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avrg: GFI1 WT vs 36n/n vs KD

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Results for Hivep1

Z-value: 1.25

Motif logo

Transcription factors associated with Hivep1

Gene Symbol Gene ID Gene Info
ENSMUSG00000021366.9 human immunodeficiency virus type I enhancer binding protein 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Hivep1mm39_v1_chr13_+_42205790_42205880-0.247.0e-01Click!

Activity profile of Hivep1 motif

Sorted Z-values of Hivep1 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr6_-_129252396 2.22 ENSMUST00000032259.6
CD69 antigen
chr17_+_35598583 1.41 ENSMUST00000081435.5
histocompatibility 2, Q region locus 4
chr6_-_129252323 1.19 ENSMUST00000204411.2
CD69 antigen
chr17_-_34219225 1.01 ENSMUST00000238098.2
ENSMUST00000087189.7
ENSMUST00000173075.3
ENSMUST00000172912.8
ENSMUST00000236740.2
ENSMUST00000025181.18
histocompatibility 2, K1, K region
chr14_-_55828511 0.91 ENSMUST00000161807.8
ENSMUST00000111378.10
ENSMUST00000159687.2
proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
chr12_-_55539372 0.82 ENSMUST00000021413.9
nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, alpha
chr5_-_138169253 0.79 ENSMUST00000139983.8
minichromosome maintenance complex component 7
chr5_-_138169509 0.72 ENSMUST00000153867.8
minichromosome maintenance complex component 7
chr17_+_35780977 0.66 ENSMUST00000174525.8
ENSMUST00000068291.7
histocompatibility 2, Q region locus 10
chr6_-_83030759 0.60 ENSMUST00000134606.8
HtrA serine peptidase 2
chr5_-_92496730 0.58 ENSMUST00000038816.13
ENSMUST00000118006.3
chemokine (C-X-C motif) ligand 10
chr11_+_101207743 0.58 ENSMUST00000151385.2
proteaseome (prosome, macropain) activator subunit 3 (PA28 gamma, Ki)
chr17_+_35482063 0.54 ENSMUST00000172503.3
histocompatibility 2, D region locus 1
chr18_+_84106796 0.51 ENSMUST00000235383.2
zinc binding alcohol dehydrogenase, domain containing 2
chr18_+_84106188 0.50 ENSMUST00000060223.4
zinc binding alcohol dehydrogenase, domain containing 2
chr7_-_46365108 0.50 ENSMUST00000006956.9
ENSMUST00000210913.2
serum amyloid A 3
chr17_-_28736483 0.50 ENSMUST00000114792.8
ENSMUST00000177939.8
FK506 binding protein 5
chr4_-_40239778 0.50 ENSMUST00000037907.13
DEAD/H box helicase 58
chr7_-_30855295 0.44 ENSMUST00000186723.3
GRAM domain containing 1A
chr17_+_35481702 0.43 ENSMUST00000172785.8
histocompatibility 2, D region locus 1
chr4_-_43031370 0.43 ENSMUST00000138030.2
ENSMUST00000136326.8
stomatin (Epb7.2)-like 2
chr17_-_34109513 0.43 ENSMUST00000173386.2
ENSMUST00000114361.9
ENSMUST00000173492.9
kinesin family member C1
chr17_+_75024727 0.43 ENSMUST00000024882.8
ENSMUST00000234751.2
ENSMUST00000234568.2
tetratricopeptide repeat domain 27
chr4_+_123176570 0.42 ENSMUST00000106243.8
ENSMUST00000106241.8
ENSMUST00000080178.13
poly(A) binding protein, cytoplasmic 4
chr3_+_127584251 0.40 ENSMUST00000164447.3
TRAF-interacting protein with forkhead-associated domain
chr12_-_40298072 0.39 ENSMUST00000169926.8
interferon-related developmental regulator 1
chr3_-_88858465 0.39 ENSMUST00000173135.8
death associated protein 3
chr3_+_115681788 0.38 ENSMUST00000196804.5
ENSMUST00000106505.8
ENSMUST00000043342.10
diphthamide biosynthesis 5
chr15_+_76594810 0.37 ENSMUST00000136840.8
ENSMUST00000127208.8
ENSMUST00000036423.15
ENSMUST00000137649.8
ENSMUST00000155225.2
ENSMUST00000155735.2
leucine rich repeat containing 14
chr11_+_70548022 0.35 ENSMUST00000157027.8
ENSMUST00000072841.12
ENSMUST00000108548.8
ENSMUST00000126241.8
enolase 3, beta muscle
chr14_+_55798362 0.34 ENSMUST00000072530.11
ENSMUST00000128490.9
DDB1 and CUL4 associated factor 11
chr5_-_138169476 0.34 ENSMUST00000147920.2
minichromosome maintenance complex component 7
chr11_+_97697328 0.34 ENSMUST00000153520.3
LIM and SH3 protein 1
chr11_-_5492175 0.33 ENSMUST00000020776.5
coiled-coil domain containing 117
chr17_-_35081456 0.33 ENSMUST00000025229.11
ENSMUST00000176203.9
ENSMUST00000128767.8
complement factor B
chr15_+_102379503 0.32 ENSMUST00000229222.2
poly(rC) binding protein 2
chr3_-_88858402 0.31 ENSMUST00000173021.8
death associated protein 3
chr14_+_52222283 0.31 ENSMUST00000093813.12
ENSMUST00000100639.11
ENSMUST00000182909.8
ENSMUST00000182760.8
ENSMUST00000182061.8
ENSMUST00000182193.2
Rho guanine nucleotide exchange factor (GEF) 40
chr19_+_24853039 0.29 ENSMUST00000073080.7
predicted gene 10053
chr2_-_93292257 0.29 ENSMUST00000150508.8
CD82 antigen
chr4_-_40239700 0.28 ENSMUST00000142055.2
DEAD/H box helicase 58
chr1_+_161796854 0.28 ENSMUST00000160881.2
ENSMUST00000159648.2
phosphatidylinositol glycan anchor biosynthesis, class C
chr11_+_60590584 0.28 ENSMUST00000108719.4
LLGL1 scribble cell polarity complex component
chr12_-_113912416 0.27 ENSMUST00000103464.3
immunoglobulin heavy variable 4-1
chr14_+_55798517 0.27 ENSMUST00000117701.8
DDB1 and CUL4 associated factor 11
chr7_+_27305222 0.27 ENSMUST00000143499.8
ENSMUST00000108343.8
thymoma viral proto-oncogene 2
chr9_+_95739650 0.26 ENSMUST00000034980.9
ataxia telangiectasia and Rad3 related
chr9_+_5308828 0.26 ENSMUST00000162846.8
ENSMUST00000027012.14
caspase 4, apoptosis-related cysteine peptidase
chr3_-_107667499 0.26 ENSMUST00000153114.2
ENSMUST00000118593.8
ENSMUST00000120243.8
colony stimulating factor 1 (macrophage)
chr9_+_95739747 0.26 ENSMUST00000215311.2
ataxia telangiectasia and Rad3 related
chr3_-_65865656 0.24 ENSMUST00000029416.14
cyclin L1
chr7_+_27305271 0.23 ENSMUST00000051356.12
thymoma viral proto-oncogene 2
chr2_-_26917921 0.23 ENSMUST00000102890.11
ENSMUST00000153388.2
ENSMUST00000045702.6
solute carrier family 2 (facilitated glucose transporter), member 6
chr18_-_34784746 0.23 ENSMUST00000025228.12
ENSMUST00000133181.2
CDC23 cell division cycle 23
chr17_+_27136065 0.22 ENSMUST00000078961.6
kinesin family member C5B
chr4_+_151012375 0.22 ENSMUST00000139826.8
ENSMUST00000116257.8
tumor necrosis factor receptor superfamily, member 9
chr7_-_125799585 0.22 ENSMUST00000163959.2
exportin 6
chr11_-_97913420 0.22 ENSMUST00000103144.10
ENSMUST00000017552.13
ENSMUST00000092736.11
ENSMUST00000107562.2
calcium channel, voltage-dependent, beta 1 subunit
chr7_-_19363280 0.21 ENSMUST00000094762.10
ENSMUST00000049912.15
ENSMUST00000098754.5
avian reticuloendotheliosis viral (v-rel) oncogene related B
chr5_-_36771074 0.21 ENSMUST00000132383.6
ENSMUST00000174019.2
DNA segment, Chr 5, ERATO Doi 579, expressed
predicted gene 42936
chr4_+_126156118 0.20 ENSMUST00000030660.9
trafficking protein particle complex 3
chr12_+_111132779 0.20 ENSMUST00000117269.8
TNF receptor-associated factor 3
chr2_-_126341757 0.20 ENSMUST00000040128.12
ATPase, class I, type 8B, member 4
chr16_-_18052937 0.19 ENSMUST00000076957.7
zinc finger, DHHC domain containing 8
chr2_-_5068807 0.19 ENSMUST00000114996.8
optineurin
chr13_-_100382831 0.19 ENSMUST00000049789.3
NLR family, apoptosis inhibitory protein 5
chr7_+_79836581 0.18 ENSMUST00000032754.9
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
chr17_+_35413415 0.18 ENSMUST00000025262.6
ENSMUST00000173600.2
lymphotoxin B
chr2_+_163535925 0.18 ENSMUST00000109400.3
protein kinase inhibitor, gamma
chr17_+_71511642 0.17 ENSMUST00000126681.8
lipin 2
chr16_-_3725515 0.17 ENSMUST00000177221.2
ENSMUST00000177323.8
RIKEN cDNA 1700037C18 gene
chr7_+_99184645 0.17 ENSMUST00000098266.9
ENSMUST00000179755.8
arrestin, beta 1
chr16_-_52272828 0.16 ENSMUST00000170035.8
ENSMUST00000164728.8
ENSMUST00000168071.2
activated leukocyte cell adhesion molecule
chr9_-_57672124 0.16 ENSMUST00000215158.2
CDC-like kinase 3
chr12_+_111132847 0.16 ENSMUST00000021706.11
TNF receptor-associated factor 3
chr1_-_36312482 0.16 ENSMUST00000056946.8
neuralized E3 ubiquitin protein ligase 3
chr1_+_55276336 0.16 ENSMUST00000061334.10
methionine-tRNA synthetase 2 (mitochondrial)
chr9_-_44646487 0.16 ENSMUST00000034611.15
pleckstrin homology like domain, family B, member 1
chr11_-_70128712 0.16 ENSMUST00000108577.8
ENSMUST00000108579.8
ENSMUST00000021181.13
ENSMUST00000108578.9
ENSMUST00000102569.10
RIKEN cDNA 0610010K14 gene
chr9_-_78389006 0.14 ENSMUST00000042235.15
eukaryotic translation elongation factor 1 alpha 1
chr2_+_118730823 0.14 ENSMUST00000151162.2
bromo adjacent homology domain containing 1
chr11_+_94102255 0.14 ENSMUST00000041589.6
transducer of ErbB-2.1
chr15_+_102379621 0.14 ENSMUST00000229918.2
poly(rC) binding protein 2
chr14_+_55797934 0.14 ENSMUST00000121622.8
ENSMUST00000143431.2
ENSMUST00000150481.8
DDB1 and CUL4 associated factor 11
chr17_-_84495364 0.13 ENSMUST00000060366.7
zinc finger protein 36, C3H type-like 2
chr2_-_5068743 0.13 ENSMUST00000027986.5
optineurin
chr6_+_83034825 0.12 ENSMUST00000077502.5
DEAQ RNA-dependent ATPase
chr11_-_101193032 0.12 ENSMUST00000140706.8
ENSMUST00000170502.2
ENSMUST00000172233.8
beclin 1, autophagy related
chr11_+_78237492 0.11 ENSMUST00000100755.4
unc-119 lipid binding chaperone
chrX_-_133501677 0.10 ENSMUST00000239113.2
galactosidase, alpha
chr8_+_61085890 0.10 ENSMUST00000160719.8
microfibrillar-associated protein 3-like
chr5_-_144902598 0.10 ENSMUST00000110677.8
ENSMUST00000085684.11
ENSMUST00000100461.7
SMAD specific E3 ubiquitin protein ligase 1
chr11_+_100751151 0.10 ENSMUST00000138083.8
signal transducer and activator of transcription 5A
chr3_+_127584449 0.10 ENSMUST00000171621.3
TRAF-interacting protein with forkhead-associated domain
chr13_+_43938251 0.10 ENSMUST00000015540.4
CD83 antigen
chr19_-_6919755 0.09 ENSMUST00000099782.10
G protein-coupled receptor 137
chr5_-_98178834 0.09 ENSMUST00000199088.2
anthrax toxin receptor 2
chr11_-_93846453 0.09 ENSMUST00000072566.5
NME/NM23 nucleoside diphosphate kinase 2
chr7_+_30121776 0.09 ENSMUST00000108175.8
nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, delta
chr4_-_133695264 0.09 ENSMUST00000102553.11
high mobility group nucleosomal binding domain 2
chr1_-_172418058 0.09 ENSMUST00000065679.8
SLAM family member 8
chr4_+_155646807 0.09 ENSMUST00000030939.14
NAD kinase
chrX_-_133501874 0.08 ENSMUST00000033621.8
galactosidase, alpha
chr6_+_55313409 0.08 ENSMUST00000004774.4
aquaporin 1
chr4_-_82423985 0.08 ENSMUST00000107245.9
ENSMUST00000107246.2
nuclear factor I/B
chr17_+_45088030 0.08 ENSMUST00000050630.14
SPT3, SAGA and STAGA complex component
chr1_+_192984278 0.08 ENSMUST00000016315.16
laminin, beta 3
chr11_+_78079562 0.08 ENSMUST00000108322.9
RAB34, member RAS oncogene family
chr6_-_8778439 0.08 ENSMUST00000115520.8
ENSMUST00000038403.12
ENSMUST00000115518.8
islet cell autoantigen 1
chr12_+_85733415 0.08 ENSMUST00000040536.6
basic leucine zipper transcription factor, ATF-like
chr4_-_120672900 0.08 ENSMUST00000120779.8
nuclear transcription factor-Y gamma
chr1_+_161796748 0.08 ENSMUST00000111594.3
ENSMUST00000028021.7
ENSMUST00000193784.2
ENSMUST00000161826.2
phosphatidylinositol glycan anchor biosynthesis, class C
predicted gene, 38304
chr11_+_78079631 0.07 ENSMUST00000056241.12
ENSMUST00000207728.2
RAB34, member RAS oncogene family
chr17_-_36012932 0.07 ENSMUST00000166980.9
ENSMUST00000145900.8
discoidin domain receptor family, member 1
chr5_-_98178811 0.07 ENSMUST00000031281.14
anthrax toxin receptor 2
chr17_+_45866618 0.07 ENSMUST00000024742.9
ENSMUST00000233929.2
nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, epsilon
chr5_+_30437579 0.07 ENSMUST00000145167.9
selenoprotein I
chr13_-_19521337 0.06 ENSMUST00000103563.3
T cell receptor gamma variable 2
chr7_-_125799644 0.06 ENSMUST00000168189.8
exportin 6
chr12_-_113823290 0.06 ENSMUST00000103459.5
immunoglobulin heavy variable 5-17
chr15_+_78129040 0.06 ENSMUST00000133618.3
neutrophil cytosolic factor 4
chr14_+_51045298 0.06 ENSMUST00000036126.7
poly (ADP-ribose) polymerase family, member 2
chr3_+_96508400 0.06 ENSMUST00000062058.5
Lix1-like
chr17_+_56312672 0.06 ENSMUST00000133998.8
MPN domain containing
chr6_-_48818006 0.05 ENSMUST00000203229.3
transmembrane protein 176B
chr8_-_47866869 0.05 ENSMUST00000211882.2
storkhead box 2
chr1_+_186947934 0.05 ENSMUST00000160471.8
G patch domain containing 2
chr12_-_113945961 0.05 ENSMUST00000103466.2
immunoglobulin heavy variable 11-1
chr7_+_30121147 0.05 ENSMUST00000108176.9
nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, delta
chr6_-_8778106 0.05 ENSMUST00000151758.2
ENSMUST00000115519.8
ENSMUST00000153390.8
islet cell autoantigen 1
chr12_-_28685849 0.04 ENSMUST00000221871.2
ribosomal protein S7
chr11_+_75546989 0.04 ENSMUST00000136935.2
myosin IC
chr5_-_92231517 0.04 ENSMUST00000202258.4
ENSMUST00000113127.7
GTPase activating protein (SH3 domain) binding protein 2
chr7_+_127864847 0.04 ENSMUST00000118169.8
ENSMUST00000206909.2
ENSMUST00000142841.8
solute carrier family 5 (sodium/glucose cotransporter), member 2
chr7_-_125799570 0.04 ENSMUST00000009344.16
exportin 6
chr11_-_70128678 0.04 ENSMUST00000108575.9
RIKEN cDNA 0610010K14 gene
chr11_+_101066867 0.04 ENSMUST00000103109.4
contactin associated protein-like 1
chr6_+_41090484 0.03 ENSMUST00000103267.3
T cell receptor beta, variable 12-1
chr12_+_98886826 0.03 ENSMUST00000085109.10
ENSMUST00000079146.13
tetratricopeptide repeat domain 8
chr12_-_113561594 0.03 ENSMUST00000103444.3
immunoglobulin heavy variable 5-4
chr7_+_19222972 0.03 ENSMUST00000011407.8
exocyst complex component 3-like 2
chr11_+_75546671 0.03 ENSMUST00000108431.3
myosin IC
chr8_+_61085853 0.02 ENSMUST00000161421.2
microfibrillar-associated protein 3-like
chr13_-_113800172 0.02 ENSMUST00000054650.5
heat shock protein 3
chr16_+_45430743 0.02 ENSMUST00000161347.9
ENSMUST00000023339.5
germinal center associated, signaling and motility
chr9_-_70842090 0.02 ENSMUST00000034731.10
lipase, hepatic
chr7_-_90106375 0.02 ENSMUST00000032844.7
transmembrane protein 126A
chr3_+_20039775 0.02 ENSMUST00000172860.2
ceruloplasmin
chr11_+_69920542 0.02 ENSMUST00000232266.2
ENSMUST00000132597.5
discs large MAGUK scaffold protein 4
chr5_+_90708962 0.02 ENSMUST00000094615.8
ENSMUST00000200765.2
albumin superfamily member 1
chr16_-_58930996 0.02 ENSMUST00000076262.4
olfactory receptor 193
chr18_+_37822865 0.02 ENSMUST00000195112.2
protocadherin gamma subfamily B, 2
chr14_+_54713557 0.01 ENSMUST00000164766.8
rad and gem related GTP binding protein 2
chr15_+_78128990 0.01 ENSMUST00000096357.12
neutrophil cytosolic factor 4
chr16_-_26786995 0.01 ENSMUST00000231969.2
geminin coiled-coil domain containing
chr14_+_53562089 0.01 ENSMUST00000178100.3
T cell receptor alpha variable 7N-6
chrX_-_8072714 0.01 ENSMUST00000089403.10
ENSMUST00000077595.12
ENSMUST00000089402.10
ENSMUST00000082320.12
porcupine O-acyltransferase
chr14_-_8551429 0.01 ENSMUST00000112652.9
predicted gene 11100
chr19_+_34268053 0.01 ENSMUST00000025691.13
Fas (TNF receptor superfamily member 6)
chrX_-_58612709 0.01 ENSMUST00000124402.2
fibroblast growth factor 13
chr6_-_21851827 0.01 ENSMUST00000202353.2
ENSMUST00000134635.2
ENSMUST00000123116.8
ENSMUST00000120965.8
ENSMUST00000143531.2
tetraspanin 12
chr6_-_136148820 0.01 ENSMUST00000188999.3
glutamate receptor, ionotropic, NMDA2B (epsilon 2)
chr7_+_27353331 0.01 ENSMUST00000008088.9
tetratricopeptide repeat domain 9B
chr14_-_34225281 0.01 ENSMUST00000171343.9
bone morphogenetic protein receptor, type 1A
chr1_-_13062873 0.01 ENSMUST00000188454.7
solute carrier organic anion transporter family, member 5A1
chr18_-_39062201 0.01 ENSMUST00000134864.2
fibroblast growth factor 1
chr10_+_129603367 0.01 ENSMUST00000060636.2
olfactory receptor 808
chr6_-_21852508 0.00 ENSMUST00000031678.10
tetraspanin 12
chr7_-_99276310 0.00 ENSMUST00000178124.3
trophoblast glycoprotein-like
chr7_-_103778992 0.00 ENSMUST00000053743.6
ubiquilin 5
chr2_-_103133524 0.00 ENSMUST00000090475.10
ets homologous factor
chr14_+_53007210 0.00 ENSMUST00000178768.4
T cell receptor alpha variable 7D-4
chr7_-_103721076 0.00 ENSMUST00000213184.2
ENSMUST00000213991.2
olfactory receptor 644
chr2_-_103133503 0.00 ENSMUST00000111176.9
ets homologous factor
chr6_+_89691185 0.00 ENSMUST00000075158.2
vomeronasal 1 receptor 40
chr14_+_53628092 0.00 ENSMUST00000103636.4
T cell receptor alpha variable 7-2
chr12_+_36364136 0.00 ENSMUST00000041407.7
sclerostin domain containing 1
chr7_-_108493612 0.00 ENSMUST00000202706.2
ENSMUST00000084752.2
olfactory receptor 519
chr7_-_104812698 0.00 ENSMUST00000215552.2
ENSMUST00000215744.2
ENSMUST00000217136.2
olfactory receptor 684
chr9_-_70841881 0.00 ENSMUST00000214995.2
lipase, hepatic
chr4_-_57916283 0.00 ENSMUST00000063816.6
RIKEN cDNA D630039A03 gene
chr6_-_83513222 0.00 ENSMUST00000075161.12
actin, gamma 2, smooth muscle, enteric
chr1_-_176041498 0.00 ENSMUST00000111167.2
phospholipase D family, member 5
chr18_-_39062514 0.00 ENSMUST00000235922.2
fibroblast growth factor 1
chr16_-_58747023 0.00 ENSMUST00000205742.2
olfactory receptor 181
chr14_+_53698556 0.00 ENSMUST00000181728.3
T cell receptor alpha variable 7-4

Network of associatons between targets according to the STRING database.

First level regulatory network of Hivep1

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 2.0 GO:0002484 antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway(GO:0002484) antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent(GO:0002485)
0.2 0.6 GO:1904924 negative regulation of mitophagy in response to mitochondrial depolarization(GO:1904924)
0.2 0.8 GO:0009597 detection of virus(GO:0009597)
0.2 1.8 GO:0006268 DNA unwinding involved in DNA replication(GO:0006268)
0.1 0.6 GO:1901740 negative regulation of myoblast fusion(GO:1901740)
0.1 0.5 GO:1904884 telomerase catalytic core complex assembly(GO:1904868) regulation of telomerase catalytic core complex assembly(GO:1904882) positive regulation of telomerase catalytic core complex assembly(GO:1904884)
0.1 0.4 GO:1901860 positive regulation of mitochondrial DNA metabolic process(GO:1901860)
0.1 0.4 GO:0072385 minus-end-directed organelle transport along microtubule(GO:0072385)
0.1 0.7 GO:0070427 nucleotide-binding oligomerization domain containing 1 signaling pathway(GO:0070427)
0.1 0.3 GO:1902226 regulation of macrophage colony-stimulating factor signaling pathway(GO:1902226) regulation of response to macrophage colony-stimulating factor(GO:1903969) regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903972)
0.1 0.5 GO:0071484 cellular response to light intensity(GO:0071484) cellular response to high light intensity(GO:0071486) retinal rod cell apoptotic process(GO:0097473)
0.1 0.4 GO:0017183 peptidyl-diphthamide metabolic process(GO:0017182) peptidyl-diphthamide biosynthetic process from peptidyl-histidine(GO:0017183)
0.1 0.3 GO:0001920 negative regulation of receptor recycling(GO:0001920)
0.0 3.5 GO:0035690 cellular response to drug(GO:0035690)
0.0 0.1 GO:1900186 negative regulation of clathrin-mediated endocytosis(GO:1900186)
0.0 1.8 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.0 0.3 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.0 0.9 GO:0019884 antigen processing and presentation of exogenous antigen(GO:0019884)
0.0 0.1 GO:0071211 protein targeting to vacuole involved in autophagy(GO:0071211)
0.0 0.2 GO:1905171 protein localization to phagocytic vesicle(GO:1905161) regulation of protein localization to phagocytic vesicle(GO:1905169) positive regulation of protein localization to phagocytic vesicle(GO:1905171)
0.0 0.2 GO:2001183 negative regulation of interleukin-12 secretion(GO:2001183)
0.0 0.1 GO:0071288 cellular response to mercury ion(GO:0071288)
0.0 0.5 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.0 0.1 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.0 0.2 GO:1901409 positive regulation of phosphorylation of RNA polymerase II C-terminal domain(GO:1901409)
0.0 0.5 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.0 0.2 GO:0008063 Toll signaling pathway(GO:0008063)
0.0 0.3 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.1 GO:0018312 peptidyl-serine ADP-ribosylation(GO:0018312)
0.0 0.1 GO:0032329 serine transport(GO:0032329)
0.0 0.4 GO:0048671 negative regulation of collateral sprouting(GO:0048671)
0.0 0.5 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.2 GO:0046477 glycosylceramide catabolic process(GO:0046477)
0.0 0.3 GO:0035090 maintenance of apical/basal cell polarity(GO:0035090)
0.0 0.3 GO:0035428 hexose transmembrane transport(GO:0035428)
0.0 0.1 GO:0031441 negative regulation of mRNA 3'-end processing(GO:0031441)
0.0 0.1 GO:1904628 response to phorbol 13-acetate 12-myristate(GO:1904627) cellular response to phorbol 13-acetate 12-myristate(GO:1904628)
0.0 0.1 GO:0033085 negative regulation of T cell differentiation in thymus(GO:0033085) positive regulation of thymocyte apoptotic process(GO:0070245)
0.0 0.3 GO:0043011 myeloid dendritic cell differentiation(GO:0043011)
0.0 0.1 GO:0043652 engulfment of apoptotic cell(GO:0043652)
0.0 0.0 GO:1903251 multi-ciliated epithelial cell differentiation(GO:1903251)
0.0 0.2 GO:2001197 regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904259) positive regulation of basement membrane assembly involved in embryonic body morphogenesis(GO:1904261) basement membrane assembly involved in embryonic body morphogenesis(GO:2001197)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 4.1 GO:0042612 MHC class I protein complex(GO:0042612)
0.1 1.8 GO:0042555 MCM complex(GO:0042555)
0.1 0.6 GO:0008537 proteasome activator complex(GO:0008537)
0.1 0.3 GO:0097169 AIM2 inflammasome complex(GO:0097169)
0.1 0.3 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.0 0.8 GO:0035631 CD40 receptor complex(GO:0035631)
0.0 0.5 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.4 GO:0000015 phosphopyruvate hydratase complex(GO:0000015)
0.0 0.1 GO:0034272 phosphatidylinositol 3-kinase complex, class III, type I(GO:0034271) phosphatidylinositol 3-kinase complex, class III, type II(GO:0034272)
0.0 0.1 GO:0032127 dense core granule membrane(GO:0032127)
0.0 0.7 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.4 GO:0000506 glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex(GO:0000506)
0.0 0.6 GO:0042101 T cell receptor complex(GO:0042101)
0.0 0.7 GO:0080008 Cul4-RING E3 ubiquitin ligase complex(GO:0080008)
0.0 0.3 GO:0000137 Golgi cis cisterna(GO:0000137)
0.0 0.4 GO:0031616 spindle pole centrosome(GO:0031616)
0.0 0.1 GO:0016602 CCAAT-binding factor complex(GO:0016602)
0.0 0.1 GO:0045160 myosin I complex(GO:0045160)
0.0 0.1 GO:0005677 chromatin silencing complex(GO:0005677)
0.0 0.5 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.2 GO:0016589 NURF complex(GO:0016589)
0.0 0.1 GO:0005610 laminin-5 complex(GO:0005610)
0.0 0.5 GO:0001741 XY body(GO:0001741)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 4.1 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.3 1.0 GO:0036132 13-prostaglandin reductase activity(GO:0036132) 15-oxoprostaglandin 13-oxidase activity(GO:0047522)
0.1 1.5 GO:0061133 endopeptidase activator activity(GO:0061133)
0.1 0.6 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.1 0.3 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.1 0.5 GO:0032405 MutLalpha complex binding(GO:0032405)
0.1 0.5 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.1 0.2 GO:0052692 raffinose alpha-galactosidase activity(GO:0052692)
0.1 0.4 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.0 0.4 GO:1901612 cardiolipin binding(GO:1901612)
0.0 1.8 GO:0004003 ATP-dependent DNA helicase activity(GO:0004003)
0.0 0.3 GO:0001025 RNA polymerase III transcription factor binding(GO:0001025)
0.0 0.5 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.0 0.4 GO:0017176 phosphatidylinositol N-acetylglucosaminyltransferase activity(GO:0017176)
0.0 0.4 GO:0004634 phosphopyruvate hydratase activity(GO:0004634)
0.0 0.5 GO:0005528 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.8 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.3 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.1 GO:0004307 ethanolaminephosphotransferase activity(GO:0004307)
0.0 0.1 GO:0005223 intracellular cGMP activated cation channel activity(GO:0005223)
0.0 0.2 GO:0031996 thioesterase binding(GO:0031996)
0.0 0.4 GO:0008569 ATP-dependent microtubule motor activity, minus-end-directed(GO:0008569)
0.0 0.4 GO:0008143 poly(A) binding(GO:0008143)
0.0 0.1 GO:0004673 protein histidine kinase activity(GO:0004673)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 2.3 PID ATR PATHWAY ATR signaling pathway
0.0 1.3 ST GAQ PATHWAY G alpha q Pathway
0.0 0.3 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 0.7 PID TRAIL PATHWAY TRAIL signaling pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.8 REACTOME UNWINDING OF DNA Genes involved in Unwinding of DNA
0.1 0.8 REACTOME NFKB IS ACTIVATED AND SIGNALS SURVIVAL Genes involved in NF-kB is activated and signals survival
0.1 0.8 REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10 Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.1 0.5 REACTOME REGULATION OF THE FANCONI ANEMIA PATHWAY Genes involved in Regulation of the Fanconi anemia pathway
0.0 0.5 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.3 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 0.9 REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1 Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.0 0.2 REACTOME TRAF3 DEPENDENT IRF ACTIVATION PATHWAY Genes involved in TRAF3-dependent IRF activation pathway
0.0 0.2 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.0 0.2 REACTOME AUTODEGRADATION OF CDH1 BY CDH1 APC C Genes involved in Autodegradation of Cdh1 by Cdh1:APC/C
0.0 0.4 REACTOME KINESINS Genes involved in Kinesins
0.0 0.4 REACTOME SYNTHESIS OF GLYCOSYLPHOSPHATIDYLINOSITOL GPI Genes involved in Synthesis of glycosylphosphatidylinositol (GPI)