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avrg: GFI1 WT vs 36n/n vs KD

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Results for Etv6

Z-value: 1.62

Motif logo

Transcription factors associated with Etv6

Gene Symbol Gene ID Gene Info
ENSMUSG00000030199.17 ets variant 6

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Etv6mm39_v1_chr6_+_134012602_134012683-0.701.9e-01Click!

Activity profile of Etv6 motif

Sorted Z-values of Etv6 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr3_-_94794256 0.83 ENSMUST00000005923.7
proteasome (prosome, macropain) subunit, beta type 4
chr2_+_130266253 0.72 ENSMUST00000128994.8
ENSMUST00000028900.11
VSP16 CORVET/HOPS core subunit
chr1_-_133537953 0.65 ENSMUST00000164574.2
ENSMUST00000166291.8
ENSMUST00000164096.2
ENSMUST00000166915.8
small nuclear ribonucleoprotein E
chr8_-_73324877 0.58 ENSMUST00000058733.9
ENSMUST00000167290.8
small integral membrane protein 7
chr13_+_4241149 0.57 ENSMUST00000021634.4
aldo-keto reductase family 1, member C13
chr11_-_35725317 0.52 ENSMUST00000018992.4
arginyl-tRNA synthetase
chr7_+_18883647 0.50 ENSMUST00000049294.4
small nuclear ribonucleoprotein D2
chr4_+_118478357 0.48 ENSMUST00000147373.2
EBNA1 binding protein 2
chr11_+_58221538 0.47 ENSMUST00000116376.9
SH3 binding domain protein 5 like
chr13_-_58276353 0.47 ENSMUST00000007980.7
heterogeneous nuclear ribonucleoprotein A0
chr2_+_179899166 0.47 ENSMUST00000059080.7
ribosomal protein S21
chr9_+_46184362 0.46 ENSMUST00000156440.8
ENSMUST00000114552.4
ZPR1 zinc finger
chr2_-_90735171 0.45 ENSMUST00000005647.4
NADH:ubiquinone oxidoreductase core subunit S3
chr15_-_85695855 0.45 ENSMUST00000134631.8
ENSMUST00000154814.2
ENSMUST00000071876.13
ENSMUST00000150995.8
cysteine rich, DPF motif domain containing 1
chrX_-_168103266 0.45 ENSMUST00000033717.9
ENSMUST00000112115.2
holocytochrome c synthetase
chr6_-_120799641 0.45 ENSMUST00000205049.3
ATPase, H+ transporting, lysosomal V1 subunit E1
chr7_-_45083688 0.45 ENSMUST00000210439.2
RuvB-like protein 2
chr19_+_8919228 0.43 ENSMUST00000096240.3
metastasis-associated gene family, member 2
chr14_-_30723549 0.43 ENSMUST00000226782.2
ENSMUST00000186131.7
ENSMUST00000228767.2
signal peptidase complex subunit 1 homolog (S. cerevisiae)
chr6_-_113717689 0.42 ENSMUST00000032440.6
SEC13 homolog, nuclear pore and COPII coat complex component
chr15_-_57755753 0.41 ENSMUST00000022993.7
Der1-like domain family, member 1
chr8_+_85583611 0.41 ENSMUST00000003906.13
ENSMUST00000109754.2
phenylalanyl-tRNA synthetase, alpha subunit
chrX_-_133442596 0.40 ENSMUST00000054213.5
translocase of inner mitochondrial membrane 8A1
chr9_-_78396407 0.40 ENSMUST00000154207.8
eukaryotic translation elongation factor 1 alpha 1
chr11_+_58221569 0.40 ENSMUST00000073128.7
SH3 binding domain protein 5 like
chr10_+_130158737 0.39 ENSMUST00000217702.2
ENSMUST00000042586.10
ENSMUST00000218605.2
thymocyte expressed, positive selection associated 1
chr17_+_46421908 0.38 ENSMUST00000024763.10
ENSMUST00000123646.2
mitochondrial ribosomal protein S18A
chr11_-_119190830 0.38 ENSMUST00000106253.2
eukaryotic translation initiation factor 4A3
chr17_+_28059129 0.37 ENSMUST00000233657.2
U1 small nuclear ribonucleoprotein C
chr3_-_65300000 0.37 ENSMUST00000029414.12
signal sequence receptor, gamma
chr4_-_116664729 0.36 ENSMUST00000106455.8
ENSMUST00000030451.10
target of EGR1, member 1 (nuclear)
chr6_-_120799672 0.36 ENSMUST00000019354.11
ATPase, H+ transporting, lysosomal V1 subunit E1
chr14_-_30723292 0.35 ENSMUST00000228736.2
ENSMUST00000226374.2
signal peptidase complex subunit 1 homolog (S. cerevisiae)
chr4_+_118266526 0.35 ENSMUST00000084319.11
ENSMUST00000106384.10
ENSMUST00000126089.8
ENSMUST00000073881.8
ENSMUST00000019229.15
mediator complex subunit 8
chr10_+_80008768 0.35 ENSMUST00000041882.7
family with sequence similarity 174, member C
chr8_+_12965876 0.35 ENSMUST00000110876.9
ENSMUST00000110879.9
mcf.2 transforming sequence-like
chr14_-_101877870 0.35 ENSMUST00000168587.3
COMM domain containing 6
chr17_+_26882171 0.35 ENSMUST00000236346.2
ATPase, H+ transporting, lysosomal V0 subunit E
chr7_+_81412695 0.34 ENSMUST00000133034.2
RNA guanine-7 methyltransferase activating subunit
chr11_-_120515799 0.34 ENSMUST00000106183.3
ENSMUST00000080202.12
sirtuin 7
chr9_-_22028370 0.33 ENSMUST00000213233.2
ELF1 homolog, elongation factor 1
chr13_-_95511837 0.33 ENSMUST00000022189.9
angiogenic factor with G patch and FHA domains 1
chr5_-_110928436 0.33 ENSMUST00000149208.2
ENSMUST00000031483.15
ENSMUST00000086643.12
ENSMUST00000170468.8
ENSMUST00000031481.13
pseudouridine synthase 1
chr4_+_118266582 0.33 ENSMUST00000144577.2
mediator complex subunit 8
chr9_-_21061196 0.32 ENSMUST00000215296.2
ENSMUST00000019615.11
cell division cycle 37
chr7_-_105460172 0.32 ENSMUST00000033170.7
ENSMUST00000176498.2
ENSMUST00000176887.2
ENSMUST00000124482.3
mitochondrial ribosomal protein L17
chr11_+_106146966 0.32 ENSMUST00000021049.9
protease (prosome, macropain) 26S subunit, ATPase 5
chr19_+_6135013 0.32 ENSMUST00000025704.3
cell division cycle associated 5
chr18_+_34994253 0.32 ENSMUST00000165033.2
early growth response 1
chr5_-_139812592 0.31 ENSMUST00000182602.2
ENSMUST00000031531.14
proteasome (prosome, macropain) assembly chaperone 3
chr3_+_157239988 0.31 ENSMUST00000029831.16
ENSMUST00000106057.8
zinc finger, RAN-binding domain containing 2
chr12_-_55126882 0.31 ENSMUST00000021406.6
RIKEN cDNA 2700097O09 gene
chr19_+_8849000 0.31 ENSMUST00000096255.7
UBX domain protein 1
chr6_-_120799500 0.31 ENSMUST00000204699.2
ATPase, H+ transporting, lysosomal V1 subunit E1
chr11_-_119190896 0.31 ENSMUST00000026667.15
eukaryotic translation initiation factor 4A3
chr2_-_93841062 0.30 ENSMUST00000040005.13
ENSMUST00000126378.8
alkB homolog 3, alpha-ketoglutarate-dependent dioxygenase
chr7_+_81412673 0.30 ENSMUST00000042166.11
RNA guanine-7 methyltransferase activating subunit
chr9_+_107440445 0.30 ENSMUST00000010198.5
tumor suppressor 2, mitochondrial calcium regulator
chr12_+_55276953 0.29 ENSMUST00000218879.2
signal recognition particle 54C
chr17_+_28059099 0.29 ENSMUST00000233752.2
U1 small nuclear ribonucleoprotein C
chr15_+_58805605 0.29 ENSMUST00000022980.5
NADH:ubiquinone oxidoreductase subunit B9
chr10_+_128641663 0.28 ENSMUST00000218511.2
DnaJ heat shock protein family (Hsp40) member C14
chr3_-_65299967 0.28 ENSMUST00000119896.2
signal sequence receptor, gamma
chr8_-_22888604 0.28 ENSMUST00000033871.8
solute carrier family 25 (mitochondrial carrier ornithine transporter), member 15
chr9_+_107440484 0.28 ENSMUST00000193418.2
tumor suppressor 2, mitochondrial calcium regulator
chr19_-_44994824 0.28 ENSMUST00000097715.4
mitochondrial ribosomal protein L43
chr7_-_45084012 0.28 ENSMUST00000107771.12
ENSMUST00000211666.2
RuvB-like protein 2
chr3_+_103875261 0.27 ENSMUST00000117150.8
putative homeodomain transcription factor 1
chr7_+_126832399 0.27 ENSMUST00000056232.7
zinc finger protein 553
chr4_+_45297127 0.27 ENSMUST00000044673.9
ENSMUST00000144781.3
tRNA methyltransferase 10B
chr10_-_67120959 0.27 ENSMUST00000159002.2
ENSMUST00000077839.13
nuclear receptor binding factor 2
chrX_+_7750483 0.27 ENSMUST00000115663.10
ENSMUST00000096514.11
solute carrier family 35 (UDP-galactose transporter), member A2
chr10_-_30476658 0.27 ENSMUST00000019927.7
tRNA methyltransferase 11
chr4_-_98271469 0.26 ENSMUST00000143116.2
ENSMUST00000030292.12
ENSMUST00000102793.11
TM2 domain containing 1
chr2_+_29825427 0.26 ENSMUST00000019859.9
GLE1 RNA export mediator (yeast)
chr10_+_128641520 0.26 ENSMUST00000219508.2
ENSMUST00000026410.2
DnaJ heat shock protein family (Hsp40) member C14
chr14_-_101878106 0.26 ENSMUST00000100339.9
COMM domain containing 6
chr10_-_31485180 0.26 ENSMUST00000081989.8
ring finger protein 217
chr11_-_20062876 0.26 ENSMUST00000000137.8
ARP2 actin-related protein 2
chrX_+_7750558 0.26 ENSMUST00000208640.2
ENSMUST00000207114.2
ENSMUST00000208633.2
ENSMUST00000208397.2
ENSMUST00000153620.3
ENSMUST00000123277.8
solute carrier family 35 (UDP-galactose transporter), member A2
chr7_+_126832215 0.25 ENSMUST00000106312.4
zinc finger protein 553
chr4_+_116664911 0.25 ENSMUST00000102699.8
ENSMUST00000130359.8
mutY DNA glycosylase
chr19_-_5416339 0.25 ENSMUST00000170010.3
BAF nuclear assembly factor 1
chr17_+_47022384 0.25 ENSMUST00000002840.9
peroxisomal biogenesis factor 6
chr17_-_26063391 0.25 ENSMUST00000176591.8
ras homolog family member T2
chr5_+_24791719 0.25 ENSMUST00000088295.9
ENSMUST00000121863.5
chondroitin polymerizing factor 2
chr11_+_88095222 0.24 ENSMUST00000118784.8
ENSMUST00000139170.8
ENSMUST00000107915.10
ENSMUST00000144070.3
mitochondrial ribosomal protein S23
chr15_+_79555272 0.24 ENSMUST00000127292.2
translocase of outer mitochondrial membrane 22
chr10_-_14581203 0.24 ENSMUST00000149485.2
ENSMUST00000154132.8
vesicle (multivesicular body) trafficking 1
chr2_-_30857858 0.24 ENSMUST00000028200.9
torsin family 1, member A (torsin A)
chrX_+_7750261 0.23 ENSMUST00000115660.12
solute carrier family 35 (UDP-galactose transporter), member A2
chr11_-_120348762 0.23 ENSMUST00000137632.2
ENSMUST00000044007.3
oxidoreductase like domain containing 1
chr11_+_120839288 0.23 ENSMUST00000070653.13
solute carrier family 16 (monocarboxylic acid transporters), member 3
chr15_+_76215488 0.23 ENSMUST00000172281.8
GPI anchor attachment protein 1
chr5_-_110417682 0.23 ENSMUST00000196381.2
ENSMUST00000059229.16
ENSMUST00000112505.9
phosphoglycerate mutase family member 5
chr8_+_107783502 0.23 ENSMUST00000034392.13
ENSMUST00000170962.3
NIP7, nucleolar pre-rRNA processing protein
chr11_+_87628356 0.23 ENSMUST00000093955.12
SPT4A, DSIF elongation factor subunit
chr10_-_80156337 0.23 ENSMUST00000020341.9
RIKEN cDNA 2310011J03 gene
chr2_+_48704121 0.23 ENSMUST00000063886.4
activin receptor IIA
chr4_-_124744943 0.23 ENSMUST00000185036.2
RIKEN cDNA 1110065P20 gene
chr13_-_4329421 0.23 ENSMUST00000021632.5
aldo-keto reductase family 1, member C12
chr11_+_88095206 0.22 ENSMUST00000024486.14
mitochondrial ribosomal protein S23
chr15_-_85695810 0.22 ENSMUST00000144067.8
cysteine rich, DPF motif domain containing 1
chr8_-_108315024 0.22 ENSMUST00000044106.6
proteasome (prosome, macropain) 26S subunit, non-ATPase, 7
chr3_+_89337568 0.22 ENSMUST00000060061.11
pygopus 2
chr19_+_8848924 0.22 ENSMUST00000238036.2
UBX domain protein 1
chr9_+_99457829 0.21 ENSMUST00000066650.12
ENSMUST00000148987.8
debranching RNA lariats 1
chr1_+_58625539 0.21 ENSMUST00000027193.9
NADH:ubiquinone oxidoreductase subunit B3
chr16_+_64672334 0.21 ENSMUST00000067744.8
CGG triplet repeat binding protein 1
chr12_+_104998895 0.21 ENSMUST00000223244.2
ENSMUST00000021522.5
glutaredoxin 5
chr8_+_110944575 0.21 ENSMUST00000056972.6
cap methyltransferase 2
chr12_+_102724223 0.21 ENSMUST00000046404.8
ubiquitin protein ligase E3 component n-recognin 7 (putative)
chr15_+_5215000 0.21 ENSMUST00000118193.8
ENSMUST00000022751.15
tetratricopeptide repeat domain 33
chr12_+_78908466 0.21 ENSMUST00000071230.8
eukaryotic translation initiation factor 2, subunit 1 alpha
chr11_+_61544085 0.21 ENSMUST00000004959.3
GRB2-related adaptor protein
chr11_+_119989736 0.21 ENSMUST00000106223.4
ENSMUST00000185558.2
NADH:ubiquinone oxidoreductase complex assembly factor 8
chr12_-_87435091 0.21 ENSMUST00000021424.5
serine palmitoyltransferase, long chain base subunit 2
chr15_+_76215431 0.20 ENSMUST00000023221.13
GPI anchor attachment protein 1
chr4_+_156028281 0.20 ENSMUST00000103175.8
ENSMUST00000166489.8
ENSMUST00000024056.10
ENSMUST00000136492.2
ENSMUST00000105583.9
ENSMUST00000152536.8
ENSMUST00000118192.8
ubiquitin-conjugating enzyme E2J 2
chr4_-_59438633 0.20 ENSMUST00000040166.14
ENSMUST00000107544.2
sushi domain containing 1
chr6_-_115785695 0.20 ENSMUST00000081840.6
ribosomal protein L32
chr2_-_145776934 0.20 ENSMUST00000001818.5
crooked neck pre-mRNA splicing factor 1
chr4_+_124960465 0.20 ENSMUST00000052183.7
Smad nuclear interacting protein 1
chr19_+_3332901 0.20 ENSMUST00000025745.10
ENSMUST00000025743.7
mitochondrial ribosomal protein L21
chr4_-_133005039 0.20 ENSMUST00000105907.9
transmembrane protein 222
chr12_+_55201889 0.20 ENSMUST00000110708.4
signal recognition particle 54B
chr1_+_75498162 0.20 ENSMUST00000027414.16
ENSMUST00000113553.2
serine/threonine kinase 11 interacting protein
chr4_+_107035615 0.20 ENSMUST00000128123.3
ENSMUST00000106753.3
transmembrane protein 59
chr19_-_27407206 0.20 ENSMUST00000076219.6
pumilio RNA-binding family member 3
chr11_+_96932379 0.20 ENSMUST00000001485.10
mitochondrial ribosomal protein L10
chr11_-_79853200 0.20 ENSMUST00000108241.8
ENSMUST00000043152.6
UTP6 small subunit processome component
chrX_+_99669343 0.19 ENSMUST00000048962.4
kinesin family member 4
chr3_+_157239740 0.19 ENSMUST00000106058.8
zinc finger, RAN-binding domain containing 2
chr17_-_50497682 0.19 ENSMUST00000044503.14
raftlin lipid raft linker 1
chr19_+_8848876 0.19 ENSMUST00000166407.9
UBX domain protein 1
chr2_-_132657891 0.19 ENSMUST00000039554.7
tRNA methyltransferase 6
chr5_-_149559636 0.19 ENSMUST00000201452.4
heat shock 105kDa/110kDa protein 1
chr12_+_55126999 0.18 ENSMUST00000220578.2
ENSMUST00000221655.2
signal recognition particle 54A
chr19_+_5416769 0.18 ENSMUST00000025759.9
eukaryotic translation initiation factor 1A domain containing
chr9_-_22028419 0.18 ENSMUST00000214394.2
ENSMUST00000013966.8
ELF1 homolog, elongation factor 1
chr8_-_78337297 0.18 ENSMUST00000141202.2
ENSMUST00000152168.8
transmembrane protein 184C
chr15_-_34443355 0.18 ENSMUST00000009039.6
ribosomal protein L30
chr14_+_55909692 0.18 ENSMUST00000002397.7
guanosine monophosphate reductase 2
chr18_+_31922173 0.18 ENSMUST00000025106.5
ENSMUST00000234146.2
polymerase (RNA) II (DNA directed) polypeptide D
chr4_+_118477994 0.18 ENSMUST00000030501.15
EBNA1 binding protein 2
chr6_-_88495835 0.18 ENSMUST00000032168.7
Sec61 alpha 1 subunit (S. cerevisiae)
chr4_-_48279543 0.17 ENSMUST00000030028.5
endoplasmic reticulum protein 44
chr19_+_44994905 0.17 ENSMUST00000026227.3
twinkle mtDNA helicase
chr5_-_149559667 0.17 ENSMUST00000074846.14
heat shock 105kDa/110kDa protein 1
chr10_+_128641398 0.17 ENSMUST00000217745.2
DnaJ heat shock protein family (Hsp40) member C14
chr11_-_115590318 0.17 ENSMUST00000106497.8
growth factor receptor bound protein 2
chr11_-_84710276 0.17 ENSMUST00000018549.8
mitochondrial rRNA methyltransferase 1
chr8_-_84059048 0.17 ENSMUST00000177594.8
ENSMUST00000053902.4
ELMO/CED-12 domain containing 2
chr1_-_125363272 0.16 ENSMUST00000178474.8
ARP3 actin-related protein 3
chr7_+_65693350 0.16 ENSMUST00000206065.2
predicted gene 45213
chr9_-_57552392 0.16 ENSMUST00000216934.2
c-src tyrosine kinase
chr7_+_79910948 0.16 ENSMUST00000117989.2
neugrin, neurite outgrowth associated
chr7_-_105393519 0.16 ENSMUST00000141116.2
TATA-box binding protein associated factor 10
chr2_-_93841152 0.16 ENSMUST00000111240.8
alkB homolog 3, alpha-ketoglutarate-dependent dioxygenase
chr14_+_55829165 0.16 ENSMUST00000019443.15
ring finger protein 31
chr5_+_147797258 0.16 ENSMUST00000031654.10
proteasome maturation protein
chr4_-_119177614 0.16 ENSMUST00000147077.8
ENSMUST00000056458.14
ENSMUST00000106321.9
ENSMUST00000106319.8
ENSMUST00000106317.2
ENSMUST00000106318.8
peptidyl prolyl isomerase H
chrX_-_93256244 0.16 ENSMUST00000113922.2
eukaryotic translation initiation factor 2, subunit 3, structural gene X-linked
chr1_-_36283326 0.15 ENSMUST00000046875.14
UDP-glucose glycoprotein glucosyltransferase 1
chr1_-_58625431 0.15 ENSMUST00000161000.2
ENSMUST00000161600.8
family with sequence similarity 126, member B
chr11_+_96932395 0.15 ENSMUST00000054252.5
mitochondrial ribosomal protein L10
chr11_-_16458069 0.15 ENSMUST00000109641.2
SEC61, gamma subunit
chr1_-_179373826 0.15 ENSMUST00000027769.6
transcription factor B2, mitochondrial
chr11_-_106146868 0.15 ENSMUST00000021048.7
FtsJ RNA methyltransferase homolog 3 (E. coli)
chr3_-_5641171 0.15 ENSMUST00000071280.8
ENSMUST00000195855.6
ENSMUST00000165309.8
ENSMUST00000164828.8
peroxisomal biogenesis factor 2
chr1_+_167135933 0.14 ENSMUST00000195015.6
transmembrane and coiled-coil domains 1
chr15_+_5215180 0.14 ENSMUST00000081640.12
tetratricopeptide repeat domain 33
chr11_+_94544593 0.14 ENSMUST00000025278.8
mitochondrial ribosomal protein L27
chr1_+_4878460 0.14 ENSMUST00000131119.2
lysophospholipase 1
chr2_+_152068729 0.14 ENSMUST00000099224.10
ENSMUST00000124791.8
ENSMUST00000133119.2
casein kinase 2, alpha 1 polypeptide
chr9_+_40103598 0.14 ENSMUST00000026693.14
ENSMUST00000168832.2
zinc finger protein 202
chr11_+_50101717 0.13 ENSMUST00000147468.8
mannoside acetylglucosaminyltransferase 4, isoenzyme B
chr18_+_12261798 0.13 ENSMUST00000025270.8
RIO kinase 3
chr5_+_124690908 0.13 ENSMUST00000071057.14
ENSMUST00000111438.2
DEAD box helicase 55
chr2_+_132528851 0.13 ENSMUST00000061891.11
shieldin complex subunit 1
chr4_-_41314877 0.13 ENSMUST00000030145.9
DDB1 and CUL4 associated factor 12
chrX_-_99669507 0.13 ENSMUST00000059099.7
PDZ domain containing 11
chr11_+_5905693 0.13 ENSMUST00000002818.9
YKT6 v-SNARE homolog (S. cerevisiae)
chr19_+_44551280 0.13 ENSMUST00000040455.5
hypoxia-inducible factor 1, alpha subunit inhibitor
chr19_+_4204605 0.13 ENSMUST00000061086.9
protein tyrosine phosphatase, receptor type, C polypeptide-associated protein
chr8_-_111573401 0.12 ENSMUST00000042012.7
splicing factor 3b, subunit 3
chr15_-_81931783 0.12 ENSMUST00000080622.9
SNU13 homolog, small nuclear ribonucleoprotein (U4/U6.U5)
chr6_+_124785621 0.12 ENSMUST00000047760.10
splA/ryanodine receptor domain and SOCS box containing 2
chr11_-_115590133 0.12 ENSMUST00000106499.8
growth factor receptor bound protein 2
chr1_+_4878046 0.12 ENSMUST00000027036.11
ENSMUST00000150971.8
ENSMUST00000119612.9
ENSMUST00000137887.8
ENSMUST00000115529.8
lysophospholipase 1
chr2_+_127050281 0.12 ENSMUST00000103220.4
small nuclear ribonucleoprotein 200 (U5)
chr4_-_136613498 0.12 ENSMUST00000046384.9
complement component 1, q subcomponent, beta polypeptide
chr7_-_80597479 0.12 ENSMUST00000026818.12
ENSMUST00000117383.8
ENSMUST00000119980.2
SEC11 homolog A, signal peptidase complex subunit
chr2_+_32425327 0.12 ENSMUST00000133512.2
ENSMUST00000048375.6
family with sequence similarity 102, member A
chr4_-_46389391 0.11 ENSMUST00000086563.11
ENSMUST00000030015.6
tRNA methyltransferase O
chr4_-_45320579 0.11 ENSMUST00000030003.10
exosome component 3
chr2_-_75808508 0.11 ENSMUST00000099995.5
tetratricopeptide repeat domain 30A2
chr13_+_20274708 0.11 ENSMUST00000072519.7
engulfment and cell motility 1
chr8_+_105066980 0.11 ENSMUST00000211885.2
CKLF-like MARVEL transmembrane domain containing 3
chr4_-_40948196 0.11 ENSMUST00000030125.5
ENSMUST00000108089.8
ENSMUST00000191273.7
BCL2-associated athanogene 1

Network of associatons between targets according to the STRING database.

First level regulatory network of Etv6

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0052572 interleukin-15 production(GO:0032618) response to immune response of other organism involved in symbiotic interaction(GO:0052564) response to host immune response(GO:0052572)
0.2 0.7 GO:1904569 regulation of selenocysteine incorporation(GO:1904569)
0.1 0.4 GO:0010387 COP9 signalosome assembly(GO:0010387)
0.1 0.7 GO:0071898 regulation of estrogen receptor binding(GO:0071898) negative regulation of estrogen receptor binding(GO:0071899)
0.1 0.3 GO:0042222 interleukin-1 biosynthetic process(GO:0042222)
0.1 0.5 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.1 0.7 GO:2000157 regulation of protein K48-linked deubiquitination(GO:1903093) negative regulation of protein K48-linked deubiquitination(GO:1903094) negative regulation of ubiquitin-specific protease activity(GO:2000157)
0.1 0.3 GO:0000066 mitochondrial ornithine transport(GO:0000066)
0.1 0.3 GO:0019043 establishment of viral latency(GO:0019043)
0.1 0.5 GO:0030576 Cajal body organization(GO:0030576) positive regulation of transcription involved in G1/S transition of mitotic cell cycle(GO:0071931)
0.1 0.6 GO:0016344 meiotic chromosome movement towards spindle pole(GO:0016344)
0.1 0.7 GO:0035542 regulation of SNARE complex assembly(GO:0035542)
0.1 0.3 GO:0045896 regulation of transcription during mitosis(GO:0045896) positive regulation of transcription during mitosis(GO:0045897)
0.1 0.3 GO:0016561 protein import into peroxisome matrix, translocation(GO:0016561)
0.1 0.7 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.1 0.4 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.1 0.5 GO:0016255 attachment of GPI anchor to protein(GO:0016255)
0.1 0.2 GO:0006391 transcription initiation from mitochondrial promoter(GO:0006391)
0.1 0.5 GO:0035553 oxidative single-stranded DNA demethylation(GO:0035552) oxidative single-stranded RNA demethylation(GO:0035553)
0.1 0.5 GO:1903751 regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903750) negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide(GO:1903751)
0.1 0.1 GO:0018307 enzyme active site formation(GO:0018307)
0.1 0.5 GO:0000447 endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000447)
0.1 0.5 GO:0090005 negative regulation of Golgi to plasma membrane protein transport(GO:0042997) negative regulation of establishment of protein localization to plasma membrane(GO:0090005)
0.1 0.2 GO:0006667 sphinganine metabolic process(GO:0006667)
0.1 0.3 GO:0034085 establishment of sister chromatid cohesion(GO:0034085) cohesin loading(GO:0071921) regulation of cohesin loading(GO:0071922)
0.1 1.0 GO:0006614 SRP-dependent cotranslational protein targeting to membrane(GO:0006614)
0.1 0.2 GO:0031990 mRNA export from nucleus in response to heat stress(GO:0031990)
0.1 0.2 GO:0046038 GMP catabolic process(GO:0046038)
0.1 0.2 GO:0046881 positive regulation of follicle-stimulating hormone secretion(GO:0046881)
0.1 0.2 GO:0000451 rRNA 2'-O-methylation(GO:0000451)
0.1 0.3 GO:1990481 mRNA pseudouridine synthesis(GO:1990481)
0.1 1.0 GO:0006465 signal peptide processing(GO:0006465)
0.0 0.1 GO:0090285 negative regulation of protein glycosylation in Golgi(GO:0090285)
0.0 0.1 GO:0042264 peptidyl-aspartic acid hydroxylation(GO:0042264)
0.0 0.1 GO:0019427 acetate biosynthetic process(GO:0019413) acetyl-CoA biosynthetic process from acetate(GO:0019427) propionate biosynthetic process(GO:0019542)
0.0 0.8 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.0 0.3 GO:0071985 multivesicular body sorting pathway(GO:0071985)
0.0 1.5 GO:0015991 ATP hydrolysis coupled proton transport(GO:0015991)
0.0 0.5 GO:0090503 RNA phosphodiester bond hydrolysis, exonucleolytic(GO:0090503)
0.0 0.2 GO:0036451 cap mRNA methylation(GO:0036451)
0.0 0.2 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.0 0.2 GO:0051940 regulation of dopamine uptake involved in synaptic transmission(GO:0051584) regulation of catecholamine uptake involved in synaptic transmission(GO:0051940)
0.0 0.1 GO:0002946 tRNA C5-cytosine methylation(GO:0002946)
0.0 0.3 GO:0006449 regulation of translational termination(GO:0006449)
0.0 0.1 GO:0032201 telomere maintenance via semi-conservative replication(GO:0032201) mitotic telomere maintenance via semi-conservative replication(GO:1902990) negative regulation of t-circle formation(GO:1904430)
0.0 0.1 GO:1903361 protein localization to basolateral plasma membrane(GO:1903361)
0.0 0.1 GO:0010847 regulation of chromatin assembly(GO:0010847)
0.0 0.0 GO:0072194 kidney smooth muscle tissue development(GO:0072194)
0.0 0.2 GO:0009249 protein lipoylation(GO:0009249)
0.0 0.3 GO:0090261 positive regulation of inclusion body assembly(GO:0090261)
0.0 0.3 GO:0006983 ER overload response(GO:0006983)
0.0 0.1 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.0 0.1 GO:0060800 regulation of cell differentiation involved in embryonic placenta development(GO:0060800)
0.0 0.3 GO:0060334 regulation of interferon-gamma-mediated signaling pathway(GO:0060334)
0.0 0.5 GO:0070935 3'-UTR-mediated mRNA stabilization(GO:0070935)
0.0 0.2 GO:0032596 protein transport into membrane raft(GO:0032596)
0.0 0.2 GO:0045040 protein import into mitochondrial outer membrane(GO:0045040)
0.0 0.2 GO:0035879 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
0.0 0.2 GO:0034214 protein hexamerization(GO:0034214)
0.0 0.2 GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.0 0.3 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.2 GO:0051256 mitotic spindle midzone assembly(GO:0051256)
0.0 0.1 GO:0000466 maturation of 5.8S rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000466)
0.0 0.1 GO:0000479 endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000479)
0.0 0.3 GO:0060670 branching involved in labyrinthine layer morphogenesis(GO:0060670)
0.0 0.4 GO:0048096 chromatin-mediated maintenance of transcription(GO:0048096)
0.0 0.4 GO:0017004 cytochrome complex assembly(GO:0017004)
0.0 0.0 GO:0007228 positive regulation of hh target transcription factor activity(GO:0007228)
0.0 0.1 GO:0000492 box C/D snoRNP assembly(GO:0000492)
0.0 0.1 GO:0036092 phosphatidylinositol-3-phosphate biosynthetic process(GO:0036092)
0.0 0.2 GO:0023035 CD40 signaling pathway(GO:0023035)
0.0 0.4 GO:0030970 retrograde protein transport, ER to cytosol(GO:0030970)
0.0 0.2 GO:0016558 protein import into peroxisome matrix(GO:0016558)
0.0 0.8 GO:0032543 mitochondrial translation(GO:0032543)
0.0 0.5 GO:0000387 spliceosomal snRNP assembly(GO:0000387)
0.0 0.1 GO:2000672 negative regulation of motor neuron apoptotic process(GO:2000672)
0.0 0.2 GO:0070365 hepatocyte differentiation(GO:0070365)
0.0 0.9 GO:0042273 ribosomal large subunit biogenesis(GO:0042273)
0.0 0.4 GO:0097031 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.6 GO:0061099 negative regulation of protein tyrosine kinase activity(GO:0061099)
0.0 0.8 GO:0006805 xenobiotic metabolic process(GO:0006805)
0.0 0.1 GO:0071569 protein ufmylation(GO:0071569)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.1 1.0 GO:0005787 signal peptidase complex(GO:0005787)
0.1 1.2 GO:0005687 U4 snRNP(GO:0005687)
0.1 0.7 GO:0033263 CORVET complex(GO:0033263)
0.1 0.7 GO:0097255 R2TP complex(GO:0097255)
0.1 0.5 GO:0042765 GPI-anchor transamidase complex(GO:0042765)
0.1 0.2 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.1 0.2 GO:0043614 multi-eIF complex(GO:0043614)
0.1 0.8 GO:0000243 commitment complex(GO:0000243)
0.1 0.8 GO:0048500 signal recognition particle(GO:0048500)
0.1 0.2 GO:1902560 GMP reductase complex(GO:1902560)
0.1 0.5 GO:0097504 Gemini of coiled bodies(GO:0097504)
0.1 0.3 GO:0044614 nuclear pore cytoplasmic filaments(GO:0044614)
0.1 0.2 GO:0071001 U4/U6 snRNP(GO:0071001)
0.0 0.7 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 0.3 GO:0035032 phosphatidylinositol 3-kinase complex, class III(GO:0035032)
0.0 0.8 GO:0005885 Arp2/3 protein complex(GO:0005885)
0.0 0.6 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.4 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.1 GO:0044753 amphisome(GO:0044753)
0.0 0.9 GO:0005839 proteasome core complex(GO:0005839)
0.0 0.9 GO:0033178 proton-transporting two-sector ATPase complex, catalytic domain(GO:0033178)
0.0 0.2 GO:0042406 extrinsic component of endoplasmic reticulum membrane(GO:0042406)
0.0 0.3 GO:0070436 Grb2-EGFR complex(GO:0070436)
0.0 0.3 GO:0031595 nuclear proteasome complex(GO:0031595)
0.0 0.2 GO:0000125 PCAF complex(GO:0000125)
0.0 0.2 GO:0071797 LUBAC complex(GO:0071797)
0.0 0.2 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.0 0.3 GO:0008278 cohesin complex(GO:0008278)
0.0 1.0 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 0.2 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.0 0.2 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 0.4 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 0.9 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.1 GO:1990622 CHOP-C/EBP complex(GO:0036488) CHOP-ATF3 complex(GO:1990622)
0.0 0.1 GO:0098843 postsynaptic endocytic zone(GO:0098843)
0.0 0.2 GO:0031211 serine C-palmitoyltransferase complex(GO:0017059) endoplasmic reticulum palmitoyltransferase complex(GO:0031211)
0.0 0.2 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 0.6 GO:0016581 NuRD complex(GO:0016581) CHD-type complex(GO:0090545)
0.0 0.2 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 1.3 GO:0000315 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.1 GO:0097441 basilar dendrite(GO:0097441)
0.0 0.2 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)
0.0 1.0 GO:0005747 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)
0.0 0.7 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.7 GO:0016592 mediator complex(GO:0016592)
0.0 0.1 GO:0034657 GID complex(GO:0034657)
0.0 0.1 GO:0000931 gamma-tubulin large complex(GO:0000931) gamma-tubulin ring complex(GO:0008274)
0.0 0.1 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.0 0.2 GO:0005838 proteasome regulatory particle(GO:0005838)
0.0 0.1 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.1 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.1 GO:0070876 SOSS complex(GO:0070876)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.2 0.7 GO:0030627 pre-mRNA 5'-splice site binding(GO:0030627)
0.2 0.7 GO:0071796 K6-linked polyubiquitin binding(GO:0071796)
0.2 0.5 GO:0051747 cytosine C-5 DNA demethylase activity(GO:0051747)
0.1 1.2 GO:1990446 U1 snRNP binding(GO:1990446)
0.1 0.3 GO:0031531 thyrotropin-releasing hormone receptor binding(GO:0031531)
0.1 0.5 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.1 0.3 GO:0034739 histone deacetylase activity (H4-K16 specific)(GO:0034739)
0.1 1.0 GO:0035368 selenocysteine insertion sequence binding(GO:0035368)
0.1 0.5 GO:0003923 GPI-anchor transamidase activity(GO:0003923)
0.1 0.6 GO:0043141 ATP-dependent 5'-3' DNA helicase activity(GO:0043141)
0.1 0.4 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.1 0.3 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.1 0.4 GO:0030942 endoplasmic reticulum signal peptide binding(GO:0030942)
0.1 0.3 GO:0016435 rRNA (guanine) methyltransferase activity(GO:0016435)
0.1 0.2 GO:0003920 GMP reductase activity(GO:0003920) oxidoreductase activity, acting on NAD(P)H, nitrogenous group as acceptor(GO:0016657)
0.1 0.1 GO:0016426 tRNA (adenine) methyltransferase activity(GO:0016426)
0.1 0.3 GO:0000064 L-ornithine transmembrane transporter activity(GO:0000064)
0.1 0.6 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.1 0.3 GO:0004809 tRNA (guanine-N2-)-methyltransferase activity(GO:0004809)
0.1 1.1 GO:0008553 hydrogen-exporting ATPase activity, phosphorylative mechanism(GO:0008553)
0.1 0.3 GO:0000700 mismatch base pair DNA N-glycosylase activity(GO:0000700)
0.0 0.1 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.0 0.3 GO:0044729 hemi-methylated DNA-binding(GO:0044729)
0.0 0.2 GO:0043139 5'-3' DNA helicase activity(GO:0043139)
0.0 0.1 GO:0030622 U4atac snRNA binding(GO:0030622)
0.0 0.2 GO:0004758 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.0 0.3 GO:0009019 tRNA (guanine-N1-)-methyltransferase activity(GO:0009019)
0.0 0.2 GO:0004483 mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483)
0.0 0.9 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.0 0.1 GO:0004819 glutamine-tRNA ligase activity(GO:0004819)
0.0 0.8 GO:0004033 aldo-keto reductase (NADP) activity(GO:0004033)
0.0 0.1 GO:0050347 trans-hexaprenyltranstransferase activity(GO:0000010) trans-octaprenyltranstransferase activity(GO:0050347)
0.0 0.2 GO:0017002 activin-activated receptor activity(GO:0017002)
0.0 0.4 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.2 GO:0015129 lactate transmembrane transporter activity(GO:0015129)
0.0 0.3 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.1 GO:0015140 malate transmembrane transporter activity(GO:0015140)
0.0 0.1 GO:0003987 acetate-CoA ligase activity(GO:0003987)
0.0 0.1 GO:0016748 succinyltransferase activity(GO:0016748)
0.0 0.4 GO:0036442 hydrogen-exporting ATPase activity(GO:0036442)
0.0 0.7 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.2 GO:0015266 protein channel activity(GO:0015266)
0.0 0.4 GO:0042288 MHC class I protein binding(GO:0042288)
0.0 0.3 GO:0005168 neurotrophin TRKA receptor binding(GO:0005168)
0.0 0.1 GO:0089720 caspase binding(GO:0089720)
0.0 0.3 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.1 GO:0071532 ankyrin repeat binding(GO:0071532)
0.0 0.4 GO:0003746 translation elongation factor activity(GO:0003746)
0.0 0.4 GO:0004535 poly(A)-specific ribonuclease activity(GO:0004535)
0.0 0.2 GO:0035251 UDP-glucosyltransferase activity(GO:0035251)
0.0 0.5 GO:0008137 NADH dehydrogenase (ubiquinone) activity(GO:0008137) NADH dehydrogenase (quinone) activity(GO:0050136)
0.0 0.6 GO:0051059 NF-kappaB binding(GO:0051059)
0.0 0.7 GO:0050780 dopamine receptor binding(GO:0050780)
0.0 0.3 GO:0043422 protein kinase B binding(GO:0043422)
0.0 2.5 GO:0003735 structural constituent of ribosome(GO:0003735)
0.0 0.1 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.6 GO:0031369 translation initiation factor binding(GO:0031369)
0.0 0.1 GO:0004792 thiosulfate sulfurtransferase activity(GO:0004792)
0.0 0.5 GO:0017091 AU-rich element binding(GO:0017091)
0.0 0.4 GO:0031492 nucleosomal DNA binding(GO:0031492)
0.0 0.1 GO:0016428 tRNA (cytosine-5-)-methyltransferase activity(GO:0016428)
0.0 0.2 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 0.5 GO:0003743 translation initiation factor activity(GO:0003743)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.0 PID MYC PATHWAY C-MYC pathway
0.0 0.5 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.4 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 0.6 REACTOME SLBP DEPENDENT PROCESSING OF REPLICATION DEPENDENT HISTONE PRE MRNAS Genes involved in SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs
0.0 1.0 REACTOME SYNTHESIS SECRETION AND INACTIVATION OF GIP Genes involved in Synthesis, Secretion, and Inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)
0.0 0.3 REACTOME APOBEC3G MEDIATED RESISTANCE TO HIV1 INFECTION Genes involved in APOBEC3G mediated resistance to HIV-1 infection
0.0 1.2 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling
0.0 1.0 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 1.4 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 1.0 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 0.3 REACTOME BASE FREE SUGAR PHOSPHATE REMOVAL VIA THE SINGLE NUCLEOTIDE REPLACEMENT PATHWAY Genes involved in Base-free sugar-phosphate removal via the single-nucleotide replacement pathway
0.0 0.7 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.0 0.2 REACTOME PHOSPHORYLATION OF CD3 AND TCR ZETA CHAINS Genes involved in Phosphorylation of CD3 and TCR zeta chains
0.0 0.7 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.0 0.3 REACTOME CD28 DEPENDENT VAV1 PATHWAY Genes involved in CD28 dependent Vav1 pathway
0.0 0.1 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.0 0.8 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.4 REACTOME PERK REGULATED GENE EXPRESSION Genes involved in PERK regulated gene expression
0.0 0.2 REACTOME BILE SALT AND ORGANIC ANION SLC TRANSPORTERS Genes involved in Bile salt and organic anion SLC transporters
0.0 0.3 REACTOME CHONDROITIN SULFATE BIOSYNTHESIS Genes involved in Chondroitin sulfate biosynthesis
0.0 0.1 REACTOME ETHANOL OXIDATION Genes involved in Ethanol oxidation
0.0 0.3 REACTOME SIGNALING BY CONSTITUTIVELY ACTIVE EGFR Genes involved in Signaling by constitutively active EGFR
0.0 0.2 REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC Genes involved in Antigen Presentation: Folding, assembly and peptide loading of class I MHC