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avrg: GFI1 WT vs 36n/n vs KD

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Results for GUAGUGU

Z-value: 0.75

Motif logo

miRNA associated with seed GUAGUGU

NamemiRBASE accession
MIMAT0000155

Activity profile of GUAGUGU motif

Sorted Z-values of GUAGUGU motif

Promoter Log-likelihood Transcript Gene Gene Info
chr17_-_32074754 0.65 ENSMUST00000024839.6
salt inducible kinase 1
chr8_-_123768759 0.42 ENSMUST00000098334.13
ankyrin repeat domain 11
chr9_-_123680927 0.40 ENSMUST00000184082.3
ENSMUST00000167595.9
FYVE and coiled-coil domain containing 1
chr9_-_110237276 0.32 ENSMUST00000040021.12
protein tyrosine phosphatase, non-receptor type 23
chr9_-_43017249 0.31 ENSMUST00000165665.9
Rho guanine nucleotide exchange factor (GEF) 12
chr4_+_150366028 0.31 ENSMUST00000105682.9
arginine glutamic acid dipeptide (RE) repeats
chr7_-_63588610 0.30 ENSMUST00000063694.10
Kruppel-like factor 13
chr2_-_12306722 0.30 ENSMUST00000028106.11
integrin alpha 8
chr18_+_34354031 0.28 ENSMUST00000115781.10
ENSMUST00000079362.13
APC, WNT signaling pathway regulator
chr1_-_96799832 0.25 ENSMUST00000071985.6
solute carrier organic anion transporter family, member 4C1
chr3_+_88857929 0.22 ENSMUST00000186583.7
ASH1 like histone lysine methyltransferase
chr14_-_4198510 0.21 ENSMUST00000133460.2
ENSMUST00000132374.9
NFKB inhibitor interacting Ras-like protein 1
chr5_+_123532819 0.19 ENSMUST00000111596.8
ENSMUST00000068237.12
MLX interacting protein
chr6_-_24664959 0.18 ENSMUST00000041737.8
ENSMUST00000031695.15
WASP like actin nucleation promoting factor
chr17_+_36227433 0.18 ENSMUST00000087211.9
protein phosphatase 1, regulatory subunit 10
chr14_-_25769457 0.17 ENSMUST00000069180.8
zinc finger, CCHC domain containing 24
chr6_-_83418656 0.17 ENSMUST00000089622.11
tet methylcytosine dioxygenase 3
chr5_-_106844685 0.16 ENSMUST00000127434.8
ENSMUST00000112696.8
ENSMUST00000112698.8
zinc finger protein 644
chr5_+_103902020 0.16 ENSMUST00000054979.10
AF4/FMR2 family, member 1
chr15_+_12117899 0.16 ENSMUST00000122941.8
zinc finger RNA binding protein
chr8_-_110464345 0.16 ENSMUST00000212605.2
ENSMUST00000093162.4
ENSMUST00000212726.2
ataxin 1-like
chr5_-_62923463 0.15 ENSMUST00000076623.8
ENSMUST00000159470.3
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 2
chr15_-_102165884 0.15 ENSMUST00000043172.15
retinoic acid receptor, gamma
chr11_+_68393845 0.15 ENSMUST00000102613.8
ENSMUST00000060441.7
phosphoinositide-3-kinase regulatory subunit 5
chr15_-_9529898 0.15 ENSMUST00000228782.2
ENSMUST00000003981.6
interleukin 7 receptor
chr7_-_16348862 0.14 ENSMUST00000171937.2
ENSMUST00000075845.11
Rho GTPase activating protein 35
chr16_+_42727926 0.14 ENSMUST00000151244.8
ENSMUST00000114694.9
zinc finger and BTB domain containing 20
chr12_-_91556761 0.13 ENSMUST00000021345.14
general transcription factor II A, 1
chr6_+_128339882 0.13 ENSMUST00000073316.13
forkhead box M1
chr9_-_101128976 0.13 ENSMUST00000075941.12
protein phosphatase 2, regulatory subunit B'', alpha
chr5_+_108609087 0.13 ENSMUST00000112597.8
ENSMUST00000046975.12
polycomb group ring finger 3
chr7_-_117842787 0.13 ENSMUST00000032891.15
SMG1 homolog, phosphatidylinositol 3-kinase-related kinase (C. elegans)
chr6_+_136495784 0.12 ENSMUST00000032335.13
ENSMUST00000185724.7
activating transcription factor 7 interacting protein
chr6_-_39354570 0.12 ENSMUST00000200771.4
ENSMUST00000202204.4
ENSMUST00000202952.2
ENSMUST00000202400.4
ENSMUST00000200969.4
ENSMUST00000202749.4
ENSMUST00000090243.8
solute carrier family 37 (glycerol-3-phosphate transporter), member 3
chr4_-_135749032 0.12 ENSMUST00000030427.6
elongin A
chr10_-_127124718 0.12 ENSMUST00000156208.2
ENSMUST00000026476.13
methyl-CpG binding domain protein 6
chr8_+_71207326 0.12 ENSMUST00000110093.9
ENSMUST00000143118.3
ENSMUST00000034301.12
ENSMUST00000110090.8
RAB3A, member RAS oncogene family
chr2_-_73722874 0.11 ENSMUST00000136958.8
ENSMUST00000112010.9
ENSMUST00000128531.8
ENSMUST00000112017.8
activating transcription factor 2
chr3_-_115800989 0.10 ENSMUST00000067485.4
solute carrier family 30 (zinc transporter), member 7
chr10_-_120312374 0.10 ENSMUST00000072777.14
ENSMUST00000159699.2
high mobility group AT-hook 2
chr12_+_16944896 0.10 ENSMUST00000020904.8
Rho-associated coiled-coil containing protein kinase 2
chr13_+_81031512 0.10 ENSMUST00000099356.10
arrestin domain containing 3
chr1_+_87683592 0.09 ENSMUST00000144047.8
ENSMUST00000027512.13
ENSMUST00000113186.8
ENSMUST00000113190.3
autophagy related 16-like 1 (S. cerevisiae)
chr13_+_113931038 0.09 ENSMUST00000091201.7
ADP-ribosylation factor-like 15
chr15_+_10177709 0.09 ENSMUST00000124470.8
prolactin receptor
chr19_+_41471067 0.09 ENSMUST00000067795.13
ligand dependent nuclear receptor corepressor
chr15_-_82108531 0.09 ENSMUST00000109535.3
ENSMUST00000089161.10
tumor necrosis factor receptor superfamily, member 13c
chr10_+_20188207 0.09 ENSMUST00000092678.10
ENSMUST00000043881.12
BCL2-associated transcription factor 1
chr1_+_127701901 0.09 ENSMUST00000112570.2
ENSMUST00000027587.15
cyclin T2
chr15_-_77726333 0.09 ENSMUST00000016771.13
myosin, heavy polypeptide 9, non-muscle
chr14_-_21102487 0.09 ENSMUST00000154460.8
ENSMUST00000130291.8
adaptor-related protein complex 3, mu 1 subunit
chr2_-_38955452 0.08 ENSMUST00000112850.9
golgi autoantigen, golgin subfamily a, 1
chr5_+_138083345 0.08 ENSMUST00000019660.11
ENSMUST00000066617.12
ENSMUST00000110963.8
zinc finger with KRAB and SCAN domains 1
chr7_+_5083212 0.08 ENSMUST00000098845.10
ENSMUST00000146317.8
ENSMUST00000153169.2
ENSMUST00000045277.7
epsin 1
chrX_-_107877909 0.08 ENSMUST00000101283.4
ENSMUST00000150434.8
bromodomain and WD repeat domain containing 3
chr5_-_76452365 0.08 ENSMUST00000075159.5
circadian locomotor output cycles kaput
chr11_+_80319424 0.08 ENSMUST00000173938.8
ENSMUST00000017572.14
proteasome (prosome, macropain) 26S subunit, non-ATPase, 11
chr11_+_68582731 0.08 ENSMUST00000102611.10
myosin, heavy polypeptide 10, non-muscle
chr10_+_7556948 0.08 ENSMUST00000165952.9
large tumor suppressor
chr13_-_3661064 0.08 ENSMUST00000096069.5
transcription activation suppressor family member 2
chr9_-_50920236 0.07 ENSMUST00000176824.8
ENSMUST00000176663.8
ENSMUST00000041375.11
salt inducible kinase 2
chr2_-_45003270 0.07 ENSMUST00000202935.4
ENSMUST00000068415.11
ENSMUST00000127520.8
zinc finger E-box binding homeobox 2
chr2_-_130681978 0.07 ENSMUST00000044766.15
ENSMUST00000138990.2
ENSMUST00000120316.8
ENSMUST00000110243.8
RIKEN cDNA 4930402H24 gene
chr18_+_42408418 0.07 ENSMUST00000091920.6
ENSMUST00000046972.14
ENSMUST00000236240.2
RNA binding motif protein 27
chr2_+_113271409 0.07 ENSMUST00000081349.9
formin 1
chr19_+_16110176 0.07 ENSMUST00000025541.6
guanine nucleotide binding protein, alpha q polypeptide
chr17_+_83658354 0.07 ENSMUST00000096766.12
ENSMUST00000049503.10
ENSMUST00000112363.10
ENSMUST00000234460.2
echinoderm microtubule associated protein like 4
chr10_+_69932930 0.06 ENSMUST00000147545.8
coiled-coil domain containing 6
chr17_+_28128307 0.06 ENSMUST00000233525.2
ENSMUST00000025058.15
ENSMUST00000233866.2
ankyrin repeat and SAM domain containing 1
chr8_+_26092252 0.06 ENSMUST00000136107.9
ENSMUST00000146919.8
ENSMUST00000139966.8
ENSMUST00000142395.8
ENSMUST00000143445.2
nuclear receptor binding SET domain protein 3
chr2_+_6327431 0.06 ENSMUST00000114937.8
USP6 N-terminal like
chrX_-_47297436 0.05 ENSMUST00000037960.11
zinc finger, DHHC domain containing 9
chr7_+_44667377 0.05 ENSMUST00000044111.10
related RAS viral (r-ras) oncogene
chr4_-_132611820 0.05 ENSMUST00000030698.5
syntaxin 12
chr18_+_5591864 0.05 ENSMUST00000025081.13
ENSMUST00000159390.8
zinc finger E-box binding homeobox 1
chr16_+_10306075 0.05 ENSMUST00000023147.8
class II transactivator
chr11_+_75570085 0.05 ENSMUST00000017920.14
ENSMUST00000108426.8
ENSMUST00000108425.8
ENSMUST00000093115.4
v-crk avian sarcoma virus CT10 oncogene homolog
chr1_-_186438177 0.05 ENSMUST00000045288.14
transforming growth factor, beta 2
chr4_+_131649001 0.05 ENSMUST00000094666.4
transmembrane protein 200B
chr7_+_89779564 0.05 ENSMUST00000208742.2
ENSMUST00000049537.9
phosphatidylinositol binding clathrin assembly protein
chr2_+_113158053 0.05 ENSMUST00000099576.9
formin 1
chr15_+_6737853 0.04 ENSMUST00000061656.8
RPTOR independent companion of MTOR, complex 2
chrX_-_73067514 0.04 ENSMUST00000033769.15
ENSMUST00000114352.8
ENSMUST00000068286.12
ENSMUST00000114360.10
ENSMUST00000114354.10
interleukin-1 receptor-associated kinase 1
chr17_-_84495364 0.04 ENSMUST00000060366.7
zinc finger protein 36, C3H type-like 2
chr13_+_112600604 0.04 ENSMUST00000183663.8
ENSMUST00000184311.8
ENSMUST00000183886.8
interleukin 6 signal transducer
chr7_+_138968988 0.04 ENSMUST00000106098.8
ENSMUST00000026550.14
inositol polyphosphate-5-phosphatase A
chr3_-_144426076 0.04 ENSMUST00000198254.5
ENSMUST00000163279.6
SH3-domain GRB2-like B1 (endophilin)
chr1_+_180158035 0.04 ENSMUST00000070181.7
inositol 1,4,5-trisphosphate 3-kinase B
chr9_-_22300409 0.04 ENSMUST00000040912.9
anillin, actin binding protein
chr7_-_144024451 0.04 ENSMUST00000033407.13
cortactin
chrX_+_18028814 0.03 ENSMUST00000044484.13
ENSMUST00000052368.9
lysine (K)-specific demethylase 6A
chr14_+_30547541 0.03 ENSMUST00000006701.8
STIM activating enhancer
chr15_-_73056713 0.03 ENSMUST00000044113.12
argonaute RISC catalytic subunit 2
chr1_+_139349912 0.03 ENSMUST00000200243.5
ENSMUST00000039867.10
zinc finger and BTB domain containing 41
chr11_-_95200382 0.03 ENSMUST00000092766.12
ENSMUST00000072621.12
K(lysine) acetyltransferase 7
chr2_-_153371861 0.03 ENSMUST00000035346.14
nucleolar protein 4-like
chr17_-_47998953 0.03 ENSMUST00000113301.2
ENSMUST00000113302.10
translocase of outer mitochondrial membrane 6
chr12_-_51738666 0.03 ENSMUST00000013130.15
ENSMUST00000169503.4
striatin, calmodulin binding protein 3
chr1_-_151304191 0.03 ENSMUST00000064771.12
SWT1 RNA endoribonuclease homolog (S. cerevisiae)
chr4_+_102112189 0.02 ENSMUST00000106908.9
phosphodiesterase 4B, cAMP specific
chr2_-_169973076 0.02 ENSMUST00000063710.13
zinc finger protein 217
chr7_-_66339319 0.02 ENSMUST00000124899.8
ankyrin repeat and SOCS box-containing 7
chr16_+_87495792 0.02 ENSMUST00000026703.6
BTB and CNC homology 1, basic leucine zipper transcription factor 1
chr16_-_56537808 0.02 ENSMUST00000065515.14
Trk-fused gene
chr9_-_44792575 0.02 ENSMUST00000114689.8
ENSMUST00000002095.11
ENSMUST00000128768.3
lysine (K)-specific methyltransferase 2A
chr1_+_55170390 0.01 ENSMUST00000159311.8
ENSMUST00000162364.8
MOB family member 4, phocein
chr11_-_88609048 0.01 ENSMUST00000107909.8
musashi RNA-binding protein 2
chr10_-_37014859 0.01 ENSMUST00000092584.6
myristoylated alanine rich protein kinase C substrate
chr2_-_166838018 0.01 ENSMUST00000049412.12
staufen double-stranded RNA binding protein 1
chr3_+_52175757 0.01 ENSMUST00000053764.7
forkhead box O1
chr4_+_116578117 0.01 ENSMUST00000045542.13
ENSMUST00000106459.8
testis-specific kinase 2
chr4_-_129534853 0.01 ENSMUST00000046425.16
ENSMUST00000133803.8
taxilin alpha
chr18_-_6241470 0.01 ENSMUST00000163210.2
ENSMUST00000025083.14
kinesin family member 5B
chr10_-_89279751 0.01 ENSMUST00000219351.2
ENSMUST00000220128.2
ENSMUST00000099374.9
ENSMUST00000105298.3
growth arrest-specific 2 like 3
chr7_+_44498640 0.01 ENSMUST00000054343.15
ENSMUST00000142880.3
AKT1 substrate 1 (proline-rich)
chrX_+_5959507 0.01 ENSMUST00000103007.4
nudix (nucleoside diphosphate linked moiety X)-type motif 11
chr18_-_77801624 0.01 ENSMUST00000074653.6
RIKEN cDNA 8030462N17 gene
chr10_-_7831979 0.01 ENSMUST00000146444.8
TGF-beta activated kinase 1/MAP3K7 binding protein 2
chr3_+_9315662 0.01 ENSMUST00000155203.2
zinc finger and BTB domain containing 10
chr4_-_148711453 0.01 ENSMUST00000165113.8
ENSMUST00000172073.8
ENSMUST00000105702.9
ENSMUST00000084125.10
TAR DNA binding protein
chr15_-_94487751 0.01 ENSMUST00000023087.13
ENSMUST00000152590.2
twinfilin actin binding protein 1
chr1_-_46893206 0.01 ENSMUST00000027131.6
solute carrier family 39 (zinc transporter), member 10
chrX_-_143471176 0.01 ENSMUST00000040184.4
transient receptor potential cation channel, subfamily C, member 5
chr7_+_109617456 0.01 ENSMUST00000084731.5
importin 7
chr14_-_8457069 0.01 ENSMUST00000022257.4
ataxin 7
chr3_+_144998233 0.00 ENSMUST00000029848.5
ENSMUST00000139001.2
collagen, type XXIV, alpha 1
chr5_-_143513732 0.00 ENSMUST00000100489.4
ENSMUST00000080537.14
Rac family small GTPase 1
chr2_-_52632178 0.00 ENSMUST00000102759.8
ENSMUST00000127316.8
signal transducing adaptor molecule (SH3 domain and ITAM motif) 2
chr9_-_90152759 0.00 ENSMUST00000041767.14
ENSMUST00000128874.3
TBC1 domain family, member 2B
chr13_+_38010203 0.00 ENSMUST00000128570.9
ras responsive element binding protein 1
chr2_-_103133524 0.00 ENSMUST00000090475.10
ets homologous factor

Network of associatons between targets according to the STRING database.

First level regulatory network of GUAGUGU

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.3 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.1 0.6 GO:0032792 negative regulation of CREB transcription factor activity(GO:0032792)
0.1 0.3 GO:0021691 cerebellar Purkinje cell layer maturation(GO:0021691)
0.1 0.2 GO:1903699 tarsal gland development(GO:1903699)
0.1 0.4 GO:0072383 plus-end-directed vesicle transport along microtubule(GO:0072383) plus-end-directed organelle transport along microtubule(GO:0072386)
0.1 0.3 GO:2000721 positive regulation of transcription from RNA polymerase II promoter involved in smooth muscle cell differentiation(GO:2000721)
0.0 0.3 GO:2000211 regulation of glutamate metabolic process(GO:2000211)
0.0 0.2 GO:0044727 DNA demethylation of male pronucleus(GO:0044727)
0.0 0.1 GO:0038161 prolactin signaling pathway(GO:0038161)
0.0 0.2 GO:0003430 growth plate cartilage chondrocyte growth(GO:0003430)
0.0 0.1 GO:0019085 early viral transcription(GO:0019085)
0.0 0.1 GO:0032915 positive regulation of transforming growth factor beta2 production(GO:0032915)
0.0 0.2 GO:0030950 establishment or maintenance of actin cytoskeleton polarity(GO:0030950)
0.0 0.1 GO:0001915 negative regulation of T cell mediated cytotoxicity(GO:0001915)
0.0 0.1 GO:0090325 regulation of locomotion involved in locomotory behavior(GO:0090325) negative regulation of locomotion involved in locomotory behavior(GO:0090327)
0.0 0.1 GO:0061739 protein lipidation involved in autophagosome assembly(GO:0061739)
0.0 0.1 GO:0099558 maintenance of synapse structure(GO:0099558)
0.0 0.2 GO:1902035 positive regulation of hematopoietic stem cell proliferation(GO:1902035)
0.0 0.1 GO:1900756 protein processing in phagocytic vesicle(GO:1900756) regulation of protein processing in phagocytic vesicle(GO:1903921) positive regulation of protein processing in phagocytic vesicle(GO:1903923)
0.0 0.2 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.1 GO:0070650 actin filament bundle distribution(GO:0070650)
0.0 0.1 GO:0001827 inner cell mass cell fate commitment(GO:0001827)
0.0 0.1 GO:0035526 retrograde transport, plasma membrane to Golgi(GO:0035526)
0.0 0.1 GO:0031296 B cell costimulation(GO:0031296)
0.0 0.1 GO:0090245 axis elongation involved in somitogenesis(GO:0090245)
0.0 0.1 GO:1990859 cellular response to endothelin(GO:1990859)
0.0 0.1 GO:0072092 ureteric bud invasion(GO:0072092)
0.0 0.1 GO:1903347 negative regulation of bicellular tight junction assembly(GO:1903347)
0.0 0.0 GO:0051795 endocardial cushion fusion(GO:0003274) positive regulation of catagen(GO:0051795) positive regulation of activation-induced cell death of T cells(GO:0070237) negative regulation of epithelial to mesenchymal transition involved in endocardial cushion formation(GO:1905006)
0.0 0.3 GO:0045647 negative regulation of erythrocyte differentiation(GO:0045647)
0.0 0.0 GO:0070104 negative regulation of interleukin-6-mediated signaling pathway(GO:0070104)
0.0 0.0 GO:1903778 protein localization to vacuolar membrane(GO:1903778)
0.0 0.0 GO:1904172 positive regulation of bleb assembly(GO:1904172)
0.0 0.1 GO:0045634 regulation of melanocyte differentiation(GO:0045634)
0.0 0.0 GO:0072720 response to sorbitol(GO:0072708) response to dithiothreitol(GO:0072720)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.0 0.1 GO:0005944 phosphatidylinositol 3-kinase complex, class IB(GO:0005944)
0.0 0.2 GO:0097513 myosin II filament(GO:0097513)
0.0 0.3 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.1 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.1 GO:0070449 elongin complex(GO:0070449)
0.0 0.2 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.0 0.2 GO:0030478 actin cap(GO:0030478)
0.0 0.1 GO:0098890 extrinsic component of postsynaptic membrane(GO:0098890)
0.0 0.2 GO:0001940 male pronucleus(GO:0001940)
0.0 0.0 GO:0005900 oncostatin-M receptor complex(GO:0005900)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 GO:0008140 cAMP response element binding protein binding(GO:0008140)
0.0 0.2 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.1 GO:0031699 beta-3 adrenergic receptor binding(GO:0031699)
0.0 0.1 GO:0031826 type 2A serotonin receptor binding(GO:0031826)
0.0 0.2 GO:0070579 methylcytosine dioxygenase activity(GO:0070579)
0.0 0.1 GO:0046935 1-phosphatidylinositol-3-kinase regulator activity(GO:0046935)
0.0 0.0 GO:0019981 interleukin-6 receptor activity(GO:0004915) interleukin-6 binding(GO:0019981)
0.0 0.3 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.0 GO:0098808 mRNA cap binding(GO:0098808)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 ST PAC1 RECEPTOR PATHWAY PAC1 Receptor Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME TRANSPORT OF ORGANIC ANIONS Genes involved in Transport of organic anions
0.0 0.8 REACTOME SEMA4D IN SEMAPHORIN SIGNALING Genes involved in Sema4D in semaphorin signaling
0.0 0.3 REACTOME CTNNB1 PHOSPHORYLATION CASCADE Genes involved in Beta-catenin phosphorylation cascade
0.0 0.1 REACTOME ACETYLCHOLINE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Acetylcholine Neurotransmitter Release Cycle