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avrg: GFI1 WT vs 36n/n vs KD

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Results for Homez

Z-value: 2.50

Motif logo

Transcription factors associated with Homez

Gene Symbol Gene ID Gene Info
ENSMUSG00000057156.11 homeodomain leucine zipper-encoding gene

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Homezmm39_v1_chr14_-_55108384_551084180.951.3e-02Click!

Activity profile of Homez motif

Sorted Z-values of Homez motif

Promoter Log-likelihood Transcript Gene Gene Info
chr2_-_151586063 1.77 ENSMUST00000109869.2
proteasome (prosome, macropain) inhibitor subunit 1
chr4_-_117035922 1.56 ENSMUST00000153953.2
ENSMUST00000106436.8
kinesin family member 2C
chr8_-_34578880 1.32 ENSMUST00000080152.5
predicted pseudogene 10131
chr15_-_38518406 1.21 ENSMUST00000151319.8
antizyme inhibitor 1
chr4_+_102617332 1.20 ENSMUST00000066824.14
SH3-domain GRB2-like (endophilin) interacting protein 1
chr19_-_6885657 1.14 ENSMUST00000149261.8
peroxiredoxin 5
chr11_-_40586029 1.08 ENSMUST00000101347.10
methionine adenosyltransferase II, beta
chr7_+_140462343 1.08 ENSMUST00000163610.9
ENSMUST00000164681.8
proteasome (prosome, macropain) 26S subunit, non-ATPase, 13
chr16_+_49620883 1.03 ENSMUST00000229640.2
CD47 antigen (Rh-related antigen, integrin-associated signal transducer)
chr17_+_37581103 1.01 ENSMUST00000038580.7
histocompatibility 2, M region locus 3
chr2_-_86180622 0.99 ENSMUST00000099894.5
ENSMUST00000213564.3
olfactory receptor 1055
chr1_-_118239146 0.96 ENSMUST00000027623.9
translin
chr18_-_42395207 0.96 ENSMUST00000097590.5
leucyl-tRNA synthetase
chr7_-_47139334 0.93 ENSMUST00000119798.3
MAS-related GPR, member A2B
chr7_+_140461860 0.93 ENSMUST00000026560.14
proteasome (prosome, macropain) 26S subunit, non-ATPase, 13
chr3_-_130503041 0.92 ENSMUST00000043937.9
oligosaccharyltransferase complex subunit (non-catalytic)
chr10_-_112764879 0.90 ENSMUST00000099276.4
ataxin 7-like 3B
chr4_-_116851550 0.89 ENSMUST00000130273.8
uroporphyrinogen decarboxylase
chr5_-_45607485 0.86 ENSMUST00000154962.8
ENSMUST00000118097.8
ENSMUST00000198258.5
quinoid dihydropteridine reductase
chr8_-_4829519 0.85 ENSMUST00000022945.9
Shc SH2-domain binding protein 1
chr2_+_71219561 0.82 ENSMUST00000028408.3
histone aminotransferase 1
chr8_-_108151661 0.82 ENSMUST00000003946.9
NIN1/RPN12 binding protein 1 homolog
chr3_-_100069680 0.82 ENSMUST00000052120.14
WD repeat domain 3
chr14_-_118370144 0.81 ENSMUST00000022727.10
ENSMUST00000228543.2
TDP-glucose 4,6-dehydratase
chr10_-_115198093 0.79 ENSMUST00000219890.2
ENSMUST00000218731.2
ENSMUST00000217887.2
ENSMUST00000092170.7
transmembrane protein 19
chr14_+_20344765 0.78 ENSMUST00000223663.2
ENSMUST00000022343.6
ENSMUST00000224066.2
ENSMUST00000223941.2
ENSMUST00000224311.2
nudix (nucleoside diphosphate linked moiety X)-type motif 13
chr3_-_50398027 0.78 ENSMUST00000029297.6
ENSMUST00000194462.6
solute carrier family 7 (cationic amino acid transporter, y+ system), member 11
chr1_-_162376053 0.78 ENSMUST00000028017.16
EEF1A lysine and N-terminal methyltransferase
chr11_-_48762170 0.77 ENSMUST00000049519.4
ENSMUST00000097271.4
immunity-related GTPase family M member 1
chr2_-_126342551 0.76 ENSMUST00000129187.2
ATPase, class I, type 8B, member 4
chr12_-_103392039 0.74 ENSMUST00000110001.4
ENSMUST00000223233.2
ENSMUST00000044923.15
ENSMUST00000221211.2
DEAD box helicase 24
chr2_-_23939401 0.71 ENSMUST00000051416.12
histamine N-methyltransferase
chr18_+_84106188 0.70 ENSMUST00000060223.4
zinc binding alcohol dehydrogenase, domain containing 2
chr12_-_40298072 0.69 ENSMUST00000169926.8
interferon-related developmental regulator 1
chrX_-_135644424 0.68 ENSMUST00000166478.8
ENSMUST00000113097.8
mortality factor 4 like 2
chr5_+_21990251 0.67 ENSMUST00000239497.2
ENSMUST00000030769.7
proteasome (prosome, macropain) 26S subunit, ATPase 2
chrM_+_7758 0.66 ENSMUST00000082407.1
mitochondrially encoded ATP synthase 8
chr9_-_39405284 0.66 ENSMUST00000077757.7
ENSMUST00000215065.3
ENSMUST00000216316.3
olfactory receptor 44
chrX_-_149879501 0.66 ENSMUST00000112683.9
ENSMUST00000026295.10
TSR2 20S rRNA accumulation
chr14_-_86986541 0.65 ENSMUST00000226254.2
diaphanous related formin 3
chr1_-_52271455 0.65 ENSMUST00000114512.8
glutaminase
chrY_-_1286623 0.64 ENSMUST00000091190.12
DEAD box helicase 3, Y-linked
chr18_-_64649497 0.64 ENSMUST00000237351.2
ENSMUST00000236186.2
ENSMUST00000235325.2
asparaginyl-tRNA synthetase
chr17_+_33212143 0.64 ENSMUST00000087666.11
ENSMUST00000157017.2
zinc finger protein 952
chr17_+_34423054 0.63 ENSMUST00000138491.2
transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
chr6_+_137731526 0.63 ENSMUST00000203216.3
