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avrg: GFI1 WT vs 36n/n vs KD

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Results for Glis2

Z-value: 0.92

Motif logo

Transcription factors associated with Glis2

Gene Symbol Gene ID Gene Info
ENSMUSG00000014303.14 GLIS family zinc finger 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Glis2mm39_v1_chr16_+_4412546_4412599-0.847.2e-02Click!

Activity profile of Glis2 motif

Sorted Z-values of Glis2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr7_-_126303887 0.76 ENSMUST00000131415.8
coronin, actin binding protein 1A
chr11_+_87684548 0.70 ENSMUST00000143021.9
myeloperoxidase
chr7_+_127345909 0.52 ENSMUST00000033081.14
F-box and leucine-rich repeat protein 19
chr17_-_65901946 0.51 ENSMUST00000232686.2
vesicle-associated membrane protein, associated protein A
chr17_+_26882171 0.51 ENSMUST00000236346.2
ATPase, H+ transporting, lysosomal V0 subunit E
chr10_+_79650496 0.50 ENSMUST00000218857.2
ENSMUST00000220365.2
paralemmin
chr5_-_137531463 0.46 ENSMUST00000170293.8
guanine nucleotide binding protein (G protein), beta 2
chr1_-_93729562 0.45 ENSMUST00000112890.3
deoxythymidylate kinase
chr4_-_15945359 0.43 ENSMUST00000029877.9
2,4-dienoyl CoA reductase 1, mitochondrial
chr11_+_4823951 0.43 ENSMUST00000038570.9
nipsnap homolog 1
chr7_+_141056305 0.42 ENSMUST00000117634.2
tetraspanin 4
chr6_-_124410452 0.42 ENSMUST00000124998.2
ENSMUST00000238807.2
calsyntenin 3
chr16_+_32698470 0.40 ENSMUST00000232272.2
forty-two-three domain containing 1
chr5_-_137531413 0.39 ENSMUST00000168746.8
guanine nucleotide binding protein (G protein), beta 2
chr1_-_118239146 0.38 ENSMUST00000027623.9
translin
chr2_+_90507552 0.37 ENSMUST00000057481.7
nucleoporin 160
chr12_-_31684588 0.37 ENSMUST00000020979.9
ENSMUST00000177962.9
B cell receptor associated protein 29
chr5_-_124490296 0.36 ENSMUST00000111472.6
CDK2 (cyclin-dependent kinase 2)-associated protein 1
chr11_+_98932586 0.35 ENSMUST00000177092.8
insulin-like growth factor binding protein 4
chr17_-_26014613 0.35 ENSMUST00000235889.2
predicted gene, 50367
chr12_-_80690573 0.34 ENSMUST00000166931.2
ENSMUST00000218364.2
ERH mRNA splicing and mitosis factor
chr6_-_29212295 0.34 ENSMUST00000078155.12
inosine monophosphate dehydrogenase 1
chr17_+_7246365 0.32 ENSMUST00000232245.2
ribonuclease T2B
chr14_-_31362835 0.31 ENSMUST00000167066.8
ENSMUST00000127204.9
2-hydroxyacyl-CoA lyase 1
chr7_+_27290969 0.30 ENSMUST00000108344.9
thymoma viral proto-oncogene 2
chr10_+_127157784 0.30 ENSMUST00000219511.2
Rho GTPase activating protein 9
chr1_-_131204651 0.28 ENSMUST00000161764.8
inhibitor of kappaB kinase epsilon
chr14_+_55120875 0.27 ENSMUST00000134077.2
ENSMUST00000172844.8
ENSMUST00000133397.4
ENSMUST00000227108.2
predicted gene 20521
BCL2-like 2
chr6_-_29212239 0.27 ENSMUST00000160878.8
inosine monophosphate dehydrogenase 1
chr3_+_94882142 0.27 ENSMUST00000167008.8
ENSMUST00000107251.9
phosphatidylinositol 4-kinase beta
chr17_+_7246289 0.26 ENSMUST00000179728.2
ribonuclease T2B
chr5_-_134643805 0.26 ENSMUST00000202085.2
ENSMUST00000036362.13
ENSMUST00000077636.8
linker for activation of T cells family, member 2
chr9_+_75213570 0.25 ENSMUST00000213990.2
guanine nucleotide binding protein (G protein), beta 5
chr5_+_115417725 0.25 ENSMUST00000040421.11
coenzyme Q5 methyltransferase
chrX_-_166165743 0.24 ENSMUST00000026839.5
phosphoribosyl pyrophosphate synthetase 2
chr9_+_21634779 0.24 ENSMUST00000034713.9
low density lipoprotein receptor
chr9_+_21634918 0.24 ENSMUST00000213114.2
low density lipoprotein receptor
chr7_+_27291126 0.24 ENSMUST00000167435.8
thymoma viral proto-oncogene 2
chr12_+_73170483 0.24 ENSMUST00000187549.7
ENSMUST00000021523.7
menage a trois 1
chr17_-_8366536 0.24 ENSMUST00000231927.2
ribonuclease T2A
chrX_-_106446928 0.23 ENSMUST00000033591.6
integral membrane protein 2A
chr3_+_127584251 0.23 ENSMUST00000164447.3
TRAF-interacting protein with forkhead-associated domain
chr11_-_70560110 0.23 ENSMUST00000129434.2
ENSMUST00000018431.13
sperm associated antigen 7
chr10_+_127102193 0.22 ENSMUST00000026479.11
dynactin 2
chr8_+_73488496 0.22 ENSMUST00000058099.9
coagulation factor II (thrombin) receptor-like 3
chr13_-_53083494 0.22 ENSMUST00000123599.8
AU RNA binding protein/enoyl-coenzyme A hydratase
chr6_-_148732946 0.22 ENSMUST00000048418.14
importin 8
chr14_-_8536869 0.21 ENSMUST00000238865.2
ENSMUST00000159275.4
predicted gene 11100
chr8_-_23747023 0.21 ENSMUST00000121783.7
golgi autoantigen, golgin subfamily a, 7
chr17_-_31731222 0.21 ENSMUST00000236665.2
WD repeat domain 4
chr1_+_135945798 0.20 ENSMUST00000117950.2
transmembrane protein 9
chr10_+_13376745 0.20 ENSMUST00000060212.13
ENSMUST00000121465.3
fucosidase, alpha-L- 2, plasma
chr1_-_84817000 0.20 ENSMUST00000186648.7
thyroid hormone receptor interactor 12
chr19_+_45991907 0.20 ENSMUST00000099393.4
HPS6, biogenesis of lysosomal organelles complex 2 subunit 3
chr7_-_126398165 0.20 ENSMUST00000205890.2
ENSMUST00000205336.2
ENSMUST00000087566.11
aldolase A, fructose-bisphosphate
chr9_+_50768224 0.19 ENSMUST00000174628.8
ENSMUST00000034560.14
ENSMUST00000114437.9
ENSMUST00000175645.8
ENSMUST00000176349.8
ENSMUST00000176798.8
ENSMUST00000175640.8
protein phosphatase 2, regulatory subunit A, beta
chr9_+_107852733 0.19 ENSMUST00000035216.11
ubiquitin-like modifier activating enzyme 7
chr8_-_85413707 0.19 ENSMUST00000238301.2
nucleus accumbens associated 1, BEN and BTB (POZ) domain containing
chr1_+_135945705 0.19 ENSMUST00000063719.15
transmembrane protein 9
chr7_-_121700958 0.19 ENSMUST00000139456.2
ENSMUST00000106471.9
ENSMUST00000123296.8
ENSMUST00000033157.10
NADH:ubiquinone oxidoreductase subunit AB1
chr19_+_8713156 0.18 ENSMUST00000210512.2
ENSMUST00000049424.11
WD repeat domain 74
chr11_+_70416185 0.18 ENSMUST00000018430.7
proteasome (prosome, macropain) subunit, beta type 6
chr9_+_25392843 0.18 ENSMUST00000040677.6
endonuclease/exonuclease/phosphatase family domain containing 1
chr4_-_42661893 0.18 ENSMUST00000108006.4
interleukin 11 receptor, alpha chain 2
chr10_+_93669680 0.18 ENSMUST00000216224.2
ubiquitin specific peptidase 44
chr16_+_17577464 0.18 ENSMUST00000129199.8
kelch-like 22
chr2_-_152672535 0.17 ENSMUST00000146380.2
ENSMUST00000134902.2
ENSMUST00000134357.2
ENSMUST00000109820.5
BCL2-like 1
chr6_+_136305516 0.17 ENSMUST00000204966.2
ENSMUST00000077886.7
eukaryotic translation initiation factor 4A3 like 1
chr17_+_34258411 0.17 ENSMUST00000087497.11
ENSMUST00000131134.9
ENSMUST00000235819.2
ENSMUST00000114255.9
ENSMUST00000114252.9
ENSMUST00000237989.2
collagen, type XI, alpha 2
chr6_-_48817675 0.17 ENSMUST00000203265.3
ENSMUST00000205159.3
transmembrane protein 176B
chr14_-_31362909 0.17 ENSMUST00000022437.16
2-hydroxyacyl-CoA lyase 1
chr5_+_125552878 0.16 ENSMUST00000031445.5
acetoacetyl-CoA synthetase
chr10_+_80971054 0.16 ENSMUST00000125261.2
zinc finger and BTB domain containing 7a
chr7_-_141614758 0.16 ENSMUST00000211000.2
ENSMUST00000209725.2
ENSMUST00000084418.4
MOB kinase activator 2
chr10_+_36850532 0.15 ENSMUST00000019911.14
ENSMUST00000105510.2
histone deacetylase 2
chr14_+_31363004 0.15 ENSMUST00000090147.7
biotinidase
chr7_+_144468837 0.15 ENSMUST00000128057.8
ENSMUST00000033388.12
ENSMUST00000141737.2
ENSMUST00000105895.2
ABCE maturation factor
chr5_-_110987441 0.15 ENSMUST00000145318.2
HscB iron-sulfur cluster co-chaperone
chr3_-_90416757 0.15 ENSMUST00000107343.8
ENSMUST00000001043.14
ENSMUST00000107344.8
ENSMUST00000076639.11
ENSMUST00000107346.8
ENSMUST00000146740.8
ENSMUST00000107342.2
ENSMUST00000049937.13
chromatin target of PRMT1
chr2_+_112092271 0.14 ENSMUST00000028553.4
NOP10 ribonucleoprotein
chr11_-_102209767 0.14 ENSMUST00000174302.8
ENSMUST00000178839.8
ENSMUST00000006754.14
upstream binding transcription factor, RNA polymerase I
chr6_+_113581708 0.14 ENSMUST00000035725.7
BRICK1, SCAR/WAVE actin-nucleating complex subunit
chr8_-_72178340 0.14 ENSMUST00000153800.8
ENSMUST00000146100.8
FCH domain only 1
chr10_+_126914755 0.13 ENSMUST00000039259.7
ENSMUST00000217941.2
ArfGAP with GTPase domain, ankyrin repeat and PH domain 2
chr4_+_118477994 0.12 ENSMUST00000030501.15
EBNA1 binding protein 2
chr2_-_29142965 0.12 ENSMUST00000155949.2
ENSMUST00000154682.8
ENSMUST00000028141.6
ENSMUST00000071201.5
RIKEN cDNA 6530402F18 gene
netrin G2
chr6_+_48818567 0.12 ENSMUST00000203639.3
transmembrane protein 176A
chr10_-_128047658 0.12 ENSMUST00000061995.10
SPRY domain containing 4
chr3_+_66888685 0.12 ENSMUST00000162036.8
arginine/serine-rich coiled-coil 1
chr4_-_128856213 0.12 ENSMUST00000119354.8
ENSMUST00000106068.8
ENSMUST00000030581.10
antizyme inhibitor 2
chr7_+_25016492 0.11 ENSMUST00000128119.2
multiple EGF-like-domains 8
chr16_+_17577493 0.11 ENSMUST00000165790.9
kelch-like 22
chr14_+_54457978 0.11 ENSMUST00000103740.2
ENSMUST00000198398.5
T cell receptor alpha constant
chr5_-_110987604 0.11 ENSMUST00000056937.12
HscB iron-sulfur cluster co-chaperone
chr1_-_93729650 0.11 ENSMUST00000027503.14
deoxythymidylate kinase
chr10_-_22607136 0.11 ENSMUST00000238910.2
ENSMUST00000127698.8
novel protein
TATA box binding protein-like 1
chr19_+_7245591 0.11 ENSMUST00000066646.12
REST corepressor 2
chr6_-_106777014 0.11 ENSMUST00000013882.10
ENSMUST00000113239.10
cereblon
chr7_+_5060159 0.11 ENSMUST00000045543.8
coiled-coil domain containing 106
chr7_-_19595221 0.10 ENSMUST00000014830.8
carcinoembryonic antigen-related cell adhesion molecule 16
chr2_+_119181703 0.10 ENSMUST00000028780.4
ChaC, cation transport regulator 1
chr6_-_51446850 0.10 ENSMUST00000069949.13
heterogeneous nuclear ribonucleoprotein A2/B1
chr13_-_76205115 0.10 ENSMUST00000056130.8
G protein-coupled receptor 150
chr2_-_152673032 0.10 ENSMUST00000128172.3
BCL2-like 1
chr8_-_120828211 0.10 ENSMUST00000034280.9
zinc finger, DHHC domain containing 7
chr5_-_123662175 0.10 ENSMUST00000200247.5
ENSMUST00000111586.8
ENSMUST00000031385.7
ENSMUST00000145152.8
ENSMUST00000111587.10
diablo, IAP-binding mitochondrial protein
chr5_+_139238089 0.09 ENSMUST00000130326.8
golgi to ER traffic protein 4
chr7_+_44221791 0.09 ENSMUST00000002274.10
napsin A aspartic peptidase
chr19_+_6451667 0.09 ENSMUST00000113471.3
ENSMUST00000113469.3
RAS, guanyl releasing protein 2
chr11_-_102120917 0.09 ENSMUST00000008999.12
histone deacetylase 5
chr6_-_51446752 0.09 ENSMUST00000204188.3
ENSMUST00000203220.3
ENSMUST00000114459.8
ENSMUST00000090002.10
heterogeneous nuclear ribonucleoprotein A2/B1
chr3_+_121746862 0.08 ENSMUST00000037958.14
ENSMUST00000196904.5
Rho GTPase activating protein 29
chr6_-_54941673 0.08 ENSMUST00000203837.2
nucleotide-binding oligomerization domain containing 1
chrX_+_35861851 0.08 ENSMUST00000073339.7
progesterone receptor membrane component 1
chr14_+_61375893 0.08 ENSMUST00000089394.10
sacsin
chr6_-_48818430 0.08 ENSMUST00000205147.3
transmembrane protein 176B
chr4_-_58499398 0.07 ENSMUST00000107570.2
lysophosphatidic acid receptor 1
chr12_-_81468705 0.07 ENSMUST00000085319.4
a disintegrin and metallopeptidase domain 4
chr2_+_153133326 0.07 ENSMUST00000028977.7
kinesin family member 3B
chr6_-_148732893 0.07 ENSMUST00000145960.2
importin 8
chr9_-_22218934 0.07 ENSMUST00000086278.7
ENSMUST00000215202.2
zinc finger protein 810
chr7_-_92523396 0.07 ENSMUST00000209074.2
ENSMUST00000208356.2
ENSMUST00000032877.11
DNA damage-induced apoptosis suppressor
chr5_-_38637474 0.07 ENSMUST00000143758.8
ENSMUST00000156272.8
solute carrier family 2 (facilitated glucose transporter), member 9
chr15_+_41310815 0.06 ENSMUST00000090096.11
ENSMUST00000110297.10
oxidation resistance 1
chr6_-_48818006 0.06 ENSMUST00000203229.3
transmembrane protein 176B
chr5_+_24631829 0.06 ENSMUST00000155598.8
solute carrier family 4 (anion exchanger), member 2
chr3_+_127584449 0.06 ENSMUST00000171621.3
TRAF-interacting protein with forkhead-associated domain
chr14_-_71003973 0.06 ENSMUST00000226448.2
ENSMUST00000022696.8
exportin 7
chr7_-_4909515 0.06 ENSMUST00000210663.2
predicted gene, 36210
chr10_+_80641067 0.06 ENSMUST00000036016.6
anti-Mullerian hormone
chr6_+_120643323 0.06 ENSMUST00000112686.8
CECR2, histone acetyl-lysine reader
chr5_-_137531471 0.06 ENSMUST00000143495.8
ENSMUST00000111020.8
ENSMUST00000111023.8
ENSMUST00000111038.8
guanine nucleotide binding protein (G protein), beta 2
erythropoietin
chr11_+_97340962 0.05 ENSMUST00000107601.8
Rho GTPase activating protein 23
chr2_+_181243109 0.05 ENSMUST00000136481.8
ENSMUST00000002529.7
pre-mRNA splicing factor 6
chr18_+_34910064 0.05 ENSMUST00000043775.9
ENSMUST00000224715.2
KDM3B lysine (K)-specific demethylase 3B
chr16_+_31918599 0.05 ENSMUST00000115168.9
centrosomal protein 19
chr8_-_23747057 0.05 ENSMUST00000051094.9
golgi autoantigen, golgin subfamily a, 7
chrX_+_149830166 0.05 ENSMUST00000026296.8
FYVE, RhoGEF and PH domain containing 1
chr5_+_101912939 0.05 ENSMUST00000031273.9
CDP-diacylglycerol synthase 1
chr11_+_121593219 0.05 ENSMUST00000036742.14
meteorin, glial cell differentiation regulator-like
chrX_-_8072714 0.04 ENSMUST00000089403.10
ENSMUST00000077595.12
ENSMUST00000089402.10
ENSMUST00000082320.12
porcupine O-acyltransferase
chr13_-_35211060 0.04 ENSMUST00000170538.8
ENSMUST00000163280.8
enoyl-Coenzyme A delta isomerase 2
chr3_+_129974531 0.04 ENSMUST00000080335.11
ENSMUST00000106353.2
collagen, type XXV, alpha 1
chr5_-_134343232 0.04 ENSMUST00000174867.8
general transcription factor II I
chr19_+_45003304 0.04 ENSMUST00000039016.14
leucine zipper, putative tumor suppressor 2
chr12_-_17061545 0.04 ENSMUST00000190691.2
RIKEN cDNA 2410004P03 gene
chr1_+_34498836 0.04 ENSMUST00000027302.14
ENSMUST00000190122.2
protein tyrosine phosphatase, non-receptor type 18
chr12_-_113945961 0.04 ENSMUST00000103466.2
immunoglobulin heavy variable 11-1
chr12_-_114419703 0.04 ENSMUST00000193397.2
immunoglobulin heavy variable V6-7
chr2_-_154411765 0.04 ENSMUST00000103145.11
E2F transcription factor 1
chr4_-_118477960 0.03 ENSMUST00000071972.11
cilia and flagella associated protein 57
chr4_-_117772163 0.03 ENSMUST00000036156.6
importin 13
chr19_-_6947112 0.03 ENSMUST00000025912.10
phospholipase C, beta 3
chr18_-_35841435 0.03 ENSMUST00000236738.2
ENSMUST00000237995.2
DnaJ heat shock protein family (Hsp40) member C18
chr7_-_126014027 0.03 ENSMUST00000032968.7
ENSMUST00000206325.2
CD19 antigen
chr8_+_3681127 0.03 ENSMUST00000159911.8
ENSMUST00000004745.9
syntaxin binding protein 2
chr5_+_136112817 0.03 ENSMUST00000100570.10
RAS p21 protein activator 4
chr5_+_102916637 0.03 ENSMUST00000112852.8
Rho GTPase activating protein 24
chr5_-_143255713 0.03 ENSMUST00000161448.8
zinc finger protein 316
chr7_+_45434755 0.03 ENSMUST00000233503.2
ENSMUST00000120005.10
ENSMUST00000211609.2
lemur tyrosine kinase 3
chr12_-_54909568 0.03 ENSMUST00000078124.8
cofilin 2, muscle
chr8_-_88686188 0.02 ENSMUST00000109655.9
zinc finger protein 423
chr11_+_101358990 0.02 ENSMUST00000001347.7
Rho family GTPase 2
chr2_+_164810139 0.02 ENSMUST00000202479.4
solute carrier family 12, member 5
chr11_-_11987391 0.02 ENSMUST00000093321.12
growth factor receptor bound protein 10
chr16_-_58850641 0.02 ENSMUST00000216415.2
ENSMUST00000206463.3
olfactory receptor 186
chr12_-_17061504 0.02 ENSMUST00000189479.2
RIKEN cDNA 2410004P03 gene
chr7_-_109322993 0.02 ENSMUST00000106735.9
ENSMUST00000033334.5
cDNA sequence BC051019
chr11_+_69909659 0.02 ENSMUST00000232002.2
ENSMUST00000134376.10
ENSMUST00000231221.2
discs large MAGUK scaffold protein 4
chr15_-_78428865 0.02 ENSMUST00000053239.4
somatostatin receptor 3
chr16_-_31918485 0.02 ENSMUST00000189013.8
ENSMUST00000155966.8
ENSMUST00000096109.11
ENSMUST00000232321.2
phosphatidylinositol glycan anchor biosynthesis, class X
chr6_-_4747066 0.02 ENSMUST00000090686.11
ENSMUST00000133306.8
sarcoglycan, epsilon
chr2_-_89361831 0.02 ENSMUST00000144885.3
olfactory receptor 1243
chr12_-_75224099 0.02 ENSMUST00000042299.4
potassium voltage-gated channel, subfamily H (eag-related), member 5
chr19_+_16416664 0.02 ENSMUST00000237350.2
guanine nucleotide binding protein, alpha 14
chr7_-_114235506 0.01 ENSMUST00000205714.2
ENSMUST00000206853.2
ENSMUST00000205933.2
ENSMUST00000206156.2
ENSMUST00000032907.9
ENSMUST00000032906.11
calcitonin/calcitonin-related polypeptide, alpha
chr3_-_66888474 0.01 ENSMUST00000162439.8
ENSMUST00000162098.9
short stature homeobox 2
chr7_+_141755098 0.01 ENSMUST00000187512.2
ENSMUST00000084414.6
keratin associated protein 5-3
chr3_+_87855973 0.01 ENSMUST00000005019.6
cellular retinoic acid binding protein II
chr5_+_95021656 0.01 ENSMUST00000180076.2
predicted gene 3183
chr13_+_22512081 0.01 ENSMUST00000091734.2
vomeronasal 1 receptor 197
chr11_+_73819052 0.01 ENSMUST00000205791.2
olfactory receptor 396, pseudogene 1
chr1_+_135764092 0.01 ENSMUST00000188028.7
ENSMUST00000178204.8
ENSMUST00000190451.7
ENSMUST00000189732.7
ENSMUST00000189355.7
troponin T2, cardiac
chr6_-_90050000 0.01 ENSMUST00000071865.2
vomeronasal 1, receptor 49
chr19_-_58442866 0.01 ENSMUST00000169850.8
glial cell line derived neurotrophic factor family receptor alpha 1
chr1_-_131204422 0.01 ENSMUST00000159195.2
inhibitor of kappaB kinase epsilon
chr4_+_155819257 0.01 ENSMUST00000147721.8
ENSMUST00000127188.3
transmembrane protein 240
chr7_-_141744126 0.01 ENSMUST00000210290.2
ENSMUST00000084415.5
predicted gene 10153
chr6_+_21215472 0.01 ENSMUST00000081542.6
potassium voltage-gated channel, Shal-related family, member 2
chr15_+_66763169 0.01 ENSMUST00000005255.9
cellular communication network factor 4
chr7_-_23508625 0.01 ENSMUST00000166141.2
vomeronasal 1 receptor 175
chr11_+_74174562 0.01 ENSMUST00000214048.3
ENSMUST00000143976.4
ENSMUST00000205790.2
ENSMUST00000206659.2
olfactory receptor 59
chr11_+_76795346 0.01 ENSMUST00000072633.4
transmembrane and immunoglobulin domain containing 1
chrX_+_8137372 0.01 ENSMUST00000127103.8
ENSMUST00000115591.8
solute carrier family 38, member 5
chr3_+_100732768 0.01 ENSMUST00000054791.9
V-set domain containing T cell activation inhibitor 1
chr5_-_38316296 0.01 ENSMUST00000201415.4
neuron specific gene family member 1
chr7_-_4999042 0.01 ENSMUST00000162502.2
zinc finger protein 579
chr7_-_126303947 0.01 ENSMUST00000032949.14
coronin, actin binding protein 1A
chr12_-_114117264 0.01 ENSMUST00000103461.5
immunoglobulin heavy variable 7-3
chr17_-_34337446 0.01 ENSMUST00000095347.13
bromodomain containing 2

Network of associatons between targets according to the STRING database.

First level regulatory network of Glis2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0002148 hypochlorous acid metabolic process(GO:0002148) hypochlorous acid biosynthetic process(GO:0002149)
0.2 0.6 GO:0046072 dTDP biosynthetic process(GO:0006233) dTDP metabolic process(GO:0046072)
0.2 0.5 GO:0060160 negative regulation of dopamine receptor signaling pathway(GO:0060160)
0.1 0.4 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973)
0.1 0.5 GO:0090118 regulation of phosphatidylcholine catabolic process(GO:0010899) receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport(GO:0090118) positive regulation of lysosomal protein catabolic process(GO:1905167)
0.1 0.8 GO:0061502 uropod organization(GO:0032796) early endosome to recycling endosome transport(GO:0061502)
0.1 0.5 GO:0097473 cellular response to light intensity(GO:0071484) cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473)
0.1 0.6 GO:0006177 GMP biosynthetic process(GO:0006177)
0.1 0.5 GO:0001561 fatty acid alpha-oxidation(GO:0001561)
0.1 0.3 GO:0046898 response to cycloheximide(GO:0046898)
0.1 0.5 GO:0044828 negative regulation by host of viral genome replication(GO:0044828)
0.1 0.2 GO:1990428 miRNA transport(GO:1990428)
0.1 0.2 GO:0046391 5-phosphoribose 1-diphosphate biosynthetic process(GO:0006015) 5-phosphoribose 1-diphosphate metabolic process(GO:0046391)
0.1 0.1 GO:0006235 dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212) dTTP metabolic process(GO:0046075)
0.1 0.2 GO:0034201 response to oleic acid(GO:0034201)
0.0 0.2 GO:1901315 negative regulation of histone ubiquitination(GO:0033183) regulation of histone H2A K63-linked ubiquitination(GO:1901314) negative regulation of histone H2A K63-linked ubiquitination(GO:1901315)
0.0 0.2 GO:0002317 plasma cell differentiation(GO:0002317)
0.0 0.3 GO:0097428 protein maturation by iron-sulfur cluster transfer(GO:0097428)
0.0 0.4 GO:1902474 positive regulation of protein localization to synapse(GO:1902474)
0.0 0.4 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.1 GO:1902269 positive regulation of polyamine transmembrane transport(GO:1902269)
0.0 0.1 GO:0000454 snoRNA guided rRNA pseudouridine synthesis(GO:0000454)
0.0 0.1 GO:0097155 fasciculation of sensory neuron axon(GO:0097155)
0.0 0.2 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.3 GO:0060011 Sertoli cell proliferation(GO:0060011)
0.0 0.2 GO:0061198 maintenance of chromatin silencing(GO:0006344) fungiform papilla formation(GO:0061198)
0.0 0.2 GO:0036265 RNA (guanine-N7)-methylation(GO:0036265)
0.0 0.2 GO:0060023 soft palate development(GO:0060023)
0.0 0.2 GO:0006004 fucose metabolic process(GO:0006004)
0.0 0.2 GO:0009249 protein lipoylation(GO:0009249)
0.0 0.1 GO:0048162 preantral ovarian follicle growth(GO:0001546) multi-layer follicle stage(GO:0048162)
0.0 0.1 GO:1902219 negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress(GO:1902219)
0.0 0.1 GO:1904565 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.0 0.3 GO:0043568 positive regulation of insulin-like growth factor receptor signaling pathway(GO:0043568)
0.0 0.1 GO:0006362 transcription elongation from RNA polymerase I promoter(GO:0006362)
0.0 0.5 GO:0015991 ATP hydrolysis coupled proton transport(GO:0015991)
0.0 0.2 GO:0070493 thrombin receptor signaling pathway(GO:0070493)
0.0 0.1 GO:2000601 positive regulation of Arp2/3 complex-mediated actin nucleation(GO:2000601)
0.0 0.8 GO:0006406 mRNA export from nucleus(GO:0006406) mRNA-containing ribonucleoprotein complex export from nucleus(GO:0071427)
0.0 0.1 GO:0036506 maintenance of unfolded protein(GO:0036506) maintenance of unfolded protein involved in ERAD pathway(GO:1904378)
0.0 0.5 GO:0007094 mitotic spindle assembly checkpoint(GO:0007094)
0.0 0.1 GO:0008635 activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c(GO:0008635)
0.0 0.3 GO:0006744 ubiquinone biosynthetic process(GO:0006744)
0.0 0.2 GO:0009083 branched-chain amino acid catabolic process(GO:0009083)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.5 GO:1990666 PCSK9-LDLR complex(GO:1990666)
0.1 0.2 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.0 0.2 GO:0031084 BLOC-2 complex(GO:0031084)
0.0 0.7 GO:0005766 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.0 0.5 GO:0097136 Bcl-2 family protein complex(GO:0097136)
0.0 0.5 GO:0032591 dendritic spine membrane(GO:0032591)
0.0 0.3 GO:0005827 polar microtubule(GO:0005827)
0.0 0.1 GO:0090661 box H/ACA telomerase RNP complex(GO:0090661)
0.0 0.2 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.0 0.5 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 0.9 GO:0032426 stereocilium tip(GO:0032426)
0.0 0.5 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.4 GO:0031080 nuclear pore outer ring(GO:0031080)
0.0 0.3 GO:0034709 methylosome(GO:0034709)
0.0 0.1 GO:0016939 kinesin II complex(GO:0016939)
0.0 0.2 GO:0090571 RNA polymerase II transcription repressor complex(GO:0090571)
0.0 0.1 GO:0090537 CERF complex(GO:0090537)
0.0 0.1 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.3 GO:0002178 palmitoyltransferase complex(GO:0002178)
0.0 0.2 GO:0005675 holo TFIIH complex(GO:0005675)
0.0 0.2 GO:0005869 dynactin complex(GO:0005869)
0.0 0.2 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.0 0.8 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.1 GO:0033116 endoplasmic reticulum-Golgi intermediate compartment membrane(GO:0033116)
0.0 0.1 GO:0072379 BAT3 complex(GO:0071818) ER membrane insertion complex(GO:0072379)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 GO:0004798 thymidylate kinase activity(GO:0004798)
0.2 0.5 GO:0033149 FFAT motif binding(GO:0033149)
0.1 0.6 GO:0003938 IMP dehydrogenase activity(GO:0003938)
0.1 0.5 GO:0031750 D3 dopamine receptor binding(GO:0031750)
0.1 0.2 GO:0015928 alpha-L-fucosidase activity(GO:0004560) fucosidase activity(GO:0015928)
0.1 0.2 GO:0031177 phosphopantetheine binding(GO:0031177)
0.1 0.2 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.1 0.5 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.1 0.2 GO:0015057 thrombin receptor activity(GO:0015057)
0.1 0.3 GO:0004430 1-phosphatidylinositol 4-kinase activity(GO:0004430)
0.1 0.2 GO:0035851 Krueppel-associated box domain binding(GO:0035851)
0.1 0.2 GO:0008176 tRNA (guanine-N7-)-methyltransferase activity(GO:0008176)
0.0 0.3 GO:0008384 IkappaB kinase activity(GO:0008384)
0.0 0.5 GO:0030976 thiamine pyrophosphate binding(GO:0030976)
0.0 0.2 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.0 0.2 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.0 0.8 GO:0032036 myosin heavy chain binding(GO:0032036)
0.0 0.3 GO:0031995 insulin-like growth factor II binding(GO:0031995)
0.0 0.1 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.0 0.3 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.2 GO:0047760 butyrate-CoA ligase activity(GO:0047760)
0.0 0.1 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.0 0.1 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.0 0.2 GO:0004300 enoyl-CoA hydratase activity(GO:0004300)
0.0 0.4 GO:0070402 NADPH binding(GO:0070402)
0.0 0.1 GO:0001226 RNA polymerase II transcription corepressor binding(GO:0001226)
0.0 0.1 GO:0003839 gamma-glutamylcyclotransferase activity(GO:0003839)
0.0 0.2 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 0.9 GO:0005246 calcium channel regulator activity(GO:0005246)
0.0 0.5 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.0 GO:0004605 phosphatidate cytidylyltransferase activity(GO:0004605)
0.0 0.0 GO:1990698 palmitoleoyltransferase activity(GO:1990698)
0.0 0.0 GO:0004165 dodecenoyl-CoA delta-isomerase activity(GO:0004165)
0.0 0.2 GO:0051400 BH domain binding(GO:0051400)
0.0 0.4 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 0.4 GO:0005487 nucleocytoplasmic transporter activity(GO:0005487)
0.0 0.4 GO:0019707 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)
0.0 0.1 GO:0035727 lysophosphatidic acid binding(GO:0035727) lysophosphatidic acid receptor activity(GO:0070915)
0.0 0.0 GO:0030348 syntaxin-3 binding(GO:0030348)
0.0 0.7 GO:0004601 peroxidase activity(GO:0004601)
0.0 0.4 GO:0042165 neurotransmitter binding(GO:0042165)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 SA TRKA RECEPTOR The TrkA receptor binds nerve growth factor to activate MAP kinase pathways and promote cell growth.
0.0 0.7 PID IL23 PATHWAY IL23-mediated signaling events
0.0 0.3 SA PROGRAMMED CELL DEATH Programmed cell death, or apoptosis, eliminates damaged or unneeded cells.
0.0 0.2 PID THROMBIN PAR4 PATHWAY PAR4-mediated thrombin signaling events
0.0 0.3 PID WNT SIGNALING PATHWAY Wnt signaling network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.5 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.6 REACTOME PURINE RIBONUCLEOSIDE MONOPHOSPHATE BIOSYNTHESIS Genes involved in Purine ribonucleoside monophosphate biosynthesis
0.0 1.2 REACTOME G BETA GAMMA SIGNALLING THROUGH PLC BETA Genes involved in G beta:gamma signalling through PLC beta
0.0 0.4 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.5 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.0 0.6 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.3 REACTOME REGULATION OF INSULIN LIKE GROWTH FACTOR IGF ACTIVITY BY INSULIN LIKE GROWTH FACTOR BINDING PROTEINS IGFBPS Genes involved in Regulation of Insulin-like Growth Factor (IGF) Activity by Insulin-like Growth Factor Binding Proteins (IGFBPs)
0.0 0.2 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 0.3 REACTOME ACTIVATION OF IRF3 IRF7 MEDIATED BY TBK1 IKK EPSILON Genes involved in Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon
0.0 0.4 REACTOME RNA POL I TRANSCRIPTION TERMINATION Genes involved in RNA Polymerase I Transcription Termination
0.0 0.5 REACTOME PEROXISOMAL LIPID METABOLISM Genes involved in Peroxisomal lipid metabolism
0.0 0.3 REACTOME SYNTHESIS OF PIPS AT THE GOLGI MEMBRANE Genes involved in Synthesis of PIPs at the Golgi membrane
0.0 0.2 REACTOME THROMBIN SIGNALLING THROUGH PROTEINASE ACTIVATED RECEPTORS PARS Genes involved in Thrombin signalling through proteinase activated receptors (PARs)