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avrg: GFI1 WT vs 36n/n vs KD

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Results for Foxg1

Z-value: 0.77

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Transcription factors associated with Foxg1

Gene Symbol Gene ID Gene Info
ENSMUSG00000020950.11 forkhead box G1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Foxg1mm39_v1_chr12_+_49429574_49429666-0.602.9e-01Click!

Activity profile of Foxg1 motif

Sorted Z-values of Foxg1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr13_+_34346936 0.58 ENSMUST00000124996.8
ENSMUST00000147632.3
proteasome (prosome, macropain) assembly chaperone 4
chr18_+_68433422 0.54 ENSMUST00000009679.11
ENSMUST00000131075.8
ENSMUST00000025427.14
ENSMUST00000139111.2
RNA (guanine-7-) methyltransferase
chr9_+_106048116 0.52 ENSMUST00000020490.13
WD repeat domain containing 82
chr3_-_50398027 0.41 ENSMUST00000029297.6
ENSMUST00000194462.6
solute carrier family 7 (cationic amino acid transporter, y+ system), member 11
chr15_+_79775819 0.37 ENSMUST00000177350.8
apolipoprotein B mRNA editing enzyme, catalytic polypeptide 3
chr8_+_112263632 0.36 ENSMUST00000173506.8
zinc and ring finger 1
chr5_-_121329385 0.31 ENSMUST00000054547.9
ENSMUST00000100770.9
protein tyrosine phosphatase, non-receptor type 11
chr3_-_106057077 0.24 ENSMUST00000149836.2
chitinase-like 3
chr1_-_180641099 0.23 ENSMUST00000159789.2
ENSMUST00000081026.11
H3.3 histone A
chr7_+_75498058 0.23 ENSMUST00000171155.4
ENSMUST00000092073.11
ENSMUST00000206019.2
ENSMUST00000205612.2
ENSMUST00000205887.2
kelch-like 25
chr3_+_84081411 0.22 ENSMUST00000193882.2
predicted pseudogene 6525
chr1_-_180641430 0.22 ENSMUST00000162814.8
H3.3 histone A
chr2_-_152672535 0.22 ENSMUST00000146380.2
ENSMUST00000134902.2
ENSMUST00000134357.2
ENSMUST00000109820.5
BCL2-like 1
chr4_-_108690741 0.21 ENSMUST00000102740.8
ENSMUST00000102741.8
basic transcription factor 3-like 4
chr7_+_142558783 0.20 ENSMUST00000009396.13
tetraspanin 32
chr1_-_180641159 0.20 ENSMUST00000162118.8
ENSMUST00000159685.2
ENSMUST00000161308.8
H3.3 histone A
chr2_-_154400753 0.20 ENSMUST00000109716.9
ENSMUST00000000895.13
ENSMUST00000125793.2
N-terminal EF-hand calcium binding protein 3
chr7_+_142558837 0.18 ENSMUST00000207211.2
tetraspanin 32
chr19_+_11747721 0.18 ENSMUST00000167199.3
mitochondrial ribosomal protein L16
chr6_-_72322116 0.17 ENSMUST00000070345.5
ubiquitin specific peptidase 39
chr7_+_79848138 0.16 ENSMUST00000205822.2
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
chr18_-_68433398 0.16 ENSMUST00000042852.7
family with sequence similarity 210, member A
chr5_+_145141333 0.15 ENSMUST00000085671.10
ENSMUST00000031601.8
zinc finger with KRAB and SCAN domains 5
chr9_+_54493784 0.15 ENSMUST00000167866.2
isocitrate dehydrogenase 3 (NAD+) alpha
chr15_+_79775894 0.14 ENSMUST00000177483.8
apolipoprotein B mRNA editing enzyme, catalytic polypeptide 3
chr17_+_81251997 0.14 ENSMUST00000025092.5
transmembrane protein 178
chr8_+_112263465 0.14 ENSMUST00000095176.12
zinc and ring finger 1
chr14_-_121935829 0.13 ENSMUST00000040700.9
ENSMUST00000212181.2
dedicator of cytokinesis 9
chr2_+_28403255 0.12 ENSMUST00000028170.15
ral guanine nucleotide dissociation stimulator
chr7_-_41210219 0.12 ENSMUST00000164677.2
ENSMUST00000073410.12
predicted gene 6871
chr11_-_97635484 0.12 ENSMUST00000018691.9
phosphatidylinositol-5-phosphate 4-kinase, type II, beta
chr2_-_152673032 0.11 ENSMUST00000128172.3
BCL2-like 1
chr1_+_82817170 0.10 ENSMUST00000189220.7
ENSMUST00000113444.8
ArfGAP with FG repeats 1
chr9_+_54493618 0.10 ENSMUST00000217484.2
isocitrate dehydrogenase 3 (NAD+) alpha
chr4_+_141520923 0.10 ENSMUST00000097805.11
ENSMUST00000030747.11
ENSMUST00000153094.2
caspase 9
chr11_-_119932573 0.09 ENSMUST00000103019.2
apoptosis-associated tyrosine kinase
chr9_-_60557076 0.08 ENSMUST00000053171.14
leucine rich repeat containing 49
chr8_+_112262729 0.08 ENSMUST00000172856.8
zinc and ring finger 1
chr12_-_112964279 0.07 ENSMUST00000011302.9
BRF1, RNA polymerase III transcription initiation factor 90 kDa subunit
chr1_-_79838897 0.07 ENSMUST00000190724.2
serine (or cysteine) peptidase inhibitor, clade E, member 2
chr1_-_72914036 0.07 ENSMUST00000027377.9
insulin-like growth factor binding protein 5
chr8_+_93628015 0.07 ENSMUST00000104947.5
calpain, small subunit 2
chr2_+_28403084 0.05 ENSMUST00000135803.8
ral guanine nucleotide dissociation stimulator
chr12_-_59058780 0.05 ENSMUST00000021375.12
SEC23 homolog A, COPII coat complex component
chr15_+_103148824 0.05 ENSMUST00000036004.16
ENSMUST00000087351.9
ENSMUST00000231141.2
heterogeneous nuclear ribonucleoprotein A1
chr11_+_72498029 0.04 ENSMUST00000021148.13
ENSMUST00000138247.8
ubiquitin-conjugating enzyme E2G 1
chr8_+_112263255 0.04 ENSMUST00000171182.8
ENSMUST00000168428.8
zinc and ring finger 1
chr15_+_66449385 0.04 ENSMUST00000230882.2
ENSMUST00000048188.10
ENSMUST00000230948.2
ENSMUST00000229160.2
PHD finger protein 20-like 1
chr1_-_120432477 0.03 ENSMUST00000186432.3
macrophage receptor with collagenous structure
chr3_-_94922525 0.02 ENSMUST00000128438.2
ENSMUST00000149747.2
ENSMUST00000019482.8
zinc finger protein 687
chr16_-_97306125 0.01 ENSMUST00000049721.9
ENSMUST00000231999.2
family with sequence similarity 3, member B
chr11_-_99684173 0.01 ENSMUST00000105058.2
predicted gene 11596
chr2_-_89159994 0.01 ENSMUST00000213860.2
ENSMUST00000215679.2
olfactory receptor 1232
chr1_+_180762587 0.01 ENSMUST00000037361.9
left right determination factor 1
chr2_-_162929732 0.01 ENSMUST00000094653.6
gametocyte specific factor 1-like
chr16_-_28748410 0.01 ENSMUST00000100023.3
Mab-21 domain containing 2
chr6_-_128503666 0.01 ENSMUST00000143664.2
ENSMUST00000112132.8
PZP, alpha-2-macroglobulin like
chr7_-_21053786 0.00 ENSMUST00000105199.2
vomeronasal 1 receptor 127
chr2_+_74522258 0.00 ENSMUST00000061745.5
homeobox D10
chr7_-_21496153 0.00 ENSMUST00000105196.2
vomeronasal 1 receptor 248
chr7_-_22719348 0.00 ENSMUST00000168926.2
vomeronasal 1 receptor 259
chr2_+_120331784 0.00 ENSMUST00000151342.3
calpain 3
chr13_+_21887145 0.00 ENSMUST00000077843.6
olfactory receptor 1359

