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avrg: GFI1 WT vs 36n/n vs KD

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Results for Hoxd12

Z-value: 1.22

Motif logo

Transcription factors associated with Hoxd12

Gene Symbol Gene ID Gene Info
ENSMUSG00000001823.6 homeobox D12

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Hoxd12mm39_v1_chr2_+_74505350_74505357-0.642.5e-01Click!

Activity profile of Hoxd12 motif

Sorted Z-values of Hoxd12 motif

Promoter Log-likelihood Transcript Gene Gene Info
chrX_+_55493325 0.94 ENSMUST00000079663.7
predicted gene 2174
chr12_-_73093953 0.93 ENSMUST00000050029.8
sine oculis-related homeobox 1
chr10_-_35587888 0.91 ENSMUST00000080898.4
S-adenosylmethionine decarboxylase 2
chr13_+_94954202 0.81 ENSMUST00000220825.2
tubulin cofactor A
chr4_-_136329953 0.73 ENSMUST00000105847.8
ENSMUST00000116273.9
lysine (K)-specific demethylase 1A
chr19_+_24853039 0.70 ENSMUST00000073080.7
predicted gene 10053
chr1_-_45542442 0.69 ENSMUST00000086430.5
collagen, type V, alpha 2
chr8_+_70354828 0.66 ENSMUST00000050373.7
testis-specific serine kinase 6
chr14_-_31503869 0.65 ENSMUST00000227089.2
ankyrin repeat domain 28
chr4_-_154721288 0.63 ENSMUST00000030902.13
ENSMUST00000105637.8
ENSMUST00000070313.14
ENSMUST00000105636.8
ENSMUST00000105638.9
ENSMUST00000097759.9
ENSMUST00000124771.2
PR domain containing 16
chr17_-_71305003 0.59 ENSMUST00000024846.13
ENSMUST00000232766.2
myosin, light chain 12A, regulatory, non-sarcomeric
chr4_-_87951565 0.57 ENSMUST00000078090.12
myeloid/lymphoid or mixed-lineage leukemia; translocated to, 3
chr10_-_37014859 0.57 ENSMUST00000092584.6
myristoylated alanine rich protein kinase C substrate
chr10_+_4561974 0.56 ENSMUST00000105590.8
ENSMUST00000067086.14
estrogen receptor 1 (alpha)
chr8_-_70355208 0.55 ENSMUST00000110167.5
NADH:ubiquinone oxidoreductase subunit A13
chr5_+_31212165 0.55 ENSMUST00000202795.4
ENSMUST00000201182.4
ENSMUST00000200953.4
carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
chr17_+_35278011 0.55 ENSMUST00000007255.13
ENSMUST00000174493.8
dimethylarginine dimethylaminohydrolase 2
chr9_+_120758282 0.53 ENSMUST00000130466.8
catenin (cadherin associated protein), beta 1
chr4_-_92079986 0.52 ENSMUST00000123179.2
predicted gene 12666
chr7_+_80863314 0.52 ENSMUST00000026672.8
phosphodiesterase 8A
chr5_+_31212110 0.51 ENSMUST00000013773.12
ENSMUST00000201838.4
carbamoyl-phosphate synthetase 2, aspartate transcarbamylase, and dihydroorotase
chrX_-_133442596 0.48 ENSMUST00000054213.5
translocase of inner mitochondrial membrane 8A1
chr3_-_19217174 0.48 ENSMUST00000029125.10
armadillo repeat containing 1
chr18_+_35347983 0.47 ENSMUST00000235449.2
ENSMUST00000235269.2
catenin (cadherin associated protein), alpha 1
chr11_-_102210568 0.44 ENSMUST00000173870.8
upstream binding transcription factor, RNA polymerase I
chr1_-_44157916 0.43 ENSMUST00000027213.14
ENSMUST00000065767.9
protein O-glucosyltransferase 2
chr5_-_65855511 0.41 ENSMUST00000201948.4
PDS5 cohesin associated factor A
chrX_+_139357362 0.40 ENSMUST00000033809.4
phosphoribosyl pyrophosphate synthetase 1
chr19_+_60744385 0.38 ENSMUST00000088237.6
nanos C2HC-type zinc finger 1
chr16_-_35589726 0.37 ENSMUST00000023554.9
solute carrier family 49 member 4
chr6_-_119365632 0.37 ENSMUST00000169744.8
adiponectin receptor 2
chr1_-_165762469 0.36 ENSMUST00000069609.12
ENSMUST00000111427.9
ENSMUST00000111426.11
POU domain, class 2, transcription factor 1
chr4_-_82768958 0.35 ENSMUST00000139401.2
zinc finger, DHHC domain containing 21
chr12_+_55883101 0.33 ENSMUST00000059250.8
breast cancer metastasis-suppressor 1-like
chr7_-_100232276 0.31 ENSMUST00000152876.3
ENSMUST00000150042.8
ENSMUST00000132888.9
mitochondrial ribosomal protein L48
chr5_-_24235646 0.30 ENSMUST00000197617.5
ENSMUST00000030849.13
family with sequence similarity 126, member A
chrX_-_71961890 0.30 ENSMUST00000152200.2
centrin 2
chr7_+_30264835 0.29 ENSMUST00000043850.14
IGF-like family receptor 1
chr10_+_43400074 0.29 ENSMUST00000057649.8
ENSMUST00000216543.2
predicted gene 9803
chr15_-_8740218 0.28 ENSMUST00000005493.14
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr6_+_125192514 0.28 ENSMUST00000032487.14
ENSMUST00000100942.9
ENSMUST00000063588.11
vesicle-associated membrane protein 1
chr13_+_25127127 0.27 ENSMUST00000021773.13
glycosylphosphatidylinositol specific phospholipase D1
chr1_-_46927230 0.26 ENSMUST00000185520.2
solute carrier family 39 (zinc transporter), member 10
chr5_-_148489593 0.26 ENSMUST00000201595.4
ENSMUST00000164904.2
ubiquitin-like 3
chr9_-_110453427 0.26 ENSMUST00000196876.2
ENSMUST00000035069.14
neurotrophin receptor associated death domain
chr11_+_31823096 0.26 ENSMUST00000155278.2
cytoplasmic polyadenylation element binding protein 4
chr17_+_6025861 0.26 ENSMUST00000142409.8
ENSMUST00000061091.14
synaptojanin 2
chr1_-_171854818 0.26 ENSMUST00000138714.2
ENSMUST00000027837.13
ENSMUST00000111264.8
VANGL planar cell polarity 2
chr13_-_43632368 0.25 ENSMUST00000222651.2
RAN binding protein 9
chr2_+_73102269 0.24 ENSMUST00000090813.6
trans-acting transcription factor 9
chr1_-_128030148 0.24 ENSMUST00000086614.12
zinc finger, RAN-binding domain containing 3
chrM_+_7758 0.24 ENSMUST00000082407.1
mitochondrially encoded ATP synthase 8
chr4_-_141412910 0.23 ENSMUST00000105782.2
regulatory solute carrier protein, family 1, member 1
chr19_-_6964988 0.23 ENSMUST00000130048.8
ENSMUST00000025914.7
vascular endothelial growth factor B
chr3_-_88317601 0.22 ENSMUST00000193338.6
ENSMUST00000056370.13
polyamine-modulated factor 1
chr13_-_21826688 0.21 ENSMUST00000205631.3
olfactory receptor 11
chr19_+_56414114 0.21 ENSMUST00000238892.2
caspase 7
chr17_+_6026015 0.21 ENSMUST00000115790.8
synaptojanin 2
chr10_+_87926932 0.21 ENSMUST00000048621.8
pro-melanin-concentrating hormone
chrX_-_156351979 0.21 ENSMUST00000065806.5
Yy2 transcription factor
chr18_+_12261798 0.20 ENSMUST00000025270.8
RIO kinase 3
chr11_-_109363406 0.20 ENSMUST00000168740.3
solute carrier family 16 (monocarboxylic acid transporters), member 6
chr10_+_45453907 0.20 ENSMUST00000037044.13
HECT domain and ankyrin repeat containing, E3 ubiquitin protein ligase 1
chr1_-_37535202 0.20 ENSMUST00000143636.8
mannoside acetylglucosaminyltransferase 4, isoenzyme A
chr5_-_25047577 0.19 ENSMUST00000030787.9
Ras homolog enriched in brain
chr15_+_81629258 0.19 ENSMUST00000109554.3
ENSMUST00000230946.2
zinc finger CCCH type containing 7B
chr10_+_116013256 0.18 ENSMUST00000155606.8
ENSMUST00000128399.2
protein tyrosine phosphatase, receptor type, R
chr8_-_47805383 0.18 ENSMUST00000110367.10
storkhead box 2
chr11_-_118246566 0.18 ENSMUST00000155707.3
tissue inhibitor of metalloproteinase 2
chr15_-_34356567 0.17 ENSMUST00000179647.2
RIKEN cDNA 9430069I07 gene
chr3_+_66893280 0.17 ENSMUST00000161726.2
ENSMUST00000160504.2
arginine/serine-rich coiled-coil 1
chr5_-_138185686 0.17 ENSMUST00000110936.8
TATA-box binding protein associated factor 6
chr19_-_43741363 0.16 ENSMUST00000045562.6
cytochrome c oxidase assembly protein 15
chr19_+_53517528 0.16 ENSMUST00000038287.7
dual specificity phosphatase 5
chr11_-_109364046 0.15 ENSMUST00000070872.13
solute carrier family 16 (monocarboxylic acid transporters), member 6
chr12_+_103524690 0.15 ENSMUST00000187155.7
protein phosphatase 4, regulatory subunit 4
chr17_-_52133594 0.15 ENSMUST00000129667.8
ENSMUST00000169480.8
ENSMUST00000148559.2
special AT-rich sequence binding protein 1
chr10_+_86599836 0.15 ENSMUST00000218802.2
predicted gene, 49358
chr14_+_79086665 0.14 ENSMUST00000227255.2
von Willebrand factor A domain containing 8
chr5_+_143864993 0.14 ENSMUST00000172367.3
predicted gene, 42421
chrM_+_7779 0.13 ENSMUST00000082408.1
mitochondrially encoded ATP synthase 6
chr3_+_67799510 0.13 ENSMUST00000063263.5
ENSMUST00000182006.4
IQ motif containing J
Iqcj and Schip1 fusion protein
chr15_+_25774070 0.13 ENSMUST00000125667.3
myosin X
chr15_-_8739893 0.12 ENSMUST00000157065.2
solute carrier family 1 (glial high affinity glutamate transporter), member 3
chr4_-_133695264 0.12 ENSMUST00000102553.11
high mobility group nucleosomal binding domain 2
chr1_+_128069716 0.12 ENSMUST00000187557.2
R3H domain containing 1
chr19_-_47452840 0.11 ENSMUST00000081619.10
SH3 and PX domains 2A
chr10_+_42459772 0.11 ENSMUST00000105497.8
ENSMUST00000144806.8
osteopetrosis associated transmembrane protein 1
chr2_+_57887896 0.11 ENSMUST00000112616.8
ENSMUST00000166729.2
polypeptide N-acetylgalactosaminyltransferase 5
chr14_+_31807760 0.11 ENSMUST00000170600.8
ENSMUST00000168986.7
ENSMUST00000169649.2
oxidoreductase NAD-binding domain containing 1
chr3_-_87676239 0.11 ENSMUST00000173184.2
ENSMUST00000172621.8
ENSMUST00000174759.8
ENSMUST00000172590.8
ENSMUST00000079083.12
platelet endothelial aggregation receptor 1
chr6_+_29694181 0.10 ENSMUST00000046750.14
ENSMUST00000115250.4
tetraspanin 33
chr14_+_79086492 0.10 ENSMUST00000040990.7
von Willebrand factor A domain containing 8
chr10_+_26698556 0.10 ENSMUST00000135866.2
Rho GTPase activating protein 18
chr1_-_57008986 0.10 ENSMUST00000176759.2
ENSMUST00000177424.2
special AT-rich sequence binding protein 2
chr10_-_80257681 0.10 ENSMUST00000156244.2
transcription factor 3
chr10_-_107321938 0.09 ENSMUST00000000445.2
myogenic factor 5
chr10_+_116013122 0.09 ENSMUST00000148731.8
protein tyrosine phosphatase, receptor type, R
chr16_-_50252703 0.09 ENSMUST00000066037.13
ENSMUST00000089399.11
ENSMUST00000089404.10
ENSMUST00000138166.8
bobby sox HMG box containing
chr5_-_74692327 0.09 ENSMUST00000072857.13
ENSMUST00000113542.9
ENSMUST00000151474.3
Sec1 family domain containing 2
chr18_+_37864045 0.08 ENSMUST00000192535.2
protocadherin gamma subfamily B, 5
chr4_+_31964082 0.08 ENSMUST00000037607.11
ENSMUST00000080933.13
ENSMUST00000108183.8
ENSMUST00000108184.3
mitogen-activated protein kinase kinase kinase 7
chr4_-_82423985 0.08 ENSMUST00000107245.9
ENSMUST00000107246.2
nuclear factor I/B
chr1_-_74639723 0.07 ENSMUST00000127938.8
ENSMUST00000154874.8
ring finger protein 25
chr5_+_107645626 0.07 ENSMUST00000152474.8
ENSMUST00000060553.8
BTB (POZ) domain containing 8
chr9_-_14815228 0.06 ENSMUST00000034409.14
ENSMUST00000117620.8
IZUMO1 receptor, JUNO
chr17_+_38104420 0.06 ENSMUST00000216051.3
olfactory receptor 123
chr7_-_5017642 0.06 ENSMUST00000207412.2
ENSMUST00000077385.15
ENSMUST00000165320.3
Flt3 interacting zinc finger protein 1
chr9_+_110948492 0.05 ENSMUST00000217341.3
leucine rich repeat (in FLII) interacting protein 2
chr14_+_65595838 0.05 ENSMUST00000224623.2
zinc finger protein 395
chr17_+_38104635 0.05 ENSMUST00000214770.3
olfactory receptor 123
chr3_+_122213420 0.05 ENSMUST00000029766.9
breast cancer anti-estrogen resistance 3
chr2_+_85648823 0.05 ENSMUST00000214416.2
olfactory receptor 1018
chr19_-_50667079 0.05 ENSMUST00000209413.2
ENSMUST00000072685.13
ENSMUST00000164039.9
sortilin-related VPS10 domain containing receptor 1
chr11_-_99228756 0.04 ENSMUST00000100482.3
keratin 26
chr10_-_25076008 0.04 ENSMUST00000100012.3
A kinase (PRKA) anchor protein 7
chr10_-_28862289 0.04 ENSMUST00000152363.8
ENSMUST00000015663.7
RIKEN cDNA 2310057J18 gene
chr2_-_86216760 0.04 ENSMUST00000102631.2
olfactory receptor 1058
chr4_+_136012019 0.04 ENSMUST00000130223.8
zinc finger protein 46
chrX_+_55824797 0.04 ENSMUST00000114773.10
four and a half LIM domains 1
chrX_+_95498965 0.03 ENSMUST00000033553.14
hephaestin
chr3_+_66893031 0.03 ENSMUST00000046542.13
ENSMUST00000162693.8
arginine/serine-rich coiled-coil 1
chr3_+_121838076 0.03 ENSMUST00000013995.13
ATP-binding cassette, sub-family A (ABC1), member 4
chr4_+_136011969 0.03 ENSMUST00000144217.8
zinc finger protein 46
chr16_-_89305201 0.03 ENSMUST00000056118.4
keratin associated protein 7-1
chr17_-_91400142 0.03 ENSMUST00000160800.9
neurexin I
chr16_+_11223512 0.03 ENSMUST00000096273.9
sorting nexin 29
chrX_-_42363663 0.03 ENSMUST00000016294.8
teneurin transmembrane protein 1
chr3_-_154760978 0.03 ENSMUST00000064076.6
TNNI3 interacting kinase
chr14_-_68771138 0.03 ENSMUST00000022640.8
a disintegrin and metallopeptidase domain 7
chr3_-_154036180 0.03 ENSMUST00000177846.8
LIM homeobox protein 8
chr4_-_83203388 0.03 ENSMUST00000150522.8
tetratricopeptide repeat domain 39B
chr2_-_66240408 0.03 ENSMUST00000112366.8
sodium channel, voltage-gated, type I, alpha
chr5_+_20112500 0.03 ENSMUST00000101558.10
membrane associated guanylate kinase, WW and PDZ domain containing 2
chr2_+_36883839 0.02 ENSMUST00000213218.2
olfactory receptor 357
chr10_+_89906956 0.02 ENSMUST00000183109.2
ankyrin repeat and sterile alpha motif domain containing 1B
chr2_-_131194754 0.02 ENSMUST00000059372.11
ring finger protein 24
chr17_-_38442081 0.02 ENSMUST00000087128.2
olfactory receptor 132
chr10_+_129611696 0.02 ENSMUST00000059891.3
ENSMUST00000218237.2
olfactory receptor 809
chr16_-_56616186 0.02 ENSMUST00000023437.5
adhesion G protein-coupled receptor G7
chr5_-_86437119 0.02 ENSMUST00000196462.2
ENSMUST00000059424.10
transmembrane protease, serine 11c
chr10_-_128996851 0.02 ENSMUST00000078914.3
olfactory receptor 771
chr10_+_52267702 0.02 ENSMUST00000067085.7
nephrocan
chrX_-_142716085 0.02 ENSMUST00000087313.10
doublecortin
chr16_-_58850641 0.02 ENSMUST00000216415.2
ENSMUST00000206463.3
olfactory receptor 186
chr11_-_101785181 0.02 ENSMUST00000057054.8
mesenchyme homeobox 1
chr14_+_53048391 0.02 ENSMUST00000103646.5
T cell receptor alpha variable 10D
chrX_-_103244784 0.02 ENSMUST00000118314.8
neurite extension and migration factor
chr14_-_48900192 0.02 ENSMUST00000122009.8
orthodenticle homeobox 2
chr17_-_36207965 0.02 ENSMUST00000150056.2
ENSMUST00000156817.2
ENSMUST00000146451.8
ENSMUST00000148482.8
RIKEN cDNA 2310061I04 gene
chr10_-_38998272 0.02 ENSMUST00000136546.8
family with sequence similarity 229, member B
chr9_-_123778334 0.02 ENSMUST00000071404.5
chemokine (C-C motif) receptor 1-like 1
chr18_-_3281727 0.02 ENSMUST00000154705.8
ENSMUST00000151084.8
cAMP responsive element modulator
chr10_+_93476903 0.02 ENSMUST00000020204.5
netrin 4
chr6_-_24168082 0.02 ENSMUST00000031713.9
solute carrier family 13 (sodium/sulfate symporters), member 1
chr19_+_40078132 0.02 ENSMUST00000068094.13
ENSMUST00000080171.3
cytochrome P450, family 2, subfamily c, polypeptide 50
chr4_+_109092459 0.02 ENSMUST00000106631.9
calreticulin 4
chr4_-_96673423 0.02 ENSMUST00000107071.2
predicted gene 12695
chr9_-_14815050 0.02 ENSMUST00000148155.2
ENSMUST00000121116.8
IZUMO1 receptor, JUNO
chr5_+_18167547 0.02 ENSMUST00000030561.9
guanine nucleotide binding protein, alpha transducing 3
chr2_-_87805007 0.01 ENSMUST00000099840.2
olfactory receptor 74
chr11_-_42070517 0.01 ENSMUST00000206105.2
ENSMUST00000153147.3
gamma-aminobutyric acid (GABA) A receptor, subunit alpha 1
chr17_+_71326542 0.01 ENSMUST00000179759.3
myomesin 1
chr3_-_72875187 0.01 ENSMUST00000167334.8
sucrase isomaltase (alpha-glucosidase)
chr2_+_65676176 0.01 ENSMUST00000053910.10
cysteine-serine-rich nuclear protein 3
chr15_-_101422054 0.01 ENSMUST00000230067.3
predicted gene, 49425
chr4_+_148085179 0.01 ENSMUST00000103230.5
natriuretic peptide type A
chr15_+_39255185 0.01 ENSMUST00000228839.2
regulating synaptic membrane exocytosis 2
chr1_+_81054992 0.01 ENSMUST00000068275.12
ENSMUST00000113494.9
neuronal tyrosine-phophorylated phosphoinositide 3-kinase adaptor 2
chr1_+_81054921 0.01 ENSMUST00000123720.8
neuronal tyrosine-phophorylated phosphoinositide 3-kinase adaptor 2
chr17_+_31652029 0.01 ENSMUST00000136384.9
phosphodiesterase 9A
chr1_-_28819331 0.01 ENSMUST00000059937.5
predicted gene 597
chr3_+_40978804 0.01 ENSMUST00000099121.10
La ribonucleoprotein domain family, member 1B
chr2_-_86521317 0.01 ENSMUST00000099877.2
olfactory receptor 1087
chr6_-_132934882 0.01 ENSMUST00000082085.5
taste receptor, type 2, member 131
chr6_+_83063348 0.01 ENSMUST00000041265.4
ladybird homeobox 2
chr11_-_99996452 0.01 ENSMUST00000107416.3
keratin 36
chr7_-_102408573 0.01 ENSMUST00000210453.3
ENSMUST00000232246.3
ENSMUST00000239110.2
ENSMUST00000060187.15
ENSMUST00000168007.3
olfactory receptor 560
olfactory receptor 78
chr17_+_31652073 0.01 ENSMUST00000237363.2
phosphodiesterase 9A
chr5_+_138185747 0.01 ENSMUST00000110934.9
canopy FGF signaling regulator 4
chr18_-_84854841 0.01 ENSMUST00000236689.2
predicted gene, 17266
chr10_-_116732813 0.01 ENSMUST00000048229.9
myelin regulatory factor-like
chr10_+_23814470 0.01 ENSMUST00000079134.5
trace amine-associated receptor 2
chr2_-_140513382 0.01 ENSMUST00000110057.3
fibronectin leucine rich transmembrane protein 3
chr3_-_122828592 0.01 ENSMUST00000029761.14
myozenin 2
chr14_-_118289557 0.01 ENSMUST00000022725.4
dopachrome tautomerase
chr8_+_45960931 0.01 ENSMUST00000171337.10
ENSMUST00000067107.15
sorbin and SH3 domain containing 2
chrX_-_103244728 0.01 ENSMUST00000056502.7
neurite extension and migration factor
chr18_+_44249254 0.01 ENSMUST00000212114.2
predicted gene, 37797
chr2_-_35994819 0.01 ENSMUST00000148852.4
LIM homeobox protein 6
chr18_-_3281752 0.01 ENSMUST00000140332.8
ENSMUST00000147138.8
cAMP responsive element modulator
chr6_+_15185399 0.01 ENSMUST00000115474.8
ENSMUST00000115472.8
ENSMUST00000031545.14
forkhead box P2
chr2_+_111327525 0.01 ENSMUST00000121345.4
olfactory receptor 1291, pseudogene 1
chr7_+_89780785 0.01 ENSMUST00000208684.2
phosphatidylinositol binding clathrin assembly protein
chr5_+_88603847 0.01 ENSMUST00000198265.5
ENSMUST00000031226.9
ameloblastin
chr5_+_88032867 0.01 ENSMUST00000129757.9
odontogenic, ameloblast asssociated
chr8_+_57774010 0.01 ENSMUST00000040104.5
heart and neural crest derivatives expressed 2
chr2_-_140513320 0.01 ENSMUST00000056760.4
fibronectin leucine rich transmembrane protein 3
chr3_-_26386609 0.01 ENSMUST00000193603.6
neuroligin 1
chr5_-_69699965 0.00 ENSMUST00000031045.10
Yip1 domain family, member 7

Network of associatons between targets according to the STRING database.

First level regulatory network of Hoxd12

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 0.9 GO:0006597 spermine biosynthetic process(GO:0006597)
0.3 0.9 GO:2000729 positive regulation of mesenchymal cell proliferation involved in ureter development(GO:2000729)
0.2 0.4 GO:0046100 hypoxanthine metabolic process(GO:0046100) hypoxanthine biosynthetic process(GO:0046101)
0.2 0.7 GO:0046098 guanine metabolic process(GO:0046098)
0.2 0.5 GO:1904793 regulation of chromatin-mediated maintenance of transcription(GO:1904499) positive regulation of chromatin-mediated maintenance of transcription(GO:1904501) regulation of euchromatin binding(GO:1904793)
0.2 0.7 GO:1903225 negative regulation of endodermal cell differentiation(GO:1903225)
0.2 0.8 GO:0007023 post-chaperonin tubulin folding pathway(GO:0007023)
0.2 1.1 GO:0019856 'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
0.1 0.4 GO:0098749 cerebellar neuron development(GO:0098749)
0.1 0.6 GO:0060523 prostate epithelial cord elongation(GO:0060523)
0.1 0.6 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.1 0.3 GO:0060448 dichotomous subdivision of terminal units involved in lung branching(GO:0060448)
0.1 0.4 GO:0043490 malate-aspartate shuttle(GO:0043490)
0.1 0.5 GO:2001045 response to indole-3-methanol(GO:0071680) cellular response to indole-3-methanol(GO:0071681) negative regulation of integrin-mediated signaling pathway(GO:2001045)
0.1 0.4 GO:0071699 olfactory placode formation(GO:0030910) olfactory placode development(GO:0071698) olfactory placode morphogenesis(GO:0071699)
0.1 0.3 GO:0006507 GPI anchor release(GO:0006507) regulation of high-density lipoprotein particle clearance(GO:0010982)
0.1 0.6 GO:0061042 vascular wound healing(GO:0061042)
0.0 0.2 GO:0048478 replication fork protection(GO:0048478)
0.0 0.3 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.0 0.4 GO:0006362 transcription elongation from RNA polymerase I promoter(GO:0006362)
0.0 0.2 GO:0072734 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.0 0.5 GO:0006527 arginine catabolic process(GO:0006527)
0.0 0.2 GO:0032227 negative regulation of synaptic transmission, dopaminergic(GO:0032227)
0.0 0.7 GO:0035092 sperm chromatin condensation(GO:0035092)
0.0 0.6 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.0 0.1 GO:0080163 regulation of protein serine/threonine phosphatase activity(GO:0080163)
0.0 0.2 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.0 0.4 GO:0018231 peptidyl-L-cysteine S-palmitoylation(GO:0018230) peptidyl-S-diacylglycerol-L-cysteine biosynthetic process from peptidyl-cysteine(GO:0018231)
0.0 0.6 GO:2000096 positive regulation of Wnt signaling pathway, planar cell polarity pathway(GO:2000096)
0.0 0.3 GO:0050861 positive regulation of B cell receptor signaling pathway(GO:0050861)
0.0 0.3 GO:2000766 negative regulation of cytoplasmic translation(GO:2000766)
0.0 0.5 GO:0048312 intracellular distribution of mitochondria(GO:0048312)
0.0 0.6 GO:0051764 actin crosslink formation(GO:0051764)
0.0 0.2 GO:2000074 regulation of type B pancreatic cell development(GO:2000074)
0.0 0.0 GO:2000795 negative regulation of epithelial cell proliferation involved in lung morphogenesis(GO:2000795)
0.0 0.3 GO:0035493 SNARE complex assembly(GO:0035493)
0.0 0.1 GO:0002326 B cell lineage commitment(GO:0002326)
0.0 0.1 GO:0097343 ripoptosome assembly(GO:0097343) ripoptosome assembly involved in necroptotic process(GO:1901026)
0.0 0.1 GO:0048743 positive regulation of skeletal muscle fiber development(GO:0048743)
0.0 0.5 GO:1903206 negative regulation of hydrogen peroxide-induced cell death(GO:1903206)
0.0 0.4 GO:0007064 mitotic sister chromatid cohesion(GO:0007064)
0.0 0.1 GO:0043654 recognition of apoptotic cell(GO:0043654)
0.0 0.1 GO:0035660 MyD88-dependent toll-like receptor 4 signaling pathway(GO:0035660)
0.0 0.4 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0005588 collagen type V trimer(GO:0005588)
0.1 0.4 GO:0002189 ribose phosphate diphosphokinase complex(GO:0002189)
0.1 0.6 GO:0042585 germinal vesicle(GO:0042585)
0.1 0.3 GO:0060187 cell pole(GO:0060187)
0.1 0.6 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.1 0.3 GO:0071942 XPC complex(GO:0071942)
0.1 0.5 GO:0034750 Scrib-APC-beta-catenin complex(GO:0034750)
0.0 0.2 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.0 0.3 GO:0070820 tertiary granule(GO:0070820)
0.0 0.5 GO:0016342 catenin complex(GO:0016342)
0.0 0.5 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.0 0.4 GO:0045263 proton-transporting ATP synthase complex, coupling factor F(o)(GO:0045263)
0.0 0.2 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.3 GO:0005641 nuclear envelope lumen(GO:0005641)
0.0 0.7 GO:1990391 DNA repair complex(GO:1990391)
0.0 0.6 GO:0016460 myosin II complex(GO:0016460)
0.0 0.3 GO:0070822 Sin3-type complex(GO:0070822)
0.0 0.6 GO:0016235 aggresome(GO:0016235)
0.0 0.6 GO:0045271 mitochondrial respiratory chain complex I(GO:0005747) NADH dehydrogenase complex(GO:0030964) respiratory chain complex I(GO:0045271)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.1 GO:0004087 carbamoyl-phosphate synthase (ammonia) activity(GO:0004087) carbamoyl-phosphate synthase (glutamine-hydrolyzing) activity(GO:0004088)
0.2 0.6 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798) RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.1 0.7 GO:0034648 histone demethylase activity (H3-dimethyl-K4 specific)(GO:0034648)
0.1 0.9 GO:0019808 polyamine binding(GO:0019808)
0.1 0.4 GO:0004749 ribose phosphate diphosphokinase activity(GO:0004749)
0.1 0.2 GO:0043183 vascular endothelial growth factor receptor 1 binding(GO:0043183)
0.1 0.4 GO:0097003 adipokinetic hormone receptor activity(GO:0097003)
0.1 0.4 GO:0001165 RNA polymerase I upstream control element sequence-specific DNA binding(GO:0001165)
0.1 0.4 GO:0015501 glutamate:sodium symporter activity(GO:0015501)
0.1 0.5 GO:0016813 hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines(GO:0016813)
0.0 0.3 GO:0032795 heterotrimeric G-protein binding(GO:0032795)
0.0 0.5 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439)
0.0 0.5 GO:0045294 alpha-catenin binding(GO:0045294)
0.0 0.3 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.0 0.3 GO:0004630 phospholipase D activity(GO:0004630)
0.0 0.2 GO:0089720 caspase binding(GO:0089720)
0.0 0.9 GO:0001223 transcription coactivator binding(GO:0001223)
0.0 0.2 GO:0036310 annealing helicase activity(GO:0036310)
0.0 0.5 GO:0045295 gamma-catenin binding(GO:0045295)
0.0 0.2 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.2 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.0 0.3 GO:0000900 translation repressor activity, nucleic acid binding(GO:0000900)
0.0 0.2 GO:0043522 leucine zipper domain binding(GO:0043522)
0.0 0.7 GO:0005201 extracellular matrix structural constituent(GO:0005201)
0.0 0.8 GO:0048487 beta-tubulin binding(GO:0048487)
0.0 0.1 GO:0070644 vitamin D response element binding(GO:0070644)
0.0 0.5 GO:0004115 3',5'-cyclic-AMP phosphodiesterase activity(GO:0004115)
0.0 0.2 GO:0017162 aryl hydrocarbon receptor binding(GO:0017162)
0.0 0.0 GO:0090555 phosphatidylethanolamine-translocating ATPase activity(GO:0090555)
0.0 0.4 GO:0019706 protein-cysteine S-palmitoyltransferase activity(GO:0019706) protein-cysteine S-acyltransferase activity(GO:0019707)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.2 PID VEGF VEGFR PATHWAY VEGF and VEGFR signaling network
0.0 1.0 PID NECTIN PATHWAY Nectin adhesion pathway
0.0 0.9 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.7 NABA COLLAGENS Genes encoding collagen proteins
0.0 1.5 PID MYC ACTIV PATHWAY Validated targets of C-MYC transcriptional activation

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.0 0.6 REACTOME REGULATION OF INSULIN SECRETION BY ACETYLCHOLINE Genes involved in Regulation of Insulin Secretion by Acetylcholine
0.0 0.8 REACTOME POST CHAPERONIN TUBULIN FOLDING PATHWAY Genes involved in Post-chaperonin tubulin folding pathway
0.0 1.1 REACTOME PYRIMIDINE METABOLISM Genes involved in Pyrimidine metabolism
0.0 1.0 REACTOME ADHERENS JUNCTIONS INTERACTIONS Genes involved in Adherens junctions interactions
0.0 0.4 REACTOME RNA POL I PROMOTER OPENING Genes involved in RNA Polymerase I Promoter Opening
0.0 0.2 REACTOME VEGF LIGAND RECEPTOR INTERACTIONS Genes involved in VEGF ligand-receptor interactions
0.0 0.3 REACTOME PROTEOLYTIC CLEAVAGE OF SNARE COMPLEX PROTEINS Genes involved in Proteolytic cleavage of SNARE complex proteins
0.0 0.2 REACTOME REGULATION OF RHEB GTPASE ACTIVITY BY AMPK Genes involved in Regulation of Rheb GTPase activity by AMPK
0.0 0.4 REACTOME RNA POL III TRANSCRIPTION INITIATION FROM TYPE 3 PROMOTER Genes involved in RNA Polymerase III Transcription Initiation From Type 3 Promoter
0.0 0.7 REACTOME NCAM1 INTERACTIONS Genes involved in NCAM1 interactions