Project

avrg: GFI1 WT vs 36n/n vs KD

Navigation
Downloads

Results for Hoxb1

Z-value: 0.75

Motif logo

logo of

Transcription factors associated with Hoxb1

Gene Symbol Gene ID Gene Info
Hoxb1
ENSMUSG00000018973.3 homeobox B1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Hoxb1mm39_v1_chr11_+_96256565_962565780.961.0e-02Click!

Activity profile of Hoxb1 motif

Sorted Z-values of Hoxb1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr10_+_127512933 0.60 ENSMUST00000118612.8
ENSMUST00000048099.5
Nemp1
nuclear envelope integral membrane protein 1
chr11_-_97913420 0.54 ENSMUST00000103144.10
ENSMUST00000017552.13
ENSMUST00000092736.11
ENSMUST00000107562.2
Cacnb1
calcium channel, voltage-dependent, beta 1 subunit
chr8_-_106198112 0.36 ENSMUST00000014990.13
Tppp3
tubulin polymerization-promoting protein family member 3
chrX_+_109857866 0.35 ENSMUST00000078229.5
Pou3f4
POU domain, class 3, transcription factor 4
chr10_-_12745109 0.33 ENSMUST00000218635.2
Utrn
utrophin
chr14_-_69740670 0.29 ENSMUST00000180059.3
ENSMUST00000179116.3
Gm16867
predicted gene, 16867
chr14_-_69522431 0.29 ENSMUST00000183882.2
ENSMUST00000037064.5
Slc25a37
solute carrier family 25, member 37
chr10_+_4216353 0.28 ENSMUST00000045730.7
Akap12
A kinase (PRKA) anchor protein (gravin) 12
chr2_+_124452194 0.28 ENSMUST00000051419.15
ENSMUST00000076335.12
ENSMUST00000078621.12
ENSMUST00000077847.12
Sema6d
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
chr8_+_108669276 0.27 ENSMUST00000220518.2
Zfhx3
zinc finger homeobox 3
chr8_+_121262528 0.23 ENSMUST00000120493.8
Gse1
genetic suppressor element 1, coiled-coil protein
chr14_+_50656083 0.22 ENSMUST00000216949.2
Olfr739
olfactory receptor 739
chr4_+_102971581 0.21 ENSMUST00000106858.8
Mier1
MEIR1 treanscription regulator
chr11_+_96256565 0.21 ENSMUST00000019117.3
Hoxb1
homeobox B1
chr19_-_5553804 0.21 ENSMUST00000189704.2
Nscme3l
NSE3 homolog, SMC5-SMC6 complex component like
chr12_+_38830081 0.20 ENSMUST00000095767.11
Etv1
ets variant 1
chr19_-_47452557 0.19 ENSMUST00000111800.4
Sh3pxd2a
SH3 and PX domains 2A
chr2_-_104324035 0.18 ENSMUST00000111124.8
Hipk3
homeodomain interacting protein kinase 3
chr9_-_91247809 0.17 ENSMUST00000034927.13
Zic1
zinc finger protein of the cerebellum 1
chr18_+_42644552 0.15 ENSMUST00000237602.2
ENSMUST00000236088.2
ENSMUST00000025375.15
Tcerg1
transcription elongation regulator 1 (CA150)
chr3_-_37286714 0.15 ENSMUST00000161015.2
ENSMUST00000029273.8
Il21
interleukin 21
chr2_+_119803230 0.15 ENSMUST00000229024.2
Mapkbp1
mitogen-activated protein kinase binding protein 1
chrX_+_165127688 0.15 ENSMUST00000112223.8
ENSMUST00000112224.8
ENSMUST00000112229.9
ENSMUST00000112228.8
ENSMUST00000112227.9
ENSMUST00000112226.3
Gpm6b
glycoprotein m6b
chr4_+_100633860 0.14 ENSMUST00000030257.15
ENSMUST00000097955.3
Cachd1
cache domain containing 1
chr5_-_107437427 0.13 ENSMUST00000031224.15
Tgfbr3
transforming growth factor, beta receptor III
chr5_-_138270995 0.13 ENSMUST00000161665.2
ENSMUST00000100530.8
ENSMUST00000161279.8
ENSMUST00000161647.8
Gal3st4
galactose-3-O-sulfotransferase 4
chr10_+_67021509 0.13 ENSMUST00000173689.8
Jmjd1c
jumonji domain containing 1C
chr4_+_43669266 0.12 ENSMUST00000107864.8
Tmem8b
transmembrane protein 8B
chr2_+_84670956 0.12 ENSMUST00000111625.2
Slc43a1
solute carrier family 43, member 1
