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avrg: GFI1 WT vs 36n/n vs KD

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Results for Hsfy2

Z-value: 3.08

Motif logo

Transcription factors associated with Hsfy2

Gene Symbol Gene ID Gene Info
ENSMUSG00000045336.6 heat shock transcription factor, Y-linked 2

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Hsfy2mm39_v1_chr1_-_56676589_56676606-0.721.7e-01Click!

Activity profile of Hsfy2 motif

Sorted Z-values of Hsfy2 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr15_-_79967543 3.94 ENSMUST00000081650.15
ribosomal protein L3
chr6_+_52691204 3.53 ENSMUST00000138040.8
ENSMUST00000129660.2
Tax1 (human T cell leukemia virus type I) binding protein 1
chr11_+_32155483 2.03 ENSMUST00000121182.2
small nuclear ribonucleoprotein 25 (U11/U12)
chr1_-_93729562 1.84 ENSMUST00000112890.3
deoxythymidylate kinase
chr6_+_40619913 1.81 ENSMUST00000238599.2
maltase-glucoamylase
chr3_-_94794256 1.80 ENSMUST00000005923.7
proteasome (prosome, macropain) subunit, beta type 4
chr6_+_116528102 1.72 ENSMUST00000122096.3
eukaryotic translation initiation factor 4A3 like 2
chr5_+_21577640 1.63 ENSMUST00000035799.6
fibrinogen-like protein 2
chr11_+_32155415 1.54 ENSMUST00000039601.10
ENSMUST00000149043.3
small nuclear ribonucleoprotein 25 (U11/U12)
chr10_-_79710044 1.53 ENSMUST00000167897.8
phospholipid phosphatase related 3
chr8_-_95564881 1.41 ENSMUST00000034233.15
ENSMUST00000162538.9
cytokine induced apoptosis inhibitor 1
chr9_-_57552392 1.39 ENSMUST00000216934.2
c-src tyrosine kinase
chr18_+_66591604 1.36 ENSMUST00000025399.9
ENSMUST00000237161.2
ENSMUST00000236933.2
phorbol-12-myristate-13-acetate-induced protein 1
chr7_-_78432774 1.24 ENSMUST00000032841.7
mitochondrial ribosomal protein L46
chr10_-_112764879 1.20 ENSMUST00000099276.4
ataxin 7-like 3B
chr17_-_26015937 1.17 ENSMUST00000235925.2
ENSMUST00000238040.2
meteorin, glial cell differentiation regulator
chr19_+_46329552 1.16 ENSMUST00000128041.8
major facilitator superfamily domain containing 13a
chr13_-_30729242 1.13 ENSMUST00000042834.4
ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1
chr14_-_65830463 1.09 ENSMUST00000225355.2
ENSMUST00000022609.7
elongator acetyltransferase complex subunit 3
chr11_-_75313350 1.09 ENSMUST00000125982.2
ENSMUST00000137103.8
serine (or cysteine) peptidase inhibitor, clade F, member 1
chr11_-_120463667 1.08 ENSMUST00000168360.2
prolyl 4-hydroxylase, beta polypeptide
chr9_-_55419442 1.06 ENSMUST00000034866.9
electron transferring flavoprotein, alpha polypeptide
chr1_-_134289670 1.04 ENSMUST00000049470.11
transmembrane protein 183A
chr9_-_64080161 0.99 ENSMUST00000176299.8
ENSMUST00000130127.8
ENSMUST00000176794.8
ENSMUST00000177045.8
zwilch kinetochore protein
chr3_-_20296337 0.99 ENSMUST00000001921.3
carboxypeptidase A3, mast cell
chr1_-_78465479 0.99 ENSMUST00000190441.2
ENSMUST00000170217.8
ENSMUST00000188247.7
ENSMUST00000068333.14
phenylalanyl-tRNA synthetase, beta subunit
chr17_-_36369263 0.99 ENSMUST00000113742.3
predicted gene 11127
chr2_-_101479846 0.98 ENSMUST00000078494.6
ENSMUST00000160722.8
ENSMUST00000160037.8
recombination activating 1
intraflagellar transport associated protein
chr9_+_64080644 0.97 ENSMUST00000034966.9
ribosomal protein L4
chr7_+_78432867 0.97 ENSMUST00000032840.5
mitochondrial ribosomal protein S11
chr10_-_79710067 0.96 ENSMUST00000166023.2
ENSMUST00000167707.2
ENSMUST00000165601.8
phospholipid phosphatase related 3
chr9_+_21634779 0.95 ENSMUST00000034713.9
low density lipoprotein receptor
chrX_-_8059597 0.94 ENSMUST00000143223.2
ENSMUST00000033509.15
phenylalkylamine Ca2+ antagonist (emopamil) binding protein
chr17_-_31731222 0.93 ENSMUST00000236665.2
WD repeat domain 4
chr10_+_52293617 0.92 ENSMUST00000023830.16
NUS1 dehydrodolichyl diphosphate synthase subunit
chr17_+_28910302 0.89 ENSMUST00000004990.14
ENSMUST00000114754.8
ENSMUST00000062694.16
mitogen-activated protein kinase 14
chr7_-_26866157 0.87 ENSMUST00000080058.11
egl-9 family hypoxia-inducible factor 2
chr10_-_7539009 0.85 ENSMUST00000163085.8
ENSMUST00000159917.8
protein-L-isoaspartate (D-aspartate) O-methyltransferase 1
chr13_+_51799268 0.84 ENSMUST00000075853.6
CDC28 protein kinase regulatory subunit 2
chr9_-_111086528 0.84 ENSMUST00000199404.2
mutL homolog 1
chr2_-_29938841 0.83 ENSMUST00000113711.3
dynein 2 intermediate chain 2
chr3_+_142406827 0.82 ENSMUST00000044392.11
ENSMUST00000199519.5
kynurenine aminotransferase 3
chr5_+_32616566 0.82 ENSMUST00000202078.2
protein phosphatase 1 catalytic subunit beta
chr6_+_123206802 0.79 ENSMUST00000112554.9
ENSMUST00000024118.11
ENSMUST00000117130.8
C-type lectin domain family 4, member n
chr7_+_3706992 0.78 ENSMUST00000006496.15
ENSMUST00000108623.8
ENSMUST00000139818.2
ENSMUST00000108625.8
ribosomal protein S9
chr14_+_61022006 0.77 ENSMUST00000063562.9
ENSMUST00000225043.2
mitochondrial intermediate peptidase
chr14_+_8348779 0.77 ENSMUST00000022256.5
proteasome (prosome, macropain) 26S subunit, non-ATPase, 6
chr11_-_69553390 0.76 ENSMUST00000129224.8
ENSMUST00000155200.8
mannose-P-dolichol utilization defect 1
chr11_-_120464062 0.74 ENSMUST00000026122.11
prolyl 4-hydroxylase, beta polypeptide
chr2_-_32872019 0.73 ENSMUST00000153484.7
solute carrier family 2, (facilitated glucose transporter), member 8
chr11_-_117764258 0.73 ENSMUST00000033230.8
threonine aldolase 1
chr3_+_142406787 0.72 ENSMUST00000106218.8
kynurenine aminotransferase 3
chr17_-_46985181 0.71 ENSMUST00000024766.7
ribosomal RNA processing 36
chr11_+_80701001 0.71 ENSMUST00000040865.9
transmembrane protein 98
chr4_+_98284128 0.68 ENSMUST00000107030.9
PATJ, crumbs cell polarity complex component
chr11_-_72106418 0.66 ENSMUST00000021157.9
mediator complex subunit 31
chr12_-_102709884 0.65 ENSMUST00000173760.9
ENSMUST00000178384.2
modulator of apoptosis 1
chr14_-_55880980 0.65 ENSMUST00000132338.8
transmembrane 9 superfamily member 1
chr17_+_26471870 0.65 ENSMUST00000025023.15
Luc7-like
chr1_-_93729650 0.65 ENSMUST00000027503.14
deoxythymidylate kinase
