Project

avrg: GFI1 WT vs 36n/n vs KD

Navigation
Downloads

Results for Irf4

Z-value: 1.36

Motif logo

Transcription factors associated with Irf4

Gene Symbol Gene ID Gene Info
ENSMUSG00000021356.11 interferon regulatory factor 4

Activity-expression correlation:

GenePromoterPearson corr. coef.P-valuePlot
Irf4mm39_v1_chr13_+_30933209_30933290-0.642.4e-01Click!

Activity profile of Irf4 motif

Sorted Z-values of Irf4 motif

Promoter Log-likelihood Transcript Gene Gene Info
chr3_+_142202642 1.38 ENSMUST00000090127.7
guanylate binding protein 5
chr11_+_48977852 0.97 ENSMUST00000046704.7
ENSMUST00000203810.3
ENSMUST00000203149.3
interferon gamma inducible protein 47
olfactory receptor 56
chr17_+_35780977 0.94 ENSMUST00000174525.8
ENSMUST00000068291.7
histocompatibility 2, Q region locus 10
chr12_-_110662256 0.84 ENSMUST00000149189.2
heat shock protein 90, alpha (cytosolic), class A member 1
chr10_+_82696135 0.83 ENSMUST00000219442.3
thioredoxin reductase 1
chrX_+_138464065 0.78 ENSMUST00000113027.8
ring finger protein 128
chr15_-_76127600 0.76 ENSMUST00000165738.8
ENSMUST00000075689.7
poly (ADP-ribose) polymerase family, member 10
chr17_+_35481702 0.74 ENSMUST00000172785.8
histocompatibility 2, D region locus 1
chr6_+_116528102 0.74 ENSMUST00000122096.3
eukaryotic translation initiation factor 4A3 like 2
chr11_+_48977888 0.71 ENSMUST00000214804.2
interferon gamma inducible protein 47
chrX_+_93679671 0.67 ENSMUST00000096368.4
G1 to S phase transition 2
chr2_-_127630769 0.63 ENSMUST00000028857.14
ENSMUST00000110357.2
nephronophthisis 1 (juvenile) homolog (human)
chr19_-_4976844 0.62 ENSMUST00000236496.2
dipeptidylpeptidase 3
chr19_-_3955230 0.62 ENSMUST00000145791.8
T cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 protein A3
chr17_-_30831576 0.58 ENSMUST00000235171.2
ENSMUST00000236335.2
ENSMUST00000167624.2
glyoxalase 1
chrM_+_8603 0.57 ENSMUST00000082409.1
mitochondrially encoded cytochrome c oxidase III
chr11_+_87938626 0.56 ENSMUST00000107920.10
serine and arginine-rich splicing factor 1
chr1_-_160898181 0.55 ENSMUST00000035430.4
aspartyl-tRNA synthetase 2 (mitochondrial)
chr3_+_27371168 0.55 ENSMUST00000046383.12
tumor necrosis factor (ligand) superfamily, member 10
chr19_+_56385531 0.52 ENSMUST00000026062.10
caspase 7
chr19_+_46611826 0.52 ENSMUST00000111855.5
WW domain binding protein 1 like
chr13_-_19579898 0.50 ENSMUST00000197565.3
ENSMUST00000221380.2
ENSMUST00000200323.3
ENSMUST00000199924.2
ENSMUST00000222869.2
STARD3 N-terminal like
chr4_-_123033721 0.49 ENSMUST00000030404.5
peptidylprolyl isomerase E (cyclophilin E)
chr18_-_43610829 0.47 ENSMUST00000057110.11
eukaryotic translation initiation factor 3, subunit J2
chr4_-_136613498 0.47 ENSMUST00000046384.9
complement component 1, q subcomponent, beta polypeptide
chrX_+_158086253 0.46 ENSMUST00000112491.2
ribosomal protein S6 kinase polypeptide 3
chr3_+_89328926 0.44 ENSMUST00000094378.10
ENSMUST00000137793.2
src homology 2 domain-containing transforming protein C1
chr1_+_52158721 0.41 ENSMUST00000186057.7
signal transducer and activator of transcription 1
chr6_-_39095144 0.40 ENSMUST00000038398.7
poly (ADP-ribose) polymerase family, member 12
chr1_+_160898283 0.40 ENSMUST00000028035.14
ENSMUST00000111620.10
ENSMUST00000111618.8
centromere protein L
chr8_+_79236051 0.38 ENSMUST00000209992.2
solute carrier family 10 (sodium/bile acid cotransporter family), member 7
chr11_+_87938128 0.37 ENSMUST00000139129.9
serine and arginine-rich splicing factor 1
chr17_-_35081456 0.37 ENSMUST00000025229.11
ENSMUST00000176203.9
ENSMUST00000128767.8
complement factor B
chr3_+_68598757 0.37 ENSMUST00000107816.4
interleukin 12a
chr13_-_19579961 0.36 ENSMUST00000039694.13
STARD3 N-terminal like
chr11_+_87938519 0.36 ENSMUST00000079866.11
serine and arginine-rich splicing factor 1
chr5_-_92496730 0.36 ENSMUST00000038816.13
ENSMUST00000118006.3
chemokine (C-X-C motif) ligand 10
chr5_+_24598633 0.35 ENSMUST00000138168.3
ENSMUST00000115077.8
ATP-binding cassette, sub-family B (MDR/TAP), member 8
chr4_-_132990362 0.35 ENSMUST00000105908.10
ENSMUST00000030674.8
synaptotagmin-like 1
chr15_+_84921283 0.35 ENSMUST00000023069.9
family with sequence similarity 118, member A
chr9_+_14187597 0.35 ENSMUST00000208222.2
sestrin 3
chr8_+_62381115 0.35 ENSMUST00000154398.8
ENSMUST00000156980.8
ENSMUST00000093485.3
ENSMUST00000070631.15
DExD/H box helicase 60
chr1_+_52158599 0.34 ENSMUST00000186574.7
ENSMUST00000070968.14
ENSMUST00000191435.7
ENSMUST00000186857.7
ENSMUST00000188681.7
signal transducer and activator of transcription 1
chr19_-_24202344 0.34 ENSMUST00000099558.5
ENSMUST00000232956.2
tight junction protein 2
chr16_+_35759346 0.33 ENSMUST00000023622.13
poly (ADP-ribose) polymerase family, member 9
chr13_-_23894697 0.33 ENSMUST00000091707.13
ENSMUST00000006787.8
homeostatic iron regulator
chr15_+_102391614 0.32 ENSMUST00000229432.2
poly(rC) binding protein 2
chr7_-_28441173 0.32 ENSMUST00000171183.2
mitochondrial ribosomal protein S12
chr7_+_79836581 0.32 ENSMUST00000032754.9
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B
chr10_-_53952686 0.31 ENSMUST00000220088.2
mannosidase 1, alpha
chr17_-_35081129 0.30 ENSMUST00000154526.8
complement factor B
chr1_+_52158693 0.30 ENSMUST00000189347.7
signal transducer and activator of transcription 1
chr11_+_78234300 0.29 ENSMUST00000002127.14
ENSMUST00000108295.8
unc-119 lipid binding chaperone
chr13_-_30170031 0.28 ENSMUST00000102948.11
E2F transcription factor 3
chr2_+_29825427 0.28 ENSMUST00000019859.9
GLE1 RNA export mediator (yeast)
chr9_-_35179042 0.26 ENSMUST00000217306.2
ENSMUST00000125087.2
ENSMUST00000121564.8
ENSMUST00000063782.12
ENSMUST00000059057.14
family with sequence similarity 118, member B
chr7_-_5128936 0.26 ENSMUST00000147835.4
RAS-like, family 2, locus 9
chr2_+_38401826 0.26 ENSMUST00000112895.8
NIMA (never in mitosis gene a)-related expressed kinase 6
chr2_-_131016573 0.26 ENSMUST00000127987.2
sperm flagellar 1
chr8_-_79547707 0.25 ENSMUST00000130325.8
ENSMUST00000051867.7
LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated
chr15_-_97603664 0.25 ENSMUST00000023104.7
RNA polymerase II associated protein 3
chr3_-_108108113 0.25 ENSMUST00000106655.2
ENSMUST00000065664.7
cytochrome b-561 domain containing 1
chr14_+_55815999 0.25 ENSMUST00000172738.2
ENSMUST00000089619.13
proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
chr11_-_101442663 0.23 ENSMUST00000017290.11
breast cancer 1, early onset
chr14_+_55815879 0.23 ENSMUST00000174563.8
proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
chr1_-_97904958 0.22 ENSMUST00000161567.8
peptidylglycine alpha-amidating monooxygenase
chr7_-_28441205 0.21 ENSMUST00000056078.9
mitochondrial ribosomal protein S12
chr14_-_78970160 0.21 ENSMUST00000226342.3
diacylglycerol kinase, eta
chrM_+_9459 0.21 ENSMUST00000082411.1
mitochondrially encoded NADH dehydrogenase 3
chr8_-_46577183 0.21 ENSMUST00000170416.8
sorting nexin 25
chr9_-_107419309 0.21 ENSMUST00000195235.6
cytochrome b-561 domain containing 2
chr3_+_27371206 0.20 ENSMUST00000174840.2
tumor necrosis factor (ligand) superfamily, member 10
chr8_+_105897300 0.19 ENSMUST00000052209.9
ENSMUST00000109392.9
ENSMUST00000109395.8
core binding factor beta
chr11_-_107361525 0.19 ENSMUST00000103064.10
phosphatidylinositol transfer protein, cytoplasmic 1
chr7_-_4448631 0.19 ENSMUST00000008579.14
retinol dehydrogenase 13 (all-trans and 9-cis)
chr1_+_57445487 0.17 ENSMUST00000027114.6
matrix AAA peptidase interacting protein 1
chr5_-_92653377 0.17 ENSMUST00000031377.9
scavenger receptor class B, member 2
chr14_+_55815580 0.17 ENSMUST00000174484.8
proteasome (prosome, macropain) activator subunit 1 (PA28 alpha)
chr9_-_110886306 0.16 ENSMUST00000195968.2
ENSMUST00000111888.3
chemokine (C-C motif) receptor-like 2
chrX_+_20714782 0.16 ENSMUST00000001155.11
ENSMUST00000122312.8
ENSMUST00000120356.8
ENSMUST00000122850.2
Araf proto-oncogene, serine/threonine kinase
chr6_-_49191891 0.16 ENSMUST00000031838.9
insulin-like growth factor 2 mRNA binding protein 3
chr18_-_70663209 0.16 ENSMUST00000161542.8
ENSMUST00000159389.8
polymerase (DNA directed), iota
chr2_-_152673032 0.16 ENSMUST00000128172.3
BCL2-like 1
chr6_-_124888643 0.16 ENSMUST00000032217.2
lymphocyte-activation gene 3
chr8_-_106665060 0.16 ENSMUST00000034369.10
proteasome (prosome, macropain) subunit, beta type 10
chr2_+_22959223 0.15 ENSMUST00000114523.10
acyl-Coenzyme A binding domain containing 5
chr3_-_148696155 0.15 ENSMUST00000196526.5
ENSMUST00000200543.5
ENSMUST00000200154.5
adhesion G protein-coupled receptor L2
chr2_+_109522781 0.14 ENSMUST00000111050.10
brain derived neurotrophic factor
chr2_+_38401655 0.14 ENSMUST00000054234.10
ENSMUST00000112902.8
NIMA (never in mitosis gene a)-related expressed kinase 6
chr1_-_161704224 0.14 ENSMUST00000048377.11
SUN domain containing ossification factor
chr11_+_48977495 0.14 ENSMUST00000152914.2
interferon gamma inducible protein 47
chr1_-_75293637 0.13 ENSMUST00000185419.7
ENSMUST00000187000.7
aspartyl aminopeptidase
chr5_-_104169785 0.13 ENSMUST00000031251.16
hydroxysteroid (17-beta) dehydrogenase 11
chr2_-_51824656 0.13 ENSMUST00000165313.2
RNA binding motif protein 43
chr2_+_22959452 0.13 ENSMUST00000155602.4
acyl-Coenzyme A binding domain containing 5
chr13_+_20274708 0.12 ENSMUST00000072519.7
engulfment and cell motility 1
chr17_-_7050145 0.12 ENSMUST00000064234.7
ezrin
chr6_-_70313491 0.12 ENSMUST00000103388.4
immunoglobulin kappa variable 6-20
chr19_-_57185988 0.12 ENSMUST00000099294.9
actin-binding LIM protein 1
chr11_+_78136569 0.11 ENSMUST00000002133.9
stromal cell derived factor 2
chr2_+_71283620 0.11 ENSMUST00000037210.9
methionyl aminopeptidase type 1D (mitochondrial)
chr4_-_4138817 0.11 ENSMUST00000133567.2
preproenkephalin
chr2_-_52225146 0.11 ENSMUST00000075301.10
nebulin
chr4_-_156285247 0.11 ENSMUST00000085425.6
ISG15 ubiquitin-like modifier
chrX_+_135608725 0.11 ENSMUST00000055104.6
transcription elongation factor A (SII)-like 1
chr1_+_74627445 0.11 ENSMUST00000113733.10
ENSMUST00000027358.11
BCS1-like (yeast)
chr13_-_23894828 0.10 ENSMUST00000091706.14
homeostatic iron regulator
chr10_+_28544356 0.10 ENSMUST00000060409.13
ENSMUST00000056097.11
ENSMUST00000105516.9
thymocyte selection associated
chr3_+_152052102 0.10 ENSMUST00000117492.9
ENSMUST00000026507.13
ENSMUST00000197748.5
ubiquitin specific peptidase 33
chrX_+_149330371 0.10 ENSMUST00000066337.13
ENSMUST00000112715.2
aminolevulinic acid synthase 2, erythroid
chr7_-_126194097 0.10 ENSMUST00000058429.6
interleukin 27
chr9_+_58536386 0.09 ENSMUST00000176250.2
neuroplastin
chr1_+_175459559 0.09 ENSMUST00000040250.15
kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
chr11_+_119283887 0.09 ENSMUST00000093902.12
ENSMUST00000131035.10
ring finger protein 213
chr13_-_100753419 0.09 ENSMUST00000168772.2
ENSMUST00000163163.9
ENSMUST00000022137.14
MARVEL (membrane-associating) domain containing 2
chr14_+_103887644 0.08 ENSMUST00000069443.14
SLAIN motif family, member 1
chr19_+_41017714 0.08 ENSMUST00000051806.12
ENSMUST00000112200.3
deoxynucleotidyltransferase, terminal
chr10_+_18283405 0.07 ENSMUST00000037341.14
NHS-like 1
chr7_+_28441400 0.06 ENSMUST00000094632.6
seryl-aminoacyl-tRNA synthetase 2
chr1_-_164763091 0.06 ENSMUST00000027860.8
chemokine (C motif) ligand 1
chr9_+_108385247 0.06 ENSMUST00000207810.2
ENSMUST00000207862.2
ENSMUST00000208581.2
ENSMUST00000134939.9
ENSMUST00000207713.2
glutaminyl-tRNA synthetase
chr2_-_66240408 0.06 ENSMUST00000112366.8
sodium channel, voltage-gated, type I, alpha
chr1_+_44158111 0.06 ENSMUST00000155917.8
basic, immunoglobulin-like variable motif containing
chr17_-_20334488 0.05 ENSMUST00000095637.2
formyl peptide receptor, related sequence 7
chr18_+_37840092 0.05 ENSMUST00000195823.2
protocadherin gamma subfamily A, 6
chr7_+_126895531 0.05 ENSMUST00000170971.8
integrin alpha L
chr2_+_85597442 0.05 ENSMUST00000216397.3
olfactory receptor 1013
chr1_-_75293997 0.05 ENSMUST00000189282.3
ENSMUST00000191254.7
aspartyl aminopeptidase
chr10_+_21758083 0.04 ENSMUST00000120509.8
serum/glucocorticoid regulated kinase 1
chr14_+_65504067 0.04 ENSMUST00000224629.2
F-box protein 16
chr1_-_75293447 0.04 ENSMUST00000189551.7
aspartyl aminopeptidase
chr10_+_69048506 0.03 ENSMUST00000167384.8
Rho-related BTB domain containing 1
chr12_-_114073050 0.03 ENSMUST00000103472.4
immunoglobulin heavy variable V9-2
chr7_-_108480811 0.03 ENSMUST00000059617.2
olfactory receptor 518
chr1_-_75293942 0.03 ENSMUST00000187075.7
aspartyl aminopeptidase
chr1_-_57445576 0.03 ENSMUST00000160837.8
tRNA-yW synthesizing protein 5
chr19_-_57185861 0.03 ENSMUST00000111550.8
actin-binding LIM protein 1
chr5_-_99391073 0.03 ENSMUST00000166484.2
RasGEF domain family, member 1B
chr14_-_61283911 0.03 ENSMUST00000111234.10
ENSMUST00000224371.2
tumor necrosis factor receptor superfamily, member 19
chr2_-_113047397 0.03 ENSMUST00000080673.13
ENSMUST00000208151.2
ENSMUST00000208290.2
ryanodine receptor 3
chr16_-_58930996 0.03 ENSMUST00000076262.4
olfactory receptor 193
chr9_-_78350486 0.03 ENSMUST00000070742.14
ENSMUST00000034898.14
cyclic GMP-AMP synthase
chr19_+_47926086 0.03 ENSMUST00000238163.2
ENSMUST00000066308.9
cilia and flagella associated protein 58
chr1_-_75293589 0.03 ENSMUST00000113605.10
aspartyl aminopeptidase
chr9_+_108394761 0.03 ENSMUST00000192819.2
glutamine-rich 1
chr7_+_105024231 0.02 ENSMUST00000106805.4
predicted gene 5901
chr19_-_57185928 0.02 ENSMUST00000111544.8
actin-binding LIM protein 1
chr11_+_62711057 0.02 ENSMUST00000055006.12
ENSMUST00000072639.10
tripartite motif-containing 16
chr10_+_69048464 0.02 ENSMUST00000020101.12
Rho-related BTB domain containing 1
chr1_+_155433858 0.02 ENSMUST00000080138.13
ENSMUST00000035560.9
ENSMUST00000097529.5
acyl-Coenzyme A binding domain containing 6
chr11_+_82006001 0.02 ENSMUST00000009329.3
chemokine (C-C motif) ligand 8
chr1_-_93029547 0.02 ENSMUST00000112958.9
ENSMUST00000186861.2
ENSMUST00000171556.8
kinesin family member 1A
chr14_+_65504151 0.02 ENSMUST00000169656.3
ENSMUST00000226005.2
F-box protein 16
chr13_-_100753181 0.02 ENSMUST00000225754.2
MARVEL (membrane-associating) domain containing 2
chr9_+_5345450 0.02 ENSMUST00000151332.2
caspase 12