chr9_+_78303059 0.11 ENSMUST00000113367.2
Ddx43
DEAD box helicase 43
chr11_+_85243970 0.11 ENSMUST00000108056.8
ENSMUST00000108061.8
ENSMUST00000108062.8
ENSMUST00000138423.8
ENSMUST00000092821.10
ENSMUST00000074875.11
Bcas3
breast carcinoma amplified sequence 3
chr6_-_136852792 0.10 ENSMUST00000032342.3
Mgp
matrix Gla protein
chr4_-_102971752 0.10 ENSMUST00000106868.4
Dnai4
dynein axonemal intermediate chain 4
chr18_-_56695333 0.10 ENSMUST00000066208.13
ENSMUST00000172734.8
Aldh7a1
aldehyde dehydrogenase family 7, member A1
chr6_+_142359099 0.09 ENSMUST00000126521.9
ENSMUST00000211094.2
Spx
spexin hormone
chr2_-_153371861 0.09 ENSMUST00000035346.14
Nol4l
nucleolar protein 4-like
chr2_-_90900525 0.08 ENSMUST00000153367.2
ENSMUST00000079976.10
Slc39a13
solute carrier family 39 (metal ion transporter), member 13
chr17_+_27160203 0.08 ENSMUST00000194598.6
Syngap1
synaptic Ras GTPase activating protein 1 homolog (rat)
chr2_-_165717697 0.08 ENSMUST00000153655.8
Zmynd8
zinc finger, MYND-type containing 8
chrX_-_7999009 0.08 ENSMUST00000130832.8
ENSMUST00000033506.13
ENSMUST00000115623.8
ENSMUST00000153839.2
Wdr13
WD repeat domain 13
chr2_+_119803180 0.07 ENSMUST00000066058.8
Mapkbp1
mitogen-activated protein kinase binding protein 1
chr2_-_90900628 0.07 ENSMUST00000111436.3
ENSMUST00000073575.12
Slc39a13
solute carrier family 39 (metal ion transporter), member 13
chr17_+_27160356 0.06 ENSMUST00000229490.2
ENSMUST00000201702.5
ENSMUST00000177932.7
ENSMUST00000201349.6
Syngap1
synaptic Ras GTPase activating protein 1 homolog (rat)
chr4_+_102971909 0.06 ENSMUST00000143417.8
Mier1
MEIR1 treanscription regulator
chr6_-_87510200 0.06 ENSMUST00000113637.9
ENSMUST00000071024.7
Arhgap25
Rho GTPase activating protein 25
chr9_-_21223631 0.05 ENSMUST00000115433.11
Ap1m2
adaptor protein complex AP-1, mu 2 subunit
chr1_-_135615831 0.05 ENSMUST00000190298.8
Nav1
neuron navigator 1
chr11_-_83189670 0.04 ENSMUST00000175741.8
ENSMUST00000176518.2
Pex12
peroxisomal biogenesis factor 12
chr16_-_97763780 0.04 ENSMUST00000232187.2
ENSMUST00000231263.2
ENSMUST00000052089.9
ENSMUST00000063605.15
ENSMUST00000113734.9
ENSMUST00000231560.2
ENSMUST00000232165.2
Zbtb21
C2cd2
zinc finger and BTB domain containing 21
C2 calcium-dependent domain containing 2
chr12_+_79255702 0.03 ENSMUST00000122227.8
Rdh12
retinol dehydrogenase 12
chr12_+_79255678 0.03 ENSMUST00000021548.12
Rdh12
retinol dehydrogenase 12
chr1_+_153541020 0.03 ENSMUST00000152114.8
ENSMUST00000111812.8
Rgs8
regulator of G-protein signaling 8
chr19_-_3625698 0.02 ENSMUST00000172362.3
ENSMUST00000025846.16
ENSMUST00000226109.2
ENSMUST00000113997.9
Ppp6r3
protein phosphatase 6, regulatory subunit 3
chr18_-_56695288 0.02 ENSMUST00000170309.8
Aldh7a1
aldehyde dehydrogenase family 7, member A1
chr11_+_76563281 0.02 ENSMUST00000056184.2
Bhlha9
basic helix-loop-helix family, member a9
chr1_-_9770434 0.02 ENSMUST00000088658.11
Mybl1
myeloblastosis oncogene-like 1
chr2_+_124452493 0.01 ENSMUST00000103239.10
ENSMUST00000103240.9
Sema6d
sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6D
chr19_-_41732104 0.01 ENSMUST00000025993.10
Slit1
slit guidance ligand 1
chr14_-_24054352 0.01 ENSMUST00000190339.2
Kcnma1
potassium large conductance calcium-activated channel, subfamily M, alpha member 1
chr1_-_157240138 0.01 ENSMUST00000078308.13
Rasal2
RAS protein activator like 2

Network of associatons between targets according to the STRING database.

First level regulatory network of Hoxb1

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.2 GO:0021570 rhombomere 4 development(GO:0021570)
0.1 0.3 GO:1904059 regulation of locomotor rhythm(GO:1904059)
0.0 0.3 GO:0007527 adult somatic muscle development(GO:0007527)
0.0 0.1 GO:0060938 transforming growth factor beta receptor complex assembly(GO:0007181) cardiac fibroblast cell differentiation(GO:0060935) cardiac fibroblast cell development(GO:0060936) epicardium-derived cardiac fibroblast cell differentiation(GO:0060938) epicardium-derived cardiac fibroblast cell development(GO:0060939)
0.0 0.2 GO:0007256 activation of JNKK activity(GO:0007256) negative regulation of defense response to bacterium(GO:1900425)
0.0 0.1 GO:0002729 positive regulation of natural killer cell cytokine production(GO:0002729)
0.0 0.1 GO:0051581 negative regulation of neurotransmitter uptake(GO:0051581) regulation of serotonin uptake(GO:0051611) negative regulation of serotonin uptake(GO:0051612)
0.0 0.3 GO:0031937 positive regulation of chromatin silencing(GO:0031937)
0.0 0.3 GO:2001054 negative regulation of mesenchymal cell apoptotic process(GO:2001054)
0.0 0.3 GO:0010739 positive regulation of protein kinase A signaling(GO:0010739)
0.0 0.2 GO:0072675 osteoclast fusion(GO:0072675)
0.0 0.1 GO:1903756 regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903756) negative regulation of transcription from RNA polymerase II promoter by histone modification(GO:1903758)
0.0 0.1 GO:0030718 germ-line stem cell population maintenance(GO:0030718)
0.0 0.1 GO:1904306 positive regulation of gastro-intestinal system smooth muscle contraction(GO:1904306)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0034673 inhibin-betaglycan-ActRII complex(GO:0034673)
0.0 0.4 GO:0097427 microtubule bundle(GO:0097427)
0.0 0.3 GO:0070938 contractile ring(GO:0070938)
0.0 0.0 GO:1990415 Pex17p-Pex14p docking complex(GO:1990415) peroxisomal importomer complex(GO:1990429)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.1 GO:0010698 acetyltransferase activator activity(GO:0010698)
0.0 0.1 GO:0008802 betaine-aldehyde dehydrogenase activity(GO:0008802)
0.0 0.1 GO:0005134 interleukin-2 receptor binding(GO:0005134)
0.0 0.1 GO:0050694 galactose 3-O-sulfotransferase activity(GO:0050694)
0.0 0.5 GO:0008331 high voltage-gated calcium channel activity(GO:0008331)
0.0 0.3 GO:0015093 ferrous iron transmembrane transporter activity(GO:0015093)
0.0 0.3 GO:0030215 semaphorin receptor binding(GO:0030215)
0.0 0.2 GO:0016176 superoxide-generating NADPH oxidase activator activity(GO:0016176)
0.0 0.1 GO:0005114 type II transforming growth factor beta receptor binding(GO:0005114)
0.0 0.3 GO:0003680 AT DNA binding(GO:0003680)
0.0 0.3 GO:0008179 adenylate cyclase binding(GO:0008179)

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.3 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions