENSMUST00000126486.8
Fyn proto-oncogene
chr10_+_80692948 0.12 ENSMUST00000220091.2
signal peptide peptidase like 2B
chr19_-_43512929 0.12 ENSMUST00000026196.14
glutamic-oxaloacetic transaminase 1, soluble
chr15_+_79784365 0.12 ENSMUST00000230135.2
apolipoprotein B mRNA editing enzyme, catalytic polypeptide 3
chr7_-_140462221 0.12 ENSMUST00000026559.14
sirtuin 3
chr1_-_63215952 0.12 ENSMUST00000185412.7
ENSMUST00000027111.15
ENSMUST00000189664.2
NADH:ubiquinone oxidoreductase core subunit S1
chr17_+_37581103 0.12 ENSMUST00000038580.7
histocompatibility 2, M region locus 3
chr17_-_26063488 0.11 ENSMUST00000176709.2
ras homolog family member T2
chr14_-_30909082 0.11 ENSMUST00000170253.8
nischarin
chr8_+_73488496 0.11 ENSMUST00000058099.9
coagulation factor II (thrombin) receptor-like 3
chr15_+_76227695 0.11 ENSMUST00000023210.8
ENSMUST00000231045.2
cytochrome c-1
chr18_-_34757653 0.11 ENSMUST00000003876.10
ENSMUST00000115766.8
ENSMUST00000097626.10
ENSMUST00000115765.2
bromodomain containing 8
chr7_+_141055350 0.11 ENSMUST00000138092.8
ENSMUST00000146305.8
tetraspanin 4
chr7_+_46496506 0.11 ENSMUST00000209984.2
lactate dehydrogenase A
chr2_+_30331839 0.11 ENSMUST00000131476.8
protein phosphatase 2 protein activator
chr4_+_107659361 0.11 ENSMUST00000106731.4
low density lipoprotein receptor-related protein 8, apolipoprotein e receptor
chr7_+_140462343 0.11 ENSMUST00000163610.9
ENSMUST00000164681.8
proteasome (prosome, macropain) 26S subunit, non-ATPase, 13
chr2_+_181506130 0.11 ENSMUST00000039551.9
polymerase (RNA) III (DNA directed) polypeptide K
chr4_+_150321142 0.11 ENSMUST00000150175.8
enolase 1, alpha non-neuron
chr3_+_90011435 0.11 ENSMUST00000029548.9
ENSMUST00000200410.2
nucleoporin 210-like
chr10_-_127147609 0.11 ENSMUST00000037290.12
ENSMUST00000171564.8
methionine-tRNA synthetase 1
chr11_-_116164928 0.11 ENSMUST00000106425.4
signal recognition particle 68
chr3_-_19319155 0.10 ENSMUST00000091314.11
phosphodiesterase 7A
chr9_+_37119472 0.10 ENSMUST00000034632.10
transmembrane protein 218
chr4_-_150993886 0.10 ENSMUST00000128075.8
Parkinson disease (autosomal recessive, early onset) 7
chr11_+_69737200 0.10 ENSMUST00000108632.8
phospholipid scramblase 3
chr3_-_59118293 0.10 ENSMUST00000040622.3
purinergic receptor P2Y, G-protein coupled 13
chr5_+_137517140 0.10 ENSMUST00000031727.10
GRB10 interacting GYF protein 1
chr16_+_16120810 0.10 ENSMUST00000159962.8
ENSMUST00000059955.15
tyrosyl-tRNA synthetase 2 (mitochondrial)
chr10_-_81201642 0.10 ENSMUST00000020456.5
RIKEN cDNA 4930404N11 gene
chr11_-_59397352 0.10 ENSMUST00000013262.15
ENSMUST00000101150.9
zinc finger with KRAB and SCAN domains 17
chr16_-_20245138 0.10 ENSMUST00000079158.13
ATP-binding cassette, sub-family C (CFTR/MRP), member 5
chr18_-_38130581 0.10 ENSMUST00000042944.9
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
chrX_+_73468140 0.10 ENSMUST00000135165.8
ENSMUST00000114128.8
ENSMUST00000004330.10
ENSMUST00000114133.9
ENSMUST00000114129.9
ENSMUST00000132749.2
inhibitor of kappaB kinase gamma
chr19_+_4806544 0.10 ENSMUST00000182821.8
ENSMUST00000036744.8
RNA binding motif protein 4B
chr9_-_55419442 0.10 ENSMUST00000034866.9
electron transferring flavoprotein, alpha polypeptide
chr3_-_95125190 0.10 ENSMUST00000136139.8
GA repeat binding protein, beta 2
chr15_-_77527470 0.10 ENSMUST00000181154.2
ENSMUST00000180949.8
ENSMUST00000166623.10
apolipoprotein L 11b
chr4_-_59783780 0.10 ENSMUST00000107526.8
ENSMUST00000095063.11
INTS3 and NABP interacting protein
chr2_-_101451383 0.09 ENSMUST00000090513.11
intraflagellar transport associated protein
chr14_+_66534478 0.09 ENSMUST00000022623.13
tripartite motif-containing 35
chr9_-_64160899 0.09 ENSMUST00000005066.9
mitogen-activated protein kinase kinase 1
chr7_+_28416270 0.09 ENSMUST00000108279.9
F-box protein 17
chr2_-_26270612 0.09 ENSMUST00000114115.9
ENSMUST00000035427.11
small nuclear RNA activating complex, polypeptide 4
chr7_+_28416194 0.09 ENSMUST00000032818.13
F-box protein 17
chr1_-_160898181 0.09 ENSMUST00000035430.4
aspartyl-tRNA synthetase 2 (mitochondrial)
chr4_-_132072988 0.09 ENSMUST00000030726.13
regulator of chromosome condensation 1
chr19_-_5776268 0.09 ENSMUST00000075606.6
ENSMUST00000236215.2
ENSMUST00000235730.2
ENSMUST00000237081.2
ENSMUST00000049295.15
EH domain binding protein 1-like 1
chr8_-_106660470 0.09 ENSMUST00000034368.8
chymotrypsin-like
chr9_+_44308149 0.09 ENSMUST00000215420.2
solute carrier family 37 (glucose-6-phosphate transporter), member 4
chr1_+_91468409 0.09 ENSMUST00000027538.9
ENSMUST00000190484.7
ENSMUST00000186068.2
ankyrin repeat and SOCS box-containing 1
chr12_+_55431007 0.09 ENSMUST00000163070.8
proteasome subunit alpha 6
chr7_-_143376529 0.09 ENSMUST00000156779.2
ENSMUST00000033415.15
NAD synthetase 1
chr15_-_102097387 0.09 ENSMUST00000230288.2
cysteine sulfinic acid decarboxylase
chr12_-_69771604 0.08 ENSMUST00000021370.10
L-2-hydroxyglutarate dehydrogenase
chr8_-_106015682 0.08 ENSMUST00000212922.2
ENSMUST00000212219.2
RIKEN cDNA 4931428F04 gene
chr6_-_70383976 0.08 ENSMUST00000103393.2
immunoglobulin kappa variable 6-15
chr3_+_88744323 0.08 ENSMUST00000081695.14
ENSMUST00000090942.6
gon-4-like (C.elegans)
chr4_+_49521176 0.08 ENSMUST00000042964.13
ENSMUST00000107696.2
zinc finger protein 189
chr9_-_44253630 0.08 ENSMUST00000097558.5
hydroxymethylbilane synthase
chr18_-_12254562 0.08 ENSMUST00000055447.14
ENSMUST00000209859.2
transmembrane protein 241
chr17_-_33007238 0.08 ENSMUST00000159086.10
zinc finger protein 871
chr4_-_132073048 0.08 ENSMUST00000084250.11
regulator of chromosome condensation 1
chr9_+_65583852 0.08 ENSMUST00000136166.3
ornithine decarboxylase antizyme 2
chr10_+_81012465 0.08 ENSMUST00000047864.11
eukaryotic translation elongation factor 2
chr6_+_48653047 0.08 ENSMUST00000054050.5
GTPase, IMAP family member 9
chr1_-_171050004 0.08 ENSMUST00000147246.2
ENSMUST00000111326.8
ENSMUST00000138184.8
translocase of outer mitochondrial membrane 40-like
chr17_-_28128180 0.08 ENSMUST00000114848.8
TATA-box binding protein associated factor 11
chr1_+_127796508 0.08 ENSMUST00000037649.6
ENSMUST00000212506.2
RAB3 GTPase activating protein subunit 1
chr10_+_62897353 0.08 ENSMUST00000178684.3
ENSMUST00000020266.15
phenazine biosynthesis-like protein domain containing 1
chrX_+_73348832 0.08 ENSMUST00000153141.2
guanosine diphosphate (GDP) dissociation inhibitor 1
chr6_+_87890906 0.08 ENSMUST00000032141.14
5-hydroxymethylcytosine (hmC) binding, ES cell specific
chr4_-_86530245 0.08 ENSMUST00000125481.3
ENSMUST00000070607.9
HAUS augmin-like complex, subunit 6
chr6_-_128414616 0.08 ENSMUST00000151796.3
FK506 binding protein 4
chr6_+_116185077 0.08 ENSMUST00000204051.2
WASH complex subunit 2`
chr16_-_91415873 0.08 ENSMUST00000143058.2
ENSMUST00000049244.10
ENSMUST00000169982.2
ENSMUST00000133731.2
DnaJ heat shock protein family (Hsp40) member C28
chr6_-_70194405 0.08 ENSMUST00000103384.2
immunoglobulin kappa chain variable 8-24
chr19_-_4241034 0.08 ENSMUST00000237495.2
TBC1 domain family, member 10c
chr9_+_107926441 0.08 ENSMUST00000112295.9
GDP-mannose pyrophosphorylase B
chr4_+_106591080 0.08 ENSMUST00000047620.3
family with sequence simliarity 151, member A
chr7_+_140461860 0.08 ENSMUST00000026560.14
proteasome (prosome, macropain) 26S subunit, non-ATPase, 13
chr17_-_26160872 0.08 ENSMUST00000139226.2
ENSMUST00000097368.10
ENSMUST00000140304.2
ENSMUST00000026823.16
phosphatidylinositol glycan anchor biosynthesis, class Q
chr9_-_96993169 0.08 ENSMUST00000085206.11
solute carrier family 25, member 36
chrX_-_92675719 0.07 ENSMUST00000006856.3
polymerase (DNA directed), alpha 1
chr2_-_180928867 0.07 ENSMUST00000130475.8
glucocorticoid modulatory element binding protein 2
chr11_-_78427061 0.07 ENSMUST00000017759.9
ENSMUST00000108277.3
tumor necrosis factor, alpha-induced protein 1 (endothelial)
chr3_-_95125002 0.07 ENSMUST00000107209.8
GA repeat binding protein, beta 2
chr6_+_116528102 0.07 ENSMUST00000122096.3
eukaryotic translation initiation factor 4A3 like 2
chrX_-_149879501 0.07 ENSMUST00000112683.9
ENSMUST00000026295.10
TSR2 20S rRNA accumulation
chr15_-_102097466 0.07 ENSMUST00000023805.3
cysteine sulfinic acid decarboxylase
chr2_+_130969200 0.07 ENSMUST00000099349.10
ENSMUST00000100763.9
heat shock protein 12B
chr7_-_98790275 0.07 ENSMUST00000037968.10
UV radiation resistance associated gene
chr16_+_32002750 0.07 ENSMUST00000231512.2
brain expressed family member 6
chr9_+_21095399 0.07 ENSMUST00000115458.9
phosphodiesterase 4A, cAMP specific
chr8_+_124170027 0.07 ENSMUST00000108830.2
differentially expressed in FDCP 8
chr14_+_75253453 0.07 ENSMUST00000036072.8
RUN and cysteine rich domain containing beclin 1 interacting protein like
chr17_-_26138480 0.07 ENSMUST00000164982.8
ENSMUST00000179998.8
ENSMUST00000167626.8
ENSMUST00000164738.2
ENSMUST00000026826.14
ENSMUST00000167018.8
Rab40C, member RAS oncogene family
chr17_-_26063391 0.07 ENSMUST00000176591.8
ras homolog family member T2
chr2_-_164675357 0.07 ENSMUST00000042775.5
neuralized E3 ubiquitin protein ligase 2
chr4_+_116565898 0.07 ENSMUST00000135499.8
coiled-coil domain containing 163
chr12_+_84408803 0.07 ENSMUST00000110278.8
ENSMUST00000145522.2
coenzyme Q6 monooxygenase
chr1_-_93729562 0.07 ENSMUST00000112890.3
deoxythymidylate kinase
chr11_-_70873773 0.07 ENSMUST00000078528.7
complement component 1, q subcomponent binding protein
chr17_+_25517363 0.07 ENSMUST00000037453.4
protease, serine 34
chr8_+_85415935 0.07 ENSMUST00000125370.10
ENSMUST00000175784.2
tRNA methyltransferase 1
chr13_+_49495025 0.07 ENSMUST00000048544.14
ENSMUST00000110084.4
ENSMUST00000110085.11
BICD cargo adaptor 2
chr6_+_3498382 0.07 ENSMUST00000001412.17
ENSMUST00000170873.10
ENSMUST00000164052.5
VPS50 EARP/GARPII complex subunit
chr2_+_162773440 0.07 ENSMUST00000130411.7
ENSMUST00000126163.3
serine and arginine-rich splicing factor 6
chr17_-_23990512 0.07 ENSMUST00000226460.2
FLYWCH-type zinc finger 1
chr19_-_46033353 0.07 ENSMUST00000026252.14
ENSMUST00000156585.9
ENSMUST00000185355.7
ENSMUST00000152946.8
LIM domain binding 1
chr6_-_6217126 0.07 ENSMUST00000188414.4
solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 13
chr19_+_56536685 0.07 ENSMUST00000071423.7
NHL repeat containing 2
chr5_+_134212836 0.07 ENSMUST00000016086.10
GTF2I repeat domain containing 2
chr17_-_28705055 0.07 ENSMUST00000233870.2
FK506 binding protein 5
chr7_-_126074256 0.07 ENSMUST00000205440.2
ENSMUST00000032978.8
ENSMUST00000205340.2
SH2B adaptor protein 1
chr16_+_22926504 0.07 ENSMUST00000187168.7
ENSMUST00000232287.2
ENSMUST00000077605.12
eukaryotic translation initiation factor 4A2
chr2_+_163503415 0.07 ENSMUST00000135537.8
protein kinase inhibitor, gamma
chr5_-_100867520 0.07 ENSMUST00000112908.2
ENSMUST00000045617.15
heparanase
chr13_+_38223023 0.07 ENSMUST00000226110.2
RIO kinase 1
chr9_+_113760002 0.07 ENSMUST00000084885.12
ENSMUST00000009885.14
upstream binding protein 1
chr9_-_42383494 0.07 ENSMUST00000128959.8
ENSMUST00000066148.12
ENSMUST00000138506.8
tubulin folding cofactor E-like
chr7_+_89814713 0.07 ENSMUST00000207084.2
phosphatidylinositol binding clathrin assembly protein
chr11_-_121120052 0.07 ENSMUST00000169393.8
ENSMUST00000106115.8
ENSMUST00000038709.14
ENSMUST00000147490.6
cytochrome b 245 chaperone 1
chr14_+_30547541 0.07 ENSMUST00000006701.8
STIM activating enhancer
chr4_+_21879660 0.07 ENSMUST00000029909.3
coenzyme Q3 methyltransferase
chr5_+_122348140 0.07 ENSMUST00000196187.5
ENSMUST00000100747.3
hydrogen voltage-gated channel 1
chr16_+_35590745 0.07 ENSMUST00000231579.2
Hspb associated protein 1
chr12_-_115766700 0.07 ENSMUST00000196587.5
ENSMUST00000103543.3
immunoglobulin heavy variable V1-74
chr14_-_104760051 0.07 ENSMUST00000022716.4
ENSMUST00000228448.2
ENSMUST00000227640.2
ORC ubiquitin ligase 1
chr14_-_60488922 0.07 ENSMUST00000225311.2
ENSMUST00000041905.8
predicted gene, 49336
chr3_-_79535966 0.06 ENSMUST00000120992.8
electron transferring flavoprotein, dehydrogenase
chrX_+_158771429 0.06 ENSMUST00000033665.9
mitogen-activated protein kinase kinase kinase 15
chr2_+_28531239 0.06 ENSMUST00000028155.12
ENSMUST00000113869.8
ENSMUST00000113867.9
TSC complex subunit 1
chr17_+_35481702 0.06 ENSMUST00000172785.8
histocompatibility 2, D region locus 1
chr8_-_33820578 0.06 ENSMUST00000211498.2
Werner syndrome RecQ like helicase
chr2_-_155668567 0.06 ENSMUST00000109638.2
ENSMUST00000134278.2
eukaryotic translation initiation factor 6
chr19_+_46316617 0.06 ENSMUST00000026256.9
ENSMUST00000177667.2
F-box and leucine-rich repeat protein 15
chrX_+_73352694 0.06 ENSMUST00000130581.2
guanosine diphosphate (GDP) dissociation inhibitor 1
chr9_-_119813724 0.06 ENSMUST00000213936.2
cysteine-serine-rich nuclear protein 1
chr11_+_50101717 0.06 ENSMUST00000147468.8
mannoside acetylglucosaminyltransferase 4, isoenzyme B
chr12_-_113324852 0.06 ENSMUST00000223179.2
ENSMUST00000103423.3
Immunoglobulin heavy constant gamma 3
chr11_+_101339233 0.06 ENSMUST00000010502.13
interferon-induced protein 35
chr2_+_22785534 0.06 ENSMUST00000053729.14
prenyl (solanesyl) diphosphate synthase, subunit 1
chr5_+_138115165 0.06 ENSMUST00000062350.15
ENSMUST00000110961.9
ENSMUST00000080732.10
ENSMUST00000110960.9
ENSMUST00000142185.8
ENSMUST00000136425.2
ENSMUST00000110959.2
zinc finger and SCAN domain containing 21
chr15_+_100251030 0.06 ENSMUST00000075675.7
ENSMUST00000088142.6
ENSMUST00000176287.2
methyltransferase hypoxia inducible domain containing 1
methyltransferase like 7A2
chr7_-_30443106 0.06 ENSMUST00000182634.8
glyceraldehyde-3-phosphate dehydrogenase, spermatogenic
chr11_-_69553390 0.06 ENSMUST00000129224.8
ENSMUST00000155200.8
mannose-P-dolichol utilization defect 1
chr8_+_11608412 0.06 ENSMUST00000209565.2
inhibitor of growth family, member 1
chr15_+_82012114 0.06 ENSMUST00000089174.6
coiled-coil domain containing 134
chr18_-_56705960 0.06 ENSMUST00000174518.8
aldehyde dehydrogenase family 7, member A1
chr2_-_105734829 0.06 ENSMUST00000122965.8
elongator acetyltransferase complex subunit 4
chr8_-_112026854 0.06 ENSMUST00000038739.5
ring finger and WD repeat domain 3
chr10_+_79650496 0.06 ENSMUST00000218857.2
ENSMUST00000220365.2
paralemmin
chr14_-_52252003 0.06 ENSMUST00000226522.2
zinc finger protein 219
chr4_-_115910577 0.06 ENSMUST00000165493.8
NOL1/NOP2/Sun domain family, member 4
chr1_+_131616407 0.06 ENSMUST00000064679.9
ENSMUST00000064664.10
ENSMUST00000136247.8
RAB7B, member RAS oncogene family
chr1_-_75156993 0.06 ENSMUST00000027396.15
ATP-binding cassette, sub-family B (MDR/TAP), member 6
chr6_+_70192384 0.06 ENSMUST00000103383.3
immunoglobulin kappa chain variable 6-25
chr4_-_49521036 0.06 ENSMUST00000057829.4
mitochondrial ribosomal protein L50

Network of associatons between targets according to the STRING database.

First level regulatory network of Esr1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0002149 hypochlorous acid metabolic process(GO:0002148) hypochlorous acid biosynthetic process(GO:0002149)
0.2 0.7 GO:1900191 biofilm formation(GO:0042710) single-species biofilm formation(GO:0044010) single-species biofilm formation in or on host organism(GO:0044407) membrane disruption in other organism(GO:0051673) regulation of single-species biofilm formation(GO:1900190) negative regulation of single-species biofilm formation(GO:1900191) regulation of single-species biofilm formation in or on host organism(GO:1900228) negative regulation of single-species biofilm formation in or on host organism(GO:1900229)
0.1 0.3 GO:0001579 medium-chain fatty acid transport(GO:0001579)
0.0 0.1 GO:0018160 peptidyl-pyrromethane cofactor linkage(GO:0018160)
0.0 0.1 GO:0070947 neutrophil mediated killing of fungus(GO:0070947)
0.0 0.1 GO:0097021 regulation of tolerance induction to self antigen(GO:0002649) lymphocyte migration into lymphoid organs(GO:0097021) positive regulation of thymocyte migration(GO:2000412) regulation of dendritic cell dendrite assembly(GO:2000547)
0.0 0.4 GO:0019661 glucose catabolic process to lactate(GO:0019659) glycolytic fermentation(GO:0019660) glucose catabolic process to lactate via pyruvate(GO:0019661)
0.0 0.2 GO:0042412 taurine biosynthetic process(GO:0042412)
0.0 0.1 GO:0072356 chromosome passenger complex localization to kinetochore(GO:0072356)
0.0 0.1 GO:0006106 fumarate metabolic process(GO:0006106) aspartate catabolic process(GO:0006533)
0.0 0.1 GO:0002476 antigen processing and presentation of endogenous peptide antigen via MHC class Ib(GO:0002476)
0.0 0.1 GO:0030472 mitotic spindle organization in nucleus(GO:0030472)
0.0 0.3 GO:0000320 re-entry into mitotic cell cycle(GO:0000320)
0.0 0.1 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.0 0.1 GO:0034499 late endosome to Golgi transport(GO:0034499)
0.0 0.1 GO:0015783 GDP-fucose transport(GO:0015783) purine nucleotide-sugar transport(GO:0036079)
0.0 0.1 GO:0072531 pyrimidine-containing compound transmembrane transport(GO:0072531)
0.0 0.2 GO:0070127 tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.0 0.1 GO:0033762 response to glucagon(GO:0033762)
0.0 0.1 GO:0097051 establishment of protein localization to endoplasmic reticulum membrane(GO:0097051) regulation of calcium ion-dependent exocytosis of neurotransmitter(GO:1903233)
0.0 0.1 GO:0060392 negative regulation of SMAD protein import into nucleus(GO:0060392)
0.0 0.1 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.0 0.2 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
0.0 0.1 GO:0006566 threonine metabolic process(GO:0006566)
0.0 0.1 GO:0006233 dTDP biosynthetic process(GO:0006233) dTDP metabolic process(GO:0046072)
0.0 0.3 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
0.0 0.1 GO:0090650 response to oxygen-glucose deprivation(GO:0090649) cellular response to oxygen-glucose deprivation(GO:0090650)
0.0 0.1 GO:0002940 tRNA N2-guanine methylation(GO:0002940)
0.0 0.1 GO:0043973 histone H3-K4 acetylation(GO:0043973)
0.0 0.1 GO:0030200 heparan sulfate proteoglycan catabolic process(GO:0030200)
0.0 0.1 GO:1902990 mitotic telomere maintenance via semi-conservative replication(GO:1902990)
0.0 0.1 GO:0032066 nucleolus to nucleoplasm transport(GO:0032066)
0.0 0.1 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.0 0.1 GO:0060160 negative regulation of dopamine receptor signaling pathway(GO:0060160)
0.0 0.1 GO:0030961 peptidyl-arginine hydroxylation(GO:0030961)
0.0 0.1 GO:1902951 negative regulation of dendritic spine maintenance(GO:1902951)
0.0 0.1 GO:0061762 CAMKK-AMPK signaling cascade(GO:0061762)
0.0 0.1 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269) leading strand elongation(GO:0006272)
0.0 0.1 GO:0035616 histone H2B conserved C-terminal lysine deubiquitination(GO:0035616)
0.0 0.3 GO:0071294 cellular response to zinc ion(GO:0071294)
0.0 0.1 GO:0006776 vitamin A metabolic process(GO:0006776)
0.0 0.1 GO:1904783 positive regulation of NMDA glutamate receptor activity(GO:1904783)
0.0 0.1 GO:2000825 positive regulation of androgen receptor activity(GO:2000825)
0.0 0.1 GO:0003376 sphingosine-1-phosphate signaling pathway(GO:0003376)
0.0 0.1 GO:0002485 antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway(GO:0002484) antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent(GO:0002485)
0.0 0.0 GO:0060671 epithelial cell differentiation involved in embryonic placenta development(GO:0060671) epithelial cell morphogenesis involved in placental branching(GO:0060672)
0.0 0.1 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.0 0.1 GO:0051684 maintenance of Golgi location(GO:0051684)
0.0 0.2 GO:0090315 negative regulation of protein targeting to membrane(GO:0090315)
0.0 0.1 GO:0042796 snRNA transcription from RNA polymerase III promoter(GO:0042796)
0.0 0.1 GO:0015755 fructose transport(GO:0015755)
0.0 0.2 GO:0032000 positive regulation of fatty acid beta-oxidation(GO:0032000)
0.0 0.1 GO:0042256 mature ribosome assembly(GO:0042256)
0.0 0.0 GO:0016240 autophagosome docking(GO:0016240)
0.0 0.0 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.0 0.1 GO:0002188 translation reinitiation(GO:0002188)
0.0 0.3 GO:0015701 bicarbonate transport(GO:0015701)
0.0 0.0 GO:1904924 negative regulation of mitophagy in response to mitochondrial depolarization(GO:1904924)
0.0 0.1 GO:0038026 reelin-mediated signaling pathway(GO:0038026)
0.0 0.1 GO:0031293 membrane protein intracellular domain proteolysis(GO:0031293)
0.0 0.0 GO:0040030 regulation of molecular function, epigenetic(GO:0040030)
0.0 0.1 GO:2000767 positive regulation of cytoplasmic translation(GO:2000767)
0.0 0.0 GO:1904479 negative regulation of intestinal absorption(GO:1904479)
0.0 0.0 GO:0070904 L-ascorbic acid transport(GO:0015882) transepithelial L-ascorbic acid transport(GO:0070904)
0.0 0.0 GO:0035521 monoubiquitinated histone deubiquitination(GO:0035521) monoubiquitinated histone H2A deubiquitination(GO:0035522)
0.0 0.2 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.1 GO:0045852 pH elevation(GO:0045852) intracellular pH elevation(GO:0051454)
0.0 0.1 GO:1902963 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.0 0.2 GO:0010529 regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529)
0.0 0.0 GO:0051030 snRNA transport(GO:0051030)
0.0 0.3 GO:0006744 ubiquinone biosynthetic process(GO:0006744)