chr10_-_114638202 0.02 ENSMUST00000239411.2
TRH-degrading enzyme
chr15_-_98707367 0.02 ENSMUST00000230409.2
dendrin
chr11_+_49454750 0.02 ENSMUST00000204300.2
olfactory receptor 1380
chr10_-_111833138 0.01 ENSMUST00000074805.12
GLI pathogenesis-related 1 (glioma)
chr2_+_22958956 0.01 ENSMUST00000226571.2
ENSMUST00000114529.10
ENSMUST00000114526.9
ENSMUST00000228050.2
acyl-Coenzyme A binding domain containing 5
chr1_-_75293793 0.01 ENSMUST00000187836.7
aspartyl aminopeptidase
chr11_+_67212464 0.01 ENSMUST00000108684.8
myosin, heavy polypeptide 13, skeletal muscle
chr19_-_58442866 0.01 ENSMUST00000169850.8
glial cell line derived neurotrophic factor family receptor alpha 1
chr19_-_57185808 0.01 ENSMUST00000111546.8
actin-binding LIM protein 1
chr10_+_94411119 0.01 ENSMUST00000121471.8
transmembrane and coiled coil domains 3
chr18_+_37637317 0.01 ENSMUST00000052179.8
protocadherin beta 20
chr2_+_111130980 0.01 ENSMUST00000216697.2
ENSMUST00000213823.2
olfactory receptor 1279
chr10_-_52071340 0.01 ENSMUST00000020045.10
Ros1 proto-oncogene
chr19_-_58443012 0.01 ENSMUST00000129100.8
ENSMUST00000123957.2
glial cell line derived neurotrophic factor family receptor alpha 1
chr13_-_113182891 0.01 ENSMUST00000231962.2
ENSMUST00000022282.6
glutathione peroxidase 8 (putative)
chr3_+_90444537 0.01 ENSMUST00000098911.10
S100 calcium binding protein A16
chr16_-_43484494 0.01 ENSMUST00000096065.6
T cell immunoreceptor with Ig and ITIM domains
chr12_-_118930130 0.01 ENSMUST00000035515.5
ATP-binding cassette, sub-family B (MDR/TAP), member 5
chrX_-_105884178 0.01 ENSMUST00000062010.10
retrotransposon Gag like 3
chr12_-_113542610 0.01 ENSMUST00000195468.6
ENSMUST00000103442.3
immunoglobulin heavy variable 5-2
chr11_+_67212604 0.01 ENSMUST00000180845.8
myosin, heavy polypeptide 13, skeletal muscle
chr3_+_90444613 0.01 ENSMUST00000107335.2
S100 calcium binding protein A16
chr11_-_77784922 0.01 ENSMUST00000017597.5
pipecolic acid oxidase
chr8_+_46338498 0.01 ENSMUST00000034053.7
PDZ and LIM domain 3
chr15_-_101651534 0.01 ENSMUST00000023710.6
keratin 71
chr7_-_108445215 0.01 ENSMUST00000071410.2
olfactory receptor 516
chr18_-_60781365 0.01 ENSMUST00000143275.3
synaptopodin
chr9_-_117080869 0.01 ENSMUST00000172564.3
RNA binding motif, single stranded interacting protein
chr1_+_187995096 0.01 ENSMUST00000060479.14
usherin
chr17_+_38082519 0.01 ENSMUST00000119082.2
olfactory receptor 122
chr19_-_58443830 0.01 ENSMUST00000026076.14
glial cell line derived neurotrophic factor family receptor alpha 1
chr2_-_110591909 0.01 ENSMUST00000140777.2
anoctamin 3
chr10_-_107555840 0.01 ENSMUST00000050702.9
protein tyrosine phosphatase, receptor type, Q
chr15_-_58187556 0.01 ENSMUST00000022985.2
kelch-like 38
chr19_+_34618271 0.01 ENSMUST00000102824.4
interferon-induced protein with tetratricopeptide repeats 1
chr7_+_58307930 0.01 ENSMUST00000168747.3
ATPase, class V, type 10A
chr8_+_46338557 0.01 ENSMUST00000210422.2
PDZ and LIM domain 3
chr3_+_92325386 0.00 ENSMUST00000029533.3
small proline-rich protein 2J, pseudogene
chr16_+_65320163 0.00 ENSMUST00000184525.2
POU domain, class 1, transcription factor 1
chr11_+_53611611 0.00 ENSMUST00000048605.3
interleukin 5
chr10_+_56255184 0.00 ENSMUST00000220069.2
gap junction protein, alpha 1
chr17_+_23898223 0.00 ENSMUST00000024699.4
ENSMUST00000232719.2
claudin 6
chr1_+_57884693 0.00 ENSMUST00000169772.3
spermatogenesis associated, serine-rich 2-like
chr11_+_87457479 0.00 ENSMUST00000239011.2
septin 4
chr2_-_113047313 0.00 ENSMUST00000208135.2
ENSMUST00000134358.9
ryanodine receptor 3

Network of associatons between targets according to the STRING database.

First level regulatory network of Irf4

PNG image of the network

In order to view interactive SVG image please either update your browser to latest version or install SVG plugin.


View svg image
View png image

Gene Ontology Analysis

Gene overrepresentation in biological process category:

Log-likelihood per target  Total log-likelihood Term Description
0.3 1.0 GO:0034240 negative regulation of macrophage fusion(GO:0034240)
0.2 0.7 GO:0002184 cytoplasmic translational termination(GO:0002184)
0.2 0.6 GO:1903348 positive regulation of bicellular tight junction assembly(GO:1903348)
0.2 0.8 GO:0070212 regulation of chromatin assembly(GO:0010847) protein poly-ADP-ribosylation(GO:0070212)
0.1 0.7 GO:0002484 antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway(GO:0002484) antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent(GO:0002485)
0.1 1.3 GO:0000395 mRNA 5'-splice site recognition(GO:0000395)
0.1 0.4 GO:1904440 regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002589) negative regulation of antigen processing and presentation of peptide antigen via MHC class I(GO:0002590) regulation of T cell antigen processing and presentation(GO:0002625) positive regulation of iron ion transport(GO:0034758) positive regulation of iron ion transmembrane transport(GO:0034761) regulation of iron ion import(GO:1900390) regulation of ferrous iron import into cell(GO:1903989) positive regulation of ferrous iron import into cell(GO:1903991) regulation of ferrous iron binding(GO:1904432) positive regulation of ferrous iron binding(GO:1904434) regulation of transferrin receptor binding(GO:1904435) positive regulation of transferrin receptor binding(GO:1904437) regulation of ferrous iron import across plasma membrane(GO:1904438) positive regulation of ferrous iron import across plasma membrane(GO:1904440)
0.1 1.4 GO:1900227 positive regulation of NLRP3 inflammasome complex assembly(GO:1900227)
0.1 0.8 GO:0045583 regulation of cytotoxic T cell differentiation(GO:0045583) positive regulation of cytotoxic T cell differentiation(GO:0045585)
0.1 0.8 GO:0016259 selenocysteine metabolic process(GO:0016259)
0.1 0.6 GO:0006421 asparaginyl-tRNA aminoacylation(GO:0006421)
0.1 0.5 GO:0072733 response to staurosporine(GO:0072733) cellular response to staurosporine(GO:0072734)
0.1 0.4 GO:1901740 negative regulation of myoblast fusion(GO:1901740)
0.1 0.4 GO:1990839 response to endothelin(GO:1990839)
0.1 0.3 GO:2001287 negative regulation of caveolin-mediated endocytosis(GO:2001287)
0.1 0.3 GO:1900245 positive regulation of MDA-5 signaling pathway(GO:1900245)
0.1 0.6 GO:0019243 methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione(GO:0019243) methylglyoxal catabolic process(GO:0051596) methylglyoxal catabolic process to lactate(GO:0061727)
0.1 0.3 GO:0030576 Cajal body organization(GO:0030576)
0.1 0.6 GO:0007039 protein catabolic process in the vacuole(GO:0007039)
0.0 0.3 GO:2001205 negative regulation of osteoclast development(GO:2001205)
0.0 0.1 GO:0061193 taste bud development(GO:0061193)
0.0 0.2 GO:2000620 positive regulation of histone H4-K16 acetylation(GO:2000620)
0.0 0.4 GO:2000510 positive regulation of dendritic cell chemotaxis(GO:2000510)
0.0 0.2 GO:0046898 response to cycloheximide(GO:0046898)
0.0 0.7 GO:0006957 complement activation, alternative pathway(GO:0006957)
0.0 0.3 GO:0038203 TORC2 signaling(GO:0038203)
0.0 1.8 GO:0035458 cellular response to interferon-beta(GO:0035458)
0.0 0.1 GO:0006710 androgen catabolic process(GO:0006710)
0.0 0.1 GO:2000412 positive regulation of thymocyte migration(GO:2000412)
0.0 0.3 GO:0070345 negative regulation of fat cell proliferation(GO:0070345)
0.0 0.3 GO:0006449 regulation of translational termination(GO:0006449)
0.0 0.1 GO:1902896 terminal web assembly(GO:1902896)
0.0 0.2 GO:0031179 peptide modification(GO:0031179)
0.0 0.3 GO:0030242 pexophagy(GO:0030242)
0.0 0.2 GO:0009644 response to high light intensity(GO:0009644)
0.0 0.1 GO:1902683 regulation of receptor localization to synapse(GO:1902683)
0.0 0.9 GO:0002474 antigen processing and presentation of peptide antigen via MHC class I(GO:0002474)
0.0 0.3 GO:0060330 regulation of response to interferon-gamma(GO:0060330)
0.0 0.6 GO:0019884 antigen processing and presentation of exogenous antigen(GO:0019884)
0.0 0.3 GO:0097033 mitochondrial respiratory chain complex III biogenesis(GO:0097033)
0.0 0.1 GO:0006434 seryl-tRNA aminoacylation(GO:0006434)
0.0 0.9 GO:0042036 negative regulation of cytokine biosynthetic process(GO:0042036)
0.0 0.2 GO:0071494 cellular response to UV-C(GO:0071494)
0.0 0.5 GO:0000413 protein peptidyl-prolyl isomerization(GO:0000413)
0.0 0.1 GO:0032020 ISG15-protein conjugation(GO:0032020)
0.0 0.3 GO:0075522 IRES-dependent viral translational initiation(GO:0075522)
0.0 0.3 GO:0033750 ribosomal subunit export from nucleus(GO:0000054) ribosome localization(GO:0033750) establishment of ribosome localization(GO:0033753)
0.0 0.2 GO:0060394 negative regulation of pathway-restricted SMAD protein phosphorylation(GO:0060394)
0.0 0.0 GO:0031591 wybutosine metabolic process(GO:0031590) wybutosine biosynthetic process(GO:0031591)
0.0 0.2 GO:0006622 protein targeting to lysosome(GO:0006622)
0.0 0.3 GO:0006491 N-glycan processing(GO:0006491)
0.0 0.4 GO:0090200 positive regulation of release of cytochrome c from mitochondria(GO:0090200)

Gene overrepresentation in cellular component category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.7 GO:0018444 translation release factor complex(GO:0018444)
0.1 0.4 GO:0070435 Shc-EGFR complex(GO:0070435)
0.1 0.8 GO:0097226 sperm mitochondrial sheath(GO:0097226)
0.1 1.7 GO:0042612 MHC class I protein complex(GO:0042612)
0.1 0.6 GO:0008537 proteasome activator complex(GO:0008537)
0.1 0.3 GO:0044614 nuclear pore cytoplasmic filaments(GO:0044614)
0.0 0.4 GO:1990357 terminal web(GO:1990357)
0.0 0.9 GO:0044232 organelle membrane contact site(GO:0044232)
0.0 0.1 GO:0098592 cytoplasmic side of apical plasma membrane(GO:0098592)
0.0 0.2 GO:0043202 lysosomal lumen(GO:0043202)
0.0 1.3 GO:0035145 exon-exon junction complex(GO:0035145)
0.0 0.3 GO:0061700 GATOR2 complex(GO:0061700)
0.0 0.1 GO:0032280 symmetric synapse(GO:0032280)
0.0 0.3 GO:0097255 R2TP complex(GO:0097255)
0.0 0.2 GO:1990111 spermatoproteasome complex(GO:1990111)
0.0 0.5 GO:0005852 eukaryotic translation initiation factor 3 complex(GO:0005852)
0.0 0.2 GO:0070531 BRCA1-A complex(GO:0070531)
0.0 0.3 GO:0005688 U6 snRNP(GO:0005688)
0.0 0.5 GO:0000314 organellar small ribosomal subunit(GO:0000314) mitochondrial small ribosomal subunit(GO:0005763)
0.0 0.6 GO:0035869 ciliary transition zone(GO:0035869)
0.0 0.1 GO:0061689 paranodal junction(GO:0033010) tricellular tight junction(GO:0061689)

Gene overrepresentation in molecular function category:

Log-likelihood per target  Total log-likelihood Term Description
0.2 0.8 GO:0033797 selenate reductase activity(GO:0033797)
0.2 1.3 GO:0044547 DNA topoisomerase binding(GO:0044547)
0.1 2.1 GO:0030881 beta-2-microglobulin binding(GO:0030881)
0.1 0.8 GO:0002135 CTP binding(GO:0002135)
0.1 1.0 GO:0031730 CCR5 chemokine receptor binding(GO:0031730)
0.1 0.7 GO:0008079 translation release factor activity(GO:0003747) translation termination factor activity(GO:0008079)
0.1 0.4 GO:0005143 interleukin-12 receptor binding(GO:0005143)
0.1 0.4 GO:0048408 epidermal growth factor binding(GO:0048408)
0.1 0.4 GO:0048248 CXCR3 chemokine receptor binding(GO:0048248)
0.1 0.3 GO:0000822 inositol hexakisphosphate binding(GO:0000822)
0.1 0.2 GO:0016842 amidine-lyase activity(GO:0016842)
0.1 0.6 GO:0061133 endopeptidase activator activity(GO:0061133)
0.0 1.5 GO:0003950 NAD+ ADP-ribosyltransferase activity(GO:0003950)
0.0 0.1 GO:0005169 neurotrophin TRKB receptor binding(GO:0005169)
0.0 0.5 GO:0097200 cysteine-type endopeptidase activity involved in execution phase of apoptosis(GO:0097200)
0.0 0.6 GO:0016846 carbon-sulfur lyase activity(GO:0016846)
0.0 0.1 GO:0016749 5-aminolevulinate synthase activity(GO:0003870) N-succinyltransferase activity(GO:0016749)
0.0 0.6 GO:0008239 dipeptidyl-peptidase activity(GO:0008239)
0.0 0.2 GO:0042289 MHC class II protein binding(GO:0042289)
0.0 0.3 GO:0004571 mannosyl-oligosaccharide 1,2-alpha-mannosidase activity(GO:0004571)
0.0 0.3 GO:1990829 C-rich single-stranded DNA binding(GO:1990829)
0.0 0.1 GO:0004828 serine-tRNA ligase activity(GO:0004828)
0.0 0.6 GO:0004129 cytochrome-c oxidase activity(GO:0004129) heme-copper terminal oxidase activity(GO:0015002) oxidoreductase activity, acting on a heme group of donors, oxygen as acceptor(GO:0016676)
0.0 0.1 GO:0004819 glutamine-tRNA ligase activity(GO:0004819)
0.0 0.7 GO:0005164 tumor necrosis factor receptor binding(GO:0005164)
0.0 0.1 GO:0004169 dolichyl-phosphate-mannose-protein mannosyltransferase activity(GO:0004169)
0.0 0.2 GO:0051434 BH3 domain binding(GO:0051434)
0.0 0.4 GO:0042043 neurexin family protein binding(GO:0042043)
0.0 0.4 GO:0001222 transcription corepressor binding(GO:0001222)
0.0 0.2 GO:0008526 phosphatidylinositol transporter activity(GO:0008526)
0.0 0.1 GO:0001515 opioid peptide activity(GO:0001515)
0.0 0.2 GO:0004143 diacylglycerol kinase activity(GO:0004143)
0.0 0.9 GO:0015485 cholesterol binding(GO:0015485)
0.0 0.6 GO:0004812 aminoacyl-tRNA ligase activity(GO:0004812) ligase activity, forming carbon-oxygen bonds(GO:0016875) ligase activity, forming aminoacyl-tRNA and related compounds(GO:0016876)
0.0 0.3 GO:0000062 fatty-acyl-CoA binding(GO:0000062)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.0 ST TYPE I INTERFERON PATHWAY Type I Interferon (alpha/beta IFN) Pathway
0.0 0.8 PID HIF1A PATHWAY Hypoxic and oxygen homeostasis regulation of HIF-1-alpha
0.0 0.6 ST G ALPHA S PATHWAY G alpha s Pathway
0.0 0.9 SA B CELL RECEPTOR COMPLEXES Antigen binding to B cell receptors activates protein tyrosine kinases, such as the Src family, which ultimate activate MAP kinases.
0.0 0.5 SA CASPASE CASCADE Apoptosis is mediated by caspases, cysteine proteases arranged in a proteolytic cascade.
0.0 0.7 PID TRAIL PATHWAY TRAIL signaling pathway
0.0 0.8 PID NFAT TFPATHWAY Calcineurin-regulated NFAT-dependent transcription in lymphocytes

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target  Total log-likelihood Term Description
0.1 1.1 REACTOME INITIAL TRIGGERING OF COMPLEMENT Genes involved in Initial triggering of complement
0.1 1.0 REACTOME IL 6 SIGNALING Genes involved in Interleukin-6 signaling
0.0 0.7 REACTOME EXTRINSIC PATHWAY FOR APOPTOSIS Genes involved in Extrinsic Pathway for Apoptosis
0.0 0.8 REACTOME TETRAHYDROBIOPTERIN BH4 SYNTHESIS RECYCLING SALVAGE AND REGULATION Genes involved in Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation
0.0 0.7 REACTOME MITOCHONDRIAL TRNA AMINOACYLATION Genes involved in Mitochondrial tRNA aminoacylation
0.0 1.3 REACTOME MRNA 3 END PROCESSING Genes involved in mRNA 3'-end processing
0.0 0.8 REACTOME SYNTHESIS AND INTERCONVERSION OF NUCLEOTIDE DI AND TRIPHOSPHATES Genes involved in Synthesis and interconversion of nucleotide di- and triphosphates
0.0 0.4 REACTOME SIGNAL ATTENUATION Genes involved in Signal attenuation
0.0 1.2 REACTOME INTERFERON GAMMA SIGNALING Genes involved in Interferon gamma signaling
0.0 0.3 REACTOME CDC6 ASSOCIATION WITH THE ORC ORIGIN COMPLEX Genes involved in CDC6 association with the ORC:origin complex
0.0 0.5 REACTOME CASPASE MEDIATED CLEAVAGE OF CYTOSKELETAL PROTEINS Genes involved in Caspase-mediated cleavage of cytoskeletal proteins
0.0 0.6 REACTOME RECYCLING PATHWAY OF L1 Genes involved in Recycling pathway of L1
0.0 0.7 REACTOME CROSS PRESENTATION OF SOLUBLE EXOGENOUS ANTIGENS ENDOSOMES Genes involved in Cross-presentation of soluble exogenous antigens (endosomes)
0.0 0.2 REACTOME HOMOLOGOUS RECOMBINATION REPAIR OF REPLICATION INDEPENDENT DOUBLE STRAND BREAKS Genes involved in Homologous recombination repair of replication-independent double-strand breaks
0.0 0.3 REACTOME MRNA DECAY BY 5 TO 3 EXORIBONUCLEASE Genes involved in mRNA Decay by 5' to 3' Exoribonuclease