Network of associatons between targets according to the STRING database.

First level regulatory network of Foxg1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.7 GO:0031509 telomeric heterochromatin assembly(GO:0031509) negative regulation of chromosome condensation(GO:1902340)
0.1 0.3 GO:2000850 negative regulation of corticosteroid hormone secretion(GO:2000847) negative regulation of glucocorticoid secretion(GO:2000850)
0.1 0.3 GO:0046898 response to cycloheximide(GO:0046898)
0.1 0.5 GO:0036265 RNA (guanine-N7)-methylation(GO:0036265)
0.0 0.4 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.0 0.6 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.4 GO:0030886 negative regulation of myeloid dendritic cell activation(GO:0030886)
0.0 0.2 GO:0006102 isocitrate metabolic process(GO:0006102)
0.0 0.5 GO:0080182 histone H3-K4 trimethylation(GO:0080182)
0.0 0.2 GO:0006032 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0 0.5 GO:0010528 regulation of transposition(GO:0010528) negative regulation of transposition(GO:0010529)
0.0 0.1 GO:0061107 seminal vesicle development(GO:0061107)
0.0 0.1 GO:0014734 skeletal muscle hypertrophy(GO:0014734)
0.0 0.2 GO:0042984 amyloid precursor protein biosynthetic process(GO:0042983) regulation of amyloid precursor protein biosynthetic process(GO:0042984)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0001740 Barr body(GO:0001740)
0.1 0.4 GO:0070442 integrin alphaIIb-beta3 complex(GO:0070442)
0.1 0.5 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 0.5 GO:0005845 mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.0 0.3 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.1 GO:0043293 apoptosome(GO:0043293)
0.0 0.2 GO:0000137 Golgi cis cisterna(GO:0000137)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.5 GO:0047844 deoxycytidine deaminase activity(GO:0047844)
0.1 0.4 GO:0000099 sulfur amino acid transmembrane transporter activity(GO:0000099)
0.0 0.2 GO:0004449 isocitrate dehydrogenase (NAD+) activity(GO:0004449)
0.0 0.2 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.0 0.5 GO:0008174 mRNA methyltransferase activity(GO:0008174)
0.0 0.1 GO:0016309 1-phosphatidylinositol-5-phosphate 4-kinase activity(GO:0016309)
0.0 0.3 GO:0004726 non-membrane spanning protein tyrosine phosphatase activity(GO:0004726)
0.0 0.3 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.5 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.1 GO:0000995 transcription factor activity, core RNA polymerase III binding(GO:0000995)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.7 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.5 REACTOME MRNA CAPPING Genes involved in mRNA Capping
0.0 0.3 REACTOME INFLAMMASOMES Genes involved in Inflammasomes