0.0 0.1 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 0.0 GO:0060697 positive regulation of phospholipid catabolic process(GO:0060697)
0.0 0.1 GO:0044375 regulation of peroxisome size(GO:0044375)
0.0 0.1 GO:0000301 retrograde transport, vesicle recycling within Golgi(GO:0000301)
0.0 0.3 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 0.1 GO:0089700 protein kinase D signaling(GO:0089700)
0.0 0.1 GO:0038028 insulin receptor signaling pathway via phosphatidylinositol 3-kinase(GO:0038028)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0044279 other organism cell membrane(GO:0044218) other organism membrane(GO:0044279)
0.1 0.2 GO:0045251 mitochondrial electron transfer flavoprotein complex(GO:0017133) electron transfer flavoprotein complex(GO:0045251)
0.0 0.4 GO:0005766 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0 0.1 GO:0070992 translation initiation complex(GO:0070992)
0.0 0.1 GO:0098553 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.0 0.1 GO:0033596 TSC1-TSC2 complex(GO:0033596)
0.0 0.4 GO:0035686 sperm fibrous sheath(GO:0035686)
0.0 0.1 GO:0070876 SOSS complex(GO:0070876)
0.0 0.2 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.0 0.1 GO:0005927 muscle tendon junction(GO:0005927)
0.0 0.1 GO:1990745 EARP complex(GO:1990745)
0.0 0.1 GO:0005786 signal recognition particle, endoplasmic reticulum targeting(GO:0005786)
0.0 0.1 GO:0005964 phosphorylase kinase complex(GO:0005964)
0.0 0.0 GO:0097543 ciliary inversin compartment(GO:0097543)
0.0 0.1 GO:0010009 cytoplasmic side of endosome membrane(GO:0010009)
0.0 0.1 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 0.1 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750)
0.0 0.0 GO:0031417 NatC complex(GO:0031417)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:1990698 palmitoleoyltransferase activity(GO:1990698)
0.0 0.1 GO:0004418 hydroxymethylbilane synthase activity(GO:0004418)
0.0 0.3 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.0 0.2 GO:0005093 Rab GDP-dissociation inhibitor activity(GO:0005093)
0.0 0.1 GO:0016501 prostacyclin receptor activity(GO:0016501)
0.0 0.2 GO:0047844 deoxycytidine deaminase activity(GO:0047844)
0.0 0.1 GO:0080130 L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.0 0.4 GO:0004459 L-lactate dehydrogenase activity(GO:0004459)
0.0 0.2 GO:0070568 guanylyltransferase activity(GO:0070568)
0.0 0.1 GO:0004793 threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.0 0.1 GO:0008169 C-methyltransferase activity(GO:0008169)
0.0 0.1 GO:0015152 glucose-6-phosphate transmembrane transporter activity(GO:0015152)
0.0 0.1 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.0 0.2 GO:0004782 sulfinoalanine decarboxylase activity(GO:0004782)
0.0 0.1 GO:0015057 thrombin receptor activity(GO:0015057)
0.0 0.1 GO:0036080 GDP-fucose transmembrane transporter activity(GO:0005457) purine nucleotide-sugar transmembrane transporter activity(GO:0036080)
0.0 0.1 GO:0008160 protein tyrosine phosphatase activator activity(GO:0008160)
0.0 0.1 GO:0038025 reelin receptor activity(GO:0038025)
0.0 0.2 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.0 0.1 GO:0004798 thymidylate kinase activity(GO:0004798)
0.0 0.1 GO:0004174 electron-transferring-flavoprotein dehydrogenase activity(GO:0004174) oxidoreductase activity, acting on the CH-NH group of donors, quinone or similar compound as acceptor(GO:0016649)
0.0 0.1 GO:0015183 L-aspartate transmembrane transporter activity(GO:0015183)
0.0 0.2 GO:0005087 Ran guanyl-nucleotide exchange factor activity(GO:0005087)
0.0 0.1 GO:0042610 CD8 receptor binding(GO:0042610)
0.0 0.7 GO:0001530 lipopolysaccharide binding(GO:0001530)
0.0 0.1 GO:0046624 sphingolipid transporter activity(GO:0046624)
0.0 0.1 GO:0070976 TIR domain binding(GO:0070976)
0.0 0.1 GO:0070336 forked DNA-dependent helicase activity(GO:0061749) flap-structured DNA binding(GO:0070336)
0.0 0.3 GO:0031957 fatty acid transporter activity(GO:0015245) very long-chain fatty acid-CoA ligase activity(GO:0031957)
0.0 0.1 GO:0005171 hepatocyte growth factor receptor binding(GO:0005171)
0.0 0.1 GO:0016880 acid-ammonia (or amide) ligase activity(GO:0016880)
0.0 0.1 GO:0004614 phosphoglucomutase activity(GO:0004614)
0.0 0.1 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.0 0.1 GO:0017099 very-long-chain-acyl-CoA dehydrogenase activity(GO:0017099)
0.0 0.1 GO:0005353 fructose transmembrane transporter activity(GO:0005353) uniporter activity(GO:0015292)
0.0 0.3 GO:0070403 NAD+ binding(GO:0070403)
0.0 0.1 GO:0032767 copper-dependent protein binding(GO:0032767)
0.0 0.1 GO:0000010 trans-hexaprenyltranstransferase activity(GO:0000010) trans-octaprenyltranstransferase activity(GO:0050347)
0.0 0.3 GO:0008510 sodium:bicarbonate symporter activity(GO:0008510)
0.0 0.1 GO:0008802 betaine-aldehyde dehydrogenase activity(GO:0008802)
0.0 0.0 GO:0001132 RNA polymerase II transcription factor activity, TBP-class protein binding, involved in preinitiation complex assembly(GO:0001129) RNA polymerase II transcription factor activity, TBP-class protein binding(GO:0001132)
0.0 0.1 GO:0003953 NAD+ nucleosidase activity(GO:0003953)
0.0 0.1 GO:0036478 tyrosine 3-monooxygenase activator activity(GO:0036470) L-dopa decarboxylase activator activity(GO:0036478)
0.0 0.1 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.0 0.0 GO:0030622 U4atac snRNA binding(GO:0030622)
0.0 0.1 GO:0004161 dimethylallyltranstransferase activity(GO:0004161) geranyltranstransferase activity(GO:0004337)
0.0 0.1 GO:0004689 phosphorylase kinase activity(GO:0004689)
0.0 0.1 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0 0.1 GO:0042500 aspartic endopeptidase activity, intramembrane cleaving(GO:0042500)
0.0 0.2 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.0 0.1 GO:0048495 Roundabout binding(GO:0048495)
0.0 0.0 GO:0008520 L-ascorbate:sodium symporter activity(GO:0008520) L-ascorbic acid transporter activity(GO:0015229) sodium-dependent L-ascorbate transmembrane transporter activity(GO:0070890)
0.0 0.1 GO:0015288 porin activity(GO:0015288)
0.0 0.1 GO:0008607 phosphorylase kinase regulator activity(GO:0008607)
0.0 0.1 GO:0031750 D3 dopamine receptor binding(GO:0031750)
0.0 0.0 GO:0004667 prostaglandin-D synthase activity(GO:0004667)
0.0 0.1 GO:0015232 heme transporter activity(GO:0015232)
0.0 0.0 GO:0047223 beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,3-N-acetylglucosaminyltransferase activity(GO:0047223)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 PID P38 GAMMA DELTA PATHWAY Signaling mediated by p38-gamma and p38-delta

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.3 REACTOME PYRUVATE METABOLISM Genes involved in Pyruvate metabolism
0.0 0.7 REACTOME LATENT INFECTION OF HOMO SAPIENS WITH MYCOBACTERIUM TUBERCULOSIS Genes involved in Latent infection of Homo sapiens with Mycobacterium tuberculosis
0.0 0.2 REACTOME SYNTHESIS OF SUBSTRATES IN N GLYCAN BIOSYTHESIS Genes involved in Synthesis of substrates in N-glycan biosythesis
0.0 0.4 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.2 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation