Project

avrg: GFI1 WT vs 36n/n vs KD

Navigation
Downloads

Results for Hsf1

Z-value: 1.77

Motif logo

logo of

Transcription factors associated with Hsf1

Gene Symbol Gene ID Gene Info
Hsf1
ENSMUSG00000022556.12 heat shock factor 1

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Hsf1mm39_v1_chr15_+_76361604_76361774-0.513.8e-01Click!

Activity profile of Hsf1 motif

Sorted Z-values of Hsf1 motif

Top targets:  

Promoter Log-likelihood Transcript Gene Gene Info
chr17_-_34218301 2.34 ENSMUST00000235463.2
H2-K1
histocompatibility 2, K1, K region
chr17_-_45883421 2.24 ENSMUST00000130406.2
Hsp90ab1
heat shock protein 90 alpha (cytosolic), class B member 1
chr12_-_110662256 2.04 ENSMUST00000149189.2
Hsp90aa1
heat shock protein 90, alpha (cytosolic), class A member 1
chr11_+_87684299 1.51 ENSMUST00000020779.11
Mpo
myeloperoxidase
chr4_-_136620376 1.37 ENSMUST00000046332.6
C1qc
complement component 1, q subcomponent, C chain
chr6_+_51447317 1.34 ENSMUST00000094623.10
Cbx3
chromobox 3
chr11_-_48836975 1.30 ENSMUST00000104958.2
Psme2b
protease (prosome, macropain) activator subunit 2B
chr12_-_110662677 1.21 ENSMUST00000124156.8
Hsp90aa1
heat shock protein 90, alpha (cytosolic), class A member 1
chr5_+_129864044 1.20 ENSMUST00000201414.5
Cct6a
chaperonin containing Tcp1, subunit 6a (zeta)
chr16_+_22926162 1.17 ENSMUST00000023599.13
ENSMUST00000168891.8
Eif4a2
eukaryotic translation initiation factor 4A2
chr6_-_128415640 1.16 ENSMUST00000032508.11
Fkbp4
FK506 binding protein 4
chr5_-_149559667 1.16 ENSMUST00000074846.14
Hsph1
heat shock 105kDa/110kDa protein 1
chr5_-_149559636 1.15 ENSMUST00000201452.4
Hsph1
heat shock 105kDa/110kDa protein 1
chr15_-_31601652 1.07 ENSMUST00000161266.2
Cct5
chaperonin containing Tcp1, subunit 5 (epsilon)
chr16_-_84632439 0.99 ENSMUST00000138279.2
Atp5j
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F
chr11_+_22940599 0.95 ENSMUST00000020562.5
Cct4
chaperonin containing Tcp1, subunit 4 (delta)
chr10_+_59159118 0.88 ENSMUST00000009789.15
ENSMUST00000092512.11
ENSMUST00000105466.3
P4ha1
procollagen-proline, 2-oxoglutarate 4-dioxygenase (proline 4-hydroxylase), alpha 1 polypeptide
chr15_-_31601932 0.85 ENSMUST00000022842.16
Cct5
chaperonin containing Tcp1, subunit 5 (epsilon)
chr12_+_75355082 0.81 ENSMUST00000118602.8
ENSMUST00000118966.8
ENSMUST00000055390.6
Rhoj
ras homolog family member J
chrX_-_72759748 0.79 ENSMUST00000002091.6
Bcap31
B cell receptor associated protein 31
chr7_-_46365108 0.70 ENSMUST00000006956.9
ENSMUST00000210913.2
Saa3
serum amyloid A 3
chr16_+_22926504 0.69 ENSMUST00000187168.7
ENSMUST00000232287.2
ENSMUST00000077605.12
Eif4a2
eukaryotic translation initiation factor 4A2
chr7_+_92210348 0.67 ENSMUST00000032842.13
ENSMUST00000085017.5
Ccdc90b
coiled-coil domain containing 90B
chr10_+_80662490 0.67 ENSMUST00000060987.15
ENSMUST00000177850.8
ENSMUST00000180036.8
ENSMUST00000179172.8
Oaz1
ornithine decarboxylase antizyme 1
chr11_+_22940519 0.62 ENSMUST00000173867.8
Cct4
chaperonin containing Tcp1, subunit 4 (delta)
chr16_-_87292592 0.61 ENSMUST00000176750.2
ENSMUST00000175977.8
Cct8
chaperonin containing Tcp1, subunit 8 (theta)
chr11_+_6510167 0.60 ENSMUST00000109722.9
Ccm2
cerebral cavernous malformation 2
chr5_-_149559792 0.60 ENSMUST00000202361.4
ENSMUST00000202089.4
ENSMUST00000200825.2
ENSMUST00000201559.4
Hsph1
heat shock 105kDa/110kDa protein 1
chr11_+_5048915 0.60 ENSMUST00000101610.10
Rhbdd3
rhomboid domain containing 3
chr4_+_148225139 0.56 ENSMUST00000140049.8
ENSMUST00000105707.2
Mad2l2
MAD2 mitotic arrest deficient-like 2
chr19_-_29790352 0.54 ENSMUST00000099525.5
Ranbp6
RAN binding protein 6
chr6_-_72416531 0.50 ENSMUST00000205335.2
ENSMUST00000206692.2
ENSMUST00000059472.10
Mat2a
methionine adenosyltransferase II, alpha
chr16_-_87292711 0.50 ENSMUST00000176041.8
ENSMUST00000026704.14
Cct8
chaperonin containing Tcp1, subunit 8 (theta)
chr17_+_25381414 0.49 ENSMUST00000073277.12
ENSMUST00000182621.8
Ccdc154
coiled-coil domain containing 154
chr15_+_31602252 0.48 ENSMUST00000042702.7
ENSMUST00000161061.3
Atpsckmt
ATP synthase C subunit lysine N-methyltransferase
chr12_+_117807607 0.48 ENSMUST00000176735.8
ENSMUST00000177339.2
Cdca7l
cell division cycle associated 7 like
chr11_-_23447866 0.48 ENSMUST00000128559.2
ENSMUST00000147157.8
ENSMUST00000109539.8
Ahsa2
AHA1, activator of heat shock protein ATPase 2
chr11_-_5492175 0.46 ENSMUST00000020776.5
Ccdc117
coiled-coil domain containing 117
chr7_+_49408847 0.45 ENSMUST00000085272.7
ENSMUST00000207895.2
Htatip2
HIV-1 Tat interactive protein 2
chr7_-_89590230 0.43 ENSMUST00000075010.12
Hikeshi
heat shock protein nuclear import factor
chr7_-_121666486 0.43 ENSMUST00000033159.4
Ears2
glutamyl-tRNA synthetase 2, mitochondrial
chr11_-_23448030 0.42 ENSMUST00000020529.13
Ahsa2
AHA1, activator of heat shock protein ATPase 2
chr1_+_91178288 0.41 ENSMUST00000171112.8
ENSMUST00000191533.2
Ube2f
ubiquitin-conjugating enzyme E2F (putative)
chr8_-_110419867 0.39 ENSMUST00000034164.6
Ist1
increased sodium tolerance 1 homolog (yeast)
chr12_-_110662723 0.38 ENSMUST00000021698.13
Hsp90aa1
heat shock protein 90, alpha (cytosolic), class A member 1
chrX_-_139857424 0.37 ENSMUST00000033805.15
ENSMUST00000112978.2
Psmd10
proteasome (prosome, macropain) 26S subunit, non-ATPase, 10
chr12_-_110662765 0.35 ENSMUST00000094361.11
Hsp90aa1
heat shock protein 90, alpha (cytosolic), class A member 1
chr16_-_84632383 0.34 ENSMUST00000114191.8
Atp5j
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F
chr7_-_19043955 0.34 ENSMUST00000207334.2
ENSMUST00000208505.2
ENSMUST00000207716.2
ENSMUST00000208326.2
ENSMUST00000003640.4
Fosb
FBJ osteosarcoma oncogene B
chr2_+_163535925 0.33 ENSMUST00000109400.3
Pkig
protein kinase inhibitor, gamma
chr6_-_51446850 0.33 ENSMUST00000069949.13
Hnrnpa2b1
heterogeneous nuclear ribonucleoprotein A2/B1
chr9_+_40712562 0.32 ENSMUST00000117557.8
Hspa8
heat shock protein 8
chr9_+_18203421 0.32 ENSMUST00000001825.9
Chordc1
cysteine and histidine-rich domain (CHORD)-containing, zinc-binding protein 1
chr17_-_35265702 0.32 ENSMUST00000097338.11
Msh5
mutS homolog 5
chr3_+_79498663 0.31 ENSMUST00000029382.13
Ppid
peptidylprolyl isomerase D (cyclophilin D)
chr6_+_29853745 0.31 ENSMUST00000064872.13
ENSMUST00000152581.8
ENSMUST00000176265.8
ENSMUST00000154079.8
Ahcyl2
S-adenosylhomocysteine hydrolase-like 2
chr4_+_40722911 0.31 ENSMUST00000164233.8
ENSMUST00000137246.8
ENSMUST00000125442.8
Dnaja1
DnaJ heat shock protein family (Hsp40) member A1
chr1_-_55127183 0.30 ENSMUST00000027123.15
Hspd1
heat shock protein 1 (chaperonin)
chr17_+_31783708 0.30 ENSMUST00000097352.11
ENSMUST00000237248.2
ENSMUST00000235869.2
ENSMUST00000175806.9
Pknox1
Pbx/knotted 1 homeobox
chr12_-_104964936 0.29 ENSMUST00000109927.2
ENSMUST00000095439.11
Syne3
spectrin repeat containing, nuclear envelope family member 3
chr2_+_120294046 0.29 ENSMUST00000028749.15
ENSMUST00000110721.9
ENSMUST00000239364.2
Capn3
calpain 3
chr19_-_7017295 0.28 ENSMUST00000025918.9
Stip1
stress-induced phosphoprotein 1
chr10_-_86541349 0.28 ENSMUST00000020238.14
Hsp90b1
heat shock protein 90, beta (Grp94), member 1
chr5_-_149559737 0.28 ENSMUST00000200805.4
Hsph1
heat shock 105kDa/110kDa protein 1
chr5_+_149121458 0.27 ENSMUST00000122160.8
ENSMUST00000100410.10
ENSMUST00000119685.8
Uspl1
ubiquitin specific peptidase like 1
chr6_+_58808733 0.27 ENSMUST00000126292.8
ENSMUST00000031823.12
Herc3
hect domain and RLD 3
chr7_+_136496328 0.26 ENSMUST00000081510.4
Mgmt
O-6-methylguanine-DNA methyltransferase
chr14_+_66205932 0.26 ENSMUST00000022616.14
Clu
clusterin
chr6_-_51446752 0.26 ENSMUST00000204188.3
ENSMUST00000203220.3
ENSMUST00000114459.8
ENSMUST00000090002.10
Hnrnpa2b1
heterogeneous nuclear ribonucleoprotein A2/B1
chr4_-_133273243 0.25 ENSMUST00000030665.7
Nudc
nudC nuclear distribution protein
chr5_+_149121355 0.25 ENSMUST00000050472.16
Uspl1
ubiquitin specific peptidase like 1
chr14_-_66071412 0.25 ENSMUST00000022613.10
Esco2
establishment of sister chromatid cohesion N-acetyltransferase 2
chr9_-_105372235 0.24 ENSMUST00000176190.8
ENSMUST00000163879.9
ENSMUST00000112558.10
ENSMUST00000176363.9
Atp2c1
ATPase, Ca++-sequestering
chr1_-_55127312 0.24 ENSMUST00000127861.8
ENSMUST00000144077.3
Hspd1
heat shock protein 1 (chaperonin)
chr1_+_179788675 0.23 ENSMUST00000076687.12
ENSMUST00000097450.10
ENSMUST00000212756.2
Cdc42bpa
CDC42 binding protein kinase alpha
chr15_-_100301124 0.23 ENSMUST00000124324.2
Slc11a2
solute carrier family 11 (proton-coupled divalent metal ion transporters), member 2
chr2_+_72128239 0.23 ENSMUST00000144111.2
Map3k20
mitogen-activated protein kinase kinase kinase 20
chr5_+_149121488 0.23 ENSMUST00000139474.8
ENSMUST00000117878.8
Uspl1
ubiquitin specific peptidase like 1
chr5_-_129864202 0.21 ENSMUST00000136507.4
Psph
phosphoserine phosphatase
chr16_-_84632513 0.19 ENSMUST00000023608.14
Atp5j
ATP synthase, H+ transporting, mitochondrial F0 complex, subunit F
chr11_+_70591299 0.19 ENSMUST00000152618.9
ENSMUST00000102554.8
ENSMUST00000094499.11
ENSMUST00000072187.12
ENSMUST00000137119.3
Kif1c
kinesin family member 1C
chr15_-_81283795 0.18 ENSMUST00000023039.15
St13
suppression of tumorigenicity 13
chr12_-_104718159 0.18 ENSMUST00000041987.7
Dicer1
dicer 1, ribonuclease type III
chr8_+_27513819 0.17 ENSMUST00000033873.9
ENSMUST00000211043.2
Erlin2
ER lipid raft associated 2
chr7_+_110628158 0.17 ENSMUST00000005749.6
Ctr9
CTR9 homolog, Paf1/RNA polymerase II complex component
chr8_+_88999031 0.17 ENSMUST00000169037.9
Adcy7
adenylate cyclase 7
chr1_-_160040286 0.15 ENSMUST00000195654.2
ENSMUST00000014370.11
Cacybp
calcyclin binding protein
chr8_+_84335176 0.15 ENSMUST00000212300.2
Dnajb1
DnaJ heat shock protein family (Hsp40) member B1
chr19_-_34143437 0.14 ENSMUST00000025686.9
Ankrd22
ankyrin repeat domain 22
chr5_-_36853281 0.14 ENSMUST00000031091.13
ENSMUST00000140653.2
D5Ertd579e
DNA segment, Chr 5, ERATO Doi 579, expressed
chr6_+_68098030 0.14 ENSMUST00000103317.3
Igkv1-117
immunoglobulin kappa variable 1-117
chr10_-_61219229 0.13 ENSMUST00000020289.10
Pald1
phosphatase domain containing, paladin 1
chr7_-_99002204 0.11 ENSMUST00000208292.2
ENSMUST00000207989.2
ENSMUST00000208749.2
ENSMUST00000169437.9
ENSMUST00000208119.2
ENSMUST00000207849.2
Serpinh1
serine (or cysteine) peptidase inhibitor, clade H, member 1
chr5_+_29940686 0.11 ENSMUST00000008733.15
Dnajb6
DnaJ heat shock protein family (Hsp40) member B6
chr9_-_103357564 0.11 ENSMUST00000124310.5
Bfsp2
beaded filament structural protein 2, phakinin
chr16_-_22084700 0.08 ENSMUST00000161286.8
Tra2b
transformer 2 beta
chr7_-_19043525 0.07 ENSMUST00000208446.2
Fosb
FBJ osteosarcoma oncogene B
chr5_+_135916847 0.07 ENSMUST00000111155.2
Hspb1
heat shock protein 1
chr5_+_135916764 0.07 ENSMUST00000005077.7
Hspb1
heat shock protein 1
chr2_+_29014106 0.07 ENSMUST00000129544.8
Setx
senataxin
chrX_+_41238193 0.06 ENSMUST00000115073.9
ENSMUST00000115072.8
Stag2
stromal antigen 2
chr15_+_28203872 0.06 ENSMUST00000067048.8
Dnah5
dynein, axonemal, heavy chain 5
chr3_+_85947806 0.06 ENSMUST00000238222.2
Sh3d19
SH3 domain protein D19
chr9_-_105372330 0.06 ENSMUST00000038118.15
Atp2c1
ATPase, Ca++-sequestering
chr3_+_85948030 0.05 ENSMUST00000238545.2
Sh3d19
SH3 domain protein D19
chr15_+_81284333 0.05 ENSMUST00000163754.9
ENSMUST00000041609.11
Xpnpep3
X-prolyl aminopeptidase 3, mitochondrial
chr7_-_89590404 0.04 ENSMUST00000153470.9
Hikeshi
heat shock protein nuclear import factor
chr11_+_83328503 0.03 ENSMUST00000037378.6
1700020L24Rik
RIKEN cDNA 1700020L24 gene
chr12_+_24881582 0.03 ENSMUST00000221952.2
ENSMUST00000078902.8
ENSMUST00000110942.11
Mboat2
membrane bound O-acyltransferase domain containing 2
chr5_-_86616849 0.03 ENSMUST00000101073.3
Tmprss11a
transmembrane protease, serine 11a
chr9_+_50664288 0.02 ENSMUST00000214962.2
ENSMUST00000216755.2
Cryab
crystallin, alpha B
chr4_+_13784749 0.02 ENSMUST00000098256.4
Runx1t1
RUNX1 translocation partner 1
chr5_+_92479687 0.02 ENSMUST00000125462.8
ENSMUST00000113083.9
ENSMUST00000121096.8
Art3
ADP-ribosyltransferase 3
chr2_+_157401998 0.01 ENSMUST00000153739.9
ENSMUST00000173595.2
ENSMUST00000109526.2
ENSMUST00000173839.2
ENSMUST00000173041.8
ENSMUST00000173793.8
ENSMUST00000172487.2
ENSMUST00000088484.6
Nnat
neuronatin
chr6_+_67993691 0.01 ENSMUST00000103314.3
Igkv1-122
immunoglobulin kappa chain variable 1-122
chr9_+_50664207 0.01 ENSMUST00000034562.9
Cryab
crystallin, alpha B
chr8_+_36956345 0.01 ENSMUST00000171777.2
Trmt9b
tRNA methyltransferase 9B
chr17_+_15261470 0.01 ENSMUST00000097393.11
Ermard
ER membrane associated RNA degradation
chr6_+_68247469 0.01 ENSMUST00000103321.3
Igkv1-110
immunoglobulin kappa variable 1-110
chr16_-_88548523 0.01 ENSMUST00000053149.4
Krtap13
keratin associated protein 13
chr13_-_12479804 0.01 ENSMUST00000124888.8
Lgals8
lectin, galactose binding, soluble 8
chrX_-_76968668 0.01 ENSMUST00000063127.4
5430402E10Rik
RIKEN cDNA 5430402E10 gene
chr14_+_50690511 0.01 ENSMUST00000089838.2
Olfr740
olfactory receptor 740
chr17_-_50401305 0.01 ENSMUST00000113195.8
Rftn1
raftlin lipid raft linker 1
chrX_-_149440388 0.01 ENSMUST00000151403.9
ENSMUST00000087253.11
ENSMUST00000112709.8
ENSMUST00000163969.8
ENSMUST00000087258.10
Tro
trophinin
chr3_+_117368876 0.01 ENSMUST00000106473.5
Plppr5
phospholipid phosphatase related 5
chr9_+_102382949 0.01 ENSMUST00000039390.6
Ky
kyphoscoliosis peptidase
chr18_-_36899245 0.00 ENSMUST00000061522.8
Dnd1
DND microRNA-mediated repression inhibitor 1
chr12_+_87993774 0.00 ENSMUST00000178852.2
Eif1ad11
eukaryotic translation initiation factor 1A domain containing 11
chr1_+_66360865 0.00 ENSMUST00000114013.8
Map2
microtubule-associated protein 2
chrX_-_149440362 0.00 ENSMUST00000148604.2
Tro
trophinin
chr18_+_37637317 0.00 ENSMUST00000052179.8
Pcdhb20
protocadherin beta 20
chr8_-_49009043 0.00 ENSMUST00000110343.3
Tenm3
teneurin transmembrane protein 3
chr14_+_50770871 0.00 ENSMUST00000071294.3
Olfr743
olfactory receptor 743

Network of associatons between targets according to the STRING database.

First level regulatory network of Hsf1

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.
View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 2.2 GO:1903660 transforming growth factor beta activation(GO:0036363) regulation of complement-dependent cytotoxicity(GO:1903659) negative regulation of complement-dependent cytotoxicity(GO:1903660)
0.6 4.0 GO:0045583 regulation of cytotoxic T cell differentiation(GO:0045583) positive regulation of cytotoxic T cell differentiation(GO:0045585)
0.5 1.5 GO:0002149 hypochlorous acid metabolic process(GO:0002148) hypochlorous acid biosynthetic process(GO:0002149)
0.5 2.3 GO:0002484 antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway(GO:0002484) antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent(GO:0002485)
0.4 5.8 GO:1904871 protein localization to nuclear body(GO:1903405) protein localization to Cajal body(GO:1904867) regulation of protein localization to Cajal body(GO:1904869) positive regulation of protein localization to Cajal body(GO:1904871)
0.3 3.2 GO:1903753 negative regulation of p38MAPK cascade(GO:1903753)
0.3 0.8 GO:0070973 protein localization to endoplasmic reticulum exit site(GO:0070973) positive regulation of retrograde protein transport, ER to cytosol(GO:1904154)
0.2 0.6 GO:1990428 miRNA transport(GO:1990428)
0.2 0.5 GO:0045041 protein import into mitochondrial intermembrane space(GO:0045041)
0.2 0.7 GO:1902268 negative regulation of polyamine transmembrane transport(GO:1902268)
0.2 1.4 GO:0045650 negative regulation of macrophage differentiation(GO:0045650)
0.2 0.5 GO:0046021 regulation of transcription from RNA polymerase II promoter, mitotic(GO:0046021) positive regulation of transcription from RNA polymerase II promoter during mitosis(GO:0046022)
0.1 0.7 GO:0030576 Cajal body organization(GO:0030576)
0.1 0.4 GO:0070682 proteasome regulatory particle assembly(GO:0070682)
0.1 0.6 GO:2000048 negative regulation of cell-cell adhesion mediated by cadherin(GO:2000048)
0.1 0.3 GO:0097212 protein targeting to vacuole involved in autophagy(GO:0071211) lysosomal membrane organization(GO:0097212) positive regulation of protein folding(GO:1903334)
0.1 0.9 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.1 0.4 GO:0009838 abscission(GO:0009838)
0.1 0.5 GO:0006556 S-adenosylmethionine biosynthetic process(GO:0006556)
0.1 0.3 GO:0030026 cellular manganese ion homeostasis(GO:0030026) Golgi calcium ion homeostasis(GO:0032468) manganese ion homeostasis(GO:0055071)
0.1 0.3 GO:1990091 sodium-dependent self proteolysis(GO:1990091)
0.1 0.4 GO:0070127 tRNA aminoacylation for mitochondrial protein translation(GO:0070127)
0.1 0.2 GO:2001160 regulation of histone H3-K79 methylation(GO:2001160)
0.1 0.3 GO:0071492 cellular response to UV-A(GO:0071492)
0.1 0.8 GO:0061299 retina vasculature morphogenesis in camera-type eye(GO:0061299)
0.0 0.5 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 1.2 GO:0031115 negative regulation of microtubule polymerization(GO:0031115)
0.0 1.5 GO:0015985 energy coupled proton transport, down electrochemical gradient(GO:0015985) ATP synthesis coupled proton transport(GO:0015986)
0.0 0.3 GO:1902998 regulation of neuronal signal transduction(GO:1902847) positive regulation of neurofibrillary tangle assembly(GO:1902998)
0.0 0.6 GO:0032815 negative regulation of natural killer cell activation(GO:0032815)
0.0 0.6 GO:0060837 blood vessel endothelial cell differentiation(GO:0060837)
0.0 0.2 GO:0015676 vanadium ion transport(GO:0015676) lead ion transport(GO:0015692)
0.0 0.2 GO:0070173 regulation of enamel mineralization(GO:0070173)
0.0 0.3 GO:0033353 S-adenosylmethionine cycle(GO:0033353)
0.0 1.9 GO:0010501 RNA secondary structure unwinding(GO:0010501)
0.0 0.3 GO:0006307 DNA dealkylation involved in DNA repair(GO:0006307)
0.0 0.7 GO:0007252 I-kappaB phosphorylation(GO:0007252)
0.0 0.2 GO:0006564 L-serine biosynthetic process(GO:0006564)
0.0 0.2 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.0 0.1 GO:0038033 positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway(GO:0038033)
0.0 0.1 GO:0031554 regulation of DNA-templated transcription, termination(GO:0031554)
0.0 0.5 GO:0007097 nuclear migration(GO:0007097) establishment of nucleus localization(GO:0040023)
0.0 0.3 GO:0071318 cellular response to ATP(GO:0071318)
0.0 0.3 GO:0090286 cytoskeletal anchoring at nuclear membrane(GO:0090286)
0.0 0.2 GO:0045541 negative regulation of cholesterol biosynthetic process(GO:0045541) negative regulation of cholesterol metabolic process(GO:0090206)
0.0 0.3 GO:2000480 negative regulation of cAMP-dependent protein kinase activity(GO:2000480)
0.0 0.3 GO:0051026 chiasma assembly(GO:0051026)
0.0 0.4 GO:0045116 protein neddylation(GO:0045116)
0.0 0.1 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 0.2 GO:0071361 cellular response to ethanol(GO:0071361)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 4.0 GO:0097226 sperm mitochondrial sheath(GO:0097226)
0.4 2.2 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.3 5.8 GO:0005832 chaperonin-containing T-complex(GO:0005832)
0.2 0.9 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.2 1.3 GO:0035985 senescence-associated heterochromatin focus(GO:0035985)
0.2 2.3 GO:0042612 MHC class I protein complex(GO:0042612)
0.2 0.5 GO:0048269 methionine adenosyltransferase complex(GO:0048269)
0.1 0.6 GO:0016035 zeta DNA polymerase complex(GO:0016035)
0.1 0.8 GO:0005784 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.1 1.5 GO:0000276 mitochondrial proton-transporting ATP synthase complex, coupling factor F(o)(GO:0000276)
0.1 1.5 GO:0042582 primary lysosome(GO:0005766) azurophil granule(GO:0042582)
0.1 0.5 GO:0046696 lipopolysaccharide receptor complex(GO:0046696)
0.1 0.5 GO:0099524 region of cytosol(GO:0099522) postsynaptic cytosol(GO:0099524)
0.0 0.6 GO:0071598 neuronal ribonucleoprotein granule(GO:0071598)
0.0 0.2 GO:0070826 paraferritin complex(GO:0070826)
0.0 0.4 GO:0008540 proteasome regulatory particle, base subcomplex(GO:0008540)
0.0 1.0 GO:0034364 high-density lipoprotein particle(GO:0034364)
0.0 0.3 GO:0034993 microtubule organizing center attachment site(GO:0034992) LINC complex(GO:0034993)
0.0 0.3 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.4 GO:0090543 Flemming body(GO:0090543)
0.0 0.2 GO:0016593 Cdc73/Paf1 complex(GO:0016593)
0.0 1.2 GO:0044295 axonal growth cone(GO:0044295)
0.0 0.2 GO:0070578 micro-ribonucleoprotein complex(GO:0035068) RISC-loading complex(GO:0070578)
0.0 0.7 GO:0015030 Cajal body(GO:0015030)
0.0 1.4 GO:0005581 collagen trimer(GO:0005581)
0.0 0.2 GO:0030877 beta-catenin destruction complex(GO:0030877)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.9 6.2 GO:0002135 CTP binding(GO:0002135)
0.3 3.2 GO:0000774 adenyl-nucleotide exchange factor activity(GO:0000774)
0.2 0.7 GO:0070122 isopeptidase activity(GO:0070122) ubiquitin-like protein-specific isopeptidase activity(GO:0070138) SUMO-specific isopeptidase activity(GO:0070140)
0.2 1.2 GO:0071987 WD40-repeat domain binding(GO:0071987)
0.2 1.2 GO:0032767 copper-dependent protein binding(GO:0032767)
0.2 0.7 GO:0008073 ornithine decarboxylase inhibitor activity(GO:0008073)
0.1 0.9 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656)
0.1 2.3 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.1 0.5 GO:0004478 methionine adenosyltransferase activity(GO:0004478)
0.1 4.8 GO:0044183 protein binding involved in protein folding(GO:0044183)
0.1 0.7 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.1 1.3 GO:1990226 histone methyltransferase binding(GO:1990226)
0.1 0.3 GO:0031686 A1 adenosine receptor binding(GO:0031686)
0.1 0.3 GO:0015410 manganese-transporting ATPase activity(GO:0015410)
0.1 0.6 GO:1990247 N6-methyladenosine-containing RNA binding(GO:1990247)
0.0 0.3 GO:0016018 cyclosporin A binding(GO:0016018)
0.0 0.3 GO:0004013 adenosylhomocysteinase activity(GO:0004013) trialkylsulfonium hydrolase activity(GO:0016802)
0.0 0.2 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086) lead ion transmembrane transporter activity(GO:0015094) vanadium ion transmembrane transporter activity(GO:0015100) ferrous iron uptake transmembrane transporter activity(GO:0015639)
0.0 0.8 GO:0042288 MHC class I protein binding(GO:0042288)
0.0 0.3 GO:0008172 S-methyltransferase activity(GO:0008172)
0.0 0.4 GO:0019788 NEDD8 transferase activity(GO:0019788)
0.0 0.2 GO:0032296 ribonuclease III activity(GO:0004525) double-stranded RNA-specific ribonuclease activity(GO:0032296)
0.0 0.2 GO:0004647 phosphoserine phosphatase activity(GO:0004647)
0.0 0.2 GO:0055131 C3HC4-type RING finger domain binding(GO:0055131)
0.0 1.9 GO:0003743 translation initiation factor activity(GO:0003743)
0.0 1.0 GO:0001671 ATPase activator activity(GO:0001671)
0.0 0.1 GO:0001160 transcription termination site sequence-specific DNA binding(GO:0001147) transcription termination site DNA binding(GO:0001160)
0.0 0.3 GO:0046790 virion binding(GO:0046790)
0.0 1.5 GO:0004601 peroxidase activity(GO:0004601)
0.0 0.6 GO:0008432 JUN kinase binding(GO:0008432)
0.0 0.3 GO:0030983 mismatched DNA binding(GO:0030983)
0.0 0.3 GO:0031432 titin binding(GO:0031432)
0.0 0.3 GO:0004862 cAMP-dependent protein kinase inhibitor activity(GO:0004862)
0.0 0.5 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 1.5 GO:0015078 hydrogen ion transmembrane transporter activity(GO:0015078)
0.0 0.2 GO:0004016 adenylate cyclase activity(GO:0004016)
0.0 0.3 GO:0051787 misfolded protein binding(GO:0051787)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 4.0 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 1.5 PID IL23 PATHWAY IL23-mediated signaling events
0.0 1.5 PID HNF3A PATHWAY FOXA1 transcription factor network
0.0 0.6 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 2.2 PID VEGFR1 2 PATHWAY Signaling events mediated by VEGFR1 and VEGFR2
0.0 0.7 PID AURORA A PATHWAY Aurora A signaling
0.0 1.2 PID REG GR PATHWAY Glucocorticoid receptor regulatory network

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 6.2 REACTOME SEMA3A PAK DEPENDENT AXON REPULSION Genes involved in Sema3A PAK dependent Axon repulsion
0.2 5.8 REACTOME FORMATION OF TUBULIN FOLDING INTERMEDIATES BY CCT TRIC Genes involved in Formation of tubulin folding intermediates by CCT/TriC
0.2 1.4 REACTOME CREATION OF C4 AND C2 ACTIVATORS Genes involved in Creation of C4 and C2 activators
0.1 1.5 REACTOME FORMATION OF ATP BY CHEMIOSMOTIC COUPLING Genes involved in Formation of ATP by chemiosmotic coupling
0.1 1.9 REACTOME DEADENYLATION OF MRNA Genes involved in Deadenylation of mRNA
0.1 0.5 REACTOME DESTABILIZATION OF MRNA BY AUF1 HNRNP D0 Genes involved in Destabilization of mRNA by AUF1 (hnRNP D0)
0.0 0.3 REACTOME ACTIVATION OF CHAPERONE GENES BY ATF6 ALPHA Genes involved in Activation of Chaperone Genes by ATF6-alpha
0.0 1.3 REACTOME RNA POL I TRANSCRIPTION Genes involved in RNA Polymerase I Transcription
0.0 0.4 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 1.0 REACTOME REGULATION OF ORNITHINE DECARBOXYLASE ODC Genes involved in Regulation of ornithine decarboxylase (ODC)
0.0 0.5 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 0.5 REACTOME MITOCHONDRIAL PROTEIN IMPORT Genes involved in Mitochondrial Protein Import