ENSMUST00000087675.9
ENSMUST00000203693.3
deoxyribose-phosphate aldolase (putative)
chr2_-_69542805 0.63 ENSMUST00000102706.4
ENSMUST00000073152.13
FAST kinase domains 1
chr7_+_27869115 0.62 ENSMUST00000042405.8
fibrillarin
chr5_-_45607554 0.61 ENSMUST00000015950.12
quinoid dihydropteridine reductase
chr3_-_106057077 0.61 ENSMUST00000149836.2
chitinase-like 3
chr17_+_33212097 0.60 ENSMUST00000141815.3
zinc finger protein 952
chr11_+_109540201 0.60 ENSMUST00000106677.8
protein kinase, cAMP dependent regulatory, type I, alpha
chr1_-_34882131 0.60 ENSMUST00000167518.8
ENSMUST00000047534.12
family with sequence similarity 168, member B
chr4_-_116851571 0.60 ENSMUST00000030446.15
uroporphyrinogen decarboxylase
chr12_-_101943134 0.59 ENSMUST00000221227.2
NADH:ubiquinone oxidoreductase subunit B1
chr16_+_95946591 0.58 ENSMUST00000023913.11
ENSMUST00000232832.2
ENSMUST00000233566.2
ENSMUST00000233273.2
guided entry of tail-anchored proteins factor 1
chr10_+_19497740 0.58 ENSMUST00000036564.8
interleukin 22 receptor, alpha 2
chr15_+_79543397 0.58 ENSMUST00000023064.9
chibby family member 1, beta catenin antagonist
chr15_+_100251030 0.58 ENSMUST00000075675.7
ENSMUST00000088142.6
ENSMUST00000176287.2
methyltransferase hypoxia inducible domain containing 1
methyltransferase like 7A2
chr7_-_47101887 0.57 ENSMUST00000159004.2
MAS-related GPR, member A2A
chr10_-_17898838 0.57 ENSMUST00000220433.2
ABRA C-terminal like
chr15_+_102204691 0.57 ENSMUST00000064924.6
ENSMUST00000230212.2
ENSMUST00000229050.2
ENSMUST00000231104.2
extra spindle pole bodies 1, separase
chr4_-_123033721 0.56 ENSMUST00000030404.5
peptidylprolyl isomerase E (cyclophilin E)
chr13_-_19579898 0.55 ENSMUST00000197565.3
ENSMUST00000221380.2
ENSMUST00000200323.3
ENSMUST00000199924.2
ENSMUST00000222869.2
STARD3 N-terminal like
chr10_-_115197775 0.54 ENSMUST00000217848.2
transmembrane protein 19
chr7_-_140462221 0.53 ENSMUST00000026559.14
sirtuin 3
chr11_-_113540867 0.53 ENSMUST00000136392.8
ENSMUST00000125890.8
ENSMUST00000146031.8
solute carrier family 39 (metal ion transporter), member 11
chr10_+_61516078 0.53 ENSMUST00000220372.2
ENSMUST00000020285.10
ENSMUST00000219506.2
ENSMUST00000218474.2
secretion associated Ras related GTPase 1A
chr3_+_51323383 0.53 ENSMUST00000029303.13
N(alpha)-acetyltransferase 15, NatA auxiliary subunit
chr7_-_30364394 0.53 ENSMUST00000019697.9
HAUS augmin-like complex, subunit 5
chr13_+_67052978 0.53 ENSMUST00000168767.9
predicted gene 10767
chr6_-_69282389 0.52 ENSMUST00000103350.3
immunoglobulin kappa variable 4-68
chr8_-_117648104 0.52 ENSMUST00000128304.2
COX assembly mitochondrial protein 2
chr7_+_28416270 0.51 ENSMUST00000108279.9
F-box protein 17
chr1_+_132405099 0.51 ENSMUST00000190825.7
ENSMUST00000190997.7
ENSMUST00000187505.7
ENSMUST00000027700.15
ENSMUST00000188575.7
retinoblastoma binding protein 5, histone lysine methyltransferase complex subunit
chr6_+_58617521 0.51 ENSMUST00000145161.8
ENSMUST00000203146.3
ENSMUST00000114294.8
ENSMUST00000204948.2
ATP binding cassette subfamily G member 2 (Junior blood group)
chr5_+_140404997 0.51 ENSMUST00000100507.8
eukaryotic translation initiation factor 3, subunit B
chr10_-_81200680 0.51 ENSMUST00000131736.8
RIKEN cDNA 4930404N11 gene
chr2_+_118865262 0.50 ENSMUST00000028796.2
RNA pseudouridylate synthase domain containing 2
chr11_-_96807233 0.50 ENSMUST00000130774.2
CDK5 regulatory subunit associated protein 3
chr17_-_81372483 0.50 ENSMUST00000025093.6
THUMP domain containing 2
chr15_+_100052260 0.50 ENSMUST00000023768.14
disco interacting protein 2 homolog B
chr8_+_70625032 0.50 ENSMUST00000002413.15
ENSMUST00000182980.8
ENSMUST00000182365.8
transmembrane protein 161A
chr1_+_171041539 0.49 ENSMUST00000005820.11
ENSMUST00000075469.12
ENSMUST00000155126.8
nuclear receptor subfamily 1, group I, member 3
chr9_+_74959259 0.49 ENSMUST00000170310.2
ENSMUST00000166549.2
cAMP-regulated phosphoprotein 19
chr11_-_51541610 0.49 ENSMUST00000142721.2
ENSMUST00000156835.8
ENSMUST00000001080.16
NEDD4 binding protein 3
chr9_-_111086528 0.49 ENSMUST00000199404.2
mutL homolog 1
chr6_+_134617903 0.49 ENSMUST00000062755.10
BLOC-1 related complex subunit 5
chr7_-_140461769 0.49 ENSMUST00000106048.10
ENSMUST00000147331.9
ENSMUST00000137710.2
sirtuin 3
chr12_-_99849660 0.48 ENSMUST00000221929.2
ENSMUST00000046485.5
EF-hand calcium binding domain 11
chr8_-_111754379 0.48 ENSMUST00000040241.15
DEAD box helicase 19b
chr8_-_117648147 0.47 ENSMUST00000078589.7
ENSMUST00000148235.8
COX assembly mitochondrial protein 2
chr8_-_73059104 0.47 ENSMUST00000075602.8
predicted pseudogene 10282
chr17_+_24645615 0.47 ENSMUST00000234304.2
ENSMUST00000024946.7
ENSMUST00000234150.2
enoyl-Coenzyme A delta isomerase 1
chr2_-_93292257 0.46 ENSMUST00000150508.8
CD82 antigen
chr9_-_36637923 0.46 ENSMUST00000034625.12
checkpoint kinase 1
chr7_+_27869192 0.46 ENSMUST00000208967.2
fibrillarin
chr9_+_89081407 0.46 ENSMUST00000138109.2
predicted gene 29094
chr4_-_46389391 0.45 ENSMUST00000086563.11
ENSMUST00000030015.6
tRNA methyltransferase O
chr7_+_119701570 0.45 ENSMUST00000033210.13
transmembrane protein 159
chr1_-_163822336 0.45 ENSMUST00000097493.10
ENSMUST00000045876.8
cDNA sequence BC055324
chr6_-_69415741 0.45 ENSMUST00000103354.3
immunoglobulin kappa variable 4-59
chr5_+_52940391 0.45 ENSMUST00000031077.13
ENSMUST00000113904.9
ENSMUST00000199840.2
zinc finger, CCHC domain containing 4
chr12_+_17398421 0.44 ENSMUST00000046011.12
nucleolar protein 10
chr17_-_30790804 0.44 ENSMUST00000236799.2
ENSMUST00000237048.2
BTB (POZ) domain containing 9
chr2_-_93292708 0.44 ENSMUST00000123565.8
CD82 antigen
chr9_-_21223551 0.44 ENSMUST00000003397.9
ENSMUST00000213250.2
adaptor protein complex AP-1, mu 2 subunit
chr15_+_9071761 0.43 ENSMUST00000189437.8
ENSMUST00000190874.8
NAD kinase 2, mitochondrial
chr8_+_117648474 0.43 ENSMUST00000034205.5
ENSMUST00000212775.2
centromere protein N
chr5_+_115061293 0.43 ENSMUST00000031540.11
ENSMUST00000112143.4
2'-5' oligoadenylate synthetase-like 1
chr17_+_21876498 0.43 ENSMUST00000039726.8
zinc finger protein 983
chr11_+_88095222 0.43 ENSMUST00000118784.8
ENSMUST00000139170.8
ENSMUST00000107915.10
ENSMUST00000144070.3
mitochondrial ribosomal protein S23
chr16_-_91728162 0.42 ENSMUST00000139277.8
ENSMUST00000154661.8
ATP synthase, H+ transporting, mitochondrial F1 complex, O subunit
chr15_+_90108480 0.42 ENSMUST00000100309.3
ENSMUST00000231200.2
asparagine-linked glycosylation 10B (alpha-1,2-glucosyltransferase)
chr13_+_21363602 0.42 ENSMUST00000222544.2
tripartite motif-containing 27
chr18_-_64649620 0.41 ENSMUST00000025483.11
ENSMUST00000237400.2
asparaginyl-tRNA synthetase
chr18_+_50164043 0.41 ENSMUST00000145726.2
ENSMUST00000128377.2
tumor necrosis factor, alpha-induced protein 8
chr4_-_115911053 0.41 ENSMUST00000030475.3
NOL1/NOP2/Sun domain family, member 4
chr10_+_42554888 0.41 ENSMUST00000040718.6
osteopetrosis associated transmembrane protein 1
chr11_+_103007054 0.41 ENSMUST00000053063.7
hexamethylene bis-acetamide inducible 1
chr11_+_116744578 0.41 ENSMUST00000021173.14
major facilitator superfamily domain containing 11
chr13_-_8921732 0.40 ENSMUST00000054251.13
ENSMUST00000176813.8
ENSMUST00000175958.2
WD repeat domain 37
chr14_-_47514248 0.40 ENSMUST00000187531.8
ENSMUST00000111790.2
WD repeat and HMG-box DNA binding protein 1
chr16_-_20121108 0.40 ENSMUST00000048642.15
ENSMUST00000232036.2
presenilin associated, rhomboid-like
chr3_+_36120195 0.40 ENSMUST00000196648.2
acyl-Coenzyme A dehydrogenase family, member 9
chr2_-_103591271 0.40 ENSMUST00000140895.2
N-acetyltransferase 10
chr13_-_53531391 0.39 ENSMUST00000021920.8
serine palmitoyltransferase, long chain base subunit 1
chr2_+_30171055 0.39 ENSMUST00000143119.3
predicted gene, 28038
chr2_+_61542038 0.39 ENSMUST00000028278.14
proteasome (prosome, macropain) 26S subunit, non-ATPase, 14
chr1_+_59724108 0.39 ENSMUST00000027174.10
ENSMUST00000190231.7
ENSMUST00000191142.7
ENSMUST00000185772.7
NOP58 ribonucleoprotein
chr15_+_31602252 0.39 ENSMUST00000042702.7
ENSMUST00000161061.3
ATP synthase C subunit lysine N-methyltransferase
chr13_-_19579961 0.39 ENSMUST00000039694.13
STARD3 N-terminal like
chr1_-_80255156 0.38 ENSMUST00000168372.2
cullin 3
chr10_+_129219952 0.38 ENSMUST00000214064.2
olfactory receptor 784
chr8_-_108315024 0.38 ENSMUST00000044106.6
proteasome (prosome, macropain) 26S subunit, non-ATPase, 7
chr1_+_163822438 0.38 ENSMUST00000045694.14
ENSMUST00000111490.2
methyltransferase like 18
chr17_+_15277013 0.37 ENSMUST00000228803.2
ER membrane associated RNA degradation
chr13_-_45155298 0.37 ENSMUST00000220555.2
dystrobrevin binding protein 1
chr11_+_120489358 0.37 ENSMUST00000093140.5
anaphase promoting complex subunit 11
chr19_-_46958001 0.36 ENSMUST00000235234.2
5'-nucleotidase, cytosolic II
chr6_-_39396691 0.36 ENSMUST00000146785.8
ENSMUST00000114823.8
makorin, ring finger protein, 1
chr15_+_9071331 0.36 ENSMUST00000190591.10
NAD kinase 2, mitochondrial
chr11_+_23616007 0.36 ENSMUST00000058163.11
pseudouridylate synthase 10
chr5_-_5564730 0.36 ENSMUST00000115445.8
ENSMUST00000179804.8
ENSMUST00000125110.2
ENSMUST00000115446.8
claudin 12
chr7_-_45116316 0.36 ENSMUST00000033093.10
BCL2-associated X protein
chr5_+_45650821 0.35 ENSMUST00000198534.2
leucine aminopeptidase 3
chr11_+_88095206 0.35 ENSMUST00000024486.14
mitochondrial ribosomal protein S23
chr2_-_152185901 0.35 ENSMUST00000040312.7
tribbles pseudokinase 3
chr14_-_104760051 0.35 ENSMUST00000022716.4
ENSMUST00000228448.2
ENSMUST00000227640.2
ORC ubiquitin ligase 1
chr19_-_4240984 0.35 ENSMUST00000045864.4
TBC1 domain family, member 10c
chr13_-_92620507 0.34 ENSMUST00000040106.9
family with sequence similarity 151, member B
chr6_-_125208738 0.34 ENSMUST00000043422.8
TAP binding protein-like
chrM_+_7779 0.34 ENSMUST00000082408.1
mitochondrially encoded ATP synthase 6
chr5_-_110256019 0.34 ENSMUST00000077220.14
GTP binding protein 6 (putative)
chr6_+_71350411 0.33 ENSMUST00000066747.14
CD8 antigen, alpha chain
chr3_+_36120128 0.33 ENSMUST00000011492.15
acyl-Coenzyme A dehydrogenase family, member 9
chr14_-_27230402 0.33 ENSMUST00000050480.8
ENSMUST00000223689.2
coiled-coil domain containing 66
chr11_-_62172164 0.33 ENSMUST00000072916.5
zinc finger SWIM-type containing 7
chr7_+_51537645 0.32 ENSMUST00000208711.2
growth arrest specific 2
chr5_+_100666278 0.31 ENSMUST00000151414.8
COP9 signalosome subunit 4
chr18_-_42395131 0.31 ENSMUST00000236102.2
leucyl-tRNA synthetase
chr9_+_55057334 0.31 ENSMUST00000122441.2
ubiquitin-conjugating enzyme E2Q family member 2
chr2_-_103591522 0.30 ENSMUST00000028608.13
N-acetyltransferase 10
chr3_-_107839133 0.30 ENSMUST00000004137.11
glutathione S-transferase, mu 7
chr2_-_174305856 0.30 ENSMUST00000016396.8
ATP synthase, H+ transporting, mitochondrial F1 complex, epsilon subunit
chr3_-_148696155 0.30 ENSMUST00000196526.5
ENSMUST00000200543.5
ENSMUST00000200154.5
adhesion G protein-coupled receptor L2
chr1_-_180971763 0.29 ENSMUST00000027797.9
nuclear VCP-like
chr5_-_21990170 0.29 ENSMUST00000115193.8
ENSMUST00000115192.2
ENSMUST00000115195.8
ENSMUST00000030771.12
DnaJ heat shock protein family (Hsp40) member C2
chr4_-_126954878 0.29 ENSMUST00000136186.2
ENSMUST00000106099.8
ENSMUST00000106102.9
zinc finger, MYM domain containing 1
chr5_-_149559636 0.29 ENSMUST00000201452.4
heat shock 105kDa/110kDa protein 1
chr2_-_86109346 0.29 ENSMUST00000217294.2
ENSMUST00000217245.2
ENSMUST00000216432.2
olfactory receptor 1051
chr2_-_30249202 0.29 ENSMUST00000100215.11
ENSMUST00000113620.10
ENSMUST00000163668.3
ENSMUST00000028214.15
ENSMUST00000113621.10
SH3-domain GRB2-like endophilin B2
chr5_-_149559667 0.29 ENSMUST00000074846.14
heat shock 105kDa/110kDa protein 1
chr3_+_90128086 0.29 ENSMUST00000065418.7
RAB13, member RAS oncogene family
chr15_-_36792649 0.29 ENSMUST00000126184.2
tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta polypeptide
chr9_+_19533374 0.29 ENSMUST00000213725.2
ENSMUST00000208694.2
zinc finger protein 317
chr1_+_33758937 0.28 ENSMUST00000088287.10
RAB23, member RAS oncogene family
chr6_+_71350519 0.28 ENSMUST00000172321.3
CD8 antigen, alpha chain
chr2_+_85809620 0.27 ENSMUST00000056849.3
olfactory receptor 1030
chr12_+_65122355 0.27 ENSMUST00000058889.5
Fanconi anemia, complementation group M
chr11_+_101518768 0.27 ENSMUST00000010506.10
RAD52 motif 1
chr18_-_70663382 0.27 ENSMUST00000043286.15
polymerase (DNA directed), iota
chrX_+_105059305 0.27 ENSMUST00000033582.5
cytochrome c oxidase subunit 7B
chr7_-_37927399 0.27 ENSMUST00000098513.6
pleckstrin homology domain containing, family F (with FYVE domain) member 1
chr7_-_100164007 0.26 ENSMUST00000207405.2
DnaJ heat shock protein family (Hsp40) member B13
chr2_-_93292734 0.26 ENSMUST00000099696.8
CD82 antigen
chr5_-_149559792 0.25 ENSMUST00000202361.4
ENSMUST00000202089.4
ENSMUST00000200825.2
ENSMUST00000201559.4
heat shock 105kDa/110kDa protein 1
chr1_+_4928260 0.25 ENSMUST00000165720.3
transcription elongation factor A (SII) 1
chr5_-_8472582 0.24 ENSMUST00000168500.8
ENSMUST00000002368.16
DBF4 zinc finger
chr6_-_54949587 0.24 ENSMUST00000060655.15
nucleotide-binding oligomerization domain containing 1
chr1_+_121358778 0.24 ENSMUST00000036025.16
ENSMUST00000112621.2
coiled-coil domain containing 93
chr13_-_117161921 0.24 ENSMUST00000223949.2
poly (ADP-ribose) polymerase family, member 8
chr18_-_24663260 0.24 ENSMUST00000046206.5
regulation of nuclear pre-mRNA domain containing 1A
chr1_+_78635542 0.24 ENSMUST00000035779.15
acyl-CoA synthetase long-chain family member 3
chr2_-_180928867 0.23 ENSMUST00000130475.8
glucocorticoid modulatory element binding protein 2
chr8_-_70959360 0.23 ENSMUST00000136913.2
ENSMUST00000075175.12
required for excision 1-B domain containing
chr7_-_46558754 0.23 ENSMUST00000209538.2
tumor susceptibility gene 101
chrX_+_36059274 0.23 ENSMUST00000016463.4
solute carrier family 25 (mitochondrial carrier, adenine nucleotide translocator), member 5
chr13_-_25204272 0.23 ENSMUST00000021772.4
MRS2 magnesium transporter
chr12_-_79030250 0.23 ENSMUST00000070174.14
transmembrane protein 229B

Network of associatons between targets according to the STRING database.

First level regulatory network of Homez

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.6 GO:0002477 antigen processing and presentation of endogenous peptide antigen via MHC class Ib(GO:0002476) antigen processing and presentation of exogenous peptide antigen via MHC class Ib(GO:0002477) antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent(GO:0002481)
0.4 1.3 GO:0006429 leucyl-tRNA aminoacylation(GO:0006429)
0.3 1.2 GO:1902269 positive regulation of polyamine transmembrane transport(GO:1902269)
0.3 1.5 GO:0046502 uroporphyrinogen III metabolic process(GO:0046502)
0.3 1.1 GO:0060785 regulation of apoptosis involved in tissue homeostasis(GO:0060785)
0.3 1.1 GO:0018364 peptidyl-glutamine methylation(GO:0018364)
0.3 1.6 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951)
0.2 1.0 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.2 1.1 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.2 0.7 GO:0002101 tRNA wobble cytosine modification(GO:0002101)
0.2 0.5 GO:0019389 glucuronoside metabolic process(GO:0019389)
0.2 0.5 GO:0010767 regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage(GO:0010767)
0.1 1.5 GO:0006729 tetrahydrobiopterin biosynthetic process(GO:0006729)
0.1 0.6 GO:0061646 positive regulation of glutamate neurotransmitter secretion in response to membrane depolarization(GO:0061646)
0.1 0.7 GO:0001692 histamine metabolic process(GO:0001692)
0.1 0.4 GO:0006667 sphinganine metabolic process(GO:0006667)
0.1 0.6 GO:0046121 deoxyribonucleoside catabolic process(GO:0046121)
0.1 2.0 GO:0043248 proteasome assembly(GO:0043248)
0.1 0.5 GO:0051311 meiotic metaphase I plate congression(GO:0043060) meiotic metaphase plate congression(GO:0051311)
0.1 0.4 GO:1990117 release of matrix enzymes from mitochondria(GO:0032976) B cell receptor apoptotic signaling pathway(GO:1990117)
0.1 0.3 GO:0002589 regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590)
0.1 0.8 GO:0060332 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.1 0.3 GO:0060060 post-embryonic retina morphogenesis in camera-type eye(GO:0060060)
0.1 0.7 GO:0006543 glutamine catabolic process(GO:0006543)
0.1 1.0 GO:0006741 NADP biosynthetic process(GO:0006741)
0.1 1.0 GO:1903753 negative regulation of p38MAPK cascade(GO:1903753)
0.1 1.2 GO:0034983 peptidyl-lysine deacetylation(GO:0034983)
0.1 1.0 GO:0008228 opsonization(GO:0008228)
0.1 0.5 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089)
0.1 0.4 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
0.1 0.4 GO:0070829 heterochromatin maintenance(GO:0070829)
0.1 0.9 GO:1902101 positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.1 0.6 GO:0071569 protein ufmylation(GO:0071569)
0.1 0.4 GO:0048254 snoRNA localization(GO:0048254)
0.1 1.2 GO:2000507 positive regulation of energy homeostasis(GO:2000507)
0.1 0.8 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.1 0.5 GO:0075525 viral translational termination-reinitiation(GO:0075525)
0.1 0.8 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.1 0.4 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.1 0.6 GO:0045065 cytotoxic T cell differentiation(GO:0045065)
0.1 0.6 GO:0006030 chitin metabolic process(GO:0006030) chitin catabolic process(GO:0006032)
0.1 0.3 GO:1904158 axonemal central apparatus assembly(GO:1904158)
0.1 0.2 GO:0006407 cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000448) rRNA export from nucleus(GO:0006407)
0.1 0.4 GO:0042256 mature ribosome assembly(GO:0042256)
0.1 0.5 GO:0017196 N-terminal peptidyl-methionine acetylation(GO:0017196)
0.1 0.2 GO:2000397 regulation of ubiquitin-dependent endocytosis(GO:2000395) positive regulation of ubiquitin-dependent endocytosis(GO:2000397)
0.1 0.6 GO:0002468 dendritic cell antigen processing and presentation(GO:0002468)
0.1 0.2 GO:0060217 hemangioblast cell differentiation(GO:0060217)
0.1 0.3 GO:0051410 detoxification of nitrogen compound(GO:0051410) cellular detoxification of nitrogen compound(GO:0070458)
0.1 0.5 GO:0031118 rRNA pseudouridine synthesis(GO:0031118)
0.0 0.3 GO:0090168 Golgi reassembly(GO:0090168)
0.0 1.3 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.8 GO:0000469 cleavage involved in rRNA processing(GO:0000469)
0.0 0.2 GO:1903378 positive regulation of oxidative stress-induced neuron intrinsic apoptotic signaling pathway(GO:1903378)
0.0 0.6 GO:0046007 negative regulation of activated T cell proliferation(GO:0046007)
0.0 0.4 GO:0031119 tRNA pseudouridine synthesis(GO:0031119)
0.0 0.2 GO:0070178 D-serine metabolic process(GO:0070178)
0.0 0.1 GO:0000350 generation of catalytic spliceosome for second transesterification step(GO:0000350) mRNA 3'-splice site recognition(GO:0000389)
0.0 0.3 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
0.0 0.1 GO:0038108 negative regulation of appetite by leptin-mediated signaling pathway(GO:0038108)
0.0 0.1 GO:0042998 positive regulation of Golgi to plasma membrane protein transport(GO:0042998) positive regulation of establishment of protein localization to plasma membrane(GO:0090004) regulation of phosphatidylcholine biosynthetic process(GO:2001245)
0.0 0.1 GO:0044837 assembly of actomyosin apparatus involved in cytokinesis(GO:0000912) actomyosin contractile ring assembly(GO:0000915) actomyosin contractile ring organization(GO:0044837)
0.0 1.9 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 1.6 GO:0030490 maturation of SSU-rRNA(GO:0030490)
0.0 0.8 GO:0051307 meiotic chromosome separation(GO:0051307)
0.0 0.9 GO:0043968 histone H2A acetylation(GO:0043968)
0.0 0.3 GO:0097368 establishment of Sertoli cell barrier(GO:0097368)
0.0 0.7 GO:0048671 negative regulation of collateral sprouting(GO:0048671)
0.0 0.2 GO:1900264 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.0 0.4 GO:0060586 multicellular organismal iron ion homeostasis(GO:0060586)
0.0 0.3 GO:0002098 tRNA wobble uridine modification(GO:0002098)
0.0 0.2 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.0 0.3 GO:0071494 cellular response to UV-C(GO:0071494)
0.0 0.4 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.0 0.2 GO:1901029 negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway(GO:1901029)
0.0 0.5 GO:0000338 protein deneddylation(GO:0000338)
0.0 0.1 GO:0038091 VEGF-activated platelet-derived growth factor receptor signaling pathway(GO:0038086) positive regulation of cell proliferation by VEGF-activated platelet derived growth factor receptor signaling pathway(GO:0038091)
0.0 0.2 GO:0070940 dephosphorylation of RNA polymerase II C-terminal domain(GO:0070940)
0.0 0.1 GO:0046136 positive regulation of vitamin metabolic process(GO:0046136) positive regulation of vitamin D biosynthetic process(GO:0060557) positive regulation of calcidiol 1-monooxygenase activity(GO:0060559)
0.0 0.1 GO:0010968 regulation of microtubule nucleation(GO:0010968)
0.0 0.4 GO:0045717 negative regulation of fatty acid biosynthetic process(GO:0045717)
0.0 0.1 GO:0090116 C-5 methylation of cytosine(GO:0090116) positive regulation of methylation-dependent chromatin silencing(GO:0090309)
0.0 0.4 GO:0045899 positive regulation of RNA polymerase II transcriptional preinitiation complex assembly(GO:0045899)
0.0 0.2 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.0 0.4 GO:0046085 adenosine metabolic process(GO:0046085)
0.0 0.1 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.2 GO:0035726 common myeloid progenitor cell proliferation(GO:0035726)
0.0 0.4 GO:0030488 tRNA methylation(GO:0030488)
0.0 0.0 GO:1904736 negative regulation of electron carrier activity(GO:1904733) regulation of fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:1904735) negative regulation of fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:1904736)
0.0 0.2 GO:0046477 glycoside catabolic process(GO:0016139) glycosylceramide catabolic process(GO:0046477)
0.0 0.2 GO:0034244 negative regulation of transcription elongation from RNA polymerase II promoter(GO:0034244)
0.0 0.7 GO:0032981 NADH dehydrogenase complex assembly(GO:0010257) mitochondrial respiratory chain complex I assembly(GO:0032981) mitochondrial respiratory chain complex I biogenesis(GO:0097031)
0.0 0.2 GO:0035879 lactate transport(GO:0015727) lactate transmembrane transport(GO:0035873) plasma membrane lactate transport(GO:0035879)
0.0 0.5 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 0.5 GO:0045722 positive regulation of gluconeogenesis(GO:0045722)
0.0 0.5 GO:1902230 negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage(GO:1902230)
0.0 0.7 GO:0045070 positive regulation of viral genome replication(GO:0045070)
0.0 0.4 GO:0090201 negative regulation of release of cytochrome c from mitochondria(GO:0090201)
0.0 0.2 GO:0035970 peptidyl-threonine dephosphorylation(GO:0035970)
0.0 0.4 GO:0034508 centromere complex assembly(GO:0034508)
0.0 0.4 GO:1901798 positive regulation of signal transduction by p53 class mediator(GO:1901798)
0.0 0.0 GO:0072233 ascending thin limb development(GO:0072021) thick ascending limb development(GO:0072023) metanephric ascending thin limb development(GO:0072218) metanephric thick ascending limb development(GO:0072233)
0.0 0.7 GO:0045599 negative regulation of fat cell differentiation(GO:0045599)
0.0 0.1 GO:0090611 ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611)
0.0 0.2 GO:0015693 magnesium ion transport(GO:0015693)
0.0 0.3 GO:0097094 craniofacial suture morphogenesis(GO:0097094)
0.0 0.4 GO:0070536 protein K63-linked deubiquitination(GO:0070536)
0.0 0.1 GO:0046606 negative regulation of centrosome duplication(GO:0010826) negative regulation of centrosome cycle(GO:0046606)
0.0 0.2 GO:0032463 negative regulation of protein homooligomerization(GO:0032463)
0.0 0.6 GO:0006829 zinc II ion transport(GO:0006829)
0.0 0.1 GO:0006449 regulation of translational termination(GO:0006449)
0.0 0.2 GO:1901223 negative regulation of NIK/NF-kappaB signaling(GO:1901223)
0.0 0.2 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.0 0.1 GO:0045719 negative regulation of glycogen biosynthetic process(GO:0045719)
0.0 0.0 GO:0042128 nitrate assimilation(GO:0042128)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.2 2.4 GO:0008541 proteasome regulatory particle, lid subcomplex(GO:0008541)
0.2 1.5 GO:0031428 box C/D snoRNP complex(GO:0031428)
0.2 0.5 GO:0005712 chiasma(GO:0005712)
0.1 0.4 GO:0097144 BAX complex(GO:0097144)
0.1 0.8 GO:0034388 Pwp2p-containing subcomplex of 90S preribosome(GO:0034388)
0.1 1.4 GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.1 0.7 GO:0031595 nuclear proteasome complex(GO:0031595)
0.1 1.3 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.1 0.6 GO:0042825 TAP complex(GO:0042825)
0.1 0.4 GO:0035339 SPOTS complex(GO:0035339)
0.1 0.9 GO:0008250 oligosaccharyltransferase complex(GO:0008250)
0.1 1.0 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.1 0.3 GO:0071821 FANCM-MHF complex(GO:0071821)
0.1 1.2 GO:0030122 AP-2 adaptor complex(GO:0030122)
0.1 0.5 GO:0098574 cytoplasmic side of lysosomal membrane(GO:0098574)
0.1 0.5 GO:0070652 HAUS complex(GO:0070652)
0.1 0.4 GO:0044611 nuclear pore inner ring(GO:0044611)
0.1 0.2 GO:0033193 Lsd1/2 complex(GO:0033193)
0.0 0.8 GO:0044754 autolysosome(GO:0044754)
0.0 0.4 GO:0005827 polar microtubule(GO:0005827)
0.0 0.4 GO:0005838 proteasome regulatory particle(GO:0005838)
0.0 0.2 GO:0071817 MMXD complex(GO:0071817)
0.0 0.4 GO:0070545 PeBoW complex(GO:0070545)
0.0 0.9 GO:0044232 organelle membrane contact site(GO:0044232)
0.0 0.5 GO:0031415 NatA complex(GO:0031415)
0.0 0.9 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.6 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.5 GO:0044666 MLL3/4 complex(GO:0044666)
0.0 1.1 GO:0005782 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.2 GO:0005663 DNA replication factor C complex(GO:0005663)
0.0 1.0 GO:0042611 MHC protein complex(GO:0042611)
0.0 1.0 GO:0005697 telomerase holoenzyme complex(GO:0005697)
0.0 1.6 GO:0035371 microtubule plus-end(GO:0035371)
0.0 0.3 GO:0000275 mitochondrial proton-transporting ATP synthase complex, catalytic core F(1)(GO:0000275) proton-transporting ATP synthase complex, catalytic core F(1)(GO:0045261)
0.0 0.2 GO:0001652 granular component(GO:0001652)
0.0 0.9 GO:1902562 NuA4 histone acetyltransferase complex(GO:0035267) H4/H2A histone acetyltransferase complex(GO:0043189) H4 histone acetyltransferase complex(GO:1902562)
0.0 0.9 GO:0005763 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.2 GO:0070847 core mediator complex(GO:0070847)
0.0 0.2 GO:0071541 eukaryotic translation initiation factor 3 complex, eIF3m(GO:0071541)
0.0 1.7 GO:0000502 proteasome complex(GO:0000502)
0.0 0.2 GO:0000813 ESCRT I complex(GO:0000813)
0.0 0.2 GO:0034464 BBSome(GO:0034464)
0.0 0.4 GO:0030131 clathrin adaptor complex(GO:0030131)
0.0 0.5 GO:0005680 anaphase-promoting complex(GO:0005680)
0.0 0.2 GO:0032593 insulin-responsive compartment(GO:0032593)
0.0 0.3 GO:0045277 respiratory chain complex IV(GO:0045277)
0.0 0.2 GO:0031464 Cul4A-RING E3 ubiquitin ligase complex(GO:0031464)
0.0 0.2 GO:0005845 mRNA cap binding complex(GO:0005845) RNA cap binding complex(GO:0034518)
0.0 0.4 GO:0005669 transcription factor TFIID complex(GO:0005669)
0.0 0.4 GO:0030904 retromer complex(GO:0030904)
0.0 0.1 GO:0030123 AP-3 adaptor complex(GO:0030123)
0.0 0.1 GO:0071014 post-mRNA release spliceosomal complex(GO:0071014)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.5 GO:0004155 6,7-dihydropteridine reductase activity(GO:0004155)
0.4 1.3 GO:0004823 glutamine-tRNA ligase activity(GO:0004819) leucine-tRNA ligase activity(GO:0004823)
0.3 1.2 GO:0042978 ornithine decarboxylase activator activity(GO:0042978)
0.3 1.1 GO:0072541 peroxynitrite reductase activity(GO:0072541)
0.3 1.0 GO:0004816 asparagine-tRNA ligase activity(GO:0004816)
0.2 0.6 GO:0015433 peptide antigen-transporting ATPase activity(GO:0015433) tapasin binding(GO:0046980)
0.2 0.7 GO:0047522 13-prostaglandin reductase activity(GO:0036132) 15-oxoprostaglandin 13-oxidase activity(GO:0047522)
0.2 0.5 GO:0016426 tRNA (adenine) methyltransferase activity(GO:0016426)
0.1 0.4 GO:0009383 rRNA (cytosine-C5-)-methyltransferase activity(GO:0009383)
0.1 0.5 GO:0032137 guanine/thymine mispair binding(GO:0032137)
0.1 0.5 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.1 0.8 GO:0000099 sulfur amino acid transmembrane transporter activity(GO:0000099)
0.1 0.7 GO:0004359 glutaminase activity(GO:0004359)
0.1 1.1 GO:0001094 TFIID-class transcription factor binding(GO:0001094)
0.1 0.7 GO:0061629 RNA polymerase II sequence-specific DNA binding transcription factor binding(GO:0061629)
0.1 0.7 GO:0036402 proteasome-activating ATPase activity(GO:0036402)
0.1 0.4 GO:0031208 POZ domain binding(GO:0031208)
0.1 0.5 GO:0004563 beta-N-acetylhexosaminidase activity(GO:0004563)
0.1 0.5 GO:0004165 dodecenoyl-CoA delta-isomerase activity(GO:0004165)
0.1 1.0 GO:0070053 thrombospondin receptor activity(GO:0070053)
0.1 1.0 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.1 2.2 GO:0070628 proteasome binding(GO:0070628)
0.1 0.4 GO:0016454 serine C-palmitoyltransferase activity(GO:0004758) C-palmitoyltransferase activity(GO:0016454)
0.1 0.5 GO:0019784 NEDD8-specific protease activity(GO:0019784)
0.1 1.2 GO:0070403 NAD+ binding(GO:0070403)
0.1 0.2 GO:0047661 racemase and epimerase activity, acting on amino acids and derivatives(GO:0016855) racemase activity, acting on amino acids and derivatives(GO:0036361) amino-acid racemase activity(GO:0047661)
0.1 1.6 GO:0051010 microtubule plus-end binding(GO:0051010)
0.1 0.2 GO:0052692 raffinose alpha-galactosidase activity(GO:0052692)
0.1 0.3 GO:0061649 ubiquitinated histone binding(GO:0061649)
0.1 0.5 GO:0008559 xenobiotic-transporting ATPase activity(GO:0008559)
0.0 0.9 GO:0009982 pseudouridine synthase activity(GO:0009982)
0.0 0.2 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.0 0.1 GO:0031871 proteinase activated receptor binding(GO:0031871)
0.0 0.3 GO:0016300 tRNA (uracil) methyltransferase activity(GO:0016300)
0.0 1.5 GO:0008198 ferrous iron binding(GO:0008198)
0.0 0.6 GO:0008603 cAMP-dependent protein kinase regulator activity(GO:0008603)
0.0 0.1 GO:0005017 platelet-derived growth factor-activated receptor activity(GO:0005017)
0.0 0.7 GO:0046933 proton-transporting ATP synthase activity, rotational mechanism(GO:0046933)
0.0 0.5 GO:0004887 thyroid hormone receptor activity(GO:0004887)
0.0 0.4 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.4 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.0 0.4 GO:0097322 7SK snRNA binding(GO:0097322)
0.0 0.5 GO:0004596 peptide alpha-N-acetyltransferase activity(GO:0004596)
0.0 1.0 GO:0003951 NAD+ kinase activity(GO:0003951)
0.0 0.7 GO:0003995 acyl-CoA dehydrogenase activity(GO:0003995)
0.0 0.6 GO:0016832 aldehyde-lyase activity(GO:0016832)
0.0 0.6 GO:0097371 MDM2/MDM4 family protein binding(GO:0097371)
0.0 0.8 GO:0010485 H4 histone acetyltransferase activity(GO:0010485)
0.0 0.4 GO:0046527 glucosyltransferase activity(GO:0046527)
0.0 1.0 GO:0042605 peptide antigen binding(GO:0042605)
0.0 0.5 GO:0034450 ubiquitin-ubiquitin ligase activity(GO:0034450)
0.0 0.1 GO:0031544 peptidyl-proline 3-dioxygenase activity(GO:0031544)
0.0 0.8 GO:0004012 phospholipid-translocating ATPase activity(GO:0004012)
0.0 1.9 GO:0003724 RNA helicase activity(GO:0003724) ATP-dependent RNA helicase activity(GO:0004004)
0.0 0.8 GO:0030515 snoRNA binding(GO:0030515)
0.0 0.2 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.2 GO:0050700 CARD domain binding(GO:0050700)
0.0 0.5 GO:0042800 histone methyltransferase activity (H3-K4 specific)(GO:0042800)
0.0 0.2 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.7 GO:0070182 DNA polymerase binding(GO:0070182)
0.0 0.2 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.0 0.4 GO:0055106 ubiquitin-protein transferase regulator activity(GO:0055106)
0.0 0.3 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.0 0.1 GO:0030627 pre-mRNA 5'-splice site binding(GO:0030627)
0.0 0.2 GO:0046790 virion binding(GO:0046790)
0.0 0.1 GO:0031755 endothelial differentiation G-protein coupled receptor binding(GO:0031753) Edg-2 lysophosphatidic acid receptor binding(GO:0031755)
0.0 0.4 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.4 GO:0008253 5'-nucleotidase activity(GO:0008253)
0.0 0.1 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.0 0.4 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.6 GO:0005385 zinc ion transmembrane transporter activity(GO:0005385)
0.0 0.3 GO:0010314 phosphatidylinositol-5-phosphate binding(GO:0010314)
0.0 0.9 GO:0042169 SH2 domain binding(GO:0042169)
0.0 0.8 GO:0004521 endoribonuclease activity(GO:0004521)
0.0 0.2 GO:0033038 bitter taste receptor activity(GO:0033038)
0.0 0.9 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.2 GO:0016423 tRNA (guanine) methyltransferase activity(GO:0016423)
0.0 0.2 GO:0015095 magnesium ion transmembrane transporter activity(GO:0015095)
0.0 1.2 GO:0015078 hydrogen ion transmembrane transporter activity(GO:0015078)
0.0 0.1 GO:0004128 cytochrome-b5 reductase activity, acting on NAD(P)H(GO:0004128)
0.0 0.3 GO:0043295 glutathione binding(GO:0043295) oligopeptide binding(GO:1900750)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 1.6 PID HDAC CLASSIII PATHWAY Signaling events mediated by HDAC Class III
0.0 0.5 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 2.0 PID AURORA B PATHWAY Aurora B signaling
0.0 1.0 PID INTEGRIN3 PATHWAY Beta3 integrin cell surface interactions
0.0 0.5 PID HIF2PATHWAY HIF-2-alpha transcription factor network
0.0 0.6 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.6 ST WNT BETA CATENIN PATHWAY Wnt/beta-catenin Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 6.3 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.1 1.5 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.1 0.9 REACTOME ABACAVIR TRANSPORT AND METABOLISM Genes involved in Abacavir transport and metabolism
0.0 0.6 REACTOME ER PHAGOSOME PATHWAY Genes involved in ER-Phagosome pathway
0.0 1.6 REACTOME KINESINS Genes involved in Kinesins
0.0 0.5 REACTOME P53 INDEPENDENT G1 S DNA DAMAGE CHECKPOINT Genes involved in p53-Independent G1/S DNA damage checkpoint
0.0 1.3 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.2 REACTOME BINDING AND ENTRY OF HIV VIRION Genes involved in Binding and entry of HIV virion
0.0 1.0 REACTOME SIGNAL REGULATORY PROTEIN SIRP FAMILY INTERACTIONS Genes involved in Signal regulatory protein (SIRP) family interactions
0.0 0.7 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.0 1.1 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.4 REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION Genes involved in Nef mediated downregulation of MHC class I complex cell surface expression
0.0 0.5 REACTOME AUTODEGRADATION OF CDH1 BY CDH1 APC C Genes involved in Autodegradation of Cdh1 by Cdh1:APC/C
0.0 0.7 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.6 REACTOME DEPOSITION OF NEW CENPA CONTAINING NUCLEOSOMES AT THE CENTROMERE Genes involved in Deposition of New CENPA-containing Nucleosomes at the Centromere
0.0 0.5 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.4 REACTOME NEGATIVE REGULATION OF THE PI3K AKT NETWORK Genes involved in Negative regulation of the PI3K/AKT network
0.0 0.2 REACTOME MEMBRANE BINDING AND TARGETTING OF GAG PROTEINS Genes involved in Membrane binding and targetting of GAG proteins
0.0 0.6 REACTOME PKA MEDIATED PHOSPHORYLATION OF CREB Genes involved in PKA-mediated phosphorylation of CREB
0.0 0.8 REACTOME BASIGIN INTERACTIONS Genes involved in Basigin interactions
0.0 0.7 REACTOME ACTIVATION OF ATR IN RESPONSE TO REPLICATION STRESS Genes involved in Activation of ATR in response to replication stress
0.0 0.3 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.8 REACTOME ION TRANSPORT BY P TYPE ATPASES Genes involved in Ion transport by P-type ATPases
0.0 0.3 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.0 0.5 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 0.3 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 0.2 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.9 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.6 REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL Genes involved in Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell
0.0 0.4 REACTOME TIGHT JUNCTION INTERACTIONS Genes involved in Tight junction interactions