avrg: GFI1 WT vs 36n/n vs KD

• Motif significance table
• Sample table
• Mean activities
• All promoters sorted by FOV

• Activity table
• Activity delta table
• Regulatory interactions
• Motifs sorted by significance
• Expression table
• Download the whole report

Gene Symbol	Gene ID	Gene Info
Irf5 Links Ensembl NCBI MGI UniProt	ENSMUSG00000029771.13	interferon regulatory factor 5
Irf6 Links Ensembl NCBI MGI UniProt	ENSMUSG00000026638.16	interferon regulatory factor 6

Gene	Promoter	Pearson corr. coef.	P-value	Plot
Irf6	mm39_v1_chr1_+_192835414_192835516	0.78	1.2e-01	Click!
Irf5	mm39_v1_chr6_+_29531247_29531269	0.11	8.6e-01	Click!

Promoter	Log-likelihood	Transcript	Gene	Gene Info
chr4_-_40239778 Show fit	0.27	ENSMUST00000037907.13	Ddx58 Links Ensembl NCBI MGI UniProt Show fit	DEAD/H box helicase 58
chr17_-_79190002 Show fit	0.17	ENSMUST00000024884.5	Eif2ak2 Links Ensembl NCBI MGI UniProt Show fit	eukaryotic translation initiation factor 2-alpha kinase 2
chr3_+_142202642 Show fit	0.15	ENSMUST00000090127.7	Gbp5 Links Ensembl NCBI MGI UniProt Show fit	guanylate binding protein 5
chr6_-_124888643 Show fit	0.13	ENSMUST00000032217.2	Lag3 Links Ensembl NCBI MGI UniProt Show fit	lymphocyte-activation gene 3
chr8_+_72943455 Show fit	0.13	ENSMUST00000072097.14	Hsh2d Links Ensembl NCBI MGI UniProt Show fit	hematopoietic SH2 domain containing
chr11_+_88890202 Show fit	0.12	ENSMUST00000100627.9 ENSMUST00000107896.10 ENSMUST00000000284.7	Trim25 Links Ensembl NCBI MGI UniProt Show fit	tripartite motif-containing 25
chr7_-_125995884 Show fit	0.12	ENSMUST00000075671.5	Nfatc2ip Links Ensembl NCBI MGI UniProt Show fit	nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 2 interacting protein
chr6_-_137548004 Show fit	0.11	ENSMUST00000100841.9	Eps8 Links Ensembl NCBI MGI UniProt Show fit	epidermal growth factor receptor pathway substrate 8
chr16_-_35691914 Show fit	0.11	ENSMUST00000042665.9	Parp14 Links Ensembl NCBI MGI UniProt Show fit	poly (ADP-ribose) polymerase family, member 14
chr4_-_136613498 Show fit	0.11	ENSMUST00000046384.9	C1qb Links Ensembl NCBI MGI UniProt Show fit	complement component 1, q subcomponent, beta polypeptide
chr8_+_72050292 Show fit	0.10	ENSMUST00000143662.8	Niban3 Links Ensembl NCBI MGI UniProt Show fit	niban apoptosis regulator 3
chr17_+_35780977 Show fit	0.09	ENSMUST00000174525.8 ENSMUST00000068291.7	H2-Q10 Links Ensembl NCBI MGI UniProt Show fit	histocompatibility 2, Q region locus 10
chr14_-_78970160 Show fit	0.09	ENSMUST00000226342.3	Dgkh Links Ensembl NCBI MGI UniProt Show fit	diacylglycerol kinase, eta
chr4_-_40239700 Show fit	0.08	ENSMUST00000142055.2	Ddx58 Links Ensembl NCBI MGI UniProt Show fit	DEAD/H box helicase 58
chr12_-_26506422 Show fit	0.07	ENSMUST00000020970.10	Rsad2 Links Ensembl NCBI MGI UniProt Show fit	radical S-adenosyl methionine domain containing 2
chr3_-_32670628 Show fit	0.07	ENSMUST00000193050.2 ENSMUST00000108234.8 ENSMUST00000155737.8	Gnb4 Links Ensembl NCBI MGI UniProt Show fit	guanine nucleotide binding protein (G protein), beta 4
chr9_-_14292453 Show fit	0.07	ENSMUST00000167549.2	Endod1 Links Ensembl NCBI MGI UniProt Show fit	endonuclease domain containing 1
chr12_-_73160181 Show fit	0.07	ENSMUST00000043208.8 ENSMUST00000175693.3	Six4 Links Ensembl NCBI MGI UniProt Show fit	sine oculis-related homeobox 4
chr11_-_86091970 Show fit	0.07	ENSMUST00000044423.4	Brip1 Links Ensembl NCBI MGI UniProt Show fit	BRCA1 interacting protein C-terminal helicase 1
chr16_+_35758836 Show fit	0.06	ENSMUST00000114878.8	Parp9 Links Ensembl NCBI MGI UniProt Show fit	poly (ADP-ribose) polymerase family, member 9
chr5_+_21391282 Show fit	0.06	ENSMUST00000036031.13 ENSMUST00000198937.2	Gsap Links Ensembl NCBI MGI UniProt Show fit	gamma-secretase activating protein
chr1_+_175459559 Show fit	0.06	ENSMUST00000040250.15	Kmo Links Ensembl NCBI MGI UniProt Show fit	kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
chrX_+_36390430 Show fit	0.06	ENSMUST00000016553.5	Nkap Links Ensembl NCBI MGI UniProt Show fit	NFKB activating protein
chr1_+_52158721 Show fit	0.05	ENSMUST00000186057.7	Stat1 Links Ensembl NCBI MGI UniProt Show fit	signal transducer and activator of transcription 1
chr11_+_101473062 Show fit	0.05	ENSMUST00000039581.14 ENSMUST00000100403.9 ENSMUST00000107194.8 ENSMUST00000128614.2	Tmem106a Links Ensembl NCBI MGI UniProt Show fit	transmembrane protein 106A
chr11_+_72580823 Show fit	0.05	ENSMUST00000155998.2	Ankfy1 Links Ensembl NCBI MGI UniProt Show fit	ankyrin repeat and FYVE domain containing 1
chr1_+_52158693 Show fit	0.05	ENSMUST00000189347.7	Stat1 Links Ensembl NCBI MGI UniProt Show fit	signal transducer and activator of transcription 1
chr11_+_72192455 Show fit	0.05	ENSMUST00000151440.8 ENSMUST00000146233.8 ENSMUST00000140842.9	Xaf1 Links Ensembl NCBI MGI UniProt Show fit	XIAP associated factor 1
chrX_-_94488394 Show fit	0.05	ENSMUST00000084535.6	Amer1 Links Ensembl NCBI MGI UniProt Show fit	APC membrane recruitment 1
chr1_+_52158599 Show fit	0.05	ENSMUST00000186574.7 ENSMUST00000070968.14 ENSMUST00000191435.7 ENSMUST00000186857.7 ENSMUST00000188681.7	Stat1 Links Ensembl NCBI MGI UniProt Show fit	signal transducer and activator of transcription 1
chr16_-_91443794 Show fit	0.05	ENSMUST00000232367.2 ENSMUST00000231380.2 ENSMUST00000231444.2 ENSMUST00000232289.2 ENSMUST00000120450.2 ENSMUST00000023684.14	Gart Links Ensembl NCBI MGI UniProt Show fit	phosphoribosylglycinamide formyltransferase
chr11_-_94212783 Show fit	0.04	ENSMUST00000166312.8 ENSMUST00000107821.9 ENSMUST00000021226.14 ENSMUST00000107820.2	Luc7l3 Links Ensembl NCBI MGI UniProt Show fit	LUC7-like 3 (S. cerevisiae)
chr17_-_32408431 Show fit	0.04	ENSMUST00000087721.10 ENSMUST00000162117.3	Ephx3 Links Ensembl NCBI MGI UniProt Show fit	epoxide hydrolase 3
chr1_+_175459735 Show fit	0.04	ENSMUST00000097458.4	Kmo Links Ensembl NCBI MGI UniProt Show fit	kynurenine 3-monooxygenase (kynurenine 3-hydroxylase)
chr7_-_126194097 Show fit	0.04	ENSMUST00000058429.6	Il27 Links Ensembl NCBI MGI UniProt Show fit	interleukin 27
chr6_+_4505493 Show fit	0.04	ENSMUST00000031668.10	Col1a2 Links Ensembl NCBI MGI UniProt Show fit	collagen, type I, alpha 2
chr6_-_39095144 Show fit	0.04	ENSMUST00000038398.7	Parp12 Links Ensembl NCBI MGI UniProt Show fit	poly (ADP-ribose) polymerase family, member 12
chr5_+_34919078 Show fit	0.04	ENSMUST00000080036.3	Htt Links Ensembl NCBI MGI UniProt Show fit	huntingtin
chr16_+_23428650 Show fit	0.04	ENSMUST00000038423.6 ENSMUST00000211349.2	Rtp4 Links Ensembl NCBI MGI UniProt Show fit	receptor transporter protein 4
chr19_+_30007910 Show fit	0.03	ENSMUST00000025739.14	Uhrf2 Links Ensembl NCBI MGI UniProt Show fit	ubiquitin-like, containing PHD and RING finger domains 2
chr16_-_35759461 Show fit	0.03	ENSMUST00000081933.14 ENSMUST00000114885.3	Dtx3l Links Ensembl NCBI MGI UniProt Show fit	deltex 3-like, E3 ubiquitin ligase
chr9_-_123680726 Show fit	0.03	ENSMUST00000084715.14	Fyco1 Links Ensembl NCBI MGI UniProt Show fit	FYVE and coiled-coil domain containing 1
chr7_-_80037622 Show fit	0.03	ENSMUST00000206698.2	Fes Links Ensembl NCBI MGI UniProt Show fit	feline sarcoma oncogene
chrX_+_20714782 Show fit	0.02	ENSMUST00000001155.11 ENSMUST00000122312.8 ENSMUST00000120356.8 ENSMUST00000122850.2	Araf Links Ensembl NCBI MGI UniProt Show fit	Araf proto-oncogene, serine/threonine kinase
chr17_+_34863779 Show fit	0.02	ENSMUST00000174796.2	Fkbpl Links Ensembl NCBI MGI UniProt Show fit	FK506 binding protein-like
chr7_-_131918926 Show fit	0.02	ENSMUST00000080215.6	Chst15 Links Ensembl NCBI MGI UniProt Show fit	carbohydrate sulfotransferase 15
chr15_-_76127600 Show fit	0.02	ENSMUST00000165738.8 ENSMUST00000075689.7	Parp10 Links Ensembl NCBI MGI UniProt Show fit	poly (ADP-ribose) polymerase family, member 10
chr6_-_70313491 Show fit	0.02	ENSMUST00000103388.4	Igkv6-20 Links Ensembl NCBI MGI UniProt Show fit	immunoglobulin kappa variable 6-20
chr5_-_91550853 Show fit	0.02	ENSMUST00000121044.6	Btc Links Ensembl NCBI MGI UniProt Show fit	betacellulin, epidermal growth factor family member
chr1_-_163141230 Show fit	0.02	ENSMUST00000174397.3 ENSMUST00000075805.13	Prrx1 Links Ensembl NCBI MGI UniProt Show fit	paired related homeobox 1
chr4_-_118774662 Show fit	0.02	ENSMUST00000071979.2	Olfr1329 Links Ensembl NCBI MGI UniProt Show fit	olfactory receptor 1329
chr17_-_35081129 Show fit	0.02	ENSMUST00000154526.8	Cfb Links Ensembl NCBI MGI UniProt Show fit	complement factor B
chr9_+_44953723 Show fit	0.02	ENSMUST00000034600.5	Mpzl2 Links Ensembl NCBI MGI UniProt Show fit	myelin protein zero-like 2
chr11_+_60590498 Show fit	0.01	ENSMUST00000052346.10	Llgl1 Links Ensembl NCBI MGI UniProt Show fit	LLGL1 scribble cell polarity complex component
chr11_+_29080733 Show fit	0.01	ENSMUST00000020756.9	Pnpt1 Links Ensembl NCBI MGI UniProt Show fit	polyribonucleotide nucleotidyltransferase 1
chr6_+_57557978 Show fit	0.01	ENSMUST00000031817.10	Herc6 Links Ensembl NCBI MGI UniProt Show fit	hect domain and RLD 6
chr2_-_51824656 Show fit	0.01	ENSMUST00000165313.2	Rbm43 Links Ensembl NCBI MGI UniProt Show fit	RNA binding motif protein 43
chr4_-_46536088 Show fit	0.01	ENSMUST00000102924.3 ENSMUST00000046897.13	Trim14 Links Ensembl NCBI MGI UniProt Show fit	tripartite motif-containing 14
chr2_-_166904902 Show fit	0.01	ENSMUST00000048988.14	Znfx1 Links Ensembl NCBI MGI UniProt Show fit	zinc finger, NFX1-type containing 1
chr7_-_65020655 Show fit	0.01	ENSMUST00000032729.8	Tjp1 Links Ensembl NCBI MGI UniProt Show fit	tight junction protein 1
chr12_-_32000534 Show fit	0.01	ENSMUST00000172314.9	Hbp1 Links Ensembl NCBI MGI UniProt Show fit	high mobility group box transcription factor 1
chr9_+_55234197 Show fit	0.01	ENSMUST00000085754.10 ENSMUST00000034862.5	Tmem266 Links Ensembl NCBI MGI UniProt Show fit	transmembrane protein 266
chr7_+_127160751 Show fit	0.01	ENSMUST00000190278.3	Tmem265 Links Ensembl NCBI MGI UniProt Show fit	transmembrane protein 265
chr1_-_163141278 Show fit	0.01	ENSMUST00000027878.14	Prrx1 Links Ensembl NCBI MGI UniProt Show fit	paired related homeobox 1
chr9_+_95836797 Show fit	0.01	ENSMUST00000034981.14 ENSMUST00000185633.7	Xrn1 Links Ensembl NCBI MGI UniProt Show fit	5'-3' exoribonuclease 1
chr16_+_11131676 Show fit	0.01	ENSMUST00000023140.6	Tnfrsf17 Links Ensembl NCBI MGI UniProt Show fit	tumor necrosis factor receptor superfamily, member 17
chr6_-_146855880 Show fit	0.01	ENSMUST00000111622.2 ENSMUST00000036592.15	1700034J05Rik Links Ensembl NCBI MGI UniProt Show fit	RIKEN cDNA 1700034J05 gene
chr13_-_30170031 Show fit	0.01	ENSMUST00000102948.11	E2f3 Links Ensembl NCBI MGI UniProt Show fit	E2F transcription factor 3
chr9_-_123680927 Show fit	0.01	ENSMUST00000184082.3 ENSMUST00000167595.9	Fyco1 Links Ensembl NCBI MGI UniProt Show fit	FYVE and coiled-coil domain containing 1
chr1_-_105284407 Show fit	0.00	ENSMUST00000172299.2	Rnf152 Links Ensembl NCBI MGI UniProt Show fit	ring finger protein 152
chr16_-_55659194 Show fit	0.00	ENSMUST00000096026.9 ENSMUST00000036273.13 ENSMUST00000114457.8	Nfkbiz Links Ensembl NCBI MGI UniProt Show fit	nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor, zeta
chr13_-_100689105 Show fit	0.00	ENSMUST00000159459.8	Ocln Links Ensembl NCBI MGI UniProt Show fit	occludin
chr2_-_77000936 Show fit	0.00	ENSMUST00000164114.9 ENSMUST00000049544.14	Ccdc141 Links Ensembl NCBI MGI UniProt Show fit	coiled-coil domain containing 141
chr17_+_34863738 Show fit	0.00	ENSMUST00000036720.9	Fkbpl Links Ensembl NCBI MGI UniProt Show fit	FK506 binding protein-like
chr17_+_80597632 Show fit	0.00	ENSMUST00000227729.2 ENSMUST00000061703.10	Morn2 Links Ensembl NCBI MGI UniProt Show fit	MORN repeat containing 2
chr6_-_13607963 Show fit	0.00	ENSMUST00000031554.9 ENSMUST00000149123.3	Tmem168 Links Ensembl NCBI MGI UniProt Show fit	transmembrane protein 168
chr6_-_87815653 Show fit	0.00	ENSMUST00000204431.2 ENSMUST00000089497.7	Isy1 Links Ensembl NCBI MGI UniProt Show fit	ISY1 splicing factor homolog
chr9_-_123691077 Show fit	0.00	ENSMUST00000182350.3	Xcr1 Links Ensembl NCBI MGI UniProt Show fit	chemokine (C motif) receptor 1
chr6_+_70663930 Show fit	0.00	ENSMUST00000103402.2	Igkv3-3 Links Ensembl NCBI MGI UniProt Show fit	immunoglobulin kappa variable 3-3

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Gene overrepresentation in biological process category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.1	0.4	GO:0009597	detection of virus(GO:0009597)
0.1	0.2	GO:0034240	negative regulation of macrophage fusion(GO:0034240)
0.0	0.1	GO:0070212	protein poly-ADP-ribosylation(GO:0070212)
0.0	0.1	GO:0070358	actin polymerization-dependent cell motility(GO:0070358)
0.0	0.1	GO:0019805	quinolinate biosynthetic process(GO:0019805)
0.0	0.1	GO:0010705	meiotic DNA double-strand break processing involved in reciprocal meiotic recombination(GO:0010705) double-strand break repair involved in meiotic recombination(GO:1990918)
0.0	0.1	GO:0051902	negative regulation of mitochondrial depolarization(GO:0051902)
0.0	0.1	GO:0034165	positive regulation of toll-like receptor 9 signaling pathway(GO:0034165)
0.0	0.3	GO:1900225	regulation of NLRP3 inflammasome complex assembly(GO:1900225)
0.0	0.1	GO:0061055	myotome development(GO:0061055)
0.0	0.1	GO:0045085	negative regulation of interleukin-2 biosynthetic process(GO:0045085)

Gene overrepresentation in cellular component category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.0	GO:0005584	collagen type I trimer(GO:0005584)

Gene overrepresentation in molecular function category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.2	GO:0004694	eukaryotic translation initiation factor 2alpha kinase activity(GO:0004694)
0.0	0.1	GO:0042289	MHC class II protein binding(GO:0042289)
0.0	0.0	GO:0004637	phosphoribosylamine-glycine ligase activity(GO:0004637)
0.0	0.2	GO:0031730	CCR5 chemokine receptor binding(GO:0031730)

Gene overrepresentation in curated gene sets: canonical pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.2	ST TYPE I INTERFERON PATHWAY	Type I Interferon (alpha/beta IFN) Pathway

Gene overrepresentation in curated gene sets: REACTOME pathways category:

Log-likelihood per target	Total log-likelihood	Term	Description
0.0	0.5	REACTOME NFKB ACTIVATION THROUGH FADD RIP1 PATHWAY MEDIATED BY CASPASE 8 AND10	Genes involved in NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
0.0	0.1	REACTOME CREATION OF C4 AND C2 ACTIVATORS	Genes involved in Creation of C4 and C2 activators