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avrg: GFI1 WT vs 36n/n vs KD

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Results for Gbx1_Nobox_Alx3

Z-value: 1.58

Motif logo

Transcription factors associated with Gbx1_Nobox_Alx3

Gene Symbol Gene ID Gene Info
ENSMUSG00000067724.6 gastrulation brain homeobox 1
ENSMUSG00000029736.16 NOBOX oogenesis homeobox
ENSMUSG00000014603.4 aristaless-like homeobox 3

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Alx3mm39_v1_chr3_+_107502347_107502479-0.781.2e-01Click!
Noboxmm39_v1_chr6_-_43286488_43286488-0.553.4e-01Click!
Gbx1mm39_v1_chr5_-_24732200_24732200-0.148.2e-01Click!

Activity profile of Gbx1_Nobox_Alx3 motif

Sorted Z-values of Gbx1_Nobox_Alx3 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr18_-_43610829 1.83 ENSMUST00000057110.11
eukaryotic translation initiation factor 3, subunit J2
chrX_+_55500170 1.44 ENSMUST00000039374.9
ENSMUST00000101553.9
ENSMUST00000186445.7
integrator complex subunit 6 like
chr8_+_107757847 1.41 ENSMUST00000034388.10
vacuolar protein sorting 4A
chr19_-_24178000 1.31 ENSMUST00000233658.3
tight junction protein 2
chr5_-_65855511 1.17 ENSMUST00000201948.4
PDS5 cohesin associated factor A
chr9_-_96513529 1.06 ENSMUST00000034984.8
RAS p21 protein activator 2
chr12_-_73093953 1.06 ENSMUST00000050029.8
sine oculis-related homeobox 1
chr10_+_39488930 1.03 ENSMUST00000019987.7
TRAF3 interacting protein 2
chr3_-_130524024 1.02 ENSMUST00000079085.11
ribosomal protein L34
chr14_+_79753055 0.99 ENSMUST00000110835.3
ENSMUST00000227192.2
E74-like factor 1
chr9_+_113641615 0.97 ENSMUST00000111838.10
ENSMUST00000166734.10
ENSMUST00000214522.2
ENSMUST00000163895.3
CLIP associating protein 2
chr2_+_36120438 0.95 ENSMUST00000062069.6
prostaglandin-endoperoxide synthase 1
chr17_+_46471950 0.91 ENSMUST00000024748.14
ENSMUST00000172170.8
GTP binding protein 2
chr14_+_32043944 0.90 ENSMUST00000022480.8
ENSMUST00000228529.2
oxoglutarate dehydrogenase-like
chr7_-_45480200 0.84 ENSMUST00000107723.9
ENSMUST00000131384.3
glutamate-rich WD repeat containing 1
chr3_+_159545309 0.82 ENSMUST00000068952.10
ENSMUST00000198878.2
wntless WNT ligand secretion mediator
chr10_+_128173603 0.77 ENSMUST00000005826.9
citrate synthase
chr2_-_152857239 0.74 ENSMUST00000028972.9
p53 and DNA damage regulated 1
chr5_-_137530214 0.74 ENSMUST00000140139.2
guanine nucleotide binding protein (G protein), beta 2
chr11_+_60428788 0.73 ENSMUST00000044250.4
alkB homolog 5, RNA demethylase
chr1_-_171854818 0.70 ENSMUST00000138714.2
ENSMUST00000027837.13
ENSMUST00000111264.8
VANGL planar cell polarity 2
chr11_-_107228382 0.67 ENSMUST00000040380.13
phosphatidylinositol transfer protein, cytoplasmic 1
chr4_-_43710231 0.64 ENSMUST00000217544.2
ENSMUST00000107862.3
olfactory receptor 71
chr12_+_111780604 0.64 ENSMUST00000021714.9
ENSMUST00000223211.2
ENSMUST00000222843.2
ENSMUST00000221375.2
zinc finger, FYVE domain containing 21
chr3_+_68479578 0.63 ENSMUST00000170788.9
schwannomin interacting protein 1
chr2_+_71219561 0.62 ENSMUST00000028408.3
histone aminotransferase 1
chr11_+_23256909 0.61 ENSMUST00000137823.8
ubiquitin specific peptidase 34
chr16_+_35861554 0.61 ENSMUST00000042203.10
WD repeat domain 5B
chrX_+_149330371 0.60 ENSMUST00000066337.13
ENSMUST00000112715.2
aminolevulinic acid synthase 2, erythroid
chr19_-_46033353 0.60 ENSMUST00000026252.14
ENSMUST00000156585.9
ENSMUST00000185355.7
ENSMUST00000152946.8
LIM domain binding 1
chr5_+_115373895 0.60 ENSMUST00000081497.13
processing of precursor 5, ribonuclease P/MRP family (S. cerevisiae)
chr18_+_66591604 0.60 ENSMUST00000025399.9
ENSMUST00000237161.2
ENSMUST00000236933.2
phorbol-12-myristate-13-acetate-induced protein 1
chr11_+_102175985 0.58 ENSMUST00000156326.2
transmembrane and ubiquitin-like domain containing 2
chr11_+_23256883 0.58 ENSMUST00000180046.8
ubiquitin specific peptidase 34
chr6_-_41752111 0.57 ENSMUST00000214976.3
olfactory receptor 459
chr16_-_35891739 0.56 ENSMUST00000231351.2
ENSMUST00000004057.9
family with sequence similarity 162, member A
chr5_-_137529465 0.54 ENSMUST00000150063.9
guanine nucleotide binding protein (G protein), beta 2
chr6_+_29853745 0.53 ENSMUST00000064872.13
ENSMUST00000152581.8
ENSMUST00000176265.8
ENSMUST00000154079.8
S-adenosylhomocysteine hydrolase-like 2
chr6_+_83142902 0.53 ENSMUST00000077407.12
ENSMUST00000113913.8
ENSMUST00000130212.8
dynactin 1
chr10_+_127257077 0.52 ENSMUST00000168780.8
R3H domain containing 2
chr10_+_99099084 0.51 ENSMUST00000020118.5
ENSMUST00000220291.2
dual specificity phosphatase 6
chr17_+_35481702 0.50 ENSMUST00000172785.8
histocompatibility 2, D region locus 1
chr12_-_55061117 0.50 ENSMUST00000172875.8
bromodomain adjacent to zinc finger domain 1A
chr19_+_45433899 0.50 ENSMUST00000224478.2
beta-transducin repeat containing protein
chr2_-_86109346 0.49 ENSMUST00000217294.2
ENSMUST00000217245.2
ENSMUST00000216432.2
olfactory receptor 1051
chr7_+_101546059 0.49 ENSMUST00000143835.8
anaphase promoting complex C subunit 15
chr2_+_132689640 0.48 ENSMUST00000124836.8
ENSMUST00000154160.2
cardiolipin synthase 1
chr8_-_85389470 0.48 ENSMUST00000060427.6
immediate early response 2
chr1_+_40554513 0.48 ENSMUST00000027237.12
interleukin 18 receptor accessory protein
chr15_-_34356567 0.47 ENSMUST00000179647.2
RIKEN cDNA 9430069I07 gene
chr11_+_94218810 0.45 ENSMUST00000107818.9
ENSMUST00000051221.13
ankyrin repeat domain 40
chr9_-_105398346 0.44 ENSMUST00000176770.8
ENSMUST00000085133.13
ATPase, Ca++-sequestering
chr2_+_22959452 0.43 ENSMUST00000155602.4
acyl-Coenzyme A binding domain containing 5
chr3_+_41519289 0.41 ENSMUST00000168086.7
jade family PHD finger 1
chr7_-_98790275 0.41 ENSMUST00000037968.10
UV radiation resistance associated gene
chr16_-_92196954 0.41 ENSMUST00000023672.10
regulator of calcineurin 1
chr2_+_59442378 0.41 ENSMUST00000112568.8
ENSMUST00000037526.11
tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1
chr4_+_150322151 0.40 ENSMUST00000141931.2
enolase 1, alpha non-neuron
chr19_-_12018681 0.39 ENSMUST00000214472.2
olfactory receptor 1423
chr16_+_22676589 0.39 ENSMUST00000004574.14
ENSMUST00000178320.2
ENSMUST00000166487.10
DnaJ heat shock protein family (Hsp40) member B11
chr11_+_31823096 0.39 ENSMUST00000155278.2
cytoplasmic polyadenylation element binding protein 4
chr13_-_43634695 0.38 ENSMUST00000144326.4
RAN binding protein 9
chr3_+_32490300 0.38 ENSMUST00000029201.14
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha
chr5_+_88731366 0.37 ENSMUST00000199312.5
RUN and FYVE domain containing 3
chr18_+_24737009 0.37 ENSMUST00000234266.2
ENSMUST00000025120.8
elongator acetyltransferase complex subunit 2
chr14_+_19801333 0.36 ENSMUST00000022340.5
nidogen 2
chr3_-_19319155 0.36 ENSMUST00000091314.11
phosphodiesterase 7A
chr2_-_151586063 0.36 ENSMUST00000109869.2
proteasome (prosome, macropain) inhibitor subunit 1
chr4_-_136329953 0.36 ENSMUST00000105847.8
ENSMUST00000116273.9
lysine (K)-specific demethylase 1A
chr13_-_55169000 0.36 ENSMUST00000153665.8
hexokinase 3
chr5_-_138185438 0.35 ENSMUST00000110937.8
ENSMUST00000139276.2
ENSMUST00000048698.14
ENSMUST00000123415.8
TATA-box binding protein associated factor 6
chr11_-_20282684 0.35 ENSMUST00000004634.7
ENSMUST00000109594.8
solute carrier family 1 (glutamate/neutral amino acid transporter), member 4
chr5_-_138169253 0.34 ENSMUST00000139983.8
minichromosome maintenance complex component 7
chr18_+_56565188 0.34 ENSMUST00000070166.6
GRAM domain containing 3
chr10_-_25076008 0.34 ENSMUST00000100012.3
A kinase (PRKA) anchor protein 7
chr6_+_86342622 0.34 ENSMUST00000071492.9
family with sequence similarity 136, member A
chr15_+_41694317 0.34 ENSMUST00000166917.3
ENSMUST00000230127.2
ENSMUST00000230131.2
oxidation resistance 1
chr7_+_101545547 0.33 ENSMUST00000035395.14
ENSMUST00000106973.8
ENSMUST00000144207.9
anaphase promoting complex C subunit 15
chr18_+_23885390 0.33 ENSMUST00000170802.8
ENSMUST00000155708.8
ENSMUST00000118826.9
microtubule-associated protein, RP/EB family, member 2
chr14_+_32507920 0.32 ENSMUST00000039191.8
ENSMUST00000227060.2
ENSMUST00000228481.2
transmembrane protein 273
chr6_+_125529911 0.32 ENSMUST00000112254.8
ENSMUST00000112253.6
Von Willebrand factor
chrX_+_41241049 0.32 ENSMUST00000128799.3
stromal antigen 2
chr2_-_84481058 0.32 ENSMUST00000111670.9
ENSMUST00000111697.9
ENSMUST00000111696.8
ENSMUST00000111678.8
ENSMUST00000111690.8
ENSMUST00000111695.8
ENSMUST00000111677.8
ENSMUST00000111698.8
ENSMUST00000099941.9
ENSMUST00000111676.8
ENSMUST00000111694.8
ENSMUST00000111675.8
ENSMUST00000111689.8
ENSMUST00000111687.8
ENSMUST00000111692.8
ENSMUST00000111685.8
ENSMUST00000111686.8
ENSMUST00000111688.8
ENSMUST00000111693.8
ENSMUST00000111684.8
catenin (cadherin associated protein), delta 1
chr2_+_173579285 0.32 ENSMUST00000067530.6
vesicle-associated membrane protein, associated protein B and C
chr5_-_138169509 0.32 ENSMUST00000153867.8
minichromosome maintenance complex component 7
chr11_-_87249837 0.31 ENSMUST00000055438.5
protein phosphatase 1E (PP2C domain containing)
chr7_-_100232276 0.31 ENSMUST00000152876.3
ENSMUST00000150042.8
ENSMUST00000132888.9
mitochondrial ribosomal protein L48
chr14_-_50390356 0.31 ENSMUST00000215451.2
ENSMUST00000213163.2
ENSMUST00000215327.2
olfactory receptor 729
chr3_+_106020545 0.30 ENSMUST00000079132.12
ENSMUST00000139086.2
chitinase, acidic 1
chr15_+_21111428 0.30 ENSMUST00000075132.8
cadherin 12
chr4_+_98812047 0.30 ENSMUST00000030289.9
ubiquitin specific peptidase 1
chr12_+_72488625 0.29 ENSMUST00000161284.3
ENSMUST00000162159.8
leucine rich repeat containing 9
chr2_+_20742115 0.29 ENSMUST00000114606.8
ENSMUST00000114608.3
enhancer trap locus 4
chr19_-_15901919 0.29 ENSMUST00000162053.8
phosphoserine aminotransferase 1
chr11_+_29668563 0.28 ENSMUST00000060992.6
reticulon 4
chr6_-_129449739 0.28 ENSMUST00000112076.9
ENSMUST00000184581.3
C-type lectin domain family 7, member a
chr7_-_10488291 0.28 ENSMUST00000226874.2
ENSMUST00000227003.2
ENSMUST00000228561.2
ENSMUST00000228248.2
ENSMUST00000228526.2
ENSMUST00000228098.2
ENSMUST00000227940.2
ENSMUST00000228374.2
ENSMUST00000227702.2
vomeronasal 1 receptor 71
chr18_-_24736848 0.28 ENSMUST00000070726.10
solute carrier family 39 (metal ion transporter), member 6
chr11_-_97944239 0.27 ENSMUST00000017544.9
SH3 and cysteine rich domain 2
chr5_+_35156389 0.27 ENSMUST00000114281.8
ENSMUST00000114280.8
regulator of G-protein signaling 12
chr4_+_122730027 0.27 ENSMUST00000030412.11
ENSMUST00000121870.8
ENSMUST00000097902.5
palmitoyl-protein thioesterase 1
chr18_+_36414122 0.27 ENSMUST00000051301.6
purine rich element binding protein A
chr2_+_57887896 0.26 ENSMUST00000112616.8
ENSMUST00000166729.2
polypeptide N-acetylgalactosaminyltransferase 5
chr15_+_25774070 0.26 ENSMUST00000125667.3
myosin X
chr15_-_79658608 0.26 ENSMUST00000229644.2
ENSMUST00000023055.8
dynein, axonemal, light chain 4
chr6_-_137548004 0.26 ENSMUST00000100841.9
epidermal growth factor receptor pathway substrate 8
chrM_+_7758 0.26 ENSMUST00000082407.1
mitochondrially encoded ATP synthase 8
chr17_-_84154173 0.26 ENSMUST00000000687.9
3-hydroxyanthranilate 3,4-dioxygenase
chr2_+_26899935 0.25 ENSMUST00000114005.9
ENSMUST00000114004.8
ENSMUST00000114006.8
ENSMUST00000114007.8
ENSMUST00000133807.2
calcium channel flower domain containing 1
chr10_-_129107354 0.25 ENSMUST00000204573.3
olfactory receptor 777
chr2_-_119985078 0.24 ENSMUST00000028755.8
EH-domain containing 4
chr3_+_96552895 0.24 ENSMUST00000119365.8
ENSMUST00000029744.6
integrin, alpha 10
chr6_+_57679455 0.24 ENSMUST00000072954.8
LanC (bacterial lantibiotic synthetase component C)-like 2
chr4_+_140428777 0.24 ENSMUST00000138808.8
ENSMUST00000038893.6
regulator of chromosome condensation 2
chr8_-_58106057 0.24 ENSMUST00000034021.12
polypeptide N-acetylgalactosaminyltransferase 7
chr3_-_89905547 0.24 ENSMUST00000199740.2
ENSMUST00000198782.2
HCLS1 associated X-1
chr1_-_134883645 0.24 ENSMUST00000045665.13
ENSMUST00000086444.6
ENSMUST00000112163.2
protein phosphatase 1, regulatory subunit 12B
chr11_+_98689479 0.24 ENSMUST00000037930.13
male specific lethal 1
chr14_-_86986541 0.24 ENSMUST00000226254.2
diaphanous related formin 3
chr7_+_126550009 0.23 ENSMUST00000106332.3
seizure related 6 homolog like 2
chr18_+_37898633 0.23 ENSMUST00000044851.8
protocadherin gamma subfamily A, 12
chr12_+_55286111 0.23 ENSMUST00000164243.2
signal recognition particle 54C
chr6_+_134617903 0.23 ENSMUST00000062755.10
BLOC-1 related complex subunit 5
chr10_-_8632519 0.23 ENSMUST00000212869.2
SAM and SH3 domain containing 1
chr7_+_18962252 0.22 ENSMUST00000063976.9
optic atrophy 3
chr15_-_81244940 0.22 ENSMUST00000023040.9
solute carrier family 25 (mitochondrial carrier, peroxisomal membrane protein), member 17
chrX_-_50106844 0.22 ENSMUST00000053593.8
RAP2C, member of RAS oncogene family
chr2_-_87504008 0.22 ENSMUST00000213835.2
olfactory receptor 1135
chr7_+_100186399 0.22 ENSMUST00000120454.3
cytochrome c oxidase assembly factor 4
chr10_+_82669785 0.22 ENSMUST00000219368.3
thioredoxin reductase 1
chr19_+_26727111 0.22 ENSMUST00000175842.4
SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 2
chr10_-_107321938 0.22 ENSMUST00000000445.2
myogenic factor 5
chr15_+_65682066 0.22 ENSMUST00000211878.2
EFR3 homolog A
chr12_-_91815855 0.21 ENSMUST00000167466.2
ENSMUST00000021347.12
ENSMUST00000178462.8
sel-1 suppressor of lin-12-like (C. elegans)
chr7_-_108774367 0.21 ENSMUST00000207178.2
LIM domain only 1
chr16_-_22676264 0.21 ENSMUST00000232075.2
ENSMUST00000004576.8
TBCC domain containing 1
chr7_-_66915756 0.21 ENSMUST00000207715.2
myocyte enhancer factor 2A
chr7_-_103094646 0.21 ENSMUST00000215417.2
olfactory receptor 605
chr2_-_109108618 0.21 ENSMUST00000081631.10
methyltransferase like 15
chr19_+_41921903 0.21 ENSMUST00000224258.2
ENSMUST00000026154.9
ENSMUST00000224896.2
zinc finger, DHHC domain containing 16
chr9_+_65797519 0.21 ENSMUST00000045802.7
PCNA clamp associated factor
chr12_+_70499869 0.21 ENSMUST00000021471.13
thioredoxin-related transmembrane protein 1
chr5_-_138185686 0.21 ENSMUST00000110936.8
TATA-box binding protein associated factor 6
chr8_-_58106027 0.20 ENSMUST00000110316.3
polypeptide N-acetylgalactosaminyltransferase 7
chr13_+_42834039 0.20 ENSMUST00000128646.8
phosphatase and actin regulator 1
chr12_-_40087393 0.20 ENSMUST00000146905.2
ADP-ribosylation factor-like 4A
chr2_+_22959223 0.20 ENSMUST00000114523.10
acyl-Coenzyme A binding domain containing 5
chr9_-_103099262 0.20 ENSMUST00000170904.2
transferrin
chr10_+_127919142 0.20 ENSMUST00000026459.6
ATP synthase, H+ transporting mitochondrial F1 complex, beta subunit
chr11_+_70057449 0.20 ENSMUST00000102571.10
ENSMUST00000178945.8
ENSMUST00000000327.13
ENSMUST00000178567.3
C-type lectin domain family 10, member A
chr17_+_45817750 0.20 ENSMUST00000024733.9
alanyl-tRNA synthetase 2, mitochondrial
chr4_+_65523223 0.19 ENSMUST00000050850.14
ENSMUST00000107366.2
tripartite motif-containing 32
chr17_-_71305003 0.19 ENSMUST00000024846.13
ENSMUST00000232766.2
myosin, light chain 12A, regulatory, non-sarcomeric
chr2_+_83554741 0.19 ENSMUST00000028499.11
integrin alpha V
chr7_+_126549692 0.19 ENSMUST00000106335.8
ENSMUST00000146017.3
seizure related 6 homolog like 2
chr7_-_4909515 0.19 ENSMUST00000210663.2
predicted gene, 36210
chrX_-_135641869 0.19 ENSMUST00000166930.8
ENSMUST00000113095.8
mortality factor 4 like 2
chr8_-_85573489 0.18 ENSMUST00000003912.7
calreticulin
chr8_+_70625032 0.18 ENSMUST00000002413.15
ENSMUST00000182980.8
ENSMUST00000182365.8
transmembrane protein 161A
chr15_-_100322934 0.18 ENSMUST00000123461.8
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
chr16_+_23338960 0.18 ENSMUST00000211460.2
ENSMUST00000210658.2
ENSMUST00000209198.2
ENSMUST00000210371.2
ENSMUST00000211499.2
ENSMUST00000210795.2
ENSMUST00000209422.2
predicted gene 45338
receptor transporter protein 4
chr9_-_56151334 0.18 ENSMUST00000188142.7
pseudopodium-enriched atypical kinase 1
chr15_-_79658584 0.18 ENSMUST00000069877.12
dynein, axonemal, light chain 4
chr14_-_54651442 0.17 ENSMUST00000227334.2
solute carrier family 7 (cationic amino acid transporter, y+ system), member 7
chr7_+_51528788 0.17 ENSMUST00000107591.9
growth arrest specific 2
chr18_-_24736521 0.17 ENSMUST00000154205.2
solute carrier family 39 (metal ion transporter), member 6
chr13_+_94219934 0.17 ENSMUST00000156071.2
lipoma HMGIC fusion partner-like 2
chr1_-_149836974 0.16 ENSMUST00000190507.2
ENSMUST00000070200.15
phospholipase A2, group IVA (cytosolic, calcium-dependent)
chr14_+_26722319 0.16 ENSMUST00000035433.10
homeobox gene expressed in ES cells
chr2_-_84480804 0.16 ENSMUST00000066177.10
catenin (cadherin associated protein), delta 1
chrX_-_74460137 0.16 ENSMUST00000033542.11
mature T cell proliferation 1
chr8_+_84728123 0.16 ENSMUST00000060357.15
ENSMUST00000239176.2
RIKEN cDNA 1700067K01 gene
chr5_-_138169476 0.16 ENSMUST00000147920.2
minichromosome maintenance complex component 7
chr12_+_38830283 0.15 ENSMUST00000162563.8
ENSMUST00000161164.8
ENSMUST00000160996.8
ets variant 1
chr4_+_150938376 0.15 ENSMUST00000073600.9
ERBB receptor feedback inhibitor 1
chr3_+_109481223 0.15 ENSMUST00000106576.3
vav 3 oncogene
chr2_-_84481020 0.15 ENSMUST00000067232.10
catenin (cadherin associated protein), delta 1
chr17_+_79244553 0.15 ENSMUST00000024887.6
ENSMUST00000233068.2
ENSMUST00000233777.2
NADH:ubiquinone oxidoreductase complex assembly factor 7
chr18_+_23548455 0.15 ENSMUST00000115832.4
dystrobrevin alpha
chr9_-_110453427 0.15 ENSMUST00000196876.2
ENSMUST00000035069.14
neurotrophin receptor associated death domain
chr5_+_88731386 0.15 ENSMUST00000031229.11
RUN and FYVE domain containing 3
chr6_-_50433064 0.15 ENSMUST00000146341.4
ENSMUST00000071728.11
oxysterol binding protein-like 3
chr3_+_68598757 0.14 ENSMUST00000107816.4
interleukin 12a
chr8_+_22682816 0.14 ENSMUST00000033866.9
vacuolar protein sorting 36
chr3_-_33898405 0.14 ENSMUST00000029222.8
coiled-coil domain containing 39
chr13_-_113063890 0.14 ENSMUST00000022281.5
Mtr4 exosome RNA helicase
chr2_-_125701059 0.14 ENSMUST00000110463.8
ENSMUST00000028635.6
COP9 signalosome subunit 2
chr13_+_38388904 0.14 ENSMUST00000091641.13
ENSMUST00000178564.2
small nuclear ribonucleoprotein 48 (U11/U12)
chr7_-_108529375 0.14 ENSMUST00000055745.5
NLR family, pyrin domain containing 10
chr17_+_38104420 0.14 ENSMUST00000216051.3
olfactory receptor 123
chr6_-_148732946 0.14 ENSMUST00000048418.14
importin 8
chr5_-_123127346 0.14 ENSMUST00000118027.8
lysine (K)-specific demethylase 2B
chr19_-_46958001 0.14 ENSMUST00000235234.2
5'-nucleotidase, cytosolic II
chr3_-_88332401 0.13 ENSMUST00000168755.7
ENSMUST00000193433.6
ENSMUST00000195657.6
ENSMUST00000057935.9
solute carrier family 25, member 44
chr5_+_14075281 0.13 ENSMUST00000073957.8
sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E
chr6_-_56900917 0.13 ENSMUST00000031793.8
5'-nucleotidase, cytosolic III
chr14_+_54701594 0.13 ENSMUST00000022782.10
low-density lipoprotein receptor-related protein 10
chr6_-_71417607 0.13 ENSMUST00000002292.15
required for meiotic nuclear division 5 homolog A
chr19_-_46950948 0.13 ENSMUST00000236924.2
5'-nucleotidase, cytosolic II
chr11_-_116080361 0.13 ENSMUST00000148601.2
acyl-Coenzyme A oxidase 1, palmitoyl

Network of associatons between targets according to the STRING database.

First level regulatory network of Gbx1_Nobox_Alx3

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.4 GO:0044878 mitotic cytokinesis checkpoint(GO:0044878)
0.4 1.1 GO:2000729 positive regulation of mesenchymal cell proliferation involved in ureter development(GO:2000729)
0.3 0.8 GO:0061357 positive regulation of Wnt protein secretion(GO:0061357)
0.2 0.7 GO:0060448 dichotomous subdivision of terminal units involved in lung branching(GO:0060448)
0.2 0.6 GO:0043973 histone H3-K4 acetylation(GO:0043973)
0.2 1.3 GO:2001205 negative regulation of osteoclast development(GO:2001205)
0.2 0.9 GO:0070966 nuclear-transcribed mRNA catabolic process, no-go decay(GO:0070966)
0.2 1.0 GO:0035633 maintenance of blood-brain barrier(GO:0035633)
0.1 0.5 GO:0090063 positive regulation of microtubule nucleation(GO:0090063)
0.1 0.4 GO:0044029 DNA hypomethylation(GO:0044028) hypomethylation of CpG island(GO:0044029)
0.1 0.6 GO:0051684 maintenance of Golgi location(GO:0051684)
0.1 0.7 GO:0035553 oxidative single-stranded RNA demethylation(GO:0035553)
0.1 0.3 GO:0015825 L-serine transport(GO:0015825)
0.1 0.4 GO:0032468 cellular manganese ion homeostasis(GO:0030026) Golgi calcium ion homeostasis(GO:0032468) manganese ion homeostasis(GO:0055071)
0.1 0.6 GO:0060690 epithelial cell differentiation involved in salivary gland development(GO:0060690)
0.1 0.5 GO:0002485 antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway(GO:0002484) antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent(GO:0002485)
0.1 1.0 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.1 1.1 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.1 0.4 GO:0046098 guanine metabolic process(GO:0046098)
0.1 0.6 GO:1900739 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.1 0.2 GO:0072356 chromosome passenger complex localization to kinetochore(GO:0072356)
0.1 0.3 GO:0046725 modulation by host of viral RNA genome replication(GO:0044830) negative regulation by virus of viral protein levels in host cell(GO:0046725)
0.1 0.4 GO:0038032 termination of G-protein coupled receptor signaling pathway(GO:0038032)
0.1 0.5 GO:0042663 regulation of endodermal cell fate specification(GO:0042663)
0.1 0.6 GO:0009249 protein lipoylation(GO:0009249)
0.1 0.2 GO:0006419 alanyl-tRNA aminoacylation(GO:0006419)
0.1 0.3 GO:0070358 actin polymerization-dependent cell motility(GO:0070358)
0.1 0.5 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.1 0.2 GO:0002396 MHC protein complex assembly(GO:0002396) peptide antigen assembly with MHC protein complex(GO:0002501)
0.1 0.2 GO:1901421 positive regulation of response to alcohol(GO:1901421)
0.1 0.6 GO:0030242 pexophagy(GO:0030242)
0.1 0.6 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.1 0.3 GO:0015676 vanadium ion transport(GO:0015676) lead ion transport(GO:0015692)
0.0 0.1 GO:0019918 peptidyl-arginine methylation, to symmetrical-dimethyl arginine(GO:0019918)
0.0 0.2 GO:0002248 connective tissue replacement involved in inflammatory response wound healing(GO:0002248)
0.0 0.4 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.3 GO:0035887 aortic smooth muscle cell differentiation(GO:0035887)
0.0 0.2 GO:1902498 regulation of protein autoubiquitination(GO:1902498)
0.0 0.3 GO:0098734 protein depalmitoylation(GO:0002084) macromolecule depalmitoylation(GO:0098734)
0.0 0.8 GO:0006337 nucleosome disassembly(GO:0006337)
0.0 0.5 GO:0032049 cardiolipin biosynthetic process(GO:0032049)
0.0 0.2 GO:0035660 MyD88-dependent toll-like receptor 4 signaling pathway(GO:0035660)
0.0 1.7 GO:0006099 tricarboxylic acid cycle(GO:0006099)
0.0 0.2 GO:0055005 ventricular cardiac myofibril assembly(GO:0055005)
0.0 0.8 GO:1903504 regulation of mitotic cell cycle spindle assembly checkpoint(GO:0090266) regulation of mitotic spindle checkpoint(GO:1903504)
0.0 0.2 GO:1902261 positive regulation of delayed rectifier potassium channel activity(GO:1902261)
0.0 0.6 GO:0042541 hemoglobin biosynthetic process(GO:0042541)
0.0 1.0 GO:0002230 positive regulation of defense response to virus by host(GO:0002230)
0.0 0.4 GO:2000582 regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000580) positive regulation of ATP-dependent microtubule motor activity, plus-end-directed(GO:2000582)
0.0 0.1 GO:1903173 phytol metabolic process(GO:0033306) fatty alcohol metabolic process(GO:1903173)
0.0 0.2 GO:0015867 ATP transport(GO:0015867)
0.0 0.1 GO:2001200 positive regulation of dendritic cell differentiation(GO:2001200)
0.0 0.1 GO:0043328 protein targeting to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway(GO:0043328)
0.0 0.3 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.0 0.3 GO:0046874 quinolinate metabolic process(GO:0046874)
0.0 0.1 GO:0021993 initiation of neural tube closure(GO:0021993)
0.0 0.3 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.0 0.2 GO:0070447 positive regulation of oligodendrocyte progenitor proliferation(GO:0070447)
0.0 0.1 GO:0001966 thigmotaxis(GO:0001966)
0.0 0.2 GO:0031394 positive regulation of prostaglandin biosynthetic process(GO:0031394) positive regulation of unsaturated fatty acid biosynthetic process(GO:2001280)
0.0 0.3 GO:0032876 negative regulation of DNA endoreduplication(GO:0032876)
0.0 0.1 GO:0051919 positive regulation of fibrinolysis(GO:0051919)
0.0 0.3 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.0 0.2 GO:0016259 selenocysteine metabolic process(GO:0016259)
0.0 0.3 GO:1902172 keratinocyte apoptotic process(GO:0097283) regulation of keratinocyte apoptotic process(GO:1902172)
0.0 0.2 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.0 0.2 GO:0046013 regulation of T cell homeostatic proliferation(GO:0046013)
0.0 0.2 GO:0051697 protein delipidation(GO:0051697)
0.0 0.3 GO:0035520 monoubiquitinated protein deubiquitination(GO:0035520)
0.0 0.9 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 1.2 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 1.0 GO:0050860 negative regulation of T cell receptor signaling pathway(GO:0050860)
0.0 0.2 GO:0000821 regulation of arginine metabolic process(GO:0000821)
0.0 0.2 GO:0006933 negative regulation of cell adhesion involved in substrate-bound cell migration(GO:0006933)
0.0 0.1 GO:1903537 meiotic cell cycle process involved in oocyte maturation(GO:1903537) regulation of meiotic cell cycle process involved in oocyte maturation(GO:1903538)
0.0 0.4 GO:0043983 histone H4-K12 acetylation(GO:0043983)
0.0 0.2 GO:0010616 negative regulation of cardiac muscle adaptation(GO:0010616) negative regulation of cardiac muscle hypertrophy in response to stress(GO:1903243)
0.0 0.6 GO:0001553 luteinization(GO:0001553)
0.0 0.1 GO:0051135 positive regulation of NK T cell activation(GO:0051135)
0.0 0.4 GO:0071578 zinc II ion transmembrane import(GO:0071578)
0.0 0.3 GO:0030854 positive regulation of granulocyte differentiation(GO:0030854)
0.0 0.1 GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase(GO:0033540)
0.0 0.1 GO:0099527 postsynapse to nucleus signaling pathway(GO:0099527)
0.0 0.4 GO:1901299 negative regulation of hydrogen peroxide-mediated programmed cell death(GO:1901299)
0.0 0.1 GO:0060287 determination of pancreatic left/right asymmetry(GO:0035469) epithelial cilium movement involved in determination of left/right asymmetry(GO:0060287)
0.0 0.4 GO:0031987 locomotion involved in locomotory behavior(GO:0031987)
0.0 0.1 GO:0052055 modulation by symbiont of host molecular function(GO:0052055) modulation of catalytic activity in other organism involved in symbiotic interaction(GO:0052203) modulation by host of symbiont catalytic activity(GO:0052422)
0.0 0.3 GO:1902083 negative regulation of peptidyl-cysteine S-nitrosylation(GO:1902083)
0.0 0.1 GO:2000318 positive regulation of T-helper 17 type immune response(GO:2000318)
0.0 0.3 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.1 GO:1902962 regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902962) negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process(GO:1902963)
0.0 0.2 GO:0070475 rRNA base methylation(GO:0070475)
0.0 0.4 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.3 GO:0090557 establishment of endothelial intestinal barrier(GO:0090557)
0.0 0.5 GO:2000114 regulation of establishment of cell polarity(GO:2000114)
0.0 0.0 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.0 0.0 GO:0021524 visceral motor neuron differentiation(GO:0021524)
0.0 0.6 GO:0090200 positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.0 0.1 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
0.0 0.0 GO:1900377 negative regulation of melanin biosynthetic process(GO:0048022) negative regulation of secondary metabolite biosynthetic process(GO:1900377)
0.0 0.3 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.4 GO:0090036 regulation of protein kinase C signaling(GO:0090036)
0.0 0.5 GO:0031146 SCF-dependent proteasomal ubiquitin-dependent protein catabolic process(GO:0031146)
0.0 1.1 GO:0046580 negative regulation of Ras protein signal transduction(GO:0046580)
0.0 0.4 GO:0001580 detection of chemical stimulus involved in sensory perception of bitter taste(GO:0001580)
0.0 0.4 GO:0097062 dendritic spine maintenance(GO:0097062)
0.0 0.4 GO:0016339 calcium-dependent cell-cell adhesion via plasma membrane cell adhesion molecules(GO:0016339)
0.0 0.2 GO:0019985 translesion synthesis(GO:0019985)
0.0 0.1 GO:0030853 negative regulation of granulocyte differentiation(GO:0030853)
0.0 0.4 GO:0016556 mRNA modification(GO:0016556)
0.0 0.2 GO:0018026 peptidyl-lysine monomethylation(GO:0018026)
0.0 0.2 GO:0033617 mitochondrial respiratory chain complex IV assembly(GO:0033617)
0.0 0.1 GO:0070562 regulation of vitamin D receptor signaling pathway(GO:0070562)
0.0 0.0 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.0 0.3 GO:0043968 histone H2A acetylation(GO:0043968)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:1903754 cortical microtubule plus-end(GO:1903754) cytoplasmic microtubule plus-end(GO:1904511)
0.2 0.7 GO:0060187 cell pole(GO:0060187)
0.1 0.4 GO:0005943 phosphatidylinositol 3-kinase complex, class IA(GO:0005943)
0.1 0.5 GO:0008623 CHRAC(GO:0008623)
0.1 1.4 GO:0000815 ESCRT III complex(GO:0000815)
0.1 0.6 GO:0000172 ribonuclease MRP complex(GO:0000172)
0.1 1.8 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.1 0.9 GO:0045252 oxoglutarate dehydrogenase complex(GO:0045252)
0.1 0.2 GO:0034680 integrin alpha10-beta1 complex(GO:0034680)
0.1 0.8 GO:0016272 prefoldin complex(GO:0016272)
0.1 0.2 GO:0005863 striated muscle myosin thick filament(GO:0005863)
0.1 0.4 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.1 0.3 GO:0070826 paraferritin complex(GO:0070826)
0.1 0.8 GO:0042555 MCM complex(GO:0042555)
0.0 1.1 GO:0031235 intrinsic component of the cytoplasmic side of the plasma membrane(GO:0031235)
0.0 0.1 GO:0000814 ESCRT II complex(GO:0000814)
0.0 0.7 GO:0005915 zonula adherens(GO:0005915)
0.0 0.2 GO:0000839 Hrd1p ubiquitin ligase ERAD-L complex(GO:0000839)
0.0 0.5 GO:0042612 MHC class I protein complex(GO:0042612)
0.0 0.3 GO:0033093 Weibel-Palade body(GO:0033093)
0.0 0.5 GO:0005869 dynactin complex(GO:0005869)
0.0 1.3 GO:0005921 gap junction(GO:0005921)
0.0 0.2 GO:0072487 MSL complex(GO:0072487)
0.0 0.2 GO:0098574 cytoplasmic side of lysosomal membrane(GO:0098574)
0.0 0.4 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.1 GO:0071821 FANCM-MHF complex(GO:0071821)
0.0 0.3 GO:0097433 dense body(GO:0097433)
0.0 0.1 GO:0034657 GID complex(GO:0034657)
0.0 0.4 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.8 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.6 GO:0033276 transcription factor TFTC complex(GO:0033276)
0.0 0.5 GO:0071437 invadopodium(GO:0071437)
0.0 0.2 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.0 0.2 GO:0042824 MHC class I peptide loading complex(GO:0042824)
0.0 1.4 GO:0005834 heterotrimeric G-protein complex(GO:0005834)
0.0 0.3 GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.0 0.1 GO:0032937 SREBP-SCAP-Insig complex(GO:0032937)
0.0 0.1 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.0 0.3 GO:0005662 DNA replication factor A complex(GO:0005662)
0.0 0.8 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.1 GO:0032777 Piccolo NuA4 histone acetyltransferase complex(GO:0032777)
0.0 0.1 GO:0070381 endosome to plasma membrane transport vesicle(GO:0070381)
0.0 0.0 GO:0034457 Mpp10 complex(GO:0034457)
0.0 0.4 GO:1990124 messenger ribonucleoprotein complex(GO:1990124)
0.0 1.0 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.0 0.3 GO:0071564 npBAF complex(GO:0071564)
0.0 0.2 GO:0031258 lamellipodium membrane(GO:0031258)
0.0 0.3 GO:0017146 NMDA selective glutamate receptor complex(GO:0017146)
0.0 0.2 GO:1990023 mitotic spindle midzone(GO:1990023)
0.0 0.5 GO:0055038 recycling endosome membrane(GO:0055038)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0003870 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.2 0.6 GO:0000171 ribonuclease MRP activity(GO:0000171)
0.1 0.9 GO:0004591 oxoglutarate dehydrogenase (succinyl-transferring) activity(GO:0004591)
0.1 0.7 GO:0035515 oxidative RNA demethylase activity(GO:0035515)
0.1 0.8 GO:0046912 transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer(GO:0046912)
0.1 0.4 GO:0015410 manganese-transporting ATPase activity(GO:0015410)
0.1 0.3 GO:0033149 FFAT motif binding(GO:0033149)
0.1 0.5 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.1 0.4 GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.1 0.1 GO:0015173 aromatic amino acid transmembrane transporter activity(GO:0015173)
0.1 0.4 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.1 0.3 GO:0032422 purine-rich negative regulatory element binding(GO:0032422)
0.1 0.2 GO:0004813 alanine-tRNA ligase activity(GO:0004813)
0.1 0.7 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.1 0.8 GO:0031852 mu-type opioid receptor binding(GO:0031852)
0.1 0.2 GO:0033797 selenate reductase activity(GO:0033797)
0.1 0.3 GO:0015100 cadmium ion transmembrane transporter activity(GO:0015086) lead ion transmembrane transporter activity(GO:0015094) vanadium ion transmembrane transporter activity(GO:0015100) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.0 0.2 GO:0043532 angiostatin binding(GO:0043532)
0.0 0.8 GO:0003688 DNA replication origin binding(GO:0003688)
0.0 0.4 GO:0019158 fructokinase activity(GO:0008865) mannokinase activity(GO:0019158)
0.0 0.2 GO:0051185 coenzyme transporter activity(GO:0051185)
0.0 0.7 GO:0030274 LIM domain binding(GO:0030274)
0.0 1.0 GO:0002162 dystroglycan binding(GO:0002162)
0.0 0.2 GO:0016434 rRNA (cytosine) methyltransferase activity(GO:0016434)
0.0 0.2 GO:0098639 collagen binding involved in cell-matrix adhesion(GO:0098639)
0.0 0.5 GO:0004908 interleukin-1 receptor activity(GO:0004908)
0.0 0.3 GO:0015193 L-alanine transmembrane transporter activity(GO:0015180) L-proline transmembrane transporter activity(GO:0015193) alanine transmembrane transporter activity(GO:0022858)
0.0 0.7 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.3 GO:0004568 chitinase activity(GO:0004568)
0.0 0.5 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.1 GO:0035243 protein-arginine omega-N symmetric methyltransferase activity(GO:0035243)
0.0 0.4 GO:0046934 phosphatidylinositol-4,5-bisphosphate 3-kinase activity(GO:0046934) phosphatidylinositol bisphosphate kinase activity(GO:0052813)
0.0 0.1 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.0 0.1 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.0 0.4 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.2 GO:0072510 ferric iron transmembrane transporter activity(GO:0015091) trivalent inorganic cation transmembrane transporter activity(GO:0072510)
0.0 0.5 GO:0046977 TAP binding(GO:0046977)
0.0 1.1 GO:0001223 transcription coactivator binding(GO:0001223)
0.0 0.3 GO:0008474 palmitoyl-(protein) hydrolase activity(GO:0008474) palmitoyl hydrolase activity(GO:0098599)
0.0 0.2 GO:0019966 interleukin-1 binding(GO:0019966)
0.0 1.8 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 0.1 GO:0005174 CD40 receptor binding(GO:0005174)
0.0 0.4 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.2 GO:0031849 olfactory receptor binding(GO:0031849)
0.0 0.6 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.0 0.1 GO:0016401 palmitoyl-CoA oxidase activity(GO:0016401)
0.0 1.2 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.6 GO:0000062 fatty-acyl-CoA binding(GO:0000062)
0.0 0.2 GO:0046975 histone methyltransferase activity (H3-K36 specific)(GO:0046975)
0.0 0.8 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.3 GO:0017017 MAP kinase tyrosine/serine/threonine phosphatase activity(GO:0017017)
0.0 0.1 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.0 0.2 GO:0047498 calcium-dependent phospholipase A2 activity(GO:0047498)
0.0 0.3 GO:0019825 oxygen binding(GO:0019825)
0.0 0.4 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.5 GO:0016780 phosphotransferase activity, for other substituted phosphate groups(GO:0016780)
0.0 0.4 GO:0070628 proteasome binding(GO:0070628)
0.0 0.4 GO:0008574 ATP-dependent microtubule motor activity, plus-end-directed(GO:0008574)
0.0 0.1 GO:0034056 estrogen response element binding(GO:0034056)
0.0 1.7 GO:0004197 cysteine-type endopeptidase activity(GO:0004197)
0.0 0.0 GO:0001571 non-tyrosine kinase fibroblast growth factor receptor activity(GO:0001571)
0.0 1.0 GO:0004601 peroxidase activity(GO:0004601)
0.0 0.3 GO:0016208 AMP binding(GO:0016208)
0.0 0.5 GO:0070840 dynein complex binding(GO:0070840)
0.0 0.2 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.4 GO:0000993 RNA polymerase II core binding(GO:0000993)
0.0 0.1 GO:0061665 SUMO ligase activity(GO:0061665)
0.0 0.6 GO:0008536 Ran GTPase binding(GO:0008536)
0.0 0.0 GO:0030519 snoRNP binding(GO:0030519)
0.0 1.9 GO:0017048 Rho GTPase binding(GO:0017048)
0.0 0.4 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.1 GO:0015016 [heparan sulfate]-glucosamine N-sulfotransferase activity(GO:0015016)
0.0 0.1 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 1.3 GO:0051082 unfolded protein binding(GO:0051082)
0.0 0.8 GO:0001105 RNA polymerase II transcription coactivator activity(GO:0001105)
0.0 0.2 GO:0015174 basic amino acid transmembrane transporter activity(GO:0015174)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.4 ST INTERFERON GAMMA PATHWAY Interferon gamma pathway.
0.0 1.5 PID NCADHERIN PATHWAY N-cadherin signaling events
0.0 1.1 PID RAS PATHWAY Regulation of Ras family activation
0.0 0.9 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 0.8 PID ATR PATHWAY ATR signaling pathway
0.0 1.4 PID MYC REPRESS PATHWAY Validated targets of C-MYC transcriptional repression
0.0 0.4 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 0.4 PID IL12 STAT4 PATHWAY IL12 signaling mediated by STAT4
0.0 0.5 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.6 ST ERK1 ERK2 MAPK PATHWAY ERK1/ERK2 MAPK Pathway
0.0 1.4 PID CXCR4 PATHWAY CXCR4-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.3 REACTOME APOPTOTIC CLEAVAGE OF CELL ADHESION PROTEINS Genes involved in Apoptotic cleavage of cell adhesion proteins
0.1 0.8 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.0 1.6 REACTOME ENDOSOMAL SORTING COMPLEX REQUIRED FOR TRANSPORT ESCRT Genes involved in Endosomal Sorting Complex Required For Transport (ESCRT)
0.0 1.3 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 0.8 REACTOME CITRIC ACID CYCLE TCA CYCLE Genes involved in Citric acid cycle (TCA cycle)
0.0 0.3 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.6 REACTOME ACYL CHAIN REMODELLING OF PG Genes involved in Acyl chain remodelling of PG
0.0 0.9 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.6 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 0.3 REACTOME TRYPTOPHAN CATABOLISM Genes involved in Tryptophan catabolism
0.0 0.4 REACTOME RETROGRADE NEUROTROPHIN SIGNALLING Genes involved in Retrograde neurotrophin signalling
0.0 0.5 REACTOME INTRINSIC PATHWAY Genes involved in Intrinsic Pathway
0.0 0.6 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 0.1 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.0 0.5 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.2 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 0.5 REACTOME TIE2 SIGNALING Genes involved in Tie2 Signaling
0.0 0.4 REACTOME ZINC TRANSPORTERS Genes involved in Zinc transporters
0.0 0.3 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.9 REACTOME ACTIVATION OF CHAPERONE GENES BY XBP1S Genes involved in Activation of Chaperone Genes by XBP1(S)
0.0 0.3 REACTOME ERKS ARE INACTIVATED Genes involved in ERKs are inactivated
0.0 1.0 REACTOME PHASE1 FUNCTIONALIZATION OF COMPOUNDS Genes involved in Phase 1 - Functionalization of compounds
0.0 0.1 REACTOME THE ACTIVATION OF ARYLSULFATASES Genes involved in The activation of arylsulfatases
0.0 0.1 REACTOME APOPTOSIS INDUCED DNA FRAGMENTATION Genes involved in Apoptosis induced DNA fragmentation
0.0 0.6 REACTOME RNA POL II TRANSCRIPTION PRE INITIATION AND PROMOTER OPENING Genes involved in RNA Polymerase II Transcription Pre-Initiation And Promoter Opening