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avrg: GFI1 WT vs 36n/n vs KD

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Results for Irf2_Irf1_Irf8_Irf9_Irf7

Z-value: 1.48

Motif logo

Transcription factors associated with Irf2_Irf1_Irf8_Irf9_Irf7

Gene Symbol Gene ID Gene Info
ENSMUSG00000031627.10 interferon regulatory factor 2
ENSMUSG00000018899.18 interferon regulatory factor 1
ENSMUSG00000041515.11 interferon regulatory factor 8
ENSMUSG00000002325.16 interferon regulatory factor 9
ENSMUSG00000025498.16 interferon regulatory factor 7

Activity-expression correlation:

Activity profile of Irf2_Irf1_Irf8_Irf9_Irf7 motif

Sorted Z-values of Irf2_Irf1_Irf8_Irf9_Irf7 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr3_+_142326363 4.08 ENSMUST00000165774.8
guanylate binding protein 2
chr11_+_48977852 2.04 ENSMUST00000046704.7
ENSMUST00000203810.3
ENSMUST00000203149.3
interferon gamma inducible protein 47
olfactory receptor 56
chr12_+_103400470 1.68 ENSMUST00000079294.12
ENSMUST00000076788.12
ENSMUST00000076702.12
ENSMUST00000066701.13
ENSMUST00000085065.12
ENSMUST00000140838.2
interferon, alpha-inducible protein 27
chr17_-_36353582 1.42 ENSMUST00000058801.15
ENSMUST00000080015.12
ENSMUST00000077960.7
histocompatibility 2, T region locus 22
chr18_+_60880149 1.40 ENSMUST00000236652.2
ENSMUST00000235966.2
ribosomal protein S14
chr11_+_48977888 1.35 ENSMUST00000214804.2
interferon gamma inducible protein 47
chr17_-_34406193 1.35 ENSMUST00000173831.3
proteasome (prosome, macropain) subunit, beta type 9 (large multifunctional peptidase 2)
chr11_-_48762170 1.29 ENSMUST00000049519.4
ENSMUST00000097271.4
immunity-related GTPase family M member 1
chr8_+_62381115 1.27 ENSMUST00000154398.8
ENSMUST00000156980.8
ENSMUST00000093485.3
ENSMUST00000070631.15
DExD/H box helicase 60
chr11_-_48883053 1.23 ENSMUST00000059930.3
ENSMUST00000068063.4
predicted gene 12185
T cell specific GTPase 1
chr2_-_51863203 1.17 ENSMUST00000028314.9
N-myc (and STAT) interactor
chr11_-_48955028 1.14 ENSMUST00000046745.7
T cell specific GTPase 2
chr2_-_105229653 1.10 ENSMUST00000006128.7
reticulocalbin 1
chr4_-_40239778 1.09 ENSMUST00000037907.13
DEAD/H box helicase 58
chr15_-_76127600 1.03 ENSMUST00000165738.8
ENSMUST00000075689.7
poly (ADP-ribose) polymerase family, member 10
chr5_-_92496730 0.98 ENSMUST00000038816.13
ENSMUST00000118006.3
chemokine (C-X-C motif) ligand 10
chr6_+_121222865 0.88 ENSMUST00000032198.11
ubiquitin specific peptidase 18
chr3_+_142265787 0.87 ENSMUST00000199325.5
ENSMUST00000106222.9
guanylate binding protein 3
chr6_+_57557978 0.87 ENSMUST00000031817.10
hect domain and RLD 6
chr6_+_127423779 0.86 ENSMUST00000112191.8
poly (ADP-ribose) polymerase family, member 11
chr3_+_142265904 0.86 ENSMUST00000128609.8
ENSMUST00000029935.14
guanylate binding protein 3
chr3_+_27371168 0.85 ENSMUST00000046383.12
tumor necrosis factor (ligand) superfamily, member 10
chr3_+_142266113 0.84 ENSMUST00000106221.8
guanylate binding protein 3
chr11_+_119283887 0.84 ENSMUST00000093902.12
ENSMUST00000131035.10
ring finger protein 213
chr16_+_35759346 0.83 ENSMUST00000023622.13
poly (ADP-ribose) polymerase family, member 9
chr17_+_35658131 0.83 ENSMUST00000071951.14
ENSMUST00000116598.10
ENSMUST00000078205.14
ENSMUST00000076256.8
histocompatibility 2, Q region locus 7
chr5_-_105441554 0.82 ENSMUST00000050011.10
ENSMUST00000196520.2
predicted gene 43302
guanylate binding protein 6
chr19_+_56385531 0.80 ENSMUST00000026062.10
caspase 7
chr3_+_142236086 0.80 ENSMUST00000171263.8
ENSMUST00000045097.11
guanylate binding protein 7
chr8_-_112064783 0.79 ENSMUST00000056157.14
ENSMUST00000120432.3
mixed lineage kinase domain-like
chr8_+_71261073 0.78 ENSMUST00000000808.8
ENSMUST00000212657.2
ENSMUST00000212146.2
interleukin 12 receptor, beta 1
chr9_+_20779924 0.77 ENSMUST00000043911.8
shiftless antiviral inhibitor of ribosomal frameshifting
chr16_+_23428650 0.76 ENSMUST00000038423.6
ENSMUST00000211349.2
receptor transporter protein 4
chr9_+_107852733 0.75 ENSMUST00000035216.11
ubiquitin-like modifier activating enzyme 7
chr3_+_142202642 0.73 ENSMUST00000090127.7
guanylate binding protein 5
chr16_+_35758836 0.71 ENSMUST00000114878.8
poly (ADP-ribose) polymerase family, member 9
chr13_-_23894697 0.69 ENSMUST00000091707.13
ENSMUST00000006787.8
homeostatic iron regulator
chr5_-_105287405 0.67 ENSMUST00000100961.5
ENSMUST00000031235.13
ENSMUST00000197799.2
ENSMUST00000199629.2
ENSMUST00000196677.5
ENSMUST00000100962.8
guanylate-binding protein 9
guanylate-binding protein 8
guanylate binding protein 4
chr3_+_68598757 0.67 ENSMUST00000107816.4
interleukin 12a
chr10_-_34003933 0.67 ENSMUST00000062784.8
calcium homeostasis modulator family member 6
chr5_-_120887864 0.66 ENSMUST00000053909.13
ENSMUST00000081491.13
2'-5' oligoadenylate synthetase 2
chr17_+_34406762 0.64 ENSMUST00000041633.15
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr6_-_34294377 0.64 ENSMUST00000154655.2
ENSMUST00000102980.11
aldo-keto reductase family 1, member B3 (aldose reductase)
chr6_+_40619913 0.63 ENSMUST00000238599.2
maltase-glucoamylase
chr4_-_40239700 0.62 ENSMUST00000142055.2
DEAD/H box helicase 58
chr6_-_39095144 0.62 ENSMUST00000038398.7
poly (ADP-ribose) polymerase family, member 12
chr15_-_98626002 0.61 ENSMUST00000003445.8
FK506 binding protein 11
chr11_+_83066009 0.60 ENSMUST00000000208.13
ENSMUST00000167596.2
schlafen 4
chr17_+_34406523 0.59 ENSMUST00000170086.8
transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)
chr5_+_117495337 0.59 ENSMUST00000031309.16
WD repeat and SOCS box-containing 2
chrX_-_94488394 0.58 ENSMUST00000084535.6
APC membrane recruitment 1
chr2_+_30331839 0.58 ENSMUST00000131476.8
protein phosphatase 2 protein activator
chr1_-_156501860 0.54 ENSMUST00000188964.7
ENSMUST00000190607.2
ENSMUST00000079625.11
torsin family 3, member A
chr5_+_115034997 0.53 ENSMUST00000031542.13
ENSMUST00000146072.8
ENSMUST00000150361.2
2'-5' oligoadenylate synthetase-like 2
chr17_+_29879569 0.53 ENSMUST00000024816.13
ENSMUST00000235031.2
ENSMUST00000234911.2
cap methyltransferase 1
chr2_-_51862941 0.52 ENSMUST00000145481.8
ENSMUST00000112705.9
N-myc (and STAT) interactor
chr1_+_153627692 0.52 ENSMUST00000183241.8
ribonuclease L (2', 5'-oligoisoadenylate synthetase-dependent)
chr16_-_10603389 0.51 ENSMUST00000229866.2
ENSMUST00000038099.6
suppressor of cytokine signaling 1
chr6_-_125208738 0.51 ENSMUST00000043422.8
TAP binding protein-like
chr6_+_145067457 0.50 ENSMUST00000032396.13
lymphoid-restricted membrane protein
chr8_+_95161006 0.50 ENSMUST00000211816.2
NLR family, CARD domain containing 5
chr8_+_80366247 0.49 ENSMUST00000173078.8
ENSMUST00000173286.8
OTU domain containing 4
chr16_-_22946441 0.49 ENSMUST00000133847.9
ENSMUST00000115338.8
ENSMUST00000023598.15
replication factor C (activator 1) 4
chr2_-_25436884 0.48 ENSMUST00000114234.2
TNF receptor-associated factor 2
chr1_+_52158721 0.48 ENSMUST00000186057.7
signal transducer and activator of transcription 1
chr13_-_113237505 0.48 ENSMUST00000224282.2
ENSMUST00000023897.7
granzyme A
chr11_+_29668563 0.47 ENSMUST00000060992.6
reticulon 4
chr11_-_100595019 0.47 ENSMUST00000017974.13
DEXH (Asp-Glu-X-His) box polypeptide 58
chr9_-_14292453 0.47 ENSMUST00000167549.2
endonuclease domain containing 1
chr17_-_34218301 0.46 ENSMUST00000235463.2
histocompatibility 2, K1, K region
chr1_-_37575313 0.45 ENSMUST00000042161.15
mannoside acetylglucosaminyltransferase 4, isoenzyme A
chr7_-_102214636 0.45 ENSMUST00000106913.3
ENSMUST00000033264.12
tripartite motif-containing 21
chr17_-_35081129 0.45 ENSMUST00000154526.8
complement factor B
chr7_-_144493560 0.44 ENSMUST00000093962.5
cyclin D1
chr7_-_44785603 0.44 ENSMUST00000209467.2
predicted gene 45713
chr12_-_79054050 0.44 ENSMUST00000056660.13
ENSMUST00000174721.8
transmembrane protein 229B
chr4_-_156285247 0.44 ENSMUST00000085425.6
ISG15 ubiquitin-like modifier
chr11_-_48817986 0.44 ENSMUST00000094476.9
predicted gene 12185
chr17_+_29879684 0.44 ENSMUST00000235014.2
ENSMUST00000130423.4
cap methyltransferase 1
chr11_+_72192455 0.44 ENSMUST00000151440.8
ENSMUST00000146233.8
ENSMUST00000140842.9
XIAP associated factor 1
chr8_-_112064393 0.44 ENSMUST00000145862.3
mixed lineage kinase domain-like
chr13_+_34346936 0.44 ENSMUST00000124996.8
ENSMUST00000147632.3
proteasome (prosome, macropain) assembly chaperone 4
chr17_+_6869070 0.43 ENSMUST00000092966.5
dynein light chain Tctex-type 1C
chr19_-_3955230 0.43 ENSMUST00000145791.8
T cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 protein A3
chr15_+_75734159 0.43 ENSMUST00000023238.6
ENSMUST00000230514.2
ENSMUST00000229331.2
gasdermin D
chr3_-_50398027 0.43 ENSMUST00000029297.6
ENSMUST00000194462.6
solute carrier family 7 (cationic amino acid transporter, y+ system), member 11
chr13_-_30170031 0.43 ENSMUST00000102948.11
E2F transcription factor 3
chr1_-_173859321 0.42 ENSMUST00000059226.7
interferon activated gene 205
chr5_-_105258142 0.41 ENSMUST00000031238.13
guanylate-binding protein 9
chr19_+_36387123 0.41 ENSMUST00000225411.2
ENSMUST00000062389.6
polycomb group ring finger 5
chr1_+_52158599 0.41 ENSMUST00000186574.7
ENSMUST00000070968.14
ENSMUST00000191435.7
ENSMUST00000186857.7
ENSMUST00000188681.7
signal transducer and activator of transcription 1
chr19_-_44134872 0.40 ENSMUST00000237630.2
ENSMUST00000079033.6
biogenesis of lysosomal organelles complex-1, subunit 2
chr17_+_29251602 0.40 ENSMUST00000130216.3
serine and arginine-rich splicing factor 3
chr12_+_26519203 0.40 ENSMUST00000020969.5
cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial
chr18_-_43610829 0.40 ENSMUST00000057110.11
eukaryotic translation initiation factor 3, subunit J2
chr12_+_71021395 0.40 ENSMUST00000160027.8
ENSMUST00000160864.8
proteasome subunit alpha 3
chr14_-_78970160 0.40 ENSMUST00000226342.3
diacylglycerol kinase, eta
chr2_-_132095146 0.40 ENSMUST00000028817.7
proliferating cell nuclear antigen
chr8_-_79547707 0.40 ENSMUST00000130325.8
ENSMUST00000051867.7
LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated
chr12_-_80307110 0.39 ENSMUST00000021554.16
actinin, alpha 1
chr2_-_25436952 0.39 ENSMUST00000028311.13
TNF receptor-associated factor 2
chr9_+_5298669 0.38 ENSMUST00000238505.2
caspase 1
chr11_-_118292678 0.38 ENSMUST00000106290.4
lectin, galactoside-binding, soluble, 3 binding protein
chr7_+_138828391 0.38 ENSMUST00000093993.5
ENSMUST00000172136.9
PWWP domain containing 2B
chr17_+_35643818 0.38 ENSMUST00000174699.8
histocompatibility 2, Q region locus 6
chr3_+_94350622 0.38 ENSMUST00000029786.14
ENSMUST00000196143.2
mitochondrial ribosomal protein L9
chr17_+_35598583 0.37 ENSMUST00000081435.5
histocompatibility 2, Q region locus 4
chr19_+_45549009 0.37 ENSMUST00000047057.9
predicted gene 17018
chr8_+_79236051 0.37 ENSMUST00000209992.2
solute carrier family 10 (sodium/bile acid cotransporter family), member 7
chr1_+_175459559 0.36 ENSMUST00000040250.15
kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
chr15_+_74593041 0.36 ENSMUST00000070923.3
thioesterase superfamily member 6
chr1_+_52158693 0.36 ENSMUST00000189347.7
signal transducer and activator of transcription 1
chr3_-_94794256 0.36 ENSMUST00000005923.7
proteasome (prosome, macropain) subunit, beta type 4
chr11_+_101339233 0.36 ENSMUST00000010502.13
interferon-induced protein 35
chr17_-_34219225 0.36 ENSMUST00000238098.2
ENSMUST00000087189.7
ENSMUST00000173075.3
ENSMUST00000172912.8
ENSMUST00000236740.2
ENSMUST00000025181.18
histocompatibility 2, K1, K region
chr11_+_29080733 0.36 ENSMUST00000020756.9
polyribonucleotide nucleotidyltransferase 1
chr18_+_60345152 0.35 ENSMUST00000031549.6
predicted gene 4951
chr11_+_48977495 0.35 ENSMUST00000152914.2
interferon gamma inducible protein 47
chr3_-_107667499 0.35 ENSMUST00000153114.2
ENSMUST00000118593.8
ENSMUST00000120243.8
colony stimulating factor 1 (macrophage)
chr11_+_58090382 0.35 ENSMUST00000035266.11
ENSMUST00000094169.11
ENSMUST00000168280.2
ENSMUST00000058704.9
interferon gamma induced GTPase
immunity-related GTPase family M member 2
chr10_-_94780695 0.34 ENSMUST00000099337.5
plexin C1
chr17_+_35643853 0.34 ENSMUST00000113879.4
histocompatibility 2, Q region locus 6
chr3_-_104725853 0.33 ENSMUST00000106775.8
ENSMUST00000166979.8
Mov10 RISC complex RNA helicase
chr17_+_35780977 0.33 ENSMUST00000174525.8
ENSMUST00000068291.7
histocompatibility 2, Q region locus 10
chr12_-_108859123 0.32 ENSMUST00000161154.2
ENSMUST00000161410.8
tryptophanyl-tRNA synthetase
chr7_+_103893658 0.32 ENSMUST00000106849.9
ENSMUST00000060315.12
tripartite motif-containing 34A
chr5_-_105387395 0.32 ENSMUST00000065588.7
guanylate-binding protein 10
chr3_-_104725581 0.32 ENSMUST00000168015.8
Mov10 RISC complex RNA helicase
chr17_-_35081456 0.32 ENSMUST00000025229.11
ENSMUST00000176203.9
ENSMUST00000128767.8
complement factor B
chr2_-_155668567 0.31 ENSMUST00000109638.2
ENSMUST00000134278.2
eukaryotic translation initiation factor 6
chr14_-_55828511 0.31 ENSMUST00000161807.8
ENSMUST00000111378.10
ENSMUST00000159687.2
proteasome (prosome, macropain) activator subunit 2 (PA28 beta)
chr11_+_69737491 0.31 ENSMUST00000019605.4
phospholipid scramblase 3
chr16_-_92196954 0.31 ENSMUST00000023672.10
regulator of calcineurin 1
chr18_+_60509101 0.30 ENSMUST00000032473.7
ENSMUST00000066912.13
interferon inducible GTPase 1
chr14_+_55815999 0.30 ENSMUST00000172738.2
ENSMUST00000089619.13
proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
chr13_+_120761861 0.30 ENSMUST00000225029.2
cDNA sequence BC147527
chr17_-_6923299 0.30 ENSMUST00000179554.3
dynein light chain Tctex-type 1F
chr8_-_106665060 0.30 ENSMUST00000034369.10
proteasome (prosome, macropain) subunit, beta type 10
chr18_+_60907698 0.29 ENSMUST00000118551.8
ribosomal protein S14
chr7_-_44888465 0.29 ENSMUST00000210078.2
CD37 antigen
chr2_-_65955338 0.29 ENSMUST00000028378.4
polypeptide N-acetylgalactosaminyltransferase 3
chr1_-_173770010 0.29 ENSMUST00000042228.15
ENSMUST00000081216.12
ENSMUST00000129829.8
ENSMUST00000123708.8
interferon activated gene 203
chr7_-_112946481 0.28 ENSMUST00000117577.8
BTB (POZ) domain containing 10
chr7_-_144837719 0.28 ENSMUST00000058022.6
two pore segment channel 2
chr17_+_6697511 0.28 ENSMUST00000179569.3
dynein light chain Tctex-type 1B
chr18_+_58792514 0.28 ENSMUST00000025503.10
ENSMUST00000238139.2
isochorismatase domain containing 1
chr12_-_90705212 0.28 ENSMUST00000082432.6
deiodinase, iodothyronine, type II
chr1_+_85454323 0.28 ENSMUST00000239236.2
predicted gene 7592
chr10_-_88192852 0.27 ENSMUST00000020249.2
DNA-damage regulated autophagy modulator 1
chr19_+_8875459 0.27 ENSMUST00000096246.5
ENSMUST00000235274.2
alpha glucosidase 2 alpha neutral subunit
chr2_+_19376447 0.27 ENSMUST00000023856.9
methionine sulfoxide reductase B2
chr18_+_60907668 0.27 ENSMUST00000025511.11
ribosomal protein S14
chr19_-_8775817 0.27 ENSMUST00000235964.2
polymerase (RNA) II (DNA directed) polypeptide G
chr13_+_33188511 0.27 ENSMUST00000006391.5
serine (or cysteine) peptidase inhibitor, clade B, member 9
chr10_+_39488930 0.26 ENSMUST00000019987.7
TRAF3 interacting protein 2
chr4_+_138700195 0.26 ENSMUST00000123636.8
ENSMUST00000043042.10
ENSMUST00000050949.9
transmembrane and coiled-coil domains 4
chr2_-_51824656 0.26 ENSMUST00000165313.2
RNA binding motif protein 43
chr5_-_120915693 0.26 ENSMUST00000044833.9
2'-5' oligoadenylate synthetase 3
chr1_-_171050004 0.26 ENSMUST00000147246.2
ENSMUST00000111326.8
ENSMUST00000138184.8
translocase of outer mitochondrial membrane 40-like
chr8_+_72943455 0.26 ENSMUST00000072097.14
hematopoietic SH2 domain containing
chr17_+_37581103 0.26 ENSMUST00000038580.7
histocompatibility 2, M region locus 3
chr11_+_48967411 0.26 ENSMUST00000109202.3
interferon gamma inducible protein 47
chr7_+_103893672 0.25 ENSMUST00000106848.8
tripartite motif-containing 34A
chr3_-_104725535 0.25 ENSMUST00000002297.12
Mov10 RISC complex RNA helicase
chr15_-_78947038 0.25 ENSMUST00000151889.8
ENSMUST00000040676.11
ankyrin repeat domain 54
chr16_-_16176390 0.25 ENSMUST00000115749.3
ENSMUST00000230022.2
dynamin 1-like
chr7_-_101667346 0.25 ENSMUST00000209844.2
ENSMUST00000211502.2
ENSMUST00000094134.5
interleukin 18 binding protein
chr5_-_121045568 0.24 ENSMUST00000080322.8
2'-5' oligoadenylate synthetase 1A
chr2_+_22785534 0.24 ENSMUST00000053729.14
prenyl (solanesyl) diphosphate synthase, subunit 1
chr7_+_80510658 0.24 ENSMUST00000132163.8
ENSMUST00000205361.2
ENSMUST00000147125.2
zinc finger and SCAN domain containing 2
chr17_+_34138699 0.24 ENSMUST00000234320.2
TAP binding protein
chr14_+_55815879 0.24 ENSMUST00000174563.8
proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
chr2_+_180231038 0.24 ENSMUST00000029087.4
opioid growth factor receptor
chr7_+_130179063 0.24 ENSMUST00000207918.2
ENSMUST00000215492.2
ENSMUST00000084513.12
ENSMUST00000059145.14
transforming, acidic coiled-coil containing protein 2
chr3_+_27371206 0.24 ENSMUST00000174840.2
tumor necrosis factor (ligand) superfamily, member 10
chr17_+_35481702 0.24 ENSMUST00000172785.8
histocompatibility 2, D region locus 1
chr1_+_155911451 0.23 ENSMUST00000111754.9
torsin A interacting protein 2
chr11_-_35725317 0.23 ENSMUST00000018992.4
arginyl-tRNA synthetase
chr9_-_14956704 0.23 ENSMUST00000164273.9
pannexin 1
chr7_-_130148984 0.23 ENSMUST00000160289.9
NSE4 homolog A, SMC5-SMC6 complex component
chrX_+_10581248 0.23 ENSMUST00000144356.8
Mid1 interacting protein 1 (gastrulation specific G12-like (zebrafish))
chr19_-_8775935 0.22 ENSMUST00000096261.5
polymerase (RNA) II (DNA directed) polypeptide G
chr11_-_69572648 0.22 ENSMUST00000005336.9
SUMO/sentrin specific peptidase 3
chr7_-_84661476 0.22 ENSMUST00000124773.3
ENSMUST00000233725.2
ENSMUST00000233739.2
ENSMUST00000232837.2
vomeronasal 2, receptor 66
chr13_+_52000704 0.21 ENSMUST00000021903.3
growth arrest and DNA-damage-inducible 45 gamma
chr4_+_155666933 0.21 ENSMUST00000105612.2
NAD kinase
chr4_+_106418224 0.21 ENSMUST00000047973.4
24-dehydrocholesterol reductase
chr7_-_117728790 0.21 ENSMUST00000206491.2
ADP-ribosylation factor-like 6 interacting protein 1
chr12_-_79027531 0.21 ENSMUST00000174072.8
transmembrane protein 229B
chr13_-_23894828 0.21 ENSMUST00000091706.14
homeostatic iron regulator
chr7_-_126074222 0.21 ENSMUST00000205497.2
SH2B adaptor protein 1
chr5_-_121025645 0.21 ENSMUST00000086368.12
2'-5' oligoadenylate synthetase 1G
chr5_-_134581235 0.21 ENSMUST00000036999.10
ENSMUST00000100647.7
CAP-GLY domain containing linker protein 2
chr11_+_88890202 0.21 ENSMUST00000100627.9
ENSMUST00000107896.10
ENSMUST00000000284.7
tripartite motif-containing 25
chr14_+_55842002 0.21 ENSMUST00000138037.2
interferon regulatory factor 9
chr5_+_115061293 0.21 ENSMUST00000031540.11
ENSMUST00000112143.4
2'-5' oligoadenylate synthetase-like 1
chr7_-_104157006 0.21 ENSMUST00000033211.14
ENSMUST00000071069.13
tripartite motif-containing 30D
chr18_-_67378886 0.20 ENSMUST00000073054.5
metallophosphoesterase 1
chr7_-_126194097 0.20 ENSMUST00000058429.6
interleukin 27
chr16_-_56984137 0.20 ENSMUST00000231733.2
nitrilase family, member 2

Network of associatons between targets according to the STRING database.

First level regulatory network of Irf2_Irf1_Irf8_Irf9_Irf7

PNG image of the network

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Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.6 1.7 GO:1902524 positive regulation of protein K48-linked ubiquitination(GO:1902524)
0.5 1.4 GO:0002590 negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590)
0.4 1.3 GO:0046967 cytosol to ER transport(GO:0046967)
0.4 0.4 GO:0051673 membrane disruption in other organism(GO:0051673)
0.4 1.3 GO:0034240 negative regulation of macrophage fusion(GO:0034240)
0.3 9.4 GO:0044406 adhesion of symbiont to host(GO:0044406)
0.3 1.7 GO:0009597 detection of virus(GO:0009597)
0.3 2.1 GO:0060335 positive regulation of response to interferon-gamma(GO:0060332) positive regulation of interferon-gamma-mediated signaling pathway(GO:0060335)
0.3 1.7 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.3 1.1 GO:0070212 protein poly-ADP-ribosylation(GO:0070212)
0.3 1.1 GO:1901740 negative regulation of myoblast fusion(GO:1901740)
0.3 1.1 GO:0002484 antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway(GO:0002484) antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent(GO:0002485)
0.2 0.9 GO:0098795 mRNA cleavage involved in gene silencing by miRNA(GO:0035279) mRNA cleavage involved in gene silencing(GO:0098795)
0.2 0.4 GO:1903969 regulation of macrophage colony-stimulating factor signaling pathway(GO:1902226) regulation of response to macrophage colony-stimulating factor(GO:1903969) regulation of cellular response to macrophage colony-stimulating factor stimulus(GO:1903972)
0.2 1.1 GO:0097309 cap1 mRNA methylation(GO:0097309)
0.2 0.6 GO:0090420 hexitol metabolic process(GO:0006059) naphthalene metabolic process(GO:0018931) naphthalene-containing compound metabolic process(GO:0090420)
0.2 2.1 GO:0060330 regulation of response to interferon-gamma(GO:0060330)
0.2 0.4 GO:0002476 antigen processing and presentation of endogenous peptide antigen via MHC class Ib(GO:0002476)
0.2 0.6 GO:0030472 mitotic spindle organization in nucleus(GO:0030472)
0.2 1.3 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.2 1.3 GO:1903265 positive regulation of tumor necrosis factor-mediated signaling pathway(GO:1903265)
0.2 7.8 GO:0035458 cellular response to interferon-beta(GO:0035458)
0.2 0.8 GO:0072734 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.1 0.4 GO:0006233 dTDP biosynthetic process(GO:0006233) dTDP metabolic process(GO:0046072)
0.1 0.1 GO:0046725 negative regulation by virus of viral protein levels in host cell(GO:0046725)
0.1 0.3 GO:1902626 assembly of large subunit precursor of preribosome(GO:1902626)
0.1 0.4 GO:1902990 leading strand elongation(GO:0006272) mitotic telomere maintenance via semi-conservative replication(GO:1902990)
0.1 0.8 GO:0071787 endoplasmic reticulum tubular network assembly(GO:0071787)
0.1 0.3 GO:1900063 mitochondrial membrane fission(GO:0090149) regulation of peroxisome organization(GO:1900063)
0.1 0.7 GO:2000510 positive regulation of dendritic cell chemotaxis(GO:2000510)
0.1 0.7 GO:0018377 protein myristoylation(GO:0018377)
0.1 0.3 GO:0006436 tryptophanyl-tRNA aminoacylation(GO:0006436)
0.1 0.2 GO:0050717 positive regulation of interleukin-1 alpha secretion(GO:0050717)
0.1 0.8 GO:2000051 negative regulation of non-canonical Wnt signaling pathway(GO:2000051)
0.1 0.7 GO:1900227 positive regulation of NLRP3 inflammasome complex assembly(GO:1900227)
0.1 0.1 GO:0006235 dTTP biosynthetic process(GO:0006235) pyrimidine deoxyribonucleoside triphosphate biosynthetic process(GO:0009212) dTTP metabolic process(GO:0046075)
0.1 2.0 GO:0000028 ribosomal small subunit assembly(GO:0000028)
0.1 0.2 GO:0002276 basophil activation involved in immune response(GO:0002276)
0.1 0.3 GO:0070460 thyroid-stimulating hormone secretion(GO:0070460)
0.1 0.3 GO:0030091 protein repair(GO:0030091)
0.1 0.7 GO:0032071 regulation of endodeoxyribonuclease activity(GO:0032071)
0.1 0.6 GO:1900264 regulation of DNA-directed DNA polymerase activity(GO:1900262) positive regulation of DNA-directed DNA polymerase activity(GO:1900264)
0.1 0.2 GO:0036367 adaptation of rhodopsin mediated signaling(GO:0016062) light adaption(GO:0036367)
0.1 0.1 GO:0010899 regulation of phosphatidylcholine catabolic process(GO:0010899)
0.1 0.1 GO:0009138 dUDP biosynthetic process(GO:0006227) pyrimidine nucleoside diphosphate metabolic process(GO:0009138) pyrimidine nucleoside diphosphate biosynthetic process(GO:0009139) pyrimidine deoxyribonucleoside diphosphate metabolic process(GO:0009196) pyrimidine deoxyribonucleoside diphosphate biosynthetic process(GO:0009197) dUDP metabolic process(GO:0046077)
0.1 0.2 GO:0030887 positive regulation of myeloid dendritic cell activation(GO:0030887)
0.1 0.2 GO:0034165 positive regulation of toll-like receptor 9 signaling pathway(GO:0034165)
0.1 0.6 GO:0072161 mesenchymal cell differentiation involved in kidney development(GO:0072161) mesenchymal cell differentiation involved in renal system development(GO:2001012)
0.1 0.5 GO:0070141 response to UV-A(GO:0070141)
0.1 0.1 GO:2000508 regulation of dendritic cell chemotaxis(GO:2000508)
0.1 0.2 GO:0090367 negative regulation of mRNA modification(GO:0090367)
0.1 0.1 GO:0006404 RNA import into nucleus(GO:0006404)
0.1 0.3 GO:0090669 snoRNA guided rRNA pseudouridine synthesis(GO:0000454) telomerase RNA stabilization(GO:0090669)
0.1 0.1 GO:0035928 rRNA import into mitochondrion(GO:0035928)
0.1 2.1 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.1 0.4 GO:0060700 regulation of ribonuclease activity(GO:0060700)
0.1 0.3 GO:0038128 ERBB2 signaling pathway(GO:0038128)
0.0 0.1 GO:0019883 antigen processing and presentation of endogenous antigen(GO:0019883)
0.0 0.3 GO:0018242 protein O-linked glycosylation via serine(GO:0018242)
0.0 0.1 GO:0006393 termination of mitochondrial transcription(GO:0006393)
0.0 0.4 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.0 0.2 GO:0006420 arginyl-tRNA aminoacylation(GO:0006420)
0.0 0.1 GO:1900369 negative regulation of RNA interference(GO:1900369)
0.0 1.1 GO:0097066 response to thyroid hormone(GO:0097066)
0.0 0.3 GO:0051902 negative regulation of mitochondrial depolarization(GO:0051902)
0.0 0.1 GO:0019255 UDP-glucose metabolic process(GO:0006011) glucose 1-phosphate metabolic process(GO:0019255)
0.0 0.4 GO:0015712 hexose phosphate transport(GO:0015712) glucose-6-phosphate transport(GO:0015760)
0.0 0.2 GO:0034499 late endosome to Golgi transport(GO:0034499)
0.0 0.2 GO:0001732 formation of cytoplasmic translation initiation complex(GO:0001732)
0.0 0.1 GO:1902071 regulation of hypoxia-inducible factor-1alpha signaling pathway(GO:1902071)
0.0 0.4 GO:0089711 L-glutamate transmembrane transport(GO:0089711)
0.0 1.0 GO:0035634 response to stilbenoid(GO:0035634)
0.0 0.4 GO:0007039 protein catabolic process in the vacuole(GO:0007039)
0.0 0.2 GO:0002606 positive regulation of dendritic cell antigen processing and presentation(GO:0002606)
0.0 0.1 GO:0042270 protection from natural killer cell mediated cytotoxicity(GO:0042270)
0.0 0.2 GO:0010991 regulation of SMAD protein complex assembly(GO:0010990) negative regulation of SMAD protein complex assembly(GO:0010991)
0.0 0.2 GO:0006041 glucosamine metabolic process(GO:0006041) UDP-N-acetylglucosamine biosynthetic process(GO:0006048)
0.0 0.3 GO:1900225 regulation of NLRP3 inflammasome complex assembly(GO:1900225)
0.0 0.0 GO:1990009 retinal cell apoptotic process(GO:1990009)
0.0 0.2 GO:1901297 positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment(GO:1901297) positive regulation of canonical Wnt signaling pathway involved in heart development(GO:1905068)
0.0 0.5 GO:0043248 proteasome assembly(GO:0043248)
0.0 0.1 GO:0097048 dendritic cell apoptotic process(GO:0097048) regulation of dendritic cell apoptotic process(GO:2000668)
0.0 0.4 GO:0090086 negative regulation of protein deubiquitination(GO:0090086)
0.0 0.1 GO:0050705 regulation of interleukin-1 alpha secretion(GO:0050705)
0.0 0.1 GO:0061428 negative regulation of transcription from RNA polymerase II promoter in response to hypoxia(GO:0061428)
0.0 0.2 GO:0060523 prostate epithelial cord elongation(GO:0060523)
0.0 0.2 GO:0070885 negative regulation of calcineurin-NFAT signaling cascade(GO:0070885)
0.0 0.2 GO:0006189 'de novo' IMP biosynthetic process(GO:0006189)
0.0 0.2 GO:0006543 glutamate biosynthetic process(GO:0006537) glutamine catabolic process(GO:0006543)
0.0 0.1 GO:0042262 DNA protection(GO:0042262)
0.0 0.2 GO:0034975 protein folding in endoplasmic reticulum(GO:0034975)
0.0 0.3 GO:0090230 regulation of centromere complex assembly(GO:0090230)
0.0 1.5 GO:0070207 protein homotrimerization(GO:0070207)
0.0 0.2 GO:0019805 quinolinate biosynthetic process(GO:0019805)
0.0 0.2 GO:2000562 negative regulation of CD4-positive, alpha-beta T cell proliferation(GO:2000562)
0.0 0.5 GO:0002230 positive regulation of defense response to virus by host(GO:0002230)
0.0 0.1 GO:0007089 traversing start control point of mitotic cell cycle(GO:0007089)
0.0 0.1 GO:0002884 negative regulation of hypersensitivity(GO:0002884)
0.0 1.4 GO:0046825 regulation of protein export from nucleus(GO:0046825)
0.0 0.1 GO:0055005 ventricular cardiac myofibril assembly(GO:0055005)
0.0 0.1 GO:0070947 neutrophil mediated killing of fungus(GO:0070947)
0.0 0.4 GO:0002862 negative regulation of inflammatory response to antigenic stimulus(GO:0002862)
0.0 0.1 GO:1903976 negative regulation of glial cell migration(GO:1903976)
0.0 0.1 GO:0097343 ripoptosome assembly(GO:0097343) ripoptosome assembly involved in necroptotic process(GO:1901026)
0.0 0.2 GO:0019856 'de novo' pyrimidine nucleobase biosynthetic process(GO:0006207) pyrimidine nucleobase biosynthetic process(GO:0019856)
0.0 0.5 GO:0046473 phosphatidic acid metabolic process(GO:0046473)
0.0 0.1 GO:0051754 meiotic sister chromatid cohesion, centromeric(GO:0051754)
0.0 0.6 GO:2001275 positive regulation of glucose import in response to insulin stimulus(GO:2001275)
0.0 0.5 GO:0000291 nuclear-transcribed mRNA catabolic process, exonucleolytic(GO:0000291)
0.0 0.6 GO:0019884 antigen processing and presentation of exogenous antigen(GO:0019884)
0.0 0.1 GO:0036275 response to 5-fluorouracil(GO:0036275)
0.0 0.4 GO:0030150 protein import into mitochondrial matrix(GO:0030150)
0.0 0.6 GO:0051205 protein insertion into membrane(GO:0051205)
0.0 1.0 GO:0090200 positive regulation of release of cytochrome c from mitochondria(GO:0090200)
0.0 0.1 GO:0019853 L-ascorbic acid biosynthetic process(GO:0019853)
0.0 0.1 GO:0045918 negative regulation of cytolysis(GO:0045918)
0.0 0.2 GO:0006741 NADP biosynthetic process(GO:0006741)
0.0 0.1 GO:0070843 misfolded protein transport(GO:0070843) polyubiquitinated protein transport(GO:0070844) polyubiquitinated misfolded protein transport(GO:0070845) Hsp90 deacetylation(GO:0070846)
0.0 0.1 GO:0006438 valyl-tRNA aminoacylation(GO:0006438)
0.0 0.0 GO:1903538 meiotic cell cycle process involved in oocyte maturation(GO:1903537) regulation of meiotic cell cycle process involved in oocyte maturation(GO:1903538)
0.0 0.9 GO:0019882 antigen processing and presentation(GO:0019882)
0.0 0.2 GO:0006528 asparagine metabolic process(GO:0006528)
0.0 0.1 GO:0016240 autophagosome docking(GO:0016240)
0.0 0.2 GO:0090074 negative regulation of protein homodimerization activity(GO:0090074)
0.0 0.1 GO:2000371 phosphatidylserine biosynthetic process(GO:0006659) regulation of isomerase activity(GO:0010911) positive regulation of isomerase activity(GO:0010912) regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000371) positive regulation of DNA topoisomerase (ATP-hydrolyzing) activity(GO:2000373)
0.0 0.2 GO:0052805 imidazole-containing compound catabolic process(GO:0052805)
0.0 0.1 GO:0061511 centriole elongation(GO:0061511)
0.0 0.1 GO:0032747 positive regulation of interleukin-23 production(GO:0032747)
0.0 0.2 GO:0048102 autophagic cell death(GO:0048102)
0.0 0.1 GO:2001245 negative regulation of phospholipid biosynthetic process(GO:0071072) regulation of phosphatidylcholine biosynthetic process(GO:2001245)
0.0 0.1 GO:0051534 negative regulation of NFAT protein import into nucleus(GO:0051534)
0.0 0.1 GO:0072602 interleukin-4 secretion(GO:0072602)
0.0 0.1 GO:0045726 positive regulation of integrin biosynthetic process(GO:0045726) oxygen metabolic process(GO:0072592)
0.0 0.1 GO:2000676 positive regulation of type B pancreatic cell apoptotic process(GO:2000676)
0.0 0.2 GO:0060763 mammary duct terminal end bud growth(GO:0060763)
0.0 0.5 GO:0097345 mitochondrial outer membrane permeabilization(GO:0097345)
0.0 0.1 GO:0034421 post-translational protein acetylation(GO:0034421)
0.0 0.1 GO:2000348 regulation of CD40 signaling pathway(GO:2000348)
0.0 0.1 GO:0060837 blood vessel endothelial cell differentiation(GO:0060837)
0.0 0.1 GO:2000397 regulation of ubiquitin-dependent endocytosis(GO:2000395) positive regulation of ubiquitin-dependent endocytosis(GO:2000397)
0.0 0.2 GO:0044351 macropinocytosis(GO:0044351)
0.0 0.1 GO:0090666 scaRNA localization to Cajal body(GO:0090666)
0.0 0.1 GO:0033082 regulation of extrathymic T cell differentiation(GO:0033082)
0.0 0.5 GO:0071108 protein K48-linked deubiquitination(GO:0071108)
0.0 0.1 GO:2000659 regulation of interleukin-1-mediated signaling pathway(GO:2000659)
0.0 0.1 GO:0010940 positive regulation of necrotic cell death(GO:0010940)
0.0 0.1 GO:1904629 negative regulation of interleukin-12 biosynthetic process(GO:0045083) response to diterpene(GO:1904629) cellular response to diterpene(GO:1904630) response to glucoside(GO:1904631) cellular response to glucoside(GO:1904632)
0.0 0.1 GO:0042776 mitochondrial ATP synthesis coupled proton transport(GO:0042776)
0.0 0.2 GO:1901970 positive regulation of mitotic metaphase/anaphase transition(GO:0045842) positive regulation of mitotic sister chromatid separation(GO:1901970) positive regulation of metaphase/anaphase transition of cell cycle(GO:1902101)
0.0 0.1 GO:0007290 spermatid nucleus elongation(GO:0007290)
0.0 0.1 GO:0003199 endocardial cushion to mesenchymal transition involved in heart valve formation(GO:0003199)
0.0 0.1 GO:0039530 MDA-5 signaling pathway(GO:0039530)
0.0 0.0 GO:0036500 ATF6-mediated unfolded protein response(GO:0036500)
0.0 0.0 GO:0061193 taste bud development(GO:0061193)
0.0 0.0 GO:0046351 disaccharide biosynthetic process(GO:0046351)
0.0 0.4 GO:0008053 mitochondrial fusion(GO:0008053)
0.0 0.2 GO:0000185 activation of MAPKKK activity(GO:0000185)
0.0 0.4 GO:0006744 ubiquinone biosynthetic process(GO:0006744)
0.0 0.4 GO:0051639 actin filament network formation(GO:0051639)
0.0 0.1 GO:0032379 positive regulation of intracellular lipid transport(GO:0032379) positive regulation of intracellular sterol transport(GO:0032382) positive regulation of intracellular cholesterol transport(GO:0032385) lipid hydroperoxide transport(GO:1901373)
0.0 0.1 GO:0046784 viral mRNA export from host cell nucleus(GO:0046784)
0.0 0.0 GO:0009107 lipoate biosynthetic process(GO:0009107)
0.0 0.3 GO:0031987 locomotion involved in locomotory behavior(GO:0031987)
0.0 0.1 GO:0072355 histone H3-T3 phosphorylation(GO:0072355)
0.0 0.1 GO:1903690 negative regulation of wound healing, spreading of epidermal cells(GO:1903690)
0.0 0.2 GO:0010606 positive regulation of cytoplasmic mRNA processing body assembly(GO:0010606)
0.0 0.1 GO:0060762 regulation of branching involved in mammary gland duct morphogenesis(GO:0060762)
0.0 0.0 GO:1904959 regulation of cytochrome-c oxidase activity(GO:1904959)
0.0 0.2 GO:0001682 tRNA 5'-leader removal(GO:0001682)
0.0 0.1 GO:0030886 negative regulation of myeloid dendritic cell activation(GO:0030886)
0.0 0.0 GO:0038156 interleukin-3-mediated signaling pathway(GO:0038156)
0.0 0.1 GO:0042758 long-chain fatty acid catabolic process(GO:0042758)
0.0 0.1 GO:0098909 regulation of cardiac muscle cell action potential involved in regulation of contraction(GO:0098909)
0.0 0.1 GO:0001731 formation of translation preinitiation complex(GO:0001731)
0.0 0.1 GO:0006547 histidine biosynthetic process(GO:0000105) histidine metabolic process(GO:0006547)
0.0 0.1 GO:2001166 regulation of histone H2B ubiquitination(GO:2001166) positive regulation of histone H2B ubiquitination(GO:2001168)
0.0 0.2 GO:0090336 positive regulation of brown fat cell differentiation(GO:0090336)
0.0 0.1 GO:0090521 glomerular visceral epithelial cell migration(GO:0090521)
0.0 0.2 GO:0015838 amino-acid betaine transport(GO:0015838)
0.0 0.1 GO:0006335 DNA replication-dependent nucleosome assembly(GO:0006335) DNA replication-dependent nucleosome organization(GO:0034723)
0.0 0.1 GO:0006450 regulation of translational fidelity(GO:0006450)
0.0 0.2 GO:0006388 tRNA splicing, via endonucleolytic cleavage and ligation(GO:0006388)
0.0 0.1 GO:0045654 positive regulation of megakaryocyte differentiation(GO:0045654)
0.0 0.1 GO:0002741 positive regulation of cytokine secretion involved in immune response(GO:0002741)
0.0 0.0 GO:0036090 cleavage furrow ingression(GO:0036090)
0.0 0.1 GO:0034058 endosomal vesicle fusion(GO:0034058)
0.0 0.2 GO:0031507 heterochromatin assembly(GO:0031507)
0.0 0.1 GO:0032790 ribosome disassembly(GO:0032790)
0.0 0.1 GO:0046501 protoporphyrinogen IX metabolic process(GO:0046501)
0.0 0.0 GO:0042128 nitrate assimilation(GO:0042128)
0.0 0.0 GO:0006669 sphinganine-1-phosphate biosynthetic process(GO:0006669)
0.0 0.2 GO:0000054 ribosomal subunit export from nucleus(GO:0000054) ribosome localization(GO:0033750) establishment of ribosome localization(GO:0033753)
0.0 0.1 GO:0019262 N-acetylneuraminate catabolic process(GO:0019262)
0.0 0.3 GO:0016578 histone deubiquitination(GO:0016578)
0.0 0.0 GO:0002314 germinal center B cell differentiation(GO:0002314)
0.0 0.1 GO:1903599 positive regulation of mitophagy(GO:1903599)
0.0 0.2 GO:0016926 protein desumoylation(GO:0016926)
0.0 0.0 GO:1902202 regulation of hepatocyte growth factor receptor signaling pathway(GO:1902202)
0.0 0.1 GO:0042541 hemoglobin biosynthetic process(GO:0042541)
0.0 0.1 GO:0006390 transcription from mitochondrial promoter(GO:0006390)
0.0 0.2 GO:0048280 vesicle fusion with Golgi apparatus(GO:0048280)
0.0 0.1 GO:0045085 negative regulation of interleukin-2 biosynthetic process(GO:0045085)
0.0 0.0 GO:0048698 negative regulation of collateral sprouting in absence of injury(GO:0048698)
0.0 0.3 GO:0022027 interkinetic nuclear migration(GO:0022027)
0.0 0.1 GO:2000774 positive regulation of cellular senescence(GO:2000774)
0.0 0.1 GO:0099639 neurotransmitter receptor transport, endosome to postsynaptic membrane(GO:0098887) endosome to plasma membrane protein transport(GO:0099638) neurotransmitter receptor transport, endosome to plasma membrane(GO:0099639)
0.0 0.0 GO:0060809 CD8-positive, alpha-beta T cell differentiation involved in immune response(GO:0002302) mesodermal to mesenchymal transition involved in gastrulation(GO:0060809)
0.0 0.0 GO:2001200 positive regulation of dendritic cell differentiation(GO:2001200)
0.0 0.1 GO:0003406 retinal pigment epithelium development(GO:0003406)
0.0 0.1 GO:0015676 vanadium ion transport(GO:0015676) lead ion transport(GO:0015692)
0.0 0.1 GO:0042769 DNA damage response, detection of DNA damage(GO:0042769)
0.0 0.2 GO:0034497 protein localization to pre-autophagosomal structure(GO:0034497)
0.0 0.0 GO:0045590 negative regulation of regulatory T cell differentiation(GO:0045590)
0.0 0.1 GO:0036158 outer dynein arm assembly(GO:0036158)
0.0 0.0 GO:1904565 response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904565) cellular response to 1-oleoyl-sn-glycerol 3-phosphate(GO:1904566)
0.0 0.1 GO:0097475 motor neuron migration(GO:0097475)
0.0 0.3 GO:0045648 positive regulation of erythrocyte differentiation(GO:0045648)
0.0 0.0 GO:0000957 mitochondrial RNA catabolic process(GO:0000957) regulation of mitochondrial RNA catabolic process(GO:0000960)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.7 9.9 GO:0020005 symbiont-containing vacuole membrane(GO:0020005)
0.3 1.6 GO:1990111 spermatoproteasome complex(GO:1990111)
0.2 1.5 GO:0042825 TAP complex(GO:0042825)
0.2 0.4 GO:0020003 symbiont-containing vacuole(GO:0020003)
0.2 0.9 GO:0097057 TRAF2-GSTP1 complex(GO:0097057)
0.2 2.2 GO:0042612 MHC class I protein complex(GO:0042612)
0.1 0.6 GO:0097169 AIM2 inflammasome complex(GO:0097169)
0.1 0.4 GO:0070557 PCNA-p21 complex(GO:0070557)
0.1 0.4 GO:0032127 dense core granule membrane(GO:0032127)
0.1 0.6 GO:0097454 Schwann cell microvillus(GO:0097454)
0.1 0.9 GO:1990357 terminal web(GO:1990357)
0.1 0.6 GO:0005663 DNA replication factor C complex(GO:0005663)
0.1 0.4 GO:1990682 CSF1-CSF1R complex(GO:1990682)
0.1 0.5 GO:0008537 proteasome activator complex(GO:0008537)
0.1 0.3 GO:0072559 NLRP3 inflammasome complex(GO:0072559)
0.1 0.2 GO:0043614 multi-eIF complex(GO:0043614)
0.1 1.2 GO:0044754 autolysosome(GO:0044754)
0.1 0.3 GO:0090661 box H/ACA telomerase RNP complex(GO:0090661)
0.1 0.3 GO:0017177 glucosidase II complex(GO:0017177)
0.0 0.3 GO:0071256 Sec61 translocon complex(GO:0005784) translocon complex(GO:0071256)
0.0 0.1 GO:1904511 cortical microtubule plus-end(GO:1903754) cytoplasmic microtubule plus-end(GO:1904511)
0.0 0.3 GO:0005638 lamin filament(GO:0005638)
0.0 0.1 GO:1990666 PCSK9-LDLR complex(GO:1990666)
0.0 0.4 GO:0005742 mitochondrial outer membrane translocase complex(GO:0005742)
0.0 0.5 GO:0017101 aminoacyl-tRNA synthetase multienzyme complex(GO:0017101)
0.0 0.1 GO:0043202 lysosomal lumen(GO:0043202)
0.0 2.0 GO:0022627 cytosolic small ribosomal subunit(GO:0022627)
0.0 0.1 GO:0071821 FANCM-MHF complex(GO:0071821)
0.0 0.2 GO:0031251 PAN complex(GO:0031251)
0.0 0.4 GO:0005688 U6 snRNP(GO:0005688)
0.0 1.0 GO:0005868 cytoplasmic dynein complex(GO:0005868)
0.0 1.6 GO:0005637 nuclear inner membrane(GO:0005637)
0.0 0.1 GO:0005672 transcription factor TFIIA complex(GO:0005672)
0.0 0.3 GO:1990462 omegasome(GO:1990462)
0.0 0.2 GO:0097550 transcriptional preinitiation complex(GO:0097550)
0.0 0.4 GO:0000177 cytoplasmic exosome (RNase complex)(GO:0000177)
0.0 0.5 GO:0005839 proteasome core complex(GO:0005839)
0.0 0.2 GO:0031390 Ctf18 RFC-like complex(GO:0031390)
0.0 0.1 GO:0097132 cyclin D2-CDK6 complex(GO:0097132)
0.0 0.4 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.2 GO:0036157 outer dynein arm(GO:0036157)
0.0 0.1 GO:0044530 supraspliceosomal complex(GO:0044530)
0.0 0.2 GO:0070695 FHF complex(GO:0070695)
0.0 0.2 GO:0030915 Smc5-Smc6 complex(GO:0030915)
0.0 0.1 GO:0033179 proton-transporting V-type ATPase, V0 domain(GO:0033179)
0.0 0.2 GO:0002193 MAML1-RBP-Jkappa- ICN1 complex(GO:0002193)
0.0 0.1 GO:0005947 mitochondrial alpha-ketoglutarate dehydrogenase complex(GO:0005947)
0.0 0.3 GO:0000778 condensed nuclear chromosome kinetochore(GO:0000778)
0.0 0.2 GO:0031315 extrinsic component of mitochondrial outer membrane(GO:0031315)
0.0 0.4 GO:0031083 BLOC-1 complex(GO:0031083)
0.0 0.6 GO:0000159 protein phosphatase type 2A complex(GO:0000159)
0.0 0.1 GO:0030868 smooth endoplasmic reticulum membrane(GO:0030868) smooth endoplasmic reticulum part(GO:0097425)
0.0 0.5 GO:0005665 DNA-directed RNA polymerase II, core complex(GO:0005665)
0.0 0.5 GO:0071782 endoplasmic reticulum tubular network(GO:0071782)
0.0 0.1 GO:0000347 THO complex(GO:0000347) THO complex part of transcription export complex(GO:0000445)
0.0 0.2 GO:0072669 tRNA-splicing ligase complex(GO:0072669)
0.0 0.4 GO:0016471 vacuolar proton-transporting V-type ATPase complex(GO:0016471)
0.0 0.1 GO:0098837 postsynaptic recycling endosome(GO:0098837)
0.0 0.2 GO:0034663 endoplasmic reticulum chaperone complex(GO:0034663)
0.0 0.2 GO:0030681 ribonuclease P complex(GO:0030677) multimeric ribonuclease P complex(GO:0030681)
0.0 0.3 GO:0000124 SAGA complex(GO:0000124)
0.0 0.2 GO:0005787 signal peptidase complex(GO:0005787)
0.0 0.1 GO:1990037 Lewy body core(GO:1990037)
0.0 0.1 GO:0031265 CD95 death-inducing signaling complex(GO:0031265)
0.0 0.1 GO:0061617 MICOS complex(GO:0061617)
0.0 0.2 GO:0031462 Cul2-RING ubiquitin ligase complex(GO:0031462)
0.0 0.2 GO:0042599 lamellar body(GO:0042599)
0.0 0.1 GO:0071438 invadopodium membrane(GO:0071438)
0.0 0.5 GO:0005788 endoplasmic reticulum lumen(GO:0005788)
0.0 0.1 GO:0005726 perichromatin fibrils(GO:0005726)
0.0 6.6 GO:0005789 endoplasmic reticulum membrane(GO:0005789)
0.0 0.2 GO:0005952 cAMP-dependent protein kinase complex(GO:0005952)
0.0 0.2 GO:0042622 photoreceptor outer segment membrane(GO:0042622)
0.0 0.1 GO:0034045 pre-autophagosomal structure membrane(GO:0034045)
0.0 1.0 GO:0005643 nuclear pore(GO:0005643)
0.0 1.5 GO:0032587 ruffle membrane(GO:0032587)
0.0 0.1 GO:0097129 cyclin D2-CDK4 complex(GO:0097129)
0.0 0.1 GO:0070826 paraferritin complex(GO:0070826)
0.0 0.2 GO:0030061 mitochondrial crista(GO:0030061)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.4 1.3 GO:0015433 peptide antigen-transporting ATPase activity(GO:0015433) tapasin binding(GO:0046980)
0.3 0.9 GO:0005174 CD40 receptor binding(GO:0005174)
0.3 1.4 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.3 4.4 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.2 1.0 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.2 2.2 GO:0001730 2'-5'-oligoadenylate synthetase activity(GO:0001730)
0.2 1.1 GO:0004483 mRNA (nucleoside-2'-O-)-methyltransferase activity(GO:0004483)
0.2 0.5 GO:0030337 DNA polymerase processivity factor activity(GO:0030337)
0.2 2.0 GO:0070181 small ribosomal subunit rRNA binding(GO:0070181)
0.2 0.8 GO:0004839 ubiquitin activating enzyme activity(GO:0004839)
0.1 0.4 GO:0005157 macrophage colony-stimulating factor receptor binding(GO:0005157)
0.1 0.6 GO:0008160 protein tyrosine phosphatase activator activity(GO:0008160)
0.1 0.4 GO:0004798 thymidylate kinase activity(GO:0004798)
0.1 0.8 GO:0004032 alditol:NADP+ 1-oxidoreductase activity(GO:0004032)
0.1 0.7 GO:0032450 maltose alpha-glucosidase activity(GO:0032450)
0.1 1.3 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.1 0.8 GO:0031849 olfactory receptor binding(GO:0031849)
0.1 0.3 GO:0004800 thyroxine 5'-deiodinase activity(GO:0004800)
0.1 0.4 GO:0000010 trans-hexaprenyltranstransferase activity(GO:0000010) trans-octaprenyltranstransferase activity(GO:0050347)
0.1 2.0 GO:0042605 peptide antigen binding(GO:0042605)
0.1 2.5 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.1 2.2 GO:0004298 threonine-type endopeptidase activity(GO:0004298) threonine-type peptidase activity(GO:0070003)
0.1 1.0 GO:0050700 CARD domain binding(GO:0050700)
0.1 0.3 GO:0004830 tryptophan-tRNA ligase activity(GO:0004830)
0.1 0.8 GO:0061133 endopeptidase activator activity(GO:0061133)
0.1 0.9 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.1 0.2 GO:0031798 type 1 metabotropic glutamate receptor binding(GO:0031798) RNA polymerase II transcription factor activity, estrogen-activated sequence-specific DNA binding(GO:0038052)
0.1 0.2 GO:0004658 propionyl-CoA carboxylase activity(GO:0004658)
0.1 0.4 GO:0000099 sulfur amino acid transmembrane transporter activity(GO:0000099)
0.1 0.1 GO:0009041 uridylate kinase activity(GO:0009041)
0.1 0.2 GO:0032394 MHC class Ib receptor activity(GO:0032394)
0.1 0.1 GO:0004819 glutamine-tRNA ligase activity(GO:0004819)
0.1 0.2 GO:0000179 rRNA (adenine-N6,N6-)-dimethyltransferase activity(GO:0000179)
0.1 0.3 GO:0072345 NAADP-sensitive calcium-release channel activity(GO:0072345)
0.1 0.6 GO:0003689 DNA clamp loader activity(GO:0003689) protein-DNA loading ATPase activity(GO:0033170)
0.1 0.4 GO:1901612 cardiolipin binding(GO:1901612)
0.1 0.3 GO:0090599 alpha-glucosidase activity(GO:0090599)
0.1 0.6 GO:0008454 alpha-1,3-mannosylglycoprotein 4-beta-N-acetylglucosaminyltransferase activity(GO:0008454)
0.1 0.4 GO:0061513 hexose phosphate transmembrane transporter activity(GO:0015119) organophosphate:inorganic phosphate antiporter activity(GO:0015315) hexose-phosphate:inorganic phosphate antiporter activity(GO:0015526) glucose 6-phosphate:inorganic phosphate antiporter activity(GO:0061513)
0.1 0.2 GO:0004637 phosphoribosylamine-glycine ligase activity(GO:0004637)
0.1 0.3 GO:0008597 calcium-dependent protein serine/threonine phosphatase regulator activity(GO:0008597)
0.1 0.2 GO:0045142 triplex DNA binding(GO:0045142)
0.1 0.4 GO:1990825 sequence-specific mRNA binding(GO:1990825)
0.0 0.2 GO:0046979 TAP1 binding(GO:0046978) TAP2 binding(GO:0046979)
0.0 1.4 GO:0005521 lamin binding(GO:0005521)
0.0 0.2 GO:0004814 arginine-tRNA ligase activity(GO:0004814)
0.0 0.3 GO:0033743 peptide-methionine (R)-S-oxide reductase activity(GO:0033743)
0.0 0.4 GO:0015288 porin activity(GO:0015288)
0.0 16.2 GO:0003924 GTPase activity(GO:0003924)
0.0 0.2 GO:0004694 eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0 0.1 GO:0016749 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.0 0.1 GO:0033149 FFAT motif binding(GO:0033149)
0.0 0.4 GO:0043023 ribosomal large subunit binding(GO:0043023)
0.0 0.1 GO:0003863 alpha-ketoacid dehydrogenase activity(GO:0003826) 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) activity(GO:0003863)
0.0 0.3 GO:0034513 box H/ACA snoRNA binding(GO:0034513)
0.0 0.1 GO:0003844 1,4-alpha-glucan branching enzyme activity(GO:0003844)
0.0 0.1 GO:0004910 interleukin-1, Type II, blocking receptor activity(GO:0004910)
0.0 0.1 GO:0002114 interleukin-33 receptor activity(GO:0002114)
0.0 4.2 GO:0003727 single-stranded RNA binding(GO:0003727)
0.0 0.2 GO:0052650 NADP-retinol dehydrogenase activity(GO:0052650)
0.0 0.7 GO:0005527 macrolide binding(GO:0005527) FK506 binding(GO:0005528)
0.0 0.1 GO:0016635 oxidoreductase activity, acting on the CH-CH group of donors, quinone or related compound as acceptor(GO:0016635)
0.0 0.2 GO:0004359 glutaminase activity(GO:0004359)
0.0 0.1 GO:0008775 acetate CoA-transferase activity(GO:0008775)
0.0 0.5 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.1 GO:0031852 mu-type opioid receptor binding(GO:0031852)
0.0 0.3 GO:0017154 semaphorin receptor activity(GO:0017154)
0.0 0.3 GO:0048019 receptor antagonist activity(GO:0048019)
0.0 0.1 GO:0004022 alcohol dehydrogenase (NAD) activity(GO:0004022)
0.0 0.1 GO:0016426 tRNA (adenine) methyltransferase activity(GO:0016426)
0.0 0.1 GO:0070976 TIR domain binding(GO:0070976)
0.0 0.1 GO:0047192 1-alkylglycerophosphocholine O-acetyltransferase activity(GO:0047192)
0.0 0.1 GO:0001512 dihydronicotinamide riboside quinone reductase activity(GO:0001512) melatonin binding(GO:1904408)
0.0 0.1 GO:0042296 ISG15 transferase activity(GO:0042296)
0.0 0.4 GO:0031386 protein tag(GO:0031386)
0.0 0.1 GO:0030375 thyroid hormone receptor coactivator activity(GO:0030375)
0.0 0.1 GO:0033142 progesterone receptor binding(GO:0033142)
0.0 0.1 GO:0004832 valine-tRNA ligase activity(GO:0004832)
0.0 0.3 GO:0031681 G-protein beta-subunit binding(GO:0031681)
0.0 0.1 GO:0008503 benzodiazepine receptor activity(GO:0008503)
0.0 0.1 GO:0016833 oxo-acid-lyase activity(GO:0016833)
0.0 0.1 GO:0000702 oxidized base lesion DNA N-glycosylase activity(GO:0000702)
0.0 0.1 GO:0008761 UDP-N-acetylglucosamine 2-epimerase activity(GO:0008761)
0.0 0.1 GO:0016401 palmitoyl-CoA oxidase activity(GO:0016401)
0.0 0.1 GO:0004769 steroid delta-isomerase activity(GO:0004769)
0.0 0.1 GO:0031735 CCR10 chemokine receptor binding(GO:0031735)
0.0 0.2 GO:0016886 ligase activity, forming phosphoric ester bonds(GO:0016886)
0.0 0.1 GO:0035175 histone kinase activity (H3-S10 specific)(GO:0035175)
0.0 0.1 GO:0098770 FBXO family protein binding(GO:0098770)
0.0 0.2 GO:0016174 NAD(P)H oxidase activity(GO:0016174)
0.0 0.1 GO:0070569 uridylyltransferase activity(GO:0070569)
0.0 0.7 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.2 GO:0004439 phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity(GO:0004439)
0.0 0.1 GO:0060698 endoribonuclease inhibitor activity(GO:0060698)
0.0 0.1 GO:0019966 interleukin-1 binding(GO:0019966)
0.0 0.1 GO:0030171 voltage-gated proton channel activity(GO:0030171)
0.0 0.5 GO:0046961 proton-transporting ATPase activity, rotational mechanism(GO:0046961)
0.0 0.0 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.0 0.3 GO:0003951 NAD+ kinase activity(GO:0003951)
0.0 0.2 GO:0004526 ribonuclease P activity(GO:0004526)
0.0 0.1 GO:1904121 propanoyl-CoA C-acyltransferase activity(GO:0033814) propionyl-CoA C2-trimethyltridecanoyltransferase activity(GO:0050632) phosphatidylethanolamine transporter activity(GO:1904121)
0.0 0.1 GO:0005166 neurotrophin p75 receptor binding(GO:0005166)
0.0 0.5 GO:0005159 insulin-like growth factor receptor binding(GO:0005159)
0.0 0.1 GO:0035662 Toll-like receptor 4 binding(GO:0035662)
0.0 0.6 GO:0030332 cyclin binding(GO:0030332)
0.0 0.1 GO:0042903 tubulin deacetylase activity(GO:0042903)
0.0 0.3 GO:0016493 C-C chemokine receptor activity(GO:0016493)
0.0 0.3 GO:0004653 polypeptide N-acetylgalactosaminyltransferase activity(GO:0004653)
0.0 0.6 GO:0016538 cyclin-dependent protein serine/threonine kinase regulator activity(GO:0016538)
0.0 0.0 GO:0004912 interleukin-3 receptor activity(GO:0004912) interleukin-3 binding(GO:0019978)
0.0 0.0 GO:0004619 bisphosphoglycerate mutase activity(GO:0004082) phosphoglycerate mutase activity(GO:0004619) 2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity(GO:0046538)
0.0 0.3 GO:0051400 BH domain binding(GO:0051400)
0.0 0.1 GO:0043515 kinetochore binding(GO:0043515)
0.0 0.1 GO:0004095 carnitine O-palmitoyltransferase activity(GO:0004095) O-palmitoyltransferase activity(GO:0016416)
0.0 1.6 GO:0101005 thiol-dependent ubiquitinyl hydrolase activity(GO:0036459) ubiquitinyl hydrolase activity(GO:0101005)
0.0 0.3 GO:0017128 phospholipid scramblase activity(GO:0017128)
0.0 0.1 GO:0001515 opioid peptide activity(GO:0001515)
0.0 0.0 GO:0050785 advanced glycation end-product receptor activity(GO:0050785)
0.0 0.6 GO:0043015 gamma-tubulin binding(GO:0043015)
0.0 0.0 GO:0005171 hepatocyte growth factor receptor binding(GO:0005171)
0.0 0.3 GO:0051010 microtubule plus-end binding(GO:0051010)
0.0 0.1 GO:0016936 galactoside binding(GO:0016936)
0.0 0.1 GO:0089720 caspase binding(GO:0089720)
0.0 0.7 GO:0019843 rRNA binding(GO:0019843)
0.0 0.2 GO:0009931 calcium-dependent protein serine/threonine kinase activity(GO:0009931)
0.0 0.1 GO:0004920 interleukin-10 receptor activity(GO:0004920)
0.0 0.3 GO:0017166 vinculin binding(GO:0017166)
0.0 0.1 GO:0019869 chloride channel inhibitor activity(GO:0019869)
0.0 0.1 GO:0015086 cadmium ion transmembrane transporter activity(GO:0015086) lead ion transmembrane transporter activity(GO:0015094) vanadium ion transmembrane transporter activity(GO:0015100) ferrous iron uptake transmembrane transporter activity(GO:0015639)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 1.6 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.1 1.8 PID IL27 PATHWAY IL27-mediated signaling events
0.0 2.1 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 0.5 SA MMP CYTOKINE CONNECTION Cytokines can induce activation of matrix metalloproteinases, which degrade extracellular matrix.
0.0 2.5 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes
0.0 0.4 SA REG CASCADE OF CYCLIN EXPR Expression of cyclins regulates progression through the cell cycle by activating cyclin-dependent kinases.
0.0 0.7 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.9 PID IFNG PATHWAY IFN-gamma pathway
0.0 0.8 ST WNT CA2 CYCLIC GMP PATHWAY Wnt/Ca2+/cyclic GMP signaling.
0.0 1.1 PID CXCR3 PATHWAY CXCR3-mediated signaling events
0.0 0.3 PID TCR CALCIUM PATHWAY Calcium signaling in the CD4+ TCR pathway
0.0 0.1 PID INTEGRIN A4B1 PATHWAY Alpha4 beta1 integrin signaling events
0.0 0.9 PID FANCONI PATHWAY Fanconi anemia pathway
0.0 1.6 SIG PIP3 SIGNALING IN CARDIAC MYOCTES Genes related to PIP3 signaling in cardiac myocytes
0.0 0.3 PID P38 MKK3 6PATHWAY p38 MAPK signaling pathway
0.0 0.1 SA G2 AND M PHASES Cdc25 activates the cdc2/cyclin B complex to induce the G2/M transition.
0.0 0.4 PID IL1 PATHWAY IL1-mediated signaling events

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.6 REACTOME DIGESTION OF DIETARY CARBOHYDRATE Genes involved in Digestion of dietary carbohydrate
0.1 2.7 REACTOME TRAF6 MEDIATED IRF7 ACTIVATION Genes involved in TRAF6 mediated IRF7 activation
0.1 1.3 REACTOME ER PHAGOSOME PATHWAY Genes involved in ER-Phagosome pathway
0.1 8.7 REACTOME INTERFERON ALPHA BETA SIGNALING Genes involved in Interferon alpha/beta signaling
0.1 1.2 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.1 3.2 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.1 1.9 REACTOME PRE NOTCH TRANSCRIPTION AND TRANSLATION Genes involved in Pre-NOTCH Transcription and Translation
0.1 1.0 REACTOME POL SWITCHING Genes involved in Polymerase switching
0.1 0.8 REACTOME REGULATION OF COMPLEMENT CASCADE Genes involved in Regulation of Complement cascade
0.0 1.0 REACTOME CYTOSOLIC TRNA AMINOACYLATION Genes involved in Cytosolic tRNA aminoacylation
0.0 2.2 REACTOME FORMATION OF THE TERNARY COMPLEX AND SUBSEQUENTLY THE 43S COMPLEX Genes involved in Formation of the ternary complex, and subsequently, the 43S complex
0.0 0.5 REACTOME THE NLRP3 INFLAMMASOME Genes involved in The NLRP3 inflammasome
0.0 0.9 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 1.1 REACTOME NEGATIVE REGULATORS OF RIG I MDA5 SIGNALING Genes involved in Negative regulators of RIG-I/MDA5 signaling
0.0 0.5 REACTOME RIG I MDA5 MEDIATED INDUCTION OF IFN ALPHA BETA PATHWAYS Genes involved in RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways
0.0 0.5 REACTOME VIRAL MESSENGER RNA SYNTHESIS Genes involved in Viral Messenger RNA Synthesis
0.0 0.6 REACTOME N GLYCAN ANTENNAE ELONGATION Genes involved in N-Glycan antennae elongation
0.0 0.3 REACTOME EXTENSION OF TELOMERES Genes involved in Extension of Telomeres
0.0 0.5 REACTOME PROLACTIN RECEPTOR SIGNALING Genes involved in Prolactin receptor signaling
0.0 0.3 REACTOME CALNEXIN CALRETICULIN CYCLE Genes involved in Calnexin/calreticulin cycle
0.0 0.1 REACTOME INFLAMMASOMES Genes involved in Inflammasomes
0.0 0.3 REACTOME MITOCHONDRIAL FATTY ACID BETA OXIDATION Genes involved in Mitochondrial Fatty Acid Beta-Oxidation
0.0 0.4 REACTOME GLUTAMATE NEUROTRANSMITTER RELEASE CYCLE Genes involved in Glutamate Neurotransmitter Release Cycle
0.0 0.4 REACTOME ACTIVATED TAK1 MEDIATES P38 MAPK ACTIVATION Genes involved in activated TAK1 mediates p38 MAPK activation
0.0 0.3 REACTOME AMINE DERIVED HORMONES Genes involved in Amine-derived hormones
0.0 0.4 REACTOME CELL EXTRACELLULAR MATRIX INTERACTIONS Genes involved in Cell-extracellular matrix interactions
0.0 0.5 REACTOME EFFECTS OF PIP2 HYDROLYSIS Genes involved in Effects of PIP2 hydrolysis
0.0 0.3 REACTOME OTHER SEMAPHORIN INTERACTIONS Genes involved in Other semaphorin interactions
0.0 0.3 REACTOME FANCONI ANEMIA PATHWAY Genes involved in Fanconi Anemia pathway
0.0 0.2 REACTOME KERATAN SULFATE DEGRADATION Genes involved in Keratan sulfate degradation
0.0 0.4 REACTOME CHOLESTEROL BIOSYNTHESIS Genes involved in Cholesterol biosynthesis
0.0 0.3 REACTOME IL1 SIGNALING Genes involved in Interleukin-1 signaling
0.0 0.4 REACTOME INSULIN RECEPTOR RECYCLING Genes involved in Insulin receptor recycling