chr3_+_122717852 0.64 ENSMUST00000106429.6
RIKEN cDNA 1810037I17 gene
chr18_+_84869883 0.64 ENSMUST00000163083.2
cytochrome b5 type A (microsomal)
chrX_+_7750558 0.64 ENSMUST00000208640.2
ENSMUST00000207114.2
ENSMUST00000208633.2
ENSMUST00000208397.2
ENSMUST00000153620.3
ENSMUST00000123277.8
solute carrier family 35 (UDP-galactose transporter), member A2
chr2_-_90735171 0.64 ENSMUST00000005647.4
NADH:ubiquinone oxidoreductase core subunit S3
chr2_-_32872032 0.63 ENSMUST00000195863.2
ENSMUST00000028129.13
solute carrier family 2, (facilitated glucose transporter), member 8
chr19_-_38212544 0.63 ENSMUST00000067167.6
FRA10AC1 homolog (human)
chr19_-_4175837 0.63 ENSMUST00000121402.2
ENSMUST00000117831.8
aryl-hydrocarbon receptor-interacting protein
chr15_+_90108480 0.63 ENSMUST00000100309.3
ENSMUST00000231200.2
asparagine-linked glycosylation 10B (alpha-1,2-glucosyltransferase)
chr9_-_107971640 0.63 ENSMUST00000081309.13
ENSMUST00000191985.2
acylpeptide hydrolase
chr11_-_102771751 0.62 ENSMUST00000021306.14
elongation factor Tu GTP binding domain containing 2
chr7_-_118304930 0.62 ENSMUST00000207323.2
ENSMUST00000038791.15
glycerophosphodiester phosphodiesterase 1
chr8_+_53964721 0.61 ENSMUST00000211424.2
ENSMUST00000033920.6
aspartylglucosaminidase
chr13_-_63036096 0.60 ENSMUST00000092888.11
fructose bisphosphatase 1
chr2_+_101716577 0.60 ENSMUST00000028584.8
COMM domain containing 9
chr5_+_145104011 0.60 ENSMUST00000160629.8
ENSMUST00000070487.12
ENSMUST00000160422.8
ENSMUST00000162244.8
cleavage and polyadenylation specific factor 4
chr10_-_75670217 0.59 ENSMUST00000218500.2
glutathione S-transferase, theta 2
chr17_+_26471889 0.58 ENSMUST00000114976.9
ENSMUST00000140427.8
ENSMUST00000119928.8
Luc7-like
chr14_-_31299275 0.57 ENSMUST00000112027.9
collagen-like tail subunit (single strand of homotrimer) of asymmetric acetylcholinesterase
chr6_-_5256225 0.57 ENSMUST00000125686.8
paraoxonase 3
chr9_-_103079312 0.56 ENSMUST00000035157.10
signal recognition particle receptor, B subunit
chr11_-_102771806 0.56 ENSMUST00000107060.8
elongation factor Tu GTP binding domain containing 2
chr7_-_64041996 0.56 ENSMUST00000032735.8
M-phase phosphoprotein 10 (U3 small nucleolar ribonucleoprotein)
chr14_+_54924439 0.55 ENSMUST00000227269.2
RIKEN cDNA 1700123O20 gene
chr7_+_141041637 0.55 ENSMUST00000167491.8
ENSMUST00000165194.2
calcium release activated channel regulator 2B
chr6_-_5256282 0.55 ENSMUST00000031773.9
paraoxonase 3
chr11_-_69553451 0.55 ENSMUST00000018905.12
mannose-P-dolichol utilization defect 1
chr9_+_95739650 0.54 ENSMUST00000034980.9
ataxia telangiectasia and Rad3 related
chr11_+_49327451 0.54 ENSMUST00000215226.2
olfactory receptor 1388
chr15_+_8138805 0.54 ENSMUST00000230017.2
nucleoporin 155
chr13_-_99481160 0.54 ENSMUST00000022153.8
pentatricopeptide repeat domain 2
chr9_+_66853343 0.53 ENSMUST00000040917.14
ENSMUST00000127896.8
ribosomal protein S27-like
chr14_-_55881177 0.53 ENSMUST00000138085.2
transmembrane 9 superfamily member 1
chr8_+_95564949 0.53 ENSMUST00000034234.15
ENSMUST00000159871.4
coenzyme Q9
chr9_-_64160899 0.52 ENSMUST00000005066.9
mitogen-activated protein kinase kinase 1
chr11_+_60619224 0.52 ENSMUST00000018743.5
mitochondrial elongation factor 2
chr6_-_124718316 0.52 ENSMUST00000004389.6
gene rich cluster, C10 gene
chr11_+_40624466 0.51 ENSMUST00000020578.11
NudC domain containing 2
chr9_-_106124917 0.51 ENSMUST00000112524.9
ENSMUST00000219129.2
aminolevulinic acid synthase 1
chr2_-_38534099 0.51 ENSMUST00000028083.6
proteasome (prosome, macropain) subunit, beta type 7
chr7_-_26865838 0.50 ENSMUST00000108382.2
egl-9 family hypoxia-inducible factor 2
chr6_-_122778598 0.50 ENSMUST00000165884.8
solute carrier family 2 (facilitated glucose transporter), member 3
chr15_-_97618982 0.50 ENSMUST00000023105.5
endonuclease, polyU-specific
chrX_-_95000496 0.50 ENSMUST00000079987.13
ENSMUST00000113864.3
LAS1-like (S. cerevisiae)
chr16_+_35758836 0.49 ENSMUST00000114878.8
poly (ADP-ribose) polymerase family, member 9
chrX_+_7750483 0.49 ENSMUST00000115663.10
ENSMUST00000096514.11
solute carrier family 35 (UDP-galactose transporter), member A2
chr19_-_43376794 0.49 ENSMUST00000099428.5
heparanase 2
chrX_-_56438380 0.49 ENSMUST00000143310.2
ENSMUST00000098470.9
ENSMUST00000114726.8
RNA binding motif protein, X chromosome
chr3_-_61273228 0.49 ENSMUST00000066298.3
RIKEN cDNA B430305J03 gene
chr6_-_135145129 0.49 ENSMUST00000045855.9
heme binding protein 1
chr19_-_10859046 0.49 ENSMUST00000128835.8
transmembrane protein 109
chr16_+_26400454 0.49 ENSMUST00000096129.9
ENSMUST00000166294.9
ENSMUST00000174202.8
ENSMUST00000023156.13
interleukin 1 receptor accessory protein
chr8_+_84441806 0.49 ENSMUST00000019576.15
DEAD box helicase 39a
chr2_+_155223728 0.48 ENSMUST00000043237.14
ENSMUST00000174685.8
transformation related protein 53 inducible nuclear protein 2
chr9_-_96246460 0.48 ENSMUST00000034983.7
ATPase, Na+/K+ transporting, beta 3 polypeptide
chr7_-_44803859 0.47 ENSMUST00000210125.2
aldehyde dehydrogenase 16 family, member A1
chr19_-_44124252 0.47 ENSMUST00000026218.7
CWF19-like 1, cell cycle control (S. pombe)
chr2_-_38895586 0.47 ENSMUST00000080861.6
ribosomal protein L35
chr9_+_106158549 0.46 ENSMUST00000191434.2
POC1 centriolar protein A
chr2_+_76505619 0.45 ENSMUST00000111920.2
pleckstrin homology domain-containing, family A (phosphoinositide binding specific) member 3
chr2_+_105734975 0.45 ENSMUST00000037499.6
IMP1 inner mitochondrial membrane peptidase-like (S. cerevisiae)
chr13_+_55593116 0.44 ENSMUST00000001115.16
ENSMUST00000224995.2
ENSMUST00000225925.2
ENSMUST00000099482.5
ENSMUST00000224118.2
G protein-coupled receptor kinase 6
chr18_+_12261798 0.44 ENSMUST00000025270.8
RIO kinase 3
chr4_+_3940747 0.44 ENSMUST00000119403.2
coiled-coil-helix-coiled-coil-helix domain containing 7
chrX_-_103457431 0.44 ENSMUST00000033695.6
ATP-binding cassette, sub-family B (MDR/TAP), member 7
chr7_+_45224524 0.44 ENSMUST00000210811.2
branched chain aminotransferase 2, mitochondrial
chr17_+_28059129 0.43 ENSMUST00000233657.2
U1 small nuclear ribonucleoprotein C
chr6_+_86605146 0.43 ENSMUST00000043400.9
aspartic peptidase, retroviral-like 1
chr14_+_75368939 0.43 ENSMUST00000125833.8
ENSMUST00000124499.8
lymphocyte cytosolic protein 1
chr5_+_3393893 0.42 ENSMUST00000165117.8
ENSMUST00000197385.2
cyclin-dependent kinase 6
chr2_-_163592127 0.42 ENSMUST00000017841.4
adenosine deaminase
chr11_-_82719850 0.42 ENSMUST00000021036.13
ENSMUST00000074515.11
ENSMUST00000103218.3
ring finger and FYVE like domain containing protein
chr9_-_36637670 0.41 ENSMUST00000172702.9
ENSMUST00000172742.2
checkpoint kinase 1
chr4_+_126156118 0.40 ENSMUST00000030660.9
trafficking protein particle complex 3
chr15_-_89476057 0.40 ENSMUST00000094056.12
ENSMUST00000023294.15
RAB, member RAS oncogene family-like 2
chr8_+_94941192 0.40 ENSMUST00000079961.14
ENSMUST00000212824.2
nucleoporin 93
chr6_-_124806430 0.40 ENSMUST00000047510.10
ubiquitin specific peptidase 5 (isopeptidase T)
chr7_-_120269462 0.39 ENSMUST00000127845.2
ENSMUST00000208635.2
ENSMUST00000033178.4
PDZ domain containing 9
chr8_+_85598734 0.39 ENSMUST00000170296.2
ENSMUST00000136026.8
synaptonemal complex central element protein 2
chr9_-_36637923 0.39 ENSMUST00000034625.12
checkpoint kinase 1
chr5_-_139330906 0.38 ENSMUST00000049630.13
cytochrome c oxidase assembly protein 19
chr8_-_78337297 0.38 ENSMUST00000141202.2
ENSMUST00000152168.8
transmembrane protein 184C
chr11_-_76737794 0.38 ENSMUST00000021201.6
carboxypeptidase D
chr11_+_76297969 0.38 ENSMUST00000021203.7
ENSMUST00000152183.2
translocase of inner mitochondrial membrane 22
chr6_+_34361153 0.37 ENSMUST00000038383.14
ENSMUST00000115051.8
aldo-keto reductase family 1, member B10 (aldose reductase)
chr14_-_55881257 0.37 ENSMUST00000122358.8
transmembrane 9 superfamily member 1
chr9_-_107971729 0.36 ENSMUST00000193254.6
acylpeptide hydrolase
chr7_-_4661980 0.36 ENSMUST00000205374.2
ENSMUST00000064099.8
protein phosphatase 6, regulatory subunit 1
chr10_+_81104006 0.36 ENSMUST00000057798.9
ENSMUST00000219304.2
amyloid beta (A4) precursor protein-binding, family A, member 3
chr7_+_101312840 0.35 ENSMUST00000001884.14
ClpB caseinolytic peptidase B
chr12_-_25147139 0.35 ENSMUST00000221761.2
inhibitor of DNA binding 2
chr1_+_74430575 0.35 ENSMUST00000027367.14
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase 1
chr17_-_22152003 0.35 ENSMUST00000074295.8
zinc finger protein 942
chr4_+_155887978 0.35 ENSMUST00000030942.13
ENSMUST00000185148.8
ENSMUST00000130188.2
mitochondrial ribosomal protein L20
chr1_-_72323464 0.35 ENSMUST00000027381.13
peroxisomal trans-2-enoyl-CoA reductase
chr2_+_24839758 0.35 ENSMUST00000028350.9
zinc finger, MYND domain containing 19
chr9_+_63509925 0.34 ENSMUST00000041551.9
alpha- and gamma-adaptin binding protein
chr7_-_127593003 0.34 ENSMUST00000033056.5
PYD and CARD domain containing
chr10_-_89568106 0.34 ENSMUST00000020109.5
ARP6 actin-related protein 6
chr13_+_21363602 0.34 ENSMUST00000222544.2
tripartite motif-containing 27
chr13_-_48779072 0.34 ENSMUST00000035824.11
protein tyrosine phosphatase domain containing 1
chrX_+_100683662 0.34 ENSMUST00000119299.8
ENSMUST00000044475.5
O-linked N-acetylglucosamine (GlcNAc) transferase (UDP-N-acetylglucosamine:polypeptide-N-acetylglucosaminyl transferase)
chr18_+_67221287 0.33 ENSMUST00000025402.15
guanine nucleotide binding protein, alpha stimulating, olfactory type
chr9_-_57552844 0.33 ENSMUST00000216979.2
ENSMUST00000034863.8
c-src tyrosine kinase
chr7_+_64042393 0.33 ENSMUST00000037205.11
methylmalonyl CoA epimerase
chr15_-_80148477 0.33 ENSMUST00000052499.9
ribosomal protein S19 binding protein 1
chr14_-_67953035 0.33 ENSMUST00000163100.8
ENSMUST00000132705.8
ENSMUST00000124045.3
cell division cycle associated 2
chr5_+_31398208 0.33 ENSMUST00000202576.4
ENSMUST00000031034.12
ENSMUST00000202842.4
ENSMUST00000201259.4
ENSMUST00000202505.2
nuclear receptor binding protein 1
chr17_-_66258110 0.33 ENSMUST00000233580.2
ENSMUST00000024906.6
twisted gastrulation BMP signaling modulator 1
chr7_+_12568647 0.32 ENSMUST00000004614.15
zinc finger protein 110
chr17_-_26288447 0.32 ENSMUST00000122103.9
ENSMUST00000120691.9
RAB11 family interacting protein 3 (class II)
chr6_+_136900830 0.32 ENSMUST00000204627.3
phosphodiesterase 6H, cGMP-specific, cone, gamma
chr9_+_95739747 0.32 ENSMUST00000215311.2
ataxia telangiectasia and Rad3 related
chr13_-_63579497 0.31 ENSMUST00000160931.2
ENSMUST00000099444.10
ENSMUST00000220684.2
ENSMUST00000161977.8
ENSMUST00000163091.8
Fanconi anemia, complementation group C
chr6_-_124806359 0.31 ENSMUST00000142058.8
ENSMUST00000122110.8
ubiquitin specific peptidase 5 (isopeptidase T)
chr3_-_131065658 0.31 ENSMUST00000029610.9
hydroxyacyl-Coenzyme A dehydrogenase
chr8_+_125589772 0.31 ENSMUST00000034466.10
ENSMUST00000161986.2
glyceronephosphate O-acyltransferase
chr1_+_170472092 0.31 ENSMUST00000046792.9
olfactomedin-like 2B
chrX_+_149372903 0.31 ENSMUST00000080884.11
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1
chr14_+_79689230 0.31 ENSMUST00000100359.3
ENSMUST00000226192.2
kelch repeat and BTB (POZ) domain containing 6
chr12_+_8724681 0.31 ENSMUST00000168361.8
ENSMUST00000169750.8
ENSMUST00000163730.8
pumilio RNA-binding family member 2
chr19_-_29790352 0.30 ENSMUST00000099525.5
RAN binding protein 6
chr9_+_44238089 0.30 ENSMUST00000054708.5
dolichyl-phosphate (UDP-N-acetylglucosamine) acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase)
chr17_+_28059099 0.30 ENSMUST00000233752.2
U1 small nuclear ribonucleoprotein C
chr5_+_137627431 0.30 ENSMUST00000176667.8
leucine-rich repeats and calponin homology (CH) domain containing 4
chr1_+_190795198 0.30 ENSMUST00000076952.12
ENSMUST00000139340.8
ENSMUST00000078259.8
NSL1, MIS12 kinetochore complex component
chr9_-_71803354 0.30 ENSMUST00000184448.8
transcription factor 12
chr8_-_54091980 0.30 ENSMUST00000047768.11
nei like 3 (E. coli)
chr8_+_105951777 0.29 ENSMUST00000034361.10
RIKEN cDNA D230025D16 gene
chr2_+_154498917 0.28 ENSMUST00000044277.10
charged multivesicular body protein 4B
chr5_-_34326753 0.28 ENSMUST00000202409.2
ENSMUST00000202638.4
ENSMUST00000042954.11
ENSMUST00000202541.2
DNA polymerase N
HAUS augmin-like complex, subunit 3
chr1_+_92862432 0.28 ENSMUST00000117814.8
calpain 10
chr19_-_43512929 0.28 ENSMUST00000026196.14
glutamic-oxaloacetic transaminase 1, soluble
chr2_-_154734702 0.28 ENSMUST00000166171.8
ENSMUST00000161172.3
eukaryotic translation initiation factor 2, subunit 2 (beta)
chr4_+_102446883 0.28 ENSMUST00000097949.11
ENSMUST00000106901.2
phosphodiesterase 4B, cAMP specific
chr14_-_55108384 0.28 ENSMUST00000146642.2
homeodomain leucine zipper-encoding gene
chr12_+_4684620 0.27 ENSMUST00000217672.2
intersectin 2
chr9_-_44255456 0.27 ENSMUST00000077353.15
hydroxymethylbilane synthase
chr6_-_48817675 0.27 ENSMUST00000203265.3
ENSMUST00000205159.3
transmembrane protein 176B
chr7_+_44506731 0.27 ENSMUST00000098478.7
polynucleotide kinase 3'- phosphatase
chr9_-_106666329 0.27 ENSMUST00000046502.7
RAD54 like 2 (S. cerevisiae)

Network of associatons between targets according to the STRING database.

First level regulatory network of Hsfy2

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.5 GO:0046072 dTDP biosynthetic process(GO:0006233) dTDP metabolic process(GO:0046072)
0.4 3.2 GO:0018401 peptidyl-proline hydroxylation to 4-hydroxy-L-proline(GO:0018401)
0.3 1.4 GO:0015755 fructose transport(GO:0015755)
0.3 1.0 GO:0002331 pre-B cell allelic exclusion(GO:0002331)
0.3 1.1 GO:0046226 coumarin catabolic process(GO:0046226)
0.3 0.8 GO:0010767 regulation of transcription from RNA polymerase II promoter in response to UV-induced DNA damage(GO:0010767)
0.2 1.7 GO:0010989 negative regulation of low-density lipoprotein particle clearance(GO:0010989) negative regulation of Golgi to plasma membrane protein transport(GO:0042997) negative regulation of establishment of protein localization to plasma membrane(GO:0090005)
0.2 0.9 GO:0010899 regulation of phosphatidylcholine catabolic process(GO:0010899) receptor-mediated endocytosis of low-density lipoprotein particle involved in cholesterol transport(GO:0090118) positive regulation of lysosomal protein catabolic process(GO:1905167)
0.2 0.9 GO:1904868 telomerase catalytic core complex assembly(GO:1904868) regulation of telomerase catalytic core complex assembly(GO:1904882) positive regulation of telomerase catalytic core complex assembly(GO:1904884)
0.2 0.6 GO:0051344 negative regulation of cyclic-nucleotide phosphodiesterase activity(GO:0051344)
0.2 0.8 GO:0051311 meiotic metaphase I plate congression(GO:0043060) meiotic metaphase plate congression(GO:0051311)
0.2 0.6 GO:0046351 disaccharide biosynthetic process(GO:0046351)
0.2 1.0 GO:0006432 phenylalanyl-tRNA aminoacylation(GO:0006432)
0.2 1.4 GO:1900739 regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900739) positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:1900740)
0.2 0.2 GO:2000825 positive regulation of androgen receptor activity(GO:2000825)
0.2 1.2 GO:0019348 dolichol metabolic process(GO:0019348)
0.2 1.2 GO:0006627 protein processing involved in protein targeting to mitochondrion(GO:0006627)
0.2 0.5 GO:0036343 psychomotor behavior(GO:0036343)
0.2 0.7 GO:0001844 protein insertion into mitochondrial membrane involved in apoptotic signaling pathway(GO:0001844)
0.1 1.9 GO:0006488 dolichol-linked oligosaccharide biosynthetic process(GO:0006488)
0.1 0.4 GO:0010360 negative regulation of anion channel activity(GO:0010360)
0.1 0.7 GO:0006566 threonine metabolic process(GO:0006566)
0.1 0.4 GO:0006550 isoleucine catabolic process(GO:0006550)
0.1 0.4 GO:0036275 response to 5-fluorouracil(GO:0036275)
0.1 0.4 GO:0070256 germinal center B cell differentiation(GO:0002314) adenosine catabolic process(GO:0006154) negative regulation of circadian sleep/wake cycle, non-REM sleep(GO:0042323) hypoxanthine metabolic process(GO:0046100) hypoxanthine biosynthetic process(GO:0046101) purine deoxyribonucleoside metabolic process(GO:0046122) negative regulation of mucus secretion(GO:0070256)
0.1 0.5 GO:0036228 protein targeting to nuclear inner membrane(GO:0036228)
0.1 4.5 GO:0000027 ribosomal large subunit assembly(GO:0000027)
0.1 0.4 GO:0046491 L-methylmalonyl-CoA metabolic process(GO:0046491)
0.1 0.4 GO:0001966 thigmotaxis(GO:0001966)
0.1 0.9 GO:0036265 RNA (guanine-N7)-methylation(GO:0036265)
0.1 0.3 GO:1903173 phytol metabolic process(GO:0033306) fatty alcohol metabolic process(GO:1903173)
0.1 0.3 GO:0002588 myeloid dendritic cell activation involved in immune response(GO:0002277) positive regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II(GO:0002582) positive regulation of antigen processing and presentation of peptide antigen via MHC class II(GO:0002588)
0.1 0.6 GO:0008582 regulation of synaptic growth at neuromuscular junction(GO:0008582)
0.1 0.3 GO:0090526 regulation of gluconeogenesis involved in cellular glucose homeostasis(GO:0090526)
0.1 0.9 GO:0014835 myoblast differentiation involved in skeletal muscle regeneration(GO:0014835) positive regulation of interleukin-12 secretion(GO:2001184)
0.1 0.4 GO:2001271 negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:2001271)
0.1 0.5 GO:0070837 dehydroascorbic acid transport(GO:0070837)
0.1 0.5 GO:0042412 taurine biosynthetic process(GO:0042412)
0.1 1.5 GO:0070189 kynurenine metabolic process(GO:0070189)
0.1 0.5 GO:1903288 positive regulation of potassium ion import(GO:1903288)
0.1 0.3 GO:0006532 fumarate metabolic process(GO:0006106) aspartate biosynthetic process(GO:0006532) aspartate catabolic process(GO:0006533)
0.1 0.3 GO:0018160 peptidyl-pyrromethane cofactor linkage(GO:0018160)
0.1 1.1 GO:0060770 negative regulation of epithelial cell proliferation involved in prostate gland development(GO:0060770)
0.1 1.0 GO:0002002 regulation of angiotensin levels in blood(GO:0002002)
0.1 1.8 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.1 0.3 GO:0098501 polynucleotide dephosphorylation(GO:0098501)
0.1 0.8 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.1 0.3 GO:0071846 actin filament debranching(GO:0071846)
0.1 0.2 GO:0072356 chromosome passenger complex localization to kinetochore(GO:0072356)
0.1 0.2 GO:0071043 CUT catabolic process(GO:0071034) CUT metabolic process(GO:0071043)
0.1 0.7 GO:0006450 regulation of translational fidelity(GO:0006450)
0.1 0.4 GO:0045039 protein import into mitochondrial inner membrane(GO:0045039)
0.1 0.4 GO:0039534 negative regulation of MDA-5 signaling pathway(GO:0039534)
0.1 0.5 GO:1903094 regulation of protein K48-linked deubiquitination(GO:1903093) negative regulation of protein K48-linked deubiquitination(GO:1903094) negative regulation of ubiquitin-specific protease activity(GO:2000157)
0.1 0.2 GO:0009726 detection of nodal flow(GO:0003127) detection of endogenous stimulus(GO:0009726)
0.1 1.4 GO:0016226 iron-sulfur cluster assembly(GO:0016226) metallo-sulfur cluster assembly(GO:0031163)
0.1 0.7 GO:0098789 pre-mRNA cleavage required for polyadenylation(GO:0098789)
0.1 0.8 GO:0005981 regulation of glycogen catabolic process(GO:0005981)
0.1 0.2 GO:0072429 response to intra-S DNA damage checkpoint signaling(GO:0072429)
0.1 0.1 GO:0002859 negative regulation of natural killer cell mediated immune response to tumor cell(GO:0002856) negative regulation of natural killer cell mediated cytotoxicity directed against tumor cell target(GO:0002859)
0.1 0.2 GO:0006578 amino-acid betaine biosynthetic process(GO:0006578)
0.1 0.5 GO:0090170 regulation of Golgi inheritance(GO:0090170)
0.1 0.4 GO:0090521 glomerular visceral epithelial cell migration(GO:0090521)
0.1 0.2 GO:0002355 detection of tumor cell(GO:0002355)
0.1 0.3 GO:1900041 negative regulation of interleukin-2 secretion(GO:1900041)
0.1 1.3 GO:0000469 cleavage involved in rRNA processing(GO:0000469)
0.1 0.3 GO:0070164 negative regulation of adiponectin secretion(GO:0070164)
0.1 0.4 GO:0003431 growth plate cartilage chondrocyte development(GO:0003431)
0.1 0.5 GO:0000463 maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)(GO:0000463)
0.1 0.9 GO:0046498 S-adenosylhomocysteine metabolic process(GO:0046498)
0.0 0.3 GO:0090611 ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway(GO:0090611)
0.0 0.3 GO:2000562 negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562)
0.0 0.3 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.0 0.2 GO:0060414 aorta smooth muscle tissue morphogenesis(GO:0060414)
0.0 0.3 GO:1990009 retinal cell apoptotic process(GO:1990009)
0.0 0.3 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
0.0 0.3 GO:0006172 ADP biosynthetic process(GO:0006172)
0.0 1.1 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.0 1.7 GO:0006376 mRNA splice site selection(GO:0006376)
0.0 0.0 GO:1903281 positive regulation of calcium:sodium antiporter activity(GO:1903281)
0.0 0.5 GO:0072602 interleukin-4 secretion(GO:0072602)
0.0 1.0 GO:0033539 fatty acid beta-oxidation using acyl-CoA dehydrogenase(GO:0033539)
0.0 0.3 GO:1901503 ether lipid biosynthetic process(GO:0008611) glycerol ether biosynthetic process(GO:0046504) ether biosynthetic process(GO:1901503)
0.0 0.4 GO:0006610 ribosomal protein import into nucleus(GO:0006610)
0.0 2.0 GO:0046839 phospholipid dephosphorylation(GO:0046839)
0.0 0.2 GO:0002159 desmosome assembly(GO:0002159)
0.0 0.5 GO:0060330 regulation of response to interferon-gamma(GO:0060330)
0.0 3.4 GO:0032088 negative regulation of NF-kappaB transcription factor activity(GO:0032088)
0.0 0.4 GO:0009312 oligosaccharide biosynthetic process(GO:0009312)
0.0 0.5 GO:0090141 positive regulation of mitochondrial fission(GO:0090141)
0.0 0.3 GO:0006003 fructose 2,6-bisphosphate metabolic process(GO:0006003)
0.0 0.5 GO:0006120 mitochondrial electron transport, NADH to ubiquinone(GO:0006120)
0.0 0.1 GO:0033030 negative regulation of neutrophil apoptotic process(GO:0033030) interleukin-13 biosynthetic process(GO:0042231)
0.0 0.4 GO:2001199 negative regulation of dendritic cell differentiation(GO:2001199)
0.0 0.2 GO:0031179 peptide modification(GO:0031179)
0.0 0.5 GO:2001256 regulation of store-operated calcium entry(GO:2001256)
0.0 1.4 GO:0019835 cytolysis(GO:0019835)
0.0 0.6 GO:0071803 positive regulation of podosome assembly(GO:0071803)
0.0 0.4 GO:0006517 protein deglycosylation(GO:0006517)
0.0 0.1 GO:0039019 pronephric nephron development(GO:0039019)
0.0 0.1 GO:0003032 detection of oxygen(GO:0003032)
0.0 1.0 GO:0042168 heme metabolic process(GO:0042168)
0.0 0.7 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.1 GO:0006269 DNA replication, synthesis of RNA primer(GO:0006269)
0.0 0.1 GO:0036414 protein citrullination(GO:0018101) histone citrullination(GO:0036414)
0.0 0.3 GO:1901898 negative regulation of relaxation of cardiac muscle(GO:1901898)
0.0 0.8 GO:0050832 defense response to fungus(GO:0050832)
0.0 0.0 GO:0002439 chronic inflammatory response to antigenic stimulus(GO:0002439) regulation of chronic inflammatory response to antigenic stimulus(GO:0002874)
0.0 1.0 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.0 0.1 GO:1903413 response to bile acid(GO:1903412) cellular response to bile acid(GO:1903413)
0.0 0.6 GO:0034308 primary alcohol metabolic process(GO:0034308)
0.0 0.2 GO:0034501 protein localization to kinetochore(GO:0034501)
0.0 0.7 GO:0048147 negative regulation of fibroblast proliferation(GO:0048147)
0.0 0.4 GO:0007130 synaptonemal complex assembly(GO:0007130)
0.0 0.1 GO:0016480 negative regulation of transcription from RNA polymerase III promoter(GO:0016480)
0.0 0.1 GO:0030951 establishment or maintenance of microtubule cytoskeleton polarity(GO:0030951) positive regulation of cell aging(GO:0090343)
0.0 1.0 GO:0050435 beta-amyloid metabolic process(GO:0050435)
0.0 0.3 GO:0019430 removal of superoxide radicals(GO:0019430)
0.0 0.1 GO:1902528 regulation of protein linear polyubiquitination(GO:1902528) positive regulation of protein linear polyubiquitination(GO:1902530)
0.0 0.8 GO:0045737 positive regulation of cyclin-dependent protein serine/threonine kinase activity(GO:0045737)
0.0 0.3 GO:0034063 stress granule assembly(GO:0034063)
0.0 0.3 GO:0002176 male germ cell proliferation(GO:0002176)
0.0 0.6 GO:0030490 maturation of SSU-rRNA(GO:0030490)
0.0 0.1 GO:1903608 protein localization to cytoplasmic stress granule(GO:1903608)
0.0 0.3 GO:0048934 peripheral nervous system neuron differentiation(GO:0048934) peripheral nervous system neuron development(GO:0048935)
0.0 0.9 GO:0006695 cholesterol biosynthetic process(GO:0006695)
0.0 1.0 GO:0002181 cytoplasmic translation(GO:0002181)
0.0 0.1 GO:0000492 box C/D snoRNP assembly(GO:0000492)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.8 GO:0016222 procollagen-proline 4-dioxygenase complex(GO:0016222)
0.3 1.0 GO:1990423 RZZ complex(GO:1990423)
0.3 1.0 GO:0009328 phenylalanine-tRNA ligase complex(GO:0009328)
0.3 0.9 GO:1990666 PCSK9-LDLR complex(GO:1990666)
0.3 0.8 GO:0005712 chiasma(GO:0005712)
0.3 1.1 GO:0017133 mitochondrial electron transfer flavoprotein complex(GO:0017133) electron transfer flavoprotein complex(GO:0045251)
0.2 0.6 GO:0034457 Mpp10 complex(GO:0034457)
0.2 1.1 GO:0033588 Elongator holoenzyme complex(GO:0033588)
0.2 0.9 GO:0043527 tRNA methyltransferase complex(GO:0043527)
0.1 0.4 GO:0042720 mitochondrial inner membrane peptidase complex(GO:0042720)
0.1 0.4 GO:0097132 cyclin D2-CDK6 complex(GO:0097132)
0.1 0.6 GO:0034751 aryl hydrocarbon receptor complex(GO:0034751)
0.1 0.4 GO:0042721 mitochondrial inner membrane protein insertion complex(GO:0042721)
0.1 3.6 GO:0005689 U12-type spliceosomal complex(GO:0005689)
0.1 0.5 GO:0000444 MIS12/MIND type complex(GO:0000444)
0.1 1.1 GO:0005750 mitochondrial respiratory chain complex III(GO:0005750)
0.1 0.3 GO:0043540 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex(GO:0043540)
0.1 0.8 GO:0000243 commitment complex(GO:0000243)
0.1 1.2 GO:0071004 U2-type prespliceosome(GO:0071004)
0.1 0.8 GO:0072357 PTW/PP1 phosphatase complex(GO:0072357)
0.1 1.3 GO:0043203 axon hillock(GO:0043203)
0.1 0.3 GO:0097169 AIM2 inflammasome complex(GO:0097169)
0.1 0.7 GO:0070847 core mediator complex(GO:0070847)
0.1 0.5 GO:0044530 supraspliceosomal complex(GO:0044530)
0.1 2.1 GO:0005839 proteasome core complex(GO:0005839)
0.1 0.6 GO:0005785 signal recognition particle receptor complex(GO:0005785)
0.1 0.2 GO:0016939 kinesin II complex(GO:0016939)
0.1 0.5 GO:0044611 nuclear pore inner ring(GO:0044611)
0.1 5.4 GO:0022625 cytosolic large ribosomal subunit(GO:0022625)
0.1 0.5 GO:0005850 eukaryotic translation initiation factor 2 complex(GO:0005850)
0.0 0.5 GO:0005890 sodium:potassium-exchanging ATPase complex(GO:0005890)
0.0 3.4 GO:0005758 mitochondrial intermembrane space(GO:0005758)
0.0 0.2 GO:0048476 Holliday junction resolvase complex(GO:0048476)
0.0 0.4 GO:0030688 preribosome, small subunit precursor(GO:0030688)
0.0 0.4 GO:0000801 central element(GO:0000801)
0.0 0.3 GO:0070652 HAUS complex(GO:0070652)
0.0 0.5 GO:0034098 VCP-NPL4-UFD1 AAA ATPase complex(GO:0034098)
0.0 0.8 GO:0005838 proteasome regulatory particle(GO:0005838)
0.0 0.6 GO:0005847 mRNA cleavage and polyadenylation specificity factor complex(GO:0005847)
0.0 0.2 GO:0098553 integral component of cytoplasmic side of endoplasmic reticulum membrane(GO:0071458) integral component of lumenal side of endoplasmic reticulum membrane(GO:0071556) lumenal side of endoplasmic reticulum membrane(GO:0098553)
0.0 1.0 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 1.1 GO:0032839 dendrite cytoplasm(GO:0032839)
0.0 0.5 GO:0030687 preribosome, large subunit precursor(GO:0030687)
0.0 1.0 GO:0030686 90S preribosome(GO:0030686)
0.0 1.6 GO:0005762 organellar large ribosomal subunit(GO:0000315) mitochondrial large ribosomal subunit(GO:0005762)
0.0 0.3 GO:0000815 ESCRT III complex(GO:0000815)
0.0 0.1 GO:1990246 uniplex complex(GO:1990246)
0.0 0.9 GO:0001741 XY body(GO:0001741)
0.0 0.1 GO:0071008 U2-type post-mRNA release spliceosomal complex(GO:0071008)
0.0 1.1 GO:0015030 Cajal body(GO:0015030)
0.0 0.5 GO:0002080 acrosomal membrane(GO:0002080)
0.0 0.2 GO:0005583 fibrillar collagen trimer(GO:0005583) banded collagen fibril(GO:0098643)
0.0 0.6 GO:0001891 phagocytic cup(GO:0001891)
0.0 0.4 GO:0030008 TRAPP complex(GO:0030008)
0.0 0.9 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.3 GO:0043240 Fanconi anaemia nuclear complex(GO:0043240)
0.0 0.1 GO:0005726 perichromatin fibrils(GO:0005726)
0.0 0.1 GO:0030289 protein phosphatase 4 complex(GO:0030289)
0.0 0.1 GO:0005638 lamin filament(GO:0005638)
0.0 0.1 GO:0097165 nuclear stress granule(GO:0097165)
0.0 0.2 GO:0033180 proton-transporting V-type ATPase, V1 domain(GO:0033180)
0.0 0.2 GO:0000176 nuclear exosome (RNase complex)(GO:0000176)
0.0 0.0 GO:0090533 cation-transporting ATPase complex(GO:0090533)
0.0 0.1 GO:0005658 alpha DNA polymerase:primase complex(GO:0005658)
0.0 1.2 GO:0019005 SCF ubiquitin ligase complex(GO:0019005)
0.0 0.4 GO:0030992 intraciliary transport particle B(GO:0030992)
0.0 0.1 GO:0035327 transcriptionally active chromatin(GO:0035327)
0.0 0.3 GO:0031907 peroxisomal matrix(GO:0005782) microbody lumen(GO:0031907)
0.0 0.8 GO:0005657 replication fork(GO:0005657)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.8 2.5 GO:0004798 thymidylate kinase activity(GO:0004798)
0.5 1.5 GO:0015292 uniporter activity(GO:0015292)
0.4 1.1 GO:0046573 lactonohydrolase activity(GO:0046573) acyl-L-homoserine-lactone lactonohydrolase activity(GO:0102007)
0.3 4.9 GO:0008097 5S rRNA binding(GO:0008097)
0.3 1.5 GO:0047804 cysteine-S-conjugate beta-lyase activity(GO:0047804)
0.3 1.8 GO:0004656 procollagen-proline 4-dioxygenase activity(GO:0004656)
0.3 1.8 GO:0032450 maltose alpha-glucosidase activity(GO:0032450)
0.3 1.1 GO:0005459 UDP-galactose transmembrane transporter activity(GO:0005459)
0.2 0.9 GO:0008176 tRNA (guanine-N7-)-methyltransferase activity(GO:0008176)
0.2 1.4 GO:0031545 peptidyl-proline 4-dioxygenase activity(GO:0031545)
0.2 1.1 GO:0010484 H3 histone acetyltransferase activity(GO:0010484)
0.2 1.7 GO:0032407 MutSalpha complex binding(GO:0032407)
0.2 0.6 GO:0036004 GAF domain binding(GO:0036004)
0.2 0.8 GO:0035402 histone kinase activity (H3-T11 specific)(GO:0035402)
0.2 0.8 GO:1990932 5.8S rRNA binding(GO:1990932)
0.2 0.8 GO:0030627 pre-mRNA 5'-splice site binding(GO:0030627)
0.2 0.7 GO:0008732 threonine aldolase activity(GO:0004793) L-allo-threonine aldolase activity(GO:0008732)
0.2 0.5 GO:0003870 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.2 0.8 GO:0004719 protein-L-isoaspartate (D-aspartate) O-methyltransferase activity(GO:0004719)
0.2 1.0 GO:0004826 phenylalanine-tRNA ligase activity(GO:0004826)
0.1 0.8 GO:0061575 cyclin-dependent protein serine/threonine kinase activator activity(GO:0061575)
0.1 0.9 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.1 2.0 GO:0042577 lipid phosphatase activity(GO:0042577)
0.1 0.4 GO:0030943 mitochondrion targeting sequence binding(GO:0030943)
0.1 0.5 GO:0071796 K6-linked polyubiquitin binding(GO:0071796)
0.1 1.2 GO:0050733 RS domain binding(GO:0050733)
0.1 0.4 GO:0070401 NADP+ binding(GO:0070401)
0.1 0.5 GO:0002114 interleukin-33 receptor activity(GO:0002114)
0.1 0.4 GO:0004493 methylmalonyl-CoA epimerase activity(GO:0004493)
0.1 0.9 GO:0030229 very-low-density lipoprotein particle receptor activity(GO:0030229)
0.1 0.3 GO:0032090 Pyrin domain binding(GO:0032090)
0.1 0.3 GO:0016262 protein N-acetylglucosaminyltransferase activity(GO:0016262)
0.1 0.4 GO:0098770 FBXO family protein binding(GO:0098770)
0.1 0.5 GO:0055056 dehydroascorbic acid transporter activity(GO:0033300) D-glucose transmembrane transporter activity(GO:0055056)
0.1 0.6 GO:0005047 signal recognition particle binding(GO:0005047)
0.1 0.3 GO:0080130 L-aspartate:2-oxoglutarate aminotransferase activity(GO:0004069) L-phenylalanine aminotransferase activity(GO:0070546) L-phenylalanine:2-oxoglutarate aminotransferase activity(GO:0080130)
0.1 0.3 GO:0004418 hydroxymethylbilane synthase activity(GO:0004418)
0.1 0.3 GO:0046899 nucleoside triphosphate adenylate kinase activity(GO:0046899)
0.1 0.3 GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity(GO:0019166)
0.1 1.0 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.1 2.1 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1 0.3 GO:0003976 UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase activity(GO:0003976)
0.1 1.7 GO:0034236 protein kinase A catalytic subunit binding(GO:0034236)
0.1 2.5 GO:0051537 2 iron, 2 sulfur cluster binding(GO:0051537)
0.1 0.6 GO:0004768 stearoyl-CoA 9-desaturase activity(GO:0004768)
0.1 0.5 GO:0004782 sulfinoalanine decarboxylase activity(GO:0004782)
0.1 0.3 GO:0046403 polynucleotide 3'-phosphatase activity(GO:0046403)
0.1 0.4 GO:0089720 caspase binding(GO:0089720)
0.1 0.2 GO:0072354 histone kinase activity (H3-T3 specific)(GO:0072354)
0.1 0.6 GO:0008889 glycerophosphodiester phosphodiesterase activity(GO:0008889)
0.1 0.9 GO:0050308 sugar-phosphatase activity(GO:0050308)
0.1 0.9 GO:0051525 NFAT protein binding(GO:0051525)
0.1 0.2 GO:0016842 amidine-lyase activity(GO:0016842)
0.1 1.0 GO:0008242 omega peptidase activity(GO:0008242)
0.1 0.4 GO:0052656 branched-chain-amino-acid transaminase activity(GO:0004084) L-leucine transaminase activity(GO:0052654) L-valine transaminase activity(GO:0052655) L-isoleucine transaminase activity(GO:0052656)
0.0 0.2 GO:0048763 calcium-induced calcium release activity(GO:0048763)
0.0 0.5 GO:0008494 translation activator activity(GO:0008494)
0.0 1.4 GO:0004181 metallocarboxypeptidase activity(GO:0004181)
0.0 0.3 GO:0004832 valine-tRNA ligase activity(GO:0004832)
0.0 0.9 GO:0004659 prenyltransferase activity(GO:0004659)
0.0 0.3 GO:0000405 bubble DNA binding(GO:0000405)
0.0 0.6 GO:0046527 glucosyltransferase activity(GO:0046527)
0.0 0.2 GO:0001032 RNA polymerase III type 3 promoter DNA binding(GO:0001032)
0.0 0.3 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.0 0.5 GO:0005391 sodium:potassium-exchanging ATPase activity(GO:0005391)
0.0 0.4 GO:0001665 alpha-N-acetylgalactosaminide alpha-2,6-sialyltransferase activity(GO:0001665)
0.0 0.3 GO:0030306 ADP-ribosylation factor binding(GO:0030306)
0.0 0.3 GO:0008420 CTD phosphatase activity(GO:0008420)
0.0 0.3 GO:0003857 3-hydroxyacyl-CoA dehydrogenase activity(GO:0003857)
0.0 0.3 GO:0016413 O-acetyltransferase activity(GO:0016413)
0.0 0.4 GO:0004000 adenosine deaminase activity(GO:0004000)
0.0 0.9 GO:0017056 structural constituent of nuclear pore(GO:0017056)
0.0 0.1 GO:0003896 DNA primase activity(GO:0003896)
0.0 0.2 GO:0048256 flap endonuclease activity(GO:0048256)
0.0 1.0 GO:0042605 peptide antigen binding(GO:0042605)
0.0 3.4 GO:0043130 ubiquitin binding(GO:0043130)
0.0 0.5 GO:0004708 MAP kinase kinase activity(GO:0004708)
0.0 0.1 GO:0004668 protein-arginine deiminase activity(GO:0004668)
0.0 0.1 GO:0031727 CCR2 chemokine receptor binding(GO:0031727)
0.0 1.2 GO:0004521 endoribonuclease activity(GO:0004521)
0.0 0.2 GO:0061676 importin-alpha family protein binding(GO:0061676)
0.0 0.3 GO:0071933 Arp2/3 complex binding(GO:0071933)
0.0 0.6 GO:0004602 glutathione peroxidase activity(GO:0004602)
0.0 0.5 GO:0004029 aldehyde dehydrogenase (NAD) activity(GO:0004029)
0.0 0.3 GO:0035497 cAMP response element binding(GO:0035497)
0.0 0.4 GO:0008139 nuclear localization sequence binding(GO:0008139)
0.0 0.2 GO:0048407 platelet-derived growth factor binding(GO:0048407)
0.0 0.4 GO:0004190 aspartic-type endopeptidase activity(GO:0004190)
0.0 0.1 GO:0005049 nuclear export signal receptor activity(GO:0005049)
0.0 0.3 GO:0030553 cGMP binding(GO:0030553)
0.0 0.1 GO:0004784 superoxide dismutase activity(GO:0004784) oxidoreductase activity, acting on superoxide radicals as acceptor(GO:0016721)
0.0 0.9 GO:0004722 protein serine/threonine phosphatase activity(GO:0004722)
0.0 0.4 GO:0070273 phosphatidylinositol-4-phosphate binding(GO:0070273)
0.0 1.2 GO:0050660 flavin adenine dinucleotide binding(GO:0050660)
0.0 0.4 GO:0031492 nucleosomal DNA binding(GO:0031492)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 0.8 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.1 1.4 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.7 SA FAS SIGNALING The TNF-type receptor Fas induces apoptosis on ligand binding.
0.0 0.9 PID CIRCADIAN PATHWAY Circadian rhythm pathway
0.0 3.0 ST T CELL SIGNAL TRANSDUCTION T Cell Signal Transduction
0.0 0.9 PID NFKAPPAB ATYPICAL PATHWAY Atypical NF-kappaB pathway
0.0 0.5 PID TCR RAS PATHWAY Ras signaling in the CD4+ TCR pathway
0.0 0.4 PID TNF PATHWAY TNF receptor signaling pathway
0.0 1.2 PID TAP63 PATHWAY Validated transcriptional targets of TAp63 isoforms
0.0 2.0 ST INTEGRIN SIGNALING PATHWAY Integrin Signaling Pathway
0.0 0.3 PID SMAD2 3PATHWAY Regulation of cytoplasmic and nuclear SMAD2/3 signaling
0.0 0.3 PID ARF6 DOWNSTREAM PATHWAY Arf6 downstream pathway
0.0 0.7 PID PLK1 PATHWAY PLK1 signaling events
0.0 0.3 PID P38 MK2 PATHWAY p38 signaling mediated by MAPKAP kinases
0.0 0.9 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.0 0.4 PID CONE PATHWAY Visual signal transduction: Cones
0.0 0.5 PID IL1 PATHWAY IL1-mediated signaling events
0.0 0.6 NABA BASEMENT MEMBRANES Genes encoding structural components of basement membranes
0.0 0.4 PID IL2 STAT5 PATHWAY IL2 signaling events mediated by STAT5
0.0 1.7 PID P53 DOWNSTREAM PATHWAY Direct p53 effectors

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.5 1.8 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.1 1.7 REACTOME G2 M DNA DAMAGE CHECKPOINT Genes involved in G2/M DNA damage checkpoint
0.1 1.9 REACTOME FACILITATIVE NA INDEPENDENT GLUCOSE TRANSPORTERS Genes involved in Facilitative Na+-independent glucose transporters
0.1 2.8 REACTOME CHYLOMICRON MEDIATED LIPID TRANSPORT Genes involved in Chylomicron-mediated lipid transport
0.1 1.4 REACTOME OXYGEN DEPENDENT PROLINE HYDROXYLATION OF HYPOXIA INDUCIBLE FACTOR ALPHA Genes involved in Oxygen-dependent Proline Hydroxylation of Hypoxia-inducible Factor Alpha
0.1 2.5 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.1 3.5 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.1 1.1 REACTOME DESTABILIZATION OF MRNA BY KSRP Genes involved in Destabilization of mRNA by KSRP
0.1 2.9 REACTOME AUTODEGRADATION OF THE E3 UBIQUITIN LIGASE COP1 Genes involved in Autodegradation of the E3 ubiquitin ligase COP1
0.0 5.7 REACTOME PEPTIDE CHAIN ELONGATION Genes involved in Peptide chain elongation
0.0 1.4 REACTOME ACTIVATION OF BH3 ONLY PROTEINS Genes involved in Activation of BH3-only proteins
0.0 1.3 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 0.7 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.5 REACTOME RAF MAP KINASE CASCADE Genes involved in RAF/MAP kinase cascade
0.0 1.7 REACTOME INTEGRIN ALPHAIIB BETA3 SIGNALING Genes involved in Integrin alphaIIb beta3 signaling
0.0 0.8 REACTOME METABOLISM OF PORPHYRINS Genes involved in Metabolism of porphyrins
0.0 2.4 REACTOME RESPIRATORY ELECTRON TRANSPORT Genes involved in Respiratory electron transport
0.0 0.9 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.8 REACTOME HORMONE SENSITIVE LIPASE HSL MEDIATED TRIACYLGLYCEROL HYDROLYSIS Genes involved in Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis
0.0 0.9 REACTOME BIOSYNTHESIS OF THE N GLYCAN PRECURSOR DOLICHOL LIPID LINKED OLIGOSACCHARIDE LLO AND TRANSFER TO A NASCENT PROTEIN Genes involved in Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein
0.0 1.2 REACTOME GLUCONEOGENESIS Genes involved in Gluconeogenesis
0.0 0.5 REACTOME HS GAG DEGRADATION Genes involved in HS-GAG degradation
0.0 0.9 REACTOME TRANSPORT OF RIBONUCLEOPROTEINS INTO THE HOST NUCLEUS Genes involved in Transport of Ribonucleoproteins into the Host Nucleus
0.0 0.8 REACTOME MEIOTIC RECOMBINATION Genes involved in Meiotic Recombination
0.0 0.3 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 1.1 REACTOME TRANSPORT OF VITAMINS NUCLEOSIDES AND RELATED MOLECULES Genes involved in Transport of vitamins, nucleosides, and related molecules
0.0 0.7 REACTOME SRP DEPENDENT COTRANSLATIONAL PROTEIN TARGETING TO MEMBRANE Genes involved in SRP-dependent cotranslational protein targeting to membrane
0.0 0.4 REACTOME BRANCHED CHAIN AMINO ACID CATABOLISM Genes involved in Branched-chain amino acid catabolism
0.0 0.3 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.4 REACTOME PURINE SALVAGE Genes involved in Purine salvage
0.0 0.5 REACTOME SULFUR AMINO ACID METABOLISM Genes involved in Sulfur amino acid metabolism
0.0 1.5 REACTOME MITOTIC PROMETAPHASE Genes involved in Mitotic Prometaphase
0.0 0.1 REACTOME INHIBITION OF REPLICATION INITIATION OF DAMAGED DNA BY RB1 E2F1 Genes involved in Inhibition of replication initiation of damaged DNA by RB1/E2F1
0.0 0.1 REACTOME DESTABILIZATION OF MRNA BY TRISTETRAPROLIN TTP Genes involved in Destabilization of mRNA by Tristetraprolin (TTP)
0.0 0.6 REACTOME MRNA SPLICING MINOR PATHWAY Genes involved in mRNA Splicing - Minor Pathway
0.0 0.2 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle